Subjective Cognitive Complaints Contribute to Misdiagnosis of Mild Cognitive Impairment

Edmonds, Emily C.; Delano-Wood, Lisa; Galasko, Douglas R.; Salmon, David P.; Bondi, Mark W.

doi:10.1017/s135561771400068x

Cited by 249Dementia and Cognitive Impairment ResearchCancer-related cognitive impairment studiesCognitive Functions and Memory

Subjective Cognitive Complaints Contribute to Misdiagnosis of Mild Cognitive Impairment

Open access

Edmonds, Emily C., Delano-Wood, Lisa, Galasko, Douglas R., Salmon, David P., Bondi, Mark W.·2014·Journal of the International Neuropsychological Society

DOI 10.1017/s135561771400068xPMC PMC4172502

Open this paper in CoChat — free account

Abstract

Subjective cognitive complaints are a criterion for the diagnosis of mild cognitive impairment (MCI), despite their uncertain relationship to objective memory performance in MCI. We aimed to examine self-reported cognitive complaints in subgroups of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) MCI cohort to determine whether they are a valuable inclusion in the diagnosis of MCI or, alternatively, if they contribute to misdiagnosis. Subgroups of MCI were derived using cluster analysis of baseline neuropsychological test data from 448 ADNI MCI participants. Cognitive complaints were assessed via the Everyday Cognition (ECog) questionnaire, and discrepancy scores were calculated between self- and informant-report. Cluster analysis revealed Amnestic and Mixed cognitive phenotypes as well as a third Cluster-Derived Normal subgroup (41.3%), whose neuropsychological and cerebrospinal fluid (CSF) Alzheimer’s disease (AD) biomarker profiles did not differ from a “robust” normal control group. This cognitively intact phenotype of MCI participants overestimated their cognitive problems relative to their informant, whereas Amnestic MCI participants with objective memory impairment underestimated their cognitive problems. Underestimation of cognitive problems was associated with positive CSF AD biomarkers and progression to dementia. Overall, there was no relationship between self-reported cognitive complaints and objective cognitive functioning, but significant correlations were observed with depressive symptoms. The inclusion of self-reported complaints in MCI diagnostic criteria may cloud rather than clarify diagnosis and result in high rates of misclassification of MCI. Discrepancies between self- and informant-report demonstrate that overestimation of cognitive problems is characteristic of normal aging while underestimation may reflect greater risk for cognitive decline. (JINS, 2014,20, 1–12)

