The DOI matches its Crossref record; 147 of the 151 references it cites were found in a registry or an index.
Addictions Neuroclinical Assessment: A Neuroscience-Based Framework for Addictive Disorders
Open accessAbstract
This paper proposes a heuristic framework for an Addictions Neuroclinical Assessment (ANA) that incorporates key functional domains derived from the neurocircuitry of addiction. We review how addictive disorders (AD) are presently diagnosed, and the need for new neuroclinical measures to differentiate patients who meet clinical criteria for addiction to the same agent while differing in etiology, prognosis and treatment response. The need for a better understanding of the mechanisms provoking and maintaining addiction, as evidenced by the limitations of current treatments and within-diagnosis clinical heterogeneity, is articulated. In addition, recent changes in the nosology of AD, challenges to current classification systems, and prior attempts to subtype individuals with AD are described. Complementary initiatives, including the Research Domain Criteria (RDoC) project, which have established frameworks for the neuroscience of psychiatric disorders, are discussed. Three domains, executive function, incentive salience, and negative emotionality, tied to different phases in the cycle of addiction, form the core functional elements of AD. Measurement of these domains in epidemiologic, genetic, clinical, and treatment studies will provide the underpinnings for an understanding of cross-population and temporal variation in addictions, shared mechanisms in addictive disorders, impact of changing environmental influences, and gene identification. Finally, we show that it is practical to implement such a deep neuroclinical assessment using a combination of neuroimaging and performance measures. Neuroclinical assessment is key to reconceptualizing the nosology of AD on the basis of process and etiology, an advance that can lead to improved prevention and treatment.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Advances in diagnosis that reflect such an endophenotype or research domain criterion approach will synergistically combine with advances in neurobiology to promote novel pharmacotherapeutic, brain stimulation (ie, transcranial magnetic stimulation and direct electrical stimulation), and behavioural treatments.186”
From Neurobiology of addiction: a neurocircuitry analysis (2016) · cites this paper as [186]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Using the Addictions Neuroclinical Assessment, five subdomains of negative emotional states that can be operationally measured in human laboratory settings and paralleled by animal models were outlined (Kwako et al., 2016).”
From Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development (2021) · cites this paper as Kwako et al., 2016
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“From a nosology perspective, the Addictions Neuroclinical Assessment framework allows the identification of individuals with phenotypes that signal dysregulation in this domain (Kwako et al., 2016).”
From Drug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development (2021) · cites this paper as Kwako et al., 2016
Experimental — accuracy not yet measuredIn the citing paper
“a neurofunctional domain that is postulated to be relevant to early onset of risky alcohol use and the development and maintenance of AUDs (15).”
From Impact of Childhood Trauma on Executive Function in Adolescence—Mediating Functional Brain Networks and Prediction of High-Risk Drinking (2020) · cites this paper as [15]
In the citing paper
“third, it integrates measures for an understanding of the overall functioning of a domain”
From Addiction Biomarkers: Dimensional Approaches to Understanding Addiction (2018) · cites this paper as [2]
In the citing paper
“The ANA domains, which encompass only a small fraction of the biomarker space for addiction, are incentive salience (see Glossary), negative emotionality, and executive function [2].”
From Addiction Biomarkers: Dimensional Approaches to Understanding Addiction (2018) · cites this paper as [2]
In the citing paper
“The ANA domains, which encompass only a small fraction of the biomarker space for addiction, are incentive salience (see Glossary), negative emotionality, and executive function [2].”
From Addiction Biomarkers: Dimensional Approaches to Understanding Addiction (2018) · cites this paper as [2]
In the citing paper
“fourth, it is a research approach for assessment of addiction, not capable, or intended to diagnose DSM-based alcohol/substance use disorders.”
From Addiction Biomarkers: Dimensional Approaches to Understanding Addiction (2018) · cites this paper as [2]
In the citing paper
“first, it targets measures towards domains that are mechanistically important”
From Addiction Biomarkers: Dimensional Approaches to Understanding Addiction (2018) · cites this paper as [2]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90047-4 · Cited by 35,234
Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation
Beck, A. T., Steer, R. A., & Carbin, M. G. (1988) · Clinical Psychology Review · doi:10.1016/0272-7358(88)90050-5 · Cited by 11,696
The neural basis of drug craving: An incentive-sensitization theory of addiction
Robinson, T. (1993) · Brain Research Reviews · doi:10.1016/0165-0173(93)90013-p · Cited by 7,346
Insel, T., Cuthbert, B., Garvey, M., Heinssen, R., Pine, D. S., Quinn, K., Sanislow, C., & Wang, P. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.09091379 · Cited by 7,067
Development and validation of a brief screening version of the Childhood Trauma Questionnaire
Bernstein, D. P., Stein, J. A., Newcomb, M. D., Walker, E., Pogge, D., Ahluvalia, T., Stokes, J., Handelsman, L., Medrano, M., Desmond, D., et al. (2003) · Child Abuse & Neglect · doi:10.1016/s0145-2134(02)00541-0 · Cited by 6,419
A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1
Miki, Y., Swensen, J. J., Shattuck-Eidens, D. M., Futreal, P. A., Harshman, K., Tavtigian, S. V., Liu, Q., Cochran, C., Bennett, L. M., Ding, W., et al. (1994) · Science · doi:10.1126/science.7545954 · Cited by 6,069
Koob, G. F., & Volkow, N. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.110 · Cited by 5,340
Self-citationBagby, R. M., Parker, J. D. A., & Taylor, G. J. (1994) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(94)90005-1 · Cited by 5,293
The Fifth Edition of the Addiction Severity Index.
