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Macrophages and microglia in the nervous system
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Citations
Cites
Secretory products of macrophages.
Nathan, C. F. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112815 · Cited by 2,615
Perry, V. H., Hume, D. A., & Gordon, S. (1985) · Neuroscience · doi:10.1016/0306-4522(85)90215-5 · Cited by 902
Self-citation
Cited by
Kettenmann, H., Hanisch, U.-K., Noda, M., & Verkhratsky, A. (2011) · Physiological Reviews · doi:10.1152/physrev.00011.2010 · Cited by 3,547
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
Lawson, L. J., Perry, V. H., Dri, P., & Gordon, S. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90229-w · Cited by 2,045
Self-citationMicroglia-specific localisation of a novel calcium binding protein, Iba1
Ito, D., Imai, Y., Ohsawa, K., Nakajima, K., Fukuuchi, Y., & Kohsaka, S. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(98)00040-0 · Cited by 1,476
Microglial Dysfunction and Defective β-Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice
Hickman, S. E., Allison, E. K., & El Khoury, J. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.0616-08.2008 · Cited by 1,329
“Microglia, the mononuclear phagocytes of the brain (Perry and Gordon, 1988), accumulate in senile plaques in AD patients and in animal models of AD (McGeer et al.”
Systemic infections and inflammation affect chronic neurodegeneration
Perry, V. H., Cunningham, C., & Holmes, C. (2007) · Nature Reviews Immunology · doi:10.1038/nri2015 · Cited by 1,027
Self-citationDown-Regulation of the Macrophage Lineage Through Interaction with OX2 (CD200)
Hoek, R. M., Ruuls, S. R., Murphy, C. A., Wright, G. J., Goddard, R., Zurawski, S. M., Blom, B., Homola, M. E., Streit, W. J., Brown, M. H., et al. (2000) · Science · doi:10.1126/science.290.5497.1768 · Cited by 1,022
El Khoury, J., Toft, M., Hickman, S. E., Means, T. K., Terada, K., Geula, C., & Luster, A. D. (2007) · Nature Medicine · doi:10.1038/nm1555 · Cited by 915
Turnover of resident microglia in the normal adult mouse brain
Lawson, L. J., Perry, V. H., & Gordon, S. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90500-2 · Cited by 709
Self-citationErblich, B., Zhu, L., Etgen, A. M., Dobrenis, K., & Pollard, J. W. (2011) · PLoS ONE · doi:10.1371/journal.pone.0026317 · Cited by 649
Microglia activation in retinal degeneration
Langmann, T. (2007) · Journal of Leukocyte Biology · doi:10.1189/jlb.0207114 · Cited by 496
Mittelbronn, M., Dietz, K., Schluesener, H. J., & Meyermann, R. (2001) · Acta Neuropathologica · doi:10.1007/s004010000284 · Cited by 482
The impact of systemic infection on the progression of neurodegenerative disease
Perry, V. H., Newman, T. A., & Cunningham, C. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1032 · Cited by 428
Self-citationCai, Y., Liu, J., Wang, B., Sun, M., & Yang, H. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.856376 · Cited by 351
Bone marrow derived elements and resident microglia in brain inflammation
Lassmann, H., Schmied, M., Vass, K., & Hickey, W. F. (1993) · Glia · doi:10.1002/glia.440070106 · Cited by 280
Janabi, N., Peudenier, S., Héron, B., Ng, K. H., & Tardieu, M. (1995) · Neuroscience Letters · doi:10.1016/0304-3940(94)11792-h · Cited by 280
Astrocytes Regulate Microglial Phagocytosis of Senile Plaque Cores of Alzheimer's Disease
DeWitt, D. A., Perry, G., Cohen, M., Doller, C., & Silver, J. (1998) · Experimental Neurology · doi:10.1006/exnr.1997.6738 · Cited by 261
The Axon-Myelin Unit in Development and Degenerative Disease
Stassart, R. M., Möbius, W., Nave, K.-A., & Edgar, J. M. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00467 · Cited by 246
Cosenza;, M. A., Zhao;, M., Si;, Q., & Lee, S. C. (2002) · Brain Pathology · doi:10.1111/j.1750-3639.2002.tb00461.x · Cited by 238
Rymo, S. F., Gerhardt, H., Wolfhagen Sand, F., Lang, R., Uv, A., & Betsholtz, C. (2011) · PLoS ONE · doi:10.1371/journal.pone.0015846 · Cited by 235
Down’s syndrome, neuroinflammation, and Alzheimer neuropathogenesis
Wilcock, D. M., & Griffin, W. S. T. (2013) · Journal of Neuroinflammation · doi:10.1186/1742-2094-10-84 · Cited by 230
Brain interleukin 1 gene expression induced by peripheral lipopolysaccharide administration
BAN, E. (1992) · Cytokine · doi:10.1016/1043-4666(92)90036-q · Cited by 220
Buckman, L. B., Hasty, A. H., Flaherty, D. K., Buckman, C. T., Thompson, M. M., Matlock, B. K., Weller, K., & Ellacott, K. L. J. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2013.06.007 · Cited by 216
GM‐CSF promotes proliferation of human fetal and adult microglia in primary cultures
Lee, S. C., Liu, W., Brosnan, C. F., & Dickson, D. W. (1994) · Glia · doi:10.1002/glia.440120407 · Cited by 209
Naert, G., & Rivest, S. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.0299-11.2011 · Cited by 207
“In particular, microglia, the mononuclear phagocytes of the brain (Perry and Gordon, 1988), are attracted around amyloid plaques and originate in part from the periphery (Malm et al., 2005; Stalder et al., 2005; Simard et al., 2006).”
