Integrating single-cell transcriptomic data across different conditions, technologies, and species
Butler, Andrew, Hoffman, Paul, Smibert, Peter, Papalexi, Efthymia, Satija, Rahul·2018·Nature Biotechnology
DOI 10.1038/nbt.4096
Cited by (1,197)
Items 101–200 of 1,197
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- hdWGCNA identifies co-expression networks in high-dimensional transcriptomics dataMorabito, Samuel, Reese, Fairlie, Rahimzadeh, Negin, Miyoshi, Emily, Swarup, Vivek · 2023 · Cell Reports Methods
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- MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indicesMcGinnis, Christopher S., Patterson, David M., Winkler, Juliane, Conrad, Daniel N., Hein, Marco Y., Srivastava, Vasudha, Hu, Jennifer L., Murrow, Lyndsay M., Weissman, Jonathan S., Werb, Zena et al. · 2019 · Nature Methods
- A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumorsMichal Slyper, Caroline B. M. Porter, Orr Ashenberg, Julia Waldman, Eugene Drokhlyansky, Isaac Wakiro, Christopher S. Smillie, Gabriela Smith-Rosario, Jingyi Wu, Danielle Ashley Dionne et al. · 2020 · Nature Medicine
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- Single-cell transcriptomic profiling of the aging mouse brainXimerakis, Methodios, Lipnick, Scott L., Innes, Brendan T., Simmons, Sean K., Adiconis, Xian, Dionne, Danielle, Mayweather, Brittany A., Nguyen, Lan, Niziolek, Zachary, Ozek, Ceren et al. · 2019 · Nature Neuroscience
- scmap: projection of single-cell RNA-seq data across data sets2018
- Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer’s diseaseOlah, Marta, Menon, Vilas, Habib, Naomi, Taga, Mariko F., Ma, Yiyi, Yung, Christina J., Cimpean, Maria, Khairallah, Anthony, Coronas-Samano, Guillermo, Sankowski, Roman et al. · 2020 · Nature Communications
- A comparison of automatic cell identification methods for single-cell RNA sequencing dataAbdelaal, Tamim, Michielsen, Lieke, Cats, Davy, Hoogduin, Dylan, Mei, Hailiang, Reinders, Marcel J. T., Mahfouz, Ahmed · 2019 · Genome Biology
- Machine learning for integrating data in biology and medicine: principles, practice, and opportunitiesZitnik, Marinka, Nguyen, Francis, Wang, Bo, Leskovec, Jure, Goldenberg, Anna, Hoffman, Michael M. · 2019 · Information Fusion
- Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinomaChen, Zhaohui, Zhou, Lijie, Liu, Lilong, Hou, Yaxin, Xiong, Ming, Yang, Yu, Hu, Junyi, Chen, Ke · 2020 · Nature Communications
- Probabilistic harmonization and annotation of single‐cell transcriptomics data with deep generative modelsXu, Chenling, Lopez, Romain, Mehlman, Edouard, Regier, Jeffrey, Jordan, Michael I, Yosef, Nir · 2021 · Molecular Systems Biology
- Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflowsDenisenko, Elena, Guo, Belinda B., Jones, Matthew, Hou, Rui, de Kock, Leanne, Lassmann, Timo, Poppe, Daniel, Clément, Olivier, Simmons, Rebecca K., Lister, Ryan et al. · 2020 · Genome Biology
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- Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcomaZhou, Yan, Yang, Dong, Yang, Qingcheng, Lv, Xiaobin, Huang, Wentao, Zhou, Zhenhua, Wang, Yaling, Zhang, Zhichang, Yuan, Ting, Ding, Xiaomin et al. · 2020 · Nature Communications
