Autophagy regulates lipid metabolism

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Items 101–167 of 167

1. Organelle-Specific Initiation of Autophagy
   Sica, Valentina, Galluzzi, Lorenzo, Bravo-San Pedro, José Manuel, Izzo, Valentina, Maiuri, Maria Chiara, Kroemer, Guido · 2015 · Molecular Cell
2. The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation
   Kabat, Agnieszka M, Harrison, Oliver J, Riffelmacher, Thomas, Moghaddam, Amin E, Pearson, Claire F, Laing, Adam, Abeler-Dörner, Lucie, Forman, Simon P, Grencis, Richard K, Sattentau, Quentin et al. · 2016 · eLife
3. Autophagy regulates lipid metabolism through selective turnover of NCoR1
   Saito, Tetsuya, Kuma, Akiko, Sugiura, Yuki, Ichimura, Yoshinobu, Obata, Miki, Kitamura, Hiroshi, Okuda, Shujiro, Lee, Hyeon-Cheol, Ikeda, Kazutaka, Kanegae, Yumi et al. · 2019 · Nature Communications
4. Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes
   Lim, Yu-Mi, Lim, Hyejin, Hur, Kyu Yeon, Quan, Wenying, Lee, Hae-Youn, Cheon, Hwanju, Ryu, Dongryeol, Koo, Seung-Hoi, Kim, Hong Lim, Kim, Jin et al. · 2014 · Nature Communications
5. Autophagy deficiency in beta cells leads to compromised unfolded protein response and progression from obesity to diabetes in mice
   Quan, W., Hur, K. Y., Lim, Y., Oh, S. H., Lee, J.-C., Kim, K. H., Kim, G. H., Kim, S.-W., Kim, H. L., Lee, M.-K. et al. · 2012 · Diabetologia
6. Targeting fatty acid metabolism to improve glucose metabolism
   Stinkens, R., Goossens, G. H., Jocken, J. W. E., Blaak, E. E. · 2015 · Obesity Reviews
7. Skeletal muscle autophagy: a new metabolic regulator
   Neel, Brian A., Lin, Yuxi, Pessin, Jeffrey E. · 2013 · Trends in Endocrinology & Metabolism
8. Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization
   Sargeant, Timothy J., Lloyd-Lewis, Bethan, Resemann, Henrike K., Ramos-Montoya, Antonio, Skepper, Jeremy, Watson, Christine J. · 2014 · Nature Cell Biology
9. The Ubiquitin–Proteasome System in Regulation of the Skeletal Muscle Homeostasis and Atrophy: From Basic Science to Disorders
   Kitajima, Yasuo, Yoshioka, Kiyoshi, Suzuki, Naoki · 2020 · The Journal of Physiological Sciences
10. Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway
    Zhang, Yong, Chen, Ming‐liang, Zhou, Yong, Yi, Long, Gao, Yan‐xiang, Ran, Li, Chen, Shi‐hui, Zhang, Ting, Zhou, Xi, Zou, Dan et al. · 2015 · Molecular Nutrition & Food Research
11. New mechanisms of metformin action: Focusing on mitochondria and the gut
    Hur, Kyu Yeon, Lee, Myung‐Shik · 2015 · Journal of Diabetes Investigation
12. Autophagy in hepatic adaptation to stress
    Hazari, Younis, Bravo-San Pedro, José Manuel, Hetz, Claudio, Galluzzi, Lorenzo, Kroemer, Guido · 2020 · Journal of Hepatology
13. The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin Resistance
    Pagel-Langenickel, Ines, Bao, Jianjun, Pang, Liyan, Sack, Michael N. · 2010 · Endocrine Reviews
14. Characterization of macroautophagic flux in vivo using a leupeptin-based assay
    Haspel, Jeffrey, Shaik, Rahamthulla S., Ifedigbo, Emeka, Nakahira, Kiichi, Dolinay, Tamas, Englert, Joshua A., Choi, Augustine M.K. · 2011 · Autophagy
15. Mitochondria Restrict Growth of the Intracellular Parasite Toxoplasma gondii by Limiting Its Uptake of Fatty Acids
    Pernas, Lena, Bean, Camilla, Boothroyd, John C., Scorrano, Luca · 2018 · Cell Metabolism
