Decellularization protocols of porcine heart valves differ importantly in efficiency of cell removal and susceptibility of the matrix to recellularization with human vascular cells

Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria.

Jaffe, E. A., Nachman, R., Becker, C. G., & Minick, C. (1973) · Journal of Clinical Investigation · doi:10.1172/jci107470 · Cited by 7,146 · see citing works

Infection of human cells by an endogenous retrovirus of pigs

Patience, C., Takeuchi, Y., & Weiss, R. A. (1997) · Nature Medicine · doi:10.1038/nm0397-282 · Cited by 1,140 · see citing works

Thromboembolic and bleeding complications in patients with mechanical heart valve prostheses.

Cannegieter, S. C., Rosendaal, F. R., & Briët, E. (1994) · Circulation · doi:10.1161/01.cir.89.2.635 · Cited by 1,072 · see citing works

Early failure of the tissue engineered porcine heart valve SYNERGRAFT™ in pediatric patients

Simon, P. (2003) · European Journal of Cardio-Thoracic Surgery · doi:10.1016/s1010-7940(03)00094-0 · Cited by 623 · see citing works

Tissue Engineering Heart Valves: Valve Leaflet Replacement Study in a Lamb Model

Shinoka, T., Breuer, C. K., Tanel, R. E., Zünd, G., Miura, T., Ma, P. X., Langer, R., Vacanti, J. P., & Mayer, J. E. (1995) · The Annals of Thoracic Surgery · doi:10.1016/0003-4975(95)00733-4 · Cited by 450 · see citing works

Creation Of Viable Pulmonary Artery Autografts Through Tissue Engineering

Shinoka, T., Shum‐Tim, D., Ma, P. X., Tanel, R. E., Isogai, N., Langer, R., Vacanti, J. P., & Mayer, J. E. (1998) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(98)70315-0 · Cited by 445 · see citing works

Tissue Engineering of Pulmonary Heart Valves on Allogenic Acellular Matrix Conduits : In Vivo Restoration of Valve Tissue

Steinhoff, G., Stock, U., Karim, N., Mertsching, H., Timke, A., Meliß, R. R., Pethig, K., Haverich, A., & Bader, A. (2000) · Circulation · doi:10.1161/01.cir.102.suppl_3.iii-50 · Cited by 352 · see citing works

Tissue engineering of heart valves – human endothelial cell seeding of detergent acellularized porcine valves1

Bader, A., Schilling, T., Teebken, O. E., Brandes, G., Herden, T., Steinhoff, G., & Haverich, A. (1998) · European Journal of Cardio-Thoracic Surgery · doi:10.1016/s1010-7940(98)00171-7 · Cited by 340 · see citing works

Expression of pig endogenous retrovirus by primary porcine endothelial cells and infection of human cells

Martin, U., Kiessig, V., Blusch, J., Haverich, A., von der Helm, K., Herden, T., & Steinhoff, G. (1998) · The Lancet · doi:10.1016/s0140-6736(98)07144-x · Cited by 311 · see citing works

Clinical autologous in vitro endothelialization of 153 infrainguinal ePTFE grafts

Meinhart, J., Deutsch, M., Fischlein, T., Howanietz, N., Fröschl, A., & Zilla, P. (2001) · The Annals of Thoracic Surgery · doi:10.1016/s0003-4975(01)02555-3 · Cited by 263 · see citing works

Long-term function of cryopreserved aortic homografts

Kirklin, J. K., Smith, D. R., Novick, W. M., Naftel, D. C., Kirklin, J. W., Pacifico, A. D., Nanda, N. C., Helmcke, F., & Bourge, R. C. (1993) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(19)33752-3 · Cited by 229 · see citing works

Tissue engineering of cardiac valve prostheses I: development and histological characterization of an acellular porcine scaffold.

Booth, C., Korossis, S. A., Wilcox, H. E., Watterson, K. G., Kearney, J. N., Fisher, J., & Ingham, E. (2002) · PubMed · Cited by 217 · see citing works

Tissue engineering of heart valves: in vitro experiences

Sodian, R., Hoerstrup, S. P., Sperling, J. S., Daebritz, S. H., Martin, D. P., Schöen, F. J., Vacanti, J. P., & Mayer, J. E. (2000) · The Annals of Thoracic Surgery · doi:10.1016/s0003-4975(00)01255-8 · Cited by 213 · see citing works

The α-gal epitope (Galα1-3Galβ1-4GlcNAc-R) in xenotransplantation

Galili, U. (2001) · Biochimie · doi:10.1016/s0300-9084(01)01294-9 · Cited by 212 · see citing works

Video-Assisted and Robotic Mitral Valve Surgery: Toward an Endoscopic Surgery

Chitwood, W. R. (1999) · Seminars in Thoracic and Cardiovascular Surgery · doi:10.1016/s1043-0679(99)70060-2 · Cited by 210 · see citing works

Cell-free arterial grafts: Morphologic characteristics of aortic isografts, allografts, and xenografts in rats

Allaire, É., Guettier, C., Bruneval, P., Plissonnier, D., & Michel, J. (1994) · Journal of Vascular Surgery · doi:10.1016/s0741-5214(94)70071-0 · Cited by 183 · see citing works

Engineering of human vascular aortic tissue based on a xenogeneic starter matrix.

