Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice

Chen, Y., Wang, L., Kang, Q., Zhang, X., Yu, G., Wan, X., Wang, J., & Zhu, K. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000477308 · Cited by 10,730 · see citing works

Exploring the full spectrum of macrophage activation

Mosser, D. M., & Edwards, J. P. (2008) · Nature Reviews Immunology · doi:10.1038/nri2448 · Cited by 9,144 · see citing works

Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice

Mizgerd, J. P., Kubo, H., Kutkoski, G. J., Bhagwan, S. D., Scharffetter-Kochanek, K., Beaudet, A. L., & Doerschuk, C. M. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.8.1357 · Cited by 7,332 · see citing works

The Inflammasome

Martinon, F., Burns, K., & Tschopp, J. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00599-3 · Cited by 6,066 · see citing works

Monocyte and macrophage heterogeneity

Gordon, S., & Taylor, P. R. (2005) · Nature Reviews Immunology · doi:10.1038/nri1733 · Cited by 5,190 · see citing works

Obesity induces a phenotypic switch in adipose tissue macrophage polarization

Lumeng, C. N., Bodzin, J. L., & Saltiel, A. R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci29881 · Cited by 4,664 · see citing works

Tumors: Wounds That Do Not Heal

Flier, J. S., Underhill, L. H., & Dvorak, H. F. (1986) · New England Journal of Medicine · doi:10.1056/nejm198612253152606 · Cited by 4,391 · see citing works

NF-κB regulation in the immune system

Li, Q., & Verma, I. M. (2002) · Nature Reviews Immunology · doi:10.1038/nri910 · Cited by 4,007 · see citing works

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

Biswas, S. K., & Mantovani, A. (2010) · Nature Immunology · doi:10.1038/ni.1937 · Cited by 3,840 · see citing works

Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TAN

Fridlender, Z. G., Sun, J., Kim, S., Kapoor, V., Cheng, G., Ling, L. E., Worthen, G. S., & Albelda, S. Μ. (2009) · Cancer Cell · doi:10.1016/j.ccr.2009.06.017 · Cited by 3,382 · see citing works

Development of Monocytes, Macrophages, and Dendritic Cells

Geissmann, F., Manz, M. G., Jung, S., Sieweke, M. H., Merad, M., & Ley, K. (2010) · Science · doi:10.1126/science.1178331 · Cited by 3,049 · see citing works

Neutrophils and immunity: challenges and opportunities

Nathan, C. (2006) · Nature reviews. Immunology · doi:10.1038/nri1785 · Cited by 2,971 · see citing works

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

Vandanmagsar, B., Youm, Y.-H., Ravussin, A., Galgani, J. E., Stadler, K., Mynatt, R. L., Ravussin, E., Stephens, J. M., & Dixit, V. D. (2011) · Nature Medicine · doi:10.1038/nm.2279 · Cited by 2,655 · see citing works

Nonresolving Inflammation

Nathan, C., & Ding, A. (2010) · Cell · doi:10.1016/j.cell.2010.02.029 · Cited by 2,183 · see citing works

Macrophage-specific PPARγ controls alternative activation and improves insulin resistance

Odegaard, J. I., Ricardo-Gonzalez, R. R., Goforth, M. H., Morel, C. R., Subramanian, V., Mukundan, L., Eagle, A. R., Vats, D., Brombacher, F., Ferrante, A. W., et al. (2007) · Nature · doi:10.1038/nature05894 · Cited by 2,107 · see citing works

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

Neill, D. R., Wong, S. H., Bellosi, A., Flynn, R. J., Daly, M. G., Langford, T. K. A., Bucks, C. M., Kane, C. M., Fallon, P. G., Pannell, R., et al. (2010) · Nature · doi:10.1038/nature08900 · Cited by 2,079 · see citing works

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

Moro, K., Yamada, T., Tanabe, M., Takeuchi, T., Ikawa, T., Kawamoto, H., Furusawa, J.-I., Ohtani, M., Fujii, H., & Koyasu, S. (2009) · Nature · doi:10.1038/nature08636 · Cited by 1,994 · see citing works

Fibrotic disease and the TH1/TH2 paradigm

Wynn, T. A. (2004) · Nature Reviews Immunology · doi:10.1038/nri1412 · Cited by 1,765 · see citing works

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

Ostrand‐Rosenberg, S., & Sinha, P. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0802740 · Cited by 1,733 · see citing works

Neutrophils, from marrow to microbes.

Borregaard, N. (2010) · Immunity · doi:10.1016/j.immuni.2010.11.011 · Cited by 1,550 · see citing works

Local macrophage proliferation, rather than recruitment from the blood, is a signature of Th2 inflammation

Jenkins, S., Ruckerl, D., Cook, P., Jones, L., Finkelman, F., van Rooijen, N., MacDonald, A., & Allen, J. (2011) · Science · doi:10.1126/science.1204351 · Cited by 1,427 · see citing works

Macrophages: master regulators of inflammation and fibrosis

Wynn, T., & Barron, L. (2010) · Seminars in Liver Disease · doi:10.1055/s-0030-1255354 · Cited by 1,392 · see citing works

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

Wu, D., Molofsky, A. B., Liang, H.-E., Ricardo-González, R. R., Jouihan, H. A., Bando, J. K., Chawla, A., & Locksley, R. M. (2011) · Science · doi:10.1126/science.1201475 · Cited by 1,361 · see citing works

Contribution of Neutrophils to Acute Lung Injury

Grommes, J., & Soehnlein, O. (2010) · Molecular Medicine · doi:10.2119/molmed.2010.00138 · Cited by 1,319 · see citing works

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

Krausgruber, T., Blazek, K. D., Smallie, T., Alzabin, S., Lockstone, H. E., Sahgal, N., Hussell, T., Feldmann, M., & Udalova, I. A. (2011) · Nature Immunology · doi:10.1038/ni.1990 · Cited by 1,296 · see citing works

Mast cells in the development of adaptive immune responses

Galli, S. J., Nakae, S., & Tsai, M. M. (2005) · Nature Immunology · doi:10.1038/ni1158 · Cited by 1,280 · see citing works

Human CD14dim Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

Cros, J. F., Cagnard, N., Woollard, K. J., Patey, N., Zhang, S., Sénéchal, B., Puel, A., Biswas, S. K., Moshous, D., Pïcard, C., et al. (2010) · Immunity · doi:10.1016/j.immuni.2010.08.012 · Cited by 1,251 · see citing works

