The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Plump, A. S., Smith, J. D., Hayek, T., Aalto-Setälä, K., Walsh, A., Verstuyft, J. G., Rubin, E. M., & Breslow, J. L. (1992) · Cell · doi:10.1016/0092-8674(92)90362-g · Cited by 2,263
Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E
Zhang, S. H., Reddick, R. L., Piedrahita, J. A., & Maeda, N. (1992) · Science · doi:10.1126/science.1411543 · Cited by 2,237
ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.
Nakashima, Y., Plump, A. S., Raines, E. W., Breslow, J. L., & Ross, R. (1994) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.14.1.133 · Cited by 1,693
Schmidt, A. M., Hori, O., Chen, J. X., Li, J. F., Crandall, J., Zhang, J., Cao, R., Yan, S. D., Brett, J., & Stern, D. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118175 · Cited by 896
Self-citationLander, H. M., Tauras, J. M., Ogiste, J. S., Hori, O., Moss, R. A., & Schmidt, A. M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.28.17810 · Cited by 813
Self-citation
Cited by
Biochemistry and molecular cell biology of diabetic complications
Brownlee, M. (2001) · Nature · doi:10.1038/414813a · Cited by 9,107
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
Nishikawa, T., Edelstein, D., Du, X. L., Yamagishi, S.-I., Matsumura, T., Kaneda, Y., Yorek, M. A., Beebe, D., Oates, P. J., Hammes, H.-P., et al. (2000) · Nature · doi:10.1038/35008121 · Cited by 4,277
Mechanisms of Diabetic Complications
Forbes, J. M., & Cooper, M. E. (2013) · Physiological Reviews · doi:10.1152/physrev.00045.2011 · Cited by 2,890
Advanced Glycation End Products: Sparking the Development of Diabetic Vascular Injury
Goldin, A., Beckman, J. A., Schmidt, A. M., & Creager, M. A. (2006) · Circulation · doi:10.1161/circulationaha.106.621854 · Cited by 2,261
Self-citationMechanisms, Pathophysiology, and Therapy of Arterial Stiffness
Zieman, S. J., Melenovsky, V., & Kass, D. A. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000160548.78317.29 · Cited by 1,854
RAGE Mediates a Novel Proinflammatory Axis
Hofmann, M. A., Drury, S., Fu, C., Qu, W., Taguchi, A., Lu, Y., Avila, C., Kambham, N., Bierhaus, A., Nawroth, P., et al. (1999) · Cell · doi:10.1016/s0092-8674(00)80801-6 · Cited by 1,864
Self-citationUnderstanding RAGE, the receptor for advanced glycation end products
Bierhaus, A., Humpert, P. M., Morcos, M., Wendt, T., Chavakis, T., Arnold, B., Stern, D. M., & Nawroth, P. P. (2005) · Journal of Molecular Medicine · doi:10.1007/s00109-005-0688-7 · Cited by 1,297
Self-citationDietary factors and low-grade inflammation in relation to overweight and obesity
Calder, P. C., Ahluwalia, N., Brouns, F., Buetler, T., Clement, K., Cunningham, K., Esposito, K., Jönsson, L. S., Kolb, H., Lansink, M., et al. (2011) · British Journal of Nutrition · doi:10.1017/s0007114511005460 · Cited by 1,098
The Role of Advanced Glycation End Products in Progression and Complications of Diabetes
Goh, S.-Y., & Cooper, M. E. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1817 · Cited by 987
Ramasamy, R., Vannucci, S. J., Yan, S. S. D., Herold, K., Yan, S. F., & Schmidt, A. M. (2005) · Glycobiology · doi:10.1093/glycob/cwi053 · Cited by 834
Self-citationHammes, H.-P., Du, X., Edelstein, D., Taguchi, T., Matsumura, T., Ju, Q., Lin, J., Bierhaus, A., Nawroth, P., Hannak, D., et al. (2003) · Nature Medicine · doi:10.1038/nm834 · Cited by 785
