Infectious immunity in the central nervous system and brain function

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

Kawai, T., & Akira, S. (2010) · Nature Immunology · doi:10.1038/ni.1863 · Cited by 9,304

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

Iliff, J. J., Wang, M., Liao, Y., Plogg, B. A., Peng, W., Gundersen, G. A., Benveniste, H., Vates, G. E., Deane, R., Goldman, S. A., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003748 · Cited by 5,824

Structural and functional features of central nervous system lymphatic vessels

Louveau, A., Smirnov, I., Keyes, T. J., Eccles, J. D., Rouhani, S. J., Peske, J. D., Derecki, N. C., Castle, D., Mandell, J. W., Lee, K. S., et al. (2015) · Nature · doi:10.1038/nature14432 · Cited by 4,413

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

Schafer, D. P., Lehrman, E. K., Kautzman, A. G., Koyama, R., Mardinly, A. R., Yamasaki, R., Ransohoff, R. M., Greenberg, M. E., Barres, B. A., & Stevens, B. (2012) · Neuron · doi:10.1016/j.neuron.2012.03.026 · Cited by 4,089

The blood-brain barrier

Daneman, R., & Prat, A. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020412 · Cited by 3,437

Complement and microglia mediate early synapse loss in Alzheimer mouse models

Hong, S., Beja-Glasser, V. F., Nfonoyim, B. M., Frouin, A., Li, S., Ramakrishnan, S., Merry, K. M., Shi, Q., Rosenthal, A., Barres, B. A., et al. (2016) · Science · doi:10.1126/science.aad8373 · Cited by 3,343

TREM2 Variants in Alzheimer's Disease

Guerreiro, R., Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., Cruchaga, C., Sassi, C., Kauwe, J. S. K., Younkin, S., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1211851 · Cited by 3,020

High-Level Neuronal Expression of Aβ1–42in Wild-Type Human Amyloid Protein Precursor Transgenic Mice: Synaptotoxicity without Plaque Formation

Mucke, L., Masliah, E., Yu, G.-Q., Mallory, M., Rockenstein, E. M., Tatsuno, G., Hu, K., Kholodenko, D., Johnson-Wood, K., & McConlogue, L. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-11-04050.2000 · Cited by 1,856

Synaptic scaling mediated by glial TNF-α

Stellwagen, D., & Malenka, R. C. (2006) · Nature · doi:10.1038/nature04671 · Cited by 1,715

Microglial interactions with synapses are modulated by visual experience

Tremblay, M.-È., Lowery, R. L., & Majewska, A. K. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000527 · Cited by 1,542

Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study

Granerod, J., Ambrose, H. E., Davies, N. W., Clewley, J. P., Walsh, A. L., Morgan, D., Cunningham, R., Zuckerman, M., Mutton, K. J., Solomon, T., et al. (2010) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(10)70222-x · Cited by 1,358

Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis

Hughes, E. G., Peng, X., Gleichman, A. J., Lai, M., Zhou, L., Tsou, R., Parsons, T. D., Lynch, D. R., Dalmau, J., & Balice-Gordon, R. J. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.0167-10.2010 · Cited by 1,143

Myelination and support of axonal integrity by glia

Nave, K.-A. (2010) · Nature · doi:10.1038/nature09614 · Cited by 1,062

Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway

Lehnardt, S., Massillon, L., Follett, P., Jensen, F. E., Ratan, R., Rosenberg, P. A., Volpe, J. J., & Vartanian, T. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1432609100 · Cited by 1,052

IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia

Wang, Y., Szretter, K. J., Vermi, W., Gilfillan, S., Rossini, C., Cella, M., Barrow, A. D., Diamond, M. S., & Colonna, M. (2012) · Nature Immunology · doi:10.1038/ni.2360 · Cited by 1,011

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer’s disease

Kumar, D. K. V., Choi, S. H., Washicosky, K. J., Eimer, W. A., Tucker, S., Ghofrani, J., Lefkowitz, A., McColl, G., Goldstein, L. E., Tanzi, R. E., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aaf1059 · Cited by 971

The movers and shapers in immune privilege of the CNS

Engelhardt, B., Vajkoczy, P., & Weller, R. O. (2017) · Nature Immunology · doi:10.1038/ni.3666 · Cited by 893

Regulation of synaptic connectivity by glia.

