Inflammation, Glutamate, and Glia in Depression:A Literature Review

Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey Replication

Kessler, R. C., Berglund, P., Demler, O., Jin, R., Merikangas, K. R., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.593 · Cited by 20,391 · see citing works

Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication

Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.617 · Cited by 12,052 · see citing works

From inflammation to sickness and depression: when the immune system subjugates the brain

Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395 · see citing works

Stress and the brain: from adaptation to disease

de Kloet, E. R., Joëls, M., & Holsboer, F. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1683 · Cited by 4,621 · see citing works

Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study

Murray, C. J., & Lopez, A. D. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07495-8 · Cited by 4,492 · see citing works

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

Block, M. L., Zecca, L., & Hong, J.-S. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2038 · Cited by 4,110 · see citing works

Glutamate uptake

Danbolt, N. C. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(00)00067-8 · Cited by 4,068 · see citing works

Antidepressant effects of ketamine in depressed patients

Berman, R. M., Cappiello, A., Anand, A., Oren, D. A., Heninger, G. R., Charney, D. S., & Krystal, J. H. (2000) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00230-9 · Cited by 3,856 · see citing works

A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.

Zarate, C. A., Singh, J. B., Carlson, P. J., Brutsche, N. E., Ameli, R., Luckenbaugh, D. A., Charney, D. S., & Manji, H. K. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.8.856 · Cited by 3,766 · see citing works

Microglia: Active sensor and versatile effector cells in the normal and pathologic brain

Hanisch, U.-K., & Kettenmann, H. (2007) · Nature Neuroscience · doi:10.1038/nn1997 · Cited by 3,676 · see citing works

A Neurotrophic Model for Stress-Related Mood Disorders

Duman, R. S., & Monteggia, L. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.02.013 · Cited by 3,375 · see citing works

Cytokines sing the blues: inflammation and the pathogenesis of depression

Raison, C. L., Capuron, L., & Miller, A. H. (2006) · Trends in Immunology · doi:10.1016/j.it.2005.11.006 · Cited by 3,009 · see citing works

Knockout of Glutamate Transporters Reveals a Major Role for Astroglial Transport in Excitotoxicity and Clearance of Glutamate

Rothstein, J. D., Dykes-Hoberg, M., Pardo, C. A., Bristol, L. A., Jin, L., Kuncl, R. W., Kanai, Y., Hediger, M. A., Wang, Y., Schielke, J. P., et al. (1996) · Neuron · doi:10.1016/s0896-6273(00)80086-0 · Cited by 2,534 · see citing works

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

Qin, L., Wu, X., Block, M. L., Liu, Y., Breese, G. R., Hong, J., Knapp, D. J., & Crews, F. T. (2007) · Glia · doi:10.1002/glia.20467 · Cited by 2,144 · see citing works

Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1

Tanaka, K., Watase, K., Manabe, T., Yamada, K., Watanabe, M., Takahashi, K., Iwama, H., Nishikawa, T., Ichihara, N., Kikuchi, T., et al. (1997) · Science · doi:10.1126/science.276.5319.1699 · Cited by 1,755 · see citing works

Detection of circulating tumor necrosis factor after endotoxin administration

Michie, H. R., Manogue, K. R., Spriggs, D. R., Revhaug, A., O'Dwyer, S., Dinarello, C. A., Cerami, A., Wolff, S. M., & Wilmore, D. W. (1988) · New England Journal of Medicine · doi:10.1056/nejm198806093182301 · Cited by 1,677 · cited 1× · see citing works

Control of Synapse Number by Glia

Ullian, E. M., Sapperstein, S. K., Christopherson, K. S., & Barres, B. A. (2001) · Science · doi:10.1126/science.291.5504.657 · Cited by 1,380 · see citing works

Cytokine-Associated Emotional and Cognitive Disturbances in Humans

Reichenberg, A., Yirmiya, R., Schuld, A., Kraus, T., Haack, M., Morag, A., & Pollmächer, T. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.5.445 · Cited by 1,365 · see citing works

