Kisspeptin Neurons in the Arcuate Nucleus of the Hypothalamus Orchestrate Circadian Rhythms and Metabolism

Obesity and Metabolic Syndrome in Circadian <i>Clock</i> Mutant Mice

Turek, F. W., Joshu, C., Kohsaka, A., Lin, E., Ivanova, G., McDearmon, E., Laposky, A., Losee-Olson, S., Easton, A., Jensen, D. R., et al. (2005) · Science · doi:10.1126/science.1108750 · Cited by 2,485 · see citing works

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

Yoo, S.-H., Yamazaki, S., Lowrey, P. L., Shimomura, K., Ko, C. H., Buhr, E. D., Siepka, S. M., Hong, H.-K., Oh, W. J., Yoo, O. J., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308709101 · Cited by 2,329 · see citing works

Central and Peripheral Circadian Clocks in Mammals

Mohawk, J. A., Green, C. B., & Takahashi, J. S. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153128 · Cited by 2,265 · see citing works

Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

Hatori, M., Vollmers, C., Zarrinpar, A., DiTacchio, L., Bushong, E. A., Gill, S., Leblanc, M., Chaix, A., Joens, M., Fitzpatrick, J. A. J., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.04.019 · Cited by 1,986 · see citing works

Dynamics of gonadotropin-releasing hormone release during a pulse.

Moenter, S. M., Brand, R. M., MIDGLEY, A. R., & Karsch, F. J. (1992) · Endocrinology · doi:10.1210/endo.130.1.1727719 · Cited by 1,257 · see citing works

NPY/AgRP Neurons Are Essential for Feeding in Adult Mice but Can Be Ablated in Neonates

Luquet, S. H., Perez, F. A., Hnasko, T. S., & Palmiter, R. D. (2005) · Science · doi:10.1126/science.1115524 · Cited by 1,127 · see citing works

Physiology of Circadian Entrainment

Golombek, D. A., & Rosenstein, R. E. (2010) · Physiological Reviews · doi:10.1152/physrev.00009.2009 · Cited by 1,103 · see citing works

Regulation of Kiss1 gene expression in the brain of the female mouse

Smith, J. T., Cunningham, M. J., Rissman, E. F., Clifton, D. K., & Steiner, R. A. (2005) · Endocrinology · doi:10.1210/en.2005-0488 · Cited by 1,102 · see citing works

Generation of circadian rhythms in the suprachiasmatic nucleus

Hastings, M. H., Maywood, E. S., & Brancaccio, M. (2018) · Nature Reviews Neuroscience · doi:10.1038/s41583-018-0026-z · Cited by 1,065 · see citing works

Light as a central modulator of circadian rhythms, sleep and affect

LeGates, T. A., Fernandez, D. C., & Hattar, S. (2014) · Nature Reviews Neuroscience · doi:10.1038/nrn3743 · Cited by 1,001 · see citing works

Circadian timing of food intake contributes to weight gain

Arble, D. M., Bass, J., Laposky, A. D., Vitaterna, M. H., & Turek, F. W. (2009) · Obesity · doi:10.1038/oby.2009.264 · Cited by 953 · see citing works

Temperature as a Universal Resetting Cue for Mammalian Circadian Oscillators

Buhr, E. D., Yoo, S.-H., & Takahashi, J. S. (2010) · Science · doi:10.1126/science.1195262 · Cited by 917 · see citing works

Diurnal transcriptome atlas of a primate across major neural and peripheral tissues

Mure, L. S., Le, H. D., Benegiamo, G., Chang, M. W., Ríos, L., Jillani, N., Ngotho, M., Kariuki, T., Dkhissi‐Benyahya, O., Cooper, H. M., et al. (2018) · Science · doi:10.1126/science.aao0318 · Cited by 783 · see citing works

Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse

Navarro, V. M., Gottsch, M. L., Chavkin, C., Okamura, H., Clifton, D. K., & Steiner, R. A. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1569-09.2009 · Cited by 779 · see citing works

Differential Regulation of KiSS-1 mRNA Expression by Sex Steroids in the Brain of the Male Mouse

Smith, J. T., Lemko, H. M. D., Stoll, E. A., Gottsch, M. L., Braun, R. E., Eacker, S. M., Clifton, D. K., & Steiner, R. A. (2005) · Endocrinology · doi:10.1210/en.2005-0323 · Cited by 694 · see citing works

Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B

Goodman, R. L., Lehman, M. N., Smith, J. T., Coolen, L. M., de Oliveira, C. V. R., Jafarzadehshirazi, M. R., Pereira, A., Iqbal, J., Caraty, A., Ciofi, P., et al. (2007) · Endocrinology · doi:10.1210/en.2007-0961 · Cited by 692 · see citing works

Circadian rhythms in isolated brain regions

Abe, M., Herzog, E. D., Yamazaki, S., Straume, M., Tei, H., Sakaki, Y., Menaker, M., & Block, G. D. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00350.2002 · Cited by 681 · see citing works

Efferent projections of the suprachiasmatic nucleus: I. Studies using anterograde transport of Phaseolus vulgaris leucoagglutinin in the rat

Watts, A. G., Swanson, L. W., & Sanchez‐Watts, G. (1987) · The Journal of Comparative Neurology · doi:10.1002/cne.902580204 · Cited by 678 · see citing works

Autistic-like behaviour in Scn1a+/− mice and rescue by enhanced GABA-mediated neurotransmission

Han, S., Tai, C., Westenbroek, R. E., Yu, F. H., Cheah, C. S., Potter, G. B., Rubenstein, J. L., Scheuer, T., de la Iglesia, H. O., & Catterall, W. A. (2012) · Nature · doi:10.1038/nature11356 · Cited by 643 · see citing works

Sex differences in sleep: impact of biological sex and sex steroids

Mong, J. A., & Cusmano, D. M. (2016) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2015.0110 · Cited by 578 · see citing works

Meal frequency and timing in health and disease

Mattson, M. P., Allison, D. B., Fontana, L., Harvie, M., Longo, V. D., Malaisse, W. J., Mosley, M., Notterpek, L. M., Ravussin, É., Scheer, F. A. J. L., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1413965111 · Cited by 533 · see citing works

The hypothalamic integrator for circadian rhythms

Saper, C. B., Lü, J., Chou, T. C., & Gooley, J. J. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2004.12.009 · Cited by 528 · see citing works

Elucidating an Affective Pain Circuit that Creates a Threat Memory

Han, S., Soleiman, M. T., Soden, M. E., Zweifel, L. S., & Palmiter, R. D. (2015) · Cell · doi:10.1016/j.cell.2015.05.057 · Cited by 447 · see citing works

Kisspeptin–GPR54 Signaling Is Essential for Preovulatory Gonadotropin-Releasing Hormone Neuron Activation and the Luteinizing Hormone Surge

Clarkson, J., d'Anglemont de Tassigny, X., Moreno, A. S., Colledge, W. H., & Herbison, A. E. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1775-08.2008 · Cited by 436 · see citing works

Spontaneous Neural Activity Is Required for the Establishment and Maintenance of the Olfactory Sensory Map