Neutrophil kinetics in health and disease

Summers, C., Rankin, S. M., Condliffe, A. M., Singh, N., Peters, A. M., & Chilvers, E. R. (2010) · Trends in Immunology · doi:10.1016/j.it.2010.05.006 · Cited by 1,237 · see citing works

MAST CELLS AS “TUNABLE” EFFECTOR AND IMMUNOREGULATORY CELLS: Recent Advances

Galli, S. J., Kalesnikoff, J., Grimbaldeston, M. A., Piliponsky, A. M., Williams, C. M. M., & Tsai, M. M. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.21.120601.141025 · Cited by 1,231 · see citing works

Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes

Movahedi, K., Laoui, D., Gysemans, C. A., Baeten, M., Stangé, G. M., den Bossche, J. V., Mack, M., PIPELEERS, D. G., Veld, P. I. '., BAETSELIER, P. D., et al. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-4672 · Cited by 1,229 · see citing works

The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection

Satoh, T., Takeuchi, O., Vandenbon, A., Yasuda, K., Tanaka, Y., Kumagai, Y., Miyake, T., Matsushita, K., Okazaki, T., Saitoh, T., et al. (2010) · Nature Immunology · doi:10.1038/ni.1920 · Cited by 1,156 · see citing works

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

Sindrilaru, A., Peters, T., Wieschalka, S., Baican, C., Baican, A., Peter, H., Hainzl, A., Schatz, S., Qi, Y., Schlecht, A., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci44490 · Cited by 1,100 · see citing works

The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing

De Santa, F., Totaro, M. G., Prosperini, E., Notarbartolo, S., Testa, G., & Natoli, G. (2007) · Cell · doi:10.1016/j.cell.2007.08.019 · Cited by 965 · see citing works

Mast cell-orchestrated immunity to pathogens

Abraham, S. N., & John, A. L. S. (2010) · Nature reviews. Immunology · doi:10.1038/nri2782 · Cited by 959 · see citing works

Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine

Srivastava, M. K., Sinha, P., Clements, V. K., Rodrı́guez, P. C., & Ostrand‐Rosenberg, S. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-2587 · Cited by 954 · see citing works

Intestinal tolerance requires gut homing and expansion of FoxP3+ regulatory T cells in the lamina propria.

Hadis, U., Wahl, B., Schulz, O., Hardtke-Wolenski, M., Schippers, A., Wagner, N., Müller, W., Sparwasser, T., Förster, R., & Pabst, O. (2011) · Immunity · doi:10.1016/j.immuni.2011.01.016 · Cited by 893 · see citing works

Monocytes in atherosclerosis: subsets and functions

Woollard, K. J., & Geissmann, F. (2010) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2009.228 · Cited by 890 · see citing works

In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days

Pillay, J., den Braber, I., Vrisekoop, N., Kwast, L. M., de Boer, R. J., Borghans, J. A. M., Tesselaar, K., & Koenderman, L. (2010) · Blood · doi:10.1182/blood-2010-01-259028 · Cited by 873 · see citing works

CD4 + CD25 + Foxp3 + regulatory T cells induce alternative activation of human monocytes/macrophages

Tiemessen, M. M., Jagger, A. L., Evans, H. G., van Herwijnen, M. J. C., John, S., & Taams, L. S. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706832104 · Cited by 854 · see citing works

Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor

Marigo, I., Bosio, E., Solito, S., Mesa, C., Fernández, A., Dolcetti, L., Ugel, S., Sonda, N., Bicciato, S., Falisi, E., et al. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.010 · Cited by 854 · see citing works

The Terminology Issue for Myeloid-Derived Suppressor Cells

Gabrilovich, D. I., Bronte, V., Chen, S., Colombo, M. P., Ochoa, A. C., Ostrand‐Rosenberg, S., & Schreiber, H. W. (2007) · Cancer Research · doi:10.1158/0008-5472.can-06-3037 · Cited by 834 · see citing works

Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

Pesce, J. T., Ramalingam, T. R., Mentink-Kane, M. M., Wilson, M. S., El Kasmi, K. C., Smith, A. M., Thompson, R. W., Cheever, A. W., Murray, P. J., & Wynn, T. A. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000371 · Cited by 816 · see citing works

“Re-educating” tumor-associated macrophages by targeting NF-κB

Hagemann, T., Lawrence, T., McNeish, I., Charles, K. A., Kulbe, H., Thompson, R. G., Robinson, S. C., & Balkwill, F. R. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20080108 · Cited by 792 · see citing works

Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells

Corzo, C. A., Cotter, M. J., Cheng, P., Cheng, F., Kusmartsev, S. A., Sotomayor, E. M., Padhya, T. A., McCaffrey, T. V., McCaffrey, J. C., & Gabrilovich, D. I. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900092 · Cited by 765 · see citing works

Mast cells are essential intermediaries in regulatory T-cell tolerance

Lu, L.-F., Lind, E. F., Gondek, D. C., Bennett, K. A., Gleeson, M. W., Pino-Lagos, K., Scott, Z. A., Coyle, A. J., Reed, J. L., Van Snick, J., et al. (2006) · Nature · doi:10.1038/nature05010 · Cited by 751 · see citing works

New developments in mast cell biology

Kalesnikoff, J., & Galli, S. J. (2008) · Nature Immunology · doi:10.1038/ni.f.216 · Cited by 750 · see citing works

Immunomodulatory mast cells: negative, as well as positive, regulators of immunity

Galli, S. J., Grimbaldeston, M. A., & Tsai, M. M. (2008) · Nature reviews. Immunology · doi:10.1038/nri2327 · Cited by 738 · see citing works

Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent

Wilson, M. S., Madala, S. K., Ramalingam, T. R., Gochuico, B. R., Rosas, I. O., Cheever, A. W., & Wynn, T. A. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20092121 · Cited by 730 · see citing works

Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives

Rodrı́guez, P. C., & Ochoa, A. C. (2008) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00608.x · Cited by 722 · see citing works

Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo

Villadangos, J. A., & Schnorrer, P. (2007) · Nature reviews. Immunology · doi:10.1038/nri2103 · Cited by 695 · see citing works

MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsis

Delano, M. J., Scumpia, P. O., Weinstein, J. S., Coco, D. P., Nagaraj, S., Kelly‐Scumpia, K. M., O’Malley, K. A., Wynn, J. L., Antonenko, S. V., Al‐Quran, S. Z., et al. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20062602 · Cited by 656 · see citing works

Alternative macrophage activation and metabolism

Odegaard, J. I., & Chawla, A. (2011) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-011110-130138 · Cited by 640 · see citing works

Regulation of mast-cell and basophil function and survival by IgE

Kawakami, T., & Galli, S. J. (2002) · Nature reviews. Immunology · doi:10.1038/nri914 · Cited by 632 · see citing works

Role of mast cells in allergic and non-allergic immune responses: comparison of human and murine data

Bischoff, S. C. (2007) · Nature reviews. Immunology · doi:10.1038/nri2018 · Cited by 620 · see citing works

Obstacles and opportunities for understanding macrophage polarization

Murray, P. J., & Wynn, T. A. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.0710409 · Cited by 565 · see citing works

Heterogeneity and plasticity of T helper cells

Zhu, J., & Paul, W. E. (2009) · Cell Research · doi:10.1038/cr.2009.138 · Cited by 564 · see citing works

Peripheral B cell subsets

Allman, D., & Pillai, S. (2008) · Current Opinion in Immunology · doi:10.1016/j.coi.2008.03.014 · Cited by 536 · see citing works

Unravelling mononuclear phagocyte heterogeneity

Geissmann, F., Gordon, S., Hume, D. A., Mowat, A. M., & Randolph, G. J. (2010) · Nature reviews. Immunology · doi:10.1038/nri2784 · Cited by 529 · see citing works

Memory TH2 cells induce alternatively activated macrophages to mediate protection against nematode parasites

Anthony, R. M., Urban, J. F., Alem, F., Hamed, H. A., Rozo, C. T., Boucher, J.-L., Van Rooijen, N., & Gause, W. C. (2006) · Nature Medicine · doi:10.1038/nm1451 · Cited by 522 · see citing works

Anti-Inflammatory and Proresolving Lipid Mediators

Serhan, C. N., Yacoubian, S., & Yang, R. (2008) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev.pathmechdis.3.121806.151409 · Cited by 511 · see citing works

Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development

Doulatov, S. R., Notta, F., Eppert, K., Nguyen, L. T., Ohashi, P. S., & Dick, J. E. (2010) · Nature Immunology · doi:10.1038/ni.1889 · Cited by 510 · see citing works

Epigenetic regulation of the alternatively activated macrophage phenotype

Ishii, M., Wen, H., Corsa, C. A. S., Liu, T., Coelho, A. L., Allen, R., Carson, W. F., Cavassani, K. A., Li, X., Lukacs, N. W., et al. (2009) · Blood · doi:10.1182/blood-2009-04-217620 · Cited by 496 · see citing works

Mast cell–derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B

Grimbaldeston, M. A., Nakae, S., Kalesnikoff, J., Tsai, M. M., & Galli, S. J. (2007) · Nature Immunology · doi:10.1038/ni1503 · Cited by 486 · see citing works

Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice

Kawanishi, N., Yano, H., Yokogawa, Y., & Suzuki, K. (2026) · PubMed · doi:10.22029/eir.2010.1655 · Cited by 456 · see citing works

Mast Cells Are Key Promoters of Contact Allergy that Mediate the Adjuvant Effects of Haptens

Dudeck, A., Dudeck, J., Scholten, J., Petzold, A., Surianarayanan, S., Köhler, A., Peschke, K., Voehringer, D., Waskow, C., Krieg, T. M., et al. (2011) · Immunity · doi:10.1016/j.immuni.2011.03.028 · Cited by 455 · see citing works

Mast cell tryptases and chymases in inflammation and host defense.

Caughey, G. H. (2007) · Immunological Reviews · doi:10.1111/j.1600-065x.2007.00509.x · Cited by 442 · see citing works

TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

Verstrepen, L., Bekaert, T., Chau, T., Tavernier, J. H., Chariot, A., & Beyaert, R. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8064-8 · Cited by 440 · see citing works

C/EBPβ is required for 'emergency' granulopoiesis

Hirai, H., Zhang, P., Dayaram, T., Hetherington, C. J., Mizuno, S.-I., Imanishi, J., Akashi, K., & Tenen, D. G. (2006) · Nature Immunology · doi:10.1038/ni1354 · Cited by 425 · see citing works

TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells

Krutzik, S. R., Tan, B. H., Li, H., Ochoa, M. T., Liu, P. T., Sharfstein, S. E., Graeber, T. G., Sieling, P. A., Liu, Y.-J., Rea, T. H., et al. (2005) · Nature Medicine · doi:10.1038/nm1246 · Cited by 404 · see citing works

Mast cells in allergy and infection: versatile effector and regulatory cells in innate and adaptive immunity

Galli, S. J., & Tsai, M. (2010) · European Journal of Immunology · doi:10.1002/eji.201040559 · Cited by 403 · see citing works

Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease

Smith, A. M., Rahman, F. Z., Hayee, B., Graham, S. J., Marks, D. J., Sewell, G. W., Palmer, C. D., Wilde, J. I., Foxwell, B. M. J., Gloger, I., et al. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20091233 · Cited by 399 · see citing works

Granulocyte colony-stimulating factor: Molecular mechanisms of action during steady state and ‘emergency’ hematopoiesis

Panopoulos, A. D., & Watowich, S. S. (2008) · Cytokine · doi:10.1016/j.cyto.2008.03.002 · Cited by 396 · see citing works

Mast Cells Can Enhance Resistance to Snake and Honeybee Venoms

Metz, M., Piliponsky, A. M., Chen, C., Lammel, V., Åbrink, M., Pejler, G., Tsai, M. M., & Galli, S. J. (2006) · Science · doi:10.1126/science.1128877 · Cited by 381 · see citing works

Hypoxia-Inducible Factors as Essential Regulators of Inflammation

Imtiyaz, H. Z., & Simon, M. C. (2010) · Current Topics in Microbiology and Immunology · doi:10.1007/82_2010_74 · Cited by 379 · see citing works

Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice

Sawanobori, Y., Ueha, S., Kurachi, M., Shimaoka, T., Talmadge, J. E., Abe, J., Shono, Y., Kitabatake, M., Kakimi, K., Mukaida, N., et al. (2008) · Blood · doi:10.1182/blood-2008-01-136895 · Cited by 367 · see citing works

Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow

Ueda, Y., Kondo, M., & Kelsoe, G. H. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20041419 · Cited by 343 · see citing works

The IL-21 receptor augments Th2 effector function and alternative macrophage activation

Pesce, J. T. (2006) · Journal of Clinical Investigation · doi:10.1172/jci27727 · Cited by 340 · see citing works

A Paradoxical Role for Myeloid-Derived Suppressor Cells in Sepsis and Trauma

Cuenca, A. G., Delano, M. J., Kelly‐Scumpia, K. M., Moreno, C. R. D. C., Scumpia, P. O., LaFace, D., Heyworth, P. G., Efron, P. A., & Moldawer, L. L. (2010) · Molecular Medicine · doi:10.2119/molmed.2010.00178 · Cited by 340 · see citing works

Hematopoietic Stem and Progenitor Cells: Clinical and Preclinical Regeneration of the Hematolymphoid System

Shizuru, J. A., Negrin, R. S., & Weissman, I. L. (2002) · Annual Review of Medicine · doi:10.1146/annurev.med.54.101601.152334 · Cited by 337 · see citing works

Designing Vaccines Based on Biology of Human Dendritic Cell Subsets

Palucka, K., Banchereau, J., & Mellman, I. (2010) · Immunity · doi:10.1016/j.immuni.2010.10.007 · Cited by 330 · see citing works

Cutting Edge: Stat6-Dependent Substrate Depletion Regulates Nitric Oxide Production

Rutschman, R. L., Lang, R., Hesse, M., Ihle, J. N., Wynn, T. A., & Murray, P. J. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.4.2173 · Cited by 324 · see citing works

Mast Cell Proteases

Pejler, G., Åbrink, M., Ringvall, M., & Wernersson, S. (2007) · Advances in immunology · doi:10.1016/s0065-2776(07)95006-3 · Cited by 324 · see citing works

IL‐1β regulates a novel myeloid‐derived suppressor cell subset that impairs NK cell development and function

Elkabets, M., Ribeiro, V. S. G., Dinarello, C. A., Ostrand‐Rosenberg, S., Santo, J. P. D., Apte, R. N., & Vosshenrich, C. A. J. (2010) · European Journal of Immunology · doi:10.1002/eji.201041037 · Cited by 319 · see citing works

The ins and outs of IgE-dependent mast-cell exocytosis

Blank, U., & Rivera, J. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.03.005 · Cited by 313 · see citing works

Tumor-Associated CD8+ T Cell Tolerance Induced by Bone Marrow-Derived Immature Myeloid Cells

Kusmartsev, S. A., Nagaraj, S., & Gabrilovich, D. I. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.7.4583 · Cited by 310 · see citing works

Mast cells promote homeostasis by limiting endothelin-1-induced toxicity

Maurer, M., Wedemeyer, J., Metz, M., Piliponsky, A. M., Weller, K., Chatterjea, D., Clouthier, D. E., Yanagisawa, M., Tsai, M. M., & Galli, S. J. (2004) · Nature · doi:10.1038/nature03085 · Cited by 303 · see citing works

Coculture of interleukin 3-dependent mouse mast cells with fibroblasts results in a phenotypic change of the mast cells.

Levi‐Schaffer, F., Austen, K. F., Gravallese, P. M., & Stevens, R. L. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.17.6485 · Cited by 284 · see citing works

Turning straw into gold: directing cell fate for regenerative medicine

Cohen, D. E., & Melton, D. (2011) · Nature reviews genetics · doi:10.1038/nrg2938 · Cited by 283 · see citing works

Epigenetic Instability of Cytokine and Transcription Factor Gene Loci Underlies Plasticity of the T Helper 17 Cell Lineage

Mukasa, R., Balasubramani, A., Lee, Y. K., Whitley, S. K., Weaver, B. T., Shibata, Y., Crawford, G. E., Hatton, R. D., & Weaver, C. T. (2010) · Immunity · doi:10.1016/j.immuni.2010.04.016 · Cited by 270 · see citing works

Mast cells and eicosanoid mediators: a system of reciprocal paracrine and autocrine regulation

Boyce, J. A. (2007) · Immunological Reviews · doi:10.1111/j.1600-065x.2007.00512.x · Cited by 255 · see citing works

Type I IFN Signaling Is Crucial for Host Resistance against Different Species of Pathogenic Bacteria

Mancuso, G., Midiri, A., Biondo, C., Beninati, C., Zummo, S., Galbo, R., Tomasello, F. F., Gambuzza, M. E., Macrì, G., Ruggeri, A., et al. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.5.3126 · Cited by 248 · see citing works

IgE enhances Fc epsilon receptor I expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells: synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and mediator release.

Yamaguchi, M., Sayama, K., Yano, K., Lantz, C. S., Noben-Trauth, N., Ra, C., Costa, J. J., & Galli, S. J. (1999) · PubMed · Cited by 246 · see citing works

Regulation of pathogenesis and immunity in helminth infections

Maizels, R. M., Pearce, E. J., Artis, D., Yazdanbakhsh, M., & Wynn, T. A. (2009) · The Journal of Experimental Medicine · doi:10.1084/jem.20091903 · Cited by 242 · see citing works

STAT3 controls myeloid progenitor growth during emergency granulopoiesis

Zhang, H., Nguyen-Jackson, H., Panopoulos, A. D., Li, H. S., Murray, P. J., & Watowich, S. S. (2010) · Blood · doi:10.1182/blood-2009-12-259630 · Cited by 232 · see citing works

The Transcriptional Activation Program of Human Neutrophils in Skin Lesions Supports Their Important Role in Wound Healing

Theilgaard‐Mönch, K., Knudsen, S., Follin, P., & Borregaard, N. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.12.7684 · Cited by 226 · see citing works

Mast cells that reside at different locations in the jejunum of mice infected with Trichinella spiralis exhibit sequential changes in their granule ultrastructure and chymase phenotype.