Gene-specific control of inflammation by TLR-induced chromatin modifications

Foster, S. L., Hargreaves, D. C., & Medzhitov, R. (2007) · Nature · doi:10.1038/nature05836 · Cited by 1,344 · see citing works

New insights into BDNF function in depression and anxiety

Martinowich, K., Manji, H., & Lu, B. (2007) · Nature Neuroscience · doi:10.1038/nn1971 · Cited by 1,221 · see citing works

Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial

Tyring, S., Gottlieb, A., Papp, K., Gordon, K., Leonardi, C., Wang, A., Lalla, D., Woolley, M., Jahreis, A., Zitnik, R., et al. (2006) · The Lancet · doi:10.1016/s0140-6736(05)67763-x · Cited by 1,069 · cited 1× · see citing works

The Relationship of Depression and Stressors to Immunological Assays: A Meta-Analytic Review

Zorrilla, E. P., Luborsky, L., McKay, J. R., Rosenthal, R., Houldin, A., Tax, A., McCorkle, R., Seligman, D. A., & Schmidt, K. (2001) · Brain, Behavior, and Immunity · doi:10.1006/brbi.2000.0597 · Cited by 995 · see citing works

Subtype-Specific Alterations of γ-Aminobutyric Acid and Glutamatein Patients With Major Depression

Sanacora, G., Gueorguieva, R. V., Epperson, C. N., Wu, Y., Appel, M., Rothman, D. L., Krystal, J. H., & Mason, G. F. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.7.705 · Cited by 796 · see citing works

The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine

Müller, N., Schwarz, M. J., Dehning, S., Douhe, A., Cerovecki, A., Goldstein-Müller, B., Spellmann, I., Hetzel, G., Maino, K., Kleindienst, N., et al. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001805 · Cited by 794 · see citing works

Excess mortality in depression: a meta-analysis of community studies

Cuijpers, P. J., & Smit, F. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(01)00413-x · Cited by 774 · see citing works

Glucocorticoids, depression, and mood disorders: Structural remodeling in the brain

McEwen, B. S. (2005) · Metabolism · doi:10.1016/j.metabol.2005.01.008 · Cited by 687 · see citing works

Depressive disorders and immunity: 20 years of progress and discovery

Irwin, M. R., & Miller, A. H. (2007) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.01.010 · Cited by 676 · see citing works

The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression

Müller, N., & Schwarz, M. J. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4002006 · Cited by 670 · see citing works

Neurotransmitter receptors on microglia

Pocock, J. M., & Kettenmann, H. (2007) · Trends in Neurosciences · doi:10.1016/j.tins.2007.07.007 · Cited by 650 · see citing works

Gliogenesis and Glial Pathology in Depression

Rajkowska, G., & Miguel-Hidalgo, J. J. (2007) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152707780619326 · Cited by 612 · see citing works

Inflammatory markers and depressed mood in older persons: results from the health, aging and body composition study

Penninx, B. W. J. H., Kritchevsky, S. B., Yaffe, K. S., Newman, A. B., Simonsick, E. M., Rubin, S. M., Ferrucci, L., Harris, T. B., & Pahor, M. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01811-5 · Cited by 530 · see citing works

Minocycline Provides Neuroprotection Against N -Methyl- d -aspartate Neurotoxicity by Inhibiting Microglia

Tikka, T., & Koıstınaho, J. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.12.7527 · Cited by 530 · see citing works

Kynurenine pathway in major depression: Evidence of impaired neuroprotection

Myint, A.-M., Kim, Y. K., Verkerk, R., Scharpé, S., Steinbusch, H., & Leonard, B. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.07.013 · Cited by 527 · see citing works

Interferon-alpha–induced changes in tryptophan metabolism

Capuron, L., Neurauter, G., Musselman, D. L., Lawson, D. H., Nemeroff, C. B., Fuchs, D., & Miller, A. H. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00173-2 · Cited by 493 · see citing works

Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease

Lobsiger, C. S., & Cleveland, D. W. (2007) · Nature Neuroscience · doi:10.1038/nn1988 · Cited by 438 · see citing works

Early Onset of Selective Serotonin Reuptake Inhibitor Antidepressant Action: Systematic Review and Meta-analysis

Taylor, M. J., Freemantle, N., Geddes, J. R., & Bhagwagar, Z. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.11.1217 · Cited by 406 · see citing works

Increased serum tumor necrosis factor-alpha levels and treatment response in major depressive disorder

Tuglu, C., Kara, S. H., Caliyurt, O., Vardar, E., & Abay, E. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1566-z · Cited by 391 · see citing works

Cytokine–serotonin interaction through IDO: a neurodegeneration hypothesis of depression

Myint, A.-M., & Kim, Y. K. (2003) · Medical Hypotheses · doi:10.1016/s0306-9877(03)00207-x · Cited by 376 · see citing works

Th1, Th2, and Th3 cytokine alterations in major depression

MYINT, A., LEONARD, B., STEINBUSCH, H., & KIM, Y. (2005) · Journal of Affective Disorders · doi:10.1016/j.jad.2005.07.008 · Cited by 371 · see citing works

Effects of antidepressants on the production of cytokines

Kenis, G., & Maes, M. (2002) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145702003164 · Cited by 370 · see citing works

Cerebrospinal Cytokine Levels in Patients with Acute Depression

Levine, J., Barak, Y., Chengappa, K. N. R., Rapoport, A., Rebey, M., & Barak, V. (1999) · Neuropsychobiology · doi:10.1159/000026615 · Cited by 354 · see citing works

Resolution of Sleepiness and Fatigue in Major Depressive Disorder: A Comparison of Bupropion and the Selective Serotonin Reuptake Inhibitors

Papakostas, G. I., Nutt, D., Hallett, L. A., Tucker, V. L., Krishen, A., & D, M. F. M. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.06.015 · Cited by 334 · see citing works

The immune system, depression and the action of antidepressants

Leonard, B. E. (2001) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(01)00155-5 · Cited by 333 · see citing works

Inflammatory markers in late-life depression: Results from a population-based study

Bremmer, M. A., Beekman, A. T. F., Deeg, D. J. H., Penninx, B. W. J. H., Dik, M. G., Hack, C. E., & Hoogendijk, W. J. G. (2007) · Journal of Affective Disorders · doi:10.1016/j.jad.2007.07.002 · Cited by 326 · see citing works

An Open-Label Trial of Riluzole in Patients With Treatment-Resistant Major Depression

Zarate, C. A., Payne, J. L., Quiroz, J. A., Sporn, J., Denicoff, K. K., Luckenbaugh, D. A., Charney, D. S., & Manji, H. K. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.1.171 · Cited by 324 · see citing works

Reduction in Occipital Cortex γ-Aminobutyric Acid Concentrations in Medication-Free Recovered Unipolar Depressed and Bipolar Subjects

Bhagwagar, Z., Wylezinska, M., Jezzard, P., Evans, J., Ashworth, F., Sule, A., Matthews, P. M., & Cowen, P. J. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.08.048 · Cited by 304 · see citing works

Glial Contribution to Glutamate Uptake at Schaffer Collateral–Commissural Synapses in the Hippocampus

Bergles, D. E., & Jahr, C. E. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-19-07709.1998 · Cited by 298 · see citing works

Pro-inflammatory cytokines and treatment response to escitaloprsam in major depressive disorder

Eller, T., Vasar, V., Shlik, J., & Maron, E. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.09.015 · Cited by 290 · see citing works

Acute inflammation and negative mood: mediation by cytokine activation

Wright, C. E., Strike, P. C., Brydon, L., & Steptoe, A. (2005) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2004.10.003 · Cited by 287 · see citing works

Neurohormonal-cytokine interactions: implications for inflammation, common human diseases and well-being

