Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells

Isolation of Putative Progenitor Endothelial Cells for Angiogenesis

Asahara, T., Murohara, T., Sullivan, A., Silver, M., van der Zee, R., Li, T., Witzenbichler, B., Schatteman, G., & Isner, J. M. (1997) · Science · doi:10.1126/science.275.5302.964 · Cited by 8,725

Angiogenesis in cancer, vascular, rheumatoid and other disease

Folkman, J. (1995) · Nature Medicine · doi:10.1038/nm0195-27 · Cited by 7,627

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

Dimmeler, S., Fleming, I., Fisslthaler, B., Hermann, C., Busse, R., & Zeiher, A. M. (1999) · Nature · doi:10.1038/21224 · Cited by 3,591

Circulating endothelial progenitor cells, vascular function, and cardiovascular risk

Hill, J. M., Zalos, G., Halcox, J. P. J., Schenke, W. H., Waclawiw, M. A., Quyyumi, A. A., & Finkel, T. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022287 · Cited by 3,423

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

Lyden, D., Hattori, K., Dias, S., Costa, C., Blaikie, P., Butros, L., Chadburn, A., Heissig, B., Marks, W., Witte, L., et al. (2001) · Nature Medicine · doi:10.1038/nm1101-1194 · Cited by 1,860

S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death

Gu, Z., Kaul, M., Yan, B., Kridel, S. J., Cui, J., Strongin, A., Smith, J. W., Liddington, R. C., & Lipton, S. A. (2002) · Science · doi:10.1126/science.1073634 · Cited by 950

Nitric oxide synthases: regulation and function

Forstermann, U., & Sessa, W. C. (2012) · European Heart Journal · doi:10.1093/eurheartj/ehr304 · Cited by 4,409

Endothelial Function and Dysfunction: Testing and Clinical Relevance

Deanfield, J. E., Halcox, J. P., & Rabelink, T. J. (2007) · Circulation · doi:10.1161/circulationaha.106.652859 · Cited by 2,710

Endothelial Progenitor Cells: Characterization and Role in Vascular Biology

Urbich, C., & Dimmeler, S. (2004) · Circulation Research · doi:10.1161/01.res.0000137877.89448.78 · Cited by 2,369

PLEIOTROPIC EFFECTS OF STATINS

Liao, J. K., & Laufs, U. (2005) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.45.120403.095748 · Cited by 1,994

Endothelial Function: Cardiac Events

Lerman, A., & Zeiher, A. M. (2005) · Circulation · doi:10.1161/01.cir.0000153339.27064.14 · Cited by 1,096

Role of microRNAs in vascular diseases, inflammation, and angiogenesis

Urbich, C., Kuehbacher, A., & Dimmeler, S. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn156 · Cited by 880

Synergistic Neovascularization by Mixed Transplantation of Early Endothelial Progenitor Cells and Late Outgrowth Endothelial Cells: The Role of Angiogenic Cytokines and Matrix Metalloproteinases

Yoon, C.-H., Hur, J., Park, K.-W., Kim, J.-H., Lee, C.-S., Oh, I.-Y., Kim, T.-Y., Cho, H.-J., Kang, H.-J., Chae, I.-H., et al. (2005) · Circulation · doi:10.1161/circulationaha.104.503433 · Cited by 601

Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors

Butler, J. M., Kobayashi, H., & Rafii, S. (2010) · Nature Reviews Cancer · doi:10.1038/nrc2791 · Cited by 578

Molecular Basis for the Regulation of Angiogenesis by Thrombospondin-1 and -2

Lawler, P. R., & Lawler, J. (2012) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a006627 · Cited by 532

MicroRNA 217 Modulates Endothelial Cell Senescence via Silent Information Regulator 1

Menghini, R., Casagrande, V., Cardellini, M., Martelli, E., Terrinoni, A., Amati, F., Vasa-Nicotera, M., Ippoliti, A., Novelli, G., Melino, G., et al. (2009) · Circulation · doi:10.1161/circulationaha.109.864629 · Cited by 482

eNOS activation by physical forces: from short-term regulation of contraction to chronic remodeling of cardiovascular tissues

Balligand, J.-L., Feron, O., & Dessy, C. (2009) · Physiological Reviews · doi:10.1152/physrev.00042.2007 · Cited by 477

Molecular mechanisms underlying the activation of eNOS

Fleming, I. (2010) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-009-0767-7 · Cited by 437

Nitrite as Regulator of Hypoxic Signaling in Mammalian Physiology

van Faassen, E. E., Bahrami, S., Feelisch, M., Hogg, N., Kelm, M., Kim‐Shapiro, D. B., Kozlov, A. V., Li, H., Lundberg, J. O., Mason, R., et al. (2009) · Medicinal Research Reviews · doi:10.1002/med.20151 · Cited by 435

Statin-Induced Improvement of Endothelial Progenitor Cell Mobilization, Myocardial Neovascularization, Left Ventricular Function, and Survival After Experimental Myocardial Infarction Requires Endothelial Nitric Oxide Synthase

Landmesser, U., Engberding, N., Bahlmann, F. H., Schaefer, A., Wiencke, A., Heineke, A., Spiekermann, S., Hilfiker-Kleiner, D., Templin, C., Kotlarz, D., et al. (2004) · Circulation · doi:10.1161/01.cir.0000143232.67642.7a · Cited by 423

Endothelial progenitor cells in cardiovascular disorders

Shantsila, E., Watson, T., & Lip, G. Y. H. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.09.050 · Cited by 413