Yu, C., Power, J., Barnea, G., O'Donnell, S., Brown, H. E. V., Osborne, J., Axel, R., & Gogos, J. A. (2004) · Neuron · doi:10.1016/s0896-6273(04)00224-7 · Cited by 392 · see citing works

Definition of the hypothalamic GnRH pulse generator in mice

Clarkson, J., Han, S. Y., Piet, R., McLennan, T., Kane, G. M., Ng, J., Porteous, R. W., Kim, J. S., Colledge, W. H., Iremonger, K. J., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1713897114 · Cited by 392 · see citing works

Characterization of Kiss1 neurons using transgenic mouse models

Cravo, R. M., Margatho, L. O., Osborne-Lawrence, S., Donato, J., Atkin, S., Bookout, A. L., Rovinsky, S., Frazão, R., Lee, C. E., Gautron, L., et al. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2010.11.022 · Cited by 353 · see citing works

Estradiol shortens the period of hamster circadian rhythms

Morin, L. P., Fitzgerald, K. M., & Zucker, I. (1977) · Science · doi:10.1126/science.557840 · Cited by 350 · see citing works

Contrasting Effects of Ibotenate Lesions of the Paraventricular Nucleus and Subparaventricular Zone on Sleep–Wake Cycle and Temperature Regulation

Lu, J., Zhang, Y.-H., Chou, T. C., Gaus, S. E., Elmquist, J. K., Shiromani, P. J., & Saper, C. B. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-13-04864.2001 · Cited by 335 · see citing works

A Daily Signal for the LH Surge in the Rat

Legan, S. J., & Karsch, F. J. (1975) · Endocrinology · doi:10.1210/endo-96-1-57 · Cited by 333 · see citing works

Sleep and the sleep electroencephalogram across the menstrual cycle in young healthy women

Driver, H. S. (1996) · Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.81.2.728 · Cited by 314 · see citing works

Meta‐analysis on night shift work and risk of metabolic syndrome

Wang, F., Zhang, L., Zhang, Y., Zhang, B., He, Y., Xie, S., Li, M., Miao, X., Chan, E. Y. Y., Tang, J. L., et al. (2014) · Obesity Reviews · doi:10.1111/obr.12194 · Cited by 302 · see citing works

Coexpression of dynorphin and neurokinin B immunoreactivity in the rat hypothalamus: morphologic evidence of interrelated function within the arcuate nucleus

Burke, M. C., Letts, P. A., Krajewski, S. J., & Rance, N. E. (2006) · Journal of Comparative Neurology · doi:10.1002/cne.21086 · Cited by 280 · see citing works

Estrogen Increases Locomotor Activity in Mice through Estrogen Receptor α: Specificity for the Type of Activity

Ogawa, S., Chan, J., Gustafsson, J.-A., Korach, K. S., & Pfaff, D. W. (2003) · Endocrinology · doi:10.1210/en.2002-220519 · Cited by 275 · see citing works

Parabrachial CGRP Neurons Control Meal Termination

Campos, C. A., Bowen, A. J., Schwartz, M. W., & Palmiter, R. D. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.04.006 · Cited by 262 · see citing works

Mice under Caloric Restriction Self-Impose a Temporal Restriction of Food Intake as Revealed by an Automated Feeder System

Acosta-Rodríguez, V. A., de Groot, M. H. M., Rijo‐Ferreira, F., Green, C. B., & Takahashi, J. S. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2017.06.007 · Cited by 252 · see citing works

Kisspeptin Directly Excites Anorexigenic Proopiomelanocortin Neurons but Inhibits Orexigenic Neuropeptide Y Cells by an Indirect Synaptic Mechanism

Fu, L.-Y., & van den Pol, A. N. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.2098-10.2010 · Cited by 243 · see citing works

Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factorPreprint

Reinke, H., Saini, C., Fleury-Olela, F., Dibner, C., Benjamin, I. J., & Schibler, U. (2008) · Genes & Development · doi:10.1101/gad.453808 · Cited by 228 · see citing works

AgRP to Kiss1 neuron signaling links nutritional state and fertility

Padilla, S. L., Qiu, J., Nestor, C. C., Zhang, C., Smith, A. W., Whiddon, B. B., Rønnekleiv, O. K., Kelly, M. J., & Palmiter, R. D. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1621065114 · Cited by 225 · see citing works

Female reproductive maturation in the absence of kisspeptin/GPR54 signaling

Mayer, C., & Boehm, U. (2011) · Nature Neuroscience · doi:10.1038/nn.2818 · Cited by 213 · see citing works

Role for kisspeptin/neurokinin B/dynorphin (KNDy) neurons in cutaneous vasodilatation and the estrogen modulation of body temperature

Mittelman‐Smith, M. A., Williams, H., Krajewski, S. J., McMullen, N. T., & Rance, N. E. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1211517109 · Cited by 208 · see citing works

High-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neurons

Qiu, J., Nestor, C. C., Zhang, C., Padilla, S. L., Palmiter, R. D., Kelly, M. J., & Rønnekleiv, O. K. (2016) · eLife · doi:10.7554/elife.16246 · Cited by 199 · see citing works

Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity

Tolson, K. P., Garcia, C. K., Yen, S., Simonds, S. E., Stefanidis, A., Lawrence, A. R., Smith, J. T., & Kauffman, A. S. (2014) · Journal of Clinical Investigation · doi:10.1172/jci71075 · Cited by 194 · see citing works

Arcuate Kisspeptin/Neurokinin B/Dynorphin (KNDy) Neurons Mediate the Estrogen Suppression of Gonadotropin Secretion and Body Weight

Mittelman‐Smith, M. A., Williams, H., Krajewski, S. J., Lai, J. Y., Ciofi, P., McMullen, N. T., & Rance, N. E. (2012) · Endocrinology · doi:10.1210/en.2012-1045 · Cited by 189 · see citing works

Selective optogenetic activation of arcuate kisspeptin neurons generates pulsatile luteinizing hormone secretion

Han, S. Y., McLennan, T., Czieselsky, K., & Herbison, A. E. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1512243112 · Cited by 189 · see citing works

Circadian Control of Kisspeptin and a Gated GnRH Response Mediate the Preovulatory Luteinizing Hormone Surge

Williams, W. P., Jarjisian, S. G., Mikkelsen, J. D., & Kriegsfeld, L. J. (2011) · Endocrinology · doi:10.1210/en.2010-0943 · Cited by 181 · see citing works

Projections of Arcuate Nucleus and Rostral Periventricular Kisspeptin Neurons in the Adult Female Mouse Brain

Yeo, S., & Herbison, A. E. (2011) · Endocrinology · doi:10.1210/en.2011-0164 · Cited by 174 · see citing works

The Suprachiasmatic Nucleus Controls Circadian Energy Metabolism and Hepatic Insulin Sensitivity

Coomans, C. P., van den Berg, S. A. A., Lucassen, E. A., Houben, T., Pronk, A. C. M., van der Spek, R. D., Kalsbeek, A., Biermasz, N. R., Willems van Dijk, K., Romijn, J. A., et al. (2013) · Diabetes · doi:10.2337/db12-0507 · Cited by 173 · see citing works

A riot of rhythms: neuronal and glial circadian oscillators in the mediobasal hypothalamus

