Comparative analysis of oxytocin receptor density in the nucleus accumbens: an adaptation for female and male alloparental care?

Olazábal, Daniel E.

doi:10.1016/j.jphysparis.2014.10.002

Cited by 35Neuroendocrine regulation and behaviorPrimate Behavior and EcologyAnimal Behavior and Reproduction

Comparative analysis of oxytocin receptor density in the nucleus accumbens: an adaptation for female and male alloparental care?

Olazábal, Daniel E.·2014·Journal of Physiology-Paris

DOI 10.1016/j.jphysparis.2014.10.002

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Abstract

Parental behavior is commonly displayed by progenitors. However, other individuals, genetically related (e.g. siblings, aunts, uncles) or not with the newborns, also display parental behavior (commonly called alloparental, or adoptive behavior). I hypothesize that species that live in family or social groups where other non-reproductive members (males and females) take care of infants, have brain adaptations to promote or facilitate that behavioral response. The present work revises the evidence supporting the hypothesis that high density of oxytocin receptors (OXTR) in the nucleus accumbens (NA) is one of those adaptations. All species known to have high NA OXTR show not only female, but also male alloparental care. Therefore, I predict that high NA OXTR could be present in all species in which juvenile and adult male alloparental behavior have been observed. Strategies to test this and other alternative working hypothesis and its predictions are presented.

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OTR densities in the NAc correlate with socially monogamous mating strategies and other forms of social behavioral variation in prairie voles and other mammals.
“OTR densities in the NAc correlate with socially monogamous mating strategies and other forms of social behavioral variation in prairie voles and other mammals”
From Oxytocin receptors modulate a social salience neural network in male prairie voles (2017) · cites this paper as Olazabal, 2014
In voles, OTR density in the nucleus accumbens (NAc) is associated with individual and species variation in social attachment behavior.
“In voles, OTR density in the nucleus accumbens (NAc)—a region important for social and reward learning—is associated with individual and species variation in social attachment behavior.”
From Oxytocin receptors modulate a social salience neural network in male prairie voles (2017) · cites this paper as Olazabal, 2014

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“Briefly, OXT and AVP have been proposed to facilitate parental behavior and pair bonding in females and males respectively (Carter et al., 1995; Wang et al., 2000; Young and Wang, 2004; see Ophir et al., 2012 for an excellent discussion on this topic).”
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Parental Behavior
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Introduction
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Development of the Parental Brain in Nonhuman Mammals
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Development of the Parental Brain in Humans
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Brain Mechanisms Regulating Maternal Behavior in Nonhuman Mammals
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.003.0004
Preface
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.002.0006
Copyright Page
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.002.0003
Abbreviations Used for Major Brain Regions
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.002.0007
Dedication
Numan, M. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190848675.002.0004

‘Cause I said so…
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Authors: Olazábal, D. E.
Affiliations: Universidad de la República de Uruguay (UY)
Corresponding author: Olazábal, Daniel E.
ORCID: Olazábal, Daniel E.
Venue: Journal of Physiology-Paris
Publisher: Elsevier BV
Published: 2014-04
Volume: 108
Issue: 2-3
Pages: 213-220
ISSN: 0928-4257 (ISSN-L)
DOI: 10.1016/j.jphysparis.2014.10.002
OpenAlex: W2028460559
Cited by: 35
References: 117
Citations by year: 2022: 2 · 2020: 17 · 2019: 5 · 2018: 2 · 2017: 3 · 2016: 5 · 2015: 1
FWCI: 4.45
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Physiology-Paris (publishedVersion)
PubMed (publishedVersion)
Funders: University of Illinois at Urbana-Champaign
Comisión Sectorial de Investigación Científica
Topics: Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
Social Sciences › Psychology › Social Psychology › Primate Behavior and Ecology
Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Behavior and Reproduction
Keywords: oxytocin receptor, nucleus accumbens, alloparental care, parental behavior, sex differences, male parental behavior, brain adaptation, social behavior, comparative neuroanatomy
MeSH terms: Animals, Animals, Newborn, Humans, Maternal Behavior, Nucleus Accumbens, Oxytocin, Paternal Behavior, Sex Characteristics, Social Behavior, Parenting, Receptors, Oxytocin

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Comparative analysis of oxytocin receptor density in the nucleus accumbens: an adaptation for female and male alloparental care?

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