Cited by 1,000Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on BehaviorDecision-Making and Behavioral Economics

The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.

Optimal decision making and the anterior cingulate cortex

Kennerley, Steven W, Walton, Mark E, Behrens, Timothy E J, Buckley, Mark J, Rushworth, Matthew F S·2006·Nature Neuroscience

DOI 10.1038/nn1724

Open this paper in CoChat — free account

Abstract

Learning the value of options in an uncertain environment is central to optimal decision making. The anterior cingulate cortex (ACC) has been implicated in using reinforcement information to control behavior. Here we demonstrate that the ACC's critical role in reinforcement-guided behavior is neither in detecting nor in correcting errors, but in guiding voluntary choices based on the history of actions and outcomes. ACC lesions did not impair the performance of monkeys (Macaca mulatta) immediately after errors, but made them unable to sustain rewarded responses in a reinforcement-guided choice task and to integrate risk and payoff in a dynamic foraging task. These data suggest that the ACC is essential for learning the value of actions.

Integrity signals

Registry

Crossref · 10.1038/nn1724

Cites

52 of 52 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Conflict monitoring and cognitive control
Botvinick, M. M., Braver, T. S., Barch, D. M., Carter, C. S., & Cohen, J. D. (2001) · Psychological Review · doi:10.1037/0033-295x.108.3.624 · Cited by 7,351
An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance
Aston-Jones, G., & Cohen, J. D. (2005) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.28.061604.135709 · Cited by 4,472
The neural basis of human error processing: Reinforcement learning, dopamine, and the error-related negativity.
Holroyd, C. B., & Coles, M. G. H. (2002) · Psychological Review · doi:10.1037/0033-295x.109.4.679 · Cited by 4,027
Inhibition and the right inferior frontal cortex
Aron, A. R., Robbins, T. W., & Poldrack, R. A. (2004) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2004.02.010 · Cited by 3,197
A neural system for error detection and compensation
Gehring, W. J., Goss, B., Coles, M. G. H., Meyer, D. E., & Donchin, E. (1993) · Psychological Science · doi:10.1111/j.1467-9280.1993.tb00586.x · Cited by 2,862
Getting formal with dopamine and reward
Schultz, W. (2002) · Neuron · doi:10.1016/s0896-6273(02)00967-4 · Cited by 2,574
Reinforcement learning
Barto, A. (1998) · IFAC Proceedings Volumes · doi:10.1016/s1474-6670(17)38315-5 · Cited by 2,172
Uncertainty, Neuromodulation, and Attention
Yu, A. J., & Dayan, P. (2005) · Neuron · doi:10.1016/j.neuron.2005.04.026 · Cited by 1,774
Primate anterior cingulate cortex: Where motor control, drive and cognition interface
Paus, T. (2001) · Nature Reviews Neuroscience · doi:10.1038/35077500 · Cited by 1,722
Neural correlates of decision variables in parietal cortex
Platt, M. L., & Glimcher, P. W. (1999) · Nature · doi:10.1038/22268 · Cited by 1,721