Guilding, C., Hughes, A. T. L., Brown, T. M., Namvar, S., & Piggins, H. D. (2009) · Molecular Brain · doi:10.1186/1756-6606-2-28 · Cited by 171 · see citing works

Sleep and Eating Disorders

Allison, K. C., Spaeth, A. M., & Hopkins, C. M. (2016) · Current Psychiatry Reports · doi:10.1007/s11920-016-0728-8 · Cited by 171 · see citing works

A Neural Circuit Underlying the Generation of Hot Flushes

Padilla, S. L., Johnson, C. W., Barker, F. D., Patterson, M. A., & Palmiter, R. D. (2018) · Cell Reports · doi:10.1016/j.celrep.2018.06.037 · Cited by 166 · see citing works

Cancer-induced anorexia and malaise are mediated by CGRP neurons in the parabrachial nucleus

Campos, C., Bowen, A. J., Han, S., Wisse, B. E., Palmiter, R. D., & Schwartz, M. W. (2017) · Nature Neuroscience · doi:10.1038/nn.4574 · Cited by 146 · see citing works

Sex- and age-specific differences in core body temperature of C57Bl/6 mice

Sanchez-Alavez, M., Alboni, S., & Conti, B. (2011) · AGE · doi:10.1007/s11357-010-9164-6 · Cited by 140 · see citing works

Identification of Neurokinin B-Expressing Neurons as an Highly Estrogen-Receptive, Sexually Dimorphic Cell Group in the Ovine Arcuate Nucleus**This work was supported by the United Kingdom Biotechnology and Biological Sciences Research Council (to J.E.R. and A.E.H.) and a European Community Marie Curie Research Training Grant (to M.L.G.).

Goubillon, M.-L., Forsdike, R. A., Robinson, J. E., Ciofi, P., Caraty, A., & Herbison, A. E. (2000) · Endocrinology · doi:10.1210/endo.141.11.7743 · Cited by 137 · see citing works

Gonadectomy reveals sex differences in circadian rhythms and suprachiasmatic nucleus androgen receptors in mice

Iwahana, E., Karatsoreos, I., Shibata, S., & Silver, R. (2008) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.11.014 · Cited by 127 · see citing works

Optogenetic Stimulation of Arcuate Nucleus Kiss1 Neurons Reveals a Steroid-Dependent Glutamatergic Input to POMC and AgRP Neurons in Male Mice

Nestor, C. C., Qiu, J., Padilla, S. L., Zhang, C., Bosch, M. A., Fan, W., Aicher, S. A., Palmiter, R. D., Rønnekleiv, O. K., & Kelly, M. J. (2016) · Molecular Endocrinology · doi:10.1210/me.2016-1026 · Cited by 118 · see citing works

Neural Connections of Hypothalamic Neuroendocrine Nuclei in the Rat

Saeb‐Parsy, K., Lombardelli, Khan, McDowall, Au‐Yong, & Dyball (2000) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2000.00503.x · Cited by 116 · see citing works

Role of the Dorsal Medial Habenula in the Regulation of Voluntary Activity, Motor Function, Hedonic State, and Primary Reinforcement

Hsu, Y. A., Wang, S. D., Wang, S., Morton, G., Zariwala, H. A., de la Iglesia, H. O., & Turner, E. E. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1861-14.2014 · Cited by 115 · see citing works

Projections from the subparaventricular zone define four channels of output from the circadian timing system

Vujović, N., Gooley, J. J., Jhou, T. C., & Saper, C. B. (2015) · The Journal of Comparative Neurology · doi:10.1002/cne.23812 · Cited by 113 · see citing works

Leptin Signaling in AgRP Neurons Modulates Puberty Onset and Adult Fertility in Mice

Egan, O. K., Inglis, M. A., & Anderson, G. M. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3138-16.2017 · Cited by 113 · see citing works

DEPRIVATION AND SATIATION: THE INTERRELATIONS BETWEEN FOOD AND WHEEL RUNNING

Pierce, W. D., Epling, W. F., & Boer, D. P. (1986) · Journal of the Experimental Analysis of Behavior · doi:10.1901/jeab.1986.46-199 · Cited by 112 · see citing works

Estradiol suppresses rapid eye movement sleep and activation of sleep‐active neurons in the ventrolateral preoptic area

Hadjimarkou, M. M., Benham, R. S., Schwarz, J. M., Holder, M. K., & Mong, J. A. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06142.x · Cited by 110 · see citing works

Control of the Preovulatory Release of Luteinizing Hormone By Steroids in the Mouse*

Bronson, F. H., & Saal, F. S. V. (1979) · Endocrinology · doi:10.1210/endo-104-5-1247 · Cited by 110 · see citing works

Circadian desynchronization of core body temperature and sleep stages in the rat

Cambras, T., Weller, J. R., Anglès‐Pujolràs, M., Lee, M. L., Christopher, A. S., Dı́ez-Noguera, A., Krueger, J. M., & de la Iglesia, H. O. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0702424104 · Cited by 107 · see citing works

Sex differences in sensitivity of food intake body weight and running-wheel activity to ovarian steroids in rats.

Rt, G., & Gn, W. (1976) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0077246 · Cited by 103 · see citing works

Dominant Neuropeptide Cotransmission in Kisspeptin-GABA Regulation of GnRH Neuron Firing Driving Ovulation

Piet, R., Kalil, B., McLennan, T., Porteous, R. W., Czieselsky, K., & Herbison, A. E. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0658-18.2018 · Cited by 100 · see citing works

Environmental light and suprachiasmatic nucleus interact in the regulation of body temperature

Scheer, F. A. J. L., Pirovano, C., Someren, E. J. W. V., & Buijs, R. M. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2004.12.012 · Cited by 98 · see citing works

Estrogen Permits Vasopressin Signaling in Preoptic Kisspeptin Neurons in the Female Mouse

Piet, R., Fraissenon, A., Boehm, U., & Herbison, A. E. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.4587-14.2015 · Cited by 94 · see citing works

Kisspeptin: Beyond the Brain

Bhattacharya, M. M., & Babwah, A. V. (2015) · Endocrinology · doi:10.1210/en.2014-1915 · Cited by 86 · see citing works

Suprachiasmatic Nucleus Interaction with the Arcuate Nucleus; Essential for Organizing Physiological Rhythms

Buijs, F. N., Guzmán‐Ruiz, M. A., Mercado, L. L., Basualdo, M. C., Escobar, C., Kalsbeek, A., & Buijs, R. M. (2017) · eNeuro · doi:10.1523/eneuro.0028-17.2017 · Cited by 85 · see citing works

Manipulating Gene Expression in Projection‐Specific Neuronal Populations Using Combinatorial Viral Approaches

Gore, B. B., Soden, M. E., & Zweifel, L. S. (2013) · Current Protocols in Neuroscience · doi:10.1002/0471142301.ns0435s65 · Cited by 74 · see citing works

Ablation of KNDy Neurons Results in Hypogonadotropic Hypogonadism and Amplifies the Steroid-Induced LH Surge in Female Rats

Mittelman‐Smith, M. A., Krajewski, S. J., McMullen, N. T., & Rance, N. E. (2016) · Endocrinology · doi:10.1210/en.2015-1740 · Cited by 73 · see citing works

