Cited by 207Smoking Behavior and CessationNicotinic Acetylcholine Receptors StudyNeurotransmitter Receptor Influence on Behavior

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Functional brain imaging of tobacco use and dependence

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BRODY, A·2006·Journal of Psychiatric Research

DOI 10.1016/j.jpsychires.2005.04.012PMC PMC2876087

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Abstract

While most cigarette smokers endorse a desire to quit smoking, only about 14% to 49% will achieve abstinence after 6 months or more of treatment. A greater understanding of the effects of smoking on brain function may (in conjunction with other lines of research) result in improved pharmacological (and behavioral) interventions. Many research groups have examined the effects of acute and chronic nicotine/cigarette exposure on brain activity using functional imaging; the purpose of this paper is to synthesize findings from such studies and present a coherent model of brain function in smokers. Responses to acute administration of nicotine/smoking include: a reduction in global brain activity; activation of the prefrontal cortex, thalamus, and visual system; activation of the thalamus and visual cortex during visual cognitive tasks; and increased dopamine (DA) concentration in the ventral striatum/nucleus accumbens. Responses to chronic nicotine/cigarette exposure include decreased monoamine oxidase (MAO) A and B activity in the basal ganglia and a reduction in alpha4beta2 nicotinic acetylcholine receptor (nAChR) availability in the thalamus and putamen. Taken together, these findings indicate that smoking enhances neurotransmission through cortico-basal ganglia-thalamic circuits either by direct stimulation of nAChRs, indirect stimulation via DA release or MAO inhibition, or a combination of these factors. Activation of this circuitry may be responsible for the effects of smoking seen in tobacco dependent subjects, such as improvements in attentional performance, mood, anxiety, and irritability.

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Actual causes of death in the United States
McGinnis, J. M. (1993) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1993.03510180077038 · Cited by 5,480
Actual Causes of Death in the United States, 2000
Mokdad, A. H. (2004) · JAMA · doi:10.1001/jama.291.10.1238 · Cited by 5,211
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
Di Chiara, G., & Imperato, A. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.14.5274 · Cited by 4,733
Public Health Service
Bowman, P. W. (1963) · AIBS Bulletin · doi:10.2307/1292957 · Cited by 3,654
Autoradiographic localization of dopamine D1 and D2 receptors in rat nucleus accumbens: Resistance to differential rearing conditions
Bardo, M. T., & Hammer, R. P. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90226-e · Cited by 3,229
Storage and Executive Processes in the Frontal Lobes
Smith, E. E., & Jonides, J. (1999) · Science · doi:10.1126/science.283.5408.1657 · Cited by 2,834
Treating Tobacco Use and Dependence
(2008) · PEDIATRICS · doi:10.1542/peds.2008-1627 · Cited by 2,701
Subgenual prefrontal cortex abnormalities in mood disorders
Drevets, W. C., Price, J. L., Simpson, J. R., Todd, R. D., Reich, T., Vannier, M., & Raichle, M. E. (1997) · Nature · doi:10.1038/386824a0 · Cited by 2,693
Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex
Goldstein, R. Z., & Volkow, N. D. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.10.1642 · Cited by 2,667
Common regions of the human frontal lobe recruited by diverse cognitive demands
Duncan, J., & Owen, A. M. (2000) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01633-7 · Cited by 2,498
Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions.
Alexander, G. E., Crutcher, M. D., & DeLong, M. R. (1990) · PubMed · Cited by 2,422
Drugs of abuse: anatomy, pharmacology and function of reward pathways
Koob, G. F. (1992) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(92)90060-j · Cited by 2,070
Meta‐analysis of cue‐reactivity in addiction research
Carter, B. L., & Tiffany, S. T. (1999) · Addiction · doi:10.1046/j.1360-0443.1999.9433273.x · Cited by 1,638 · cited 1×
“Cigarette-related cues have been shown to reliably enhance craving during this period, when compared to neutral cues (Carter and Tiffany, 1999).”
Background
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation
Jorenby, D. E., Leischow, S. J., Nides, M. A., Rennard, S. I., Johnston, J. A., Hughes, A. R., Smith, S. S., Muramoto, M. L., Daughton, D. M., Doan, K., et al. (1999) · New England Journal of Medicine · doi:10.1056/nejm199903043400903 · Cited by 1,585
A Comparison of Sustained-Release Bupropion and Placebo for Smoking Cessation
Hurt, R. D., Sachs, D. P. L., Glover, E. D., Offord, K. P., Johnston, J. A., Dale, L. C., Khayrallah, M. A., Schroeder, D. R., Glover, P. N., Sullivan, C. R., et al. (1997) · New England Journal of Medicine · doi:10.1056/nejm199710233371703 · Cited by 1,262
Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs.
Pontieri, F. E., Tanda, G., Orzi, F., & Chiara, G. D. (1996) · Nature · doi:10.1038/382255a0 · Cited by 1,073
The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine
Corrigall, W. A., Franklin, K. B. J., Coen, K. M., & Clarke, P. B. S. (1992) · Psychopharmacology · doi:10.1007/bf02245149 · Cited by 829
Neuronal nicotinic receptors in the human brain
Paterson, D., & Nordberg, A. K. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(99)00045-3 · Cited by 792
Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area
Corrigall, W. A., Coen, K. M., & Adamson, K. L. (1994) · Brain Research · doi:10.1016/0006-8993(94)90401-4 · Cited by 740
Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas
Mansvelder, H. D., Keath, J. R., & McGehee, D. S. (2002) · Neuron · doi:10.1016/s0896-6273(02)00625-6 · Cited by 701
Neural activity in the human brain relating to uncertainty and arousal during anticipation.
Critchley, H. D., Mathias, C. J., & Dolan, R. J. (2001) · Neuron · doi:10.1016/s0896-6273(01)00225-2 · Cited by 681
Functional anatomy of thalamus and basal ganglia
Herrero, M.-T., Barcia, C., & Navarro, J. (2002) · Child s Nervous System · doi:10.1007/s00381-002-0604-1 · Cited by 660
Inhibition of monoamine oxidase B in the brains of smokers
Fowler, J. S., Volkow, N. D., Wang, G., Pappas, N. R., Logan, J., MacGregor, R. R., Alexoff, D. L., Shea, C. E., Schlyer, D. J., Wolf, A. P., et al. (1996) · Nature · doi:10.1038/379733a0 · Cited by 657
The Contribution of the Anterior Cingulate Cortex to Executive Processes in Cognition
Carter, C. S., Botvinick, M., & Cohen, J. D. (1999) · Reviews in the Neurosciences · doi:10.1515/revneuro.1999.10.1.49 · Cited by 641
Surveillance for certain health behaviors among states and selected local areas--Behavioral Risk Factor Surveillance System, United States, 2003.
