Intronic microRNA precursors that bypass Drosha processing
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For the majority of miRNAs, both strands have precisely defined 5' termini compared to their 3' ends, suggesting evolutionary pressure to maintain the target-determining sequence of both strands.
“In addition, for majority of miRNAs, both strands have precisely defined 5′ termini, compared to their 3′ ends, suggesting evolutionary pressure to maintain the target‐determining sequence of both strands (Okamura et al., 2008; Ruby, Jan, et al., 2007; Ruby, Stark, et al., 2007; Seitz, Ghildiyal, & Zamore, 2008).”
From microRNA strand selection: Unwinding the rules (2021) · cites this paper as Ruby, Jan, et al., 2007
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“85 The mirtrons are included in the 5 ′ UTR sequence to be processed by splicing pre-mRNA like short introns (see Fig.”
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- Authors
- Ruby, J. G., Jan, C. H., & Bartel, D. P.
- Venue
- Nature
- Published
- 2007-06-24
- Volume
- 448
- Issue
- 7149
- Pages
- 83-86
- ISSN
- 0028-0836
- 1476-4687
- Cited by
- 1,445
- References
- 0
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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