Suprachiasmatic Efferents Avoid Phenestrated Capillaries but Innervate Neuroendocrine Cells, Including Those Producing Dopamine*

Horvath, T. L. (1997) · Endocrinology · doi:10.1210/endo.138.3.4976 · Cited by 68 · see citing works

17β-Estradiol Increases Persistent Na+ Current and Excitability of AVPV/PeN Kiss1 Neurons in Female Mice

Zhang, C., Bosch, M. A., Qiu, J., Rønnekleiv, O. K., & Kelly, M. J. (2015) · Molecular Endocrinology · doi:10.1210/me.2014-1392 · Cited by 68 · see citing works

Presence of nuclear androgen receptor-like immunoreactivity in neurokinin B-containing neurons of the hypothalamic arcuate nucleus of the adult male rat

Ciofi, P., Krause, J. E., Prins, G. S., & Mazzuca, M. (1994) · Neuroscience Letters · doi:10.1016/0304-3940(94)90795-1 · Cited by 67 · see citing works

Effects of chronic forced circadian desynchronization on body weight and metabolism in male mice

Casiraghi, L. P., Alzamendi, A., Giovambattista, A., Chiesa, J. J., & Golombek, D. A. (2016) · Physiological Reports · doi:10.14814/phy2.12743 · Cited by 67 · see citing works

Oestrogen‐Independent Circadian Clock Gene Expression in the Anteroventral Periventricular Nucleus in Female Rats: Possible Role as an Integrator for Circadian and Ovarian Signals Timing the Luteinising Hormone Surge

Smarr, B. L., Gile, J. J., & de la Iglesia, H. O. (2013) · Journal of Neuroendocrinology · doi:10.1111/jne.12104 · Cited by 63 · see citing works

Role of the Suprachiasmatic and Arcuate Nuclei in Diurnal Temperature Regulation in the Rat

Guzmán‐Ruiz, M. A., Ramírez-Corona, A., Guerrero‐Vargas, N. N., Sabath, E., Ramírez‐Plascencia, O. D., Fuentes-Romero, R., Mercado, L. L., Sigales, M. B., Escobar, C., & Buijs, R. M. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.1449-15.2015 · Cited by 61 · see citing works

Contribution of locomotor activity to the generation of the daily rhythm of body temperature in golden hamsters

Refinetti, R. (1994) · Physiology & Behavior · doi:10.1016/0031-9384(94)90251-8 · Cited by 57 · see citing works

Circadian integration of sleep-wake and feeding requires NPY receptor-expressing neurons in the mediobasal hypothalamus

Wiater, M. F., Mukherjee, S., Li, A.-J., Dinh, T. T. N., Rooney, E., Simasko, S. M., & Ritter, S. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00168.2011 · Cited by 55 · see citing works

Detection of Successful and Unsuccessful Pregnancies in Mice within Hours of Pairing through Frequency Analysis of High Temporal Resolution Core Body Temperature Data

Smarr, B. L., Zucker, I., & Kriegsfeld, L. J. (2016) · PLOS ONE · doi:10.1371/journal.pone.0160127 · Cited by 54 · see citing works

Leptin-sensitive neurons in the arcuate nuclei contribute to endogenous feeding rhythms

Li, A., Wiater, M. F., Oostrom, M. T., Smith, B. R., Wang, Q., Dinh, T. T., Roberts, B. L., Jansen, H. T., & Ritter, S. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00086.2012 · Cited by 48 · see citing works

Regulation and Possible Functions of Kisspeptin in the Medial Amygdala

Stephens, S. B. Z., & Kauffman, A. S. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00191 · Cited by 35 · see citing works

Acetylcholine Encodes Long-Lasting Presynaptic Plasticity at Glutamatergic Synapses in the Dorsal Striatum after Repeated Amphetamine Exposure

Wang, W., Darvas, M., Storey, G. P., Bamford, I. J., Gibbs, J. T., Palmiter, R. D., & Bamford, N. S. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0014-13.2013 · Cited by 30 · see citing works

Fragmentation of Rapid Eye Movement and Nonrapid Eye Movement Sleep without Total Sleep Loss Impairs Hippocampus-Dependent Fear Memory Consolidation

Lee, M. L., Katsuyama, Â. M., Duge, L. S., Sriram, C., Krushelnytskyy, M. D., Kim, J. J., & de la Iglesia, H. O. (2016) · SLEEP · doi:10.5665/sleep.6236 · Cited by 24 · see citing works

Daily Luteinizing Hormone Release in Ovariectomized Hamsters: Effect of Barbiturate Blockade1

Stetson, M. H., Watson‐Whitmyre, M., Dipinto, M. N., & Smith, S. G. (1981) · Biology of Reproduction · doi:10.1095/biolreprod24.1.139 · Cited by 21 · see citing works

The Dorsal Medial Habenula Minimally Impacts Circadian Regulation of Locomotor Activity and Sleep

Hsu, Y. A., Gile, J. J., Perez, J. G., Morton, G., Ben‐Hamo, M., Turner, E. E., & de la Iglesia, H. O. (2017) · Journal of Biological Rhythms · doi:10.1177/0748730417730169 · Cited by 18 · see citing works

In Situ Hybridization of Suprachiasmatic Nucleus Slices

de la Iglesia, H. O. (2007) · Methods in molecular biology · doi:10.1007/978-1-59745-257-1_41 · Cited by 14 · see citing works

Decreased dendritic spine density as a consequence of tetanus toxin light chain expression in single neurons in vivo

Heimer‐McGinn, V., Murphy, A. C. H., Kim, J. C., Dymecki, S. M., & Young, P. W. (2013) · Neuroscience Letters · doi:10.1016/j.neulet.2013.09.007 · Cited by 11 · see citing works

Untitled work

(1997) · doi:10.1002/(sici)1096-9861(19971201)388:4

Temperature regulation in women: Effects of the menstrual cycle

Baker, F. C., Siboza, F., & Fuller, A. (2020) · Temperature · doi:10.1080/23328940.2020.1735927 · Cited by 262 · see citing works

Metabolic regulation of kisspeptin — the link between energy balance and reproduction

Navarro, V. M. (2020) · Nature Reviews Endocrinology · doi:10.1038/s41574-020-0363-7 · Cited by 240 · see citing works

Circadian rhythms and obesity: Timekeeping governs lipid metabolism

Li, Y., Ma, J., Kang, Y., Su, W., Tan, B., Wu, X., Huang, X., Li, T., Yin, Y., Tosini, G., et al. (2020) · Journal of Pineal Research · doi:10.1111/jpi.12682 · Cited by 159 · see citing works

Circadian Rhythms of the Hypothalamus: From Function to Physiology

Drunen, R. V., & Eckel‐Mahan, K. L. (2021) · Clocks & Sleep · doi:10.3390/clockssleep3010012 · Cited by 138 · see citing works

Role of core circadian clock genes in hormone release and target tissue sensitivity in the reproductive axis

Sen, A., & Hoffmann, H. M. (2019) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2019.110655 · Cited by 123 · see citing works

Regulation and function of extra‐SCN circadian oscillators in the brain

Begemann, K., Neumann, A., & Oster, H. (2020) · Acta Physiologica · doi:10.1111/apha.13446 · Cited by 102 · see citing works