Jiles, R. B., Hughes, E., Murphy, W., Flowers, N., McCracken, M., Roberts, H., Ochner, M., Balluz, L. S., Mokdad, A., Elam–Evans, L. D., et al. (2005) · PubMed · Cited by 596
Gustatory, olfactory, and visual convergence within the primate orbitofrontal cortex
Rolls, E., & Baylis, L. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-09-05437.1994 · Cited by 587
Evidence that Tobacco Smoking Increases the Density of (−)‐[3H]Nicotine Binding Sites in Human Brain
Benwell, M. E. M., Balfour, D. J. K., & Anderson, J. M. (1988) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1988.tb10600.x · Cited by 551
Application of toxicological risk assessment principles to the chemical constituents of cigarette smoke
Fowles, J. R., & Dybing, E. (2003) · Tobacco Control · doi:10.1136/tc.12.4.424 · Cited by 545
Nicotinic acetylcholine receptors: from structure to brain function
Hogg, R. C., Raggenbass, M., & Bertrand, D. (2003) · Springer eBooks · doi:10.1007/s10254-003-0005-1 · Cited by 536
An fMRI study of stroop word-color interference: evidence for cingulate subregions subserving multiple distributed attentional systems
Peterson, B. S., Skudlarski, P., Gatenby, J. C., Zhang, H., Anderson, A. W., & Gore, J. C. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00056-6 · Cited by 530
Systemic nicotine‐induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area
Nisell, M., Nomikos, G. G., & Svensson, T. H. (1994) · Synapse · doi:10.1002/syn.890160105 · Cited by 521
Nicotine-Induced Limbic Cortical Activation in the Human Brain: A Functional MRI Study
Stein, E. A., Pankiewicz, J., Harsch, H. H., Cho, J.-K., Fuller, S. A., Hoffmann, R. G., Hawkins, M., Rao, S. M., Bandettini, P. A., & Bloom, A. S. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.8.1009 · Cited by 483
Neuroimaging Studies of Attention: From Modulation of Sensory Processing to Top-Down Control
Pessoa, L., Kästner, S., & Ungerleider, L. G. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-10-03990.2003 · Cited by 463
Activation in Mesolimbic and Visuospatial Neural Circuits Elicited by Smoking Cues: Evidence From Functional Magnetic Resonance Imaging
Due, D. L., Huettel, S. A., HALL, W. G., & Rubin, D. C. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.6.954 · Cited by 437
Dopamine synaptic complex with pyramidal neurons in primate cerebral cortex.
Goldman-Rakic, P. S., Leranth, C., Williams, S. M., Mons, N. E., & Geffard, M. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.22.9015 · Cited by 429
Brain metabolic changes during cigarette craving
Brody, A. L., Mandelkern, M. A., London, E. D., Childress, A. R., Lee, G. S., Bota, R. G., Ho, M. L., Saxena, S., Baxter, L. R., Madsen, D., et al. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.12.1162 · Cited by 425
Self-citation
Brain monoamine oxidase A inhibition in cigarette smokers
Fowler, J. S., Volkow, N. D., Wang, G., Pappas, N. R., Logan, J., Shea, C. E., Alexoff, D. L., MacGregor, R. R., Schlyer, D. J., Zezulkova, I., et al. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.24.14065 · Cited by 424
Effects of nicotinic stimulation on cognitive performance
NEWHOUSE, P. A. (2003) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2003.11.001 · Cited by 411
Prefrontal responses to drug cues: a neurocognitive analysis
Wilson, S. J., Sayette, M. A., & Fiez, J. A. (2004) · Nature Neuroscience · doi:10.1038/nn1200 · Cited by 408
Effect of smoking history on [3H]nicotine binding in human postmortem brain
Breese, C. R., Marks, M. J., Logel, J., Adams, C. E., Sullivan, B., Collins, A. C., & Leonard, S. (1997) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36798-9 · Cited by 396
Smoking-Induced Ventral Striatum Dopamine Release
Brody, A. L., Olmstead, R. E., London, E. D., Farahi, J. B., Meyer, J. H., Grossman, P., Lee, G., Huang, J. C.-S., Hahn, E. L., & Mandelkern, M. A. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.7.1211 · Cited by 349
Self-citation
A Functional Anatomy of Anticipatory Anxiety
Chua, P. M.-L., Krams, M., Toni, I., Passingham, R. E., & Dolan, R. J. (1999) · NeuroImage · doi:10.1006/nimg.1999.0407 · Cited by 339
Cognitive Mechanisms of Nicotine on Visual Attention
Lawrence, N., Ross, T. J., & Stein, E. A. (2002) · Neuron · doi:10.1016/s0896-6273(02)01004-8 · Cited by 321
Neurobiology of the nicotine withdrawal syndrome
Kenny, P. J., & Markou, A. (2001) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(01)00651-7 · Cited by 310
Neuronal Systems Underlying Behaviors Related to Nicotine Addiction: Neural Circuits and Molecular Genetics
Picciotto, M. R., & Corrigall, W. A. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-09-03338.2002 · Cited by 265
[3H]cytisine binding to nicotinic cholinergic receptors in brain.