Bader, A., Steinhoff, G., Strobl, K., Schilling, T., Brandes, G., Mertsching, H., Tsikas, D., Froelich, J., & Haverich, A. (2000) · PubMed · Cited by 126 · see citing works

The immunogenicity of the extracellular matrix in arterial xenografts

Allaire, É., Bruneval, P., Mandet, C., Becquemin, J., & Michel, J. (1997) · Surgery · doi:10.1016/s0039-6060(97)90267-1 · Cited by 101 · see citing works

Prospective clinical study with in vitro endothelial cell lining of expanded polytetrafluoroethylene grafts in crural repeat reconstruction

Magometschnigg, H. F., Kadletz, M., Vodrazka, M., Dock, W., Grimm, M. F., Grabenwöger, M., Minar, E., Staudacher, M., Fenzl, G., & Wolner, E. (1992) · Journal of Vascular Surgery · doi:10.1016/0741-5214(92)90192-b · Cited by 83 · see citing works

Damage of Porcine Aortic Valve Tissue Caused by the Surfactant Sodiumdodecylsulphate

Bodnár, E., Olsen, E. G. J., Florio, R., & Dobrin, J. S. (1986) · The Thoracic and Cardiovascular Surgeon · doi:10.1055/s-2007-1020381 · Cited by 67 · see citing works

Clinical Performance of Vascular Grafts Lined with Endothelial Cells

Bordenave, L., Rémy, M., Fernandez, P., Bareille, R., & Midy, D. (1999) · Endothelium · doi:10.3109/10623329909078494 · Cited by 66 · see citing works

Shear stress effects on bacterial adhesion, leukocyte adhesion, and leukocyte oxidative capacity on a polyetherurethane

Shive, M. S., Hasan, S. M., & Anderson, J. (1999) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(19990915)46:4 · Cited by 53 · see citing works

Tissue-Engineered Heart Valve Leaflets: An Effective Method of Obtaining Acellularized Valve Xenografts

Kim, W. G., Park, J. K., & Lee, W. Y. (2002) · The International Journal of Artificial Organs · doi:10.1177/039139880202500807 · Cited by 47 · see citing works

Confluent durable endothelialization of endarterectomized baboon aorta by early attachment of cultured endothelial cells

Schneider, P. A., Hanson, S. R., Price, T. M., & Harker, L. A. (1990) · Journal of Vascular Surgery · doi:10.1016/0741-5214(90)90234-2 · Cited by 43 · see citing works

Absence of PERV specific humoral immune response in baboons after transplantation of porcine cells or organs

Martin, U., Tacke, S. J., Simon, A. R., Schröder, C., Wiebe, K., Lapin, B. A., Haverich, A., Denner, J., & Steinhoff, G. (2002) · Transplant International · doi:10.1111/j.1432-2277.2002.tb00179.x · Cited by 29 · see citing works

Survival and bioprosthetic valve failure. Ten-year follow-up.

Kh, T., Ivanov, J., Weisel, R. D., Darcel, I. C., & Rakowski, H. (1989) · PubMed · Cited by 19 · see citing works

The hybrid xenograft/autograft bioprosthetic heart valve: In vivo evaluation of tissue extraction

Veselý, I., Noseworthy, R., & Pringle, G. A. (1995) · The Annals of Thoracic Surgery · doi:10.1016/0003-4975(95)00206-z · Cited by 17 · see citing works

Diadenosine Polyphosphates Are Largely Ineffective as Agonists at Natively Expressed P2Y1 and P2Y2 Receptors on Cultured Human Saphenous Vein Endothelial Cells

Conant, A. R., Fisher, M. J., McLennan, A. G., & Simpson, A. W. M. (2000) · Journal of Vascular Research · doi:10.1159/000054088 · Cited by 8 · see citing works

An overview of tissue and whole organ decellularization processes

Crapo, P. M., Gilbert, T. W., & Badylak, S. F. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.01.057 · Cited by 3,591 · see citing works

On the mechanisms of biocompatibility

Williams, D. F. (2008) · Biomaterials · doi:10.1016/j.biomaterials.2008.04.023 · Cited by 2,772 · see citing works

Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

Ott, H. C., Matthiesen, T. S., Goh, S.-K., Black, L. D., Kren, S. M., Netoff, T. I., & Taylor, D. A. (2008) · Nature Medicine · doi:10.1038/nm1684 · Cited by 2,650 · see citing works