Eroglu, C., & Barres, B. A. (2010) · Nature · doi:10.1038/nature09612 · Cited by 813

Regulation of learning and memory by meningeal immunity: a key role for IL-4

Derecki, N. C., Cardani, A. N., Yang, C. H., Quinnies, K. M., Crihfield, A., Lynch, K. R., & Kipnis, J. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20091419 · Cited by 800

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Lui, H., Zhang, J., Makinson, S. R., Cahill, M. K., Kelley, K. W., Huang, H.-Y., Shang, Y., Oldham, M. C., Martens, L. H., Gao, F., et al. (2016) · Cell · doi:10.1016/j.cell.2016.04.001 · Cited by 729

Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour

Filiano, A. J., Xu, Y., Tustison, N. J., Marsh, R. L., Baker, W., Smirnov, I., Overall, C. C., Gadani, S. P., Turner, S. D., Weng, Z., et al. (2016) · Nature · doi:10.1038/nature18626 · Cited by 697

A complement–microglial axis drives synapse loss during virus-induced memory impairment

Vasek, M. J., Garber, C., Dorsey, D., Durrant, D. M., Bollman, B., Soung, A., Yu, J., Perez-Torres, C., Frouin, A., Wilton, D. K., et al. (2016) · Nature · doi:10.1038/nature18283 · Cited by 671

ACYCLOVIR VERSUS VIDARABINE IN HERPES SIMPLEX ENCEPHALITIS

Sköldenberg, B., Alestig, K., Burman, L., Forkman, A., Lövgren, K., Norrby, R., Stiernstedt, G., Forsgren, M., Bergström, T., Dahlqvist, E., et al. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92623-0 · Cited by 610

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer’s disease

Jones, L., Holmans, P. A., Hamshere, M. L., Harold, D., Moskvina, V., Ivanov, D., Pocklington, A., Abraham, R., Hollingworth, P., Sims, R., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013950 · Cited by 606

Resolving postoperative neuroinflammation and cognitive decline

Terrando, N., Eriksson, L. I., Ryu, J. K., Yang, T., Monaco, C. G., Feldmann, M., Fagerlund, M. J., Charo, I. F., Akassoglou, K., & Maze, M. (2011) · Annals of Neurology · doi:10.1002/ana.22664 · Cited by 582

Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors

Vyas, A., Kim, S.-K., Giacomini, N., Boothroyd, J. C., & Sapolsky, R. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0608310104 · Cited by 580

IL-4 in the brain: a cytokine to remember

Gadani, S. P., Cronk, J. C., Norris, G. T., & Kipnis, J. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1202246 · Cited by 549

A Global Perspective on the Epidemiology of West Nile Virus

Kramer, L. D., Styer, L. M., & Ebel, G. D. (2007) · Annual Review of Entomology · doi:10.1146/annurev.ento.53.103106.093258 · Cited by 524

Herpes Simplex Virus-1 Encephalitis in Adults: Pathophysiology, Diagnosis, and Management

Bradshaw, M. J., & Venkatesan, A. (2016) · Neurotherapeutics · doi:10.1007/s13311-016-0433-7 · Cited by 510

Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

Planagumà, J., Leypoldt, F., Mannara, F., Cuesta, J., Martín‐García, E., Aguilar, E., Titulaer, M. J., Petit‐Pedrol, M., Jain, A., Balice‐Gordon, R. J., et al. (2014) · Brain · doi:10.1093/brain/awu310 · Cited by 489

Phagocyte-derived catecholamines enhance acute inflammatory injury

Flierl, M. A., Rittirsch, D., Nadeau, B. A., Chen, A. J., Sarma, J. V., Zetoune, F. S., McGuire, S. R., List, R. P., Day, D. E., Hoesel, L. M., et al. (2007) · Nature · doi:10.1038/nature06185 · Cited by 475

Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory response.

Waage, A., Halstensen, A. I., Shalaby, R., Brandtzaeg, P., Kierulf, P., & Espevik, T. (1989) · The Journal of Experimental Medicine · doi:10.1084/jem.170.6.1859 · Cited by 454

Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation

Bardehle, S., Krüger, M., Buggenthin, F., Schwausch, J., Ninkovic, J., Clevers, H. C., Snippert, H. J. G., Theis, F. J., Meyer‐Luehmann, M., Bechmann, I., et al. (2013) · Nature Neuroscience · doi:10.1038/nn.3371 · Cited by 448

Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [11C]PBR28 PET Brain Imaging Study

Bloomfield, P. S., Selvaraj, S., Veronese, M., Rizzo, G., Bertoldo, A., Owen, D. R., Bloomfield, M., Bonoldi, I., Kalk, N. J., Turkheimer, F., et al. (2015) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2015.14101358 · Cited by 446

Roles of microglia in brain development, tissue maintenance and repair

Michell‐Robinson, M. A., Touil, H., Healy, L. M., Owen, D. R., Durafourt, B. A., Bar‐Or, A., Antel, J. P., & Moore, C. S. (2015) · Brain · doi:10.1093/brain/awv066 · Cited by 435

Autoimmune encephalopathies

Leypoldt, F., Armangué, T., & Dalmau, J. O. (2014) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12553 · Cited by 424

Do glia drive synaptic and cognitive impairment in disease?