Pabreza, L. A., Dhawan, S., & Kellar, K. J. (1991) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10925-5 · Cited by 264
Nicotine Induces Glutamate Release from Thalamocortical Terminals in Prefrontal Cortex
Lambe, E. K., Picciotto, M. R., & Aghajanian, G. K. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300032 · Cited by 261
Autoradiographic distribution of nicotine receptors in rat brain
Clarke, P. B. S., Pert, C. B., & Pert, A. (1984) · Brain Research · doi:10.1016/0006-8993(84)90320-2 · Cited by 253
Regional brain activity during transient self-induced anxiety and anger in healthy adults
Kimbrell, T. A., George, M. S., Parekh, P. I., Ketter, T. A., Podell, D., Danielson, A., Repella, J. D., Benson, B. E., Willis, M. W., Herscovitch, P., et al. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00103-1 · Cited by 253
Monoamine oxidase and cigarette smoking
Fowler, J. S., Logan, J., Wang, G.-J., & Volkow, N. D. (2003) · NeuroToxicology · doi:10.1016/s0161-813x(02)00109-2 · Cited by 251
Sex differences in [123I]β‐CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers
Staley, J. K., Krishnan‐Sarin, S., Zoghbi, S. S., Tamagnan, G. D., Fujita, M., Seibyl, J. P., Maciejewski, P. K., O’Malley, S. S., & Innis, R. B. (2001) · Synapse · doi:10.1002/syn.1084 · Cited by 247
Cognitive effects of nicotine in humans: an fMRI study
Kumari, V., Gray, J. A., Ffytche, D. H., Mitterschiffthaler, M. T., Das, M., Zachariah, E., Vythelingum, G. N., Williams, S., Simmons, A., & Sharma, T. (2003) · NeuroImage · doi:10.1016/s1053-8119(03)00110-1 · Cited by 240
GABAB receptor agonists for the treatment of drug addiction: a review of recent findings
Cousins, M. S., Roberts, D. C. S., & de Wit, H. (2002) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(01)00163-6 · Cited by 240
Nicotine effects on brain function and functional connectivity in schizophrenia
Jacobsen, L. K., D’Souza, D. C., Mencl, W. E., Pugh, K. R., Skudlarski, P., & Krystal, J. H. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.12.023 · Cited by 236
Smoking History and Nicotine Effects on Cognitive Performance
Monique Ernst, D. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00257-3 · Cited by 232
An overview of the effects of tobacco ingredients on smoke chemistry and toxicity
Baker, R. R., Massey, E. D., & SMITH, G. M. (2004) · Food and Chemical Toxicology · doi:10.1016/j.fct.2004.01.001 · Cited by 230
The Primate Substantia Nigra and VTA: Integrative Circuitry and Function
Haber, S. N., & Fudge, J. L. (1997) · Critical Reviews in Neurobiology · doi:10.1615/critrevneurobiol.v11.i4.40 · Cited by 228
The role of the thalamus in motor control
Sommer, M. A. (2003) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2003.10.014 · Cited by 225
Modulation of dopamine efflux in the nucleus accumbens after cholinergic stimulation of the ventral tegmental area in intact, pedunculopontine tegmental nucleus-lesioned, and laterodorsal tegmental nucleus-lesioned rats
Blaha, C. D., Allen, L., Das, S., Inglis, W. L., LATIMER, M. L., Vincent, S., & Winn, P. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-02-00714.1996 · Cited by 223
Drugs of Abuse and the Brain
Leshner, A. I., & Koob, G. F. (1999) · Proceedings of the Association of American Physicians · doi:10.1046/j.1525-1381.1999.09218.x · Cited by 220
Nicotine Blood Levels and Subjective Craving for Cigarettes
Jarvik, M. E., Madsen, D. C., Olmstead, R. E., Iwamoto‐Schaap, P. N., Elins, J. L., & BENOWITZ, N. (2000) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(00)00261-6 · Cited by 217
Neural activity in the human brain relating to uncertainty and arousal during anticipation
Critchley, H., Mathiast, C. J., & Dolan, R. J. (2001) · NeuroImage · doi:10.1016/s1053-8119(01)91735-5 · Cited by 191
Nicotinic receptors in the rat prefrontal cortex: increase in glutamate release and facilitation of mediodorsal thalamo‐cortical transmission
Gioanni, Y., Rougeot, C., Clarke, P. B. S., Lepousé, C., Thierry, A. M., & Vidal, C. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00403.x · Cited by 191
Corticothalamic interactions in the transfer of visual information
Sillito, A. M., & Jones, H. E. (2002) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2002.1170 · Cited by 191
Dose‐related neuroprotective effects of chronic nicotine in 6‐hydroxydopamine treated rats, and loss of neuroprotection in α4 nicotinic receptor subunit knockout mice
Ryan, R. E., Ross, S. A., Drago, J., & Loiacono, R. E. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703989 · Cited by 188
Nicotine abstinence produces content-specific Stroop interference
Gross, T. M., Jarvik, M. E., & Rosenblatt, M. R. (1993) · Psychopharmacology · doi:10.1007/bf02251289 · Cited by 188
Nicotinic receptors in human brain: topography and pathology
Court, J. A., Martin-Ruiz, C., Graham, A., & Perry, E. (2000) · Journal of Chemical Neuroanatomy · doi:10.1016/s0891-0618(00)00110-1 · Cited by 180
Effect of nicotine on brain activation during performance of a working memory task
Monique Ernst, D., Matochik, J. A., Heishman, S. J., Horn, J. D. V., Jons, P. H., Henningfield, J. E., & London, E. D. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.061369098 · Cited by 178
The hedonic response to cigarette smoking is proportional to dopamine release in the human striatum as measured by positron emission tomography and [11C]raclopride
Barrett, S. P., Boileau, I., Okker, J., Pihl, R. O., & Dagher, A. (2004) · Synapse · doi:10.1002/syn.20066 · Cited by 177
5-Iodo-A-85380, an α4β2 Subtype-Selective Ligand for Nicotinic Acetylcholine Receptors
Mukhin, A. G., Gündisch, D., Horti, A. G., Koren, A. O., Tamagnan, G., Kimes, A. S., Chambers, J., Vaupel, D. B., King, S. L., Picciotto, M. R., et al. (2000) · Molecular Pharmacology · doi:10.1124/mol.57.3.642 · Cited by 173
Lack of tolerance to nicotine-induced dopamine release in the nucleus accumbens
Damsma, G., Day, J. C., & Fibiger, H. C. (1989) · European Journal of Pharmacology · doi:10.1016/0014-2999(89)90798-x · Cited by 170
High Levels of Dopamine Activity in the Basal Ganglia of Cigarette Smokers
Salokangas, R. K. R., Vilkman, H., Ilonen, T., Taiminen, T., Bergman, J., Haaparanta, M., Solin, O., Alanen, A., Syvã«¡hti, E., & Hietala, J. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.4.632 · Cited by 164 · cited 1×
“…of the DA system have reported decreased D1 receptor density (Dagher et al., 2001), increased 18F-DOPA uptake (a marker for increased DA turnover) (Salokangas et al., 2000a), and both decreased (Krause et al., 2002) and no alterations (Staley et al., 2001) in dopamine transporter binding in…”
Background
Fast Reaction to Different Sensory Modalities Activates Common Fields in the Motor Areas, but the Anterior Cingulate Cortex is Involved in the Speed of Reaction
Naito, E., Kinomura, S., Geyer, S., Kawashima, R., Roland, P. E., & Zilles, K. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.3.1701 · Cited by 163
Nicotine withdrawal in chippers and regular smokers: Subjective and cognitive effects.