- Ageing hallmarks exhibit organ-specific temporal signaturesSchaum, Nicholas, Lehallier, Benoit, Hahn, Oliver, Pálovics, Róbert, Hosseinzadeh, Shayan, Lee, Song E., Sit, Rene, Lee, Davis P., Losada, Patricia Morán, Zardeneta, Macy E. et al. · 2020 · Nature
- Immune Landscape of Viral- and Carcinogen-Driven Head and Neck CancerAnthony Richard Cillo, Cornelius H. L. Kürten, Tracy Tabib, Zengbiao Qi, Sayali Onkar, Ting Wang, Angen Liu, Umamaheswar Duvvuri, Seungwon Kim, Ryan J. Soose et al. · 2020 · Immunity
- Comparison of methods and resources for cell-cell communication inference from single-cell RNA-Seq dataDimitrov, Daniel, Türei, Dénes, Garrido-Rodriguez, Martin, Burmedi, Paul L., Nagai, James S., Boys, Charlotte, Ramirez Flores, Ricardo O., Kim, Hyojin, Szalai, Bence, Costa, Ivan G. et al. · 2022 · Nature Communications
- Mapping the temporal and spatial dynamics of the human endometrium in vivo and in vitro2021
- scGen predicts single-cell perturbation responsesLotfollahi, Mohammad, Wolf, F. Alexander, Theis, Fabian J. · 2019 · Nature Methods
- Proteogenomic and metabolomic characterization of human glioblastomaWang, Liang-Bo, Karpova, Alla, Gritsenko, Marina A., Kyle, Jennifer E., Cao, Song, Li, Yize, Rykunov, Dmitry, Colaprico, Antonio, Rothstein, Joseph H., Hong, Runyu et al. · 2021 · Cancer Cell
- TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 ImmunotherapyMolgora, Martina, Esaulova, Ekaterina, Vermi, William, Hou, Jinchao, Chen, Yun, Luo, Jingqin, Brioschi, Simone, Bugatti, Mattia, Omodei, Andrea Salvatore, Ricci, Biancamaria et al. · 2020 · Cell
- TISCH2: expanded datasets and new tools for single-cell transcriptome analyses of the tumor microenvironmentYa Han, Yuting Wang, Xin Dong, Dongqing Sun, Zhaoyang Liu, Jiali Yue, Haiyun Wang, Taiwen Li, Chenfei Wang · 2022 · Nucleic Acids Research
- Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer’s diseaseMorabito, Samuel, Miyoshi, Emily, Michael, Neethu, Shahin, Saba, Martini, Alessandra Cadete, Head, Elizabeth, Silva, Justine, Leavy, Kelsey, Perez-Rosendahl, Mari, Swarup, Vivek · 2021 · Nature Genetics
- A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and OrganoidsLiuliu Yang, Yuling Han, Benjamin E. Nilsson-Payant, Vikas Gupta, Pengfei Wang, Xiaohua Duan, Xuming Tang, Jiajun Zhu, Zeping Zhao, Fabrice Jaffré et al. · 2020 · Cell stem cell
- Establishing Cerebral Organoids as Models of Human-Specific Brain EvolutionPollen, Alex A., Bhaduri, Aparna, Andrews, Madeline G., Nowakowski, Tomasz J., Meyerson, Olivia S., Mostajo-Radji, Mohammed A., Di Lullo, Elizabeth, Alvarado, Beatriz, Bedolli, Melanie, Dougherty, Max L. et al. · 2019 · Cell
- Locally renewing resident synovial macrophages provide a protective barrier for the jointStephan Culemann, Anika Grüneboom, José Ángel Nicolás-Ávila, Daniela Weidner, Katrin F. Lämmle, Tobias Rothe, Juan Antonio Quintana, Philipp Kirchner, Branislav Krljanac, Martin Eberhardt et al. · 2019 · Nature
- Automated optimized parameters for T-distributed stochastic neighbor embedding improve visualization and analysis of large datasetsAnna C. Belkina, Christopher O. Ciccolella, Rina Anno, Richard Halpert, Josef Špidlen, Jennifer E Snyder-Cappione · 2019 · Nature Communications
- Single-cell landscape of immunological responses in patients with COVID-19Zhang, Ji-Yuan, Wang, Xiang-Ming, Xing, Xudong, Xu, Zhe, Zhang, Chao, Song, Jin-Wen, Fan, Xing, Xia, Peng, Fu, Jun-Liang, Wang, Si-Yu et al. · 2020 · Nature Immunology