16. Organelle interplay-peroxisome interactions in health and disease.
    Schrader, Michael, Kamoshita, Maki, Islinger, Markus · 2020 · Journal of Inherited Metabolic Disease
17. Autophagy: Emerging roles in lipid homeostasis and metabolic control
    Christian, Patricia, Sacco, Jennifer, Adeli, Khosrow · 2013 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
18. Non-alcoholic Fatty Liver Disease and Alcohol-Related Liver Disease: Two Intertwined Entities
    Idalsoaga, Francisco, Kulkarni, Anand V., Mousa, Omar Y., Arrese, Marco, Arab, Juan Pablo · 2020 · Frontiers in Medicine
19. <scp>TOR</scp>‐mediated regulation of metabolism in aging
    Antikainen, Henri, Driscoll, Monica, Haspel, Gal, Dobrowolski, Radek · 2017 · Aging Cell
20. Mesenchymal stem cell-based cell-free strategies: safe and effective treatments for liver injury
    Hu, Chenxia, Zhao, Lingfei, Zhang, Lingjian, Bao, Qiongling, Li, Lanjuan · 2020 · Stem Cell Research &amp; Therapy
21. Changes in macroautophagy, chaperone-mediated autophagy, and mitochondrial metabolism in murine skeletal and cardiac muscle during aging
    Zhou, Jin, Chong, Shu Yun, Lim, Andrea, Singh, Brijesh K., Sinha, Rohit A., Salmon, Adam B., Yen, Paul M. · 2017 · Aging
22. Lysosomal adaptation: how the lysosome responds to external cues
    Settembre, C., Ballabio, A. · 2014 · Cold Spring Harbor Perspectives in Biology
23. The Role of Sinusoidal Endothelial Cells in the Axis of Inflammation and Cancer Within the Liver
    Wilkinson, Alex L., Qurashi, Maria, Shetty, Shishir · 2020 · Frontiers in Physiology
24. Age-associated changes in human CD4+ T cells point to mitochondrial dysfunction consequent to impaired autophagy
    Bektas, Arsun, Schurman, Shepherd H., Gonzalez-Freire, Marta, Dunn, Christopher A., Singh, Amit K., Macian, Fernando, Cuervo, Ana Maria, Sen, Ranjan, Ferrucci, Luigi · 2019 · Aging
25. Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits
    Yang, Dun-Sheng, Stavrides, Philip, Saito, Mitsuo, Kumar, Asok, Rodriguez-Navarro, Jose A., Pawlik, Monika, Huo, Chunfeng, Walkley, Steven U., Saito, Mariko, Cuervo, Ana M. et al. · 2014 · Brain
26. Autophagy Ablation in Adipocytes Induces Insulin Resistance and Reveals Roles for Lipid Peroxide and Nrf2 Signaling in Adipose-Liver Crosstalk
    Cai, Jinjin, Pires, Karla M., Ferhat, Maroua, Chaurasia, Bhagirath, Buffolo, Márcio A., Smalling, Rana, Sargsyan, Ashot, Atkinson, Donald L., Summers, Scott A., Graham, Timothy E. et al. · 2018 · Cell Reports
27. Autophagy and the immune function in aging
    Cuervo, Ana Maria, Macian, Fernando · 2014 · Current Opinion in Immunology
28. Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens
    Fernández, Álvaro F, Bárcena, Clea, Martínez-García, Gemma G, Tamargo-Gómez, Isaac, Suárez, María F, Pietrocola, Federico, Castoldi, Francesca, Esteban, Lorena, Sierra-Filardi, Elena, Boya, Patricia et al. · 2017 · Cell Death &amp; Disease
29. Autophagy deficiency in macrophages enhances NLRP3 inflammasome activity and chronic lung disease following silica exposure
    Jessop, Forrest, Hamilton, Raymond F., Rhoderick, Joseph F., Shaw, Pamela K., Holian, Andrij · 2016 · Toxicology and Applied Pharmacology
30. Liraglutide Alleviates Hepatic Steatosis by Activating the TFEB-Regulated Autophagy-Lysosomal Pathway