Mclellan, A., Kushner, H., Metzger, D., Peters, R., Smith, I. E., Grissom, G. R., Pettinati, H., & Argeriou, M. (1992) · Journal of Substance Abuse Treatment · doi:10.1016/0740-5472(92)90062-s · Cited by 4,280
N-back working memory paradigm: a meta-analysis of normative functional neuroimaging studies.
Owen, A. M., McMillan, K. M., Laird, A. R., & Bullmore, E. (2005) · Human Brain Mapping · doi:10.1002/hbm.20131 · Cited by 3,560
Bardo, M. T., & Hammer, R. P. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90226-e · Cited by 3,229
Toward the future of psychiatric diagnosis: the seven pillars of RDoC
Cuthbert, B. N., & Insel, T. R. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-126 · Cited by 3,053
Drug Addiction, Dysregulation of Reward, and Allostasis
Koob, G. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00195-0 · Cited by 2,953
Self-citationDysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications
Goldstein, R. Z., & Volkow, N. D. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3119 · Cited by 2,749 · cited 3×
“iRISA, as described by Goldstein and Volkow (33,41), identifies disruptions in neural circuits that relate to ADs, with an emphasis on response inhibition and salience attribution.”
BackgroundGoldstein, R. Z., & Volkow, N. D. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.10.1642 · Cited by 2,667
Grant, B. F., Goldstein, R. B., Saha, T. D., Chou, S. P., Jung, J., Zhang, H., Pickering, R. P., Ruan, W. J., Smith, S. M., Huang, B., et al. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2015.0584 · Cited by 2,556
Drug abuse: hedonic homeostatic dysregulation
Koob, G. F., & Moal, M. L. (1997) · Science · doi:10.1126/science.278.5335.52 · Cited by 2,535
Self-citationAnticipation of Increasing Monetary Reward Selectively Recruits Nucleus Accumbens
Knutson, B., Adams, C. M., Fong, G. W., & Hommer, D. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-16-j0002.2001 · Cited by 2,244
Neurogenetic Adaptive Mechanisms in Alcoholism
Cloninger, C. R. (1987) · Science · doi:10.1126/science.2882604 · Cited by 2,203
Vogel, C. L., Cobleigh, M. A., Tripathy, D., Gutheil, J. C., Harris, L. N., Fehrenbacher, L., Slamon, D. J., Murphy, M., Novotny, W. F., Burchmore, M., et al. (2002) · Journal of Clinical Oncology · doi:10.1200/jco.2002.20.3.719 · Cited by 1,860
Naltrexone in the Treatment of Alcohol Dependence
Volpicelli, J. R. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820110040006 · Cited by 1,828
A scale for the assessment of hedonic tone the Snaith-Hamilton pleasure scale
Snaith, R. P., Hamilton, M., Morley, S., Humayan, A., Hargreaves, D., & Trigwell, P. (1995) · British Journal of Psychiatry · doi:10.1192/bjp.167.1.99 · Cited by 1,778
The NIMH Research Domain Criteria (RDoC) Project: Precision Medicine for Psychiatry
Insel, T. R. (2014) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2014.14020138 · Cited by 1,472
Impulsivity and cigarette smoking: delay discounting in current, never, and ex-smokers
Bickel, W. K., Odum, A. L., & Madden, G. J. (1999) · Psychopharmacology · doi:10.1007/pl00005490 · Cited by 1,433
Evaluating stress : a book of resources
Zalaquett, C. P., & Wood, R. J. (1997) · Scarecrow Press eBooks · Cited by 1,176
Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction
Volkow, N. D., Wang, G.-J., Telang, F., Fowler, J. S., Logan, J., Childress, A.-R., Jayne, M., Ma, Y., & Wong, C. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1544-06.2006 · Cited by 1,164
Lobbestael, J., Leurgans, M., & Arntz, A. (2011) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.693 · Cited by 1,124
The genetics of addictions: uncovering the genes
Goldman, D., Oroszi, G., & Ducci, F. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1635 · Cited by 1,099
Self-citationCyberball: A program for use in research on interpersonal ostracism and acceptance
Williams, K. D., & Jarvis, B. (2006) · Behavior Research Methods · doi:10.3758/bf03192765 · Cited by 1,088
Lorains, F. K., Cowlishaw, S., & Thomas, S. A. (2011) · Addiction · doi:10.1111/j.1360-0443.2010.03300.x · Cited by 1,006
The Amygdala Response to Emotional Stimuli: A Comparison of Faces and Scenes
Hariri, A. R., Tessitore, A., Mattay, V. S., Fera, F., & Weinberger, D. R. (2002) · NeuroImage · doi:10.1006/nimg.2002.1179 · Cited by 984
Everitt, B. J., Belin, D., Economidou, D., Pelloux, Y., Dalley, J. W., & Robbins, T. W. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0089 · Cited by 974
Volkow, N. D., Chang, L., Wang, G.-J., Fowler, J. S., Ding, Y.-S., Sedler, M., Logan, J., Franceschi, D., Gatley, J., Hitzemann, R., et al. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.12.2015 · Cited by 916
The PhenX Toolkit: get the most from your measures
Hamilton, C. M., Strader, L. C., Pratt, J. G., Maiese, D., Hendershot, T., Kwok, R. K., Hammond, J. A., Huggins, W., Jackman, D., Pan, H., et al. (2011) · American Journal of Epidemiology · doi:10.1093/aje/kwr193 · Cited by 889
Conservatism in a simple probability inference task.
