Cited by 218Inflammatory Bowel DiseaseGastrointestinal motility and disordersPsychosomatic Disorders and Their Treatments

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Quality of life in inflammatory bowel disease in remission: the impact of IBS-like symptoms and associated psychological factors

SimrÃ©n, M·2002·The American Journal of Gastroenterology

DOI 10.1016/s0002-9270(01)04037-0

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Abstract

OBJECTIVES: Quality of life is reduced in inflammatory bowel disease (IBD). Whether or not this is true in IBD patients in long-standing remission is unclear. Symptoms compatible with irritable bowel syndrome (IBS) are common in IBD patients in remission. The importance of psychological factors in this process is a matter of controversy. METHODS: Forty-three patients with ulcerative colitis (UC) and 40 with Crohn’s disease (CD), who had been in remission for at least 1 yr according to laboratory parameters and clinical and endoscopical appearance, were included. These patients completed four different self-administered questionnaires, evaluating GI symptoms, anxiety, depression, and psychological general well-being. The two patient groups were compared with the general population, and within-group comparisons in psychometric scores were made between patients with and without IBS-like symptoms. RESULTS: The psychological well-being in IBD patients in long-standing remission was similar to that of the general population, despite the presence of more severe GI symptoms. CD patients reported more psychosocial dysfunction, reduced well-being, and GI symptoms than UC patients. Thirty-three percent of UC patients and 57% of CD patients had IBS-like symptoms. The group with IBS-like symptoms (both UC and CD) had higher levels of anxiety and depression and more reduced well-being than those without. Anxiety and reduced vitality were found to be independent predictors for IBS-like symptoms in these patients. CONCLUSION: The prevalence of IBS-like symptoms in IBD patients in long-standing remission is two to three times higher than that in the normal population. Psychological factors seem to be of importance in this process. However, as a group IBD patients in remission demonstrate psychological well-being comparable to that of the general population.

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Venue: The American Journal of Gastroenterology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2002-02
Volume: 97
Issue: 2
Pages: 389-396
ISSN: 0002-9270 (ISSN-L)
DOI: 10.1016/s0002-9270(01)04037-0
OpenAlex: W4231548066
Cited by: 186
References: 0
Citations by year: 2026: 2 · 2025: 8 · 2024: 3 · 2023: 12 · 2022: 13 · 2021: 10 · 2020: 11 · 2019: 19 · 2018: 12 · 2017: 7 · 2016: 5 · 2015: 4 · 2014: 4 · 2013: 4 · 2012: 14
FWCI: 1.59
Type: journal article
Language: en
Open access: closed
Locations: The American Journal of Gastroenterology (publishedVersion)
Funders: Vetenskapsrådet
Topics: Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords: inflammatory bowel disease, quality of life, IBS-like symptoms, ulcerative colitis, Crohn's disease, remission, anxiety, depression, psychological well-being, gastrointestinal symptoms, vitality, psychosocial dysfunction

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Quality of life in inflammatory bowel disease in remission: the impact of IBS-like symptoms and associated psychological factors

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