Cited by 369biodegradable polymer synthesis and propertiesBone Tissue Engineering Materials3D Printing in Biomedical Research

Fabrication of Biomedical Scaffolds Using Biodegradable Polymers.

Kirillova, Alina, Yeazel, Taylor R., Asheghali, Darya, Petersen, Shannon R., Dort, Sophia, Gall, Ken, Becker, Matthew L.·2021·Chemical Reviews

Abstract

Degradable polymers are used widely in tissue engineering and regenerative medicine. Maturing capabilities in additive manufacturing coupled with advances in orthogonal chemical functionalization methodologies have enabled a rapid evolution of defect-specific form factors and strategies for designing and creating bioactive scaffolds. However, these defect-specific scaffolds, especially when utilizing degradable polymers as the base material, present processing challenges that are distinct and unique from other classes of materials. The goal of this review is to provide a guide for the fabrication of biodegradable polymer-based scaffolds that includes the complete pathway starting from selecting materials, choosing the correct fabrication method, and considering the requirements for tissue specific applications of the scaffold.

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Crossref · 10.1021/acs.chemrev.0c01200

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Cites

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4 of the 459 references couldn’t be matched to a known paper.

Research works printed but not linked: 9

  1. Hart N. H., 2017, J. Musculoskelet. Neuronal Interact., 17, 114
  2. 10.1016/j.actbio.2019.07.045 · DOI
  3. 10.1021/acs.biomac.9b01126 · DOI
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Authors
Kirillova, A., Yeazel, T. R., Asheghali, D., Petersen, S. R., Dort, S., Gall, K., & Becker, M. L.
Affiliations
Duke University (US)
Corresponding author
Becker, Matthew L.
Venue
Chemical Reviews
Published
2021-04-15
Volume
121
Issue
18
Pages
11238-11304
ISSN
  • 0009-2665 (ISSN-L)
  • 1520-6890
OpenAlex
W3155020406
Cited by
368
References
459
Citations by year
2026: 66 · 2025: 96 · 2024: 95 · 2023: 57 · 2022: 44 · 2021: 10
FWCI
3.57
Type
journal article
Language
en
Open access
closed
Locations
  • Chemical Reviews (publishedVersion)
  • PubMed (publishedVersion)
Funders
Division of Materials Research (1507420)
Topics
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
  • Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
  • Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
Keywords
biodegradable polymers, biomedical scaffolds, scaffold fabrication, tissue engineering, additive manufacturing, chemical functionalization, regenerative medicine, scaffold design
MeSH terms
Biocompatible Materials, Polymers, Tissue Engineering, Regenerative Medicine, Tissue Scaffolds

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