Cited by 69Reproductive System and PregnancyMicroRNA in disease regulationEndometriosis Research and Treatment

Tissue and circulating microRNA influence reproductive function in endometrial disease

Louise Hull, M., Nisenblat, Victoria·2013·Reproductive BioMedicine Online

Abstract

microRNA (miRNA) have emerged as important epigenetic modulators of gene expression in diverse pathological and physiological processes. In the endometrium, miRNA appear to have a role in the dynamic changes associated with the menstrual cycle, in implantation and in the pathophysiology associated with reproductive disorders such as recurrent miscarriage and endometriosis. This review explores the role of miRNA in endometrial physiology and endometrial disorders of reproduction and also raises the prospect that circulating miRNA may modulate endometrial function or reflect disordered endometrial activity. The clinical potential to use miRNA in diagnostic tests of endometrial function or in the treatment of endometrial disorders will also be discussed.

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Crossref · 10.1016/j.rbmo.2013.07.012

Cites

115 of 115 references verified0 citation errors · 0 not checkable

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  • Results of studies with heterogeneous designs apply only to the cohort of patients and control subjects selected for that study.

    “As cautioned by Hull and Nisenblat, and echoed by the conclusions from Cochrane Database of Systematic Reviews, the interpretation of data can not be hindered by the heterogeneity of study designs, where the results apply only to the cohort of patients and control subjects selected for that study (87).”

    From Biomarkers in endometriosis: Challenges and opportunities (2017) · cites this paper as [87]

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Authors
Louise Hull, M., & Nisenblat, V.
Affiliations
Women's and Children's Hospital (AU)
Venue
Reproductive BioMedicine Online
Publisher
Elsevier BV
Published
2013-11
Volume
27
Issue
5
Pages
515-529
ISSN
1472-6483 (ISSN-L)
OpenAlex
W2033570297
Cited by
69
References
114
Citations by year
2024: 4 · 2023: 5 · 2022: 4 · 2021: 7 · 2020: 6 · 2019: 8 · 2018: 5 · 2017: 7 · 2016: 7 · 2015: 10 · 2014: 3 · 2013: 3
FWCI
0.67
Type
journal article
Language
en
Open access
closed
Locations
  • Reproductive BioMedicine Online (publishedVersion)
  • PubMed (publishedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
Topics
  • Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › MicroRNA in disease regulation
  • Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
Keywords
microRNA, endometrium, endometrial disease, recurrent pregnancy loss, endometriosis, implantation, circulating microRNAs, epigenetic regulation, menstrual cycle, endometrial function, biomarkers
MeSH terms
Abortion, Habitual, Endometriosis, Endometrium, Female, Fertility, Humans, Menstrual Cycle, Models, Biological, Embryo Implantation, Uterine Diseases, Biomarkers, MicroRNAs, Epigenesis, Genetic

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