Phillips, L. D., & Edwards, W. (1966) · Journal of Experimental Psychology · doi:10.1037/h0023653 · Cited by 880
Dopamine neurons and their role in reward mechanisms
Schultz, W. (1997) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(97)80007-4 · Cited by 809
Petry, N. M. (2001) · Psychopharmacology · doi:10.1007/s002130000638 · Cited by 761
Anton, R. F., Moak, D. H., & Latham, P. K. (1995) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1995.tb01475.x · Cited by 679
The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology
Schumann, G., Loth, E., Banaschewski, T., Barbot, A., Barker, G. J., Büchel, C., Conrod, P., Dalley, J. W., Flor, H., Gallinat, J., et al. (2010) · Molecular Psychiatry · doi:10.1038/mp.2010.4 · Cited by 631
Dose-related neurocognitive effects of marijuana use
Bolla, K. I., Brown, K., Eldreth, D. A., Tate, K., & Cadet, J. L. (2002) · Neurology · doi:10.1212/01.wnl.0000031422.66442.49 · Cited by 609
Field, M., Munafò, M. R., & Franken, I. H. A. (2009) · Psychological Bulletin · doi:10.1037/a0015843 · Cited by 602
Kirschbaum, C., Klauer, T., Filipp, S., & Hellhammer, D. H. (1995) · Psychosomatic Medicine · doi:10.1097/00006842-199501000-00004 · Cited by 600
Gr�sser, S. M., Wrase, J., Klein, S., Hermann, D., Smolka, M. N., Ruf, M., Weber-Fahr, W., Flor, H., Mann, K., Braus, D. F., et al. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1828-4 · Cited by 598
A motivational view of learning, performance, and behavior modification.
Bindra, D. (1974) · Psychological Review · doi:10.1037/h0036330 · Cited by 594
Schacht, J. P., Anton, R. F., & Myrick, H. (2013) · Addiction Biology · doi:10.1111/j.1369-1600.2012.00464.x · Cited by 583
Matching Alcoholism Treatments to Client Heterogeneity: Project MATCH Three‐Year Drinking Outcomes
Project MATCH Research Group (1998) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1998.tb03912.x · Cited by 576
Slutske, W. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.2.297 · Cited by 554
Frontostriatal maturation predicts cognitive control failure to appetitive cues in adolescents
Somerville, L. H., Hare, T., & Casey, B. J. (2011) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2010.21572 · Cited by 523
Jasinska, A. J., Stein, E. A., Kaiser, J., Naumer, M. J., & Yalachkov, Y. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.10.013 · Cited by 513
Steer, R. A., & Beck, A. T. (1997) · Cited by 501
SINHA, R., & LI, C. ‐. R. (2007) · Drug and Alcohol Review · doi:10.1080/09595230601036960 · Cited by 497
Neurotransmitter roles in synaptic modulation, plasticity and learning in the dorsal striatum
Lovinger, D. M. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.01.008 · Cited by 488 · cited 1×
“The phasic dopaminergic activation that drives incentive salience is hypothesized to also engage habit formation and compulsive-like responding for addictive agents via activation of cortical-striatal-pallidal-thalamic loops (90,91).”
BackgroundAddiction as a stress surfeit disorder
Koob, G. F., Buck, C. L., Cohen, A., Edwards, S., Park, P. E., Schlosburg, J. E., Schmeichel, B., Vendruscolo, L. F., Wade, C. L., Whitfield, T. W., et al. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.05.024 · Cited by 483
Self-citationSinha, R., Fox, H. C., Hong, K. A., Bergquist, K., Bhagwagar, Z., & Siedlarz, K. M. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2008.78 · Cited by 466
Neuropsychosocial profiles of current and future adolescent alcohol misusers
Whelan, R., Watts, R., Orr, C., Althoff, R. R., Artiges, É., Banaschewski, T., Barker, G. J., Bokde, A. L. W., Büchel, C., Carvalho, F. M., et al. (2014) · Nature · doi:10.1038/nature13402 · Cited by 454
Anton, R. F., Oroszi, G., O’Malley, S., Couper, D., Swift, R., Pettinati, H., & Goldman, D. (2008) · Archives of General Psychiatry · doi:10.1001/archpsyc.65.2.135 · Cited by 451
Self-citationTower of london procedure: A standard method and developmental data
Krikorian, R., Bartok, J. A., & Gay, N. (1994) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/01688639408402697 · Cited by 449
The continuous performance test: a window on the neural substrates for attention?
