Cited by 162Eating Disorders and BehaviorsRegulation of Appetite and ObesityNutrition, Health and Food Behavior

The DOI matches its Crossref record; 86 of the 86 references it cites were found in a registry or an index; none of the 61 sources its claims cite is checked for support yet.

Caloric deprivation increases responsivity of attention and reward brain regions to intake, anticipated intake, and images of palatable foods

Open access

Stice, Eric, Burger, Kyle, Yokum, Sonja·2013·NeuroImage

DOI 10.1016/j.neuroimage.2012.11.028PMC PMC3693571

Open this paper in CoChat — free account

Abstract

Dietary restraint theoretically increases risk for binge eating, but prospective and experimental studies have produced contradictory findings, apparently because dietary restraint scales do not identify individuals who are reducing caloric intake. Yet, experimentally manipulated caloric deprivation increases responsivity of brain regions implicated in attention and reward to food images, which may contribute to binge eating. We tested whether self-imposed acute and longer-term caloric restriction increases responsivity of attention and reward regions to images, anticipated receipt, and receipt of palatable food using functional magnetic resonance imaging among female and male adolescents (Study 1 n=34; Study 2 n=51/81). Duration of acute caloric deprivation correlated positively with activation in regions implicated in attention, reward, and motivation in response to images, anticipated receipt, and receipt of palatable food (e.g., anterior cingulate cortex, orbitofrontal cortex, putamen, and precentral gyrus respectively). Youth in a longer-term negative energy balance likewise showed greater activation in attention (anterior cingulate cortex, ventral medial prefrontal cortex), visual processing (superior visual cortex), reward (caudate) and memory (hippocampus) regions in response to receipt and anticipated receipt of palatable food relative to those in neutral or positive energy balance. Results confirm that self-imposed caloric deprivation increases responsivity of attention, reward, and motivation regions to food, which may explain why caloric deprivation weight loss diets typically do not produce lasting weight loss.

AI snapshot

Written from the paper’s full text.

TL;DR

In two fMRI studies of adolescents, longer self-imposed caloric deprivation and a 2-week negative energy balance were associated with greater responsivity of attention, reward, and motivation brain regions to palatable food images, anticipated milkshake receipt, and milkshake receipt. The authors argue this may help explain why caloric-deprivation weight-loss diets often do not produce lasting weight loss.

Key findings

Study 1 (N = 34 female adolescents; mean deprivation 7.8 ± 4.6 hours, range 1–16): duration of caloric deprivation correlated positively with left OFC activation for appetizing > unappetizing food pictures and right precentral gyrus activation for appetizing > water pictures; no significant effects emerged for reverse contrasts or quadratic relations.
Study 2 acute deprivation (n = 51; mean 6.9 ± 3.7 hours, range 3–22.5): hours since last caloric intake correlated positively with activation during milkshake cue > tasteless cue in regions including MTG, precentral gyrus, medial SFG, lingual gyrus, dlPFC, dorsal ACC, MFG, IOG, vlPFC, parahippocampal gyrus, putamen, cerebellum, thalamus, and MOG; for milkshake receipt > tasteless receipt, it correlated positively with left mid insula.
Study 2 longer-term energy balance: the negative energy balance group (≥1 kg loss; n = 27; mean −1.5 ± 0.5 kg) showed greater activation than the positive energy balance group (n = 23; mean +1.7 ± 0.9 kg) in left precuneus, left mPFC, and right ventral ACC for anticipated receipt, and in left caudate and right precentral gyrus for receipt; versus the energy stable group (n = 31; mean −0.01 ± 0.08 kg), it showed greater activation in left cuneus, left dlPFC, and left PCC for anticipated receipt, and bilateral caudate, right hippocampus, left MOG, and left fusiform gyrus for receipt.
Dutch Restrained Eating Scale scores were not significantly related to hours of food deprivation in Study 1 (p = 0.98; r = 0.004) or Study 2 (p = 0.46; r = 0.10), and did not differ across energy balance groups (p = 0.92).