Decellularization of tissues and organs

Gilbert, T. W., Sellaro, T. L., & Badylak, S. F. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.02.014 · Cited by 2,222 · see citing works

Reprint of: Extracellular matrix as a biological scaffold material: Structure and function

Badylak, S. F., Freytes, D. O., & Gilbert, T. W. (2015) · Acta Biomaterialia · doi:10.1016/j.actbio.2015.07.016 · Cited by 1,361 · see citing works

Whole-Organ Tissue Engineering: Decellularization and Recellularization of Three-Dimensional Matrix Scaffolds

Badylak, S. F., Taylor, D., & Uygun, K. (2011) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071910-124743 · Cited by 1,041 · see citing works

Decellularization Strategies for Regenerative Medicine: From Processing Techniques to Applications

Gilpin, A., & Yang, Y. (2017) · BioMed Research International · doi:10.1155/2017/9831534 · Cited by 742 · see citing works

Methods of tissue decellularization used for preparation of biologic scaffolds and in vivo relevance

Keane, T. J., Swinehart, I. T., & Badylak, S. F. (2015) · Methods · doi:10.1016/j.ymeth.2015.03.005 · Cited by 670 · see citing works

Consequences of ineffective decellularization of biologic scaffolds on the host response

Keane, T. J., Londono, R., Turner, N. J., & Badylak, S. F. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2011.10.054 · Cited by 613 · see citing works

Extracellular matrix-based biomaterial scaffolds and the host response

Aamodt, J. M., & Grainger, D. W. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.02.003 · Cited by 509 · see citing works

The effects of processing methods upon mechanical and biologic properties of porcine dermal extracellular matrix scaffolds

Reing, J. E., Brown, B. N., Daly, K. A., Freund, J. M., Gilbert, T. W., Hsiong, S. X., Huber, A., Kullas, K. E., Tottey, S., Wolf, M. T., et al. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.07.083 · Cited by 475 · see citing works

Decellularized Extracellular Matrix-based Bioinks for Engineering Tissue- and Organ-specific Microenvironments

Kim, B. S., Das, S., Jang, J., & Cho, D.-W. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00808 · Cited by 465 · see citing works

The use of decellularized adipose tissue to provide an inductive microenvironment for the adipogenic differentiation of human adipose-derived stem cells

Flynn, L. E. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.02.046 · Cited by 433 · see citing works

Effectiveness of three extraction techniques in the development of a decellularized bone–anterior cruciate ligament–bone graft

Woods, T., & Gratzer, P. F. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.05.066 · Cited by 375 · see citing works

Immunogenicity of decellularized extracellular matrix scaffolds: a bottleneck in tissue engineering and regenerative medicine

Kasravi, M., Ahmadi, A., Babajani, A., Mazloomnejad, R., Hatamnejad, M. R., Shariatzadeh, S., Bahrami, S., & Niknejad, H. (2023) · Biomaterials Research · doi:10.1186/s40824-023-00348-z · Cited by 316 · see citing works

Heart Valve Tissue Engineering

Veselý, I. (2005) · Circulation Research · doi:10.1161/01.res.0000185326.04010.9f · Cited by 309 · see citing works

Decellularized Allogeneic and Xenogeneic Tissue as a Bioscaffold for Regenerative Medicine: Factors that Influence the Host Response

Badylak, S. F. (2014) · Annals of Biomedical Engineering · doi:10.1007/s10439-013-0963-7 · Cited by 307 · see citing works

Tissue-Specific Decellularization Methods: Rationale and Strategies to Achieve Regenerative Compounds

Mendibil, U., Ruiz-Hernández, R., Retegi-Carrión, S., García‐Urkía, N., Olalde, B., & Abarrategi, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155447 · Cited by 302 · see citing works

Decellularization in Tissue Engineering and Regenerative Medicine: Evaluation, Modification, and Application Methods

Neishabouri, A., Soltani Khaboushan, A., Daghigh, F., Kajbafzadeh, A.-M., & Majidi Zolbin, M. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.805299 · Cited by 281 · see citing works

Perfusion decellularization of whole organs

Guyette, J. P., Gilpin, S. E., Charest, J. M., Tapias, L. F., Ren, X., & Ott, H. C. (2014) · Nature Protocols · doi:10.1038/nprot.2014.097 · Cited by 275 · see citing works

Detergent Decellularization of Heart Valves for Tissue Engineering: Toxicological Effects of Residual Detergents on Human Endothelial Cells

Cebotari, S., Tudorache, I., Jaekel, T., Hilfiker, A., Dorfman, S. E., Ternes, W., Haverich, A., & Lichtenberg, A. (2010) · Artificial Organs · doi:10.1111/j.1525-1594.2009.00796.x · Cited by 272 · see citing works

The use of high-hydrostatic pressure treatment to decellularize blood vessels

Funamoto, S., Nam, K., Kimura, T., Murakoshi, A., Hashimoto, Y., Niwaya, K., Kitamura, S., Fujisato, T., & Kishida, A. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.01.073 · Cited by 269 · see citing works

