Cerebrospinal fluid amines and higher-lethality suicide attempts in depressed inpatients
Open accessAbstract
Previous studies have found that not all suicide attempters with major depression have reduced serotonergic activity based on low cerebrospinal fluid 5-hydroxyindoleacetic acid (CSF- 5-HIAA) levels. In this study we hypothesized that serotonergic function is lower in depressed patients who have carried out high-lethality suicide attempts resulting in more medical damage, which might explain differences in serotonergic activity among depressed suicide attempters. We assessed the relationship of CSF 5-HIAA and other amine metabolites to the most lethal lifetime suicide attempt in 22 drug-free inpatients with major depression. CSF 5-HIAA levels were lower in depressed patients with a history of a high-lethality or well-planned suicide attempt compared to depressed patients with a history of only low-lethality suicide attempt(s). Other CSF monoamine metabolites did not correlate with suicidal behavior. Low serotonergic activity may correlate with a predisposition to more lethal suicide attempts in major depression.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Serotonergic release deficits in the ventral PFC and ACC are more prominent in high-lethality suicidal behavior and suicide death.
“4) serotonergic release deficits in the ventral PFC and ACC that are more prominent in high-lethality suicidal behavior and suicide death;”
From A brain-centric model of suicidal behavior (2020) · cites this paper as [117]
Serotonin dysfunction is more prominent in higher-lethality suicidal behavior, indicating localized PFC hypofunction.
“Serotonin dysfunction is more prominent in higher-lethality suicidal behavior (117), indicating localized PFC hypofunction (118).”
From A brain-centric model of suicidal behavior (2020) · cites this paper as [117]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817 · see citing works
The Structured Clinical Interview for DSM-III-R (SCID): I: History, Rationale, and Description
Spitzer, R. L. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820080032005 · Cited by 4,336 · see citing works
Assessment of suicidal intention: The Scale for Suicide Ideation.
Beck, A. T., Kovacs, M., & Weissman, A. (1979) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.47.2.343 · Cited by 3,419 · see citing works
5-HIAA in the Cerebrospinal Fluid
Åsberg, M. (1976) · Archives of General Psychiatry · doi:10.1001/archpsyc.1976.01770100055005 · Cited by 1,448 · see citing works
Linnoila, M., Virkkunen, M., Scheinin, M., Nuutila, A., Rimon, R., & Goodwin, F. K. (1983) · Life Sciences · doi:10.1016/0024-3205(83)90344-2 · Cited by 1,308 · see citing works
Aggression in humans correlates with cerebrospinal fluid amine metabolites
Brown, G. L., Goodwin, F. K., Ballenger, J. C., Goyer, P. F., & Major, L. F. (1979) · Psychiatry Research · doi:10.1016/0165-1781(79)90053-2 · Cited by 1,133 · see citing works
Aggression, suicide, and serotonin: relationships to CSF amine metabolites
Brown, G. L., Ebert, M. H., Goyer, P. F., Jimerson, D. C., Klein, W. J., Bunney, W. E., & Goodwin, F. K. (1982) · American Journal of Psychiatry · doi:10.1176/ajp.139.6.741 · Cited by 907 · see citing works
Monoamine Metabolites in CSF and Suicidal Behavior
Träskman, L. (1981) · Archives of General Psychiatry · doi:10.1001/archpsyc.1981.01780310031002 · Cited by 689 · see citing works
(1956) · BMJ · doi:10.1136/bmj.2.4996.813 · Cited by 640 · see citing works
INCREASED SEROTONIN-2 BINDING SITES IN FRONTAL CORTEX OF SUICIDE VICTIMS
Stanley, M., & Mann, J. J. (1983) · The Lancet · doi:10.1016/s0140-6736(83)92590-4 · Cited by 527 · see citing works
NEUROBIOLOGY OF MOOD DISORDERS
(2017) · International Supply Chain Technology Journal · doi:10.20545/isctj.v03.n12.03 · Cited by 477 · see citing works
Tritiated Imipramine Binding Sites Are Decreased in the Frontal Cortex of Suicides
Stanley, M., Virgilio, J., & Gershon, S. (1982) · Science · doi:10.1126/science.7079769 · Cited by 473 · see citing works
Classification of suicidal behaviors: I. Quantifying intent and medical lethality
(1975) · American Journal of Psychiatry · doi:10.1176/ajp.132.3.285 · Cited by 460 · see citing works
Neurobiology of Mood Disorders
Sullivan, J. L. (1985) · Psychosomatics · doi:10.1016/s0033-3182(85)72842-3 · Cited by 450 · see citing works
