Cited by 339Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsDementia and Cognitive Impairment Research

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Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat

May, Patrick C., Lampert-Etchells, Martha, Johnson, Steven A., Poirier, Judes, Masters, Jeffrey N., Finch, Caleb E.·1990·Neuron

DOI 10.1016/0896-6273(90)90342-d

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Abstract

A hippocampal poly(A) RNA, pADHC-9, was cloned by differential screening of a human hippocampal cDNA library. By RNA blot analysis, pADHC-9 was elevated 2-fold in Alzheimer's disease hippocampus. In situ analyses identified pADHC-9 expression in pyramidal and non-pyramidal cells of the hippocampus and entorhinal cortex. Nucleotide sequence analysis identified pADHC-9 as a potential human homolog of rat sulfated glycoprotein 2 (SGP-2). SGP-2 expression increased in rat hippocampus following experimental lesions that mimic intrinsic neuronal loss and/or deafferentation. The function of pADHC-9 in brain has not been defined, but in serum, a similar protein inhibits complement-dependent cytolysis. Increased expression of pADHC-9 in Alzheimer's disease hippocampus may be a compensatory response mounted to retard a complement-driven neurodegenerative cascade.

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Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
Feinberg, A. P., & Vogelstein, B. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90418-9 · Cited by 24,512
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
Chirgwin, J. M., Przybyla, A., MacDonald, R. J., & Rutter, W. J. (1979) · Biochemistry · doi:10.1021/bi00591a005 · Cited by 21,725
A simple and very efficient method for generating cDNA libraries
Gubler, U., & Hoffman, B. J. (1983) · Gene · doi:10.1016/0378-1119(83)90230-5 · Cited by 4,461
Alzheimer's disease: cell-specific pathology isolates the hippocampal formation.
Hyman, B. T., Van Hoesen, G. W., Damasio, A. R., & Barnes, C. L. (1984) · Science · doi:10.1126/science.6474172 · Cited by 2,268
Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
Nadler, J. V., Perry, B. W., & Cotman, C. W. (1978) · Nature · doi:10.1038/271676a0 · Cited by 745
Expression of immune system-associated antigens by cells of the human central nervous system: Relationship to the pathology of Alzheimer's disease
Rogers, J., Luber-Narod, J., Styren, S. D., & Civin, W. H. (1988) · Neurobiology of Aging · doi:10.1016/s0197-4580(88)80079-4 · Cited by 743
Perforant pathway changes and the memory impairment of Alzheimer's disease
Hyman, B. T., Van Hoesen, G. W., Kromer, L. J., & Damasio, A. R. (1986) · Annals of Neurology · doi:10.1002/ana.410200406 · Cited by 672
Developmentally regulated expression of specific tau sequences
Kosik, K. S., Orecchio, L. D., Bakalis, S., & Neve, R. L. (1989) · Neuron · doi:10.1016/0896-6273(89)90077-9 · Cited by 598
Plasticity of Hippocampal Circuitry in Alzheimer's Disease
Geddes, J. W., Monaghan, D. T., Cotman, C. W., Lott, I. T., Kim, R. C., & Chui, H. C. (1985) · Science · doi:10.1126/science.4071042 · Cited by 461