Methods

Two fMRI studies in adolescents. Study 1 included 34 healthy female adolescents (M age = 15.5 ± 0.9, BMI = 24.6 ± 5.6). Study 2 included 162 adolescent males and females (M age = 15.3 ± 1.07, BMI = 20.8 ± 1.90), but analyses used 51 participants with data on pre-scan caloric deprivation and 81 participants meeting weight-change criteria.
Study 1 used a food-picture paradigm: participants rated 103 food pictures, then viewed their 40 most appetizing, 40 least appetizing, and 40 water pictures; contrasts were appetizing > unappetizing and appetizing > water, regressed on hours since last dietary intake.
Study 2 used a milkshake receipt/anticipation paradigm with chocolate milkshake versus calorie-free tasteless solution; contrasts were milkshake receipt > tasteless receipt and milkshake cue > tasteless cue, regressed on hours since last caloric intake and compared across negative, stable, and positive energy balance groups based on 2-week weight change (lost ≥1 kg, remained within 0.1 kg, gained ≥1 kg). Imaging used SPM8 with whole-brain cluster-level correction (p < 0.001, k ≥ 11, corrected p < 0.05).

Limitations

The paper states: there was no way to confirm that the negative energy balance group consumed fewer calories than needed on the actual scan day; only one palatable food was tested and it was a beverage, so generalization to solid foods is cautious; participants were adolescents, so results may not generalize to adults; and sample sizes, though larger than many imaging studies, were still moderate and may have limited power and generalizability.
Evident from the text: the acute-deprivation analyses in Study 2 used only 51 of 162 participants because deprivation data were not collected for all; Study 1 included only females while Study 2 included both sexes; and the acute-deprivation findings are correlational, based on self-reported hours since last intake rather than experimentally manipulated deprivation.

Model-written summary. Check it against the paper before relying on it.