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1017/s135561771400068x

Cites

46 of 46 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

About a third of MCI subjects have shown to be incorrectly diagnosed with cognitive impairment.
“We chose to include MCI subjects in addition to healthy controls since the cognitive impairment did not necessarily have to be caused by an underlying AD process and because about a third of MCI subjects have shown to be incorrectly diagnosed with cognitive impairment43–45.”
From Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity (2017) · cites this paper as [45]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
McKhann, G. M., Knopman, D. S., Chertkow, H., Hyman, B. T., Jack, C. R., Kawas, C. H., Klunk, W. E., Koroshetz, W. J., Manly, J. J., Mayeux, R., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.005 · Cited by 18,657 · see citing works
The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Albert, M. S., DeKosky, S. T., Dickson, D., Dubois, B., Feldman, H. H., Fox, N. C., Gamst, A., Holtzman, D. M., Jagust, W. J., Petersen, R. C., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.008 · Cited by 10,152 · cited 1× · see citing works
“There is also variability in the source of the subjective complaint or concern, as it can be obtained from either the patient, an informant, or a skilled clinician (Albert et al., 2011; Petersen et al., 2010).”
The Clinical Dementia Rating (CDR): Current version and scoring rules
Morris, J. C. (1993) · Neurology · doi:10.1212/wnl.43.11.2412-a · Cited by 9,882 · see citing works
Mild cognitive impairment as a diagnostic entity
Petersen, R. C. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01388.x · Cited by 7,864 · see citing works
Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease
Sperling, R. A., Aisen, P. S., Beckett, L. A., Bennett, D. A., Craft, S., Fagan, A. M., Iwatsubo, T., Jack, C. R., Kaye, J., Montine, T. J., et al. (2011) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.03.003 · Cited by 7,155 · see citing works
Mild cognitive impairment – Beyond controversies, towards a consensus: Report of the International Working Group on Mild Cognitive Impairment.
Winblad, B., Palmer, K., Kivipelto, M., Jelic, V., Fratiglioni, L., Wahlund, L. ‐., Nordberg, A., Bäckman, L., Albert, M., Almkvist, O., et al. (2004) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2004.01380.x · Cited by 4,946 · see citing works
The Diagnosis of Mild Cognitive Impairment due to Alzheimer’s Disease: Recommendations from the National Institute on Aging-Alzheimer’s Association Workgroups on Diagnostic Guidelines for Alzheimer’s Disease
Albert, M., DeKosky, S. T., Dickson, D. W., Dubois, B., Feldman, H., Fox, N. C., Gamst, A. C., Holtzman, D. M., Jagust, W. J., Petersen, R. C., et al. (2013) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.11.1.96 · Cited by 2,630 · see citing works
Alzheimer's Disease Neuroimaging Initiative (ADNI)
Petersen, R. C., Aisen, P. S., Beckett, L. A., Donohue, M. C., Gamst, A. C., Harvey, D. J., Jack, C. R., Jagust, W. J., Shaw, L. M., Toga, A. W., et al. (2010) · Neurology · doi:10.1212/wnl.0b013e3181cb3e25 · Cited by 2,572 · cited 3× · see citing works
“diagnosed with MCI based on conventional diagnostic criteria adapted for ADNI (Petersen &Morris, 2005; Petersen et al., 2010).”
Wechsler Memory Scale-Revised
Peter, H., Penzel, T., Peter, J. H., & Peter, J. G. (2025) · Springer Reference Medizin · doi:10.1007/978-3-662-65186-5_302294 · Cited by 2,278 · see citing works
Wechsler memory scale-revised
Reynolds, C. R., & Powel, J. (1988) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/3.4.397 · Cited by 2,115 · see citing works
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
Shaw, L. M., Vanderstichele, H., Knapik‐Czajka, M., Clark, C. M., Aisen, P. S., Petersen, R. C., Blennow, K., Soares, H., Simon, A., Lewczuk, P., et al. (2009) · Annals of Neurology · doi:10.1002/ana.21610 · Cited by 2,065 · see citing works
Mild Cognitive Impairment as a Clinical Entity and Treatment Target
Petersen, R. C., & Morris, J. C. (2005) · Archives of Neurology · doi:10.1001/archneur.62.7.1160 · Cited by 935 · see citing works
Neuropsychological Criteria for Mild Cognitive Impairment Improves Diagnostic Precision, Biomarker Associations, and Progression Rates
Bondi, M. W., Initiative, F. T. A. D. N., Edmonds, E. C., Jak, A. J., Clark, L. R., Delano-Wood, L., McDonald, C. R., Nation, D. A., Libon, D. J., Au, R., et al. (2014) · Journal of Alzheimer's Disease · doi:10.3233/jad-140276 · Cited by 750 · see citing works
Self-citation
The measurement of everyday cognition (ECog): Scale development and psychometric properties.
Farias, S. T., Mungas, D., Reed, B., Cahn, D. A., Jagust, W. J., Baynes, K., & DeCarli, C. S. (2008) · Neuropsychology · doi:10.1037/0894-4105.22.4.531 · Cited by 637 · see citing works
Subjective Memory Complaints and Cognitive Impairment in Older People
Reid, L. M., & MacLullich, A. M. J. (2006) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000096295 · Cited by 633 · see citing works
Comparing predictors of conversion and decline in mild cognitive impairment
Landau, S. M., Harvey, D., Madison, C. M., Reiman, E. M., Foster, N. L., Aisen, P. S., Petersen, R. C., Shaw, L. M., Trojanowski, J. Q., Jack, C. R., et al. (2010) · Neurology · doi:10.1212/wnl.0b013e3181e8e8b8 · Cited by 616 · see citing works
Functional deficits in patients with mild cognitive impairment
Tabert, M. H., Albert, S. M., Borukhova-Milov, L., Camacho, Y., Pelton, G. H., Liu, X., Stern, Y., & Devanand, D. P. (2002) · Neurology · doi:10.1212/wnl.58.5.758 · Cited by 479 · see citing works
Reversion from mild cognitive impairment to normal or near-normal cognition: Risk factors and prognosis
Koepsell, T. D., & Monsell, S. E. (2012) · Neurology · doi:10.1212/wnl.0b013e31826e26b7 · Cited by 369 · see citing works
Outcomes of Mild Cognitive Impairment by Definition
Ganguli, M., Snitz, B. E., Saxton, J. A., Chang, C.-C. H., Lee, C.-W., Bilt, J. V., Hughes, T. F., Loewenstein, D., Unverzagt, F. W., & Petersen, R. C. (2011) · Archives of Neurology · doi:10.1001/archneurol.2011.101 · Cited by 284 · see citing works
Awareness of Deficits in Mild Cognitive Impairment and Alzheimer’s Disease: Do MCI Patients Have Impaired Insight?
Vogel, A., Stokholm, J., Gade, A., Andersen, B. B., Hejl, A., & Waldemar, G. (2004) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000076354 · Cited by 280 · see citing works
Degree of discrepancy between self and other‐reported everyday functioning by cognitive status: dementia, mild cognitive impairment, and healthy elders
Farias, S. T., Mungas, D., & Jagust, W. J. (2005) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.1367 · Cited by 278 · see citing works
Neuropsychological tests accurately predict incident Alzheimer disease after 5 and 10 years
Tierney, M. C., Yao, C., Kiss, A., & McDowell, I. (2005) · Neurology · doi:10.1212/01.wnl.0000163773.21794.0b · Cited by 274 · see citing works
Mild cognitive impairment due to Alzheimer disease in the community
Petersen, R. C., Aisen, P., Boeve, B. F., Geda, Y. E., Ivnik, R. J., Knopman, D. S., Mielke, M., Pankratz, V. S., Roberts, R., Rocca, W. A., et al. (2013) · Annals of Neurology · doi:10.1002/ana.23931 · Cited by 265 · see citing works
Sensitivity and specificity of neuropsychological tests for mild cognitive impairment, vascular cognitive impairment and Alzheimer's disease
DE JAGER, C. A., HOGERVORST, E., COMBRINCK, M., & BUDGE, M. M. (2003) · Psychological Medicine · doi:10.1017/s0033291703008031 · Cited by 259 · see citing works
Susceptibility of the conventional criteria for mild cognitive impairment to false‐positive diagnostic errors
Edmonds, E. C., Delano‐Wood, L., Clark, L. R., Jak, A. J., Nation, D. A., McDonald, C. R., Libon, D. J., Au, R., Galasko, D., Salmon, D. P., et al. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.03.005 · Cited by 256 · see citing works
Self-citation
Differential Memory Test Sensitivity for Diagnosing Amnestic Mild Cognitive Impairment and Predicting Conversion to Alzheimer's Disease
Rabin, L. A., Paré, N., Saykin, A. J., Brown, M. J., Wishart, H. A., Flashman, L. A., & Santulli, R. B. (2009) · Aging, Neuropsychology, and Cognition · doi:10.1080/13825580902825220 · Cited by 256 · see citing works
Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease.
Bondi, M. W., Salmon, D. P., Galasko, D., Thomas, R. G., & Thal, L. J. (1999) · Psychology and Aging · doi:10.1037//0882-7974.14.2.295 · Cited by 235 · see citing works
Self-citation
Subjective Memory Complaints and Awareness of Memory Functioning in Mild Cognitive Impairment: A Systematic Review
Roberts, J. L., Clare, L., & Woods, B. T. (2009) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000234911 · Cited by 220 · see citing works
The Effects of Preclinical Dementia on Estimates of Normal Cognitive Functioning in Aging
Sliwinski, M. J., Lipton, R. B., Herman Buschke, L., & Stewart, W. F. (1996) · The Journals of Gerontology Series B · doi:10.1093/geronb/51b.4.p217 · Cited by 216 · see citing works
Factors affecting subjective memory complaints in the AIBL aging study: biomarkers, memory, affect, and age
Buckley, R., Saling, M. M., Ames, D., Rowe, C. C., Lautenschlager, N. T., Macaulay, S. L., Martins, R. N., Masters, C. L., O'Meara, T., Savage, G., et al. (2013) · International Psychogeriatrics · doi:10.1017/s1041610213000665 · Cited by 173 · see citing works
Neuropsychological measures predict decline to Alzheimer's dementia from mild cognitive impairment.
Summers, M. J., & Saunders, N. L. (2012) · Neuropsychology · doi:10.1037/a0028576 · Cited by 172 · see citing works
Neuropsychological function and apolipoprotein E genotype in the preclinical detection of Alzheimer's disease.
Bondi, M. W., Salmon, D. P., Galasko, D. R., et al. (1999) · Psychology and Aging · doi:10.1037/0882-7974.14.2.295 · Cited by 170 · see citing works
Self-citation
Are Empirically-Derived Subtypes of Mild Cognitive Impairment Consistent with Conventional Subtypes?
Clark, L. R., Delano-Wood, L., Libon, D. J., McDonald, C. R., Nation, D. A., Bangen, K. J., Jak, A. J., Au, R., Salmon, D. P., & Bondi, M. W. (2013) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617713000313 · Cited by 167 · see citing works
Self-citation
The source of cognitive complaints predicts diagnostic conversion differentially among nondemented older adults
Gifford, K. A., Liu, D., Lu, Z., Tripodis, Y., Cantwell, N. G., Palmisano, J. N., Kowall, N. W., & Jefferson, A. L. (2013) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2013.02.007 · Cited by 160 · see citing works
Heterogeneity in mild cognitive impairment: Differences in neuropsychological profile and associated white matter lesion pathology
DELANO-WOOD, L., BONDI, M. W., SACCO, J., ABELES, N., JAK, A. J., LIBON, D. J., & BOZOKI, A. (2009) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617709990257 · Cited by 155 · cited 2× · see citing works
“…demonstrate deficits primarily in one area of cognitive ability (e.g., memory, executive functioning, language), while others demonstrate impairments in multiple cognitive domains (Bondi et al., 2014; Clark et al., 2013; Delano-Wood et al., 2009; Edmonds et al., 2014; Libon et al., 2010).”
Self-citation
Base Rates of “Impaired” Neuropsychological Test Performance Among Healthy Older Adults
Palmer, B. (1998) · Archives of Clinical Neuropsychology · doi:10.1016/s0887-6177(97)00037-1 · Cited by 142 · see citing works
Substantial risk of “Accidental MCI” in healthy older adults: Base rates of low memory scores in neuropsychological assessment
BROOKS, B. L., IVERSON, G. L., & WHITE, T. (2007) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617707070531 · Cited by 140 · see citing works
Chronic Postconcussion Symptoms and Functional Outcomes in OEF/OIF Veterans with Self-Report of Blast Exposure
Verfaellie, M. H., Lafleche, G., Spiro, A., Tun, C. G., & Bousquet, K. (2012) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617712000902 · Cited by 134 · see citing works
The heterogeneity of mild cognitive impairment: A neuropsychological analysis
LIBON, D. J., XIE, S. X., EPPIG, J., WICAS, G., LAMAR, M., LIPPA, C., BETTCHER, B. M., PRICE, C. C., GIOVANNETTI, T., SWENSON, R., et al. (2010) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617709990993 · Cited by 130 · see citing works
Effect of Knowledge of APOE Genotype on Subjective and Objective Memory Performance in Healthy Older Adults
Lineweaver, T. T., Bondi, M. W., Galasko, D. R., & Salmon, D. P. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2013.12121590 · Cited by 127 · see citing works
Self-citation
Absence of a relationship between subjective memory complaint and objective memory impairment in mild cognitive impairment (MCI): is it time to abandon subjective memory complaint as an MCI diagnostic criterion?
Lenehan, M. E., Klekociuk, S. Z., & Summers, M. J. (2012) · International Psychogeriatrics · doi:10.1017/s1041610212000695 · Cited by 119 · see citing works
Everyday Cognition in Older Adults: Associations with Neuropsychological Performance and Structural Brain Imaging
Farias, S. T., Park, L. Q., Harvey, D. J., Simon, C., Reed, B., Carmichael, O. T., & Mungas, D. (2013) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617712001609 · Cited by 108 · see citing works
Functional and cognitive criteria produce different rates of mild cognitive impairment and conversion to dementia
Saxton, J., Snitz, B. E., Lopez, O. L., Ives, D. G., Dunn, L. O., Fitzpatrick, A., Carlson, M. C., DeKosky, S. T., & for the GEM Study Investigators (2009) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.2008.160705 · Cited by 106 · see citing works
Regional White Matter Pathology in Mild Cognitive Impairment
Delano‐Wood, L., Abeles, N., Sacco, J. M., Wierenga, C. E., Horne, N. R., & Bozoki, A. (2008) · Stroke · doi:10.1161/strokeaha.107.502534 · Cited by 106 · see citing works
Self-citation
Psychological Testing
B., H., & Mursell, J. L. (1948) · Population · doi:10.2307/1523830 · Cited by 89 · see citing works
Subjective cognitive decline in patients with mild cognitive impairment and healthy older adults: Association with personality traits
Studer, J., Donati, A., Popp, J., & von Gunten, A. (2013) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/ggi.12139 · Cited by 46 · see citing works

