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A Lumenal Domain-Dependent Pathway for Sorting to Intralumenal Vesicles of Multivesicular Endosomes Involved in Organelle Morphogenesis

Theos, Alexander C., Truschel, Steven T., Tenza, Daniele, Hurbain, Ilse, Harper, Dawn C., Berson, Joanne F., Thomas, Penelope C., Raposo, Graça, Marks, Michael S.·2006·Developmental Cell

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Crossref · 10.1016/j.devcel.2006.01.012

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  • The presence of ILVs within iridosomes supports an endosomal origin or an endosomal intermediate during iridosome formation and maturation.

    “Because ILVs are a hallmark of multivesicular bodies and are commonly observed during the maturation of multiple LRO types, including melanosomes and cytotoxic granules (86–88), their presence within iridosomes supports an endosomal origin or an endosomal intermediate during iridosome formation and maturation.”

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Metadata

Authors
Theos, A. C., Truschel, S. T., Tenza, D., Hurbain, I., Harper, D. C., Berson, J. F., Thomas, P. C., Raposo, G., & Marks, M. S.
Venue
Developmental Cell
Publisher
Elsevier BV
Published
2006-03
Volume
10
Issue
3
Pages
343-354
ISSN
1534-5807
Cited by
263
References
3
Language
en
Funders
  • American Cancer Society (PF-99-336-01-CIM)
  • National Cancer Institute
  • Centre National de la Recherche Scientifique
  • Institut Curie (T32-CA-009140)
  • National Institutes of Health (R01 AR 041855, R01 EY 015625)

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