The DOI matches its Crossref record; 77 of the 77 references it cites were found in a registry or an index.
The neurobiology of pair bonding.
Abstract
A neurobiological model for pair-bond formation has emerged from studies in monogamous rodents. The neuropeptides oxytocin and vasopressin contribute to the processing of social cues necessary for individual recognition. Mesolimbic dopamine is involved in reinforcement and reward learning. Concurrent activation of neuropeptide and dopamine receptors in the reward centers of the brain during mating results in a conditioned partner preference, observed as a pair bond. Differential regulation of neuropeptide receptor expression may explain species differences in the ability to form pair bonds. These and other studies discussed here have intriguing implications for the neurobiology of social attachment in our own species.
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In the citing paper
“Meta-analyses and systematic reviews indicate that a range of common therapies can indeed be effective in relieving couple distress in many situations [26, 27].”
From Could intranasal oxytocin be used to enhance relationships? Research imperatives, clinical policy, and ethical considerations (2013) · cites this paper as [26]
In the citing paper
“The hypothalamic peptide oxytocin (OXT) has been identified as a key modulator of pair-bonding in men, but its effects in women are still elusive.”
From Hormonal contraceptives suppress oxytocin-induced brain reward responses to the partner’s face (2016) · cites this paper as Young and Wang, 2004
In the citing paper
“A study injecting 3H-leucine into the SON found multiple extrahypothalamic projections, including olfactory bulb, amygdala, cingulum, and locus coeruleus [140].”
From Oxytocin and the Neural Mechanisms Regulating Social Cognition and Affiliative Behavior (2009) · cites this paper as [140]
In the citing paper
“which suggests that species-specific differences in neural distributions of OXTR can reflect the social organisation of the species (20,21).”
From Comparative Perspectives on Oxytocin and Vasopressin Receptor Research in Rodents and Primates: Translational Implications (2016) · cites this paper as [20]
In the citing paper
“OXTR signaling in the NAcc is required for mating-induced partner preference formation, a laboratory proxy of pair bonding (6).”
From Variation in the Oxytocin Receptor Gene Predicts Brain Region–Specific Expression and Social Attachment (2016) · cites this paper as [6]
In the citing paper
“OXTR affects a range of social behaviors in animals including maternal nurturing and bonding (1, 2), social reward and gregariousness (3, 4), social recognition (5), and pair bonding in monogamous species (6–8).”
From Variation in the Oxytocin Receptor Gene Predicts Brain Region–Specific Expression and Social Attachment (2016) · cites this paper as [6]
In the citing paper
“In a socially monogamous rodent, the prairie vole (Microtus ochrogaster), OXTR is enriched in important MLR regions such as the nucleus accumbens (NAcc) and prefrontal cortex (PFC) that constitute part of a neural network for pair bonding (6, 8, 34).”
From Variation in the Oxytocin Receptor Gene Predicts Brain Region–Specific Expression and Social Attachment (2016) · cites this paper as [6]
In the citing paper
“OXTR density is much higher in the NAcc of prairie voles than promiscuous vole species”
From Variation in the Oxytocin Receptor Gene Predicts Brain Region–Specific Expression and Social Attachment (2016) · cites this paper as [6]
In the citing paper
“It is thought that the interface between oxytocin and the dopaminergic reward system may contribute to the success of mother-infant and pair-bonding processes [18,[75][76][77].”
From Food sharing is linked to urinary oxytocin levels and bonding in related and unrelated wild chimpanzees (2014) · cites this paper as [76]
In the citing paper
“Our first studies of the role of the AVPR1a gene in social cognition exemplified by a simple laboratory paradigm converges with a wide range of both animal and human experimentation showing that arginine vasopressin (AVP) and the closely related oxytocin (OT) are key neuropeptides that facilitate social communication, affiliative behaviors and social cognition across mammals [6], [7] .”
From The oxytocin receptor (OXTR) contributes to prosocial fund allocations in the dictator game and the social value orientations task (2009) · cites this paper as [7]
In the citing paper
“By contrast, other related vole species such as the meadow vole (M. pennsylvanicus) and the montane vole (M. montanus) are relatively asocial and do not readily form social bonds, providing a useful point of comparison for identifying neurobiological and genetic systems leading to diversity in social behaviors [2].”
