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The oligodendrocyte and its many cellular processes
Abstract
The oligodendrocyte (OL) is increasingly providing a model system for probing central issues of cell biology. During development, OL progenitors undergo controlled migration, proliferation and differentiation, secrete and respond to a number of growth factors, and dramatically change their cellular architecture, culminating in the formation of the myelin sheath. This review examines some facets of the OL that make it an especially attractive tool for studying many basic questions in cell biology.
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“Myelination requires dramatic changes in the cellular architecture of differentiating glia and a high degree of cell polarization that partitions the plasma membrane into distinct domains (Pfeiffer et al., 1993).”
From SH3TC2, a protein mutant in Charcot–Marie–Tooth neuropathy, links peripheral nerve myelination to endosomal recycling (2010) · cites this paper as Pfeiffer et al., 1993
Citations
Cites
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Metadata
- Authors
- PFEIFFER, S., WARRINGTON, A., & BANSAL, R.
- Venue
- Trends in Cell Biology
- Publisher
- Elsevier BV
- Published
- 1993-06
- Volume
- 3
- Issue
- 6
- Pages
- 191-197
- ISSN
- 0962-8924
- Cited by
- 737
- References
- 1
- Language
- en
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