Show all 30 references

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Rogers, J., Cooper, N. R., Webster, S., Schultz, J., McGeer, P. L., Styren, S. D., Civin, W. H., Brachova, L., Bradt, B., & Ward, P. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.21.10016 · Cited by 817
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Rogers, J., Webster, S. D., Lue, L., Brachova, L., CIVIN, W. H., Emmerling, M. R., Shivers, B. D., Walker, D. G., & McGeer, P. L. (1996) · Neurobiology of Aging · doi:10.1016/0197-4580(96)00115-7 · Cited by 438
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Rosenberg, M. E., & Silkensen, J. R. (1995) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/1357-2725(95)00027-m · Cited by 427
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Gasque, P., Dean, Y. D., McGreal, E. P., VanBeek, J., & Morgan, B. P. (2000) · Immunopharmacology · doi:10.1016/s0162-3109(00)80302-1 · Cited by 343
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Puchades, M., Hansson, S. F., Nilsson, C. L., Andreasen, N., Blennow, K., & Davidsson, P. (2003) · Molecular Brain Research · doi:10.1016/j.molbrainres.2003.08.005 · Cited by 245
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Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer’s disease.
LeBlanc, A., Liu, H., Goodyer, C., Bergeron, C., & Hammond, J. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.33.23426 · Cited by 232
Active cell death in hormone-dependent tissues
Tenniswood, M., Guenette, R. S., Lakins, J. N., Mooibroek, M. J., WONG, P. W. K., & Welsh, J. (1992) · Cancer and Metastasis Reviews · doi:10.1007/bf00048064 · Cited by 258
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Webster, S. D., Lue, L., Brachova, L., Tenner, A. J., McGeer, P. L., Terai, K., Walker, D. G., Bradt, B. M., Cooper, N. R., & Rogers, J. (1997) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00042-0 · Cited by 258
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Vance, J. E., Hayashi, H., & Karten, B. (2005) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2005.01.005 · Cited by 225
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Kounnas, M. Z., Loukinova, E. B., Stefansson, S., Harmony, J. A. K., Brewer, B., Strickland, D. K., & Argraves, W. S. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.22.13070 · Cited by 227
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Bertrand, P., Poirier, J., Oda, T., Finch, C. E., & Pasinetti, G. M. (1995) · Molecular Brain Research · doi:10.1016/0169-328x(95)00097-c · Cited by 210
Self-citation
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Barnum, S. R. (1995) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411950060020301 · Cited by 207
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Han, B. H., Demattos, R. B., Dugan, L. L., Kim‐Han, J. S., Brendza, R. P., Fryer, J. D., Kierson, M., Cirrito, J. R., Quick, K. L., Harmony, J. A. K., et al. (2001) · Nature Medicine · doi:10.1038/85487 · Cited by 208
Apolipoproteins in the brain: implications for neurological and psychiatric disorders
Elliott, D. A., Weickert, C. S., & Garner, B. (2010) · Clinical Lipidology · doi:10.2217/clp.10.37 · Cited by 194
Apolipoprotein J expression at fluid-tissue interfaces: potential role in barrier cytoprotection.
Aronow, B. J., Lund, S., Brown, T. L., Harmony, J. A. K., & Witte, D. P. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.2.725 · Cited by 197
Characterization of Apolipoprotein J-Alzheimer's Aβ Interaction
Matsubara, E., Frangione, B., & Ghiso, J. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.13.7563 · Cited by 153
Stress-induced transcription of the clusterin/apoJ gene
Michel, D., Chatelain, G., North, S., & Brun, G. (1997) · Biochemical Journal · doi:10.1042/bj3280045 · Cited by 195
The neurobiology of apolipoproteins and their receptors in the CNS and Alzheimer's disease
Beffert, U. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00008-3 · Cited by 190
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Wyatt, A. R., Yerbury, J. J., Ecroyd, H. W., & Wilson, M. R. (2013) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-072711-163904 · Cited by 187
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Viard, I., Wehrli, P., Jornot, L., Bullani, R. R., Vechietti, J.-L., French, L. E., Schifferli, J. A., & Tschopp, J. (1999) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1999.00531.x · Cited by 181
Complement mRNA in the mammalian brain: Responses to Alzheimer's disease and experimental brain lesioning
Johnson, S. A., Lampert-Etchells, M., Pasinetti, G. M., Rozovsky, I., & Finch, C. E. (1992) · Neurobiology of Aging · doi:10.1016/0197-4580(92)90086-d · Cited by 176
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Self-citation
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Kalman, J. L., Juhász, A., Laird, G., Dickens, P., Járdánházy, T., Rimanóczy, Á., Boncz, I., Parry-Jones, W. L., & Janka, Z. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1997.tb00275.x · Cited by 168
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Lidström, A.-M., Bogdanović, N., Hesse, C., Volkmann, I., Davidsson, P., & Blennow, K. (1998) · Experimental Neurology · doi:10.1006/exnr.1998.6892 · Cited by 163
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Leduc, V., Jasmin, S. B., & Poirier, J. (2010) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2010.07.008 · Cited by 166
Self-citation
Human clusterin gene expression is confined to surviving cells during in vitro programmed cell death.