Show all 52 references

Sorted by citations

Items 201–300 of 1,000

Individual differences in reinforcement learning: Behavioral, electrophysiological, and neuroimaging correlates
Santesso, D. L., Dillon, D. G., Birk, J. L., Holmes, A. J., Davis, E., Bogdan, R., & Pizzagalli, D. A. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.05.032 · Cited by 136
Blunted Neural Responses to Reward in Remitted Major Depression: A High-Density Event-Related Potential Study
Whitton, A. E., Kakani, P., Foti, D., Veer, A. V., Haile, A., Crowley, D. J., & Pizzagalli, D. A. (2015) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2015.09.007 · Cited by 135
Intention, Choice, and the Medial Frontal Cortex
Rushworth, M. F. S. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1440.014 · Cited by 135
Self-citation
Single-Neuron Correlates of Error Monitoring and Post-Error Adjustments in Human Medial Frontal Cortex
Fu, Z., Wu, D.-A. J., Ross, I. B., Chung, J. M., Mamelak, A. N., Adolphs, R., & Rutishauser, U. (2018) · Neuron · doi:10.1016/j.neuron.2018.11.016 · Cited by 134
Multiple Representations of Belief States and Action Values in Corticobasal Ganglia Loops
Samejima, K., & Doya, K. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1390.024 · Cited by 131
Decision Threshold Modulation in the Human Brain
Domenech, P., & Dreher, J. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.2371-10.2010 · Cited by 131
Dopaminergic modulation of the exploration/exploitation trade-off in human decision-making
Chakroun, K., Mathar, D., Wiehler, A., Ganzer, F., & Peters, J. (2020) · eLife · doi:10.7554/elife.51260 · Cited by 131
The Relative Influences of Priors and Sensory Evidence on an Oculomotor Decision Variable During Perceptual Learning
Gold, J. I., Law, C.-T., Connolly, P. M., & Bennur, S. (2008) · Journal of Neurophysiology · doi:10.1152/jn.90629.2008 · Cited by 131
Cognitive impact of genetic variation of the serotonin transporter in primates is associated with differences in brain morphology rather than serotonin neurotransmission
Jedema, H. P., Gianaros, P. J., Greer, P. J., Kerr, D. D., Liu, S., Higley, J. D., Suomi, S. J., Olsen, A. S., Porter, J. N., Lopresti, B. J., et al. (2009) · Molecular Psychiatry · doi:10.1038/mp.2009.90 · Cited by 130
Prefrontal connectomics: From anatomy to human imaging
Haber, S. N., Liu, H., Seidlitz, J., & Bullmore, E. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-021-01156-6 · Cited by 129
Neural encoding of competitive effort in the anterior cingulate cortex
Hillman, K. L., & Bilkey, D. K. (2012) · Nature Neuroscience · doi:10.1038/nn.3187 · Cited by 129
Neural Basis of Motivational and Cognitive Control
Mars, R., Sallet, J., Mfs., R., & Yeung, N. (2011) · The MIT Press eBooks · doi:10.7551/mitpress/9780262016438.001.0001 · Cited by 128
Functional Specialization of the Primate Frontal Cortex during Decision Making: Figure 1.
Lee, D., Rushworth, M. F. S., Walton, M. E., Watanabe, M., & Sakagami, M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1561-07.2007 · Cited by 127
Self-citation
Lateral Intraparietal Cortex and Reinforcement Learning during a Mixed-Strategy Game
Seo, H., Barraclough, D. J., & Lee, D. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1479-09.2009 · Cited by 125
Contrasting reward signals in the orbitofrontal cortex and anterior cingulate cortex
Wallis, J. D., & Kennerley, S. W. (2011) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2011.06277.x · Cited by 125
Self-citation
Social rewards and social networks in the human brain
Fareri, D. S., & Delgado, M. R. (2014) · The Neuroscientist · doi:10.1177/1073858414521869 · Cited by 124
A Novel Neural Prediction Error Found in Anterior Cingulate Cortex Ensembles
Hyman, J. M., Holroyd, C. B., & Seamans, J. K. (2017) · Neuron · doi:10.1016/j.neuron.2017.06.021 · Cited by 124
Deciphering Decision Making: Variation in Animal Models of Effort- and Uncertainty-Based Choice Reveals Distinct Neural Circuitries Underlying Core Cognitive Processes
Winstanley, C. A., & Floresco, S. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1713-16.2016 · Cited by 123
Interbrain phase synchronization during turn‐taking verbal interaction—a hyperscanning study using simultaneous EEG/MEG
Ahn, S., Cho, H., Kwon, M., Kim, K., Kwon, H., Kim, B. S., Chang, W. S., Chang, J. W., & Jun, S. C. (2017) · Human Brain Mapping · doi:10.1002/hbm.23834 · Cited by 120