From The prairie vole: An emerging model organism for understanding the social brain (2010) · cites this paper as [2]
In the citing paper
“By contrast, other related vole species such as the meadow vole (M. pennsylvanicus) and the montane vole (M. montanus) are relatively asocial and do not readily form social bonds, providing a useful point of comparison for identifying neurobiological and genetic systems leading to diversity in social behaviors [2].”
From The prairie vole: An emerging model organism for understanding the social brain (2010) · cites this paper as [2]
In the citing paper
“For example, socially monogamous male prairie voles have high densities of AVPR1A binding in the ventral pallidum, a major output of the NAcc, while non-mongamous vole species do not [2].”
From The prairie vole: An emerging model organism for understanding the social brain (2010) · cites this paper as [2]
In the citing paper
“One of these socially monogamous mammals that has provided remarkable insights into the neural and neurogenetic mechanisms of social attachments is the prairie vole (Microtus ochrogaster)”
From Oxytocin and Social Relationships: From Attachment to Bond Disruption (2017) · cites this paper as Young and Wang 2004
In the citing paper
“V1aR signaling in the ventral pallidum and LS promote partner preferences (149), while pair bond-induced aggression is mediated by V1aR in the lateral hypothalamus (43,150).”
From Oxytocin, Vasopressin, and Social Behavior: From Neural Circuits to Clinical Opportunities (2022) · cites this paper as [149]
In the citing paper
“Because animal research has documented that OT is primarily a social bonding hormone that activates socio-emotional neural pathways in the brain 22,23 , we would also expect the effect of OT in humans to be limited to social situations where initiating or establishing partnership is important to realize synergy.”
From A registered replication study on oxytocin and trust (2020) · cites this paper as [23]
In the citing paper
“this finding fits with the crucial function of OT as a female hormone in labor, bonding and parenting both in human- [54], [4] and non-human mammals [55]”
From A direct examination of the effect of intranasal administration of oxytocin on approach-avoidance motor responses to emotional stimuli (2013) · cites this paper as [55]
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“Additionally, OT release in the NAc promotes affiliative social behavior, such as social reward in C57 mice (Dölen et al., 2013; Nardou et al., 2019), pair bonding in prairie voles (Young and Wang, 2004) and maternal behavior in Long–Evans rats (Shahrokh et al., 2010).”
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“, 2010) and are likely involved in affiliative behavior (Young and Wang, 2004).”
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“Such a relationship is expected given that sex is itself a mechanism of social bonding in mammals (Young and Wang, 2004; Young et al., 2005).”
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“…2007), it modulates pair bonding between opposite-sex partners (Cavanaugh, Mustoe, Taylor, & French, 2014; Smith, Agmo, Birnie, & French, 2010; Young & Wang, 2004) and influences prosocial decision making in primates (Brosnan, Talbot, et al., 2015; Chang, Barter, Ebitz, Watson, & Platt, 2012;…”
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“VP innervation in this area has been associated with partner preference in prairie voles (Lim et al., 2004), and density of binding sites for VP is greater in the ventral pallidum of monogamous than polygynous species of rodents and primates (Insel et al., 1994; Young and Wang, 2004).”
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“…a neuromodulator that plays an important role in regulating many social behaviors frommaternal nurturing and bonding (Rilling and Young, 2014) to social recognition (Ferguson et al., 2001; Skuse et al., 2014) and pair bonding (Johnson and Young, 2015; Young and Wang, 2004; Numan and Young., 2016).”
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“…include involvement in memory processes (Dantzer et al., 1987), anxiety (McCarthy et al., 1996; Bale et al., 2001; Ring et al., 2006), and regulation of emotional and social behavior in males and females (Young and Wang, 2004; Heinrichs and Domes, 2008; Neumann, 2008; Skuse and Gallagher, 2009).”
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“…social recognition (Engelmann et al., 1998; Ferguson et al., 2001; Ferguson et al., 2000; Popik and van Ree, 1998), pair bonding (Carter, 1998; Young and Wang, 2004), and maternal behavior (Fahrbach et al., 1984; Keverne and Kendrick, 1992; Pedersen, 1997; Pedersen and Boccia, 2003) in…”
BackgroundBorroto-Escuela, D. O., Cuesta-Marti, C., Lopez-Salas, A., Chruścicka-Smaga, B., Crespo-Ramírez, M., Tesoro-Cruz, E., Palacios-Lagunas, D. A., Perez de la Mora, M., Schellekens, H., & Fuxe, K. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.1055344 · Cited by 38
“Based on the outstanding work of Young and colleagues on the interactions between DA and OXT systems (Young and Wang, 2004) and in line with the results of Romero-Fernandez (Romero-Fernandez et al.”