Sleep disturbance associated with the menopause

Maki, P. M., Panay, N., & Simon, J. A. (2024) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0000000000002386 · Cited by 97 · see citing works

Neurogenetic basis for circadian regulation of metabolism by the hypothalamusPreprint

Cedernaes, J., Waldeck, N. J., & Bass, J. T. (2019) · Genes & Development · doi:10.1101/gad.328633.119 · Cited by 84 · see citing works

Snowballs in Africa: sectioning a long-lived Neoproterozoic carbonate platform and its bathyal foreslope (NW Namibia)

Hoffman, P. F., Halverson, G. P., Schrag, D. P., Higgins, J. A., Domack, E. W., Macdonald, F. A., Pruss, S. B., Blättler, C. L., Crockford, P. W., Hodgin, E. B., et al. (2021) · Earth-Science Reviews · doi:10.1016/j.earscirev.2021.103616 · Cited by 78 · see citing works

Sleep timing and the circadian clock in mammals: Past, present and the road ahead

Sanchez, R. E. A., Kalume, F. K., & de la Iglesia, H. O. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.05.034 · Cited by 71 · see citing works

Inputs and Outputs of the Mammalian Circadian Clock

Starnes, A. N., & Jones, J. R. (2023) · Biology · doi:10.3390/biology12040508 · Cited by 69 · see citing works

Differential Roles of Hypothalamic AVPV and Arcuate Kisspeptin Neurons in Estradiol Feedback Regulation of Female Reproduction

Wang, L., & Moenter, S. M. (2020) · Neuroendocrinology · doi:10.1159/000503006 · Cited by 63 · see citing works

The Emerging Therapeutic Potential of Kisspeptin and Neurokinin B

Patel, B., Koysombat, K., Mills, E., Tsoutsouki, J., Comninos, A. N., Abbara, A., & Dhillo, W. S. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnad023 · Cited by 61 · see citing works

Circadian Clock, Time-Restricted Feeding and Reproduction

Pan, X., Taylor, M. J., Cohen, E., Hanna, N. N., & Mota, S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21030831 · Cited by 53 · see citing works

Metabolic actions of kisspeptin signaling: Effects on body weight, energy expenditure, and feeding

Hudson, A. D., & Kauffman, A. S. (2021) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2021.107974 · Cited by 49 · see citing works

A maternal brain hormone that builds bone

Babey, M. E., Krause, W. C., Chen, K., Herber, C. B., Török, Z., Nikkanen, J., Rodríguez, R., Zhang, X., Navarro, F., Wang, Y., et al. (2024) · Nature · doi:10.1038/s41586-024-07634-3 · Cited by 54 · see citing works

Hypothalamic Kisspeptin Neurons and the Control of Homeostasis

Rønnekleiv, O. K., Qiu, J., & Kelly, M. J. (2021) · Endocrinology · doi:10.1210/endocr/bqab253 · Cited by 48 · see citing works

Gonadal hormone-dependent vs. -independent effects of kisspeptin signaling in the control of body weight and metabolic homeostasis

Velasco, I., León, S., Barroso, A., Ruíz-Pino, F., Heras, V., Torres, E., León, M., Ruohonen, S. T., García-Galiano, D., Romero‐Ruíz, A., et al. (2019) · Metabolism · doi:10.1016/j.metabol.2019.06.007 · Cited by 47 · see citing works

A reduction in voluntary physical activity in early pregnancy in mice is mediated by prolactin

Ladyman, S. R., Carter, K. M., Gillett, M. L., Aung, Z. K., & Grattan, D. R. (2021) · eLife · doi:10.7554/elife.62260 · Cited by 42 · see citing works

Suprachiasmatic Nucleus–Arcuate Nucleus Axis: Interaction Between Time and Metabolism Essential for Health

Méndez‐Hernández, R., Escobar, C., & Buijs, R. M. (2020) · Obesity · doi:10.1002/oby.22774 · Cited by 40 · see citing works

Arcuate nucleus, median eminence, and hypophysial pars tuberalis

Korf, H., & Møller, M. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-820107-7.00015-x · Cited by 38 · see citing works

Arcuate and Preoptic Kisspeptin Neurons Exhibit Differential Projections to Hypothalamic Nuclei and Exert Opposite Postsynaptic Effects on Hypothalamic Paraventricular and Dorsomedial Nuclei in the Female Mouse

Stincic, T. L., Qiu, J., Connors, A. M., Kelly, M. J., & Rønnekleiv, O. K. (2021) · eNeuro · doi:10.1523/eneuro.0093-21.2021 · Cited by 40 · see citing works

The circadian system: From clocks to physiology

Buijs, R. M., Soto‐Tinoco, E., Hurtado‐Alvarado, G., & Escobar, C. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-819975-6.00013-3 · Cited by 36 · see citing works

Arcuate Kisspeptin Neurons Coordinate Reproductive Activities with Metabolism

Rønnekleiv, O. K., Qiu, J., & Kelly, M. J. (2019) · Seminars in Reproductive Medicine · doi:10.1055/s-0039-3400251 · Cited by 38 · see citing works

Dissecting the Molecular Mechanisms Surrounding Post-COVID-19 Syndrome and Neurological Features

Mohamed, M. S., Johansson, A., Jonsson, J., & Schiöth, H. B. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084275 · Cited by 37 · see citing works

Kisspeptin-8 Induces Anxiety-Like Behavior and Hypolocomotion by Activating the HPA Axis and Increasing GABA Release in the Nucleus Accumbens in Rats

Ibos, K. E., Bodnár, É., Bagosi, Z., Bozsó, Z., Tóth, G., Szabó, G., & Csabafi, K. (2021) · Biomedicines · doi:10.3390/biomedicines9020112 · Cited by 34 · see citing works

Hypothalamic kisspeptin neurons as potential mediators of estradiol negative and positive feedback

Starrett, J. R., & Moenter, S. M. (2023) · Peptides · doi:10.1016/j.peptides.2023.170963 · Cited by 29 · see citing works

Circadian rhythms in the mouse reproductive axis during the estrous cycle and pregnancy

Yaw, A. M., Duong, T. V.-Q., Nguyen, D., & Hoffmann, H. M. (2020) · Journal of Neuroscience Research · doi:10.1002/jnr.24606 · Cited by 30 · see citing works

Optogenetic Activation of Arcuate Kisspeptin Neurons Generates a Luteinizing Hormone Surge-Like Secretion in an Estradiol-Dependent Manner

Lin, X.-H., Lass, G., Kong, L.-S., Wang, H., Li, X., Huang, H.-F., & O’Byrne, K. T. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.775233 · Cited by 30 · see citing works

Novel insights into the metabolic action of Kiss1 neurons

Talbi, R., & Navarro, V. M. (2020) · Endocrine Connections · doi:10.1530/ec-20-0068 · Cited by 28 · see citing works

Dissecting the KNDy hypothesis: KNDy neuron-derived kisspeptins are dispensable for puberty but essential for preserved female fertility and gonadotropin pulsatility