5-Hydroxytryptamine in the Hind-Brain of Depressive Suicides
Shaw, D. M., Camps, F. E., & Eccleston, E. (1967) · The British Journal of Psychiatry · doi:10.1192/bjp.113.505.1407 · Cited by 431 · see citing works
Arango, V. (1990) · Archives of General Psychiatry · doi:10.1001/archpsyc.1990.01810230054009 · Cited by 420 · see citing works
Cerebrospinal Fluid Monoamine Metabolite Levels in Male Arsonists
Virkkunen, M. (1987) · Archives of General Psychiatry · doi:10.1001/archpsyc.1987.01800150053007 · Cited by 394 · see citing works
The Personality Disorder Examination: A Preliminary Report
Loranger, A. W., Susman, V. L., Oldham, J. M., & Russakoff, L. M. (1987) · Journal of Personality Disorders · doi:10.1521/pedi.1987.1.1.1 · Cited by 311 · see citing works
Bourne, H. R. (1968) · The Lancet · doi:10.1016/s0140-6736(68)92459-8 · Cited by 304 · see citing works
Cerebrospinal Fluid Monoamine Metabolites and Suicidal Behavior in Depressed Patients
Roy, A. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810070035005 · Cited by 284 · see citing works
Mann, J. J. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820060022003 · Cited by 281 · see citing works
Homicide, suicide and CSF 5‐HIAA
Lidberg, L., Tuck, J. R., Åsberg, M., Scalia‐Tomba, G., & Bertilsson, L. (1985) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1985.tb01279.x · Cited by 270 · see citing works
Pare, C. M. B., Yeung, D. P. H., Price, K. S., & Stacey, R. S. (1969) · The Lancet · doi:10.1016/s0140-6736(69)92442-8 · Cited by 262 · see citing works
CSF 5‐HIAA Predicts Suicide Risk After Attempted Suicide
Nordström, P., Samuelsson, M., Åsberg, M., Träskman‐Bendz, L., Åberg‐Wistedt, A., Nordin, C., & Bertilsson, L. (1994) · Suicide and Life-Threatening Behavior · doi:10.1111/j.1943-278x.1994.tb00657.x · Cited by 257 · see citing works
Trait-State Artifacts and the Diagnosis of Personality Disorders
Loranger, A. W. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810320044007 · Cited by 251 · see citing works
Clinical predictors of eventual suicide: a 5- to 10-year prospective study of suicide attempters
Beck, A. T., & Steer, R. A. (1989) · Journal of Affective Disorders · doi:10.1016/0165-0327(89)90001-3 · Cited by 251 · see citing works
Higley, J. D. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820200025003 · Cited by 250 · see citing works
Correlations between aminergic metabolites simultaneously obtained from human CSF and brain
Stanley, M., Träskman‐Bendz, L., & Dorovini-Zis, K. (1985) · Life Sciences · doi:10.1016/0024-3205(85)90242-5 · Cited by 247 · see citing works
Scheinin, M., Chang, W., Kirk, K. L., & Linnoila, M. (1983) · Analytical Biochemistry · doi:10.1016/0003-2697(83)90162-8 · Cited by 244 · see citing works
Beskow, J., Gottfries, C. G., Roos, B. E., & Winblad, B. G. (1976) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1976.tb00054.x · Cited by 225 · see citing works
Depression, suicide and the metabolism of serotonin in the brain
van Praag, H. M. (1982) · Journal of Affective Disorders · doi:10.1016/0165-0327(82)90025-8 · Cited by 215 · see citing works
Lloyd, K. G., Farley, I. J., Jh, D., & Hornykiewicz, O. (1974) · PubMed · Cited by 210 · see citing works
Roy, A., Agren, H., Pickar, D., Linnoila, M., Doran, A. R., Cutler, N. R., & Paul, S. M. (1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.12.1539 · Cited by 191 · see citing works
Evidence for the 5-HT Hypothesis of Suicide A Review of Post-mortem Studies
Mann, J. J., Arango, V., Marzuk, P. M., Theccanat, S. M., & Reis, D. J. (1989) · The British Journal of Psychiatry · doi:10.1192/s000712500029171x · Cited by 183 · see citing works
Attempted Suicide Characteristics and Cerebrospinal Fluid Amine Metabolites in Depressed Inpatients
Mann, J. (1996) · Neuropsychopharmacology · doi:10.1016/s0893-133x(96)00102-9 · Cited by 178 · see citing works
Self-citationArmitage, R., Trivedi, M. H., Hoffmann, R. F., & Rush, A. J. (1997) · Depression and Anxiety · doi:10.1002/(sici)1520-6394(1997)5:2 · Cited by 169 · see citing works
Prolactin Response to Fenfluramine and Suicide Attempt Lethality in Major Depression
Malone, K. M., Corbitt, E. M., Li, S., & Mann, J. J. (1996) · The British Journal of Psychiatry · doi:10.1192/bjp.168.3.324 · Cited by 157 · see citing works
Self-citationSuicide and attempted suicide.
