Anxiety sensitivity and the anxiety disorders: A meta-analytic review and synthesis.

Olatunji, Bunmi O.; Wolitzky-Taylor, Kate B.

doi:10.1037/a0017428

Cited by 609Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychosomatic Disorders and Their TreatmentsChild and Adolescent Psychosocial and Emotional Development

Anxiety sensitivity and the anxiety disorders: A meta-analytic review and synthesis.

Olatunji, Bunmi O., Wolitzky-Taylor, Kate B.·2009·Psychological Bulletin

DOI 10.1037/a0017428

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Abstract

There has been significant interest in the role of anxiety sensitivity (AS) in the anxiety disorders. In this meta-analysis, we empirically evaluate differences in AS between anxiety disorders, mood disorders, and nonclinical controls. A total of 38 published studies (N = 20,146) were included in the analysis. The results yielded a large effect size indicating greater AS among anxiety disorder patients versus nonclinical controls (d = 1.61). However, this effect was maintained only for panic disorder patients compared to mood disorder patients (d = 0.85). Panic disorder was also associated with greater AS compared to other anxiety disorders except for posttraumatic stress disorder (d = 0.04). Otherwise the anxiety disorders generally did not differ from each other in AS. Although these findings suggest that AS is central to the phenomenology of panic disorder and posttraumatic stress disorder, causal inferences regarding the role of AS in these anxiety disorders cannot be made. Moderator analyses showed that a greater proportion of female participants was associated with larger differences in AS between anxiety and nonclinical control groups. However, more female participants were associated with a smaller AS difference between anxiety and mood disorder groups. This finding suggests that AS is less robust in distinguishing anxiety from mood disorders among women. Age also moderated some observed effects such that AS was more strongly associated with anxiety disorders in adults compared to children. Type of AS measure used also moderated some effects. Implications of these findings for the conceptualization of AS in anxiety-related disorders are discussed.

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Further cognitive constructs related to health anxiety include higher levels of anxiety sensitivity, health-related rumination, and health-related intolerance of uncertainty.
“Further cognitive constructs related to health anxiety include higher levels of anxiety sensitivity, the fear of arousal-related bodily sensations [50, 51], health-related rumination [52], and health-related intolerance of uncertainty which is essentially a reduced capacity to endure the perception of missing important information [53–55].”
From Illness Anxiety Disorder: A Review of the Current Research and Future Directions (2024) · cites this paper as [51]

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Panic disorder and bipolar disorder: Anxiety sensitivity as a potential mediator of panic during manic states
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Confirmatory Factor Analysis and Psychometric Properties of the Anxiety Sensitivity Index – Revised in Clinical and Normative Populations
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Fear of the unknown: One fear to rule them all?
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Maternal and paternal parenting styles associated with relational aggression in children and adolescents: A conceptual analysis and meta-analytic review
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A systematic review of sleep disturbance in anxiety and related disorders
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An Active Inference Approach to Interoceptive Psychopathology
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Is cyberchondria a new transdiagnostic digital compulsive syndrome? A systematic review of the evidence
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Towards a model of uncertainty distress in the context of Coronavirus (COVID-19)
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Longitudinal treatment mediation of traditional cognitive behavioral therapy and acceptance and commitment therapy for anxiety disorders
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Refinement of a brief anxiety sensitivity reduction intervention.
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Anxiety sensitivity and suicidal ideation/suicide risk: A meta-analysis.
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Randomized Controlled Trial of False Safety Behavior Elimination Therapy: A Unified Cognitive Behavioral Treatment for Anxiety Psychopathology
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Anxiety Sensitivity Index (ASI-3) subscales predict unique variance in anxiety and depressive symptoms
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Emotion and internal experience in Obsessive Compulsive Disorder: Reviewing the role of alexithymia, anxiety sensitivity and distress tolerance
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Evaluating the unique contribution of intolerance of uncertainty relative to other cognitive vulnerability factors in anxiety psychopathology
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The Elicitation of Relaxation and Interoceptive Awareness Using Floatation Therapy in Individuals With High Anxiety Sensitivity
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Reduction of cognitive concerns of anxiety sensitivity is uniquely associated with reduction of PTSD and depressive symptoms: A comparison of civilians and veterans
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Investigating Pristine Inner Experience: Moments of Truth
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Posttraumatic Stress Disorder Symptoms and Suicide Risk in Male Firefighters
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Direct and Mediating Effects of an Anxiety Sensitivity Intervention on Posttraumatic Stress Disorder Symptoms in Trauma-Exposed Individuals
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A Meta-analytic Review of the Role of Child Anxiety Sensitivity in Child Anxiety
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Why Do They Exercise Less? Barriers to Exercise in High-Anxiety-Sensitive Women
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Trait anxiety reduces affective fading for both positive and negative autobiographical memories
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Development and randomized trial evaluation of a novel computer-delivered anxiety sensitivity intervention
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Clarifying the relation of acculturative stress and anxiety/depressive symptoms: The role of anxiety sensitivity among Hispanic college students.
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Anxiety Sensitivity and Intolerance of Uncertainty: Transdiagnostic Risk Factors for Anxiety as Targets to Reduce Risk of Suicide
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A transdiagnostic approach to examining the incremental predictive power of emotion regulation and basic personality dimensions.
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The depression distress amplification model in adolescents: A longitudinal examination of anxiety sensitivity cognitive concerns, depression and suicidal ideation
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Single-Session Anxiety Sensitivity Reduction Program for Trauma-Exposed Adults: A Case Series Documenting Feasibility and Initial Efficacy
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Are childhood trauma exposures predictive of anxiety sensitivity in school attending youth?
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Generalised Anxiety Disorder – A Twin Study of Genetic Architecture, Genome-Wide Association and Differential Gene Expression
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Lower-order anxiety sensitivity and intolerance of uncertainty dimensions operate as specific vulnerabilities for social anxiety and depression within a hierarchical model
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Authors: Olatunji, B. O., & Wolitzky-Taylor, K. B.
Affiliations: Vanderbilt University (US)
University of California, Los Angeles (US)
ORCID: Olatunji, Bunmi O.
Wolitzky-Taylor, Kate B.
Venue: Psychological Bulletin
Publisher: American Psychological Association (APA)
Published: 2009
Volume: 135
Issue: 6
Pages: 974-999
ISSN: 0033-2909 (ISSN-L)
1939-1455
DOI: 10.1037/a0017428
OpenAlex: W1976107439
Cited by: 609
References: 178
Citations by year: 2026: 27 · 2025: 32 · 2024: 27 · 2023: 42 · 2022: 37 · 2021: 39 · 2020: 57 · 2019: 45 · 2018: 50 · 2017: 32 · 2016: 49 · 2015: 48 · 2014: 30 · 2013: 29 · 2012: 32
FWCI: 27.51
Type: journal article
Language: en
Open access: closed
Locations: Psychological Bulletin (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Keywords: anxiety sensitivity, anxiety disorders, panic disorder, post-traumatic stress disorder, mood disorders, sex differences, age differences, phenomenology of anxiety
MeSH terms: Anxiety Disorders, Awareness, Cognition Disorders, Emotions, Humans, Internal-External Control, Personality Assessment, Psychometrics, Psychopathology, Social Perception, Somatoform Disorders, Temperament, Randomized Controlled Trials as Topic, Panic Disorder, Mood Disorders

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Anxiety sensitivity and the anxiety disorders: A meta-analytic review and synthesis.

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