- Cell stress in cortical organoids impairs molecular subtype specificationBhaduri, Aparna, Andrews, Madeline G., Mancia Leon, Walter, Jung, Diane, Shin, David, Allen, Denise, Jung, Dana, Schmunk, Galina, Haeussler, Maximilian, Salma, Jahan et al. · 2020 · Nature
- Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case reportArboleda-Velasquez, Joseph F., Lopera, Francisco, O’Hare, Michael, Delgado-Tirado, Santiago, Marino, Claudia, Chmielewska, Natalia, Saez-Torres, Kahira L., Amarnani, Dhanesh, Schultz, Aaron P., Sperling, Reisa A. et al. · 2019 · Nature Medicine
- Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and HumanHuize Pan, Chenyi Xue, Benjamin J. Auerbach, Jiaxin Fan, Alexander C. Bashore, Jian Guo Cui, Dina Y. Yang, Sarah B. Trignano, Wen Liu, Jianting Shi et al. · 2020 · Circulation
- Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinomaKevin Bi, Meng Xiao He, Ziad Bakouny, Abhay Kanodia, Sara Napolitano, Jingyi Wu, Grace Grimaldi, David A. Braun, Michael S. Cuoco, Angie Mayorga et al. · 2021 · Cancer Cell
- Spatiotemporal Developmental Trajectories in the Arabidopsis Root Revealed Using High-Throughput Single Cell RNA SequencingTom Denyer, Xiaoli Ma, Simon Klesen, Emanuele Scacchi, Kay Nieselt, Marja C.P. Timmermans · 2018 · Developmental Cell
- Multi-omics single-cell data integration and regulatory inference with graph-linked embeddingCao, Zhi-Jie, Gao, Ge · 2022 · Nature Biotechnology
- Microglial Remodeling of the Extracellular Matrix Promotes Synapse PlasticityNguyen, Phi T., Dorman, Leah C., Pan, Simon, Vainchtein, Ilia D., Han, Rafael T., Nakao-Inoue, Hiromi, Taloma, Sunrae E., Barron, Jerika J., Molofsky, Ari B., Kheirbek, Mazen A. et al. · 2020 · Cell
- A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic ScreensGasperini, Molly, Hill, Andrew J., McFaline-Figueroa, José L., Martin, Beth, Kim, Seungsoo, Zhang, Melissa D., Jackson, Dana, Leith, Anh, Schreiber, Jacob, Noble, William S. et al. · 2019 · Cell
- scRepertoire: An R-based toolkit for single-cell immune receptor analysisNicholas C. Borcherding, Nicholas L. Bormann, Gloria Kraus · 2020 · F1000Research
- Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell TranscriptomicsHao Wu, Kohei Uchimura, Erinn L. Donnelly, Yuhei Kirita, Samantha A. Morris, Benjamin D. Humphreys · 2018 · Cell stem cell
- Microanatomy of the Human Atherosclerotic Plaque by Single-Cell TranscriptomicsMarie A.C. Depuydt, Koen H.M. Prange, Lotte Slenders, Tiit Örd, D. Elbersen, Arjan Boltjes, Saskia C.A. de Jager, Folkert Wouter Asselbergs, Gert Jan de Borst, Einari Aavik et al. · 2020 · Circulation Research
- Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironmentLam, Khiem C., Araya, Romina E., Huang, April, Chen, Quanyi, Di Modica, Martina, Rodrigues, Richard R., Lopès, Amélie, Johnson, Sarah B., Schwarz, Benjamin, Bohrnsen, Eric et al. · 2021 · Cell
- Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomasDeng, Qing, Han, Guangchun, Puebla-Osorio, Nahum, Ma, Man Chun John, Strati, Paolo, Chasen, Beth, Dai, Enyu, Dang, Minghao, Jain, Neeraj, Yang, Haopeng et al. · 2020 · Nature Medicine
- Allergic inflammatory memory in human respiratory epithelial progenitor cells2018