Friend, D. S., Ghildyal, N., Austen, K. F., Gurish, M. F., Matsumoto, R., & Stevens, R. L. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.135.1.279 · Cited by 224 · see citing works

IgE Enhances Fcε Receptor I Expression and IgE-Dependent Release of Histamine and Lipid Mediators from Human Umbilical Cord Blood-Derived Mast Cells: Synergistic Effect of IL-4 and IgE on Human Mast Cell Fcε Receptor I Expression and Mediator Release

Yamaguchi, M., Sayama, K., Yano, K., Lantz, C. S., Noben-Trauth, N., Ra, C., Costa, J. J., & Galli, S. J. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.9.5455 · Cited by 222 · see citing works

Signal transduction pathways and transcriptional regulation in Th17 cell differentiation

Hirahara, K., Ghoreschi, K., Laurence, A. D. J., Yang, X., Kanno, Y., & O’Shea, J. J. (2010) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2010.10.006 · Cited by 217 · see citing works

Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages

London, A., Itskovich, E., Benhar, I., Kalchenko, V., Mack, M., Jung, S., & Schwartz, M. (2011) · The Journal of Experimental Medicine · doi:10.1084/jem.20101202 · Cited by 213 · see citing works

The Master Switch: The Role of Mast Cells in Autoimmunity and Tolerance

Sayed, B. A., Christy, A. L., Quirion, M. R., & Brown, M. A. (2008) · Annual Review of Immunology · doi:10.1146/annurev.immunol.26.021607.090320 · Cited by 207 · see citing works

Epigenetic regulation of immune cell functions during post-septic immunosuppression

Carson, W. F., Cavassani, K. A., Dou, Y., & Kunkel, S. L. (2011) · Epigenetics · doi:10.4161/epi.6.3.14017 · Cited by 205 · see citing works

PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis

Uutela, M., Wirzenius, M., Paavonen, K., et al. (2004) · Blood · doi:10.1182/blood-2004-04-1485 · Cited by 198 · see citing works

CCL2 Blockade Augments Cancer Immunotherapy

Fridlender, Z. G., Buchlis, G., Kapoor, V., Cheng, G., Sun, J., Singhal, S. K., Crisanti, M. C., Wang, L. S., Heitjan, D. F., Snyder, L. A., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-2326 · Cited by 193 · see citing works

Immune Sensitization in the Skin Is Enhanced by Antigen-Independent Effects of IgE

Bryce, P. J., Miller, M. L., Miyajima, I., Tsai, M. M., Galli, S. J., & Oettgen, H. C. (2004) · Immunity · doi:10.1016/s1074-7613(04)00080-9 · Cited by 183 · see citing works

The Mast Cell-restricted Tryptase mMCP-6 Has a Critical Immunoprotective Role in Bacterial Infections

Thakurdas, S. M., Melicoff, E., Sansores-García, L., Moreira, D. C., Petrova, Y., Stevens, R. L., & Adachi, R. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m611842200 · Cited by 183 · see citing works

Effect of recombinant human IL-4 on tryptase, chymase, and Fc epsilon receptor type I expression in recombinant human stem cell factor-dependent fetal liver-derived human mast cells

Xia, H.-Z., Du, Z., Craig, S. S., Klisch, G., Noben-Trauth, N., Kochan, J. P., Huff, T., Irani, A. M., & Schwartz, L. B. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.159.6.2911 · Cited by 159 · see citing works

Molecular mechanism of mast cell–mediated innate defense against endothelin and snake venom sarafotoxin

Schneider, L. A., Schlenner, S., Feyerabend, T. B., Wunderlin, M., & Rodewald, H.-R. (2007) · The Journal of Experimental Medicine · doi:10.1084/jem.20071262 · Cited by 157 · see citing works

Interleukin-4 Promotes the Development of Tryptase and Chymase Double-Positive Human Mast Cells Accompanied by Cell Maturation

Toru, H., Eguchi, M., Matsumoto, R., Yanagida, M., Yata, J., & Nakahata, T. (1998) · Blood · doi:10.1182/blood.v91.1.187 · Cited by 151 · see citing works

The Myeloid Transcription Factor KLF2 Regulates the Host Response to Polymicrobial Infection and Endotoxic Shock

Mahabeleshwar, G. H., Kawanami, D., Sharma, N., Takami, Y., Zhou, G., Shi, H., Nayak, L. V., Jeyaraj, D., Grealy, R., White, M., et al. (2011) · Immunity · doi:10.1016/j.immuni.2011.04.014 · Cited by 149 · see citing works

c-Kit Ligand Mediates Increased Expression of Cytosolic Phospholipase A2, Prostaglandin Endoperoxide Synthase-1, and Hematopoietic Prostaglandin D2 Synthase and Increased IgE-dependent Prostaglandin D2 Generation in Immature Mouse Mast Cells

Murakami, M., Matsumoto, R., Urade, Y., Austen, K. F., & Arm, J. P. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.7.3239 · Cited by 148 · see citing works

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

Akahoshi, M., Song, C. H., Piliponsky, A. M., Metz, M., Guzzetta, A. W., Åbrink, M., Schlenner, S., Feyerabend, T. B., Rodewald, H.-R., Pejler, G., et al. (2011) · Journal of Clinical Investigation · doi:10.1172/jci46139 · Cited by 146 · see citing works

Protease–proteoglycan complexes of mouse and human mast cells and importance of their β‐tryptase–heparin complexes in inflammation and innate immunity

Stevens, R. L., & Adachi, R. (2007) · Immunological Reviews · doi:10.1111/j.1600-065x.2007.00525.x · Cited by 145 · see citing works

Mast Cell-Derived TNF Can Exacerbate Mortality during Severe Bacterial Infections in C57BL/6-Kit Mice

Piliponsky, A. M., Chen, C., Grimbaldeston, M. A., Burns, S. M., Hardy, J. W., Kalesnikoff, J., Contag, C. H., Tsai, M. M., & Galli, S. J. (2009) · American Journal Of Pathology · doi:10.2353/ajpath.2010.090342 · Cited by 142 · see citing works

Alternatively Activated Macrophages Elicited by Helminth Infection Can Be Reprogrammed to Enable Microbial Killing

Mylonas, K. J., Nair, M. G., Prieto-Lafuente, L., Paape, D., & Allen, J. E. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803463 · Cited by 140 · see citing works

IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia

Ueda, Y., Cain, D. W., Kuraoka, M., Kondo, M., & Kelsoe, G. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803961 · Cited by 138 · see citing works

NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils

von Vietinghoff, S., Lättig-Tünnemann, G., Eulenberg, C., et al. (2007) · Blood · doi:10.1182/blood-2006-10-055327 · Cited by 133 · see citing works

Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis

Piliponsky, A. M., Chen, C., Nishimura, T., Metz, M., Rios, E. J., Dobner, P. R., Wada, E., Wada, K., Zacharias, S., Mohanasundaram, U. M., et al. (2008) · Nature Medicine · doi:10.1038/nm1738 · Cited by 132 · see citing works

Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10

Kelly‐Scumpia, K. M., Scumpia, P. O., Delano, M. J., Weinstein, J. S., Cuenca, A. G., Wynn, J. L., & Moldawer, L. L. (2010) · The Journal of Experimental Medicine · doi:10.1084/jem.20091959 · Cited by 132 · see citing works

SHIP Represses the Generation of IL-3-Induced M2 Macrophages by Inhibiting IL-4 Production from Basophils

Kuroda, E., Ho, V. W., Rüschmann, J., Antignano, F., Hamilton, M. J., Rauh, M. J., Antov, A., Flavell, R. A., Sly, L. M., & Krystal, G. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900864 · Cited by 131 · see citing works

The Role of Polyamines in Supporting Growth of Mammalian Cells Is Mediated through Their Requirement for Translation Initiation and Elongation

Landau, G., Bercovich, Z., Park, M. H., & Kahana, C. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.106419 · Cited by 130 · see citing works

Cutting Edge: Bacterial Infection Induces Hematopoietic Stem and Progenitor Cell Expansion in the Absence of TLR Signaling

Scumpia, P. O., Kelly‐Scumpia, K. M., Delano, M. J., Weinstein, J. S., Cuenca, A. G., Al‐Quran, S. Z., Bovio, I. M., Akira, S., Kumagai, Y., & Moldawer, L. L. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0903652 · Cited by 129 · see citing works

Identification of CD66a and CD66b as the Major Galectin-3 Receptor Candidates in Human Neutrophils

Feuk‐Lagerstedt, E., Jordan, E. T., Leffler, H., Dahlgren, C., & Karlsson, A. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.10.5592 · Cited by 127 · see citing works

Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma

Yu, M., Eckart, M. R., Morgan, A. A., Mukai, K., Butte, A. J., Tsai, M. M., & Galli, S. J. (2011) · Journal of Clinical Investigation · doi:10.1172/jci43598 · Cited by 126 · see citing works

Expression profiles of angiogenic growth factors in squamous cell carcinomas of the head and neck

Ninck, S., Reisser, C., Dyckhoff, G., et al. (2003) · International Journal of Cancer · doi:10.1002/ijc.11188 · Cited by 126 · see citing works

Complement Receptor Mac-1 Is an Adaptor for NB1 (CD177)-mediated PR3-ANCA Neutrophil Activation

Jerke, U., Rolle, S., Dittmar, G., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.171256 · Cited by 106 · see citing works

Further characterization of the NB 1 antigen as a variably expressed 56–62 kD GPI‐linked glycoprotein of plasma membranes and specific granules of neutrophils

Goldschmeding, R., van Dalen, C. M., Faber, N., et al. (1992) · British Journal of Haematology · doi:10.1111/j.1365-2141.1992.tb08237.x · Cited by 105 · see citing works

Mast Cell Homeostasis: A Fundamental Aspect of Allergic Disease

Ryan, J. J., Kashyap, M., Bailey, D., Kennedy, S., Speiran, K., Brenzovich, J., Barnstein, B. O., Oskeritzian, C. A., & Gomez, G. (2007) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.v27.i1.20 · Cited by 86 · see citing works

Macrophages and cancer

Nardin, A. (2008) · Frontiers in bioscience · doi:10.2741/2944 · Cited by 79 · see citing works

Growth, phenotype, and function of human intestinal mast cells are tightly regulated by transforming growth factor β1

Gebhardt, T., Lorentz, A., Detmer, F., Trautwein, C., Bektas, H., Manns, M. P., & Bischoff, S. C. (2005) · Gut · doi:10.1136/gut.2004.054650 · Cited by 78 · see citing works

Mast cells as regulators of adaptive immunity to tumours

Wasiuk, A., de Vries, V. C., Hartmann, K., Roers, A., & Noelle, R. J. (2008) · Clinical & Experimental Immunology · doi:10.1111/j.1365-2249.2008.03840.x · Cited by 78 · see citing works

Biological fate and clinical implications of arginine metabolism in tissue healing

Curran, J. N., Winter, D. C., & Bouchier-Hayes, D. (2006) · Wound Repair and Regeneration · doi:10.1111/j.1743-6109.2006.00151.x · Cited by 76 · see citing works

Tryptase and chymase, markers of distinct types of human mast cells

Craig, S. S., & Schwartz, L. B. (1989) · Immunologic Research · doi:10.1007/bf02919075 · Cited by 74 · see citing works

Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells

Kanakura, Y., Thompson, H., Nakano, T., et al. (1988) · Blood · doi:10.1182/blood.v72.3.877.877 · Cited by 70 · see citing works

Multiple bidirectional alterations of phenotype and changes in proliferative potential during the in vitro and in vivo passage of clonal mast cell populations derived from mouse peritoneal mast cells

Kanakura, Y., Thompson, H., Nakano, T., et al. (1988) · Blood · doi:10.1182/blood.v72.3.877.bloodjournal723877 · Cited by 65 · see citing works

Regulation of chymase production in human mast cell progenitors

Ahn, K., Takai, S., Pawankar, R., Kuramasu, A., Ohtsu, H., Kempuraj, D., Tomita, H., Iida, M., Matsumoto, K., Akasawa, A., et al. (2000) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2000.108107 · Cited by 63 · see citing works

Carcinoembryonic Antigen-Related Cell Adhesion Molecule-1 Regulates Granulopoiesis by Inhibition of Granulocyte Colony-Stimulating Factor Receptor

Pan, H., & Shively, J. E. (2010) · Immunity · doi:10.1016/j.immuni.2010.10.009 · Cited by 60 · see citing works

Epigenetic reprogramming of the RORC locus during in vitro expansion is a distinctive feature of human memory but not naïve Treg

Schmidl, C., Hansmann, L., Andreesen, R., Edinger, M., Hoffmann, P., & Rehli, M. (2011) · European Journal of Immunology · doi:10.1002/eji.201041067 · Cited by 59 · see citing works

Lack of NB1 GP (CD177/HNA-2a) gene transcription in NB1 GP- neutrophils from NB1 GP–expressing individuals and association of low expression with NB1 gene polymorphisms