Shiffman, S. S., Paty, J. A., Gnys, M., Kassel, J. D., & al, E. (1995) · Health Psychology · doi:10.1037/0278-6133.14.4.301 · Cited by 160
Attenuation of cue-induced cigarette craving and anterior cingulate cortex activation in bupropion-treated smokers: a preliminary study
Brody, A. L., Mandelkern, M. A., Lee, G., Smith, E. C., Sadeghi, M., Saxena, S., Jarvik, M. E., & London, E. D. (2004) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2003.12.006 · Cited by 158
Self-citation
[3H]epibatidine labels nicotinic receptors in rat brain: an autoradiographic study.
Perry, D. C., & Kellar, K. J. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)12091-0 · Cited by 158
Stimulation of [3H]Dopamine Release by Nicotine in Rat Nucleus Accumbens
Rowell, P. P., Carr, L. A., & Garner, A. C. (1987) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1987.tb01013.x · Cited by 154
Monoamine oxidases and tobacco smoking
Berlin, I., & Anthenelli, R. M. (2001) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145701002188 · Cited by 149
Slow recovery of human brain MAO B after L‐Deprenyl (Selegeline) withdrawal
Fowler, J. S., Volkow, N. D., Logan, J., Wang, G., Gregor, R. R. M., Schlyer, D. J., Wolf, A. P., Pappas, N. R., Alexoff, D. L., Shea, C. E., et al. (1994) · Synapse · doi:10.1002/syn.890180203 · Cited by 147
Integration and segregation of limbic cortico-striatal loops at the thalamic level: an experimental tracing study in rats
Groenewegen, H. J., Graaf, Y. G.-D., & Smeets, W. J. A. J. (1999) · Journal of Chemical Neuroanatomy · doi:10.1016/s0891-0618(99)00009-5 · Cited by 144
Are higher doses of nicotine replacement more effective for smoking cessation?
Hughes, J. R., Lesmes, G. R., Hatsukami, D. K., RICHMOND, R. L., Lichtenstein, E. H., Jorenby, D. E., Broughton, J. O., Fortmann, S. P., Leischow, S. J., McKenna, J., et al. (1999) · Nicotine & Tobacco Research · doi:10.1080/14622299050011281 · Cited by 143
Fire Injuries, Disasters, and Costs from Cigarettes and Cigarette Lights: A Global Overview
Leistikow, B. N., Martin, D. C., & Milano, C. E. (2000) · Preventive Medicine · doi:10.1006/pmed.2000.0680 · Cited by 143
Both Nicotinic and Muscarinic Receptors in Ventral Tegmental Area Contribute to Brain-Stimulation Reward
Yeomans, J. S., & Baptista, M. A. S. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(96)00467-4 · Cited by 139
Smoking, reward responsiveness, and response inhibition: tests of an incentive motivational model
Powell, J. E., Dawkins, L., & Davis, R. E. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01208-2 · Cited by 137
PET Studies of the Influences of Nicotine on Neural Systems in Cigarette Smokers
Rose, J. E., Behm, F. M., Westman, E. C., Mathew, R. J., London, E. D., Hawk, T. C., Turkington, T. G., & Coleman, R. E. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.2.323 · Cited by 136
Neural activation during sexual and competitive arousal in healthy men
Rauch, S. L., Shin, L. M., Dougherty, D. D., Alpert, N. M., Orr, S. P., Lasko, M. C., Macklin, M. L., Fischman, A. J., & Pitman, R. K. (1999) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(99)00020-7 · Cited by 132
Reduced dopamine d1 receptor binding in the ventral striatum of cigarette smokers
Dagher, A., Bleicher, C., Aston, J. A. D., Gunn, R. N., Clarke, P. B. S., & Cumming, P. (2001) · Synapse · doi:10.1002/syn.1098 · Cited by 132
Desire to smoke during spaced smoking intervals
Schuh, K. J., & Stitzer, M. L. (1995) · Psychopharmacology · doi:10.1007/bf02311176 · Cited by 131
Regional release of [3H]dopamine from rat brain in vitro: effects of opioids on release induced by potassium, nicotine, and L -glutamic acid
Marien, M. R., Brien, J. F., & Jhamandas, K. H. (1983) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y83-005 · Cited by 127
Chronic nicotine and mecamylamine treatment increase brain nicotinic receptor binding without changing alpha 4 or beta 2 mRNA levels
Pauly, J. R., Marks, M. J., Robinson, S. F., van de Kamp, J. L., & Collins, A. C. (1996) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)20143-4 · Cited by 126
Health effects of tobacco use and exposure.
Bartal, M. (2001) · PubMed · Cited by 125
2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: Synthesis, Affinity for Nicotinic Acetylcholine Receptors, and Molecular Modeling
Koren, A. O., Horti, A. G., Mukhin, A. G., Gündisch, D., Kimes, A. S., Dannals, R. F., & London, E. D. (1998) · Journal of Medicinal Chemistry · doi:10.1021/jm980170a · Cited by 125
Neuropharmacological Actions of Cigarette Smoke
Fowler, J. S., Volkow, N. D., Wang, G., Pappas, N. R., Logan, J., MacGregor, R. R., Alexoff, D. L., Wolf, A. P., Warner, D., Cilento, R., et al. (1998) · Journal of Addictive Diseases · doi:10.1300/j069v17n01_03 · Cited by 124
Autoradiographic localization of [3H]nicotine binding sites in the rat brain
London, E. D., Waller, S. B., & Wamsley, J. K. (1985) · Neuroscience Letters · doi:10.1016/0304-3940(85)90182-x · Cited by 123
The pedunculopontine tegmental nucleus and the role of cholinergic neurons in nicotine self-administration in the rat: a correlative neuroanatomical and behavioral study
Lança, A. J., Adamson, K. L., Coen, K. M., Chow, B. L., & Corrigall, W. (2000) · Neuroscience · doi:10.1016/s0306-4522(99)00607-7 · Cited by 120
Blood–brain barrier, brain metabolism and cerebral blood flow
Paulson, O. B. (2002) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(02)00098-6 · Cited by 117
Cigarette smoking decreases cerebral blood flow suggesting increased risk for stroke.