Elenkov, I. J. (2008) · Neurochemistry International · doi:10.1016/j.neuint.2007.06.037 · Cited by 273 · see citing works

Alterations of neuroplasticity in depression: the hippocampus and beyond

Fuchs, E., Czéh, B., Kole, M. H. P., Michaelis, T., & Lucassen, P. J. (2004) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2004.09.002 · Cited by 271 · see citing works

Age-Dependent Reductions in the Level of Glial Fibrillary Acidic Protein in the Prefrontal Cortex in Major Depression

Si, X., Miguel-Hidalgo, J. J., O'Dwyer, G., Stockmeier, C. A., & Rajkowska, G. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300525 · Cited by 268 · see citing works

Cancer-related fatigue: Links with inflammation in cancer patients and survivors

Bower, J. E. (2007) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2007.03.013 · Cited by 256 · see citing works

TNFα Signaling in Depression and Anxiety: Behavioral Consequences of Individual Receptor Targeting

Simen, B. B., Duman, C. H., Simen, A. A., & Duman, R. S. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.10.013 · Cited by 249 · see citing works

Raised Plasma Levels of Tumor Necrosis Factor α in Patients With Depression: Normalization During Electroconvulsive Therapy

Hestad, K. A., Tønseth, S., Støen, C. D., Ueland, T., & Aukrust, P. (2003) · The Journal of ECT · doi:10.1097/00124509-200312000-00002 · Cited by 235 · see citing works

Basal Ganglia Hypermetabolism and Symptoms of Fatigue during Interferon-α Therapy

Capuron, L., Pagnoni, G., Demetrashvili, M. F., Lawson, D. H., Fornwalt, F. B., Woolwine, B., Berns, G. S., Nemeroff, C. B., & Miller, A. H. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301362 · Cited by 229 · see citing works

Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs

Pałucha-Poniewiera, A., & Pilc, A. (2007) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2007.04.007 · Cited by 220 · see citing works

Riluzole Enhances Glutamate Uptake in Rat Astrocyte Cultures

Frizzo, M. E., Dall’Onder, L. P., Dalcin, K. B., & Souza, D. O. (2004) · Cellular and Molecular Neurobiology · doi:10.1023/b:cemn.0000012717.37839.07 · Cited by 213 · see citing works

Inflammation and interleukin-1 signaling network contribute to depressive symptoms but not cognitive decline in old age

van den Biggelaar, A. H. J., Gussekloo, J., de Craen, A. J. M., Frölich, M., Stek, M. L., van der Mast, R. C., & Westendorp, R. G. J. (2007) · Experimental Gerontology · doi:10.1016/j.exger.2007.01.011 · Cited by 209 · see citing works

The NMDA Receptor as a Therapeutic Target in Major Depressive Disorder

Pittenger, C., Sanacora, G., & Krystal, J. H. (2007) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152707780363267 · Cited by 203 · see citing works

Glia‐derived signals induce synapse formation in neurones of the rat central nervous system

Nägler, K., Mauch, D. H., & Pfrieger, F. W. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.00665.x · Cited by 203 · see citing works

Preliminary Evidence of Riluzole Efficacy in Antidepressant-Treated Patients with Residual Depressive Symptoms

Sanacora, G., Kendell, S. F., Levin, Y., Simen, A. A., Fenton, L. R., Coric, V., & Krystal, J. H. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.08.037 · Cited by 199 · see citing works

Antidepressants inhibit interferon-γ-induced microglial production of IL-6 and nitric oxide

Hashioka, S., Klegeris, A., Monji, A., Kato, T., Sawada, M., McGeer, P. L., & Kanba, S. (2007) · Experimental Neurology · doi:10.1016/j.expneurol.2007.03.022 · Cited by 198 · see citing works

Psychiatric Epidemiology: It’s Not Just About Counting Anymore

Insel, T. R., & Fenton, W. S. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.590 · Cited by 198 · see citing works

A mechanism for increased quinolinic acid formation following acute systemic immune stimulation.