YONEKURA, H., YAMAMOTO, Y., SAKURAI, S., PETROVA, R. G., ABEDIN, M. J., LI, H., YASUI, K., TAKEUCHI, M., MAKITA, Z., TAKASAWA, S., et al. (2003) · Biochemical Journal · doi:10.1042/bj20021371 · Cited by 716
Casserly, I., & Topol, E. J. (2004) · The Lancet · doi:10.1016/s0140-6736(04)15900-x · Cited by 560
Hofmann, M. A., Lalla, E., Lu, Y., Gleason, M. R., Wolf, B. M., Tanji, N., Ferran, L. J., Kohl, B., Rao, V., Kisiel, W., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci10588 · Cited by 529
Self-citationReceptor for AGE (RAGE): Signaling mechanisms in the pathogenesis of diabetes and its complications
Ramasamy, R., Yan, S. F., & Schmidt, A. M. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06320.x · Cited by 521
Self-citationYan, S. F., Ramasamy, R., Naka, Y., & Schmidt, A. M. (2003) · Circulation Research · doi:10.1161/01.res.0000103862.26506.3d · Cited by 513
Self-citationDevelopment and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice
Yamamoto, Y., Kato, I., Doi, T., Yonekura, H., Ohashi, S., Takeuchi, M., Watanabe, T., Yamagishi, S.-I., Sakurai, S., Takasawa, S., et al. (2001) · Journal of Clinical Investigation · doi:10.1172/jci11771 · Cited by 475
HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins
Bertheloot, D., & Latz, E. (2017) · Cellular & Molecular Immunology · doi:10.1038/cmi.2016.34 · Cited by 455
Lue, L.-F., Walker, D. G., Brachova, L., Beach, T. G., Rogers, J., Schmidt, A. M., Stern, D. M., & Yan, S. D. (2001) · Experimental Neurology · doi:10.1006/exnr.2001.7732 · Cited by 439
Self-citationAge-related vascular stiffening: causes and consequences
Kohn, J. C., Lampi, M. C., & Reinhart-King, C. A. (2015) · Frontiers in Genetics · doi:10.3389/fgene.2015.00112 · Cited by 440
“…the receptor for advanced glycation end products (RAGE) to have downstream effects that include the production of reactive oxygen species, NF-κB inflammatory signaling, and endothelial hyperpermeability (Mullarkey et al., 1990; Wautier et al., 1996, 2001; Bierhaus et al., 1997; Park et al., 1998).”
BackgroundSoro-Paavonen, A., Watson, A. M. D., Li, J., Paavonen, K., Koitka, A., Calkin, A. C., Barit, D., Coughlan, M. T., Drew, B. G., Lancaster, G. I., et al. (2008) · Diabetes · doi:10.2337/db07-1808 · Cited by 407
Rage and arthritis: The G82S polymorphism amplifies the inflammatory response
Hofmann, M. A., Drury, S., Hudson, B. I., Gleason, M. R., Qu, W., Lu, Y., Lalla, E., Chitnis, S., Monteiro, J., Stickland, M. H., et al. (2002) · Genes & Immunity · doi:10.1038/sj.gene.6363861 · Cited by 383
Self-citationThe RAGE axis: A fundamental mechanism signaling danger to the vulnerable vasculature
Yan, S. F., Ramasamy, R., & Schmidt, A. M. (2010) · Circulation Research · doi:10.1161/circresaha.109.212217 · Cited by 381
Self-citationReceptor-dependent cell stress and amyloid accumulation in systemic amyloidosis
Yan, S. D., Zhu, H., Zhu, A., Golabek, A., Du, H., Roher, A., Yu, J., Soto, C., Schmidt, A. M., Stern, D., et al. (2000) · Nature Medicine · doi:10.1038/76216 · Cited by 343
Self-citationYeh, C.-H., Sturgis, L., Haidacher, J., Zhang, X.-N., Sherwood, S. J., Bjercke, R. J., Juhasz, O., Crow, M. T., Tilton, R. G., & Denner, L. (2001) · Diabetes · doi:10.2337/diabetes.50.6.1495 · Cited by 326
Receptor for Advanced-Glycation End Products: Key Modulator of Myocardial Ischemic Injury