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BackgroundMiczek, K. A., Nikulina, E. M., Takahashi, A., Covington, H. E., Yap, J. J., Boyson, C. O., Shimamoto, A., & de Almeida, R. M. M. (2011) · Behavior Genetics · doi:10.1007/s10519-011-9462-5 · Cited by 40
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Wei, X., Jiao, Z., Senol, E., Yao, J., Zhao, M., Zhao, Z., Chen, X., Cao, P., Fu, Y., Gao, Z., et al. (2021) · Science China Life Sciences · doi:10.1007/s11427-021-2043-2 · Cited by 40
“Oxytocin also positively modulates pair bonding, motherinfant affiliation, and inter-male social interactions by enhancing social reward to reinforce social interactions (Dölen et al., 2013; Hu et al., 2021; Hung et al., 2017; Young and Wang, 2004).”
BackgroundLudwig, M., Tobin, V. A., Callahan, M. F., Papadaki, E., Becker, A., Engelmann, M., & Leng, G. (2013) · Journal of Neuroendocrinology · doi:10.1111/jne.12046 · Cited by 37
“Finally, central administration of oxytocin or vasopressin modulates several social behaviors including social recognition, memory for peers, development of partner preference and bonding (14, 25-27).”
BackgroundO’Connor, C. M., Marsh‐Rollo, S. E., Aubin‐Horth, N., & Balshine, S. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.10.015 · Cited by 39
The neuroendocrinology of love
Seshadri, K. (2016) · Indian Journal of Endocrinology and Metabolism · doi:10.4103/2230-8210.183479 · Cited by 40
“Breast and nipple stimulation are integral to human sexual activity.[33] Nipple stimulation during lactation is one of the most potent stimulus for OT release.”
BackgroundTully, J., Gabay, A. S., Brown, D., Murphy, D., & Blackwood, N. (2017) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2017.11.017 · Cited by 39
“For example, in prairie voles, oxytocin plays a key role in pair bond formation (Young and Wang, 2004) and reducing fear in social interactions (Carter et al., 2008).”
BackgroundOxytocin and Sensory Network Plasticity
Pekarek, B. T., Hunt, P. J., & Arenkiel, B. R. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.00030 · Cited by 40
“One notable illustration of this is the monogamous prairie vole, in which well-defined expression of Oxtr in only a few distinct brain regions drives the development of monogamous behavior in prairie voles; however, lack of Oxtr expression in meadow voles yields a more solitary animal (Young and Wang, 2004).”
BackgroundSpecification of oxytocinergic and vasopressinergic circuits in the developing mouse brain
Madrigal, M. P., & Jurado, S. (2021) · Communications Biology · doi:10.1038/s42003-021-02110-4 · Cited by 41
Attachment representation modulates oxytocin effects on the processing of own-child faces in fathers
Waller, C., Wittfoth, M., Fritzsche, K., Timm, L., Wittfoth, D., Rottler, E., Heinrichs, M., Buchheim, A., Kiefer, M., & Gündel, H. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.07.003 · Cited by 38
“A p C D M a b c d e f g a A R R A K O F A E 1 s D g M F h 0 Psychoneuroendocrinology 62 (2015) 27–35 Contents lists available at ScienceDirect Psychoneuroendocrinology journa l homepage: www.e lsev ier .com/ locate /psyneuen ttachment representation modulates oxytocin effects on the rocessing of own-child faces in fat…”
Pultorak, J. D., Kelm‐Nelson, C. A., Holt, L. R., Blue, K. V., Ciucci, M. R., & Johnson, A. M. (2015) · Social Neuroscience · doi:10.1080/17470919.2015.1086434 · Cited by 36
“…is similarly implicated in female rodent social attachment and pair bonding (Aragona et al., 2006; Gingrich, Liu, Cascio, Wang, & Insel, 2000; Young & Wang, 2004) as it has direct connections to brain circuitry implicated in reward and multiple neuropeptides associated with affiliation and…”
BackgroundHews, D. K., Hara, E., & Anderson, M. C. (2012) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2011.12.028 · Cited by 36
“Lizard steroid hormone receptors, including the AR, show high sequence homology to mammalian AR [56, 79].”