Integrity signals

Registry

Crossref · 10.1016/j.neuroimage.2012.11.028

Cites

86 of 86 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

0 of 61 cited sources checked · 0 supported · 0 flagged

A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Youth in a longer-term negative energy balance likewise showed greater activation in attention (anterior cingulate cortex, ventral medial prefrontal cortex), visual processing (superior visual cortex), reward (caudate) and memory (hippocampus) regions in response to receipt and anticipated receipt of palatable food relative to those in neutral or positive energy balance.”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > Abstract
Load-bearingStrength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
- Rests on an assumption: Weight change over the 2-week period is a valid index of negative, neutral, or positive energy balance.
- Rests on an assumption: BOLD response in attention and reward regions reflects responsivity or reward value to food.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Duration of acute caloric deprivation correlated positively with activation in regions implicated in attention, reward, and motivation in response to images, anticipated receipt, and receipt of palatable food (e.g., anterior cingulate cortex, orbitofrontal cortex, putamen, and precentral gyrus respectively).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > Abstract
Load-bearingStrength:plain· not yet calibratedCausal:correlational· not yet calibratedn = 34
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
- Rests on an assumption: Number of hours since last caloric intake is a valid measure of acute caloric deprivation.
- Rests on an assumption: BOLD response in attention and reward regions reflects responsivity or reward value to food.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In the appetizing food > unappetizing food contrast, duration of caloric deprivation was positively related to activity in the left OFC (Figure 1A).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 3.1 Results
Load-bearingStrength:plain· not yet calibratedCausal:correlational· not yet calibratedn = 34
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
- Rests on an assumption: Number of hours since last caloric intake is a valid measure of acute caloric deprivation.
- Rests on an assumption: BOLD response in attention and reward regions reflects responsivity or reward value to food.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In the appetizing food > water contrast, duration of caloric deprivation was positively related to activity in the right precentral gyrus (Figure 1B).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 3.1 Results
Strength:plain· not yet calibratedCausal:correlational· not yet calibratedn = 34
Tests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passes
- Rests on an assumption: Number of hours since last caloric intake is a valid measure of acute caloric deprivation.
- Rests on an assumption: BOLD response in attention and reward regions reflects responsivity or reward value to food.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In the milkshake receipt > tasteless receipt contrast, hours of caloric deprivation correlated positively with activation in the left mid insula (Table 2).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 3.1 Results
Load-bearingStrength:plain· not yet calibratedCausal:correlational· not yet calibratedn = 51
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
- Rests on an assumption: Number of hours since last caloric intake is a valid measure of acute caloric deprivation.
- Rests on an assumption: BOLD response in attention and reward regions reflects responsivity or reward value to food.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In the milkshake receipt > tasteless receipt contrast, the negative energy balance group showed greater activation in left caudate and right precentral gyrus relative to the positive energy balance group (Table 3).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 3.1 Results
Load-bearingStrength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
- Rests on an assumption: Weight change over the 2-week period is a valid index of negative, neutral, or positive energy balance.
- Rests on an assumption: BOLD response in attention and reward regions reflects responsivity or reward value to food.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The negative energy balance group also showed greater activation in the bilateral caudate, right hippocampus, left MOG, and left fusiform gyrus relative to the energy stable group (Table 3).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 3.1 Results
Load-bearingStrength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
- Rests on an assumption: Weight change over the 2-week period is a valid index of negative, neutral, or positive energy balance.
- Rests on an assumption: BOLD response in attention and reward regions reflects responsivity or reward value to food.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Participants in the negative energy balance group (≥ 1kg in weight loss; n = 27) showed a mean weight change of −1.5 ± 0.5kg (range −3.0- −1.0kg) over the 2-week period.”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 3.1 Results
Load-bearingStrength:plain· not yet calibratedn = 27
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
- Rests on an assumption: Weight change over the 2-week period is a valid index of negative, neutral, or positive energy balance.
In the paper
“dietary restraint scores correlated positively with activation in the OFC and dlPFC in response to milkshake receipt”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Burger & Stice, 2011 source
Strength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passes
In the paper
“but did not correlate with activation in response to anticipated receipt of milkshake or pictures of palatable food (Burger & Stice, 2011).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Burger & Stice, 2011 source
Strength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passes
None of the sources cited for this claim have been checked yet.
In the paper
“Consistent with dietary restraint theory, females with high versus low scores on dietary restraint scales are at greater risk for future onset of binge eating, bulimic symptoms, and bulimia nervosa”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Neumark-Sztainer et al., 2006 source
- Not checked yetcites Killen et al., 1996 source
- Not checked yetcites Stice, Davis, Miller, & Marti, 2008a
Strength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passes
None of the sources cited for this claim have been checked yet.
In the paper
“Individuals with high versus low scores on various dietary restraint scales do not consume fewer calories according to objective measures of intake during single eating episodes”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Hetherington et al., 2000 source