Riccio, C. A., Reynolds, C. R., Lowe, P. A., & Moore, J. J. (2002) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/17.3.235 · Cited by 446
Profiles of Cognitive Dysfunction in Chronic Amphetamine and Heroin Abusers
Ornstein, T. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00097-x · Cited by 445
Assessing Anhedonia in Psychiatric Patients
FAWCETT, J. A. (1983) · Archives of General Psychiatry · doi:10.1001/archpsyc.1983.01790010081010 · Cited by 419
Subjective Responses to Alcohol in Sons of Alcoholics and Control Subjects
Schuckit, M. A. (1984) · Archives of General Psychiatry · doi:10.1001/archpsyc.1984.01790200061008 · Cited by 417
The Cold Pressor Test and Autonomic Function: A Review and Integration
Lovallo, W. (1975) · Psychophysiology · doi:10.1111/j.1469-8986.1975.tb01289.x · Cited by 409
Avoidance of emotional facial expressions in social anxiety: the approach-avoidance task
Heuer, K., Rinck, M., & Becker, E. S. (2007) · Behaviour Research and Therapy · doi:10.1016/j.brat.2007.08.010 · Cited by 380
A Neurodevelopmental Perspective on the Research Domain Criteria (RDoC) Framework
Casey, B. J., Oliveri, M. E., & Insel, T. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.01.006 · Cited by 369
Sinha, R. (2011) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.49 · Cited by 368
Matching Alcoholism Treatments to Client Heterogeneity
(1998) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-199809000-00016 · Cited by 362
Bickel, W. K., Jarmolowicz, D. P., Mueller, E. T., Gatchalian, K. M., & McClure, S. M. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2689-x · Cited by 338
The Role of Cognitive Control in Cocaine Dependence
Garavan, H., & Hester, R. (2007) · Neuropsychology Review · doi:10.1007/s11065-007-9034-x · Cited by 338
Heterogeneity of Alcohol Use Disorder: Understanding Mechanisms to Advance Personalized Treatment
Litten, R. Z., Ryan, M. L., Falk, D. E., Reilly, M., Fertig, J. B., & Koob, G. F. (2015) · Alcoholism: Clinical and Experimental Research · doi:10.1111/acer.12669 · Cited by 330
Self-citationProfile of Executive and Memory Function Associated with Amphetamine and Opiate Dependence
Ersche, K. D., Clark, L., London, M., Robbins, T. W., & Sahakian, B. J. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300889 · Cited by 311
A genetic determinant of the striatal dopamine response to alcohol in men
Ramchandani, V. A., Umhau, J. C., Pavón, F. J., Ruiz-Velasco, V., Margas, W., Sun, H., Damadzic, R., Eskay, R. L., Schoor, M., Thorsell, A., et al. (2010) · Molecular Psychiatry · doi:10.1038/mp.2010.56 · Cited by 298
Attentional bias predicts heroin relapse following treatment
Marissen, M. A. E., Franken, I. H. A., Waters, A. J., Blanken, P., van den Brink, W., & Hendriks, V. M. (2006) · Addiction · doi:10.1111/j.1360-0443.2006.01498.x · Cited by 286
Carter, C. S., & Barch, D. M. (2007) · Schizophrenia Bulletin · doi:10.1093/schbul/sbm081 · Cited by 278
Ehrman, R. N., Robbins, S. J., Bromwell, M. A., Lankford, M. E., Monterosso, J. R., & O’Brien, C. P. (2002) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(02)00065-0 · Cited by 271
Moderate drug use and delay discounting: A comparison of heavy, light, and never smokers.