Velasco, I., Franssen, D., Daza‐Dueñas, S., Skrapits, K., Takács, S., Torres, E., Rodríguez-Vázquez, E., Ruiz-Cruz, M., León, S., Kukoricza, K., et al. (2023) · Metabolism · doi:10.1016/j.metabol.2023.155556 · Cited by 30 · see citing works

Arcuate Nucleus of the Hypothalamus: Anatomy, Physiology, and Diseases

Song, J., & Choi, S. (2023) · Experimental Neurobiology · doi:10.5607/en23040 · Cited by 32 · see citing works

The Effects of Kisspeptin on Brain Response to Food Images and Psychometric Parameters of Appetite in Healthy Men

Yang, L. Y., Demetriou, L., Wall, M. B., Mills, E., Wing, V. C., Thurston, L., Schaufelberger, C. N., Owen, B. M., Abbara, A., Rabiner, E. A., et al. (2020) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgaa746 · Cited by 26 · see citing works

Circadian influences on feeding behavior

la Fleur, S. E., Blancas‐Velazquez, A. S., Stenvers, D. J., & Kalsbeek, A. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.110007 · Cited by 27 · see citing works

Dopamine systems and biological rhythms: Let’s get a move on

Tang, Q., Assali, D. R., Güler, A. D., & Steele, A. D. (2022) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2022.957193 · Cited by 25 · see citing works

Arthropods: Why It Is So Crucial to Know Their Biodiversity?

Santos, J. C., de Almeida, W. R., & Fernandes, G. W. (2020) · Springer eBooks · doi:10.1007/978-3-030-53226-0_1 · Cited by 23 · see citing works

Deficiency of arcuate nucleus kisspeptin results in postpubertal central hypogonadism

Nandankar, N., Negrón, A. L., Wolfe, A., Levine, J. E., & Radovick, S. (2021) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00088.2021 · Cited by 24 · see citing works

Circadian Clock Deregulation and Metabolic Reprogramming: A System Biology Approach to Tissue-Specific Redox Signaling and Disease Development

Konakchieva, R., Mladenov, M. I., Konaktchieva, M. N., Sazdova, I., Gagov, H., & Nikolaev, G. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26136267 · Cited by 28 · see citing works

Role of the tumor microenvironment in regulating the anti-metastatic effect of KISS1

Harihar, S., Ray, S., Narayanan, S., Santhoshkumar, A., Ly, T., & Welch, D. R. (2020) · Clinical & Experimental Metastasis · doi:10.1007/s10585-020-10030-6 · Cited by 22 · see citing works

Nontraditional Risk Factors for Obesity in Modern Society

Han, S.-J., & Lee, S. (2021) · Journal of Obesity & Metabolic Syndrome · doi:10.7570/jomes21004 · Cited by 22 · see citing works

Emerging roles for kisspeptin in metabolism

Izzi‐Engbeaya, C. N., & Dhillo, W. S. (2021) · The Journal of Physiology · doi:10.1113/jp281712 · Cited by 22 · see citing works

Kisspeptin neuron electrophysiology: Intrinsic properties, hormonal modulation, and regulation of homeostatic circuits

Jamieson, B. B., & Piet, R. (2022) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2022.101006 · Cited by 23 · see citing works

In vivo recording of suprachiasmatic nucleus dynamics reveals a dominant role of arginine vasopressin neurons in circadian pacesetting

Tsuno, Y., Peng, Y., Horike, S., Wang, M., Matsui, A., Yamagata, K., Sugiyama, M., Nakamura, T. J., Daikoku, T., Maejima, T., et al. (2023) · PLoS Biology · doi:10.1371/journal.pbio.3002281 · Cited by 21 · see citing works

Role of central kisspeptin and RFRP‐3 in energy metabolism in the male Wistar rat

Cázarez‐Márquez, F., Eliveld, J., Ritsema, W. I. G. R., Foppen, E., Bossenbroek, Y., Pelizzari, S., Simonneaux, V., & Kalsbeek, A. (2021) · Journal of Neuroendocrinology · doi:10.1111/jne.12973 · Cited by 21 · see citing works

KISS1 metastasis suppressor in tumor dormancy: a potential therapeutic target for metastatic cancers?

Harihar, S., & Welch, D. R. (2023) · Cancer and Metastasis Reviews · doi:10.1007/s10555-023-10090-6 · Cited by 18 · see citing works

Running the Female Power Grid Across Lifespan Through Brain Estrogen Signaling

Ingraham, H. A., Herber, C. B., & Krause, W. C. (2021) · Annual Review of Physiology · doi:10.1146/annurev-physiol-061121-035914 · Cited by 17 · see citing works

Estrogenic regulation of reproduction and energy homeostasis by a triumvirate of hypothalamic arcuate neurons

Stincic, T. L., & Kelly, M. J. (2022) · Journal of Neuroendocrinology · doi:10.1111/jne.13145 · Cited by 17 · see citing works

Folate dose and form during pregnancy may program maternal and fetal health and disease risk

Pannia, E., Hammoud, R., Simonian, R., Kubant, R., & Anderson, G. H. (2022) · Nutrition Reviews · doi:10.1093/nutrit/nuac025 · Cited by 17 · see citing works

Circadian Regulation of the Brain and Behavior: A Neuroendocrine Perspective

Karatsoreos, I. N. (2019) · Current topics in behavioral neurosciences · doi:10.1007/7854_2019_115 · Cited by 16 · see citing works

An intricate relationship between circadian rhythm dysfunction and psychiatric diseases

Samanta, S., & Bagchi, D. (2024) · Exploration of neuroscience · doi:10.37349/en.2024.00053 · Cited by 16 · see citing works

Vasopressinergic Activity of the Suprachiasmatic Nucleus and mRNA Expression of Clock Genes in the Hypothalamus-Pituitary-Gonadal Axis in Female Aging

de Nicola, A. C., Ferreira, L. B., Mata, M. M., Vilhena‐Franco, T., Leite, C. M., Martins, A. B., Antunes‐Rodrigues, J., Poletini, M. O., & Dornelles, R. C. M. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.652733 · Cited by 15 · see citing works

Emerging roles of kisspeptin/galanin in age-related metabolic disease

Fang, P., She, Y., Zhao, J., Yan, J., Yu, X., Yu, J. Z., Wei, Q., Zhang, Z., & Shang, W. (2021) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2021.111571 · Cited by 14 · see citing works

Kisspeptin Neuron-Specific and Self-Sustained Calcium Oscillation in the Hypothalamic Arcuate Nucleus of Neonatal Mice: Regulatory Factors of its Synchronization

Kim, D., Jang, S., Kim, J., Park, I., Ku, K., Choi, M., Lee, S., Heo, W. D., Son, G. H., Choe, H. K., et al. (2020) · Neuroendocrinology · doi:10.1159/000505922 · Cited by 12 · see citing works

Competitive Inhibition of Cortisol by Prostaglandins at the Ligand Binding Domain of Glucocorticoid ReceptorsPreprint

Schaper, C. D. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/851501 · Cited by 12 · see citing works

Timing the Juvenile-Adult Neurohormonal Transition: Functions and Evolution

Barredo, C. G., Gil-Martí, B., Deveci, D., Romero, N. M., & Martín, F. A. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.602285 · Cited by 13 · see citing works