- Not checked yetcites Ouwens, van Strien, & van der Staak, 2003
- Not checked yetcites Stice, Fisher, & Lowe 2004
Load-bearingStrength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Results confirm that self-imposed caloric deprivation increases responsivity of attention, reward, and motivation regions to food”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > Abstract
Load-bearingStrength:boosted· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
- Rests on an assumption: Weight change over the 2-week period is a valid index of negative, neutral, or positive energy balance.
- Rests on an assumption: Number of hours since last caloric intake is a valid measure of acute caloric deprivation.
- Rests on an assumption: BOLD response in attention and reward regions reflects responsivity or reward value to food.
- Rests on an assumption: Caloric deprivation weight loss diets typically do not produce lasting weight loss.
None of the sources cited for this claim have been checked yet.
In the paper
“Yet, experimentally manipulated caloric deprivation increases responsivity of brain regions implicated in attention and reward to food images”
- Also stated in: § 1. Introduction · hedged
  “functional magnetic resonance imaging (fMRI) experiments indicate that activation in regions that have been implicated in attention (anterior cingulate cortex), reward valuation (amygdala), memory (hippocampus), and homeostatic feeding (hypothalamus) was significantly greater in response to pictures of palatable foods versus non-food control images after caloric deprivation versus a no deprivation”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > Abstract
What the sources say
- Not checked yetcites Fuhrer et al., 2008 source
- Not checked yetcites LaBar et al., 2001 source
- Not checked yetcites Leidy et al., 2011 source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“apparently because dietary restraint scales do not identify individuals who are reducing caloric intake”
- Also stated in: § 1. Introduction · hedged
  “It appears that these inconsistent findings emerged because the prospective studies used dietary restraint scales that do not identify individuals who are reducing caloric intake”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > Abstract
Load-bearingStrength:hedged· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
In the paper
“One experiment found a greater response in attention (posterior cingulate cortex) and reward (amygdala, orbitofrontal cortex [OFC], insula, and striatum) regions to pictures of high-calorie versus low-calorie foods after a period of caloric deprivation versus a non-deprivation condition”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Goldstone et al., 2009 source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
In the paper
“dieting efforts are typically several weeks in duration (Williamson, Serdula, Anda, Levy, & Byers, 1992).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Williamson, Serdula, Anda, Levy, & Byers, 1992
Load-bearingStrength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
None of the sources cited for this claim have been checked yet.
In the paper
“activation in regions that have been implicated in attention (anterior cingulate cortex), reward valuation (amygdala), memory (hippocampus), and homeostatic feeding (hypothalamus) was significantly greater in response to pictures of palatable foods versus non-food control images after caloric deprivation versus a no deprivation condition”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Fuhrer et al., 2008 source
- Not checked yetcites LaBar et al., 2001 source
- Not checked yetcites Leidy et al., 2011 source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
In the paper
“suggesting that caloric deprivation increases the reward value of high-calorie foods more than low-calorie foods.”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Goldstone et al., 2009 source
Load-bearingStrength:hedged· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
In the paper
“Another experiment found that there was greater response in the primary gustatory cortex (anterior insula, frontal operculum) and regions associated with reward (dorsolateral prefrontal cortex, medial prefrontal cortex) in response to intake of food (chocolate milk, chicken soup) after caloric deprivation versus a non-deprivation condition”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Uher et al., 2006 source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
None of the sources cited for this claim have been checked yet.
In the paper
“The evidence that elective caloric restriction in the present studies was associated with greater responsivity of attention and reward regions to palatable food images, anticipated receipt of palatable food, and receipt of palatable food more broadly extend findings from caloric deprivation experiments.”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Fuhrer et al., 2008 source
- Not checked yetcites Goldstone et al., 2009 source
- Not checked yetcites Leidy et al, 2011 source
Load-bearingStrength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
In the paper
“In vivo dialysis experiments show higher food-induced DA release in fasted versus satiated rats (Wilson et al., 1995).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Wilson et al., 1995 source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
In the paper
“Accumbens DA levels have been shown to increase in response to caloric intake more following longer versus shorter caloric deprivation periods (Yoshida et al., 1992)”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Yoshida et al., 1992 source
Load-bearingStrength:boosted· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
In the paper
“and in response to caloric deprivation weight loss diets versus baseline (Avena et al., 2008).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Avena et al., 2008 source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
In the paper
“Intracerebroventricular injection of the DR2 agonist quinpirole produced a more pronounced striatal neuronal activation in caloric restricted rats versus ad lib fed controls (Carr et al., 2003).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Carr et al., 2003 source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
None of the sources cited for this claim have been checked yet.
In the paper
“The present findings may also explain why people who attempt to diet do not typically succeed per objective measures of caloric intake (e.g., Hetherington et al., 2000; Stice et al., 2004; Sysko et al., 2007).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Hetherington et al., 2000 source
- Not checked yetcites Stice et al., 2004 source
- Not checked yetcites Sysko et al., 2007 source
Load-bearingStrength:hedged· not yet calibratedCausal:conditional· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes

Probably not a substantial claim. 30
It may state two separate claims as one. 22
The quote only partly states this claim. 1

A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In the milkshake cue > tasteless solution cue contrast, hours of caloric deprivation correlated positively with activation in the right hemisphere in the middle temporal gyrus (MTG), precentral gyrus, medial superior frontal gyrus (medial SFG), lingual gyrus, dorsolateral prefrontal cortex (dlPFC, Figure 1C), dorsal anterior cingulate cortex (dorsal ACC), and middle frontal gyrus (MFG)”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 3.1 Results
Load-bearingStrength:plain· not yet calibratedCausal:correlational· not yet calibratedn = 51
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
The quote only partly states this claim.
- Rests on an assumption: Number of hours since last caloric intake is a valid measure of acute caloric deprivation.
- Rests on an assumption: BOLD response in attention and reward regions reflects responsivity or reward value to food.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Those in the positive energy balance group (≥ 1kg in weight gain; n = 23) showed a mean weight gain of 1.7 ± 0.9kg (range 1.1 - 5.6kg) over the 2-week period.”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 3.1 Results
Strength:plain· not yet calibratedn = 23
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
- Rests on an assumption: Weight change over the 2-week period is a valid index of negative, neutral, or positive energy balance.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In the milkshake cue > tasteless solution cue contrast, participants in the negative energy balance group showed greater activation in the left precuneus, left medial prefrontal cortex (mPFC), and right ventral ACC relative to the positive energy balance group and greater activation in the left cuneus, left dlPFC, and left posterior cingulate cortex (PCC) relative to the energy stable group (Table”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 3.1 Results
Load-bearingStrength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
- Rests on an assumption: Weight change over the 2-week period is a valid index of negative, neutral, or positive energy balance.
- Rests on an assumption: BOLD response in attention and reward regions reflects responsivity or reward value to food.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Participants in the energy stable group (remained within 0.1kg, n = 31) showed a trivial increase in mean weight (−0.01 ± 0.08kg; range −0.1 - 0.1kg).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 3.1 Results
Strength:plain· not yet calibratedn = 31
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
- Rests on an assumption: Weight change over the 2-week period is a valid index of negative, neutral, or positive energy balance.
None of the sources cited for this claim have been checked yet.
In the paper
“Dietary restraint theoretically increases risk for binge eating”
- Also stated in: § 1. Introduction · plain
  “Theorists posit that dietary restraint increases risk for onset and maintenance of binge eating and bulimia nervosa (Fairburn, 1997; Polivy & Herman, 1985).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > Abstract
What the sources say
- Not checked yetcites Fairburn, 1997
- Not checked yetcites Polivy & Herman, 1985 source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
Probably not a substantial claim.
None of the sources cited for this claim have been checked yet.
In the paper
“increases in bulimic symptoms (Johnson & Wardle, 2005; Stice, 2001; Wertheim, Koerner, & Paxton, 2001).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Johnson & Wardle, 2005
- Not checked yetcites Stice, 2001 source
- Not checked yetcites Wertheim, Koerner, & Paxton, 2001
Strength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“some individuals may engage in true caloric restriction, which does increase risk for binge eating (Stice et al., 2010).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Stice et al., 2010 source
Load-bearingStrength:hedged· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“However, randomized trials find that assignment to energy-deficit weight loss interventions versus waitlist control conditions results in significant decreases in binge eating for healthy young adults”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Groesz & Stice, 2007
- Not checked yetcites Presnell & Stice, 2003
- Not checked yetcites Goodrick, Poston, Kimball, Reeves & Foreyt, 1998
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“rats randomized to extreme caloric deprivation conditions (in which they lost 7% - 20% of their body mass) eat significantly more calories during ad lib feeding and show a preference for high-fat foods immediately after the deprivation period relative to non-deprived rats”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Hagan, Chandler, Wauford, Rybak, & Oswald, 2003
- Not checked yetcites Lucas & Sclafani, 1992
- Not checked yetcites Ogawa et al., 2005 source
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
In the paper
“Because findings did not change when this covariate was included, results from analyses that did not include this covariate are reported.”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 2.6 Imaging acquisition, preprocessing and analysis
What the sources say
- Not checked yetcites Dreher et al., 2007 source
Strength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“potentially because of the small samples used in these studies (Ns = 10 to 20).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Siep et al., 2009 source
- Not checked yetcites Uher et al., 2006 source