Chung, W.-S., Welsh, C. A., Barres, B. A., & Stevens, B. (2015) · Nature Neuroscience · doi:10.1038/nn.4142 · Cited by 385

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid

Schläger, C., Körner, H., Krueger, M., Vidoli, S., Haberl, M., Mielke, D., Brylla, E., Issekutz, T., Cabañas, C., Nelson, P. J., et al. (2016) · Nature · doi:10.1038/nature16939 · Cited by 372

Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling

Habbas, S., Santello, M., Becker, D., Stubbe, H., Zappia, G., Liaudet, N., Klaus, F. R., Kollias, G., Fontana, A., Pryce, C. R., et al. (2015) · Cell · doi:10.1016/j.cell.2015.11.023 · Cited by 347

Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis

Mikasova, L., De Rossi, P., Bouchet, D., Georges, F., Rogemond, V., Didelot, A., Meissirel, C., Honnorat, J., & Groc, L. (2012) · Brain · doi:10.1093/brain/aws092 · Cited by 341

IFN-γ Production by Amyloid β–Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer’s Disease

Browne, T. C., McQuillan, K., McManus, R. M., O’Reilly, J.-A., Mills, K. H. G., & Lynch, M. A. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1200947 · Cited by 330

Pathophysiology of Bacterial Meningitis: Mechanism(s) of Neuronal Injury

Scheld, W. M., Koedel, U., Nathan, B. R., & Pfister, H. (2002) · The Journal of Infectious Diseases · doi:10.1086/344939 · Cited by 325

Epidemiology of cryptococcal meningitis in the US: 1997–2009

Pyrgos, V., Seitz, A. E., Steiner, C. A., Prevots, D. R., & Williamson, P. R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0056269 · Cited by 309

Tuberculosis of the central nervous system

Garg, R. K. (1999) · Postgraduate Medical Journal · doi:10.1136/pgmj.75.881.133 · Cited by 309

Autoimmune post–herpes simplex encephalitis of adults and teenagers

Armangué, T., Morís, G., Extremera, V. C., Conde, C. E., Rostasy, K. M., Erro, M. E., Portilla-Cuenca, J. C., Turón‐Viñas, E., Málaga, I., Cabello, B. M., et al. (2015) · Neurology · doi:10.1212/wnl.0000000000002125 · Cited by 272

Neuroprotection by a caspase inhibitor in acute bacterial meningitis

Braun, J., Novak, R., Herzog, K., Bodner, S. M., Cleveland, J. L., & TUOMANEN, E. I. (1999) · Nature Medicine · doi:10.1038/6514 · Cited by 263

Innate immunity against HIV-1 infection

Altfeld, M. A., & Gale, M. (2015) · Nature Immunology · doi:10.1038/ni.3157 · Cited by 260

Viral Pathogen-Associated Molecular Patterns Regulate Blood-Brain Barrier Integrity via Competing Innate Cytokine Signals

Daniels, B. P., Holman, D. W., Cruz-Orengo, L., Jujjavarapu, H., Durrant, D. M., & Klein, R. S. (2014) · mBio · doi:10.1128/mbio.01476-14 · Cited by 235

Interferon-λ restricts West Nile virus neuroinvasion by tightening the blood-brain barrier

Lazear, H. M., Daniels, B. P., Pinto, A. K., Huang, A. C., Vick, S. C., Doyle, S. E., Gale, M., Klein, R. S., & Diamond, M. S. (2015) · Science Translational Medicine · doi:10.1126/scitranslmed.aaa4304 · Cited by 234

Differential innate immune response programs in neuronal subtypes determine susceptibility to infection in the brain by positive-stranded RNA viruses

Cho, H., Proll, S. C., Szretter, K. J., Katze, M. G., Gale, M., & Diamond, M. S. (2013) · Nature Medicine · doi:10.1038/nm.3108 · Cited by 228

Microglia-Dependent Alteration of Glutamatergic Synaptic Transmission and Plasticity in the Hippocampus during Peripheral Inflammation

Riazi, K., Galic, M. A., Kentner, A. C., Reid, A. Y., Sharkey, K. A., & Pittman, Q. J. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.4485-14.2015 · Cited by 228