Aging and disease as modifiers of efficacy of cell therapy

Dimmeler, S., & Leri, A. (2008) · Circulation Research · doi:10.1161/circresaha.108.175943 · Cited by 379

Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities

Thomas, S. R., Witting, P. K., & Drummond, G. R. (2008) · Antioxidants & Redox Signaling · doi:10.1089/ars.2008.2027 · Cited by 383

Role of β2-integrins for homing and neovascularization capacity of endothelial progenitor cells

Chavakis, E., Aicher, A., Heeschen, C., Sasaki, K.-I., Kaiser, R., El Makhfi, N., Urbich, C., Peters, T., Scharffetter-Kochanek, K., Zeiher, A. M., et al. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20041402 · Cited by 304

Effects of Statins on 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibition Beyond Low-Density Lipoprotein Cholesterol

Liao, J. K. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.06.009 · Cited by 304

Vascular repair by circulating endothelial progenitor cells: the missing link in atherosclerosis?

Dimmeler, S., & Zeiher, A. M. (2004) · Journal of Molecular Medicine · doi:10.1007/s00109-004-0580-x · Cited by 294

A protocol for phenotypic detection and enumeration of circulating endothelial cells and circulating progenitor cells in human blood

Duda, D. G., Cohen, K. S., Scadden, D. T., & Jain, R. K. (2007) · Nature Protocols · doi:10.1038/nprot.2007.111 · Cited by 275

Is exercise training an effective therapy targeting endothelial dysfunction and vascular wall inflammation?

Ribeiro, F., Alves, A. J., Duarte, J. A., & Oliveira, J. (2010) · International Journal of Cardiology · doi:10.1016/j.ijcard.2009.09.548 · Cited by 169

The clinical significance of endothelial dysfunction

Landmesser, U., & Drexler, H. (2005) · Current Opinion in Cardiology · doi:10.1097/01.hco.0000179821.11071.79 · Cited by 142

Dietary nitrate supplementation improves revascularization in chronic ischemia

Hendgen-Cotta, U. B., Luedike, P., Totzeck, M., Kropp, M., Schicho, A., Stock, P., Rammos, C., Niessen, M., Heiss, C., Lundberg, J. O., et al. (2012) · Circulation · doi:10.1161/circulationaha.112.112912 · Cited by 110

Chronic administration of the probiotic kefir improves the endothelial function in spontaneously hypertensive rats

Friques, A. G. F., Arpini, C. M., Kalil, I. C., Gava, A. L., Leal, M. A., Porto, M. L., Nogueira, B. V., Dias, A. T., Andrade, T. U., Pereira, T. M. C., et al. (2015) · Journal of Translational Medicine · doi:10.1186/s12967-015-0759-7 · Cited by 108

Repair Mechanisms of the Neurovascular Unit after Ischemic Stroke with a Focus on VEGF

Moon, S., Chang, M.-S., Koh, S.-H., & Choi, Y. K. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22168543 · Cited by 104

Endothelial nitric oxide synthase: A potential therapeutic target for cerebrovascular diseases

Zhu, J., Song, W., Li, L., & Fan, X. (2016) · Molecular Brain · doi:10.1186/s13041-016-0211-9 · Cited by 96

Exercise Interventions and Peripheral Arterial Function: Implications for Cardio-Metabolic Disease

Phillips, S. A., Mahmoud, A. M., Brown, M. D., & Haus, J. M. (2015) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2014.12.005 · Cited by 78

Decreased Endothelial Progenitor Cells (EPCs) and increased Natural Killer (NK) cells in peripheral blood as possible early markers of preeclampsia: a case-control analysis

Laganà, A. S., Giordano, D., Loddo, S., Zoccali, G., Vitale, S. G., Santamaria, A., Buemi, M., & D’Anna, R. (2017) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-017-4296-x · Cited by 71

Central Role of Calcium-Dependent Tyrosine Kinase PYK2 in Endothelial Nitric Oxide Synthase–Mediated Angiogenic Response and Vascular Function

Matsui, A., Okigaki, M., Amano, K., Adachi, Y., Jin, D., Takai, S., Yamashita, T., Kawashima, S., Kurihara, T., Miyazaki, M., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.645416 · Cited by 47

Mechanisms Underlying Cell Therapy in Liver Fibrosis: An Overview

Pinheiro, D., Dias, I., Ribeiro Silva, K., Stumbo, A. C., Thole, A., Cortez, E., de Carvalho, L., Weiskirchen, R., & Carvalho, S. (2019) · Cells · doi:10.3390/cells8111339 · Cited by 46

Mediterranean nutraceutical foods: Strategy to improve vascular ageing

Accardi, G., Aiello, A., Gambino, C. M., Virruso, C., Caruso, C., & Candore, G. (2016) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2016.02.007 · Cited by 32

Accelerated cellular senescence as underlying mechanism for functionally impaired bone marrow-derived progenitor cells in ischemic heart disease

Nollet, E., Hoymans, V. Y., Rodrigus, I. R., De Bock, D., Dom, M., Van Hoof, V. O. M., Vrints, C. J., & Van Craenenbroeck, E. M. (2017) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2017.03.023 · Cited by 17

Chronic Hyperuricemia Impairs Blood Flow Recovery in the Ischemic Hindlimb through Suppression of Endothelial Progenitor Cells

Chen, I.-C., Kuo, C.-S., Wu, C.-C., Tsai, H.-Y., Lin, C.-P., Li, S.-Y., Chou, R.-H., Huang, P.-H., Chen, J.-W., & Lin, S.-J. (2018) · Oncotarget · doi:10.18632/oncotarget.24290 · Cited by 11