Wolff, J., Brendel, C. A., Fink, L., et al. (2003) · Blood · doi:10.1182/blood-2002-09-2831 · Cited by 58 · see citing works

Effect of lipopolysaccharide (LPS) and peptidoglycan (PGN) on human mast cell numbers, cytokine production, and protease composition

Kirshenbaum, A. S., Swindle, E. J., Kulka, M., et al. (2008) · BMC Immunology · doi:10.1186/1471-2172-9-45 · Cited by 57 · see citing works

B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase

Johnson, B. A., Kahler, D. J., Baban, B., Chandler, P., Kang, B., Shimoda, M., Koni, P. A., Pihkala, J. P. S., Vilagos, B., Busslinger, M., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914347107 · Cited by 48 · see citing works

Mast Cells Regulate the Magnitude and the Cytokine Microenvironment of the Contact Hypersensitivity Response

Norman, M. U., Hwang, J. H., Hulliger, S., et al. (2008) · American Journal Of Pathology · doi:10.2353/ajpath.2008.070559 · Cited by 45 · see citing works

Human neutrophil alloantigens systems

Moritz, E., Norcia, A. M. M. I., Cardone, J. D. B., et al. (2009) · Anais da Academia Brasileira de Ciências · doi:10.1590/s0001-37652009000300019 · Cited by 37 · see citing works

Nuclear phospholipid scramblase 1 prolongs the mitotic expansion of granulocyte precursors during G-CSF-induced granulopoiesis

Chen, C.-W. D., Sowden, M. P., Zhao, Q., Wiedmer, T., & Sims, P. J. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.0111006 · Cited by 29 · see citing works

Normal human granulopoiesis revisited. II. Bone marrow data.

Jy, M. (1985) · PubMed · Cited by 25 · see citing works

Neutrophil recruitment and function in health and inflammation

Kolaczkowska, E., & Kubes, P. (2013) · Nature Reviews Immunology · doi:10.1038/nri3399 · Cited by 5,472 · see citing works

Macrophage plasticity, polarization, and function in health and disease

Shapouri‐Moghaddam, A., Mohammadian, S., Vazini, H., Taghadosi, M., Esmaeili, S., Mardani, F., Seifi, B., Mohammadi, A., Afshari, J. T., & Sahebkar, A. (2018) · Journal of Cellular Physiology · doi:10.1002/jcp.26429 · Cited by 4,930 · see citing works

Macrophages in Tissue Repair, Regeneration, and Fibrosis

Wynn, T. A., & Vannella, K. M. (2016) · Immunity · doi:10.1016/j.immuni.2016.02.015 · Cited by 4,481 · see citing works

Transition from inflammation to proliferation: a critical step during wound healing

Landén, N. X., Li, D., & Ståhle, M. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2268-0 · Cited by 1,980 · see citing works

The role of myeloid cells in cancer therapies

Engblom, C., Pfirschke, C., & Pittet, M. J. (2016) · Nature Reviews Cancer · doi:10.1038/nrc.2016.54 · Cited by 788 · see citing works

Satellite Cells and Skeletal Muscle Regeneration

Dumont, N. A., Bentzinger, C. F., Sincennes, M., & Rudnicki, M. A. (2015) · Comprehensive Physiology · doi:10.1002/cphy.c140068 · Cited by 719 · see citing works

Neutrophil cell surface receptors and their intracellular signal transduction pathways

Futosi, K., Fodor, S., & Mócsai, A. (2013) · International Immunopharmacology · doi:10.1016/j.intimp.2013.06.034 · Cited by 642 · see citing works

Immunology of Wound Healing

Ellis, S., Lin, E. J., & Tartar, D. (2018) · Current Dermatology Reports · doi:10.1007/s13671-018-0234-9 · Cited by 625 · see citing works

Mast Cells, Mastocytosis, and Related Disorders

Theoharides, T. C., Valent, P., & Akin, C. (2015) · New England Journal of Medicine · doi:10.1056/nejmra1409760 · Cited by 518 · see citing works

Macrophage functional polarization (M1/M2) in response to varying fiber and pore dimensions of electrospun scaffolds

Garg, K., Pullen, N. A., Oskeritzian, C. A., Ryan, J. J., & Bowlin, G. L. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.02.065 · Cited by 457 · see citing works

Cellular dynamics in the muscle satellite cell niche

Bentzinger, C. F., Wang, Y. X., Dumont, N. A., & Rudnicki, M. A. (2013) · The EMBO Reports · doi:10.1038/embor.2013.182 · Cited by 398 · see citing works

Redox control of inflammation in macrophages

Brüne, B., Dehne, N., Grossmann, N., Jung, M., Namgaladze, D., Schmid, T., von Knethen, A., & Weigert, A. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4785 · Cited by 377 · see citing works

The Adenosine-Dependent Angiogenic Switch of Macrophages to an M2-Like Phenotype is Independent of Interleukin-4 Receptor Alpha (IL-4Rα) Signaling

Ferrante, C. J., Pinhal-Enfield, G., Elson, G., Cronstein, B. N., Hasko, G., Outram, S., & Leibovich, S. J. (2013) · Inflammation · doi:10.1007/s10753-013-9621-3 · Cited by 375 · see citing works

Metal Drugs and the Anticancer Immune Response

Englinger, B., Pirker, C., Heffeter, P., Terenzi, A., Kowol, C. R., Keppler, B. K., & Berger, W. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00396 · Cited by 355 · see citing works

Adipose tissue-resident immune cells: key players in immunometabolism

Schipper, H. S., Prakken, B., Kalkhoven, E., & Boes, M. (2012) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2012.05.011 · Cited by 342 · see citing works

Macrophage reaction against biomaterials in the mouse model–phenotypes, functions and markers

Klopfleisch, R. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.07.003 · Cited by 298 · see citing works

Contrasting phagosome pH regulation and Maturation in Human M1 and M2 macrophages

Canton, J., Khezri, R., Glogauer, M., & Grinstein, S. (2014) · Molecular Biology of the Cell · doi:10.1091/mbc.e14-05-0967 · Cited by 221 · see citing works

Disclosure of the culprits: macrophages-versatile regulators of wound healing.