The impact of detergents on the tissue decellularization process: A ToF-SIMS study

White, L. J., Taylor, A. J., Faulk, D. M., Keane, T. J., Saldin, L. T., Reing, J. E., Swinehart, I. T., Turner, N. J., Ratner, B. D., & Badylak, S. F. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.12.033 · Cited by 268 · see citing works

Medical Application of Microbial Biopolyesters Polyhydroxyalkanoates

Wu, Q., Wang, Y., & Chen, G. (2009) · Artificial Cells Blood Substitutes and Biotechnology · doi:10.1080/10731190802664429 · Cited by 227 · see citing works

Peripheral nerve conduits: technology update

Hasirci, V., Arslantunali, D., Dursun, T., Yucel, D., & Hasirci, N. (2014) · Medical Devices Evidence and Research · doi:10.2147/mder.s59124 · Cited by 224 · see citing works

Comparison of Three Methods for the Derivation of a Biologic Scaffold Composed of Adipose Tissue Extracellular Matrix

Brown, B. N., Freund, J. M., Li, H., Rubin, J. P., Reing, J. E., Jeffries, E. M., Wolf, M. T., Tottey, S., Barnes, C. A., Ratner, B. D., et al. (2010) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2010.0342 · Cited by 223 · see citing works

Optimization and Critical Evaluation of Decellularization Strategies to Develop Renal Extracellular Matrix Scaffolds as Biological Templates for Organ Engineering and Transplantation

Caralt, M., Uzarski, J. S., Iacob, S., Obergfell, K. P., Berg, N., Bijonowski, B. M., Kiefer, K. M., Ward, H. H., Wandinger‐Ness, A., Miller, W. M., et al. (2014) · American Journal of Transplantation · doi:10.1111/ajt.12999 · Cited by 220 · see citing works

Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue-specific biomatrix scaffolds

Wang, Y., Cui, C.-B., Yamauchi, M., Miguez, P., Roach, M., Malavarca, R., Costello, J. M., Cardinale, V., Wauthier, E., Barbier, C., et al. (2011) · Hepatology · doi:10.1002/hep.24012 · Cited by 220 · see citing works

Biocompatibility evaluation of tissue-engineered decellularized scaffolds for biomedical application

Hussein, K. H., Park, K.-M., Kang, K.-S., & Woo, H.-M. (2016) · Materials Science and Engineering: C · doi:10.1016/j.msec.2016.05.068 · Cited by 218 · see citing works

Apple Derived Cellulose Scaffolds for 3D Mammalian Cell Culture

Modulevsky, D. J., Lefebvre, C., Haase, K., Al‐Rekabi, Z., & Pelling, A. E. (2014) · PLoS ONE · doi:10.1371/journal.pone.0097835 · Cited by 217 · see citing works

Aortic valve disease and treatment: The need for naturally engineered solutions

Butcher, J. T., Mahler, G. J., & Hockaday, L. A. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.01.008 · Cited by 211 · see citing works

Development of a Porcine Bladder Acellular Matrix with Well-Preserved Extracellular Bioactive Factors for Tissue Engineering

Yang, B., Zhang, Y., Zhou, L., Sun, Z., Zheng, J., Chen, Y., & Dai, Y. (2010) · Tissue Engineering Part C: Methods · doi:10.1089/ten.tec.2009.0311 · Cited by 206 · see citing works

Tissue-specific extracellular matrix accelerates the formation of neural networks and communities in a neuron-glia co-culture on a multi-electrode array

Lam, D., Enright, H. A., Cadena, J., Peters, S. K. G., Sales, A. P., Osburn, J. J., Soscia, D. A., Kulp, K. S., Wheeler, E. K., & Fischer, N. O. (2019) · Scientific Reports · doi:10.1038/s41598-019-40128-1 · Cited by 205 · see citing works

Extracellular Matrix-Based Biomaterials and Their Influence Upon Cell Behavior

Cramer, M. C., & Badylak, S. F. (2020) · Annals of Biomedical Engineering · doi:10.1007/s10439-019-02408-9 · Cited by 196 · see citing works

The host response to naturally-derived extracellular matrix biomaterials

Morris, A. H., Stamer, D. K., & Kyriakides, T. R. (2017) · Seminars in Immunology · doi:10.1016/j.smim.2017.01.002 · Cited by 180 · see citing works

Decellularized homologous tissue-engineered heart valves as off-the-shelf alternatives to xeno- and homografts

Dijkman, P. E., Driessen‐Mol, A., Frese, L., Hoerstrup, S. P., & Baaijens, F. F. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.03.015 · Cited by 172 · see citing works