Flagged first, then by citations

Sorted by citations

Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity
Palmqvist, S., Schöll, M., Strandberg, O., Mattsson, N., Stomrud, E., Zetterberg, H., Blennow, K., Landau, S., Jagust, W., & Hansson, O. (2017) · Nature Communications · doi:10.1038/s41467-017-01150-x · Cited by 911 · see citing works
Implementation of subjective cognitive decline criteria in research studies
Molinuevo, J. L., Rabin, L. A., Amariglio, R., Buckley, R., Dubois, B., Ellis, K. A., Ewers, M., Hampel, H., Klöppel, S., Rami, L., et al. (2017) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2016.09.012 · Cited by 575 · see citing works
State of the science on mild cognitive impairment (MCI)
Anderson, N. D. (2019) · CNS Spectrums · doi:10.1017/s1092852918001347 · Cited by 547 · see citing works
American Academy of Clinical Neuropsychology (AACN) 2021 consensus statement on validity assessment: Update of the 2009 AACN consensus conference statement on neuropsychological assessment of effort, response bias, and malingering
Sweet, J. J., Heilbronner, R. L., Morgan, J. E., Larrabee, G. J., Rohling, M. L., Boone, K. B., Kirkwood, M. W., Schroeder, R. W., Suhr, J. A., & Participants, C. (2021) · The Clinical Neuropsychologist · doi:10.1080/13854046.2021.1896036 · Cited by 486 · see citing works
Subjective Cognitive Decline in Older Adults: An Overview of Self-Report Measures Used Across 19 International Research Studies
Rabin, L. A., Initiative, T. A. D. N., Smart, C. M., Crane, P. K., Amariglio, R. E., Berman, L., Boada, M., Buckley, R. F., Chételat, G., Dubois, B., et al. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150154 · Cited by 472 · see citing works
Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials
Weiner, M. W., Veitch, D. P., Aisen, P. S. S., Beckett, L. A., Cairns, N. J., Green, R. C., Harvey, D. J., Jack, C. R., Jagust, W. J., Morris, J. C., et al. (2017) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2016.11.007 · Cited by 314 · see citing works
Subjective Cognitive Impairment and Affective Symptoms: A Systematic Review
Hill, N. L., Mogle, J., Wion, R., Munoz, E., DePasquale, N., Yevchak, A. M., & Parisi, J. M. (2016) · The Gerontologist · doi:10.1093/geront/gnw091 · Cited by 277 · see citing works
Subtle Cognitive Decline and Biomarker Staging in Preclinical Alzheimer’s Disease
Edmonds, E. C., Initiative, A. D. N., Delano‐Wood, L., Galasko, D. R., Salmon, D. P., & Bondi, M. W. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150128 · Cited by 195 · see citing works
Self-citation
Consideration of sex and gender in Alzheimer's disease and related disorders from a global perspective
Mielke, M. M., Aggarwal, N. T., Vila‐Castelar, C., Agarwal, P., Arenaza‐Urquijo, E. M., Brett, B., Brugulat‐Serrat, A., DuBose, L. E., Eikelboom, W. S., Flatt, J., et al. (2022) · Alzheimer's & Dementia · doi:10.1002/alz.12662 · Cited by 198 · see citing works
Neuropsychological Criteria for Mild Cognitive Impairment and Dementia Risk in the Framingham Heart Study
Jak, A. J., Preis, S. R., Beiser, A., Seshadri, S. S., Wolf, P. A., Bondi, M. W., & Au, R. (2016) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617716000199 · Cited by 147 · see citing works
Self-citation
The Cognitive Change Index as a Measure of Self and Informant Perception of Cognitive Decline: Relation to Neuropsychological Tests
Rattanabannakit, C., Risacher, S. L., Gao, S., Lane, K. A., Brown, S. A., McDonald, B. C., Unverzagt, F. W., Apostolova, L. G., Saykin, A. J., & Farlow, M. R. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-150729 · Cited by 146 · see citing works
Early versus late MCI: Improved MCI staging using a neuropsychological approach
Edmonds, E. C., McDonald, C. R., Marshall, A. J., Thomas, K. R., Eppig, J. S., Weigand, A. J., Delano‐Wood, L., Galasko, D. R., Salmon, D. P., Bondi, M. W., et al. (2019) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2018.12.009 · Cited by 143 · see citing works
Self-citation
Prevalence and Incidence of Mild Cognitive Impairment across Subtypes, Age, and Sex
Overton, M., Pihlsgård, M., & Elmståhl, S. (2019) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000499763 · Cited by 134 · see citing works
Dementia worry and its relationship to dementia exposure, psychological factors, and subjective memory concerns
Kinzer, A., & Suhr, J. A. (2016) · Applied Neuropsychology: Adult · doi:10.1080/23279095.2015.1030669 · Cited by 107 · see citing works
Differential Risk of Incident Alzheimer’s Disease Dementia in Stable Versus Unstable Patterns of Subjective Cognitive Decline
Wolfsgruber, S., for the AgeCoDe Study Group, Kleineidam, L., Wagner, M., Mösch, E., Bickel, H., Lϋhmann, D., Ernst, A., Wiese, B., Steinmann, S., et al. (2016) · Journal of Alzheimer's Disease · doi:10.3233/jad-160407 · Cited by 94 · see citing works
White matter hyperintensities are more highly associated with preclinical Alzheimer's disease than imaging and cognitive markers of neurodegeneration
Kandel, B. M., Avants, B., Gee, J. C., McMillan, C. T., Erus, G., Doshi, J. J., Davatzikos, C. A., Wolk, D. A., & Initiative, A. D. N. (2016) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1016/j.dadm.2016.03.001 · Cited by 94 · see citing works
Using Neuropsychological Process Scores to Identify Subtle Cognitive Decline and Predict Progression to Mild Cognitive Impairment
Thomas, K. R., Edmonds, E. C., Eppig, J. S., Salmon, D. P., Bondi, M. W., & Initiative, A. D. N. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180229 · Cited by 93 · see citing works
Self-citation
“Missed” Mild Cognitive Impairment: High False-Negative Error Rate Based on Conventional Diagnostic Criteria
Edmonds, E. C., Initiative, A. D. N., Delano‐Wood, L., Jak, A. J., Galasko, D. R., Salmon, D. P., & Bondi, M. W. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-150986 · Cited by 91 · see citing works
Self-citation
Increasing Inaccuracy of Self-Reported Subjective Cognitive Complaints Over 24 Months in Empirically Derived Subtypes of Mild Cognitive Impairment
Edmonds, E. C., Weigand, A. J., Thomas, K. R., Eppig, J. S., Delano‐Wood, L., Galasko, D. R., Salmon, D. P., & Bondi, M. W. (2018) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617718000486 · Cited by 89 · see citing works
Self-citation
Evolution of anosognosia in alzheimer's disease and its relationship to amyloid
Hanseeuw, B. J., Scott, M. R., Sikkes, S. A. M., Properzi, M. J., Gatchel, J. R., Salmon, É., Marshall, G. A., Vannini, P., & Initiative, A. D. N. (2019) · Annals of Neurology · doi:10.1002/ana.25649 · Cited by 81 · see citing works
Importance of Treatment Status in Links Between Type 2 Diabetes and Alzheimer’s Disease
McIntosh, E. C., Nation, D. A., & Initiative, A. D. N. (2019) · Diabetes Care · doi:10.2337/dc18-1399 · Cited by 77 · see citing works
Subjective cognitive decline: Memory complaints, cognitive awareness, and metacognition
Cappa, S. F., Ribaldi, F., Chicherio, C., & Frisoni, G. B. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.13905 · Cited by 74 · see citing works
Everyday functioning and cognitive correlates in healthy older adults with subjective cognitive concerns
McAlister, C. B., & Schmitter‐Edgecombe, M. (2016) · The Clinical Neuropsychologist · doi:10.1080/13854046.2016.1190404 · Cited by 73 · see citing works
Prognosis of Early-Onset vs. Late-Onset Mild Cognitive Impairment: Comparison of Conversion Rates and Its Predictors
Tábuas‐Pereira, M., Baldeiras, I., Duro, D., Santiago, B., Ribeiro, M. J., Leitão, M. J., Oliveira, C. R., & Santana, I. J. (2016) · Geriatrics · doi:10.3390/geriatrics1020011 · Cited by 69 · see citing works
Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?
Zwart, W. T., Terra, H., Linn, S. C., & Schagen, S. B. (2015) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2015.124 · Cited by 67 · see citing works