Saito, K., Crowley, J. S., Markey, S., & Heyes, M. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)82284-0 · Cited by 194 · see citing works

Altered Glutamate Reuptake in Relapsing-Remitting and Secondary Progressive Multiple Sclerosis Cortex: Correlation With Microglia Infiltration, Demyelination, and Neuronal and Synaptic Damage

Vercellino, M., Merola, A., Piacentino, C., Votta, B., Capello, E., Mancardi, G. L., Mutani, R., Giordana, M. T., & Cavalla, P. (2007) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0b013e31812571b0 · Cited by 190 · see citing works

Inflammation in Human Brain Injury: Intracerebral Concentrations of IL-1 α , IL-1 β , and Their Endogenous Inhibitor IL-1ra

Hutchinson, P. J., O’Connell, M. T., Rothwell, N. J., Hopkins, S. J., Nortje, J., Carpenter, K. L. H., Timofeev, I. S., Al-Rawi, P. G., Menon, D. K., & Pickard, J. D. (2007) · Journal of Neurotrauma · doi:10.1089/neu.2007.0295 · Cited by 185 · see citing works

Interferon-Induced Depression in Chronic Hepatitis C: A Review of Its Prevalence, Risk Factors, Biology, and Treatment Approaches

Asnis, G. M., & Garza, R. D. L. (2006) · Journal of Clinical Gastroenterology · doi:10.1097/01.mcg.0000210099.36500.fe · Cited by 170 · see citing works

Major depression and all-cause mortality among white adults in the United States

Zheng, D., Macera, C. A., Croft, J. B., Giles, W. H., Davis, D. R., & Scott, W. K. (1997) · Annals of Epidemiology · doi:10.1016/s1047-2797(97)00014-8 · Cited by 169 · see citing works

Medical Co-Morbidity in Depressive Disorders

Benton, T. D., Staab, J. P., & Evans, D. L. (2007) · Annals of Clinical Psychiatry · doi:10.1080/10401230701653542 · Cited by 164 · see citing works

Memantine protects against LPS-induced neuroinflammation, restores behaviorally-induced gene expression and spatial learning in the rat

Rosi, S., Vazdarjanova, A. I., Ramı́rez-Amaya, V., Worley, P. F., Barnes, C. A., & Wenk, G. L. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.017 · Cited by 158 · see citing works

Mood Alterations During Interferon-Alfa Therapy in Patients With Chronic Hepatitis C

Constant, A., Castéra, L., Dantzer, R., Couzigou, P., de Lédinghen, V., Demotes‐Mainard, J., & Henry, C. (2005) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v66n0814 · Cited by 151 · see citing works

Dose‐Related Inflammatory Effects of Intravenous Endotoxin in Humans: Evaluation of a New Clinical Lot ofEscherichia coliO:113 Endotoxin

Suffredini, A. F., Hochstein, H. D., & McMahon, F. G. (1999) · The Journal of Infectious Diseases · doi:10.1086/314717 · Cited by 151 · see citing works

Prefrontal cortical hypometabolism during low-dose interferon alpha treatment

Juengling, F. D., Ebert, D., Gut, O., Engelbrecht, M. A., Rasenack, J., Nitzsche, E. U., Bauer, J., & Lieb, K. (2000) · Psychopharmacology · doi:10.1007/s002130000549 · Cited by 149 · see citing works

Quinolinate neurotoxicity in cortical cell culture

Kim, J. P., & Choi, D. W. (1987) · Neuroscience · doi:10.1016/0306-4522(87)90066-2 · Cited by 144 · see citing works

Glial fibrillary acidic protein is reduced in cerebellum of subjects with major depression, but not schizophrenia

Fatemi, S. H., Laurence, J. A., Araghi‐Niknam, M., Stary, J. M., Schulz, S. C., Lee, S. S., & Gottesman, I. I. (2003) · Schizophrenia Research · doi:10.1016/j.schres.2003.08.014 · Cited by 141 · see citing works