BackgroundBrain functional networks associated with social bonding in monogamous voles
López-Gutiérrez, M. F., Gracia-Tabuenca, Z., Ortiz, J. J., Camacho, F., Young, L. J., Paredes, R. G., Díaz, N. F., Portillo, W., & Alcauter, S. (2021) · eLife · doi:10.7554/elife.55081 · Cited by 42
Autism - A Neurodevelopmental Journey from Genes to Behaviour
Eapen, V. (2011) · InTech eBooks · doi:10.5772/974 · Cited by 36
New Topics in Vasopressin Receptors and Approach to Novel Drugs: Vasopressin and Pain Perception
Koshimizu, T., & Tsujimoto, G. (2009) · Journal of Pharmacological Sciences · doi:10.1254/jphs.08r18fm · Cited by 36
Fox, A. S., Oakes, T. R., Shelton, S. E., Converse, A. K., Davidson, R. J., & Kalin, N. H. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0409470102 · Cited by 36
Pair bonds and parental behaviour
McGraw, L. A., Székely, T., & Young, L. J. (2010) · Cambridge University Press eBooks · doi:10.1017/cbo9780511781360.023 · Cited by 37
Vicario, A., Mendoza, E., Abellán, A., Scharff, C., & Medina, L. M. (2016) · Brain Structure and Function · doi:10.1007/s00429-016-1229-6 · Cited by 36
“The role of oxytocin and vasopressin is evolutionarily highly conserved, and these peptides act in a sex and species-specific manner (Young and Wang 2004; Carter et al. 2008; Donaldson and Young 2008).”
BackgroundNair, H. P., Gutman, A. R., Davis, M., & Young, L. J. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2524-05.2005 · Cited by 36
“We chose these receptors because species differences in complex social behavior have been linked to vasopressin (AVP) and oxytocin (OXT) (Young et al., 1998a; Goodson and Bass, 2001; Young and Wang, 2004), and stress, anxiety, and regulation of the hypothalamic-pituitary axis are linked to the CRF system and its recep…”
BackgroundMethodInfluentialOlazábal, D. E. (2014) · Journal of Physiology-Paris · doi:10.1016/j.jphysparis.2014.10.002 · Cited by 35
“Briefly, OXT and AVP have been proposed to facilitate parental behavior and pair bonding in females and males respectively (Carter et al., 1995; Wang et al., 2000; Young and Wang, 2004; see Ophir et al., 2012 for an excellent discussion on this topic).”
BackgroundPresynaptic actions of endocannabinoids mediate α-MSH-induced inhibition of oxytocin cells
Sabatier, N., & Leng, G. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00667.2005 · Cited by 52
“Vasopressin and oxytocin are also released centrally, and are involved in several behaviours (47); central release originates in part from parvocellular neurons of the paraventricular nucleus (PVN), but both peptides are also released from the dendrites of magnocellular neurons of the PVN and SON (20).”
Oxytocin And Individual Variation in Parental Care in Prairie Voles
Olazábal, D. E., & Young, L. J. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-374285-8.00021-4 · Cited by 35
Latzman, R. D., Hopkins, W. D., Keebaugh, A. C., & Young, L. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0095741 · Cited by 35
“Across numerous species, AVPR1A has been found to be expressed in the brain and associated with several social behaviors including aggression, territoriality, and pair bonding behaviors among voles, particularly among males (e.g., [26,27]).”
Stimulation of dopamine D 1 receptor improves learning capacity in cooperating cleaner fish
Messias, J. P. M., Santos, T. P., Pinto, M., & Soares, M. C. (2016) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2015.2272 · Cited by 40
Hopf, D., Eckstein, M., Aguilar‐Raab, C., Warth, M., & Ditzen, B. (2020) · Journal of Neuroendocrinology · doi:10.1111/jne.12887 · Cited by 44
The neurochemistry of social reward during development: What have we learned from rodent models?
Manduca, A., Carbone, E., Schiavi, S., Cacchione, C., Buzzelli, V., Campolongo, P., & Trezza, V. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15321 · Cited by 34
“It has been well established that oxytocin modulates social interaction and pair bonding, addiction, as well as social memory (Carter et al. 1992; Ferguson et al. 2000; Leong et al. 2018; Young & Wang, 2004).”