Informant Reporting in Mild Cognitive Impairment: Sources of Discrepancy on the Functional Activities Questionnaire
Hackett, K., Mis, R. E., Drabick, D. A. G., & Giovannetti, T. (2020) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617719001449 · Cited by 65 · see citing works
MCI‐to‐normal reversion using neuropsychological criteria in the Alzheimer's Disease Neuroimaging Initiative
Thomas, K. R., Edmonds, E. C., Eppig, J. S., Wong, C. G., Weigand, A. J., Bangen, K. J., Jak, A. J., Delano‐Wood, L., Galasko, D. R., Salmon, D. P., et al. (2019) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2019.06.4948 · Cited by 65 · see citing works
Self-citation
Awareness of Cognitive Decline in Patients With Alzheimer's Disease: A Systematic Review and Meta-Analysis
Cacciamani, F., Houot, M., Gagliardi, G. P., Dubois, B., Sikkes, S. A. M., Sánchez‐Benavides, G., Denicolò, E., Molinuevo, J. L., Vannini, P., & Epelbaum, S. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.697234 · Cited by 63 · see citing works
Subjective Cognitive Impairment Is a Predominantly Benign Condition in Memory Clinic Patients Followed for 6 Years: The Gothenburg-Oslo MCI Study
Hessen, E., Eckerström, M., Nordlund, A., Almdahl, I. S., Stålhammar, J., Bjerke, M., Eckerström, C., Göthlin, M., Fladby, T., Reinvang, I., et al. (2017) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000454676 · Cited by 61 · see citing works
Informants’ Perception of Subjective Cognitive Decline Helps to Discriminate Preclinical Alzheimer’s Disease from Normal Aging
Valech, N., Mollica, M. A., Olives, J., Tort‐Merino, A., Fortea, J., Lleó, A., Sánchez‐Saudinós, M. B., Molinuevo, J. L., & Rami, L. (2015) · Journal of Alzheimer s Disease · doi:10.3233/jad-150117 · Cited by 60 · see citing works
Qualitative and quantitative assessment of self‐reported cognitive difficulties in nondemented elders: Association with medical help seeking, cognitive deficits, and β‐amyloid imaging
Joie, R. L., Perrotin, A., Egret, S., Pasquier, F., Tomadesso, C., Mézenge, F., Desgranges, B., Sayette, V. D. L., & Chételat, G. (2016) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1016/j.dadm.2016.12.005 · Cited by 59 · see citing works
The applied implications of age-based stereotype threat for older adults.
Barber, S. J. (2020) · Journal of Applied Research in Memory and Cognition · doi:10.1016/j.jarmac.2020.05.002 · Cited by 56 · see citing works
Biomarkers in subtypes of mild cognitive impairment and subjective cognitive decline
Eliassen, C. F., Reinvang, I., Selnes, P., Grambaitė, R., Fladby, T., & Hessen, E. (2017) · Brain and Behavior · doi:10.1002/brb3.776 · Cited by 50 · see citing works
Face-Name Associative Recognition Deficits in Subjective Cognitive Decline and Mild Cognitive Impairment
Polcher, A. A., Frommann, I., Koppara, A., Wolfsgruber, S., Jessen, F., & Wagner, M. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-160637 · Cited by 49 · see citing works
Accuracy of Patient and Care Partner Identification of Cognitive Impairments in Parkinson's Disease–Mild Cognitive Impairment
Copeland, J. N., LIEBERMAN, A. N., Oravivattanakul, S., & Tröster, A. I. (2016) · Movement Disorders · doi:10.1002/mds.26619 · Cited by 48 · see citing works
Subjective Cognitive Complaints in Parkinson's Disease: A Systematic Review and Meta‐Analysis
Siciliano, M., Tessitore, A., Morgante, F., Goldman, J. G., & Ricciardi, L. (2024) · Movement Disorders · doi:10.1002/mds.29649 · Cited by 44 · see citing works
Understanding machine learning applications in dementia research and clinical practice: a review for biomedical scientists and clinicians
Wang, Y., Liu, S., Spiteri, A. G., Huynh, A. L. H., Chu, C., Masters, C. L., Goudey, B., Pan, Y., & Jin, L. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01540-6 · Cited by 48 · see citing works
Mild Cognitive Impairment Reversion and Progression: Rates and Predictors in Community-Living Older Persons in the Singapore Longitudinal Ageing Studies Cohort
Gao, Q., Gwee, X., Feng, L., Nyunt, M. S. Z., Feng, L., Collinson, S. L., Chong, M. S., Lim, W. S., Lee, T.-S. W., Yap, P. L. K., et al. (2018) · Dementia and Geriatric Cognitive Disorders Extra · doi:10.1159/000488936 · Cited by 45 · see citing works
The Virtual Kitchen Challenge: preliminary data from a novel virtual reality test of mild difficulties in everyday functioning
Giovannetti, T., Yamaguchi, T., Roll, E. E., Harada, T., Rycroft, S. S., Divers, R. M., Hulswit, J., Tan, C. C., Matchanova, A., Ham, L., et al. (2018) · Aging Neuropsychology and Cognition · doi:10.1080/13825585.2018.1536774 · Cited by 45 · see citing works
Data-Driven vs Consensus Diagnosis of MCI
Edmonds, E. C., Smirnov, D. S., Thomas, K. R., Graves, L. V., Bangen, K. J., Delano‐Wood, L., Galasko, D. R., Salmon, D. P., & Bondi, M. W. (2021) · Neurology · doi:10.1212/wnl.0000000000012600 · Cited by 44 · see citing works
Self-citation
Trajectory of Unawareness of Memory Decline in Individuals With Autosomal Dominant Alzheimer Disease
Vannini, P., Hanseeuw, B. J., Gatchel, J. R., Sikkes, S. A. M., Alzate, D., Zuluaga, Y., Moreno, S., Méndez, L., Baena, A. Y., Ospina-Lopera, P., et al. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.27472 · Cited by 44 · see citing works
Gray matter structural covariance networks changes along the Alzheimer's disease continuum
Li, K., Luo, X., Zeng, Q., Huang, P., Shen, Z., Xu, X., Xu, J., Wang, C., Zhou, J., & Zhang, M. (2019) · NeuroImage Clinical · doi:10.1016/j.nicl.2019.101828 · Cited by 42 · see citing works
Self‐ and informant‐reported cognitive functioning and awareness in subjective cognitive decline, mild cognitive impairment, and very mild Alzheimer disease
Ryu, S. Y., Kim, A., Kim, S., Park, K. W., Park, K. H., Youn, Y. C., Lee, D. W., Lee, J., Lee, J. H., Jeong, J. H., et al. (2019) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5224 · Cited by 42 · see citing works
Body Temperature Is Associated With Cognitive Performance in Older Adults With and Without Mild Cognitive Impairment: A Cross-sectional Analysis
Eggenberger, P., Bürgisser, M., Rossi, R. M., & Annaheim, S. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.585904 · Cited by 42 · see citing works
Responsible development of clinical speech AI: Bridging the gap between clinical research and technology
Berisha, V., & Liss, J. M. (2024) · npj Digital Medicine · doi:10.1038/s41746-024-01199-1 · Cited by 41 · see citing works
Comparing the relationship between subjective memory complaints, objective memory performance, and medial temporal lobe volumes in patients with mild cognitive impairment
Fyock, C., & Hampstead, B. M. (2015) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1016/j.dadm.2015.03.002 · Cited by 40 · see citing works
Prognostic Significance of Mild Cognitive Impairment Subtypes for Dementia and Mortality: Data from the NEDICES Cohort
Bermejo‐Pareja, F., Contador, I., Trincado, R., Lora, D., Sánchez‐Ferro, Á., Mitchell, A. J., Boycheva, E., Herrero, A., Hernández‐Gallego, J., Velasco, S. L., et al. (2016) · Journal of Alzheimer s Disease · doi:10.3233/jad-150625 · Cited by 40 · see citing works
Quality of self-reported cognition: effects of age and gender on spatial navigation self-reports
van der Ham, I. J. M., van der Kuil, M. N. A., & Claessen, M. H. G. (2020) · Aging & Mental Health · doi:10.1080/13607863.2020.1742658 · Cited by 40 · see citing works
Examining the Role of the Noradrenergic Locus Coeruleus for Predicting Attention and Brain Maintenance in Healthy Old Age and Disease: An MRI Structural Study for the Alzheimer’s Disease Neuroimaging Initiative
Plini, E. R. G., O’Hanlon, E., Boyle, R. T., Sibilia, F., Rikhye, G., Kenney, J. P. M., Whelan, R., Melnychuk, M. C., Robertson, I. H., & Dockree, P. M. (2021) · Cells · doi:10.3390/cells10071829 · Cited by 39 · see citing works
Self and informant memory concerns align in healthy memory complainers and in early stages of mild cognitive impairment but separate with increasing cognitive impairment