- Generation of Functional Human 3D Cortico-Motor AssembloidsAndersen, Jimena, Revah, Omer, Miura, Yuki, Thom, Nicholas, Amin, Neal D., Kelley, Kevin W., Singh, Mandeep, Chen, Xiaoyu, Thete, Mayuri Vijay, Walczak, Elisabeth M. et al. · 2020 · Cell
- Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar RegenerationJinwook Choi, Jong-Eun Park, Georgia Tsagkogeorga, Motoko Yanagita, Bon‐Kyoung Koo, Namshik Han, Joo‐Hyeon Lee · 2020 · Cell stem cell
- The human body at cellular resolution: the NIH Human Biomolecular Atlas ProgramHuBMAP Consortium, Writing Group, Snyder, Michael P., Lin, Shin, Posgai, Amanda, Atkinson, Mark, Regev, Aviv, Rood, Jennifer, Rozenblatt-Rosen, Orit, Gaffney, Leslie et al. · 2019 · Nature
- The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to SpermatidsBrian P. Hermann, Keren Cheng, Anukriti Singh, Lorena Roa-de la Cruz, Kazadi Nadine Mutoji, I-Chung Chen, Heidi I. S. Gildersleeve, Jake D. Lehle, Max Mayo, Birgit Westernströer et al. · 2018 · Cell Reports
- Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer.Rodrigo Nalio Ramos, Y. Missolo-Koussou, Yohan Gerber-Ferder, C. Bromley, M. Bugatti, N. Núñez, Jimena Tosello Boari, W. Richer, L. Menger, Jordan Denizeau et al. · 2022 · Cell
- Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigenVardhana, Santosha A., Hwee, Madeline A., Berisa, Mirela, Wells, Daniel K., Yost, Kathryn E., King, Bryan, Smith, Melody, Herrera, Pamela S., Chang, Howard Y., Satpathy, Ansuman T. et al. · 2020 · Nature Immunology
- A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestationPolioudakis, Damon, de la Torre-Ubieta, Luis, Langerman, Justin, Elkins, Andrew G., Shi, Xu, Stein, Jason L., Vuong, Celine K., Nichterwitz, Susanne, Gevorgian, Melinda, Opland, Carli K. et al. · 2019 · Neuron
- Neuroinflammatory astrocyte subtypes in the mouse brainHasel, Philip, Rose, Indigo V. L., Sadick, Jessica S., Kim, Rachel D., Liddelow, Shane A. · 2021 · Nature Neuroscience
- The Human and Mouse Enteric Nervous System at Single-Cell ResolutionEugene Drokhlyansky, Christopher S. Smillie, Nicholas Van Wittenberghe, Maria Ericsson, Gabriel Kenneth Griffin, Gökçen Eraslan, Danielle Ashley Dionne, Michael S. Cuoco, Max N. Goder-Reiser, Tatyana Y. Sharova et al. · 2020 · Cell
- Multiplexed detection of proteins, transcriptomes, clonotypes and CRISPR perturbations in single cellsMimitou, Eleni P., Cheng, Anthony, Montalbano, Antonino, Hao, Stephanie, Stoeckius, Marlon, Legut, Mateusz, Roush, Timothy, Herrera, Alberto, Papalexi, Efthymia, Ouyang, Zhengqing et al. · 2019 · Nature Methods
- Single-cell transcriptomes of the regenerating intestine reveal a revival stem cellArshad Ayyaz, Sandeep Kumar, Bruno Sangiorgi, Bibaswan Ghoshal, Jessica Gosio, Shaida Ouladan, Mardi Fink, Seda Barutcu, Daniel Trcka, Jess Shen et al. · 2019 · Nature
- Scalable, multimodal profiling of chromatin accessibility, gene expression and protein levels in single cellsMimitou, Eleni P., Lareau, Caleb A., Chen, Kelvin Y., Zorzetto-Fernandes, Andre L., Hao, Yuhan, Takeshima, Yusuke, Luo, Wendy, Huang, Tse-Shun, Yeung, Bertrand Z., Papalexi, Efthymia et al. · 2021 · Nature Biotechnology
- Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune FunctionShifrut, Eric, Carnevale, Julia, Tobin, Victoria, Roth, Theodore L., Woo, Jonathan M., Bui, Christina T., Li, P. Jonathan, Diolaiti, Morgan E., Ashworth, Alan, Marson, Alexander · 2018 · Cell
- Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchyCharles Couturier, Shamini Ayyadhury, Phuong Uyen Le, Javad Nadaf, Jean Monlong, Gabriele Riva, Redouane Allache, Salma Baig, Xiaohua Yan, Mathieu Bourgey et al. · 2020 · Nature Communications
- Single-cell atlas of lineage states, tumor microenvironment, and subtype-specific expression programs in gastric cancerKumar, Vikrant, Ramnarayanan, Kalpana, Sundar, Raghav, Padmanabhan, Nisha, Srivastava, Supriya, Koiwa, Mayu, Yasuda, Tadahito, Koh, Vivien, Huang, Kie Kyon, Tay, Su Ting et al. · 2022 · Cancer Discovery
- Profiling Cell Type Abundance and Expression in Bulk Tissues with CIBERSORTxChloé Beate Steen, Chih Long Liu, Ash A. Alizadeh, Aaron M. Newman · 2020 · Methods in molecular biology
- Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication in the Mouse HeartDaniel A. Skelly, Galen T Squiers, Micheal A. McLellan, Mohan T. Bolisetty, Paul Robson, Nadia A Rosenthal, Alexander Ruvantha Pinto · 2018 · Cell Reports
- Three tissue resident macrophage subsets coexist across organs with conserved origins and life cyclesDick, Sarah A., Wong, Anthony, Hamidzada, Homaira, Nejat, Sara, Nechanitzky, Robert, Vohra, Shabana, Mueller, Brigitte, Zaman, Rysa, Kantores, Crystal, Aronoff, Laura et al. · 2022 · Science Immunology
- Transcriptional and Cellular Diversity of the Human HeartTucker, Nathan R., Chaffin, Mark, Fleming, Stephen J., Hall, Amelia W., Parsons, Victoria A., Bedi, Kenneth C., Akkad, Amer-Denis, Herndon, Caroline N., Arduini, Alessandro, Papangeli, Irinna et al. · 2020 · Circulation
- Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injuryNona Farbehi, Ralph Patrick, Aude Dorison, Munira Xaymardan, Vaibhao C. Janbandhu, Katharina Wystub-Lis, Joshua W. K. Ho, Robert E. Nordon, Richard Paul Harvey · 2019 · eLife
- Stem-like CD8 T cells mediate response of adoptive cell immunotherapy against human cancerSri Krishna, Frank J. Lowery, Amy R. Copeland, Erol Bahadiroglu, Ratnadeep Mukherjee, Li Jia, James Anibal, Abraham Sachs, Serifat O. Adebola, Devikala Gurusamy et al. · 2020 · Science
- Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s diseaseKamath, Tushar, Abdulraouf, Abdulraouf, Burris, S. J., Langlieb, Jonah, Gazestani, Vahid, Nadaf, Naeem M., Balderrama, Karol, Vanderburg, Charles, Macosko, Evan Z. · 2022 · Nature Neuroscience
- Single-Cell RNA Sequencing Resolves Molecular Relationships Among Individual Plant CellsKook Hui Ryu, Ling Huang, Hyun Min Kang, John Schiefelbein · 2019 · PLANT PHYSIOLOGY
- Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease modelWang, Shoutang, Mustafa, Meer, Yuede, Carla M., Salazar, Santiago Viveros, Kong, Philip, Long, Hua, Ward, Michael, Siddiqui, Omer, Paul, Robert, Gilfillan, Susan et al. · 2020 · Journal of Experimental Medicine
- Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infectionYao, Chen, Sun, Hong-Wei, Lacey, Neal E., Ji, Yun, Moseman, E. Ashley, Shih, Han-Yu, Heuston, Elisabeth F., Kirby, Martha, Anderson, Stacie, Cheng, Jun et al. · 2019 · Nature Immunology
- Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancerHuang, Huocong, Wang, Zhaoning, Zhang, Yuqing, Pradhan, Rachana N., Ganguly, Debolina, Chandra, Raghav, Murimwa, Gilbert, Wright, Steven, Gu, Xiaowu, Maddipati, Ravikanth et al. · 2022 · Cancer Cell
- Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomicsHamad S. Alshetaiwi, Nicholas Pervolarakis, Laura Lynn McIntyre, Dennis Ma, Quy Nguyen, Jan A. Rath, Kevin Nee, Grace A. Hernandez, Katrina T. Evans, Leona Torosian et al. · 2020 · Science Immunology
- Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer’s disease risk genesSchwartzentruber, Jeremy, Cooper, Sarah, Liu, Jimmy Z., Barrio-Hernandez, Inigo, Bello, Erica, Kumasaka, Natsuhiko, Young, Adam M. H., Franklin, Robin J. M., Johnson, Toby, Estrada, Karol et al. · 2021 · Nature Genetics
- Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary FibrosisTing Xie, Yizhou Wang, Nan Deng, Guanling Huang, Forough Taghavifar, Yan Geng, Ningshan Liu, Vrishika Kulur, Changfu Yao, Peter Chen et al. · 2018 · Cell Reports
- Spatiotemporal analysis of human intestinal development at single-cell resolutionDavid Fawkner-Corbett, Agne Antanaviciute, Kaushal Parikh, Marta Jagielowicz, Ana Sousa Gerós, Tarun Gupta, Neil Ashley, Doran Khamis, Darren J. Fowler, Edward R. Morrissey et al. · 2021 · Cell
- Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neuronsNagy, Corina, Maitra, Malosree, Tanti, Arnaud, Suderman, Matthew, Théroux, Jean-Francois, Davoli, Maria Antonietta, Perlman, Kelly, Yerko, Volodymyr, Wang, Yu Chang, Tripathy, Shreejoy J. et al. · 2020 · Nature Neuroscience
- The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2020 updateVahid Jalili, Enis Afgan, Qiang Gu, Dave Clements, Daniel J Blankenberg, Jeremy Goecks, James Taylor, Anton Nekrutenko · 2020 · Nucleic Acids Research
- Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic CellsCharles‐Antoine Dutertre, Étienne Becht, Sergio Erdal Irac, Ahad Khalilnezhad, Vipin Narang, Shabnam Khalilnezhad, Pei Ying Ng, Lucas L. van den Hoogen, Jing Yao Leong, Bernett Teck Kwong Lee et al. · 2019 · Immunity
- Microscopic examination of spatial transcriptome using Seq-ScopeCho, Chun-Seok, Xi, Jingyue, Si, Yichen, Park, Sung-Rye, Hsu, Jer-En, Kim, Myungjin, Jun, Goo, Kang, Hyun Min, Lee, Jun Hee · 2021 · Cell
- A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitisKrienke, Christina, Kolb, Laura, Diken, Elif, Streuber, Michael, Kirchhoff, Sarah, Bukur, Thomas, Akilli-Öztürk, Özlem, Kranz, Lena M., Berger, Hendrik, Petschenka, Jutta et al. · 2021 · Science
- muscat detects subpopulation-specific state transitions from multi-sample multi-condition single-cell transcriptomics dataCrowell, Helena L., Soneson, Charlotte, Germain, Pierre-Luc, Calini, Daniela, Collin, Ludovic, Raposo, Catarina, Malhotra, Dheeraj, Robinson, Mark D. · 2020 · Nature Communications
- Capillary cell-type specialization in the alveolusGillich, Astrid, Zhang, Fan, Farmer, Colleen G., Travaglini, Kyle J., Tan, Serena Y., Gu, Mingxia, Zhou, Bin, Feinstein, Jeffrey A., Krasnow, Mark A., Metzger, Ross J. · 2020 · Nature
- MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine FateAbbie S. Ireland, Alexi M. Micinski, David W. Kastner, Bingqian Guo, Sarah J. Wait, Kyle B. Spainhower, Christopher C. Conley, Opal S. Chen, Matthew R. Guthrie, Danny Soltero et al. · 2020 · Cancer Cell
- Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASHDudek, Michael, Pfister, Dominik, Donakonda, Sainitin, Filpe, Pamela, Schneider, Annika, Laschinger, Melanie, Hartmann, Daniel, Hüser, Norbert, Meiser, Philippa, Bayerl, Felix et al. · 2021 · Nature