BackgroundFetter-Pruneda, I., Hart, T., Ulrich, Y., Gal, A., Oxley, P. R., Olivos-Cisneros, L., Ebert, M. S., Kazmi, M. A., Garrison, J. L., Bargmann, C. I., et al. (2021) · PLoS Biology · doi:10.1371/journal.pbio.3001305 · Cited by 36
Social Evolution in African Mole-Rats – A Comparative Overview
Faulkes, C. G., & Bennett, N. C. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-65943-1_1 · Cited by 39
Sasaki, K., Ferdousi, F., Fukumitsu, S., Kuwata, H., & Isoda, H. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.112291 · Cited by 37
Current Perspectives on Kisspeptins Role in Behaviour
Mills, E. G., Yang, L., Abbara, A., Dhillo, W. S., & Comninos, A. N. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.928143 · Cited by 34
“Specifically, this was observed to occur in the thalamus and globus pallidus, which are brain regions implicated in romantic love (86, 87), as well as the amygdala, also implicated in bonding (87).”
BackgroundBarrett, C. E., Modi, M. E., Zhang, B. C., Walum, H., Inoue, K., & Young, L. J. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2014.05.041 · Cited by 34
“As pair bond formation requires social learning, attention to relevant social cues, and the drive to preferentially associate with a partner (Young and Wang, 2004), these changes in adult behavior would serve to promote social attachment.”
Self-citationInteractions of Oxytocin and Dopamine—Effects on Behavior in Health and Disease
Petersson, M., & Uvnäs‐Moberg, K. (2024) · Biomedicines · doi:10.3390/biomedicines12112440 · Cited by 44
“Indeed, oxytocin has been demonstrated to be released in the amygdala and the nucleus accumbens in response to sexual behavior [81].”
Considering the Role of Conditioning in Sexual Orientation
Hoffmann, H. (2012) · Archives of Sexual Behavior · doi:10.1007/s10508-012-9915-9 · Cited by 33
Smale, L., Heideman, P. D., & French, J. A. (2005) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.05.002 · Cited by 34
“Recent data suggest that an evolutionary transition between the polygynous pattern of a meadow vole and the monogamous one of a prairie vole may have involved selection favoring individuals with genes that regulate the expression of the V1a vasopressin receptor in a variety of neuronal populations (Young and Wang, 200…”
Neural mechanisms of social learning in the female mouse
Gao, Y., Budlong, C. H., Durlacher, E., & Davison, I. G. (2017) · eLife · doi:10.7554/elife.25421 · Cited by 34
“…convey vital social information, influencing diverse behaviors such as reproduction (Bruce and Parrott, 1960; Kimchi et al., 2007), pair bonding (Young and Wang, 2004), parental care (Dulac et al., 2014; Kendrick et al., 1992; Lévy et al., 2004), individual recognition (Hurst, 2009), and…”
BackgroundCsoltova, E., & Mehinagic, E. (2020) · Frontiers in Psychology · doi:10.3389/fpsyg.2020.02131 · Cited by 41
Althammer, F., Muscatelli, F., Grinevich, V., & Schaaf, C. P. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02054-1 · Cited by 35
Disease-Specific Heteromerization of G-Protein-Coupled Receptors That Target Drugs of Abuse
Gomes, I., Fujita, W., Chandrakala, M. V., & Devi, L. A. (2013) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-386931-9.00009-x · Cited by 35
The neuroevolutionary and neuroaffective psychobiology of the prosocial brain
Panksepp, J. (2012) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780198568308.013.0012 · Cited by 34
Effects of population density on corticosterone levels of prairie voles in the field
Blondel, D. V., Wallace, G., Calderone, S., Gorinshteyn, M., Mary, C. M. S., & Phelps, S. M. (2015) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2015.09.002 · Cited by 35
Meat sharing between male and female Guinea baboons ( Papio papio )
Goffe, A. S., & Fischer, J. (2016) · Primate Biology · doi:10.5194/pb-3-1-2016 · Cited by 33
“Neuro-endocrinological mechanisms play a role in bond formation and maintenance in a variety of species (Young and Wang, 2004) and may also facilitate cooperative activities and food sharing (Wittig et al.”