Herpes simplex virus encephalitis: Clinical manifestations, diagnosis and outcome in 106 adult patients

Sili, U., Kaya, A., & Mert, A. (2014) · Journal of Clinical Virology · doi:10.1016/j.jcv.2014.03.010 · Cited by 225

Astrocytic dysfunction: Insights on the role in neurodegeneration

Rossi, D., & Volterra, A. (2009) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2009.07.012 · Cited by 225

TLR4-activated microglia require IFN-γ to induce severe neuronal dysfunction and death in situ

Papageorgiou, I. E., Lewen, A., Galow, L. V., Cesetti, T., Scheffel, J., Regen, T., Hanisch, U., & Kann, O. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1513853113 · Cited by 225

Alpha-Synuclein Expression Restricts RNA Viral Infections in the Brain

Beatman, E. L., Massey, A. R., Shives, K. D., Burrack, K. S., Chamanian, M., Morrison, T. E., & Beckham, J. D. (2015) · Journal of Virology · doi:10.1128/jvi.02949-15 · Cited by 219

Lack of Neuronal IFN-β-IFNAR Causes Lewy Body- and Parkinson’s Disease-like Dementia

Ejlerskov, P., Hultberg, J. G., Wang, J., Carlsson, R., Ambjørn, M., Kuss, M., Liu, Y., Porcu, G., Kolkova, K., Friis Rundsten, C., et al. (2015) · Cell · doi:10.1016/j.cell.2015.08.069 · Cited by 211

Neurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondii

Cabral, C. M., Tuladhar, S., Dietrich, H. K., Nguyen, E. T., MacDonald, W. R., Trivedi, T., Devineni, A., & Koshy, A. A. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005447 · Cited by 209

Comparison and Temporal Trends of Three Groups with Cryptococcosis: HIV-Infected, Solid Organ Transplant, and HIV-Negative/Non-Transplant

Bratton, E. W., Husseini, N. E., Chastain, C. A., Lee, M. S., Poole, C., Stürmer‎, T., Juliano, J. J., Weber, D. J., & Perfect, J. R. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043582 · Cited by 203

Enveloped Viruses Disable Innate Immune Responses in Dendritic Cells by Direct Activation of TAM Receptors

Bhattacharyya, S., Zagórska, A., Lew, E. D., Shrestha, B., Rothlin, C. V., Naughton, J., Diamond, M., Lemke, G., & Young, J. A. T. (2013) · Cell Host & Microbe · doi:10.1016/j.chom.2013.07.005 · Cited by 202

Toxoplasma gondii‐induced neuronal alterations

Parlog, A., Schlüter, D., & Dunay, I. R. (2014) · Parasite Immunology · doi:10.1111/pim.12157 · Cited by 199

Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice

Djukic, M. (2006) · Brain · doi:10.1093/brain/awl206 · Cited by 195

A cytokine network involving brain-borne IL-1β, IL-1ra, IL-18, IL-6, and TNFα operates during long-term potentiation and learning

del Rey, A., Balschun, D., Wetzel, W., Randolf, A., & Besedovsky, H. O. (2013) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2013.05.011 · Cited by 190

Herpes simplex virus–1 encephalitis can trigger anti-NMDA receptor encephalitis: Case report

Leypoldt, F., Titulaer, M. J., Aguilar, E., Walther, J., Bönstrup, M., Havemeister, S., Teegen, B., Lütgehetmann, M., Rosenkranz, M., Magnus, T. U., et al. (2013) · Neurology · doi:10.1212/wnl.0b013e3182a9f531 · Cited by 188

Targeted CNS Expression of Interferon-γ in Transgenic Mice Leads to Hypomyelination, Reactive Gliosis, and Abnormal Cerebellar Development

Corbin, J. G., Kelly, D., Rath, E. M., Baerwald, K. D., Suzuki, K., & Popko, B. (1996) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1996.0026 · Cited by 184

Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment

Blank, T., Detje, C. N., Spieß, A., Hagemeyer, N., Brendecke, S. M., Wolfart, J., Staszewski, O., Zöller, T., Papageorgiou, I. E., Schneider, J., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.04.005 · Cited by 182

Meningeal and Perivascular Macrophages of the Central Nervous System Play a Protective Role During Bacterial Meningitis

Polfliet, M. M. J., Zwijnenburg, P. J. G., van Furth, A. M., van der Poll, T., Döpp, E. A., de Lavalette, C. R., van Kesteren-Hendrikx, E. M. L., van Rooijen, N., Dijkstra, C. D., & van den Berg, T. K. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.8.4644 · Cited by 180

West Nile virus infection: MR imaging findings in the nervous system.