- A test metric for assessing single-cell RNA-seq batch correctionBüttner, Maren, Miao, Zhichao, Wolf, F. Alexander, Teichmann, Sarah A., Theis, Fabian J. · 2019 · Nature Methods
- Progressive immune dysfunction with advancing disease stage in renal cell carcinomaDavid A. Braun, Kelly Street, Kelly P. Burke, David L. Cookmeyer, Thomas Denize, Christina Bligaard Pedersen, Satyen Harish Gohil, Nicholas R. Schindler, Lucas Pomerance, Laure Hirsch et al. · 2021 · Cancer Cell
- Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing dataDuanchen Sun, Xiangnan Guan, Amy E. Moran, Ling‐Yun Wu, David Z. Qian, Pepper S. Schedin, Mu‐Shui Dai, Alexey Valeryevich Danilov, Joshi J. Alumkal, Andrew Adey et al. · 2021 · Nature Biotechnology
- Co-option of Neutrophil Fates by Tissue EnvironmentsIván Ballesteros, Andrea Rubio-Ponce, Marco Genua, Eleonora Lusito, Immanuel Kwok, Gabriel F. Calvo, Tariq E. Khoyratty, Erinke van Grinsven, Sara González-Hernández, José Ángel Nicolás-Ávila et al. · 2020 · Cell
- Molecular characterization of selectively vulnerable neurons in Alzheimer’s diseaseLeng, Kun, Li, Emmy, Eser, Rana, Piergies, Antonia, Sit, Rene, Tan, Michelle, Neff, Norma, Li, Song Hua, Rodriguez, Roberta Diehl, Suemoto, Claudia Kimie et al. · 2021 · Nature Neuroscience
- Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progressionSujun Chen, Guanghui Zhu, Yue Yang, Fubo Wang, Yu‐Tian Xiao, Na Zhang, Xiaojie Bian, Yasheng Zhu, Yongwei Yu, Fei Liu et al. · 2021 · Nature Cell Biology
- MAFG-driven astrocytes promote CNS inflammationWheeler, Michael A., Clark, Iain C., Tjon, Emily C., Li, Zhaorong, Zandee, Stephanie E. J., Couturier, Charles P., Watson, Brianna R., Scalisi, Giulia, Alkwai, Sarah, Rothhammer, Veit et al. · 2020 · Nature
- Single-cell multiomic analysis identifies regulatory programs in mixed-phenotype acute leukemiaGranja, Jeffrey M., Klemm, Sandy, McGinnis, Lisa M., Kathiria, Arwa S., Mezger, Anja, Corces, M. Ryan, Parks, Benjamin, Gars, Eric, Liedtke, Michaela, Zheng, Grace X. Y. et al. · 2019 · Nature Biotechnology
- Physiological blood–brain transport is impaired with age by a shift in transcytosisYang, Andrew C., Stevens, Marc Y., Chen, Michelle B., Lee, Davis P., Stähli, Daniel, Gate, David, Contrepois, Kévin, Chen, Winnie, Iram, Tal, Zhang, Lichao et al. · 2020 · Nature
- Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathologyMathys, Hansruedi, Peng, Zhuyu, Boix, Carles A., Victor, Matheus B., Leary, Noelle, Babu, Sudhagar, Abdelhady, Ghada, Jiang, Xueqiao, Ng, Ayesha P., Ghafari, Kimia et al. · 2023 · Cell
- A single-cell atlas of the human healthy airwaysDeprez, Marie, Zaragosi, Laure-Emmanuelle, Truchi, Marin, Garcia, Sandra Ruiz, Arguel, Marie-Jeanne, Lebrigand, Kevin, Paquet, Agnès, Pee’r, Dana, Marquette, Charles-Hugo, Leroy, Sylvie et al. · 2019
- Developmental diversification of cortical inhibitory interneuronsMayer, Christian, Hafemeister, Christoph, Bandler, Rachel C., Machold, Robert, Batista Brito, Renata, Jaglin, Xavier, Allaway, Kathryn, Butler, Andrew, Fishell, Gord, Satija, Rahul · 2018 · Nature
- Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistanceYanshuo Chu, Enyu Dai, Yating Li, Guangchun Han, Guangsheng Pei, Davis R. Ingram, Krupa Thakkar, Jiang‐Jiang Qin, Minghao Dang, Xiuning Le et al. · 2023 · Nature Medicine