Novel actions of kisspeptin signaling outside of GnRH-mediated fertility: a potential role in energy balance

Patel, R. N., & Smith, J. T. (2020) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2020.106467 · Cited by 12 · see citing works

Thermoneutral conditions correct the obese phenotype in female, but not male, Kiss1r knockout mice

Halvorson, C. L., Bond, J. P. D., Maloney, S. K., & Smith, J. T. (2020) · Journal of Thermal Biology · doi:10.1016/j.jtherbio.2020.102592 · Cited by 11 · see citing works

Early Life Trauma, Emotion Dysregulation and Hormonal Sensitivity Across Female Reproductive Life Events

Tonon, A. C., Ramos-Lima, L. F., Kuhathasan, N., & Frey, B. N. (2024) · Current Psychiatry Reports · doi:10.1007/s11920-024-01527-y · Cited by 10 · see citing works

Differential temperature effects on photoperiodism in female voles: A possible explanation for declines in vole populations

van Rosmalen, L., Riedstra, B., Beemster, N., Dijkstra, C., & Hut, R. A. (2022) · Molecular Ecology · doi:10.1111/mec.16467 · Cited by 10 · see citing works

Sirtuin (SIRT)-1: At the crossroads of puberty and metabolism

Aylwin, C. F., & Lomniczi, A. (2020) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2020.06.001 · Cited by 10 · see citing works

FGF21 negatively affects long-term female fertility in mice

Moeckli, B., Pham, T.-V., Slits, F., Latrille, S., Peloso, A., Delaune, V., Oldani, G., Lacotte, S., & Toso, C. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e11490 · Cited by 9 · see citing works

Dopamine production in neurotensin receptor 1 neurons is required for diet‐induced obesity and increased day eating on a high‐fat diet

Farahmand, F., Sidikpramana, M., Gomez, A. R., Rivera, L. J., Trzeciak, J. R., Sharif, S., Tang, Q., Leinninger, G. M., Güler, A. D., & Steele, A. D. (2024) · Obesity · doi:10.1002/oby.24066 · Cited by 9 · see citing works

Multifaceted dynamics of circadian timing system influence aging and longevity

Jagota, A., Khan, Z. A., Sharma, S. A., & Priyanka (2025) · Biogerontology · doi:10.1007/s10522-025-10324-w · Cited by 9 · see citing works

Impacts of circadian disruptions on behavioral rhythms in mice

Ma, C., Shen, B., Chen, L., & Yang, G. (2024) · The FASEB Journal · doi:10.1096/fj.202401536r · Cited by 8 · see citing works

Kisspeptin impacts on circadian and ultradian rhythms of core body temperature: Evidence in kisspeptin receptor knockout and kisspeptin knockdown mice

Kavanagh, G. S., Tadi, J., Balkenhol, S. M., Kauffman, A. S., Maloney, S. K., & Smith, J. T. (2021) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2021.111530 · Cited by 8 · see citing works

Effects of obesity on the serum BMP15, GDF9, and kisspeptin concentrations in women of reproductive age

Arıkan, F. B., & Sağsöz, N. (2022) · Journal of Medical Biochemistry · doi:10.5937/jomb0-37329 · Cited by 8 · see citing works

Effect of Kisspeptin-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber Apostichopus japonicus

Guo, X., Zhang, L., & Xiao, K. (2023) · Animals · doi:10.3390/ani13040705 · Cited by 8 · see citing works

IGF-1 Acts through Kiss1-expressing Cells to Influence Metabolism and ReproductionPreprint

Wang, M., Pugh, S. M., Daboul, J., Miller, D., Xu, Y., & Hill, J. W. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.02.601722 · Cited by 7 · see citing works

Circadian disruption impairs Leydig cell maturation and reproductive development in male rats

Travicic, D. Z., Miljković, D., Andrić, S. A., & Kostic, T. S. (2025) · Reproductive Biology and Endocrinology · doi:10.1186/s12958-025-01440-w · Cited by 6 · see citing works

Neuronal feedback loop of the suprachiasmatic nucleus generates robust circadian rhythms

Wang, M., Tsuno, Y., Peng, Y., Islam, M. T., Matsui, A., Maejima, T., & Mieda, M. (2026) · Nature Communications · doi:10.1038/s41467-025-68218-x · Cited by 6 · see citing works

Hypothalamic circuits and aging: keeping the circadian clock updated

Vázquez-Lizárraga, R., Mendoza-Viveros, L., Cid‐Castro, C., Ruiz-Montoya, S., Carreño‐Vázquez, E., & Orozco-Solís, R. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.389624 · Cited by 6 · see citing works

A neural circadian signal essential for ovulation is generated in the suprachiasmatic nucleus during each stage of the oestrous cycle

Silva, C., Cortés, G. D., Javier, C. Y., Flores, A., & Domı́nguez, R. (2019) · Experimental Physiology · doi:10.1113/ep087942 · Cited by 6 · see citing works

Energy Homeostasis and Kisspeptin System, Roles of Exercise and Outcomes with a Focus on Male Reproductive Health

Ruggiero, M., Vicidomini, A., Tafuri, D., Mazzeo, F., & Meccariello, R. (2025) · Endocrines · doi:10.3390/endocrines6030043 · Cited by 6 · see citing works

Perinatal exposure to bisphenol A or S alters differently sexual behavior and kisspeptin system in mice

Bonaldo, B., Casile, A., Bettarelli, M., Marraudino, M., & Gotti, S. (2025) · Environmental Research · doi:10.1016/j.envres.2025.120888 · Cited by 5 · see citing works

Endemic Silurian ostracod faunas of the Southern Tien Shan, Central Asia

Михайлова, Е. Д., & Siveter, D. J. (2021) · Marine Micropaleontology · doi:10.1016/j.marmicro.2021.101969 · Cited by 5 · see citing works

TLR4-interactor with leucine-rich repeats (TRIL) is involved in diet-induced hypothalamic inflammation

Moura‐Assis, A., Nogueira, P. A. S., Júnior, J. C. D. L., Simabuco, F. M., Gaspar, J. M., Donato, J., & Velloso, L. A. (2021) · Scientific Reports · doi:10.1038/s41598-021-97291-7 · Cited by 5 · see citing works

The dual role of the angiosperm radiation on insect diversificationPreprint

Peris, D., & Condamine, F. L. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.07.527317 · Cited by 5 · see citing works

Exploring the Role of Polyunsaturated Fatty Acids in Children’s Sleep

Zhu, L., Zhu, B., & Yao, D. (2025) · Biomedicines · doi:10.3390/biomedicines13092045 · Cited by 4 · see citing works

Hypothalamic Cell Models

Dalvi, P. S., Loganathan, N., McIlwraith, E. K., Tran, A., & Belsham, D. D. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819801-8.00002-8 · Cited by 3 · see citing works

Genomic analysis of the carboxylesterase family in the salmon louse (Lepeophtheirus salmonis)

Tschesche, C., Bekaert, M., Humble, J. L., Bron, J. E., & Sturm, A. (2021) · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology · doi:10.1016/j.cbpc.2021.109095 · Cited by 3 · see citing works

Malpighian tubules in harvestmen

Lipovšek, S., Kozel, P., Leitinger, G., & Novak, T. (2021) · PROTOPLASMA · doi:10.1007/s00709-021-01634-0 · Cited by 3 · see citing works