Rogers, R. L., Meyer, J. S., Shaw, T. G., Mortel, K. F., Hardenberg, J. P., & Zaid, R. R. (1983) · PubMed · Cited by 116
Effects of nicotine on local cerebral glucose utilization in the rat
Ed, L., Connolly, R., Szikszay, M., Wamsley, J. K., & Dam, M. (1988) · Journal of Neuroscience · doi:10.1523/jneurosci.08-10-03920.1988 · Cited by 115
2 [ 18 F]F‐A85380: PET imaging of brain nicotinic acetylcholine receptors and whole body distribution in humans
Kimes, A. S., Horti, A. G., London, E. D., Chefer, S. I., Contoreggi, C. S., Ernst, M., Friello, P. J., Koren, A. O., Kurian, V., Matochik, J. A., et al. (2003) · The FASEB Journal · doi:10.1096/fj.02-0492fje · Cited by 114
What can functional imaging reveal about the role of attention in visual awareness?
Rees, G. E., & Lavie, N. (2001) · Neuropsychologia · doi:10.1016/s0028-3932(01)00122-1 · Cited by 107
Smoking after nicotine deprivation enhances cognitive performance and decreases tobacco craving in drug abusers
Bell, S., Taylor, R., Singleton, E., Henningfield, J., & Heishman, S. (1999) · Nicotine & Tobacco Research · doi:10.1080/14622299050011141 · Cited by 107
Release of dopamine and 5-hydroxytryptamine from rat striatal slices following activation of nicotinic cholinergic receptors
Westfall, T. C., Grant, H., & Perry, H. (1983) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(83)90037-x · Cited by 102
Cerebral effects of nicotine during cognition in smokers and non-smokers
Ghatan, P. H., Ingvar, M., Eriksson, L., Stone‐Elander, S., Serrander, M., Ekberg, K., & Wahren, J. (1998) · Psychopharmacology · doi:10.1007/s002130050554 · Cited by 93
Collateral projections from the supramammillary nucleus to the medial septum and hippocampus
Vertes, R. P., & McKenna, J. T. (2000) · Synapse · doi:10.1002/1098-2396(20001201)38:3 · Cited by 92
Comparative effects of methamphetamine and nicotine on the striatal [11C]raclopride binding in unanesthetized monkeys
Tsukada, H., Miyasato, K., Kakiuchi, T., Nishiyama, S., Harada, N., & Domino, E. F. (2002) · Synapse · doi:10.1002/syn.10102 · Cited by 91
[125I]IPH, an Epibatidine Analog, Binds with High Affinity to Neuronal Nicotinic Cholinergic Receptors
Dávila‐García, M. I., Musachio, J. L., Perry, D. C., Xiao, Y., Horti, A. G., London, E. D., Dannals, R. F., & Kellar, K. J. (1997) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)36785-0 · Cited by 90
Regional cerebral blood flow effects of nicotine in overnight abstinent smokers
Zubieta, J., Lombardi, U., Minoshima, S., Guthrie, S. K., Ni, L., Ohl, L. E., Koeppe, R. A., & Domino, E. F. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01070-2 · Cited by 89
Nicotine patch and paroxetine for smoking cessation.
Killen, J. D., Fortmann, S. P., Schatzberg, A. F., Hayward, C., Sussman, L. K., Rothman, M. S., Strausberg, L., & Varady, A. N. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.68.5.883 · Cited by 89
Distribution of nicotinic receptors in cynomolgus monkey brain and ganglia: Localization of α3 subunit mRNA, α-bungarotoxin and nicotine binding sites
Cimino, M., Marini, P., Fornasari, D., Cattabeni, F., & Clementi, F. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90472-e · Cited by 88
Stimulant-like action of nicotine on striatal dopamine transporter in the brain of adults with attention deficit hyperactivity disorder
Krause, K.-H., Dresel, S. H., Krause, J., Kung, H. F., Tatsch, K., & Ackenheil, M. (2002) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145702002821 · Cited by 88
6-[18F]fluoro-A-85380: an in vivo tracer for the nicotinic acetylcholine receptor
Scheffel, U., Horti, A. G., Koren, A. O., Ravert, H. T., Banta, J. P., Finley, P. A., London, E. D., & Dannals, R. F. (2000) · Nuclear Medicine and Biology · doi:10.1016/s0969-8051(99)00082-7 · Cited by 87
An autoradiographic analysis of cholinergic receptors in mouse brain
Pauly, J. R., Stitzel, J. A., Marks, M. J., & Collins, A. C. (1989) · Brain Research Bulletin · doi:10.1016/0361-9230(89)90072-5 · Cited by 86
Low monoamine oxidase B in peripheral organs in smokers
Fowler, J. S., Logan, J., Wang, G., Volkow, N. D., Telang, F., Zhu, W., Franceschi, D., Pappas, N. R., Ferrieri, R. A., Shea, C. E., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1833106100 · Cited by 86
Enhancement of [3H]dopamine release and its [3H]metabolites in rat striatum by nicotinic drugs
Sakurai, Y., Takano, Y., Kohjimoto, Y., Honda, K., & Kamiya, H. (1982) · Brain Research · doi:10.1016/0006-8993(82)90499-1 · Cited by 86
Cigarette-Derived Nicotine is not a Medicine
Parrott, A. C. (2003) · The World Journal of Biological Psychiatry · doi:10.3109/15622970309167951 · Cited by 85
The Effects of Varying Cigarette Deprivation Duration on Cognitive and Performance Tasks
Hatsukami, D. K., Fletcher, L. A., Morgan, S. F., Keenan, R. M., & Amble, P. (1989) · Journal of Substance Abuse · doi:10.1016/s0899-3289(20)30005-5 · Cited by 85
Effects of smoking on regional cerebral blood flow in neurologically normal subjects.