Johnson, M. W., Bickel, W. K., & Baker, F. (2007) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.15.2.187 · Cited by 259
Pharmacogenetic approaches to the treatment of alcohol addiction
Heilig, M. A., Goldman, D. A., Berrettini, W. H., & O’Brien, C. P. (2011) · Nature reviews. Neuroscience · doi:10.1038/nrn3110 · Cited by 256
Self-citationNaltrexone-induced alterations in human ethanol intoxication
(1994) · American Journal of Psychiatry · doi:10.1176/ajp.151.10.1463 · Cited by 254
Alcohol and opioid dependence medications: Prescription trends, overall and by physician specialty
Mark, T. L., Kassed, C. A., Vandivort-Warren, R., Levit, K. R., & Kranzler, H. R. (2008) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2008.07.018 · Cited by 246
Anhedonia and Substance Dependence: Clinical Correlates and Treatment Options
Hatzigiakoumis, D. S., Martinotti, G., Giannantonio, M. D., & Janiri, L. (2011) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2011.00010 · Cited by 245
Relationship between reward-enhancing and stereotypical effects of psychomotor stimulant drugs
ROBBINS, T. W. (1976) · Nature · doi:10.1038/264057a0 · Cited by 241
Dose-Related Neurobehavioral Effects of Chronic Cocaine Use
Bolla, K. I., Rothman, R. B., & Cadet, J. L. (1999) · Journal of Neuropsychiatry · doi:10.1176/jnp.11.3.361 · Cited by 214
Neuroprotective and Abstinence-Promoting Effects of Acamprosate: Elucidating the Mechanism of Action
De Witte, P., Littleton, J., Parot, P., & Koob, G. (2005) · CNS Drugs · doi:10.2165/00023210-200519060-00004 · Cited by 201
Self-citationThe inventory of socially supportive behaviors: Dimensionality, prediction, and gender differences
Stokes, J. P., & Wilson, D. G. (1984) · American Journal of Community Psychology · doi:10.1007/bf00896928 · Cited by 201
Typologies of Alcohol Dependence. From Jellinek to Genetics and Beyond
Leggio, L., Kenna, G. A., Fenton, M. C., Bonenfant, E., & Swift, R. M. (2009) · Neuropsychology Review · doi:10.1007/s11065-008-9080-z · Cited by 200
Nelson, C. B., Rehm, J. T., Bedirhan, T., Grant, B. F., & Chatterji, S. (1999) · Addiction · doi:10.1046/j.1360-0443.1999.9468438.x · Cited by 197
Filbey, F. M., Ray, L. A., Smolen, A., Claus, E. D., Audette, A., & Hutchison, K. E. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00692.x · Cited by 195
Model-Based and Model-Free Decisions in Alcohol Dependence
Sebold, M., Deserno, L., Nebe, S., Schad, D. J., Garbusow, M., Hägele, C., Keller, J., Jünger, E., Kathmann, N., Smolka, M. N., et al. (2014) · Neuropsychobiology · doi:10.1159/000362840 · Cited by 193
Working memory deficits predict short-term smoking resumption following brief abstinence
Patterson, F., Jepson, C., Loughead, J., Perkins, K. A., Strasser, A. A., Siegel, S. J., Frey, J. M., Gur, R. C., & Lerman, C. E. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.07.020 · Cited by 190
The continuous performance test: a window on the neural substrates for attention?
Riccio, C. A. (2002) · Archives of Clinical Neuropsychology · doi:10.1016/s0887-6177(01)00111-1 · Cited by 178
A genetically modulated, intrinsic cingulate circuit supports human nicotine addiction
Hong, L. E., Hodgkinson, C. A., Yang, Y., Sampath, H., Ross, T. J., Buchholz, B., Salmeron, B. J., Srivastava, V., Thaker, G. K., Goldman, D. A., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1004745107 · Cited by 169
Self-citationDrugs and addiction: an introduction to epigenetics
Wong, C. C. Y., Mill, J. S., & Fernandes, C. (2010) · Addiction · doi:10.1111/j.1360-0443.2010.03321.x · Cited by 166
Salo, R. E., Ursu, S., Buonocore, M. H., Leamon, M. H., & Carter, C. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.11.026 · Cited by 160
Zhu, X., Cortes, C. R., Mathur, K., Tomasi, D. G., & Momenan, R. (2015) · Addiction Biology · doi:10.1111/adb.12272 · Cited by 159
Self-citationVollstädt‐Klein, S., Loeber, S., Richter, A., Kirsch, M., Bach, P., von der Goltz, C., Hermann, D., Mann, K. F., & Kiefer, F. (2011) · Addiction Biology · doi:10.1111/j.1369-1600.2011.00352.x · Cited by 158
Janiri, L., Martinotti, G., Dario, T., Reina, D., Paparello, F., Pozzi, G., Addolorato, G., Giannantonio, M. D., & Risio, S. D. (2005) · Neuropsychobiology · doi:10.1159/000086176 · Cited by 150
Adolescent Substance Abuse: The Effects of Alcohol and Marijuana on Neuropsychological Performance
Thoma, R. J., Monnig, M. A., Lysne, P. A., Ruhl, D. A., Pommy, J. A., Bogenschutz, M. P., Tonigan, J. S., & Yeo, R. A. (2010) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2010.01320.x · Cited by 149
Alcohol Protracted Withdrawal Syndrome: The Role of Anhedonia
Martinotti, G., Nicola, M. D., Reina, D., Andreoli, S., Focà, F., Cunniff, A. L., Tonioni, F., Bria, P., & Janiri, L. (2008) · Substance Use & Misuse · doi:10.1080/10826080701202429 · Cited by 142
CNTRICS Final Task Selection: Social Cognitive and Affective Neuroscience-Based Measures
Carter, C. S., Barch, D. M., Gur, R. E., Gur, R. E., Pinkham, A. E., & Ochsner, K. N. (2008) · Schizophrenia Bulletin · doi:10.1093/schbul/sbn157 · Cited by 139
Anhedonia in Schizophrenic, Depressed, or Alcohol-Dependent Patients - Neurobiological Correlates
Heinz, A., Schmidt, L., & Reischies, F. M. (1994) · Pharmacopsychiatry · doi:10.1055/s-2007-1014317 · Cited by 130
Subtypes of cocaine abusers: Support for a Type A-Type B distinction.