BackgroundInfluentialCommon Marmosets: A Potential Translational Animal Model of Juvenile Depression
Coelho, N. L. G., Galvão, A. C. D. M., da Silva, F. S., & de Sousa, M. B. C. (2017) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2017.00175 · Cited by 33
Regulating the Social Brain: A New Role for CD38
Young, L. J. (2007) · Neuron · doi:10.1016/j.neuron.2007.04.011 · Cited by 33
“This form of attachment is mediated by an interaction of the OT and dopamine receptor systems in the nucleus accumbens, part of the brain’s reward circuitry (Young and Wang, 2004).”
Backgroundde Vries, G. J., Jardon, M., Reza, M., Rosen, G. J., Immerman, E., & Forger, N. G. (2008) · Endocrinology · doi:10.1210/en.2008-0448 · Cited by 36
Beyond romance: Neural and genetic correlates of altruism in pair-bonds.
Acevedo, B. P., Poulin, M. J., & Brown, L. L. (2019) · Behavioral Neuroscience · doi:10.1037/bne0000293 · Cited by 35
“These findings lend support to research implicating the VP in pair bonding in rodents (Wang, Young, De Vries, & Insel, 1999; Young & Wang, 2004) and primates (Bales et al., 2007; Hinde et al., 2016), but also show that this system is used for empathic and altruistic feelings for strangers.”
Lucht, M. J., Barnow, S., Schroeder, W., Grabe, H. J., Finckh, U., John, U., Freyberger, H. J., & Herrmann, F. H. (2006) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30255 · Cited by 32
“According to several animal studies, the ability to form intense social attachments or pair bonds has a strong biological basis that may be present in humans as well [Young and Wang, 2004].”
BackgroundResultIs Oxytocin Application for Autism Spectrum Disorder Evidence-Based?
Lee, S. Y., Lee, A. R., Hwangbo, R., Han, J., Hong, M., & Bahn, G. H. (2015) · Experimental Neurobiology · doi:10.5607/en.2015.24.4.312 · Cited by 33
“If oxytocin induces social attachment, sexual activity may reinforce sexual bonding [35].”
BackgroundMahovetz, L. M., Young, L. J., & Hopkins, W. D. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12291 · Cited by 33
“…AVPR1A expression, including in relation to a repetitive polymorphism referred to as a microsatellite in the 5′ flanking region of the arginine vasopressin receptor 1A gene (AVPR1A) (Barrett et al. 2013; Donaldson & Young 2013; Hammock & Young 2005, 2006; Hammock et al. 2005; Young & Wang 2004).”
BackgroundHow prior pair-bonding experience affects future bonding behavior in monogamous prairie voles
Harbert, K. J., Pellegrini, M., Gordon, K. M., & Donaldson, Z. R. (2020) · Hormones and Behavior · doi:10.1016/j.yhbeh.2020.104847 · Cited by 32
Wirobski, G., Range, F., Schaebs, F. S., Palme, R., Deschner, T., & Marshall‐Pescini, S. (2020) · Hormones and Behavior · doi:10.1016/j.yhbeh.2020.104901 · Cited by 34
“Oxytocin (OT) is a neuropeptide hormone that facilitates social approach and bonding (Young and Wang, 2004), and enhances the salience of social cues to promote context-appropriate behavioral responses (Oliva et al.”
Background
Metadata
- Authors
- Young, L. J., & Wang, Z.
- Affiliations
- Emory University (US)
- Florida State University (US)
- Corresponding author
- Young, Larry J
- Venue
- Nature Neuroscience
- Published
- 2004-09-26
- Volume
- 7
- Issue
- 10
- Pages
- 1048-1054
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W2055445652
- Cited by
- 1,523
- References
- 76
- Citations by year
- 2026: 42 · 2025: 63 · 2024: 54 · 2023: 64 · 2022: 62 · 2021: 65 · 2020: 73 · 2019: 60 · 2018: 83 · 2017: 85 · 2016: 99 · 2015: 96 · 2014: 86 · 2013: 106 · 2012: 85
- FWCI
- 6.10
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Keywords
- pair bonding, monogamy, oxytocin, vasopressin, mesolimbic dopamine system, reward learning, social attachment, individual recognition, social behavior
- MeSH terms
- Animals, Brain, Dopamine, Humans, Neural Pathways, Neuropeptides, Pair Bond, Reward, Receptors, Neuropeptide, Models, Animal
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