    Fang, Yunyun, Ji, Linlin, Zhu, Chaoyu, Xiao, Yuanyuan, Zhang, Jingjing, Lu, Junxi, Yin, Jun, Wei, Li · 2020 · Frontiers in Cell and Developmental Biology
31. Pyroptosis: An Inflammatory Link Between NAFLD and NASH With Potential Therapeutic Implications
    Beier, Juliane I., Banales, Jesus M. · 2018 · Journal of Hepatology
32. Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy
    Yamamuro, Tadashi, Kawabata, Tsuyoshi, Fukuhara, Atsunori, Saita, Shotaro, Nakamura, Shuhei, Takeshita, Hikari, Fujiwara, Mari, Enokidani, Yusuke, Yoshida, Gota, Tabata, Keisuke et al. · 2020 · Nature Communications
33. Lipotoxicity in NASH
    Fuchs, Michael, Sanyal, Arun J. · 2012 · Journal of Hepatology
34. Drilling for Oil: Tumor-Surrounding Adipocytes Fueling Cancer
    Attané, Camille, Muller, Catherine · 2020 · Trends in Cancer
35. Autophagy in chronic liver diseases: the two faces of Janus
    Gual, Philippe, Gilgenkrantz, Hélène, Lotersztajn, Sophie · 2017 · American Journal of Physiology-Cell Physiology
36. Plin4-Dependent Lipid Droplets Hamper Neuronal Mitophagy in the MPTP/p-Induced Mouse Model of Parkinson’s Disease
    Han, Xiaojuan, Zhu, Jialei, Zhang, Xinlei, Song, Qiqi, Ding, Jianhua, Lu, Ming, Sun, Sifan, Hu, Gang · 2018 · Frontiers in Neuroscience
37. Skeletal muscle, autophagy, and physical activity: the ménage à trois of metabolic regulation in health and disease
    Vainshtein, Anna, Grumati, Paolo, Sandri, Marco, Bonaldo, Paolo · 2014 · Journal of Molecular Medicine
38. Hepatic Stellate Cells and Liver Fibrosis
    Puche, Juan E., Saiman, Yedidya, Friedman, Scott L. · 2013 · Comprehensive Physiology
39. Evidence for association of mitochondrial metabolism alteration with lipid accumulation in aging rats
    Zhao, Lin, Zou, Xuan, Feng, Zhihui, Luo, Cheng, Liu, Jing, Li, Hao, Chang, Liao, Wang, Hui, Li, Yuan, Long, Jiangang et al. · 2014 · Experimental Gerontology
40. High-Mobility Group Box 1 Is Dispensable for Autophagy, Mitochondrial Quality Control, and Organ Function in Vivo
    Huebener, Peter, Gwak, Geum-Youn, Pradere, Jean-Philippe, Quinzii, Catarina M., Friedman, Richard, Lin, Chyuan-Sheng, Trent, Chad M., Mederacke, Ingmar, Zhao, Enpeng, Dapito, Dianne H. et al. · 2014 · Cell Metabolism
41. Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr ⁶⁸² -phosphorylated APP βCTF
    Im, Eunju, Jiang, Ying, Stavrides, Philip H., Darji, Sandipkumar, Erdjument-Bromage, Hediye, Neubert, Thomas A., Choi, Jun Yong, Wegiel, Jerzy, Lee, Ju-Hyun, Nixon, Ralph A. · 2023 · Science Advances
42. Ursolic acid improves lipid and glucose metabolism in high‐fat‐fed C57BL/6J mice by activating peroxisome proliferator‐activated receptor alpha and hepatic autophagy
    Jia, Yaoyao, Kim, Seyoung, Kim, Jiyoung, Kim, Bobae, Wu, Chunyan, Lee, Ji Hae, Jun, Hee‐jin, Kim, Nahyun, Lee, Dongho, Lee, Sung‐Joon · 2015 · Molecular Nutrition &amp; Food Research
43. Autophagy Protects Cells From HCV-Induced Defects in Lipid Metabolism
    Vescovo, Tiziana, Romagnoli, Alessandra, Perdomo, Ariel Basulto, Corazzari, Marco, Ciccosanti, Fabiola, Alonzi, Tonino, Nardacci, Roberta, Ippolito, Giuseppe, Tripodi, Marco, Garcia–Monzon, Carmelo et al. · 2012 · Gastroenterology
44. Induction of genuine autophagy by cationic lipids in mammalian cells