Ball, S. A., Carroll, K. M., Babor, T. F., & Rounsaville, B. J. (1995) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.63.1.115 · Cited by 130
CNTRICS Final Task Selection: Working Memory
Barch, D. M., Berman, M. G., Engle, R. F., Jones, J. H., Jonides, J., MacDonald, A. W., Nee, D. E., Redick, T. S., & Sponheim, S. R. (2008) · Schizophrenia Bulletin · doi:10.1093/schbul/sbn153 · Cited by 124
Naltrexone vs Placebo for the Treatment of Alcohol Dependence
Oslin, D. W., Leong, S. H., Lynch, K. G., Berrettini, W. H., O’Brien, C. P., Gordon, A. J., & Rukstalis, M. R. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.3053 · Cited by 121
Heilig, M., Thorsell, A., Sommer, W. H., Hansson, A. C., Ramchandani, V. A., George, D. T., Hommer, D., & Barr, C. S. (2010) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.11.018 · Cited by 117
The impact of heroin on frontal executive functions
Pau, C. W. H., Lee, T. M. C., & Chan, S.-F. F. (2002) · Archives of Clinical Neuropsychology · doi:10.1016/s0887-6177(01)00169-x · Cited by 117
Alcoholism, a genus and some of its species.
JELLINEK, E. M. (1960) · PubMed · Cited by 114
Drug abstinence and cognitive control in methamphetamine-dependent individuals
Salo, R., Nordahl, T. E., Galloway, G. P., Moore, C. D., Waters, C., & Leamon, M. H. (2009) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2009.03.004 · Cited by 109
Enhanced Choice for Viewing Cocaine Pictures in Cocaine Addiction
Moeller, S. J., Maloney, T., Parvaz, M. A., Dunning, J. P., Alia‐Klein, N., Woicik, P. A., Hajcak, G., Telang, F., Wang, G., Volkow, N. D., et al. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.02.015 · Cited by 108
Acamprosate and alcohol: II. Effects on alcohol withdrawal in the rat
Spanagel, R., Putzke, J., Stefferl, A., Schöbitz, B., & Zieglgänsberger, W. (1996) · European Journal of Pharmacology · doi:10.1016/0014-2999(96)00175-6 · Cited by 100
Executive Functions in Pathologic Gamblers Selected in an Ecologic Setting
Roca, M., Torralva, T., López, P. L., Cetkovich, M., Clark, L., & Manes, F. F. (2008) · Cognitive and Behavioral Neurology · doi:10.1097/wnn.0b013e3181684358 · Cited by 89
Typology of club drug use among young adults recruited using time–space sampling
Ramo, D. E., Grov, C., Delucchi, K., Kelly, B. C., & Parsons, J. T. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.09.014 · Cited by 87
The Pharmacogenetics of Alcohol Use Disorder
Jones, J. D., Comer, S. D., & Kranzler, H. R. (2015) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12643 · Cited by 81
CNTRICS Imaging Biomarkers Selection: Working Memory
Barch, D. M., Moore, H. M., Nee, D. E., Manoach, D. S., & Luck, S. J. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr160 · Cited by 76
Loeber, S., & Duka, T. (2009) · Addiction · doi:10.1111/j.1360-0443.2009.02718.x · Cited by 75
Why do young women smoke? III. Attention and impulsivity as neurocognitive predisposing factors☆
Yakir, A., Rigbi, A., Kanyas, K., Pollak, Y., KAHANA, G., Karni, O., Eitan, R., Kertzman, S., & Lerer, B. (2006) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2006.09.004 · Cited by 75
Role of GABRA2 in Moderating Subjective Responses to Alcohol
Roh, S., Matsushita, S., Hara, S., Maesato, H., Matsui, T., Suzuki, G., Miyakawa, T., Ramchandani, V. A., Li, T., & Higuchi, S. (2010) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2010.01357.x · Cited by 68
Loth, E., Poline, J.-B., Thyreau, B., Jia, T., Tao, C., Lourdusamy, A., Stacey, D., Cattrell, A., Desrivières, S., Ruggeri, B., et al. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.07.043 · Cited by 65