Buckley, R. F., Saling, M. M., Ellis, K. A., Rowe, C., Maruff, P. T., Macaulay, L. S., Martins, R. N., Masters, C. L., Savage, G. R., Rainey‐Smith, S. R., et al. (2015) · Age and Ageing · doi:10.1093/ageing/afv136 · Cited by 38 · see citing works
Do informant-reported subjective cognitive complaints predict progression to mild cognitive impairment and dementia better than self-reported complaints in old adults? A meta-analytical study
Pérez‐Blanco, L., Felpete, A., Patten, S. B., Mallo, S. C., Pereiro, A. X., Campos‐Magdaleno, M., & Juncos‐Rabadán, O. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101772 · Cited by 37 · see citing works
Neuropsychological Criteria for Mild Cognitive Impairment in the Framingham Heart Study’s Old-Old
Wong, C. G., Thomas, K. R., Edmonds, E. C., Weigand, A. J., Bangen, K. J., Eppig, J. S., Jak, A. J., Devine, S., Delano‐Wood, L., Libon, D. J., et al. (2018) · Dementia and Geriatric Cognitive Disorders · doi:10.1159/000493541 · Cited by 37 · see citing works
Self-citation
Memory concerns in the early Alzheimer's disease prodrome: Regional association with tau deposition
Swinford, C. G., Risacher, S. L., Charil, A., Schwarz, A. J., Saykin, A. J., & Initiative, A. D. N. (2018) · Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring · doi:10.1016/j.dadm.2018.03.001 · Cited by 36 · see citing works
Subjective cognitive decline and objective cognition among diverse U.S. Hispanics/Latinos: Results from the Study of Latinos‐Investigation of Neurocognitive Aging (SOL‐INCA)
Zlatar, Z. Z., Tarraf, W., González, K. A., Vásquez, P. M., Marquine, M. J., Lipton, R. B., Gallo, L. C., Khambaty, T., Zeng, D., Youngblood, M., et al. (2021) · Alzheimer s & Dementia · doi:10.1002/alz.12381 · Cited by 34 · see citing works
The role of dyadic cognitive report and subjective cognitive decline in early ADRD clinical research and trials: Current knowledge, gaps, and recommendations
Nosheny, R. L., Amariglio, R. E., Sikkes, S. A. M., Hulle, C. V., Bicalho, M. A. C., Dowling, N. M., Brucki, S. M. D., Ismail, Z., Kasuga, K., Kuhn, E., et al. (2022) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1002/trc2.12357 · Cited by 36 · see citing works
Artificially low mild cognitive impairment to normal reversion rate in the Alzheimer's Disease Neuroimaging Initiative
Thomas, K. R., Eppig, J. S., Weigand, A. J., Edmonds, E. C., Wong, C. G., Jak, A. J., Delano‐Wood, L., Galasko, D. R., Salmon, D. P., Edland, S. D., et al. (2019) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2018.10.008 · Cited by 35 · see citing works
Self-citation
Sex Influences the Accuracy of Subjective Memory Complaint Reporting in Older Adults
Sundermann, E. E., Edmonds, E. C., Delano‐Wood, L., Galasko, D. R., Salmon, D. P., Rubin, L. H., Bondi, M. W., & Initiative, A. D. N. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-170425 · Cited by 34 · see citing works
Self-citation
A Link between Subjective Perceptions of Memory and Physical Function: Implications for Subjective Cognitive Decline
Cosentino, S., Devanand, D. P., & Gurland, B. J. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-170495 · Cited by 34 · see citing works
Cognitive impairment no dementia and associations with health literacy, self-management skills, and functional health status
Lovett, R., Curtis, L. M., Persell, S. D., Griffith, J. W., Cobia, D. J., Federman, A. D., & Wolf, M. S. (2020) · Patient Education and Counseling · doi:10.1016/j.pec.2020.03.013 · Cited by 34 · see citing works
A Conceptual Framework for Research on Cognitive Impairment with no Dementia in Memory Clinic
Huang, L., Chen, K., Liu, Z., & Guo, Q. (2020) · Current Alzheimer Research · doi:10.2174/1567205017666200807193253 · Cited by 34 · see citing works
Subjective cognitive complaints versus objective neuropsychological performance in older adults with epilepsy
Galioto, R., Blum, A. S., & Tremont, G. N. (2015) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2015.06.035 · Cited by 31 · see citing works
Official position of the American Academy of Clinical Neuropsychology on test security
Boone, K. B., Sweet, J. J., Byrd, D., Denney, R. L., Hanks, R. A., Kaufmann, P. M., Kirkwood, M. W., Larrabee, G. J., Marcopulos, B. A., Morgan, J. E., et al. (2022) · The Clinical Neuropsychologist · doi:10.1080/13854046.2021.2022214 · Cited by 29 · see citing works
Self- and Informant-Reported Memory Complaints: Frequency and Severity in Cognitively Intact Individuals and those with Mild Cognitive Impairment and Neurodegenerative Dementias
Rahman‐Filipiak, A., Giordani, B., Heidebrink, J. L., Bhaumik, A., & Hampstead, B. M. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180083 · Cited by 26 · see citing works
Neuropsychological Decline Improves Prediction of Dementia Beyond Alzheimer’s Disease Biomarker and Mild Cognitive Impairment Diagnoses
Nation, D. A., Ho, J. K., Dutt, S., Han, S. D., Lai, M. H. C., & Initiative, A. D. N. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-180525 · Cited by 26 · see citing works
Systematic Review of the Psychometric Properties of the Saint Louis University Mental Status (SLUMS) Examination
Spencer, R. J., Noyes, E. T., Bair, J. L., & Ransom, M. T. (2022) · Clinical Gerontologist · doi:10.1080/07317115.2022.2032523 · Cited by 26 · see citing works
Subjective Memory Complaints in White and African American Participants
John, S. E., Evans, S. A., Hanfelt, J., Loring, D. W., & Goldstein, F. C. (2019) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988719868305 · Cited by 24 · see citing works
Cognitive and anatomical correlates of anosognosia in amnestic mild cognitive impairment and early-stage Alzheimer's disease
Senturk, G., Bılgıç, B., Arslan, A. B., Bayram, A., Hanagasi, H. A., Gurvit, H. I., & Emre, M. (2016) · International Psychogeriatrics · doi:10.1017/s1041610216001812 · Cited by 23 · see citing works
Staging the cognitive continuum in prodromal Alzheimer's disease with episodic memory
Moscoso, A., Silva‐Rodríguez, J., Aldrey, J. M., Cortés, J., Fernández‐Ferreiro, A., Gómez‐Lado, N., Ruibal, Á., & Aguiar, P. (2019) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2019.07.014 · Cited by 23 · see citing works
Domains of Functional Impairment and Their Associations with Thwarted Belonging and Perceived Burden in Older Adults
Mournet, A. M., Bower, E. S., & Orden, K. A. V. (2019) · Clinical Gerontologist · doi:10.1080/07317115.2019.1650406 · Cited by 24 · see citing works
Investigating the association between subjective and objective performance-based cognitive function among former collegiate football players
Bryant, A. M., Kerr, Z. Y., Walton, S. R., Barr, W., Guskiewicz, K. M., McCrea, M., & Brett, B. L. (2022) · The Clinical Neuropsychologist · doi:10.1080/13854046.2022.2083021 · Cited by 24 · see citing works
Word Recall: Cognitive Performance Within Internet Surveys
Runge, S. K., Craig, B. M., & Jim, H. (2015) · JMIR Mental Health · doi:10.2196/mental.3969 · Cited by 23 · see citing works
Everyday cognition scales are related to cognitive function in the early stage of probable Alzheimer’s disease and FDG-PET findings
Hsu, J., Hsu, W., Chang, C.-C., Lin, K., Hsiao, I., Fan, Y., & Bai, C. (2017) · Scientific Reports · doi:10.1038/s41598-017-01193-6 · Cited by 23 · see citing works
Population Health Solutions for Assessing Cognitive Impairment in Geriatric Patients
Perry, W., Lacritz, L., Roebuck‐Spencer, T., Silver, C. H., Denney, R. L., Meyers, J. E., McConnel, C. E., Pliskin, N. H., Adler, D., Alban, C., et al. (2018) · Innovation in Aging · doi:10.1093/geroni/igy025 · Cited by 24 · see citing works
Self-citation
Neuroanatomical and Neuropsychological Markers of Amnestic MCI: A Three-Year Longitudinal Study in Individuals Unaware of Cognitive Decline
Goerlich, K. S., Votinov, M., Dicks, E., Ellendt, S., Csukly, G., & Habel, U. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00034 · Cited by 23 · see citing works