Brooke, E. M. (1974) · PsycEXTRA Dataset · doi:10.1037/e445562004-001 · Cited by 147 · see citing works
Serotonin and 5-Hydroxyindoleacetic Acid in Brains of Suicide Victims
Korpi, E. R. (1986) · Archives of General Psychiatry · doi:10.1001/archpsyc.1986.01800060088011 · Cited by 123 · see citing works
Amine metabolites and neuroendocrine responses related to depression and suicide
Bánki, C. M., & Arató, M. (1983) · Journal of Affective Disorders · doi:10.1016/0165-0327(83)90045-9 · Cited by 123 · see citing works
Integration of Neurobiology and Psychopathology in a Unified Model of Suicidal Behavior
Mann, J. J., & Arango, V. (1992) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199204001-00001 · Cited by 118 · see citing works
Cooper, S. J., King, D. J., & Kelly, C. B. (1992) · The Lancet · doi:10.1016/0140-6736(92)92819-2 · Cited by 110 · see citing works
Biogenic amine metabolites in cerebrospinal fluid of patients with affective disorders
Vestergaard, P., Sørensen, T., Hoppe, E., Rafaelsen, O. J., Yates, C. M., & Nicolaou, N. (1978) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1978.tb06924.x · Cited by 100 · see citing works
The Emergence of Suicidal Ideation and Behavior During Antidepressant Pharmacotherapy
Mann, J. J. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810350067011 · Cited by 100 · see citing works
Cochran, E., Robins, E., & Grote, S. S. (1976) · PubMed · Cited by 99 · see citing works
López-Ibor, J. J., Sáiz-Ruiz, J., & Cobos, J. P. D. L. (2008) · Neuropsychobiology · doi:10.1159/000118207 · Cited by 96 · see citing works
Factor Composition of the Suicide Intent Scale
Mieczkowski, T. A., Sweeney, J. A., Haas, G. L., Junker, B. W., Brown, R. P., & Mann, J. J. (1993) · Suicide and Life-Threatening Behavior · doi:10.1111/j.1943-278x.1993.tb00277.x · Cited by 89 · see citing works
Biochemistry and suicidal behavior in depressed patients
Secunda, S. K., Cross, C. K., Koslow, S. H., Katz, M. M., Kocsis, J. H., Maas, J. W., & LANDIS, H. D. (1986) · Biological Psychiatry · doi:10.1016/0006-3223(86)90241-6 · Cited by 81 · see citing works
Skin Conductance Habituation and Cerebrospinal Fluid 5-Hydroxyindoleacetic Acid in Suicidal Patients
Edman, G. (1986) · Archives of General Psychiatry · doi:10.1001/archpsyc.1986.01800060080010 · Cited by 80 · see citing works
CSF 5-HIAA and HVA concentrations in elderly depressed patients who attempted suicide
Jones, J. S., Stanley, B., Mann, J. J., FRANCES, A. J., Guido, J. R., Träskman‐Bendz, L., Winchel, R., Brown, R. P., & Stanley, M. (1990) · American Journal of Psychiatry · doi:10.1176/ajp.147.9.1225 · Cited by 78 · see citing works
CSF 5HIAA and personal and family history of suicide in affectively III patients: A negative study
Roy‐Byrne, P., Post, R. M., Rubinow, D. R., Linnoila, M., Savard, R. J., & Davis, D. A. (1983) · Psychiatry Research · doi:10.1016/0165-1781(83)90073-2 · Cited by 72 · see citing works
Editor's Preface: Antidepressants of the Future
Priest, R. G. (1989) · The British Journal of Psychiatry · doi:10.1192/s0007125000297420 · Cited by 70 · see citing works
Studies of CSF 5-HIAA in Depression and Suicidal Behaviour
Åsberg, M., & Träskman, L. (1981) · Advances in experimental medicine and biology · doi:10.1007/978-1-4684-3860-4_41 · Cited by 67 · see citing works
Biology of schizophrenia and affective disease
Watson, S. J., & Meeting, M. D. (1996) · American Psychiatric Press eBooks · Cited by 53 · see citing works
Sg, M., & Robins, E. (1975) · PubMed · Cited by 49 · see citing works
Westenberg, H. G. M., & Verhoeven, W. M. A. (1988) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1988.tb06382.x · Cited by 37 · see citing works
Relevance of serotonergic postmortem studies to suicidal behavior
Arango, V., & Mann, J. J. (1992) · International Review of Psychiatry · doi:10.3109/09540269209066310 · Cited by 34 · see citing works
Suicidal ideation and biogenic amines in depression.
Palaniappan, V., Ramachandran, & Somasundaram, O. (1983) · PubMed · Cited by 34 · see citing works
Reproducibility of monoamine metabolite measurements in human cerebrospinal fluid
Hildebrand, J. G., Bourgeois, F., Buyse, M. E., Przedborski, S., & Goldman, S. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1990.tb00989.x · Cited by 30 · see citing works
Lennard-Jones, J. E., & Asher, R. (1959) · The Lancet · doi:10.1016/s0140-6736(59)90723-8 · Cited by 22 · see citing works
Suicidal potential in depression: focus on CSF monoamine and purine metabolites.
Ågren, H., & Niklasson, F. (1986) · PubMed · Cited by 22 · see citing works
Suicidal Behavior and Psychotropic Medication
Accepted as a Consensus Statement by the ACNP Council, M. 2. (1993) · Neuropsychopharmacology · doi:10.1038/npp.1993.79 · Cited by 22 · see citing works
Nordin, C. (1988) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1988.tb06411.x · Cited by 16 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- J.J. Mann and K.M. Malone 1997;41:162-171
Cited by
Sorted by citations
Nock, M. K., Borges, G., Bromet, E. J., Cha, C. B., Kessler, R. C., & Lee, S. (2008) · Epidemiologic Reviews · doi:10.1093/epirev/mxn002 · Cited by 2,897 · see citing works
Toward a clinical model of suicidal behavior in psychiatric patients
Mann, J. J., Waternaux, C., Haas, G. L., & Malone, K. M. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.2.181 · Cited by 1,791 · see citing works
Self-citationNeurobiology of suicidal behaviour
Mann, J. J. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1220 · Cited by 1,260 · see citing works
Self-citationThe role of dopamine in the pathophysiology of depression
Dunlop, B. W., & Nemeroff, C. B. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.3.327 · Cited by 1,244 · see citing works
Seo, D., Patrick, C. J., & Kennealy, P. J. (2008) · Aggression and Violent Behavior · doi:10.1016/j.avb.2008.06.003 · Cited by 520 · see citing works
Brodsky, B. S., Oquendo, M., Ellis, S. P., Haas, G. L., Malone, K. M., & Mann, J. J. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.11.1871 · Cited by 438 · see citing works
Self-citationAggression, Impulsivity, and Suicide Behavior: A Review of the Literature
Gvion, Y., & Apter, A. (2011) · Archives of Suicide Research · doi:10.1080/13811118.2011.565265 · Cited by 426 · see citing works
Neuropsychological dysfunction in depressed suicide attempters
Keilp, J. G., Sackeim, H. A., Brodsky, B. S., Oquendo, M. A., Malone, K. M., & Mann, J. J. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.5.735 · Cited by 372 · see citing works
Self-citationArango, V (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(01)00310-4 · Cited by 368 · see citing works
Persistent pain and depression: A biopsychosocial perspective
Campbell, L. C., Clauw, D. J., & Keefe, F. J. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00545-6 · Cited by 362 · see citing works
Omega-3 fatty acids and depression: scientific evidence and biological mechanisms
Grosso, G., Galvano, F., Marventano, S., Malaguarnera, M., Bucolo, C., Drago, F., & Caraci, F. (2014) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2014/313570 · Cited by 351 · see citing works
Oquendo, M. A., Placidi, G. P. A., Malone, K. M., Campbell, C., Keilp, J., Brodsky, B., Kegeles, L. S., Cooper, T. B., Parsey, R. V., Van Heertum, R. L., et al. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.1.14 · Cited by 313 · see citing works