Gilman, J. M., Smith, A. R., Ramchandani, V. A., Momenan, R., & Hommer, D. W. (2011) · Addiction Biology · doi:10.1111/j.1369-1600.2011.00383.x · Cited by 59
Self-citationFrom Symptoms to Neurobiology: Pathological Gambling in the Light of the New Classification in DSM-5
Romanczuk‐Seiferth, N., van den Brink, W., & Goudriaan, A. E. (2014) · Neuropsychobiology · doi:10.1159/000362839 · Cited by 57
IMAGEN consortium, Tzschoppe, J., Nees, F., Banaschewski, T., Barker, G. J., Büchel, C., Conrod, P. J., Garavan, H., Heinz, A., Loth, E., et al. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2013.287 · Cited by 49
Crack cocaine trajectories among users in a midwestern American city
Falck, R. S., Wang, J., & Carlson, R. G. (2007) · Addiction · doi:10.1111/j.1360-0443.2007.01915.x · Cited by 49
Babor, T. F., Webb, C. P. M., Burleson, J. A., & Kaminer, Y. (2002) · Addiction · doi:10.1046/j.1360-0443.97.s1.1.x · Cited by 44
Data Compatibility in the Addiction Sciences: An Examination of Measure Commonality
Conway, K., Vullo, G. C., Kennedy, A. P., Finger, M. S., Agrawal, A., Bjork, J., Farrer, L., Hancock, D. B., Hussong, A., Wakim, P. G., et al. (2014) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2014.04.029 · Cited by 44
Müller, K. U., Gan, G., Banaschewski, T., Barker, G. J., Bokde, A. L. W., Büchel, C., Conrod, P., Fauth‐Bühler, M., Flor, H., Gallinat, J., et al. (2014) · Addiction Biology · doi:10.1111/adb.12136 · Cited by 43
Improved methods to identify stable, highly heritable subtypes of opioid use and related behaviors
Sun, J., Bi, J., Chan, G., Oslin, D. W., Farrer, L. A., Gelernter, J. E., & Kranzler, H. R. (2012) · Addictive Behaviors · doi:10.1016/j.addbeh.2012.05.010 · Cited by 43
A dissociation in attentional control: Evidence from methamphetamine dependence
Salo, R. E., NORDAHL, T. E., Moore, C. D., Waters, C., Natsuaki, Y., Galloway, G. P., Kile, S. J., & Sullivan, E. V. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.10.035 · Cited by 41
Thyreau, B., Schwartz, Y., Thirion, B., Frouin, V., Loth, E., Vollstädt‐Klein, S., Paus, T., Eric Artiges, A., Conrod, P., Schumann, G., et al. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.02.083 · Cited by 41
Midbrain-Driven Emotion and Reward Processing in Alcoholism
Müller-Oehring, E. M., Jung, Y.-C., Sullivan, E. V., Hawkes, W. C., Pfefferbaum, A., & Schulte, T. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.102 · Cited by 38 · cited 1×
“With respect to measures of various components of incentive salience, the neural responses of addicted individuals are altered to both cue and non-cue targets (78-80), with increased craving for substances in response to related cues (81, 82), and differences in reward learning (83).”
BackgroundScott, L. J., Figgitt, D. P., Keam, S. J., & Waugh, J. (2005) · CNS Drugs · doi:10.2165/00023210-200519050-00006 · Cited by 37
Wïttchen, H., Behrendt, S., Höfler, M., Perkonigg, A., Rehm, J. T., Lieb, R., & Beesdo‐Baum, K. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.02.012 · Cited by 36
Nymberg, C., Banaschewski, T., Bokde, A. L. W., Büchel, C., Conrod, P., Flor, H., Frouin, V., Garavan, H., Gowland, P. A., Heinz, A., et al. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.83 · Cited by 34
Resting‐state functional connectivity and presynaptic monoamine signaling in Alcohol Dependence
Zhu, X., Dutta, N., Helton, S. G., Schwandt, M. L., Yan, J., Hodgkinson, C. A., Cortes, C. R., Kerich, M., Hall, S. D., Sun, H., et al. (2015) · Human Brain Mapping · doi:10.1002/hbm.22951 · Cited by 33
Self-citationBehavioral therapy across the spectrum.