    Man, Na, Chen, Yong, Zheng, Fang, Zhou, Wei, Wen, Long-Ping · 2010 · Autophagy
45. Eating the dead to keep atherosclerosis at bay
    Brophy, Megan L., Dong, Yunzhou, Wu, Hao, Rahman, H. N. Ashiqur, Song, Kai, Chen, Hong · 2017 · Frontiers in Cardiovascular Medicine
46. Calorie restriction and its impact on gut microbial composition and global metabolism
    Zheng, Xiaojiao, Wang, Shouli, Jia, Wei · 2018 · Frontiers of Medicine
47. Comprehensive autophagy evaluation in cardiac disease models
    Kaludercic, Nina, Maiuri, Maria Chiara, Kaushik, Susmita, Fernández, Álvaro F, de Bruijn, Jenny, Castoldi, Francesca, Chen, Yun, Ito, Jumpei, Mukai, Risa, Murakawa, Tomokazu et al. · 2020 · Cardiovascular Research
48. The contribution of melanoregulin to microtubule-associated protein 1 light chain 3 (LC3) associated phagocytosis in retinal pigment epithelium
    Frost, Laura S., Lopes, Vanda S., Bragin, Alvina, Reyes-Reveles, Juan, Brancato, Jennifer, Cohen, Art, Mitchell, Claire H., Williams, David S., Boesze-Battaglia, Kathleen · 2015 · Molecular Neurobiology
49. Lysoplex: An efficient toolkit to detect DNA sequence variations in the autophagy-lysosomal pathway
    Di Fruscio, Giuseppina, Schulz, Angela, De Cegli, Rossella, Savarese, Marco, Mutarelli, Margherita, Parenti, Giancarlo, Banfi, Sandro, Braulke, Thomas, Nigro, Vincenzo, Ballabio, Andrea · 2015 · Autophagy
50. A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia
    Zhou, Jin, Waskowicz, Lauren R., Lim, Andrea, Liao, Xiao-Hui, Lian, Brian, Masamune, Hiroko, Refetoff, Samuel, Tran, Brian, Koeberl, Dwight D., Yen, Paul M. · 2019 · Thyroid®
51. RETRACTED: Apelin-13 impedes foam cell formation by activating Class III PI3K/Beclin-1-mediated autophagic pathway
    Yao, Feng, Lv, Yun-Cheng, Zhang, Min, Xie, Wei, Tan, Yu-Lin, Gong, Duo, Cheng, Hai-Peng, Liu, Dan, Li, Liang, Liu, Xiao-Yan et al. · 2015 · Biochemical and Biophysical Research Communications · Retracted
52. Schwann cell dedifferentiation-associated demyelination leads to exocytotic myelin clearance in inflammatory segmental demyelination
    Jang, So Young, Yoon, Byeol-A, Shin, Yoon Kyung, Yun, Seoug Hoon, Jo, Young Rae, Choi, Yun Young, Ahn, Meejung, Shin, Taekyun, Park, Joo In, Kim, Jong Kuk et al. · 2017 · Glia
53. Pharmacological Upregulation of Microglial Lipid Droplet Alleviates Neuroinflammation and Acute Ischemic Brain Injury
    Li, Huiya, Liu, Pinyi, Deng, Shiji, Zhu, Liwen, Cao, Xiang, Bao, Xinyu, Xia, Shengnan, Xu, Yun, Zhang, Bing · 2023 · Inflammation
54. Ameliorative Effect of Annona muricata (Graviola) Extract on Hyperglycemia Induced Hepatic Damage in Type 2 Diabetic Mice
    Son, Yiseul, Lee, Heaji, Son, Su-Young, Lee, Choong-Hwan, Kim, Sun-Yeou, Lim, Yunsook · 2021 · Antioxidants
55. Hepatic autophagy contributes to the metabolic response to dietary protein restriction
    Henagan, Tara M., Laeger, Thomas, Navard, Alexandra M., Albarado, Diana, Noland, Robert C., Stadler, Krisztian, Elks, Carrie M., Burk, David, Morrison, Christopher D. · 2016 · Metabolism
56. The Proton-Coupled Monocarboxylate Transporter Hermes Is Necessary for Autophagy during Cell Death
    Velentzas, Panagiotis D., Zhang, Lejie, Das, Gautam, Chang, Tsun-Kai, Nelson, Charles, Kobertz, William R., Baehrecke, Eric H. · 2018 · Developmental Cell