Strength:hedged· not yet calibratedCausal:conditional· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“though null effects also emerged (Siep et al., 2009; Uher et al., 2006)”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Siep et al., 2009 source
- Not checked yetcites Uher et al., 2006 source
Strength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“humans randomized to periods of caloric deprivation work longer on operant tasks to earn high-calorie snack foods and eat more snack foods than non-deprived controls”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites Cameron, Goldfield, Cyr, & Doucet, 2008
- Not checked yetcites Epstein et al., 2003 source
- Not checked yetcites Raynor & Epstein, 2003
Load-bearingStrength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“This scale has shown internal consistency (α’s range from .93 to .95) and temporal reliability (2-week test-retest r = .82; Stice, et al., 2004; van Strien et al., 1986).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 2.3 Dutch Restrained Eating Scale
What the sources say
- Not checked yetcites Stice, et al., 2004 source
- Not checked yetcites van Strien et al., 1986 source
Strength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“Prospective acquisition correction (PACE) was applied to adjust slice position and orientation, as well as to re-grid residual volume-to-volume motion in real-time during data acquisition for the purpose of reducing motion-induced effects in Study 2 (Thesen et al., 2000).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 2.6 Imaging acquisition, preprocessing and analysis
What the sources say
- Not checked yetcites Thesen et al., 2000 source
Strength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“A cluster level threshold of p < 0.05 corrected for multiple comparisons across the whole brain for each study were derived using Monte Carlo simulations (10,000 iterations) of random noise distribution in the whole brain mask (3×3×3mm) using the 3dClustSim in AFNI (Cox, 1996; Forman et al., 1995).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 2.6 Imaging acquisition, preprocessing and analysis
What the sources say
- Not checked yetcites Cox, 1996 source
- Not checked yetcites Forman et al., 1995 source
Load-bearingStrength:plain· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
Probably not a substantial claim.
In the paper
“In response to pictures of palatable foods, individuals who had successfully recovered from obesity showed greater activation in a region associated with inhibitory control (the superior frontal region) than obese and normal weight individuals, greater activation in a region involved in visual attention (middle temporal region) than normal weight individuals, and less activation in a motor”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 1. Introduction
What the sources say
- Not checked yetcites McCaffery et al., 2009 source
Load-bearingStrength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
Probably not a substantial claim. It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Although this scale correlates with self-reported caloric intake, like all dietary restraint or dieting scales, it does not correlate with objectively measured caloric intake (e.g., Ouwens et al., 2003; Stice, et al., 2004).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 2. Methods > 2.3 Dutch Restrained Eating Scale
What the sources say
- Not checked yetcites Ouwens et al., 2003 source
- Not checked yetcites Stice, et al., 2004 source
Strength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“Experimental research with rats has revealed that acute food deprivation and chronic caloric deprivation results in increased DA release at feeding and increased D2 receptor binding (Thanos et al., 2008)”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Thanos et al., 2008 source
Strength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes? Load-bearing: unclear✓ Based: passes
It may state two separate claims as one.
In the paper
“Interesting, animal experiments show that caloric deprivation selectively increases preferences for high-fat foods (Lucas & Sclafani, 1992).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Lucas & Sclafani, 1992
Strength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“Abstinence from cocaine after a period of regular use resulted in a 17% increase in cells that selectively fire in response to cocaine directed behavior”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Cameron & Carelli, 2012
Strength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“These data collectively suggest that caloric deprivation increases D2R receptor sensitization, which could explain the greater reward value of food after caloric deprivation.”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
Load-bearingStrength:hedged· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✓ Load-bearing: passes✓ Based: passes
It may state two separate claims as one.
- Rests on an assumption: Mechanisms of caloric deprivation observed in rats generalize to humans.
In the paper
“and elevated D2Rs showed enhanced effector striatal coupling (Carr et al., 2003).”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Carr et al., 2003 source
Strength:plain· not yet calibratedCausal:correlational· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“Administration of the D1R agonist SFK-82958 produced enhanced striatal activation”
§ Caloric Deprivation Increases Responsivity of Attention and Reward Brain Regions to Intake, Anticipated Intake, and Images of Palatable Foods > 4. Discussion
What the sources say
- Not checked yetcites Carr et al., 2003 source
Strength:plain· not yet calibratedCausal:direct· not yet calibrated
Tests✓ Asserted: passes✓ Checkable: passes✗ Load-bearing: fails✓ Based: passes
Probably not a substantial claim. The paper’s conclusions may not depend on it.