Tissue Engineering of Heart Valves

Rieder, E., Seebacher, G., Kasimir, M., Eichmair, E., Winter, B., Dekan, B., Wolner, E., Simon, P., & Weigel, G. (2005) · Circulation · doi:10.1161/circulationaha.104.473629 · Cited by 171 · see citing works

Scaffolds for tissue engineering of cardiac valves

Jana, S., Tefft, B. J., Spoon, D. B., & Simari, R. D. (2014) · Acta Biomaterialia · doi:10.1016/j.actbio.2014.03.014 · Cited by 168 · see citing works

Bioprinting a cardiac valve

Jana, S., & Lerman, A. (2015) · Biotechnology Advances · doi:10.1016/j.biotechadv.2015.07.006 · Cited by 163 · see citing works

Matrix Alteration and Not Residual Sodium Dodecyl Sulfate Cytotoxicity Affects the Cellular Repopulation of a Decellularized Matrix

Gratzer, P. F., Harrison, R. D., & Woods, T. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.2975 · Cited by 160 · see citing works

Decellularization and Recellularization Technologies in Tissue Engineering

Fu, R., Wang, Y.-C., Liu, S., Shih, T.-R., Lin, H.-L., Chen, Y.-M., Sung, J.-H., Lu, C.-H., Wei, J.-R., Wang, Z.-W., et al. (2014) · Cell Transplantation · doi:10.3727/096368914x678382 · Cited by 158 · see citing works

Development and Characterization of an Acellular Human Pericardial Matrix for Tissue Engineering

Mirsadraee, S., Wilcox, H. E., Korossis, S. A., Kearney, J. N., Watterson, K. G., Fisher, J., & Ingham, E. (2006) · Tissue Engineering · doi:10.1089/ten.2006.12.763 · Cited by 157 · see citing works

Decellularized matrices for cardiovascular tissue engineering.

Moroni, F., & Mirabella, T. (2014) · Europe PMC (PubMed Central) · Cited by 149 · see citing works

Untitled work

(2006) · PubMed · Cited by 149 · see citing works

Tissue engineering of heart valves: advances and current challenges

Mol, A., Smits, A. I. P. M., Bouten, C. V. C., & Baaijens, F. F. (2009) · Expert Review of Medical Devices · doi:10.1586/erd.09.12 · Cited by 147 · see citing works

A Biodegradable, Acellular Xenogeneic Scaffold for Regeneration of the Vocal Fold Lamina Propria

Xu, C. C., Chan, R. W., & Tirunagari, N. (2007) · Tissue Engineering · doi:10.1089/ten.2006.0169 · Cited by 147 · see citing works

Decellularized extracellular matrix mediates tissue construction and regeneration

Liu, C., Pei, M., Li, Q., & Zhang, Y. (2021) · Frontiers of Medicine · doi:10.1007/s11684-021-0900-3 · Cited by 146 · see citing works

Decellularized Tissues for Wound Healing: Towards Closing the Gap Between Scaffold Design and Effective Extracellular Matrix Remodeling

Solarte-David, V. A., Güiza-Argüello, V. R., Arango-Rodríguez, M. L., Sossa, C., & Becerra‐Bayona, S. M. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.821852 · Cited by 146 · see citing works

The effect of source animal age upon extracellular matrix scaffold properties

Tottey, S., Johnson, S. A., Crapo, P. M., Reing, J. E., Zhang, L., Jiang, H., Medberry, C. J., Reines, B., & Badylak, S. F. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2010.09.006 · Cited by 138 · see citing works

Biocompatibility and Potential of Acellular Human Amniotic Membrane to Support the Attachment and Proliferation of Allogeneic Cells

Wilshaw, S.-P., Kearney, J., Fisher, J., & Ingham, E. (2008) · Tissue Engineering Part A · doi:10.1089/tea.2007.0145 · Cited by 137 · see citing works

In vitro re-endothelialization of detergent decellularized heart valves under simulated physiological dynamic conditions

Lichtenberg, A., Tudorache, I., Cebotari, S., Ringes‐Lichtenberg, S., Sturz, G., Hoeffler, K., Hurschler, C., Brandes, G., Hilfiker, A., & Haverich, A. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.03.047 · Cited by 135 · see citing works

Biologic Scaffolds

Costa, A., Naranjo, J. D., Londono, R., & Badylak, S. F. (2017) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a025676 · Cited by 135 · see citing works

Regulation of decellularized matrix mediated immune response

Chakraborty, J., Roy, S., & Ghosh, S. (2020) · Biomaterials Science · doi:10.1039/c9bm01780a · Cited by 130 · see citing works

TRITON‐X is most effective among three decellularization agents for ACL tissue engineering

Vavken, P., Joshi, S. M., & Murray, M. M. (2009) · Journal of Orthopaedic Research® · doi:10.1002/jor.20932 · Cited by 134 · see citing works

Bioactive scaffolds for tissue engineering: A review of decellularized extracellular matrix applications and innovations