BackgroundCuadros, M. A., Martin, C., Coltey, P., Almendros, A., & Navascués, J. (1993) · Journal of Comparative Neurology · doi:10.1002/cne.903300110 · Cited by 192
Dysregulated neuronal–microglial cross-talk during aging, stress and inflammation
Jurgens, H. A., & Johnson, R. W. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2010.11.014 · Cited by 179
Dick, A. D., Ford, A. L., Forrester, J. V., & Sedgwick, J. D. (1995) · British Journal of Ophthalmology · doi:10.1136/bjo.79.9.834 · Cited by 129
Targeting innate immunity for neurodegenerative disorders of the central nervous system
Andreasson, K. I., Bachstetter, A. D., Colonna, M., Ginhoux, F., Holmes, C., Lamb, B., Landreth, G., Lee, D. C., Low, D., Lynch, M. A., et al. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13667 · Cited by 126
A deficiency in CCR2+ monocytes: the hidden side of Alzheimer’s disease
Naert, G., & Rivest, S. (2013) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjt028 · Cited by 123
Neuropathological and Genetic Findings in Autism: The Significance of a Putative Minicolumnopathy
Casanova, M. F. (2006) · The Neuroscientist · doi:10.1177/1073858406290375 · Cited by 109
Neuroinflammation in the Aging Down Syndrome Brain; Lessons from Alzheimer's Disease
Wilcock, D. M. (2012) · Current Gerontology and Geriatrics Research · doi:10.1155/2012/170276 · Cited by 104
CD163 Identifies a Unique Population of Ramified Microglia in HIV Encephalitis (HIVE)
Roberts, E. S., Masliah, E., & Fox, H. S. (2004) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/63.12.1255 · Cited by 100
The response of central glia to peripheral nerve injury
Svensson, M., Eriksson, P., Persson, J. K. E., Molander, C., Arvidsson, J., & Aldskogius, H. (1993) · Brain Research Bulletin · doi:10.1016/0361-9230(93)90284-i · Cited by 97
Walker, W. S., Gatewood, J., Olivas, E., Askew, D., & Havenith, C. E. G. (1995) · Journal of Neuroimmunology · doi:10.1016/0165-5728(95)00146-8 · Cited by 91
MHC class II exacerbates demyelination in vivo independently of T cells
Hiremath, M. M., Chen, V. S., Suzuki, K., Ting, J. P.-Y., & Matsushima, G. K. (2008) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2008.06.034 · Cited by 77
Yan, L., Lee, S., Lazzaro, D. R., Aranda, J., Grant, M. B., & Chaqour, B. (2015) · Journal of Biological Chemistry · doi:10.1074/jbc.m115.646950 · Cited by 73
AUBOURG, P., & MANDEL, J. (1996) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1996.tb18637.x · Cited by 58
Mutnal, M. B., Hu, S., Little, M. R., & Lokensgard, J. R. (2011) · Journal of NeuroVirology · doi:10.1007/s13365-011-0042-5 · Cited by 51
CD45 Isoform Expression in Microglia and Inflammatory Cells in HIV‐1 Encephalitis
Cosenza‐Nashat, M. A., Kim, M., Zhao, M., Suh, H., & Lee, S. C. (2006) · Brain Pathology · doi:10.1111/j.1750-3639.2006.00027.x · Cited by 43
Rezaie, P., & Male, D. (2002) · Neuroembryology and Aging · doi:10.1159/000051020 · Cited by 34
Metadata
- Authors
- Perry, V. H., & Gordon, S.
- Venue
- Trends in Neurosciences
- Publisher
- Elsevier BV
- Published
- 1988-01
- Volume
- 11
- Issue
- 6
- Pages
- 273-277
- ISSN
- 0166-2236 (ISSN-L)
- OpenAlex
- W2056351034
- Cited by
- 745
- References
- 2
- FWCI
- 2.13
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.