57. Islet amyloid and type 2 diabetes: overproduction or inadequate clearance and detoxification?
    Gupta, Dhananjay, Leahy, Jack L. · 2014 · Journal of Clinical Investigation
58. Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome
    Bernier, Michel, Harney, Dylan, Koay, Yen Chin, Diaz, Antonio, Singh, Abhishek, Wahl, Devin, Pulpitel, Tamara, Ali, Ahmed, Guiterrez, Vince, Mitchell, Sarah J. et al. · 2020 · npj Aging and Mechanisms of Disease
59. BCAA metabolism in pancreatic cancer affects lipid balance by regulating fatty acid import into mitochondria
    Gotvaldová, Klára, Špačková, Jitka, Novotný, Jiří, Baslarová, Kamila, Ježek, Petr, Rossmeislová, Lenka, Gojda, Jan, Smolková, Katarína · 2024 · Cancer &amp; Metabolism
60. Autophagy: a killer or guardian of vascular smooth muscle cells
    Zhang, Yin-Yu, Shi, Ya-Ning, Zhu, Neng, Wang, Wei, Deng, Chang-Feng, Xie, Xue-Jiao, Liao, Duan-Fang, Qin, Li · 2020 · Journal of Drug Targeting
61. Manipulation of selective macroautophagy by pathogens at a glance
    Cong, Yingying, Dinesh Kumar, Nilima, Mauthe, Mario, Verlhac, Pauline, Reggiori, Fulvio · 2020 · Journal of Cell Science
62. Role of Ca²⁺ channels in non-alcoholic fatty liver disease and their implications for therapeutic strategies (Review)
    Chen, Xingyue, Zhang, Li, Zheng, Liming, Tuo, Biguang · 2022 · International Journal of Molecular Medicine
63. Context- and Dose-Dependent Modulatory Effects of Naringenin on Survival and Development of Drosophila Melanogaster
    Chattopadhyay, Debarati, Sen, Soumadeep, Chatterjee, Rishita, Roy, Debasish, James, Joel, Thirumurugan, Kavitha · 2016 · Biogerontology
64. Mild mitochondrial uncoupling induces HSL/ATGL-independent lipolysis relying on a form of autophagy in 3T3-L1 adipocytes
    Demine, Stéphane, Tejerina, Silvia, Bihin, Benoît, Thiry, Marc, Reddy, Nagabushana, Renard, Patricia, Raes, Martine, Jadot, Michel, Arnould, Thierry · 2018 · Journal of Cellular Physiology
65. The pivotal role of dysregulated autophagy in the progression of non-alcoholic fatty liver disease
    Shen, Qiaohui, Yang, Ming, Wang, Song, Chen, Xingyu, Chen, Sulan, Zhang, Rui, Xiong, Zhuang, Leng, Yan · 2024 · Frontiers in Endocrinology
66. Entosis Acts as a Novel Way within Sertoli Cells to Eliminate Spermatozoa in Seminiferous Tubule
    Ahmed, Nisar, Yang, Ping, Huang, Yufei, Chen, Hong, Liu, Tengfei, Wang, Lingling, Nabi, Fazul, Liu, Yi, Chen, Qiusheng · 2017 · Frontiers in Physiology
67. Peroxisomal integrity in demyelination-associated microglia enables cellular debris clearance and myelin renewal in mice
    Barnes-Vélez, Joseph A., Zhang, Xiaohong, Peña Señeriz, Yaren L., Scott, Kiersten A., Guan, Yinglu, Hu, Jian · 2026 · Journal of Clinical Investigation