Liu, J., Song, Q., Yin, W., Li, C., An, N., Le, Y., Wang, Q., Feng, Y., Hu, Y., & Wang, Y. (2025) · Exploration · doi:10.1002/exp.20230078 · Cited by 140 · see citing works

Method for perfusion decellularization of porcine whole liver and kidney for use as a scaffold for clinical‐scale bioengineering engrafts

Wang, Y., Bao, J., Wu, Q., Zhou, Y., Li, Y., Wu, X., Shi, Y., Li, L., & Bu, H. (2015) · Xenotransplantation · doi:10.1111/xen.12141 · Cited by 125 · see citing works

Recellularization of Decellularized Allograft Scaffolds in Ovine Great Vessel Reconstructions

Ketchedjian, A., Jones, A. L., Krueger, P. M., Robinson, E., Crouch, K., Wolfinbarger, L., & Hopkins, R. A. (2005) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2004.09.033 · Cited by 118 · see citing works

Recellularization of decellularized heart valves: Progress toward the tissue-engineered heart valve

VeDepo, M. C., Detamore, M. S., Hopkins, R. A., & Converse, G. L. (2017) · Journal of Tissue Engineering · doi:10.1177/2041731417726327 · Cited by 117 · see citing works

Flexor Tendon Tissue Engineering: Acellularization of Human Flexor Tendons with Preservation of Biomechanical Properties and Biocompatibility

Pridgen, B. C., Woon, C. Y.-L., Kim, M. Y., Thorfinn, J., Lindsey, D. P., Pham, H. M., & Chang, J. (2011) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2010.0457 · Cited by 116 · see citing works

Systematic in vitro comparison of decellularization protocols for blood vessels

Simsa, R., Padma, A. M., Heher, P., Hellström, M., Teuschl, A., Jenndahl, L., Bergh, N., & Fogelstrand, P. (2018) · PLOS ONE · doi:10.1371/journal.pone.0209269 · Cited by 115 · see citing works

Functional acellular matrix for tissue repair

Wang, B., Qinglai, T., Yang, Q., Li, M., Zeng, S., Yang, X., Xiao, Z., Tong, X., Lei, L., & Li, S. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100530 · Cited by 111 · see citing works

Effects of collagen fiber orientation on the response of biologically derived soft tissue biomaterials to cyclic loading

Sellaro, T. L., Hildebrand, D. K., Lu, Q., Vyavahare, N. R., Scott, M., & Sacks, M. S. (2006) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30871 · Cited by 110 · see citing works

Novel Utilization of Serum in Tissue Decellularization

Gui, L., Chan, S. A., Breuer, C. K., & Niklason, L. E. (2010) · Tissue Engineering Part C: Methods · doi:10.1089/ten.tec.2009.0120 · Cited by 109 · see citing works

A Review of Decellularized Extracellular Matrix Biomaterials for Regenerative Engineering Applications

Heath, D. E. (2019) · Regenerative Engineering and Translational Medicine · doi:10.1007/s40883-018-0080-0 · Cited by 108 · see citing works

Favorable effects of the detergent and enzyme extraction method for preparing decellularized bovine pericardium scaffold for tissue engineered heart valves

Yang, M., Chen, C., Wang, X., Zhu, Y., & Gu, Y. (2009) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.31409 · Cited by 108 · see citing works

Preparation and Characterization of Human Adipose Tissue-Derived Extracellular Matrix, Growth Factors, and Stem Cells: A Concise Review

Chun, S. Y., Lim, J. O., Lee, E. H., Han, M., Ha, Y., Lee, J. N., Kim, B. S., Park, M., Yeo, M., Jung, B., et al. (2019) · Tissue Engineering and Regenerative Medicine · doi:10.1007/s13770-019-00199-7 · Cited by 104 · see citing works

Biocompatibility of Acellular Human Pericardium

Mirsadraee, S., Wilcox, H. E., Watterson, K. G., Kearney, J. N., Hunt, J., Fisher, J., & Ingham, E. (2007) · Journal of Surgical Research · doi:10.1016/j.jss.2007.01.026 · Cited by 104 · see citing works

Using extracellular matrix for regenerative medicine in the spinal cord

Volpato, F. Z., Führmann, T., Migliaresi, C., Hutmacher, D. W., & Dalton, P. D. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.03.057 · Cited by 103 · see citing works

Functional Characterization of Detergent-Decellularized Equine Tendon Extracellular Matrix for Tissue Engineering Applications

Youngstrom, D. W., Barrett, J. G., Jose, R. R., & Kaplan, D. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064151 · Cited by 102 · see citing works

The decellularized porcine heart valve matrix in tissue engineering

Kasimir, M., Weigel, G., Sharma, J., Rieder, E., Seebacher, G., Wolner, E., & Simon, P. (2005) · Thrombosis and Haemostasis · doi:10.1160/th05-01-0025 · Cited by 101 · see citing works