Self-citationReconsidering the link between impulsivity and suicidal behavior
Anestis, M. D., Soberay, K. A., Gutierrez, P. M., Hernández, T. D., & Joiner, T. E. (2014) · Personality and Social Psychology Review · doi:10.1177/1088868314535988 · Cited by 307 · see citing works
Characteristics of Borderline Personality Disorder Associated With Suicidal Behavior
Brodsky, B. S., Malone, K. M., Ellis, S. P., Dulit, R. A., & Mann, J. J. (1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.12.1715 · Cited by 297 · see citing works
Self-citationA brain-centric model of suicidal behavior
Mann, J. J., & Rizk, M. M. (2020) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20081224 · Cited by 214 · see citing works
More tryptophan hydroxylase in the brainstem dorsal raphe nucleus in depressed suicides
Boldrini, M., Underwood, M. D., Mann, J. J., & Arango, V. (2005) · Brain Research · doi:10.1016/j.brainres.2005.01.083 · Cited by 174 · see citing works
Smoking and the Risk of Suicidal Behavior: A Prospective Study of a Community Sample
Breslau, N., Schultz, L. R., Johnson, E. O., Peterson, E. L., & Davis, G. C. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.3.328 · Cited by 175 · see citing works
Bach-Mizrachi, H., Underwood, M. D., Tin, A., Ellis, S. P., Mann, J. J., & Arango, V (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002143 · Cited by 153 · see citing works
Reduced cerebrospinal HVA concentrations and HVA/5-HIAA ratios in suicide attempters
Engström, G., Alling, C., Blennow, K., Regnéll, G., & Träskman-Bendz, L. (1999) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(99)00016-4 · Cited by 157 · see citing works
Lauterbach, E., Felber, W., Müller‐Oerlinghausen, B., Ahrens, B., Bronisch, T., Meyer, T., Kilb, B., Lewitzka, U., Hawellek, B., Quante, A., et al. (2008) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2008.01266.x · Cited by 154 · see citing works
Serotonergic genes and suicide: A systematic review
Antypa, N., Serretti, A., & Rujescu, D. (2013) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2013.03.013 · Cited by 150 · see citing works
Behind impulsive suicide attempts: Indications from a community study
Wyder, M., & De Leo, D. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.02.015 · Cited by 132 · see citing works
Underwood, M. D., Kassir, S. A., Bakalian, M. J., Galfalvy, H., Dwork, A. J., Mann, J. J., & Arango, V. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0309-1 · Cited by 128 · see citing works
Mental pain and its communication in medically serious suicide attempts: an “impossible situation”
Levi, Y., Horesh, N., Fischel, T., Treves, I., Or, E., & Apter, A. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.02.022 · Cited by 125 · see citing works
Toward fine-grained phenotyping of suicidal behavior: the role of suicidal subtypes
Bernanke, J. A., Stanley, B. H., & Oquendo, M. A. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.123 · Cited by 122 · see citing works
Suicide and Alzheimer’s pathology in the elderly: a case–control study
Rubio, A., Vestner, A. L., Stewart, J. M., Forbes, N. T., Conwell, Y., & Cox, C. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00952-5 · Cited by 115 · see citing works
Sullivan, G. M., Oquendo, M. A., Milak, M., Miller, J. M., Burke, A., Ogden, R. T., Parsey, R. V., & Mann, J. J. (2015) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.2406 · Cited by 118 · see citing works
Arie, M., Apter, A., Orbach, I., Yefet, Y., & Zalzman, G. (2008) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2007.07.004 · Cited by 120 · see citing works
Postmortem Findings in Suicide Victims. Implications for <i>in Vivo</i> Imaging Studies<sup>a</sup>