Bucciarelli, L. G., Kaneko, M., Ananthakrishnan, R., Harja, E., Lee, L. K., Hwang, Y. C., Lerner, S., Bakr, S., Li, Q., Lu, Y., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.575993 · Cited by 256
Self-citationWendt, T., Tanji, N., Guo, J., Hudson, B. I., Bierhaus, A., Ramasamy, R., Arnold, B., Nawroth, P. P., Yan, S. F., D’Agati, V., et al. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000065100.17349.ca · Cited by 239
Self-citationUnlocking the biology of RAGE in diabetic microvascular complications
Manigrasso, M. B., Juranek, J., Ramasamy, R., & Schmidt, A. M. (2014) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2013.08.002 · Cited by 209
Self-citationMaillard-Lefebvre, H., Boulanger, E., Daroux, M., Gaxatte, C., Hudson, B. I., & Lambert, M. (2009) · Rheumatology · doi:10.1093/rheumatology/kep199 · Cited by 190
The Apolipoprotein E Knockout Mouse: A Model Documenting Accelerated Atherogenesis In Uremia
Buzello, M., Törnig, J., Faulhaber, J., Ehmke, H., Ritz, E., & Amann, K. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000045048.71975.fc · Cited by 167
Hyperglycemia and Endothelial Dysfunction in Atherosclerosis: Lessons from Type 1 Diabetes
Funk, S. D., Yurdagul, A., & Orr, A. W. (2012) · International Journal of Vascular Medicine · doi:10.1155/2012/569654 · Cited by 176
The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases
Senatus, L. M., & Schmidt, A. M. (2017) · Frontiers in Genetics · doi:10.3389/fgene.2017.00187 · Cited by 167
Self-citationApolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond
Pendse, A. A., Arbones-Mainar, J. M., Johnson, L. A., Altenburg, M. K., & Maeda, N. (2009) · Journal of Lipid Research · doi:10.1194/jlr.r800070-jlr200 · Cited by 155
Large animal models of cardiovascular disease
Tsang, H. G., Rashdan, N. A., Whitelaw, C. B. A., Corcoran, B. M., Summers, K. M., & MacRae, V. E. (2016) · Cell Biochemistry and Function · doi:10.1002/cbf.3173 · Cited by 154
Expression analysis of S100 proteins and RAGE in human tumors using tissue microarrays
Hsieh, H.-L., Schäfer, B. W., Sasaki, N., & Heizmann, C. W. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(03)01190-2 · Cited by 151
Yamagishi, S.-I., Adachi, H., Nakamura, K., Matsui, T., Jinnouchi, Y., Takenaka, K., Takeuchi, M., Enomoto, M., Furuki, K., Hino, A., et al. (2006) · Metabolism · doi:10.1016/j.metabol.2006.05.007 · Cited by 148
Chen, J., Huang, X., Halicka, D., Brodsky, S., Avram, A., Eskander, J., Bloomgarden, N. A., Darzynkiewicz, Z., & Goligorsky, M. S. (2006) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00364.2005 · Cited by 142
Aleshin, A., Ananthakrishnan, R., Li, Q., Rosario, R., Lu, Y., Qu, W., Song, F., Bakr, S., Szabolcs, M., D'Agati, V., et al. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01210.2007 · Cited by 143
Self-citationReceptor for advanced glycation end products and age-related macular degeneration
Howes, K. A., Liu, Y., Dunaief, J. L., Milam, A., Frederick, J. M., Marks, A., & Baehr, W. (2004) · Investigative Opthalmology & Visual Science · doi:10.1167/iovs.04-0404 · Cited by 131
Kilhovd, B. K., Juutilainen, A., Lehto, S., Rönnemaa, T., Torjesen, P. A., Birkeland, K. I., Berg, T. J., Hanssen, K. F., & Laakso, M. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000158380.44231.fe · Cited by 122