French, L. E., Wohlwend, A., Sappino, A. P., Tschopp, J., & Schifferli, J. A. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117043 · Cited by 160
Molecular characterization of human TRPM‐2/clusterin, a gene associated with sperm maturation, apoptosis and neurodegeneration
WONG, P. W. K., Taillefer, D., Lakins, J. N., Pineault, J. M., Chader, G. J., & Tenniswood, M. (1994) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1994.tb18807.x · Cited by 159
More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration
Lane-Donovan, C., Philips, G. T., & Herz, J. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.005 · Cited by 158
Clusterin (SGP‐2): A multifunctional glycoprotein with regional expression in astrocytes and neurons of the adult rat brain
Pasinetti, G. M., Johnson, S. A., Oda, T., Rozovsky, I., & Finch, C. E. (1994) · The Journal of Comparative Neurology · doi:10.1002/cne.903390307 · Cited by 155
Self-citation
Late-Onset Alzheimer’s Disease Genes and the Potentially Implicated Pathways
Rosenthal, S. L., & Kamboh, M. I. (2014) · Current Genetic Medicine Reports · doi:10.1007/s40142-014-0034-x · Cited by 162
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Wojtas, A., Kang, S. S., Olley, B. M., Gatherer, M., Shinohara, M., Lozano, P. A., Liu, C., Kurti, A., Baker, K. E., Dickson, D. W., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1701137114 · Cited by 147
Antisense TRPM-2 oligodeoxynucleotides chemosensitize human androgen-independent PC-3 prostate cancer cells both in vitro and in vivo.
Miyake, H., Chi, K. N., & Gleave, M. E. (2000) · PubMed · Cited by 150
Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets
Nizami, S., Hall‐Roberts, H., Warrier, S., Cowley, S. A., & Di Daniel, E. (2019) · British Journal of Pharmacology · doi:10.1111/bph.14618 · Cited by 147
Enhanced radiation sensitivity in prostate cancer by inhibition of the cell survival protein clusterin.
Zellweger, T., Chi, K., Miyake, H., Adomat, H. H., Kiyama, S., Skov, K. A., & Gleave, M. E. (2002) · PubMed · Cited by 147
Clusterin as a therapeutic target
Wilson, M. R., & Zoubeidi, A. (2016) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2017.1267142 · Cited by 142
Programmed cell death: Implications for neuropsychiatric disorders
Margolis, R. L., Chuang, D., & Post, R. M. (1994) · Biological Psychiatry · doi:10.1016/0006-3223(94)91241-6 · Cited by 143
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Holtzman, D. M. (2004) · Journal of Molecular Neuroscience · doi:10.1385/jmn:23:3:247 · Cited by 139
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Pasinetti, G. M., Johnson, S. A., Rozovsky, I., Lampert-Etchells, M., Morgan, D., Gordon, M. N., Morgan, T. E., Willoughby, D., & Finch, C. E. (1992) · Experimental Neurology · doi:10.1016/0014-4886(92)90028-o · Cited by 138
Self-citation
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Zellweger, T., Miyake, H., Cooper, S. R., Chi, K., Conklin, B., Monia, B. P., & Gleave, M. E. (2001) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)29459-3 · Cited by 133
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Kim, D., Yeo, S. H., Park, J.-M., Choi, J. Y., Lee, T.-H., Park, S. Y., Ock, M. S., Eo, J., Kim, H., & Cha, H. (2014) · Gene · doi:10.1016/j.gene.2014.05.031 · Cited by 132
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French, L. E., Chonn, A., Ducrest, D., Baumann, B., Belin, D., Wohlwend, A., Kiss, J., Sappino, A.-P., Tschopp, J., & Schifferli, J. A. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.122.5.1119 · Cited by 125
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Kossmann, T., Stahel, P. F., Morganti-Kossmann, M. C., Jones, J. L., & Barnum, S. R. (1997) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(96)00164-6 · Cited by 124
Behavioural, physiological and morphological analysis of a line of apolipoprotein E knockout mouse
Anderson, R., Barnes, J. C., Bliss, T. V. P., Cain, D. P., Cambon, K., Davies, H. A., Errington, M. L., Fellows, L. A., Gray, R. A., Hoh, T., et al. (1998) · Neuroscience · doi:10.1016/s0306-4522(97)00598-8 · Cited by 119
The lurcher gene induces apoptotic death in cerebellar Purkinje cells
Norman, D. J., Feng, L., Cheng, S. S., Gubbay, J., Chan, E. W., & Heintz, N. (1995) · Development · doi:10.1242/dev.121.4.1183 · Cited by 116
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de la Monte, S. M., Ghanbari, K., Frey, W. H., Beheshti, I., Averback, P., Hauser, S. L., Ghanbari, H. A., & Wands, J. R. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119864 · Cited by 114
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Naruse, I., & Keino, H. (1995) · Progress in Neurobiology · doi:10.1016/0301-0082(95)00024-p · Cited by 115
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Bellander, B., von Holst, H., Fredman, P., & Svensson, M. A. (1996) · Journal of neurosurgery · doi:10.3171/jns.1996.85.3.0468 · Cited by 112
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Day, J. R., Laping, N. J., McNeill, T. H., Schreiber, S. S., Pasinetti, G. M., & Finch, C. E. (1990) · Molecular Endocrinology · doi:10.1210/mend-4-12-1995 · Cited by 113
Self-citation
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Murray, K. D., Gall, C. M., Jones, E. G., & Isackson, P. J. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90202-x · Cited by 113
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Lakins, J. N., Bennett, S. A. L., Chen, J.-H., Arnold, J. M., Morrissey, C. M., WONG, P. W. K., O'Sullivan, J. N., & Tenniswood, M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.43.27887 · Cited by 107
Clusterin: A Role in Cell Survival in the Face of Apoptosis?
Koch-Brandt, C., & Morgans, C. W. (1996) · Progress in molecular and subcellular biology · doi:10.1007/978-3-642-79850-4_8 · Cited by 104
Transforming growth factor-β1 induces neuronal and astrocyte genes: Tubulin α1, glial fibrillary acidic protein and clusterin
Laping, N. J., Morgan, T. E., Nichols, N. R., Rozovsky, I., Young-Chan, C. S., Zarow, C., & Finch, C. E. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90081-7 · Cited by 101
Self-citation
Clusterin secreted from astrocyte promotes excitatory synaptic transmission and ameliorates Alzheimer’s disease neuropathology
Chen, F., Swartzlander, D. B., Ghosh, A., Fryer, J. D., Wang, B., & Zheng, H. (2021) · Molecular Neurodegeneration · doi:10.1186/s13024-021-00426-7 · Cited by 103
Lack of correspondence between mRNA expression for a putative cell death molecule (SGP‐2) and neuronal cell death in the central nervous system
Garden, G. A., Bothwell, M. A., & Rubel, E. W. (1991) · Journal of Neurobiology · doi:10.1002/neu.480220605 · Cited by 98
Apolipoprotein E and lipid homeostasis in the etiology and treatment of sporadic Alzheimer's disease
Poirier, J., Miron, J., Picard, C., Gormley, P., Théroux, L., Breitner, J. C. S., & Dea, D. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.03.037 · Cited by 101
Self-citation
Functional and structural properties of lipid-associated apolipoprotein J (clusterin)
CALERO, M., TOKUDA, T., ROSTAGNO, A., KUMAR, A., ZLOKOVIC, B., FRANGIONE, B., & GHISO, J. (1999) · Biochemical Journal · doi:10.1042/bj3440375 · Cited by 98
Inflammation and Alzheimer's Disease: Relationships between Pathogenic Mechanisms and Clinical Expression
Eikelenboom, P., Rozemüller, A. J. M., & Muiswinkel, F. L. V. (1998) · Experimental Neurology · doi:10.1006/exnr.1998.6920 · Cited by 98
Amyloid β-protein precursor: new clues to the genesis of Alzheimer's disease
Selkoe, D. J. (1994) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(94)90014-0 · Cited by 96
Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk
Bettens, K., Brouwers, N., Engelborghs, S., Lambert, J., Rogaeva, E. A., Vandenberghe, R. R., Bastard, N. L., Pasquier, F., Vermeulen, S., Dongen, J. V., et al. (2012) · Molecular Neurodegeneration · doi:10.1186/1750-1326-7-3 · Cited by 98
Selective expression of clusterin (SGP-2) and complement C1qB and C4 during responses to neurotoxinsin vivo andin vitro
Rozovsky, I., Morgan, T. E., Willoughby, D. A., Dugich‐Djordjevic, M. M., Pasinetti, G. M., Johnson, S. A., & Finch, C. E. (1994) · Neuroscience · doi:10.1016/0306-4522(94)90473-1 · Cited by 93
Self-citation
The Reelin Receptors Apolipoprotein E receptor 2 (ApoER2) and VLDL Receptor
Dlugosz, P., & Nimpf, J. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19103090 · Cited by 91
Possible neuroprotective role of clusterin in Alzheimer's disease: a quantitative immunocytochemical study
Giannakopoulos, P., Kövari, E., French, L. E., Viard, I., Hof, P. R., & Bouras, C. (1998) · Acta Neuropathologica · doi:10.1007/s004010050815 · Cited by 90
Intracellular Clusterin Interacts with Brain Isoforms of the Bridging Integrator 1 and with the Microtubule-Associated Protein Tau in Alzheimer's Disease
Zhou, Y., Hayashi, I., Wong, J., Tugusheva, K., Renger, J. J., & Zerbinatti, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0103187 · Cited by 72
Human gliomas and epileptic foci express high levels of a mRNA related to rat testicular sulfated glycoprotein 2, a purported marker of cell death.
Danik, M., Chabot, J., Mercier, C., Benabid, A., Chauvin, C., Quirion, R., & Suh, M. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.19.8577 · Cited by 88
Inflammation in Alzheimer’s Disease and Molecular Genetics: Recent Update
Zhang, Z., Li, Y., Ng, C. T., & Song, Y. (2015) · Archivum Immunologiae et Therapiae Experimentalis · doi:10.1007/s00005-015-0351-0 · Cited by 92
The early contribution of cerebrovascular factors to the pathogenesis of Alzheimer’s disease
Pimentel‐Coelho, P. M., & Rivest, S. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08126.x · Cited by 87
Identification of molecular aggregates containing glycoproteins III, J, K (carboxypeptidase H), and H (Kex2-related proteases) in the soluble and membrane fractions of adrenal medullary chromaffin granules.
Palmer, D. J., & Christie, D. L. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)88625-8 · Cited by 85
Localization of sulfated glycoprotein‐2/clusterin mRNA in the rat brain by in situ hybridization
Danik, M., Chabot, J., Hassan‐gonzalez, D., Suh, M., & Quirion, R. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903340205 · Cited by 82
Mouse apolipoprotein J: characterization of a gene implicated in atherosclerosis.
Jordan-Starck, T. C., Lund, S., Witte, D. P., Aronow, B. J., Ley, C. A., Stuart, W. D., Swertfeger, D. K., Clayton, L., Sells, S. F., & Paigen, B. J. (1994) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)41208-8 · Cited by 83
The Impact of Cholesterol, DHA, and Sphingolipids on Alzheimer’s Disease
Grimm, M. O. W., Zimmer, V. C., Lehmann, J., Grimm, H. S., & Hartmann, T. (2013) · BioMed Research International · doi:10.1155/2013/814390 · Cited by 85
Clusterin levels are increased in A lzheimer's disease and influence the regional distribution of Aβ
Miners, J. S., Clarke, P., & Love, S. (2016) · Brain Pathology · doi:10.1111/bpa.12392 · Cited by 83
Complement activation and β-amyloid-mediated neurotoxicity in Alzheimer's disease
Rogers, J., Schultz, J., Brachova, L., Lue, L. F., Webster, S. M., Bradt, B. M., Cooper, N. R., & Moss, D. E. (1992) · Research in Immunology · doi:10.1016/0923-2494(92)80046-n · Cited by 82

Authors: May, P. C., Lampert-Etchells, M., Johnson, S. A., Poirier, J., Masters, J. N., & Finch, C. E.
Affiliations: University of Southern California (US)
ORCID: May, Patrick C.
Poirier, Judes
Finch, Caleb E.
Venue: Neuron
Publisher: Elsevier BV
Published: 1990-12
Volume: 5
Issue: 6
Pages: 831-839
ISSN: 0896-6273 (ISSN-L)
DOI: 10.1016/0896-6273(90)90342-d
OpenAlex: W2004102314
Cited by: 339
References: 30
Citations by year: 2026: 3 · 2025: 3 · 2024: 7 · 2023: 5 · 2022: 4 · 2021: 7 · 2020: 6 · 2019: 10 · 2018: 8 · 2017: 7 · 2016: 9 · 2015: 10 · 2014: 11 · 2013: 10 · 2012: 12
FWCI: 15.87
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuron (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Aging (AG 05142, P50AG005142)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Keywords: Alzheimer's disease, hippocampus, gene expression, sulfated glycoprotein-2, polyadenylated RNA, entorhinal cortex, experimental brain lesions, deafferentation, neuronal loss, complement-dependent cytotoxicity, neurodegeneration, compensatory response
MeSH terms: Alzheimer Disease, Autoradiography, Cloning, Molecular, Denervation, DNA, Glycoproteins, Hippocampus, Humans, Male, Nucleic Acid Hybridization, RNA, Transcription, Genetic, DNA Probes, Gene Expression, Molecular Chaperones, Clusterin

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Dynamics of gene expression for a hippocampal glycoprotein elevated in Alzheimer's disease and in response to experimental lesions in rat

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