Subjective cognitive and non‐cognitive complaints and brain MRI biomarkers in the MEMENTO cohort
Dauphinot, V., Bouteloup, V., Mangin, J., Vellas, B. J., Pasquier, F., Blanc, F., Hanon, O., Gabelle, A., Annweiler, C., David, R., et al. (2020) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12051 · Cited by 20 · see citing works
Complainer Profile Identification (CPI): properties of a new questionnaire on subjective cognitive complaints
Lubitz, A. F., Eid, M., & Niedeggen, M. (2016) · Aging Neuropsychology and Cognition · doi:10.1080/13825585.2016.1267325 · Cited by 22 · see citing works
Impaired cognition in narcolepsy: clinical and neurobiological perspectives
Cano, C. A., Harel, B. T., & Scammell, T. E. (2024) · SLEEP · doi:10.1093/sleep/zsae150 · Cited by 22 · see citing works
Decreased Self-Appraisal Accuracy on Cognitive Tests of Executive Functioning Is a Predictor of Decline in Mild Cognitive Impairment
Scherling, C., Wilkins, S., Zakrezewski, J., Kramer, J. H., Miller, B. L., Weiner, M. W., & Rosen, H. J. (2016) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2016.00120 · Cited by 21 · see citing works
Screening of visual perceptual disorders following acquired brain injury: A Delphi study
de Vries, S. M., Heutink, J., Melis-Dankers, B., Vrijling, A. C. L., Cornelissen, F. W., & Tucha, O. M. (2017) · Applied Neuropsychology Adult · doi:10.1080/23279095.2016.1275636 · Cited by 21 · see citing works
Foreign Language Learning as Cognitive Training to Prevent Old Age Disorders? Protocol of a Randomized Controlled Trial of Language Training vs. Musical Training and Social Interaction in Elderly With Subjective Cognitive Decline
Nijmeijer, S. E., van Tol, M., Aleman, A., & Keijzer, M. C. J. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.550180 · Cited by 20 · see citing works
Beyond depression: examining the role of anxiety and anxiety sensitivity on subjective cognition and functioning in older adults
Divers, R. M., Robinson, A. D., Miller, L. R., Vito, A. N. D., Pugh, E., & Calamia, M. R. (2021) · Aging & Mental Health · doi:10.1080/13607863.2021.1966747 · Cited by 20 · see citing works
Mood and Personality Characteristics are Associated with Metamemory Knowledge Accuracy in a Community-Based Cohort of Older Adults
Colvin, L. E., Malgaroli, M., Chapman, S., MacKay‐Brandt, A., & Cosentino, S. (2018) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617717001345 · Cited by 20 · see citing works
Mild cognitive impairment and neuropsychological examination
Hessen, E. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1662151 · Cited by 19 · see citing works
Neurocognitive deficits in COVID-19 patients five months after discharge from hospital
Thornberg, U. B., Andersson, A., Lindh, M., Hellgren, L., Divanoglou, A., & Levi, R. (2022) · Neuropsychological Rehabilitation · doi:10.1080/09602011.2022.2125020 · Cited by 19 · see citing works
Population Health Solutions for Assessing Cognitive Impairment in Geriatric Patients
Perry, W., Lacritz, L., Roebuck‐Spencer, T., Silver, C. H., Denney, R. L., Meyers, J. E., McConnel, C. E., Pliskin, N. H., Adler, D., Alban, C., et al. (2018) · The Clinical Neuropsychologist · doi:10.1080/13854046.2018.1517503 · Cited by 19 · see citing works
Self-citation
Memory impairment and Alzheimer's disease pathology in individuals with MCI who underestimate or overestimate their decline
Bregman, N., Kavé, G., Zeltzer, E., Biran, I., & Initiative, A. D. N. (2020) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5274 · Cited by 18 · see citing works
Evidence for the Utility of Actuarial Neuropsychological Criteria Across the Continuum of Normal Aging, Mild Cognitive Impairment, and Dementia
Graves, L. V., Edmonds, E. C., Thomas, K. R., Weigand, A. J., Cooper, S., & Bondi, M. W. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200778 · Cited by 19 · see citing works
Self-citation
Self-reported subjective cognitive decline is associated with global cognition in a community sample of Latinos/as/x living in the United States
Nakhla, M. Z., Cohen, L., Salmon, D. P., Smirnov, D. S., Marquine, M. J., Moore, A. A., Schiehser, D. M., & Zlatar, Z. Z. (2021) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/13803395.2021.1989381 · Cited by 21 · see citing works
Self-citation
The Cognitive Difficulties Scale (CDS): Psychometric Characteristics in a Clinical Referral Sample
Gass, C. S., Patten, B., Peñate, A., & Rhodes, A. (2020) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617720001058 · Cited by 18 · see citing works
Long COVID neuropsychological follow-up: Is cognitive rehabilitation relevant?
Braga, L. W., de Oliveira, S. B., Moreira, A. S., Pereira, M. E. M. D. S. M., Serio, A., Carneiro, V. D. S., Freitas, L. D. F. P., & Souza, L. M. D. N. (2023) · Neurorehabilitation · doi:10.3233/nre-230212 · Cited by 20 · see citing works
Diagnosing Mild Cognitive Impairment as a Precursor to Dementia: Fact or Fallacy?
Klekociuk, S. Z., Saunders, N. L., & Summers, M. J. (2016) · Australian Psychologist · doi:10.1111/ap.12178 · Cited by 18 · see citing works
Alzheimer’s disease risk factors as mediators of subjective memory impairment and objective memory decline: protocol for a construct-level replication analysis
Hill, N. L., & Mogle, J. A. (2018) · BMC Geriatrics · doi:10.1186/s12877-018-0954-5 · Cited by 18 · see citing works
Evaluating PROMIS Physical Function Measures in Older Adults at Risk for Alzheimer’s Disease
Tatsuoka, C. M., DeMarco, L., Smyth, K. A., Wilkes, S., Howland, M., Lerner, A. J., & Sajatovic, M. (2016) · Gerontology and Geriatric Medicine · doi:10.1177/2333721416665502 · Cited by 17 · see citing works
MEG Oscillatory Slowing in Cognitive Impairment is Associated with the Presence of Subjective Cognitive Decline
Bruña, R., López‐Sanz, D., Maestú, F., Cohen, A. D., Bagic, A. I., Huppert, T., Kim, T., Roush, R. E., Snitz, B., & Becker, J. T. (2022) · Clinical EEG and Neuroscience · doi:10.1177/15500594221072708 · Cited by 17 · see citing works
Effects of personal dementia exposure on subjective memory concerns and dementia worry
Lee, G. J., Do, C., & Suhr, J. A. (2020) · Aging Neuropsychology and Cognition · doi:10.1080/13825585.2020.1836119 · Cited by 17 · see citing works
Executive Function Predicts the Validity of Subjective Memory Complaints in Older Adults beyond Demographic, Emotional, and Clinical Factors
Chao, R.-Y., Chen, T., & Chang, Y. (2021) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2020.61 · Cited by 17 · see citing works
Examining racial disparities in the diagnosis of mild cognitive impairment
Kiselica, A. M., Johnson, E. E. H., Lewis, K. R., & Trout, K. E. (2021) · Applied Neuropsychology Adult · doi:10.1080/23279095.2021.1976778 · Cited by 17 · see citing works
Brain Functional Alterations and Association with Cognition in People with Preclinical Subjective Cognitive Decline and Objective Subtle Cognitive Difficulties
Ren, S., Li, J., Huang, L., Huang, Q., Chen, K., Hu, J., Jessen, F., Hu, X., Jiang, D., Zhu, L., et al. (2023) · Neuroscience · doi:10.1016/j.neuroscience.2023.01.004 · Cited by 17 · see citing works
The frequency of self-reported memory failures is influenced by everyday context across the lifespan: Implications for neuropsychology research and clinical practice
Tassoni, M. B., Drabick, D. A. G., & Giovannetti, T. (2022) · The Clinical Neuropsychologist · doi:10.1080/13854046.2022.2112297 · Cited by 16 · see citing works
Subjective Cognitive Complaints: Comparing the Relation between Self-Reported Versus Informant-Reported Subjective Cognitive Complaints and Cognitive Performances in Cognitively Unimpaired, Mild Cognitive Impairment and Populations with Dementia
Peng, S.-W., Wang, C.-Y., Lin, S.-Y., Lee, Y.-L., Lin, Y.-C., Lin, Y.-J., & Wang, P.-N. (2023) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2023.47 · Cited by 16 · see citing works