ARANGO, V., UNDERWOOD, M. D., & MANN, J. J. (1997) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1997.tb52365.x · Cited by 106 · see citing works
Miller, J. M., Hesselgrave, N., Ogden, R. T., Sullivan, G. M., Oquendo, M. A., Mann, J. J., & Parsey, R. V. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.01.024 · Cited by 102 · see citing works
Brand, S., Moller, M., & Harvey, B. (2015) · Current Neuropharmacology · doi:10.2174/1570159x13666150307004545 · Cited by 95 · see citing works
Oquendo, M. A., Galfalvy, H., Sullivan, G. M., Miller, J. M., Milak, M. M., Sublette, M. E., Cisneros-Trujillo, S., Burke, A. K., Parsey, R. V., & Mann, J. J. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.1478 · Cited by 93 · see citing works
Horesh, N., Levi, Y., & Apter, A. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.11.035 · Cited by 88 · see citing works
Gvion, Y., Horresh, N., Levi-Belz, Y., Fischel, T., Treves, I., Weiser, M., David, H. S., Stein-Reizer, O., & Apter, A. (2014) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2013.09.003 · Cited by 87 · see citing works
Plasma serotonin levels and suicidal behavior in adolescents
Tyano, S., Zalsman, G., Ofek, H., Blum, I., Apter, A., Wolovik, L., Sher, L., Sommerfeld, E., Harell, D., & Weizman, A. (2006) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2005.05.005 · Cited by 66 · see citing works
Clinical Correlates of Planned and Unplanned Suicide Attempts
Chaudhury, S. R., Singh, T., Burke, A., Stanley, B., Mann, J. J., Grunebaum, M., Sublette, M. E., & Oquendo, M. A. (2016) · Journal of Nervous & Mental Disease · doi:10.1097/nmd.0000000000000502 · Cited by 48 · see citing works
Neurobiological aspects of suicide and suicide attempts in bipolar disorder
Mathews, D., Richards, E., Niciu, M., Ionescu, D., Rasimas, J., & Zarate, C. (2013) · Translational Neuroscience · doi:10.2478/s13380-013-0120-7 · Cited by 39 · see citing works
Gray matter volumetric study of major depression and suicidal behavior
Rizk, M. M., Rubin-Falcone, H., Lin, X., Keilp, J. G., Miller, J. M., Milak, M. S., Sublette, M. E., Oquendo, M. A., Ogden, R. T., Abdelfadeel, N. A., et al. (2019) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2018.11.007 · Cited by 35 · see citing works
Self-citationGovoni, S., Racchi, M., Masoero, E., Zamboni, M., & Ferini-Strambi, L. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000801 · Cited by 35 · see citing works
- Authors
- John Mann, J., & Malone, K. M.
- Affiliations
- New York State Psychiatric Institute (US)
- ORCID
- Malone, Kevin M.
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 1997-01
- Volume
- 41
- Issue
- 2
- Pages
- 162-171
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W1978805184
- Cited by
- 278
- References
- 63
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 1 · 2023: 4 · 2022: 4 · 2021: 6 · 2020: 7 · 2019: 3 · 2018: 9 · 2017: 6 · 2016: 9 · 2015: 9 · 2014: 10 · 2013: 15 · 2012: 6
- FWCI
- 18.45
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Biological Psychiatry (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (1r01mh040048-01)
- National Institute of Mental Health (MH-40048, MH48514, MH46745, R01MH048514)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Keywords
- suicide attempts, major depressive disorder, cerebrospinal fluid, 5-hydroxyindoleacetic acid, serotonergic activity, monoamine metabolites, lethality, suicide risk, hospitalized patients
- MeSH terms
- Adult, Depressive Disorder, Female, Homovanillic Acid, Humans, Hydroxyindoleacetic Acid, Male, Methoxyhydroxyphenylglycol, Middle Aged, Personality Inventory, Serotonin, Suicide, Attempted
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