Sindrilaru, A., & Scharffetter-Kochanek, K. (2013) · Advances in Wound Care · doi:10.1089/wound.2012.0407 · Cited by 223 · see citing works

Substrate stiffness modulates bone marrow-derived macrophage polarization through NF-κB signaling pathway

Chen, M., Zhang, Y., Zhou, P., Liu, X., Zhao, H., Zhou, X., Gu, Q., Li, B., Zhu, X., & Shi, Q. (2020) · Bioactive Materials · doi:10.1016/j.bioactmat.2020.05.004 · Cited by 229 · see citing works

Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis

Vannella, K. M., Ramalingam, T. R., Borthwick, L. A., Barron, L., Hart, K. M., Thompson, R. W., Kindrachuk, K. N., Cheever, A. W., White, S., Budelsky, A. L., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aaf1938 · Cited by 188 · see citing works

Hypoxia-inducible factors: key regulators of myeloid cells during inflammation

Lin, N., & Simon, M. C. (2016) · Journal of Clinical Investigation · doi:10.1172/jci84426 · Cited by 170 · see citing works

MicroRNA 21 Is a Homeostatic Regulator of Macrophage Polarization and Prevents Prostaglandin E2-Mediated M2 Generation

Wang, Z., Brandt, S., Medeiros, A., Wang, S., Wu, H., Dent, A., & Serezani, C. H. (2015) · PLOS ONE · doi:10.1371/journal.pone.0115855 · Cited by 169 · see citing works

Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging

Säwen, P., Eldeeb, M., Erlandsson, E., Kristiansen, T. A., Laterza, C., Kokaia, Z., Karlsson, G., Yuan, J., Soneji, S., Mandal, P. K., et al. (2018) · eLife · doi:10.7554/elife.41258 · Cited by 120 · see citing works

Immune cells in the retina and choroid: Two different tissue environments that require different defenses and surveillance

McMenamin, P. G., Saban, D. R., & Dando, S. J. (2019) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2018.12.002 · Cited by 115 · see citing works

Mast cell disorders in Ehlers-Danlos syndrome

Seneviratne, S. L., Maitland, A., & Afrin, L. (2017) · American Journal of Medical Genetics Part C: Seminars in Medical Genetics · doi:10.1002/ajmg.c.31555 · Cited by 107 · see citing works

DFMO and 5-azacytidine increase M1 macrophages in the tumor microenvironment of murine ovarian cancer

Travers, M., Brown, S. M., Dunworth, M., Holbert, C. E., Wiehagen, K. R., Bachman, K. E., Foley, J. R., Stone, M. L., Baylin, S. B., Casero, R. A., et al. (2019) · Cancer Research · doi:10.1158/0008-5472.can-18-4018 · Cited by 103 · see citing works

ES-62, a therapeutic anti-inflammatory agent evolved by the filarial nematode Acanthocheilonema viteae

Pineda, M. A., Lumb, F., Harnett, M. M., & Harnett, W. (2014) · Molecular and Biochemical Parasitology · doi:10.1016/j.molbiopara.2014.03.003 · Cited by 88 · see citing works

Targeting epigenetically maladapted vascular niche alleviates liver fibrosis in nonalcoholic steatohepatitis

Zhang, H., Ma, Y., Cheng, X., Wu, D., Huang, X., Chen, B., Ren, Y., Jiang, W., Tang, X., Bai, T., et al. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abd1206 · Cited by 65 · see citing works

Hemp (Cannabis sativa L.) Protein Hydrolysates Promote Anti-Inflammatory Response in Primary Human Monocytes

Rodriguez-Martin, N. M., Montserrat-de la Paz, S., Toscano, R., Grao-Cruces, E., Villanueva, A., Pedroche, J., Millan, F., & Millan-Linares, M. C. (2020) · Biomolecules · doi:10.3390/biom10050803 · Cited by 61 · see citing works

Genetic Regulation of Tryptase Production and Clinical Impact: Hereditary Alpha Tryptasemia, Mastocytosis and Beyond

Sprinzl, B., Greiner, G., Uyanik, G., Arock, M., Haferlach, T., Sperr, W. R., Valent, P., & Hoermann, G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22052458 · Cited by 51 · see citing works

Association of Postural Tachycardia Syndrome and Ehlers-Danlos Syndrome with Mast Cell Activation Disorders

Bonamichi-Santos, R., Yoshimi-Kanamori, K., Giavina-Bianchi, P., & Aun, M. V. (2018) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2018.04.004 · Cited by 42 · see citing works

Tissue Biology: In Search of a New Paradigm

Adler, M., Chavan, A. R., & Medzhitov, R. (2023) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-120420-113830 · Cited by 40 · see citing works

Meningeal mast cells as key effectors of stroke pathology.

Arac, A., Grimbaldeston, M. A., Galli, S. J., Bliss, T. M., & Steinberg, G. K. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00126 · Cited by 37 · see citing works

The versatile plasmacytoid dendritic cell: Function, heterogeneity, and plasticity

(2019) · International Review of Cell and Molecular Biology · doi:10.1016/bs.ircmb.2019.10.002 · Cited by 35 · see citing works

MKP-1 coordinates ordered macrophage-phenotype transitions essential for stem cell-dependent tissue repair

Perdiguero, E., Kharraz, Y., Serrano, A. L., & Muñoz-Cánoves, P. (2012) · Cell Cycle · doi:10.4161/cc.11.5.19374 · Cited by 30 · see citing works

The Innate Immune System

Heeg, K. M. (2007) · Neuroimmune biology · doi:10.1016/s1567-7443(07)00205-0

Aspects of the innate and adaptive immune responses to acute infections with BVDV

Brackenbury, L. S., Carr, B. V., & Charleston, B. (2003) · Veterinary Microbiology · doi:10.1016/j.vetmic.2003.09.004 · Cited by 58 · see citing works

Do adaptive immune cells suppress or activate innate immunity?

Zhao, J., Yang, X., Auh, S. L., Kim, K. D., Tang, H., & Fu, Y. (2008) · Trends in Immunology · doi:10.1016/j.it.2008.10.003 · Cited by 40 · see citing works

Earthworm and innate immunity

Liu, Z., & Niu, B. (2008) · Int J Immunol · doi:10.3760/cma.j.issn.1673-4394.2008.04.005

Innate and adaptive immunity

Noakes, P. S., & Michaelis, L. J. (2013) · Elsevier eBooks · doi:10.1533/9780857095749.1.3 · Cited by 12 · see citing works