47 of 47

The paper relies on this without support.
Weight change over the 2-week period is a valid index of negative, neutral, or positive energy balance.
“To assess the impact of longer-term energy balance we used weight change over the 2-week period during which the scan occurred to group participants into three a priori groups”
“This allowed us to contrast the neural response of individuals who were in an objectively measured negative energy balance to those who were in an energy stable or positive energy balance state when the scan took place.”
The paper relies on this without support.
Number of hours since last caloric intake is a valid measure of acute caloric deprivation.
“participants reported the number of hours since their last dietary intake (to the nearest quarter hour)”
“duration of caloric deprivation”
The paper relies on this without support.
BOLD response in attention and reward regions reflects responsivity or reward value to food.
“BOLD response was contrasted during receipt of milkshake versus tasteless solution”
“activation in regions implicated in attention, reward, and motivation”
The paper relies on this without support.
Caloric deprivation weight loss diets typically do not produce lasting weight loss.
“which may explain why caloric deprivation weight loss diets typically do not produce lasting weight loss.”
The paper relies on this without support.
Participants' self-reported duration of elective acute caloric deprivation accurately reflects their actual caloric deprivation.
“participants reporting a longer duration of elective acute caloric deprivation”
“Hours since last caloric intake and negative energy balance status showed no correlation with scores on the Dutch Restrained Eating Scale”
The paper relies on this without support.
Mechanisms of caloric deprivation observed in rats generalize to humans.
“These data collectively suggest that caloric deprivation increases D2R receptor sensitization, which could explain the greater reward value of food after caloric deprivation.”

6 of 6

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

Each contradiction between two passages listed here was confirmed by an independent check.

A negative mean weight change is described as an increase
Minor
The energy-stable group's reported mean change of −0.01 kg is a slight decrease, not an increase.

1 of 1

Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2022) · doi:10.1176/appi.books.9780890425787 · Cited by 23,476
AFNI: Software for analysis and visualization of functional magnetic resonance neuroimages
Cox, R. W. (1996) · Computers and Biomedical Research · doi:10.1006/cbmr.1996.0014 · Cited by 10,913
Neurocircuitry of Addiction
Koob, G. F., & Volkow, N. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.110 · Cited by 5,340
The precuneus: a review of its functional anatomy and behavioural correlates
Cavanna, A. E., & Trimble, M. R. (2006) · Brain · doi:10.1093/brain/awl004 · Cited by 5,128
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
Berridge, K. C., & Robinson, T. E. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00019-8 · Cited by 4,127
Improved assessment of significant activation in functional magnetic resonance imaging (fMRI): use of a cluster-size threshold
Forman, S. D., Cohen, J. D., Fitzgerald, M., Eddy, W. F., Mintun, M. A., & Noll, D. C. (1995) · Magnetic Resonance in Medicine · doi:10.1002/mrm.1910330508 · Cited by 3,202
Dieting and binging: A causal analysis.
Polivy, J., & Herman, C. P. (1985) · American Psychologist · doi:10.1037/0003-066x.40.2.193 · Cited by 1,539
Dieting and binging: A causal analysis.
Polivy, J., & Herman, C. P. (1985) · American Psychologist · doi:10.1037//0003-066x.40.2.193 · Cited by 1,279
A prospective test of the dual pathway model of bulimic pathology: mediating effects of dieting and negative affect
Stice, E. (2001) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.110.1.124 · Cited by 1,251
Self-citation

Flagged first, then by citations

Show all 84 references

Research works printed but not linked: 1

Gautier, 1999, Increased cortical representation of hunger and satiation in obese men, Diabetes, 48, A312