Mechanical Evaluation of Decellularized Porcine Thoracic Aorta

Zou, Y. F., & Zhang, Y. (2011) · Journal of Surgical Research · doi:10.1016/j.jss.2011.03.070 · Cited by 100 · see citing works

Bone Marrow Niches of Hematopoietic Stem and Progenitor Cells

Kandarakov, O. F., Belyavsky, A. V., & Semenova, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23084462 · Cited by 97 · see citing works

The surface molecular functionality of decellularized extracellular matrices

Barnes, C. A., Brison, J., Michel, R., Brown, B. N., Castner, D. G., Badylak, S. F., & Ratner, B. D. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.09.007 · Cited by 97 · see citing works

Tracheal Replacement With Cryopreserved, Decellularized, or Glutaraldehyde-Treated Aortic Allografts

Seguin‐Givelet, A., Radu, D. M., Holder‐Espinasse, M., Bruneval, P., Fialaire, A., Duterque‐Coquillaud, M., Carpentier, A., & Martinod, E. (2009) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2008.11.038 · Cited by 97 · see citing works

Tissue engineering of heart valves using decellularized xenogeneic or polymeric starter matrices

Schmidt, D., Stock, U. A., & Hoerstrup, S. P. (2007) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2007.2131 · Cited by 92 · see citing works

Decellularized Human Kidney Cortex Hydrogels Enhance Kidney Microvascular Endothelial Cell Maturation and Quiescence

Nagao, R. J., Xu, J. H., Luo, P., Xue, J., Wang, Y., Kotha, S. S., Zeng, W., Fu, X., Himmelfarb, J., & Zheng, Y. Y. (2016) · Tissue Engineering Part A · doi:10.1089/ten.tea.2016.0213 · Cited by 90 · see citing works

Tissue and organ decellularization in regenerative medicine

Damodaran, R. G., & Vermette, P. (2018) · Biotechnology Progress · doi:10.1002/btpr.2699 · Cited by 90 · see citing works

Effect of Decellularization Protocol on the Mechanical Behavior of Porcine Descending Aorta

Fitzpatrick, J. C., Clark, P., & Capaldi, F. M. (2010) · International Journal of Biomaterials · doi:10.1155/2010/620503 · Cited by 84 · see citing works

Decellularized Extracellular Matrix Scaffolds for Cardiovascular Tissue Engineering: Current Techniques and Challenges

Barbulescu, G. I., Bojin, F. M., Ordodi, V. L., Goje, I.-D., Barbulescu, A. S., & Păunescu, V. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232113040 · Cited by 83 · see citing works

Decellularized bovine intervertebral disc as a natural scaffold for xenogenic cell studies

Chan, L. K. Y., Leung, V., Tam, V., Lu, W. W., Sze, K. Y., & Cheung, K. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2012.09.005 · Cited by 81 · see citing works

Transplantation material bovine pericardium: biomechanical and immunogenic characteristics after decellularization vs. glutaraldehyde‐fixing

Hülsmann, J., Grün, K., Amouri, S. E., Barth, M., Hornung, K., Holzfuß, C., Lichtenberg, A., & Akhyari, P. (2012) · Xenotransplantation · doi:10.1111/j.1399-3089.2012.00719.x · Cited by 81 · see citing works

Design and Characterization of Tissue-Specific Extracellular Matrix-Derived Microcarriers

Turner, A. E. B., & Flynn, L. E. (2011) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2011.0246 · Cited by 79 · see citing works

Decellularized breast matrix as bioactive microenvironment for in vitro three‐dimensional cancer culture

Jin, Q., Liu, G., Li, S., Yuan, H., Yun, Z., Zhang, W., Zhang, S., Dai, Y., & Yu-zhen, M. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26782 · Cited by 79 · see citing works

Tissue engineering on matrix: future of autologous tissue replacement

Weber, B., Emmert, M. Y., Schoenauer, R., Brokopp, C. E., Baumgartner, L., & Hoerstrup, S. P. (2011) · Seminars in Immunopathology · doi:10.1007/s00281-011-0258-8 · Cited by 78 · see citing works

Generation and characterization of a human acellular meniscus scaffold for tissue engineering

Sandmann, G. H., Eichhorn, S., Vogt, S., Adamczyk, C., Aryee, S., Hoberg, M., Milz, S., Imhoff, A. B., & Tischer, T. (2008) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.32269 · Cited by 75 · see citing works

Development of a novel human recellularized endometrium that responds to a 28-day hormone treatment†

Olalekan, S. A., Burdette, J. E., Getsios, S., Woodruff, T. K., & Kim, J. J. (2017) · Biology of Reproduction · doi:10.1093/biolre/iox039 · Cited by 73 · see citing works

Biomechanical characterization of decellularized and cross-linked bovine pericardium.