Kubota, K., Yamaguchi, T., Abe, Y., Fujiwara, T., Hatazawa, J., & Matsuzawa, T. (1983) · Stroke · doi:10.1161/01.str.14.5.720 · Cited by 83
Graphical analysis of 2‐[18F]FA binding to nicotinic acetylcholine receptors in rhesus monkey brain
Chefer, S. I., London, E. D., Koren, A. O., Pavlova, O. A., Kurian, V., Kimes, A. S., Horti, A. G., & Mukhin, A. G. (2003) · Synapse · doi:10.1002/syn.10180 · Cited by 82
The Neurophysiology of Taste and Olfaction in Primates, and Umami Flavora
ROLLS, E. T., CRITCHLEY, H. D., BROWNING, A., & HERNADI, I. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb10602.x · Cited by 80
Surveillance for Certain Health Behaviors Among Selected Local Areas--United States, Behavioral Risk Factor Surveillance System, 2002
Balluz, L. S., Ahluwalia, I. B., Murphy, W., Mokdad, A. H., Giles, W. H., & Harris, V. B. (2004) · PsycEXTRA Dataset · doi:10.1037/e307162005-001 · Cited by 77
Effects of nicotine on regional cerebral glucose metabolism in awake resting tobacco smokers
Domino, E. F., Minoshima, S., Guthrie, S. K., Ohl, L. E., Ni, L., Koeppe, R. A., Cross, D. J., & Zubieta, J. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00357-2 · Cited by 76
Behavioural and biochemical adaptations to nicotine in rats: influence of MK801, an NMDA receptor antagonist
Shoaib, M., Schindler, C. W., Goldberg, S. R., & Pauly, J. R. (1997) · Psychopharmacology · doi:10.1007/s002130050433 · Cited by 72
Imaging central nicotinic acetylcholine receptors in baboons with [18F]fluoro-A-85380.
Valette, H., Bottlaender, M., Dollé, F., Guenther, I., Fuseau, C., Coulon, C., Ottaviani, M., & Crouzel, C. (1999) · PubMed · Cited by 69
Acute effects of smoking on blood pressure and cerebral blood flow.
Cruickshank, J. M., Neil-Dwyer, G., Dorrance, D. E., Hayes, Y., & Patel, S. (1989) · PubMed · Cited by 68
Maintenance of Brain Monoamine Oxidase B Inhibition in Smokers After Overnight Cigarette Abstinence
Fowler, J. S., Wang, G., Volkow, N. D., Franceschi, D., Logan, J., Pappas, N. R., Shea, C. E., MacGregor, R. R., & Garza, V. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.11.1864 · Cited by 68
2-[18F]fluoro-A-85380, an in vivo tracer for the nicotinic acetylcholine receptors
Horti, A. G., Scheffel, U., Koren, A. O., Ravert, H. T., Mathews, W. B., Musachio, J. L., Finley, P. A., London, E. D., & Dannals, R. F. (1998) · Nuclear Medicine and Biology · doi:10.1016/s0969-8051(98)00031-6 · Cited by 68
Up-regulation of nicotinic acetylcholine receptors following chronic exposure of rats to mainstream cigarette smoke or α4β2 receptors to nicotine
Yates, S. L., Bencheri, M., Fluhler, E. N., & Lippiello, P. M. (1995) · Biochemical Pharmacology · doi:10.1016/0006-2952(95)02100-0 · Cited by 65
Do heavy smokers benefit from higher dose nicotine patch therapy?
Killen, J. D., Fortmann, S. P., Davis, L., Strausberg, L., & Varady, A. N. (1999) · Experimental and Clinical Psychopharmacology · doi:10.1037//1064-1297.7.3.226 · Cited by 63
In vivo imaging of brain nicotinic acetylcholine receptors with 5-[123I]iodo-A-85380 using single photon emission computed tomography
Chefer, S. I., Horti, A. G., Lee, K. S., Koren, A. O., Jones, D. W., Gorey, J. G., Links, J. M., Mukhin, A. G., Weinberger, D. R., & London, E. D. (1998) · Life Sciences · doi:10.1016/s0024-3205(98)00514-1 · Cited by 63
Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [123I]5-I-A-85380 in healthy human subjects
Fujita, M., Seibyl, J. P., Vaupel, B. D., Tamagnan, G., Early, M., Zoghbi, S. S., Baldwin, R. M., Horti, A. G., Koren, A. O., Mukhin, A. G., et al. (2002) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-001-0695-z · Cited by 62
Nicotine-Induced Dopamine Release in Primates Measured with [11C]Raclopride PET
Marenco, S., Carson, R. E., Berman, K. F., Herscovitch, P., & Weinberger, D. R. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300287 · Cited by 62
Chapter 4 Thalamic relay functions
Sherman, S. M. (2001) · Progress in brain research · doi:10.1016/s0079-6123(01)34005-0 · Cited by 60
Impact of intravenous nicotine on BOLD signal response to photic stimulation
Jacobsen, L. K., Gore, J. C., Skudlarski, P., Lacadie, C., Jatlow, P. L., & Krystal, J. H. (2002) · Magnetic Resonance Imaging · doi:10.1016/s0730-725x(02)00494-0 · Cited by 60
Facilitatory modulation of mesolimbic dopamine neuronal activity by a μ-opioid agonist and nicotine as examined with in vivo microdialysis
Yoshida, M., Yokoo, H., Tanaka, T., Mizoguchi, K., Emoto, H., Ishii, H., & Tanaka, M. (1993) · Brain Research · doi:10.1016/0006-8993(93)90087-4 · Cited by 59
Placebo effects of tobacco smoking and other nicotine intake
Perkins, K. A., Sayette, M. A., Conklin, C. A., & Caggiula, A. R. (2003) · Nicotine & Tobacco Research · doi:10.1080/1462220031000158636 · Cited by 58
Effects of Long-term Cigarette Smoking on the Human Locus Coeruleus
Klimek, V., Zhu, M., Dilley, G. E., Konick, L. C., Overholser, J. C., Meltzer, H. Y., May, W. L., Stockmeier, C. A., & Ordway, G. A. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.9.821 · Cited by 58
Imaging nicotinic acetylcholine receptors with fluorine-18-FPH, an epibatidine analog.
Villemagne, V. L., Horti, A. G., Scheffel, U., Ravert, H. T., Finley, P. A., Clough, D. J., London, E. D., Wagner, H. N., & Dannals, R. F. (1997) · PubMed · Cited by 58
Enhancement of continuous performance task reaction time by smoking in non-deprived smokers
Pritchard, W. S., Robinson, J. H., & Guy, T. D. (1992) · Psychopharmacology · doi:10.1007/bf02247417 · Cited by 57
Chronic nicotine and smoking treatment increases dopamine transporter mRNA expression in the rat midbrain
Li, S., Kim, K. Y., Kim, J. H., Kim, J., Park, M. S., Bahk, J. Y., & Kim, M. O. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.03.053 · Cited by 57
Intravenous Nicotine Reduces Cerebral Glucose Metabolism: A Preliminary Study
Stapleton, J. M., Gilson, S. F., Wong, D. F., Villemagne, V. L., Dannals, R. F., GRAYSON, R. F., Henningfield, J. E., & London, E. D. (2002) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300106 · Cited by 52
Moving out of the laboratory: does nicotine improve everyday attention?