Negative Emotions and 3-Year Progression of Subclinical Atherosclerosis

Stewart, J. C., Janicki, D. L., Muldoon, M. F., Sutton-Tyrrell, K., & Kamarck, T. W. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.2.225 · Cited by 137 · see citing works

Phase-dependent roles of reactive microglia and astrocytes in nervous system injury as delineated by imaging of peripheral benzodiazepine receptor

Maeda, J., Higuchi, M., Inaji, M., Ji, B., Haneda, E., Okauchi, T., Zhang, M., Suzuki, K., & Suhara, T. (2007) · Brain Research · doi:10.1016/j.brainres.2007.04.054 · Cited by 134 · see citing works

Tryptophan Depletion, Serotonin, and Depression: Where Do We Stand?

Neumeister, A. (2025) · Psychopharmacology Bulletin · doi:10.64719/pb.4167 · Cited by 130 · see citing works

Untitled work

(1998) · PubMed · Cited by 121 · see citing works

Neuroprotective actions of endogenous interleukin‐1 receptor antagonist (IL‐1ra) are mediated by glia

Pinteaux, E., Rothwell, N. J., & Boutin, H. (2005) · Glia · doi:10.1002/glia.20308 · Cited by 117 · see citing works

The function of microglia, either neuroprotection or neurotoxicity, is determined by the equilibrium among factors released from activated microglia in vitro

Li, L., Lu, J., Tay, S. S. W., Moochhala, S., & He, B. P. (2007) · Brain Research · doi:10.1016/j.brainres.2007.04.066 · Cited by 110 · see citing works

Effects of ketamine and propofol on inflammatory responses of primary glial cell cultures stimulated with lipopolysaccharide

Shibakawa, Y. S., Sasaki, Y., Goshima, Y., Echigo, N., Kamiya, Y., Kurahashi, K., Yamada, Y., & Andoh, T. (2005) · British Journal of Anaesthesia · doi:10.1093/bja/aei256 · Cited by 96 · see citing works

Biological variations, genetic polymorphisms and familial resemblance of TNF-α and IL-6 concentrations: STANISLAS cohort

Haddy, N., Sass, C., Maumus, S., Bastien, B., Droesch, S., Siest, G., Lambert, D., & Visvikis‐Siest, S. (2004) · European Journal of Human Genetics · doi:10.1038/sj.ejhg.5201294 · Cited by 81 · see citing works

Overexpression of IL-1β by adenoviral-mediated gene transfer in the rat brain causes a prolonged hepatic chemokine response, axonal injury and the suppression of spontaneous behaviour

Campbell, S. J., Deacon, R. M. J., Jiang, Y., Ferrari, C. C., Pitossi, F. J., & Anthony, D. C. (2007) · Neurobiology of Disease · doi:10.1016/j.nbd.2007.04.013 · Cited by 60 · see citing works

Depression and ischemic heart disease: what have we learned from clinical trials?

Rivelli, S. K., & Jiang, W. (2007) · Current Opinion in Cardiology · doi:10.1097/hco.0b013e3281ead011 · Cited by 42 · see citing works

Autocrine activation of cultured macrophages by brain-derived neurotrophic factor

Asami, T., Ito, T., Fukumitsu, H., Nomoto, H., Furukawa, Y., & Furukawa, S. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.03.228 · Cited by 42 · see citing works

Caspase 1 deficiency reduces inflammation-induced brain transcription

Mastronardi, C. A., Whelan, F., Yildiz, O. A., Hannestad, J. O., Elashoff, D. A., McCann, S. M., Licinio, J., & Wong, M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0701366104 · Cited by 42 · see citing works

Interferon-α reduces the density of monoaminergic axons in the rat brain

Ishikawa, J., Ishikawa, A., & Nakamura, S. (2007) · Neuroreport · doi:10.1097/wnr.0b013e328010231a · Cited by 41 · see citing works

Expression of the TrkB neurotrophin receptor by thymic macrophages

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