Circadian regulation of maternal and feeding behaviors in lactating mice

Murakami, A., Masai, H., Kawamura, K., Matsumoto, K., Okamura, H., & Tominaga‐Yoshino, K. (2025) · Journal of Biological Rhythms · doi:10.1177/07487304251345655 · Cited by 2 · see citing works

Central Mechanisms Linking Age-Associated Physiological Changes to Health Span Through the Hypothalamus

Satoh, A. (2022) · Springer eBooks · doi:10.1007/978-981-16-7977-3_18 · Cited by 2 · see citing works

Synaptic plasticity and the role of astrocytes in central metabolic circuits

Ameroso, D., & Rios, M. (2023) · WIREs Mechanisms of Disease · doi:10.1002/wsbm.1632 · Cited by 3 · see citing works

Kisspeptins centrally modulate food intake and locomotor activity in mice independently of gonadal steroids in a sexually dimorphic manner

Velasco, I., Daza‐Dueñas, S., Torres, E., Ruíz-Pino, F., Vazquez, M. J., & Tena‐Sempere, M. (2024) · Journal of Neuroendocrinology · doi:10.1111/jne.13433 · Cited by 2 · see citing works

Circadian Control of Neuroendocrine Systems

Buijs, R. M., Soto‐Tinoco, E., & Kalsbeek, A. (2021) · Masterclass in neuroendocrinology · doi:10.1007/978-3-030-86630-3_11 · Cited by 2 · see citing works

The influence of estrogen response element ERα signaling in the control of feeding behaviors in male and female mice

Yasrebi, A., Regan, D., & Roepke, T. A. (2023) · Steroids · doi:10.1016/j.steroids.2023.109228 · Cited by 2 · see citing works

Identifying Integrative Molecular Pathways for Predictive Modeling of Infectious DiseasePreprint

Schaper, C. D. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/835546 · Cited by 2 · see citing works

Role of membrane estrogen receptor alpha on the negative feedback of estrogens on luteinizing hormone secretion

Faure, M., Corona, R., Vandries, L. M., Deconinck, C., Lenfant, F., Gérard, C., Foidart, J., & Cornil, C. A. (2025) · Journal of Neuroendocrinology · doi:10.1111/jne.70016 · Cited by 1 · see citing works

Moutan cortex ameliorates perimenopausal syndrome by regulating the KISS1R-ERK1/2-GnRH signaling pathway: Evidence from serum pharmacochemistry and network pharmacology

Huang, M., Wang, J., Ye, Y., Chen, W., Ai, X., Chen, X., Wang, Y., Wang, Y., & Xu, W. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.120732 · Cited by 1 · see citing works

KNDy kisspeptin is required for metabolic homeostasis in female mice in an ovarian hormone‐independent manner

Nandankar, N., Negrón, A. L., Ganesh, H., Youssef, N. N., Farooq, S. A., Al-Samerria, S., Levine, J. E., & Radovick, S. (2026) · Journal of Neuroendocrinology · doi:10.1111/jne.70208 · Cited by 1 · see citing works

The Effects of Insulin on Spike Activity of the Suprachiasmatic Nucleus Neurones and Functional State of Afferent Inputs from the Arcuate Nucleus in Rats

Inyushkin, A. N., Mistryugov, K. A., Ledyaeva, O. V., Romanova, I. D., Isakova, T. S., & Inyushkin, A. A. (2023) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093023010210 · Cited by 1 · see citing works

Sex-Specific Thermoregulatory Effects of Estrogen Signaling in Reprimo Lineage Cells

Park, J. W., Cortes, L. R., Sandoval, N. P., Vree, A. R., Baron, A. G., Vranich, K. A., Fideles, H. J., Martinez, R. M., Dilday, E. A., Hansen, M. R., et al. (2025) · Endocrinology · doi:10.1210/endocr/bqaf177 · Cited by 1 · see citing works

Aspects neurobiologiques du contrôle du comportement alimentaire

Magnan, C. (2021) · Les Obésités · doi:10.1016/b978-2-294-76753-1.00029-1

The Effects of Insulin on Spike Activity of the Suprachiasmatic Nucleus Neurones and Functional State of Afferent Inputs from the Arcuate Nucleus in Rats

Inyushkin, A. N., Mistryugov, K. A., Ledyaeva, O. V., Romanova, I. D., Isakova, T. S., & Inyushkin, A. A. (2023) · Российский физиологический журнал им  И  М  Сеченова · doi:10.31857/s086981392302005x

Exploring Rajaswala Paricharya: A Holistic Ayurvedic Perspective on Women's Well-being

Sirsat, A. (2024) · International Journal For Multidisciplinary Research · doi:10.36948/ijfmr.2024.v06i03.19453

Modulating effect of irisin on the functional state of inhibitory afferent inputs to the suprachiasmatic nucleus from the arcuate nucleus

Inyushkin, A. N., Павленко, С. И., Исакова, Т., Konashenkova, A., & Михайловна, И. Е. (2024) · BIO Web of Conferences · doi:10.1051/bioconf/202412101019

Reduced voluntary wheel running behaviour in Kiss1r knockout mice

Patel, R. N., Gomes, A., Maloney, S. K., & Smith, J. T. (2024) · Physiology & Behavior · doi:10.1016/j.physbeh.2024.114701

Sexually dimorphic distribution of Kiss1 neurons in the bed nucleus of the stria terminalis

Zdon, S. T., Silva, M. S. B., & Navarro, V. M. (2025) · Journal of Neuroendocrinology · doi:10.1111/jne.70049

Melanocortin-responsive Kiss1 neurons of the arcuate nucleus drive energy expenditure through glutamatergic signaling to the dorsomedial hypothalamusPreprint

Talbi, R., Stincic, T. L., Lynch, N. A., Torres, E., Ferrari, K., Hae, C. J., Medve, E., Walec, K. D., Zdon, S. T., Pereira, S. A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.06.25.661567

Novel insights into the metabolic action of Kiss1 neurons

Talbi, R., & Navarro, V. M. (2020) · Endocrine Connections · doi:10.1530/ec-20-0068 · Cited by 28 · see citing works

The effects of selective activation of kisspeptin neurons in hypothalamic arcuate nucleus on energy metabolism in mice

Li, Q., Liu, Q., Huang, G., Lin, W., Chen, G., & Wen, J. (2020) · Endocrine Abstracts · doi:10.1530/endoabs.70.aep1055

Novel actions of kisspeptin signaling outside of GnRH-mediated fertility: a potential role in energy balance

Patel, R. N., & Smith, J. T. (2020) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2020.106467 · Cited by 12 · see citing works

Hypothalamic Kisspeptin Neurons and the Control of Homeostasis

Rønnekleiv, O. K., Qiu, J., & Kelly, M. J. (2021) · Endocrinology · doi:10.1210/endocr/bqab253 · Cited by 48 · see citing works

Kisspeptin is present presynaptically in the rat arcuate nucleus and modulates neuronal activity at that site

Dyball, R. E. (2009) · Frontiers in Systems Neuroscience · doi:10.3389/conf.neuro.01.2009.04.107