Oswal, D., Korossis, S., Mirsadraee, S., Wilcox, H., Watterson, K. G., Fisher, J., & Ingham, E. (2007) · PubMed · Cited by 72 · see citing works

Biomaterials to Prevascularize Engineered Tissues

Tian, L., & George, S. C. (2011) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-011-9301-3 · Cited by 72 · see citing works

In vitro analysis of an allogenic scaffold for tissue‐engineered meniscus replacement

Maier, D., Braeun, K., Steinhauser, E., Ueblacker, P., Oberst, M., Kreuz, P., Roos, N., Martinek, V., & Imhoff, A. B. (2007) · Journal of Orthopaedic Research® · doi:10.1002/jor.20405 · Cited by 69 · see citing works

The use of three-dimensional nanostructures to instruct cells to produce extracellular matrix for regenerative medicine strategies

Schenke‐Layland, K., Rofail, F., Heydarkhan, S., Gluck, J. M., Ingle, N. P., Angelis, E., Choi, C., MacLellan, W. R., Beygui, R. E., Shemin, R. J., et al. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.05.033 · Cited by 67 · see citing works

Different approaches to heart valve decellularization: A comprehensive overview of the past 30 years

Naso, F., & Gandaglia, A. (2017) · Xenotransplantation · doi:10.1111/xen.12354 · Cited by 66 · see citing works

Technological and structural aspects of scaffold manufacturing for cultured meat: recent advances, challenges, and opportunities

Kumar, A., Sood, A., & Han, S. S. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2132206 · Cited by 66 · see citing works

Effects of nucleus pulposus cell-derived acellular matrix on the differentiation of mesenchymal stem cells

Yuan, M., Yeung, C. W., Li, Y. Y., Diao, H., Cheung, K., Chan, D. T.-M., Cheah, K. S. E., & Chan, B. P. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.02.004 · Cited by 66 · see citing works

Optimizing Perfusion-Decellularization Methods of Porcine Livers for Clinical-Scale Whole-Organ Bioengineering

Wu, Q., Bao, J., Zhou, Y., Wang, Y., Du, Z., Shi, Y., Li, L., & Bu, H. (2015) · BioMed Research International · doi:10.1155/2015/785474 · Cited by 66 · see citing works

Approaches to heart valve tissue engineering scaffold design

Brody, S., & Pandit, A. S. (2007) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.30763 · Cited by 66 · see citing works

Medical applications of biopolyesters polyhydroxyalkanoates

Chen, G., & Wang, Y. (2013) · Chinese Journal of Polymer Science · doi:10.1007/s10118-013-1280-1 · Cited by 64 · see citing works

Nerve Repair Using Decellularized Nerve Grafts in Rat Models. A Review of the Literature

Lovati, A. B., D’Arrigo, D., Odella, S., Tos, P., Geuna, S., & Raimondo, S. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00427 · Cited by 64 · see citing works

Performance and Morphology of Decellularized Pulmonary Valves Implanted in Juvenile Sheep

Quinn, R. W., Hilbert, S. L., Bert, A. A., Drake, B. W., Bustamante, J. A., Fenton, J., Moriarty, S. J., Neighbors, S., Lofland, G. K., & Hopkins, R. A. (2011) · The Annals of Thoracic Surgery · doi:10.1016/j.athoracsur.2011.03.039 · Cited by 62 · see citing works

Process-induced extracellular matrix alterations affect the mechanisms of soft tissue repair and regeneration

Sun, W. Q., Xu, H. M., Sandor, M., & Lombardi, J. (2013) · Journal of Tissue Engineering · doi:10.1177/2041731413505305 · Cited by 62 · see citing works

The biomechanical behavior and host response to porcine-derived small intestine submucosa, pericardium and dermal matrix acellular grafts in a rat abdominal defect model

Zhang, J., Wang, G. Y., Xiao, Y. P., Fan, L. Y., & Wang, Q. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.06.016 · Cited by 61 · see citing works

Comparison of Different Decellularization Procedures of Porcine Heart Valves

Kasimir, M., Rieder, E., Seebacher, G., Silberhumer, G. R., Wolner, E., Weigel, G. J., & Simon, P. (2003) · The International Journal of Artificial Organs · doi:10.1177/039139880302600508 · Cited by 213 · see citing works

[Effect of trypsin and Triton-X 100 for decellularization of porcine aortic heart valves].

Wang, K.-X., Zhang, J.-F., Zhan, Q.-P., & Jian, X. (2005) · PubMed · Cited by 6 · see citing works

Studies on different decellularization procedures for heart valve tissue engineering

Zhang, L. (2007) · International Journal of Cardiovascular Disease

Notice of Correction

(2015) · Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/j.jtcvs.2015.04.012 · Cited by 1 · see citing works

Decellularized porcine aortic valve scaffolds created by different decellularization protocols: a comparison of their histological,biomechanical,and biocompatible characteristics

Liu, Y. (2007) · Academic Journal of Second Military Medical University