P1‐340: SUBJECTIVE COGNITIVE COMPLAINTS CONTRIBUTE TO MISDIAGNOSIS OF MILD COGNITIVE IMPAIRMENT
Edmonds, E. C., Delano‐Wood, L., Galasko, D. R., Salmon, D. P., & Bondi, M. W. (2014) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2014.05.581 · Cited by 1 · see citing works
Self-citation
Increasing Inaccuracy of Self-Reported Subjective Cognitive Complaints Over 24 Months in Empirically Derived Subtypes of Mild Cognitive Impairment
Edmonds, E. C., Weigand, A. J., Thomas, K. R., Eppig, J. S., Delano‐Wood, L., Galasko, D. R., Salmon, D. P., & Bondi, M. W. (2018) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617718000486 · Cited by 89 · see citing works
Self-citation
Absence of a relationship between subjective memory complaint and objective memory impairment in mild cognitive impairment (MCI): is it time to abandon subjective memory complaint as an MCI diagnostic criterion?
Lenehan, M. E., Klekociuk, S. Z., & Summers, M. J. (2012) · International Psychogeriatrics · doi:10.1017/s1041610212000695 · Cited by 119 · see citing works
P3‐117: Subjective complaint and cognitive aging
Tripodis, Y., Palmisano, J. N., Gentile, A. M., & Jefferson, A. L. (2011) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2011.05.1557
P4‐468: Subjective complaint and cognitive aging
Tripodis, Y., Palmisano, J. N., Gentile, A. M., & Jefferson, A. L. (2011) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2011.09.161

Authors: Edmonds, E. C., Delano-Wood, L., Galasko, D. R., Salmon, D. P., & Bondi, M. W.
Affiliations: University of California San Diego (US)
Corresponding author: Bondi, Mark W.
ORCID: Edmonds, Emily C.
Galasko, Douglas R.
Salmon, David P.
Bondi, Mark W.
Venue: Journal of the International Neuropsychological Society
Publisher: Cambridge University Press (CUP)
Published: 2014-08-22
Volume: 20
Issue: 8
Pages: 836-847
ISSN: 1355-6177 (ISSN-L)
1469-7661
DOI: 10.1017/s135561771400068x
PMC: PMC4172502
OpenAlex: W2077841286
Cited by: 249
References: 45
Citations by year: 2026: 17 · 2025: 21 · 2024: 28 · 2023: 21 · 2022: 18 · 2021: 27 · 2020: 21 · 2019: 22 · 2018: 20 · 2017: 16 · 2016: 25 · 2015: 13
FWCI: 13.74
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.cambridge.org/core/terms (unspecified)
Locations: Journal of the International Neuropsychological Society (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
eScholarship (California Digital Library) (submittedVersion)
Funders: U.S. Department of Defense (U01 AG024904, AG024904)
Alzheimer's Association (U01 AG024904, W81XWH-12-2-0012)
Bristol-Myers Squibb (U01 AG024904, AG024904, W81XWH-12-2-0012)
Eli Lilly and Company (U01 AG024904, AG024904, W81XWH-12-2-0012)
Pfizer (AG024904, W81XWH-12-2-0012, U01 AG024904)
Biogen (W81XWH-12-2-0012, U01 AG024904, AG024904)
University of Southern California (W81XWH-12-2-0012, U01 AG024904)
CHDI Foundation
F. Hoffmann-La Roche (W81XWH-12-2-0012, AG024904, U01 AG024904)
Medpace (U01 AG024904)
Meso Scale Diagnostics (U01 AG024904, AG024904, W81XWH-12-2-0012)
Synarc (U01 AG024904)
Alzheimer's Disease Neuroimaging Initiative (W81XWH-12-2–0012, U01AG024904, AG024904, W81XWH-12-2-)
BioClinica (U01 AG024904, W81XWH-12-2-0012, AG024904)
Novartis Pharmaceuticals Corporation (W81XWH-12-2-0012, U01 AG024904, AG024904)
Northern California Institute for Research and Education (U01 AG024904, W81XWH-12-2-0012)
Eisai (W81XWH-12-2-0012, U01 AG024904, AG024904)
Servier (AG024904, W81XWH-12-2-0012, U01 AG024904)
IXICO (AG024904, W81XWH-12-2-0012, U01 AG024904)
National Institutes of Health (5u01ag024904-10, W81XWH-12-2-0012, U01-AG024904, AG024904, AG05131)
Genentech (W81XWH-12-2-0012, AG024904, U01 AG024904)
University of California, San Diego
Canadian Institutes of Health Research (U01 AG024904, W81XWH-12-2-0012)
National Institute on Aging (U01-AG-024904, P50AG005131, R01AG012674, P30AG013846, U19AG010483, K24AG026431, U19AG024904, U24AG021886, P50-AG05131)
National Institute of Mental Health (T32MH018399)
National Institute of Biomedical Imaging and Bioengineering (P41EB015922)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Cancer-related cognitive impairment studies
Social Sciences › Psychology › Experimental and Cognitive Psychology › Cognitive Functions and Memory
Keywords: subjective cognitive complaints, mild cognitive impairment, misdiagnosis, self-report versus informant report, amnestic MCI, cognitive decline, depressive symptoms, normal aging, dementia progression, ADNI
MeSH terms: Aged, Aged, 80 and over, Analysis of Variance, Attention, Diagnostic Errors, Female, Humans, Language, Male, Middle Aged, Neuropsychological Tests, Peptide Fragments, Surveys and Questionnaires, Discriminant Analysis, Amyloid beta-Peptides, tau Proteins, Self Report, Cognitive Dysfunction

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Subjective Cognitive Complaints Contribute to Misdiagnosis of Mild Cognitive Impairment

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks