Designed optimization of a single-step extraction of fucose-containing sulfated polysaccharides from Sargassum sp.
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All extraction factors (acid concentration, time, and temperature) affected the FCSPs yield.
“All extraction factors affected the FCSPs yield.”
Classical extraction treatment with HCl at elevated temperature and during extended time had a detrimental effect on the FCSPs yield.
“The work also revealed that classical extraction treatment with HCl at elevated temperature and during extended time, i.e., a procedure similar to the one used by Black et al. [9], had a detrimental effect on the FCSPs yield”
The HCl treatment apparently disrupted the structural integrity of the fucose-containing polymer and caused degradation of chains built of fucose residues.
“as this treatment apparently disrupted the structural integrity of the fucose-containing polymer and caused degradation of the chains built of fucose residues [19].”
Shorter extraction time yielded lower total FCSPs yields but higher fucose contents in the products.
“Lower total FCSPs yields, but higher fucose contents in the products were obtained with shorter extraction time [19].”
The structural and compositional traits, and possibly the bioactivity, of fucoidan polysaccharides are significantly influenced by extraction parameters.
“the structural and compositional traits, and possibly the bioactivity, of the fucoidan polysaccharides are significantly influenced by the extraction parameters.”
From Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation (2013) · cites this paper as [3]
Classical extraction of fucoidans from brown seaweeds involves multi-step extended aqueous extractions, usually with hot acid (hydrochloric acid).
“Classical extraction of fucoidans from brown seaweeds involves multi-step extended aqueous extractions, usually with hot acid (hydrochloric acid), 3”
From Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation (2013) · cites this paper as [3]
Classical extraction of fucoidans may include calcium addition to promote alginate precipitation during purification.
“and may include calcium addition to promote alginate precipitation during purification, 3,4”
From Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation (2013) · cites this paper as [3]
Use of 0.2 M HCl broke the integrity of the polysaccharide molecules, resulting in a decline of fucose at elevated time and temperature.
“The use of 0.2 M HCl apparently broke the integrity of the polysaccharide molecules resulting in a decline of fucose at elevated time and temperature.3”
From Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation (2013) · cites this paper as [3]
Fucoidans are vulnerable to harsh extraction conditions, and the extraction method significantly influences the yields and polysaccharide composition of extracted fucose-containing sulfated polysaccharides.
“It has recently been demonstrated that fucoidans are vulnerable to harsh extraction conditions and that the extraction method significantly influences the yields and not least the polysaccharide composition of the extracted fucose-containing sulfated polysaccharides.3”
From Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation (2013) · cites this paper as [3]
HPAEC-PAD analysis of the TFA hydrolysate of S. henslowianum confirmed that fucose, galactose, and glucuronic acid were the major constituents of the extracted polysaccharides obtained by the optimized method.
“The HPAEC-PAD analysis of the TFA hydrolysate of S. henslowianum confirmed that fucose, galactose, and glucuronic acid were the major constituents of the extracted polysaccharides obtained by the optimized method.3”
From Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation (2013) · cites this paper as [3]
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- Authors
- Ale, M. T., Mikkelsen, J. D., & Meyer, A. S.
- Affiliations
- Technical University of Denmark (DK)
- Corresponding author
- Meyer, Anne S.
- Venue
- Journal of Applied Phycology
- Published
- 2011-06-02
- Volume
- 24
- Issue
- 4
- Pages
- 715-723
- ISSN
- 0921-8971 (ISSN-L)
- 1573-5176
- OpenAlex
- W1975233753
- Cited by
- 113
- References
- 32
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 13 · 2023: 10 · 2022: 13 · 2021: 10 · 2020: 7 · 2019: 12 · 2018: 7 · 2017: 4 · 2016: 7 · 2015: 5 · 2014: 8 · 2013: 3
- FWCI
- 6.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Journal of Applied Phycology (publishedVersion)
- Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU) (submittedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- Sargassum, brown algae, polysaccharide extraction optimization, hydrochloric acid extraction, extraction temperature, extraction time, acid concentration, polysaccharide yield, polysaccharide degradation, fucose, galactose, glucuronic acid, HPAEC-PAD
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