Rusted, J. M., Caulfield, D., King, L., & Goode, A. (2000) · Behavioral Pharmacology · doi:10.1097/00008877-200011000-00009 · Cited by 51
Neuronal Nicotinic Acetylcholine Receptors
Lukas, R. J. (1998) · Springer eBooks · doi:10.1007/978-3-662-40279-5_7 · Cited by 50
Smoking a single cigarette does not produce a measurable reduction in brain MAO B in non-smokers
Fowler, J. S., Wang, G., Volkow, N. D., Franceschi, D., Logan, J., Pappas, N. R., Shea, C. E., MacGregor, R. R., & Garza, V. (1999) · Nicotine & Tobacco Research · doi:10.1080/14622299050011451 · Cited by 49
Radiosynthesis and preliminary evaluation of 5-[123/125I]iodo-3-(2(S)-azetidinylmethoxy)pyridine: a radioligand for nicotinic acetylcholine receptors
Horti, A. G., Koren, A. O., Lee, K. S., Mukhin, A. G., Vaupel, D. B., Kimes, A. S., Stratton, M., & London, E. D. (1999) · Nuclear Medicine and Biology · doi:10.1016/s0969-8051(98)00086-9 · Cited by 48
In vivo specific binding of [3H]-1-nicotine in the mouse brain
Broussolle, E. P., Wong, D. F., Fanelli, R. J., & London, E. D. (1989) · Life Sciences · doi:10.1016/0024-3205(89)90340-8 · Cited by 47
Quantification of nicotinic acetylcholine receptors in human brain using [123I]5-I-A-85380 SPET
Fujita, M., Ichise, M., van Dyck, C., Zoghbi, S., Tamagnan, G., Mukhin, A., Bozkurt, A., Seneca, N., Tipre, D., Denucci, C. C., et al. (2003) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-003-1320-0 · Cited by 47
In vivo labeling of nicotinic acetylcholine receptors in brain with [3H]epibatidine
London, E. D., Scheffel, U., Kimes, A. S., & Kellar, K. J. (1995) · European Journal of Pharmacology · doi:10.1016/0014-2999(95)00178-n · Cited by 46
Dopamine D1 and D2 receptor mRNA up-regulation in the caudate–putamen and nucleus accumbens of rat brains by smoking
Bahk, J. Y., Li, S., Park, M. S., & Kim, M. O. (2002) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(02)00243-9 · Cited by 46
Differences in Nicotine-Induced Dopamine Release and Nicotine Pharmacokinetics Between Lewis and Fischer 344 Rats
Sziraki, I., Lipovac, M. N., Hashim, A. T., Sershen, H. W., Allen, D., Cooper, T. B., Czobor, P., & Lajtha, Á. (2001) · Neurochemical Research · doi:10.1023/a:1010979018217 · Cited by 45
Ligands for in vivo imaging of nicotinic receptor subtypes in Alzheimer brain
Sihver, W., Långström, B., & Nordberg, A. K. (2000) · Acta Neurologica Scandinavica · doi:10.1034/j.1600-0404.2000.00304.x · Cited by 45
Daily uplifts, hassles, stresses and cognitive failures: in cigarette smokers, abstaining smokers, and non-smokers
Parrott, A. C., & Kaye, F. J. (1999) · Behavioural Pharmacology · doi:10.1097/00008877-199911000-00010 · Cited by 43
Nicotine enhances cerebral glucose utilization in central components of the rat visual system
London, E. D., Dam, M., & Fanelli, R. J. (1988) · Brain Research Bulletin · doi:10.1016/0361-9230(88)90067-6 · Cited by 42
An acute dose of nicotine does not inhibit MAO B in baboon brain in vivo
Fowler, J. S., Volkow, N. D., Logan, J., Pappas, N. R., King, P. T., MacGregor, R. R., Shea, C. E., Garza, V., & Gatley, S. J. (1998) · Life Sciences · doi:10.1016/s0024-3205(98)00251-3 · Cited by 41
Lack of Stereoselectivity in Ability of Nicotine to Release Dopamine from Rat Synaptosomal Preparations
Connelly, M. S., & Littleton, J. M. (1983) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1983.tb00824.x · Cited by 41
2-[18F]F-A-85380
Chefer, S. I., Horti, A. G., Koren, A. O., Gündisch, D., Links, J. M., Kurian, V., Dannals, R. F., Mukhin, A. G., & London, E. D. (1999) · Neuroreport · doi:10.1097/00001756-199909090-00005 · Cited by 40
Bupropion as an aid to smoking cessation: a review of real-life effectiveness
Holmes, S., Zwar, N. A., Jimenez-Ruiz, C. A., Ryan, P. J., Browning, D., Bergmann, L., & Johnston, J. A. (2004) · International Journal of Clinical Practice · doi:10.1111/j.1368-5031.2004.00153.x · Cited by 37
Long‐lasting occupancy of central nicotinic acetylcholine receptors after smoking: a PET study in monkeys
Valette, H., Bottlaender, M., Dollé, F., Coulon, C., Ottaviani, M., & Syrota, A. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01502.x · Cited by 37
Craving for Alcohol and Drugs in Animals and Humans
Miller, N. S., & Goldsmith, R. J. (2001) · Journal of Addictive Diseases · doi:10.1300/j069v20n03_08 · Cited by 33
Imaging localised dynamic changes in the nucleus accumbens following nicotine withdrawal in rats
Shoaib, M. C., Lowe, A., & Williams, S. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.01.026 · Cited by 32
Nicotinic modulation of thalamocortical neurotransmission
Clarke, P. B. S. (2004) · Progress in brain research · doi:10.1016/s0079-6123(03)45017-6 · Cited by 31
A study of the acute effect of smoking on cerebral blood flow using 99mTc-ECD SPET
Yamamoto, Y., Nishiyama, Y., Monden, T., Satoh, K., & Ohkawa, M. (2003) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-003-1119-z · Cited by 29
Acute effects of cigarette smoking on cerebral oxygenation and hemodynamics
Terborg, C., Birkner, T., Schack, B., & Witte, O. W. (2002) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(02)00311-8 · Cited by 28
Nicotinic receptor binding sites in rat primary neuronal cells in culture: characterization and their regulation by chronic nicotine
Dávila‐García, M. I., Houghtling, R. A., Qasba, S. S., & Kellar, K. J. (1999) · Molecular Brain Research · doi:10.1016/s0169-328x(98)00344-1 · Cited by 28
Increase of glucose transporter densities (Glut1 and Glut3) during chronic administration of nicotine in rat brain
Duelli, R., Staudt, R., Grünwald, F., & Kuschinsky, W. (1998) · Brain Research · doi:10.1016/s0006-8993(97)01264-x · Cited by 27
Hostility differentiates the brain metabolic effects of nicotine
Fallon, J. H., Keator, D. B., Mbogori, J., Turner, J. A., & Potkin, S. G. (2004) · Cognitive Brain Research · doi:10.1016/j.cogbrainres.2003.10.003 · Cited by 27
Chronic treatments with tacrine and (−)-nicotine induce different changes of nicotinic and muscarinic acetylcholine receptors in the brain of aged rat
Zhang, X., Tian, J., Svensson, A., Gong, Z., Meyerson, B. J., & Nordberg, A. K. (2002) · Journal of Neural Transmission · doi:10.1007/s007020200030 · Cited by 25
Occupancy of brain nicotinic acetylcholine receptors by nicotine doses equivalent to those obtained when smoking a cigarette
Ding, Y., Volkow, N. D., Logan, J., Garza, V., Pappas, N. R., King, P. T., & Fowler, J. S. (2000) · Synapse · doi:10.1002/(sici)1098-2396(20000301)35:3 · Cited by 25
Effects of nicotine and chlorisondamine on cerebral glucose utilization in immobilized and freely‐moving rats
Marenco, T., Bernstein, S., Cumming, P. D., & Clarke, P. B. S. (2000) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703005 · Cited by 25
Activation of fronto-limbic system in the human brain by cigarette smoking: evaluated by a CBF measurement.