Ali, M. W., Safriel, Y. I., Sohi, J., Llave, A., & Weathers, S. (2005) · PubMed Central · Cited by 178

Protective immune responses against West Nile virus are primed by distinct complement activation pathways

Mehlhop, E., & Diamond, M. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20052388 · Cited by 175

TLR3 deficiency renders astrocytes permissive to herpes simplex virus infection and facilitates establishment of CNS infection in mice

Reinert, L. S., Harder, L., Holm, C. K., Iversen, M. B., Horan, K., Dagnæs‐Hansen, F., Ulhøi, B. P., Holm, T. H., Mogensen, T. H., Owens, T., et al. (2012) · Journal of Clinical Investigation · doi:10.1172/jci60893 · Cited by 171

Central nervous system tuberculosis.

Cherian, A., & Thomas, S. (2011) · PubMed Central · Cited by 169

2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo

Szretter, K. J., Daniels, B. P., Cho, H., Gainey, M. D., Yokoyama, W. M., Gale, M., Virgin, H. W., Klein, R. S., Sen, G. C., & Diamond, M. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002698 · Cited by 168

Chemokines in the balance: maintenance of homeostasis and protection at CNS barriers

Williams, J. L., Holman, D. W., & Klein, R. S. (2014) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2014.00154 · Cited by 165

GLT-1-Dependent Disruption of CNS Glutamate Homeostasis and Neuronal Function by the Protozoan Parasite Toxoplasma gondii

David, C. N., Frias, E. S., Szu, J. I., Vieira, P. A., Hubbard, J. A., Lovelace, J. W., Marena, M., Worth, D., McGovern, K. E., Ethell, I. M., et al. (2016) · PLoS Pathogens · doi:10.1371/journal.ppat.1005643 · Cited by 165

The clinical spectrum of sporadic and familial forms of frontotemporal dementia

Woollacott, I., & Rohrer, J. D. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13654 · Cited by 163

Paradoxical Immune Responses in Non-HIV Cryptococcal Meningitis

Panackal, A. A., Wuest, S. C., Lin, Y.-C., Wu, T., Zhang, N., Kosa, P., Komori, M., Blake, A., Browne, S. K., Rosen, L. B., et al. (2015) · PLOS Pathogens · doi:10.1371/journal.ppat.1004884 · Cited by 162

Fever and sickness behavior: Friend or foe?

Harden, L. M., Kent, S., Pittman, Q. J., & Roth, J. (2015) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2015.07.012 · Cited by 161

Glutamate Release from Astrocytes in Physiological Conditions and in Neurodegenerative Disorders Characterized by Neuroinflammation

Vesce, S., Rossi, D., Brambilla, L., & Volterra, A. (2007) · International review of neurobiology · doi:10.1016/s0074-7742(07)82003-4 · Cited by 159

Global research priorities for infections that affect the nervous system

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Long-term Sequelae of Childhood Bacterial Meningitis

Chandran, A., Herbert, H. K., Misurski, D. A., & Santosham, M. (2010) · The Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3181ef25f7 · Cited by 157

Neurological sequelae resulting from encephalitic alphavirus infection

Ronca, S. E., Dineley, K. T., & Paessler, S. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00959 · Cited by 157

The TAM receptor Mertk protects against neuroinvasive viral infection by maintaining blood-brain barrier integrity

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Experimental pneumococcal meningitis: Cerebrovascular alterations, brain edema, and meningeal inflammation are linked to the production of nitric oxide

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Host persistence: exploitation of anti-inflammatory pathways by Toxoplasma GONDII

Aliberti, J. (2005) · Nature reviews. Immunology · doi:10.1038/nri1547 · Cited by 150

Cerebrospinal Fluid Cytokine Profiles Predict Risk of Early Mortality and Immune Reconstitution Inflammatory Syndrome in HIV-Associated Cryptococcal Meningitis

Jarvis, J. N., Meintjes, G., Bicanic, T., Buffa, V., Hogan, L., Mo, S., Tomlinson, G., Kropf, P., Noursadeghi, M., & Harrison, T. S. (2015) · PLOS Pathogens · doi:10.1371/journal.ppat.1004754 · Cited by 150

Mechanisms of injury in bacterial meningitis

Gerber, J., & Nau, R. (2010) · Current Opinion in Neurology · doi:10.1097/wco.0b013e32833950dd · Cited by 149

The choroid plexus—a multi-role player during infectious diseases of the CNS

Schwerk, C., Tenenbaum, T., Kim, K. S., & Schroten, H. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00080 · Cited by 147

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