Witkiewitz, K. A., & Marlatt, A. G. (2011) · Europe PMC (PubMed Central) · Cited by 32
A Pilot Study of Neurocognitive Function in Older and Younger Cocaine Abusers and Controls
Kalapatapu, R. K., Vadhan, N. P., Rubin, E., Bedi, G., Cheng, W. Y., Sullivan, M. A., & Foltin, R. W. (2011) · American Journal on Addictions · doi:10.1111/j.1521-0391.2011.00128.x · Cited by 31
Using PhenX measures to identify opportunities for cross-study analysis
Pan, H. H., Tryka, K. A., Vreeman, D. J., Huggins, W., Phillips, M. J., Mehta, J. P., Phillips, J. H., McDonald, C. J., Junkins, H., Ramos, E. M., et al. (2012) · Human Mutation · doi:10.1002/humu.22074 · Cited by 30
PhenX RISING: real world implementation and sharing of PhenX measures
McCarty, C., Huggins, W., Aiello, A., Bilder, R., Hariri, A., Jernigan, T., Newman, E., Sanghera, D., Strauman, T. J., Zeng, Y., et al. (2014) · BMC Medical Genomics · doi:10.1186/1755-8794-7-16 · Cited by 29
Effects of Naltrexone During the Descending Limb of the Blood Alcohol Curve
Ray, L. A., Hutchison, K. E., MacKillop, J. M., Miranda, R., Audette, A., Swift, R. M., & Monti, P. M. (2008) · American Journal on Addictions · doi:10.1080/10550490802138400 · Cited by 28
CNTRICS Imaging Biomarkers Final Task Selection: Long-Term Memory and Reinforcement Learning
Ragland, J. D., Cohen, N. J., Cools, R., Frank, M., Hannula, D. E., & Ranganath, C. (2011) · Schizophrenia Bulletin · doi:10.1093/schbul/sbr168 · Cited by 27
Using the PhenX Toolkit to Add Standard Measures to a Study
Hendershot, T., Pan, H., Haines, J., Harlan, W. R., Marazita, M. L., McCarty, C. A., Ramos, E. M., & Hamilton, C. M. (2015) · Current Protocols in Human Genetics · doi:10.1002/0471142905.hg0121s86 · Cited by 25
Analytical strategies for large imaging genetic datasets: experiences from the IMAGEN study
Nymberg, C., Jia, T., Ruggeri, B., & Schumann, G. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12088 · Cited by 25
Brooks, P. J., Goldman, D. A., & Li, T. (2009) · Human Genomics · doi:10.1186/1479-7364-3-2-103 · Cited by 20
Self-citationMcCarty, C. A., Berg, R. L., Rottscheit, C., Waudby, C. J., Kitchner, T., Brilliant, M. H., & Ritchie, M. D. (2014) · BMC Medical Genomics · doi:10.1186/1755-8794-7-3 · Cited by 16
RDoC and DSM-5: What's the Fuss?
Carpenter, W. T. (2013) · Schizophrenia Bulletin · doi:10.1093/schbul/sbt101 · Cited by 13
Jokisch, D., Roser, P., Juckel, G., Daum, I., & Bellebaum, C. (2014) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.12460 · Cited by 12
Using the PhenX Toolkit to Add Standard Measures to a Study
Hendershot, T. P., Pan, H. H., Haines, J. L., Harlan, W. R., Junkins, H., Ramos, E. M., & Hamilton, C. M. (2011) · Current Protocols in Human Genetics · doi:10.1002/0471142905.hg0121s71 · Cited by 12
Hitz, M. M., Conway, P., Palcher, J. A., & McCarty, C. A. (2014) · BMC Research Notes · doi:10.1186/1756-0500-7-847 · Cited by 9
Factor structure of the Barratt impulsiveness scale
Patton, J. H., Stanford, M. S., & Barratt, E. S. (1995) · Journal of Clinical Psychology · doi:10.1002/1097-4679(199511)51:6
Cited by
Sorted by citations
Neurobiology of addiction: a neurocircuitry analysis
Koob, G. F., & Volkow, N. D. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(16)00104-8 · Cited by 3,698
Self-citationKotov, R., Krueger, R. F., Watson, D., Cicero, D. C., Conway, C. C., DeYoung, C. G., Eaton, N. R., Forbes, M. K., Hallquist, M. N., Latzman, R. D., et al. (2021) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-081219-093304 · Cited by 596
Advances in the science and treatment of alcohol use disorder
Witkiewitz, K. A., Litten, R. Z., & Leggio, L. (2019) · Science Advances · doi:10.1126/sciadv.aax4043 · Cited by 629
Self-citationDrug Addiction: Hyperkatifeia/Negative Reinforcement as a Framework for Medications Development
Koob, G. F. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000083 · Cited by 337
Self-citation
Metadata
- Authors
- Kwako, L. E., Momenan, R., Litten, R. Z., Koob, G. F., & Goldman, D.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Kwako, Laura E.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2016-08
- Volume
- 80
- Issue
- 3
- Pages
- 179-189
- ISSN
- 0006-3223 (ISSN-L)
- PMC
- PMC4870153
- OpenAlex
- W2207035985
- Semantic Scholar
- 621a35dbbd45d7e898e2999389a1fe6c88ac4688
- Cited by
- 395
- References
- 151
- Citations by year
- 2026: 48 · 2025: 32 · 2024: 46 · 2023: 38 · 2022: 43 · 2021: 47 · 2020: 38 · 2019: 46 · 2018: 24 · 2017: 27 · 2016: 6
- FWCI
- 2.47
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (Z99‐AA999999)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Keywords
- addiction, executive function, incentive salience, negative affectivity, addiction classification, Research Domain Criteria, neuroimaging, clinical heterogeneity, causes of addiction
- MeSH terms
- Emotions, Humans, Models, Psychological, Motivation, Neuropsychological Tests, Behavior, Addictive, Substance-Related Disorders, Executive Function, Neuroimaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