Nakamura, H. K., Tanaka, A., Nomoto, Y., Ueno, Y., & Nakayama, Y. (2000) · PubMed · Cited by 24
Reduction in cortical IMP-SPET tracer uptake with recent cigarette consumption in a young group of healthy males
Rourke, S. B., Dupont, R. M., Grant, I., Lehr, P. P., Lamoureux, G., Halpern, S. E., & Yeung, D. W. C. (1997) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/bf00881815 · Cited by 23
Characterization of the nicotinic ligand 2-[18F]fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine in vivo
Valette, H., Bottlaender, M., Dollé, F., Guenther, I., Coulon, C., Hinnen, F., Fuseau, C., Ottaviani, M., & Crouzel, C. (1998) · Life Sciences · doi:10.1016/s0024-3205(98)00573-6 · Cited by 23
A study on cerebral nicotine receptor distribution, blood flow, oxygen consumption, and other metabolic activities--a study on the effects of smoking on carotid and cerebral artery blood flow.
Kodaira, K., Fujishiro, K., Wada, T., Ken-ichi, M. A. I. E., SATOI, T., Tsukiyama, E., Fukumoto, T., Uchida, T., Yamazaki, S., & Okamura, T. (1993) · PubMed · Cited by 21
Cigarette Smoking and Addiction
Cohen, C., Pickworth, W. B., & Henningfield, J. E. (1991) · Clinics in Chest Medicine · doi:10.1016/s0272-5231(21)00818-2 · Cited by 20
Estimates of Smoking-Attributable Deaths at Ages 15–54, Motherless or Fatherless Youths, and Resulting Social Security Costs in the United States in 1994
Leistikow, B. N., Martin, D. C., & Milano, C. E. (2000) · Preventive Medicine · doi:10.1006/pmed.2000.0657 · Cited by 12
The effects of transdermal nicotine on inspection time
Thompson, J. C., Wilby, G., & Stough, C. K. K. (2002) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.377 · Cited by 11
Effects of smoking on regional cerebral blood flow in cerebral vascular disease patients and normal subjects.
Kubota, K., Yamaguchi, T., Fujiwara, T., & Matsuzawa, T. (1987) · The Tohoku Journal of Experimental Medicine · doi:10.1620/tjem.151.261 · Cited by 9
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Volkow (1999) · doi:10.1002/(sici)1098-2396(199901)31:1
Untitled work
(2000) · doi:10.1002/1098-2396(20001215)38:4

Research works printed but not linked: 3

Corrigall WA, Franklin KB, Coen KM, Clarke PB. The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine. Psychopharmacology (Berl) 1992;107:285–9. doi: 10.1007/BF02245149. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
Salokangas RKR, Vilkman H, Ilonen T, Taiminen T, Bergman J, Haaparanta M, Solin O, Alanen A, Syvalahti E, Hietala J. High levels of dopamine activity in the basal ganglia of cigarette smokers. American Journal of Psychiatry. 2000b;157:632–4. doi: 10.1176/appi.ajp.157.4.632. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
Stapleton JM, Gilson SF, Wong DF, Villemagne VL, Dannals RF, Grayson RF, Henningfield JE, London ED. Intravenous nicotine reduces cerebral glucose metabolism: a preliminary study. Neuropsychopharmacology. 2003b;28:765–72. doi: 10.1038/sj.npp.1300106. [DOI] [PubMed] [Google Scholar] · DOI

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Authors: BRODY, A.
Affiliations: University of California, Los Angeles (US)
Corresponding author: BRODY, A
ORCID: BRODY, A
Venue: Journal of Psychiatric Research
Publisher: Elsevier BV
Published: 2006-08
Volume: 40
Issue: 5
Pages: 404-418
ISSN: 0022-3956 (ISSN-L)
DOI: 10.1016/j.jpsychires.2005.04.012
PMC: PMC2876087
OpenAlex: W2047492603
Cited by: 207
References: 178
Citations by year: 2026: 5 · 2025: 4 · 2024: 9 · 2023: 9 · 2022: 2 · 2021: 7 · 2020: 8 · 2019: 7 · 2018: 11 · 2017: 6 · 2016: 8 · 2015: 15 · 2014: 12 · 2013: 14 · 2012: 12
FWCI: 7.62
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Psychiatric Research (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: U.S. Department of Veterans Affairs
National Institute on Drug Abuse (R01DA020872, R01 DA 15059, R01DA015059)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: tobacco dependence, smoking, nicotine, brain function, prefrontal cortex, thalamus, visual cortex, dopamine, nucleus accumbens, monoamine oxidase, nicotinic acetylcholine receptors, alpha4beta2 receptor, basal ganglia, attention, mood, anxiety, irritability
MeSH terms: Animals, Brain, Brain Mapping, Cognition, Dopamine, Humans, Personality, Receptors, Nicotinic, Smoking, Tobacco Use Disorder

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Functional brain imaging of tobacco use and dependence

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