Sorted by citations

Acute social isolation evokes midbrain craving responses similar to hunger
Tomova, L., Wang, K. L., Thompson, T., Matthews, G. A., Takahashi, A., Tye, K. M., & Saxe, R. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-00742-z · Cited by 283
“The targeted effect size was chosen based on findings from studies employing cue-induced craving paradigms for drug craving (53) , food cravings (28, (54) (55) (56) and internet gaming craving (30) which report medium to large effect sizes in cue reactivity (53) .”
Shared and unique mechanisms underlying binge eating disorder and addictive disorders
Schulte, E. M., Grilo, C. M., & Gearhardt, A. N. (2016) · Clinical Psychology Review · doi:10.1016/j.cpr.2016.02.001 · Cited by 271
Increased Prefrontal and Parahippocampal Activation with Reduced Dorsolateral Prefrontal and Insular Cortex Activation to Food Images in Obesity: A Meta-Analysis of fMRI Studies
Brooks, S. J., Cedernaes, J., & Schiöth, H. B. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060393 · Cited by 269
“We observed increased activation in the left dorsomedial prefrontal, right precentral and right parahippocampal gyri in obese subjects, regions linked to attention, motor coordination, and explicit memory, and that are implicated in processes associated with the anticipation of food intake, particularly during perceiv…”
Background
A Review of Interventions that Promote Eating by Internal Cues.
Schaefer, J. T., & Magnuson, A. B. (2014) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2013.12.024 · Cited by 227
“Physiologically, dieting or energy deprivation activates portions of the brain responsible for attention (anterior cingulate cortex) and reward (amygdala) of food.(11) Increasing the reward value of high-energy foods in the brain increases the likelihood of food intake and may result in binge eating.”
Background
Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods
Byrne, C. S., Chambers, E. S., Alhabeeb, H., Chhina, N., Morrison, D. J., Preston, T., Tedford, C., Fitzpatrick, J., Irani, C., Busza, A., et al. (2016) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.126706 · Cited by 201
“Similarly, satiation decreases BOLD responses to food taste in the nucleus accumbens (31), whereas duration of food deprivation correlates with a greater caudate BOLD signal in response to actual and anticipated receipt of palatable food (29).”
Background

See all 162

Authors: Stice, E., Burger, K., & Yokum, S.
Affiliations: Oregon Research Institute (US)
Corresponding author: Stice, Eric
ORCID: Stice, Eric
Burger, Kyle
Yokum, Sonja
Venue: NeuroImage
Publisher: Elsevier BV
Published: 2013-02
Volume: 67
Pages: 322-330
ISSN: 1053-8119 (ISSN-L)
DOI: 10.1016/j.neuroimage.2012.11.028
PMC: PMC3693571
OpenAlex: W2019359264
Semantic Scholar: d625270db3768000736d7210c91ae80a6f829b16
Cited by: 162
References: 84
Citations by year: 2026: 8 · 2025: 8 · 2024: 10 · 2023: 7 · 2022: 9 · 2021: 38 · 2020: 13 · 2019: 6 · 2018: 9 · 2017: 10 · 2016: 13 · 2015: 18 · 2014: 9 · 2013: 4
FWCI: 11.22
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: NeuroImage (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: National Institutes of Health (R1MH64560A, DK080760, DK092468)
Topics: Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
Keywords: caloric deprivation, dietary restraint, binge eating, food reward, negative energy balance, adolescents, anterior cingulate cortex, orbitofrontal cortex, caudate nucleus, hippocampus, motivation, weight loss diet
MeSH terms: Adolescent, Appetite, Attention, Brain Mapping, Cerebral Cortex, Eating, Female, Humans, Male, Reward, Visual Perception, Caloric Restriction, Anticipation, Psychological

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

A language model drew the claims from the paper on 2026-10-09, under version 3 of the claim definition (model deepseek-v4.1-flash, prompt extract-v3).

A second model labelled each claim on 2026-10-09 (model jev-1.13-20260917, definition revision gold-guideline-v0.2).

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Caloric deprivation increases responsivity of attention and reward brain regions to intake, anticipated intake, and images of palatable foods

Abstract

Overview

AI snapshot

TL;DR

Key findings

Methods

Limitations

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks