Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 604

The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.

Memory Engram Cells Have Come of Age

Open access
Tonegawa, Susumu, Liu, Xu, Ramirez, Steve, Redondo, Roger·2015·Neuron
DOI 10.1016/j.neuron.2015.08.002
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.neuron.2015.08.002

Cites

32 of 32 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Research works printed but not linked: 67

  1. Anderson, 2001, Lesions of the human amygdala impair enhanced perception of emotionally salient events, Nature, 411, 305, 10.1038/35077083 · DOI · Paper page
  2. Bailey, 1993, Structural changes accompanying memory storage, Annu. Rev. Physiol., 55, 397, 10.1146/annurev.ph.55.030193.002145 · DOI
  3. Bannerman, 2012, Dissecting spatial knowledge from spatial choice by hippocampal NMDA receptor deletion, Nat. Neurosci., 15, 1153, 10.1038/nn.3166 · DOI
  4. Bliss, 1973, Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path, J. Physiol., 232, 331, 10.1113/jphysiol.1973.sp010273 · DOI · Paper page
  5. Britt, 2012, Synaptic and behavioral profile of multiple glutamatergic inputs to the nucleus accumbens, Neuron, 76, 790, 10.1016/j.neuron.2012.09.040 · DOI · Paper page
  6. Cabeza, 2001, Can medial temporal lobe regions distinguish true from false? An event-related functional MRI study of veridical and illusory recognition memory, Proc. Natl. Acad. Sci. USA, 98, 4805, 10.1073/pnas.081082698 · DOI · Paper page
  7. Chen, 2015, Wireless magnetothermal deep brain stimulation, Science, 347, 1477, 10.1126/science.1261821 · DOI · Paper page
  8. Christian, 2003, Neural substrates of eyeblink conditioning: acquisition and retention, Learn. Mem., 10, 427, 10.1101/lm.59603 · DOI
  9. Cowansage, 2014, Direct reactivation of a coherent neocortical memory of context, Neuron, 84, 432, 10.1016/j.neuron.2014.09.022 · DOI · Paper page
  10. Czajkowski, 2014, Encoding and storage of spatial information in the retrosplenial cortex, Proc. Natl. Acad. Sci. USA, 111, 8661, 10.1073/pnas.1313222111 · DOI
  11. Daoudal, 2003, Long-term plasticity of intrinsic excitability: learning rules and mechanisms, Learn. Mem., 10, 456, 10.1101/lm.64103 · DOI · Paper page
  12. Deng, 2013, Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice, eLife, 2, e00312, 10.7554/eLife.00312 · DOI
  13. Denny, 2014, Hippocampal memory traces are differentially modulated by experience, time, and adult neurogenesis, Neuron, 83, 189, 10.1016/j.neuron.2014.05.018 · DOI · Paper page
  14. Do-Monte, 2015, A temporal shift in the circuits mediating retrieval of fear memory, Nature, 519, 460, 10.1038/nature14030 · DOI · Paper page
  15. Eguchi, 2009, In vivo and in vitro visualization of gene expression dynamics over extensive areas of the brain, Neuroimage, 44, 1274, 10.1016/j.neuroimage.2008.10.046 · DOI
  16. Ehrlich, 2009, Amygdala inhibitory circuits and the control of fear memory, Neuron, 62, 757, 10.1016/j.neuron.2009.05.026 · DOI · Paper page
  17. Flavell, 2008, Signaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous system, Annu. Rev. Neurosci., 31, 563, 10.1146/annurev.neuro.31.060407.125631 · DOI · Paper page
  18. Fuster, 1981, Inferotemporal neurons distinguish and retain behaviorally relevant features of visual stimuli, Science, 212, 952, 10.1126/science.7233192 · DOI · Paper page
  19. Gelbard-Sagiv, 2008, Internally generated reactivation of single neurons in human hippocampus during free recall, Science, 322, 96, 10.1126/science.1164685 · DOI · Paper page
  20. Gerber, 2004, An engram found? Evaluating the evidence from fruit flies, Curr. Opin. Neurobiol., 14, 737, 10.1016/j.conb.2004.10.014 · DOI
  21. Gore, 2015, Neural Representations of Unconditioned Stimuli in Basolateral Amygdala Mediate Innate and Learned Responses, Cell, 162, 134, 10.1016/j.cell.2015.06.027 · DOI
  22. Goshen, 2011, Dynamics of retrieval strategies for remote memories, Cell, 147, 678, 10.1016/j.cell.2011.09.033 · DOI · Paper page
  23. Han, 2007, Neuronal competition and selection during memory formation, Science, 316, 457, 10.1126/science.1139438 · DOI · Paper page
  24. Han, 2009, Selective erasure of a fear memory, Science, 323, 1492, 10.1126/science.1164139 · DOI · Paper page
  25. Holtmaat, 2006, Experience-dependent and cell-type-specific spine growth in the neocortex, Nature, 441, 979, 10.1038/nature04783 · DOI · Paper page
  26. Horn, 2004, Pathways of the past: the imprint of memory, Nat. Rev. Neurosci., 5, 108, 10.1038/nrn1324 · DOI · Paper page
  27. Hsiang, 2014, Manipulating a “cocaine engram” in mice, J. Neurosci., 34, 14115, 10.1523/JNEUROSCI.3327-14.2014 · DOI · Paper page
  28. Ji, 2008, Differential roles for hippocampal areas CA1 and CA3 in the contextual encoding and retrieval of extinguished fear, Learn. Mem., 15, 244, 10.1101/lm.794808 · DOI
  29. Kass, 2013, Fear learning enhances neural responses to threat-predictive sensory stimuli, Science, 342, 1389, 10.1126/science.1244916 · DOI
  30. Kim, 2013, Injectable, cellular-scale optoelectronics with applications for wireless optogenetics, Science, 340, 211, 10.1126/science.1232437 · DOI · Paper page
  31. Kim, 2014, Memory recall and modifications by activating neurons with elevated CREB, Nat. Neurosci., 17, 65, 10.1038/nn.3592 · DOI
  32. Koya, 2009, Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization, Nat. Neurosci., 12, 1069, 10.1038/nn.2364 · DOI · Paper page
  33. Lashley, 1950, In search of the engram, Symp. Soc. Exp. Biol., 4, 454
  34. Lee, 2004, Differential contributions of dorsal hippocampal subregions to memory acquisition and retrieval in contextual fear-conditioning, Hippocampus, 14, 301, 10.1002/hipo.10177 · DOI · Paper page
  35. Leutgeb, 2004, Distinct ensemble codes in hippocampal areas CA3 and CA1, Science, 305, 1295, 10.1126/science.1100265 · DOI
  36. Liu, 2012, Optogenetic stimulation of a hippocampal engram activates fear memory recall, Nature, 484, 381, 10.1038/nature11028 · DOI
  37. Loftus, 2003, Our changeable memories: legal and practical implications, Nat. Rev. Neurosci., 4, 231, 10.1038/nrn1054 · DOI
  38. Marr, 1970, A theory for cerebral neocortex, Proc. R. Soc. Lond. B Biol. Sci., 176, 161, 10.1098/rspb.1970.0040 · DOI
  39. Martin, 2002, New life in an old idea: the synaptic plasticity and memory hypothesis revisited, Hippocampus, 12, 609, 10.1002/hipo.10107 · DOI · Paper page
  40. Matsuo, 2015, Irreplaceability of neuronal ensembles after memory allocation, Cell Rep., 11, 351, 10.1016/j.celrep.2015.03.042 · DOI
  41. Matsuo, 2008, Spine-type-specific recruitment of newly synthesized AMPA receptors with learning, Science, 319, 1104, 10.1126/science.1149967 · DOI · Paper page
  42. McTighe, 2010, Paradoxical false memory for objects after brain damage, Science, 330, 1408, 10.1126/science.1194780 · DOI
  43. Miyashita, 1988, Neuronal correlate of visual associative long-term memory in the primate temporal cortex, Nature, 335, 817, 10.1038/335817a0 · DOI · Paper page
  44. Nabavi, 2014, Engineering a memory with LTD and LTP, Nature, 511, 348, 10.1038/nature13294 · DOI · Paper page
  45. Nakazawa, 2003, Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience, Neuron, 38, 305, 10.1016/S0896-6273(03)00165-X · DOI
  46. Nieh, 2013, Optogenetic dissection of neural circuits underlying emotional valence and motivated behaviors, Brain Res., 1511, 73, 10.1016/j.brainres.2012.11.001 · DOI
  47. Nonaka, 2014, Synaptic plasticity associated with a memory engram in the basolateral amygdala, J. Neurosci., 34, 9305, 10.1523/JNEUROSCI.4233-13.2014 · DOI
  48. Ohkawa, 2015, Artificial association of pre-stored information to generate a qualitatively new memory, Cell Rep., 11, 261, 10.1016/j.celrep.2015.03.017 · DOI
  49. Olds, 1972, Learning centers of rat brain mapped by measuring latencies of conditioned unit responses, J. Neurophysiol., 35, 202, 10.1152/jn.1972.35.2.202 · DOI · Paper page
  50. Ramirez, 2015, Activating positive memory engrams suppresses depression-like behaviour, Nature, 522, 335, 10.1038/nature14514 · DOI
  51. Reijmers, 2007, Localization of a stable neural correlate of associative memory, Science, 317, 1230, 10.1126/science.1143839 · DOI
  52. Roediger, 1995, Creating false memories: Remembering words not presented in lists, J. Exp. Psychol. Learn. Mem. Cogn., 21, 803, 10.1037/0278-7393.21.4.803 · DOI · Paper page
  53. Romberg, 2012, False recognition in a mouse model of Alzheimer’s disease: rescue with sensory restriction and memantine, Brain, 135, 2103, 10.1093/brain/aws074 · DOI
  54. Ryan, 2015, Memory. Engram cells retain memory under retrograde amnesia, Science, 348, 1007, 10.1126/science.aaa5542 · DOI · Paper page
  55. Schacter, 1978, Richard Semon’ s Theory of Memory, J. Verbal Learn. Verbal Behav., 17, 721, 10.1016/S0022-5371(78)90443-7 · DOI
  56. Scoville, 1957, Loss of recent memory after bilateral hippocampal lesions, J. Neurol. Neurosurg. Psychiatry, 20, 11, 10.1136/jnnp.20.1.11 · DOI · Paper page
  57. Squire, 2004, Memory systems of the brain: a brief history and current perspective, Neurobiol. Learn. Mem., 82, 171, 10.1016/j.nlm.2004.06.005 · DOI · Paper page
  58. Tanaka, 2014, Cortical representations are reinstated by the hippocampus during memory retrieval, Neuron, 84, 347, 10.1016/j.neuron.2014.09.037 · DOI
  59. Tayler, 2013, Reactivation of neural ensembles during the retrieval of recent and remote memory, Curr. Biol., 23, 99, 10.1016/j.cub.2012.11.019 · DOI · Paper page
  60. Tonegawa, 2015, Memory engram storage and retrieval, Current Opinion in Neuroscience, 35, 101, 10.1016/j.conb.2015.07.009 · DOI · Paper page
  61. Trouche, 2013, Fear extinction causes target-specific remodeling of perisomatic inhibitory synapses, Neuron, 80, 1054, 10.1016/j.neuron.2013.07.047 · DOI
  62. Weinberger, 2004, Specific long-term memory traces in primary auditory cortex, Nat. Rev. Neurosci., 5, 279, 10.1038/nrn1366 · DOI · Paper page
  63. Xie, 2014, In vivo imaging of immediate early gene expression reveals layer-specific memory traces in the mammalian brain, Proc. Natl. Acad. Sci. USA, 111, 2788, 10.1073/pnas.1316808111 · DOI
  64. Yiu, 2014, Neurons are recruited to a memory trace based on relative neuronal excitability immediately before training, Neuron, 83, 722, 10.1016/j.neuron.2014.07.017 · DOI · Paper page
  65. Yu, 2006, Drosophila α/β mushroom body neurons form a branch-specific, long-term cellular memory trace after spaced olfactory conditioning, Neuron, 52, 845, 10.1016/j.neuron.2006.10.030 · DOI · Paper page
  66. Zelikowsky, 2014, Neuronal ensembles in amygdala, hippocampus, and prefrontal cortex track differential components of contextual fear, J. Neurosci., 34, 8462, 10.1523/JNEUROSCI.3624-13.2014 · DOI
  67. Zhou, 2009, CREB regulates excitability and the allocation of memory to subsets of neurons in the amygdala, Nat. Neurosci., 12, 1438, 10.1038/nn.2405 · DOI

Cited by

See all 604

Metadata

Authors
Tonegawa, S., Liu, X., Ramirez, S., & Redondo, R.
Venue
Neuron
Publisher
Elsevier BV
Published
2015-09
Volume
87
Issue
5
Pages
918-931
ISSN
0896-6273 (ISSN-L)
DOI
10.1016/j.neuron.2015.08.002
OpenAlex
W1920095995
Cited by
604
References
32
FWCI
25.08
Type
journal article
Language
en
Open access
bronze
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.