Yi, X., & Maeda, N. (2006) · Diabetes · doi:10.2337/db06-0251 · Cited by 117
Scavenger Receptors that Recognize Advanced Glycation End Products
Miyazaki, A. (2002) · Trends in Cardiovascular Medicine · doi:10.1016/s1050-1738(02)00171-8 · Cited by 113
Serum advanced glycation end products (AGEs) are associated with insulin resistance
Tan, K. C. B., Shiu, S. W. M., Wong, Y., & Tam, X. (2011) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.1188 · Cited by 111
Role of galectin-3 in diabetic nephropathy
Iacobini, C., Amadio, L., Oddi, G., Ricci, C., Barsotti, P., Missori, S., Sorcini, M., Di Mario, U., Pricci, F., & Pugliese, G. (2003) · Journal of the American Society of Nephrology · doi:10.1097/01.asn.0000077402.95720.b4 · Cited by 99
Shang, L., Ananthakrishnan, R., Li, Q., Quadri, N., Abdillahi, M., Zhu, Z., Qu, W., Rosario, R., Touré, F., Yan, S. F., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010092 · Cited by 93
Self-citationŠebeková, K., Krajčovičová, M., Schinzel, R., Faist, V., Klvanová, J., & Heidland, A. (2001) · European Journal of Nutrition · doi:10.1007/s394-001-8356-3 · Cited by 89
Ebara, T., Conde, K., Kako, Y., Liu, Y., Xu, Y., Ramakrishnan, R., Goldberg, I. J., & Shachter, N. S. (2000) · Journal of Clinical Investigation · doi:10.1172/jci8283 · Cited by 86
Receptor for advanced glycation endproducts (RAGE) deficiency protects against MPTP toxicity
Teismann, P., Sathe, K., Bierhaus, A., Leng, L., Martin, H. L., Bucala, R., Weigle, B., Nawroth, P. P., & Schulz, J. B. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.12.006 · Cited by 75
Stochastic non-enzymatic modification of long-lived macromolecules - A missing hallmark of aging
Fedintsev, A., & Moskalev, A. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101097 · Cited by 72
Liu, M., Yu, Y., Jiang, H., Zhang, L., Zhang, P.-P., Yu, P., Jia, J.-G., Chen, R.-Z., Zou, Y.-Z., & Ge, J.-B. (2013) · Acta Pharmacologica Sinica · doi:10.1038/aps.2013.8 · Cited by 69
Ueno, H., Koyama, H., Shoji, T., Monden, M., Fukumoto, S., Tanaka, S., Otsuka, Y., Mima, Y., Morioka, T., Mori, K., et al. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.04.006 · Cited by 65
Arguing for the motion: yes, RAGE is a receptor for advanced glycation endproducts
Ramasamy, R., Yan, S. F., & Schmidt, A. M. (2007) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200700008 · Cited by 58
Nakamura, T., Sato, E., Fujiwara, N., Kawagoe, Y., Ueda, Y., Suzuki, T., Yamada, S., Takeuchi, M., Fukami, K., Ueda, S., et al. (2009) · Metabolism · doi:10.1016/j.metabol.2009.05.018 · Cited by 53
Association of RAGE gene polymorphisms with sporadic Parkinson's disease in Chinese Han population
Gao, J., Teng, J., Liu, H., Han, X., Chen, B., & Xie, A. (2014) · Neuroscience Letters · doi:10.1016/j.neulet.2013.11.038 · Cited by 31
Saito, R., Araki, S., Yamamoto, Y., & Kusuhara, K. (2017) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2016-0262 · Cited by 8
Metadata
- Authors
- Park, L., Raman, K. G., Lee, K. J., Lu, Y., Ferran, L. J., Chow, W. S., Stern, D., & Schmidt, A. M.
- Venue
- Nature Medicine
- Published
- 1998-09
- Volume
- 4
- Issue
- 9
- Pages
- 1025-1031
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- DOI
- 10.1038/2012
- OpenAlex
- W2073714833
- Cited by
- 1,104
- References
- 5
- FWCI
- 18.53
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.