Grey matter abnormalities within cortico-limbic-striatal circuits in acute and weight-restored anorexia nervosa patients
Friederich, H.-C., Walther, S., Bendszus, M., Biller, A., Thomann, P., Zeigermann, S., Katus, T., Brunner, R., Zastrow, A., & Herzog, W. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2011.09.042 · Cited by 119
Hierarchical Error Representation: A Computational Model of Anterior Cingulate and Dorsolateral Prefrontal Cortex
Alexander, W. H., & Brown, J. W. (2015) · Neural Computation · doi:10.1162/neco_a_00779 · Cited by 119
Anterior Cingulate Cortex and the Control of Dynamic Behavior in Primates
Monosov, I. E., Haber, S. N., Leuthardt, E. C., & Jezzini, A. (2020) · Current Biology · doi:10.1016/j.cub.2020.10.009 · Cited by 118
Translational studies of goal-directed action as a framework for classifying deficits across psychiatric disorders
Griffiths, K. R., Morris, R. W., & Balleine, B. W. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00101 · Cited by 118
Right Ventromedial and Dorsolateral Prefrontal Cortices Mediate Adaptive Decisions under Ambiguity by Integrating Choice Utility and Outcome Evaluation
Christakou, A., Brammer, M. J., Giampietro, V., & Rubia, K. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1279-09.2009 · Cited by 118
A Parallel Functional Topography between Medial and Lateral Prefrontal Cortex: Evidence and Implications for Cognitive Control
Taren, A. A., Venkatraman, V., & Huettel, S. A. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.5762-10.2011 · Cited by 118
The Statistical Neuroanatomy of Frontal Networks in the Macaque
Averbeck, B. B., & Seo, M. (2008) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000050 · Cited by 118
A Long-Range Fronto-Parietal 5- to 10-Hz Network Predicts "Top-Down" Controlled Guidance in a Task-Switch Paradigm
Phillips, J. M., Vinck, M. A., Everling, S., & Womelsdorf, T. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht050 · Cited by 117
Two Anatomically and Computationally Distinct Learning Signals Predict Changes to Stimulus-Outcome Associations in Hippocampus
Boorman, E. D., Rajendran, V. G., O’Reilly, J. X., & Behrens, T. E. J. (2016) · Neuron · doi:10.1016/j.neuron.2016.02.014 · Cited by 116
Self-citation
Performance monitoring local field potentials in the medial frontal cortex of primates: anterior cingulate cortex
Emeric, E. E., Brown, J. W., Leslie, M., Pouget, P., Stuphorn, V., & Schall, J. D. (2008) · Journal of Neurophysiology · doi:10.1152/jn.00896.2006 · Cited by 114
Flexible combination of reward information across primates
Farashahi, S., Donahue, C. H., Hayden, B. Y., Lee, D., & Soltani, A. (2019) · Nature Human Behaviour · doi:10.1038/s41562-019-0714-3 · Cited by 112
Anterior cingulate neurons in the rat map anticipated effort and reward to their associated action sequences
Cowen, S. L., Davis, G. A., & Nitz, D. A. (2012) · Journal of Neurophysiology · doi:10.1152/jn.01012.2011 · Cited by 112
Debates on the dorsomedial prefrontal/dorsal anterior cingulate cortex: insights for future research
Clairis, N., & Lopez‐Persem, A. (2023) · Brain · doi:10.1093/brain/awad263 · Cited by 111
Economic Choice as an Untangling of Options into Actions
Yoo, S. B. M., & Hayden, B. Y. (2018) · Neuron · doi:10.1016/j.neuron.2018.06.038 · Cited by 110
(No) time for control: Frontal theta dynamics reveal the cost of temporally guided conflict anticipation
van Driel, J., Swart, J. C., Egner, T., Ridderinkhof, K. R., & Cohen, M. X. (2015) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-015-0367-2 · Cited by 110
The error‐related negativity is related to risk taking and empathy in young men
Santesso, D. L., & Segalowitz, S. J. (2008) · Psychophysiology · doi:10.1111/j.1469-8986.2008.00714.x · Cited by 110
The Anterior Cingulate Gyrus Signals the Net Value of Others' Rewards
Apps, M. A. J., & Ramnani, N. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.2701-13.2014 · Cited by 109
Neural Correlates of Novel Object and Novel Location Recognition Behavior in the Mouse Anterior Cingulate Cortex
Weible, A. P., Rowland, D. C., Pang, R. D., & Kentros, C. G. (2009) · Journal of Neurophysiology · doi:10.1152/jn.00214.2009 · Cited by 109
Encoding of reward and space during a working memory task in the orbitofrontal cortex and anterior cingulate sulcus
Kennerley, S. W., & Wallis, J. D. (2009) · Journal of Neurophysiology · doi:10.1152/jn.00273.2009 · Cited by 108
Self-citation
Increased neural responses to reward in adolescents and young adults with attention-deficit/hyperactivity disorder and their unaffected siblings
von Rhein, D., Cools, R., Zwiers, M. P., van der Schaaf, M., Franke, B., Luman, M., Oosterlaan, J., Heslenfeld, D. J., Hoekstra, P. J., Hartman, C. A., et al. (2015) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2015.02.012 · Cited by 108
A novel ecological account of prefrontal cortex functional development.
Werchan, D. M., & Amso, D. (2017) · Psychological Review · doi:10.1037/rev0000078 · Cited by 108
Adaptive coding of action values in the human rostral cingulate zone
Jocham, G., Neumann, J., Klein, T. A., Danielmeier, C., & Ullsperger, M. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0349-09.2009 · Cited by 106
Anterior cingulate cortex in schema assimilation and expression
Wang, S.-H., Tse, D., & Morris, R. G. M. (2012) · Learning & Memory · doi:10.1101/lm.026336.112 · Cited by 106
Metaplasticity as a Neural Substrate for Adaptive Learning and Choice under Uncertainty
Farashahi, S. G., Donahue, C. H., Khorsand, P., Seo, H., Lee, D., & Soltani, A. (2017) · Neuron · doi:10.1016/j.neuron.2017.03.044 · Cited by 106
Anterior cingulate cortex is necessary for adaptation of action plans
Brockett, A. T., Tennyson, S. S., deBettencourt, C. A., Gaye, F., & Roesch, M. R. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1919303117 · Cited by 106
Encoding of both positive and negative reward prediction errors by neurons of the primate lateral prefrontal cortex and caudate nucleus
Asaad, W. F., & Eskandar, E. N. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.3793-11.2011 · Cited by 105
Exploration Disrupts Choice-Predictive Signals and Alters Dynamics in Prefrontal Cortex
Ebitz, R. B., Albarran, E., & Moore, T. (2017) · Neuron · doi:10.1016/j.neuron.2017.12.007 · Cited by 105
Mesolimbic Dopamine Function Is Related to Salience Network Connectivity: An Integrative Positron Emission Tomography and Magnetic Resonance Study
McCutcheon, R. A., Nour, M. M., Dahoun, T., Jauhar, S., Pepper, F., Expert, P., Veronese, M., Adams, R. A., Turkheimer, F., Mehta, M. A., et al. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.09.010 · Cited by 104
Robot Cognitive Control with a Neurophysiologically Inspired Reinforcement Learning Model
Khamassi, M., Lallée, S., Enel, P., Procyk, E., & Dominey, P. F. (2011) · Frontiers in Neurorobotics · doi:10.3389/fnbot.2011.00001 · Cited by 104
Neural correlates of feedback processing in decision-making under risk
Schuermann, B., Endraß, T., & Kathmann, N. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00204 · Cited by 104
The Role of the Anterior Cingulate Cortex in Choices based on Reward Value and Reward Contingency
Chudasama, Y., Daniels, T. E., Gorrin, D. P., Rhodes, S. E. V., Rudebeck, P. H., & Murray, E. A. (2012) · Cerebral Cortex · doi:10.1093/cercor/bhs266 · Cited by 103
The Computation of Stimulus Values in Simple Choice
Rangel, A., & Clithero, J. A. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-416008-8.00008-5 · Cited by 102
Calculating the Cost of Acting in Frontal Cortex
Walton, M. E., Rudebeck, P. H., Bannerman, D. M., & Rushworth, M. F. S. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1390.009 · Cited by 102
Self-citation
Differential Effects of Amygdala, Orbital Prefrontal Cortex, and Prelimbic Cortex Lesions on Goal-Directed Behavior in Rhesus Macaques
Rhodes, S. E. V., & Murray, E. A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.4374-12.2013 · Cited by 99
Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Genetic Variation and Stress Interact to Influence Reward Learning
Bogdan, R., Santesso, D. L., Fagerness, J. A., Perlis, R. H., & Pizzagalli, D. A. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.2661-11.2011 · Cited by 99
Corticoinsular circuits encode subjective value expectation and violation for effortful goal-directed behavior
Arulpragasam, A. R., Cooper, J. A., Nuutinen, M. R., & Treadway, M. T. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1800444115 · Cited by 99
Segregated and Integrated Coding of Reward and Punishment in the Cingulate Cortex
Fujiwara, J., Tobler, P. N., Taira, M., Iijima, T., & Tsutsui, K. (2009) · Journal of Neurophysiology · doi:10.1152/jn.90909.2008 · Cited by 98
The tipping point: Value differences and parallel dorsal–ventral frontal circuits gating human approach–avoidance behavior
Schlund, M. W., Brewer, A. T., Magee, S. K., Richman, D. M., Solomon, S., Ludlum, M., & Dymond, S. (2016) · NeuroImage · doi:10.1016/j.neuroimage.2016.04.070 · Cited by 97
The differences in frontal midline theta power between successful and unsuccessful basketball free throws of elite basketball players
Chuang, L.-Y., Huang, C., & Hung, T. (2013) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2013.10.002 · Cited by 96
Performance monitoring following conflict: Internal adjustments in cognitive control?
Larson, M. J., Clayson, P. E., & Baldwin, S. A. (2012) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.12.021 · Cited by 96
Behavioral and Neural Valuation of Foods Is Driven by Implicit Knowledge of Caloric Content
Tang, D. W., Fellows, L. K., & Dagher, A. (2014) · Psychological Science · doi:10.1177/0956797614552081 · Cited by 96
Theoretical perspective on anorexia nervosa: The conflict of reward
Keating, C. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.07.004 · Cited by 95
Behavioral Regulation and the Modulation of Information Coding in the Lateral Prefrontal and Cingulate Cortex
Khamassi, M., Quilodran, R., Enel, P., Dominey, P. F., & Procyk, E. (2014) · Cerebral Cortex · doi:10.1093/cercor/bhu114 · Cited by 95
Deep brain stimulation of the dorsal anterior cingulate cortex for the treatment of chronic neuropathic pain
Russo, J. F., & Sheth, S. A. (2015) · Neurosurgical FOCUS · doi:10.3171/2015.3.focus1543 · Cited by 93
Strategic control in decision‐making under uncertainty
Venkatraman, V., & Huettel, S. A. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08009.x · Cited by 93
Reward-Guided Learning with and without Causal Attribution
Jocham, G., Brodersen, K. H., Constantinescu, A. O., Kahn, M. C., Ianni, A. M., Walton, M. E., Rushworth, M. F. S., & Behrens, T. E. J. (2016) · Neuron · doi:10.1016/j.neuron.2016.02.018 · Cited by 92
Self-citation
Acute alcohol intoxication impairs top–down regulation of Stroop incongruity as revealed by blood oxygen level- dependent functional magnetic resonance imaging.
Marinkovic, K., Rickenbacher, E., Azma, S., & Artsy, E. (2012) · Human Brain Mapping · doi:10.1002/hbm.21213 · Cited by 92
The Meaning of Embodiment
Kiverstein, J. D. (2012) · Topics in Cognitive Science · doi:10.1111/j.1756-8765.2012.01219.x · Cited by 92
A Basal Forebrain-Cingulate Circuit in Macaques Decides It Is Time to Act
Khalighinejad, N., Bongioanni, A., Verhagen, L., Folloni, D., Attali, D., Aubry, J.-F., Sallet, J., & Rushworth, M. F. S. (2020) · Neuron · doi:10.1016/j.neuron.2019.10.030 · Cited by 90
Self-citation
Monitoring demands for executive control: shared functions between human and nonhuman primates
Mansouri, F. A., Egner, T., & Buckley, M. J. (2017) · Trends in Neurosciences · doi:10.1016/j.tins.2016.11.001 · Cited by 89
Self-citation
Childhood trauma is associated with elevated anhedonia and altered core reward circuitry in major depression patients and controls
Fan, J., Liu, W., Xia, J., Li, S., Gao, F., Zhu, J., Han, Y., Zhou, H., Liao, H., Yi, J., et al. (2020) · Human Brain Mapping · doi:10.1002/hbm.25222 · Cited by 89
Error-specific medial cortical and subcortical activity during the stop signal task: A functional magnetic resonance imaging study
Li, C. R., Yan, P., Chao, H. H., Sinha, R., Paliwal, P., Constable, R. T., Zhang, S., & Lee, T.-W. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.06.062 · Cited by 89
Premotor and Motor Cortices Encode Reward
Ramkumar, P., Dekleva, B. M., Cooler, S., Miller, L. E., & Kording, K. P. (2016) · PLoS ONE · doi:10.1371/journal.pone.0160851 · Cited by 89
Cognitive Control as Cost‐Benefit Decision Making
Kool, W., Shenhav, A., & Botvinick, M. (2017) · Wiley eBooks · doi:10.1002/9781118920497.ch10 · Cited by 89
Dopamine and reward: a view from the prefrontal cortex
Chau, B. K. H., Jarvis, H., Law, C.-K., & Chong, T. T. ‐. (2018) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000424 · Cited by 88
Dynamic Encoding of Responses and Outcomes by Neurons in Medial Prefrontal Cortex
Luk, C.-H., & Wallis, J. D. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0386-09.2009 · Cited by 88
A dynamic code for economic object valuation in prefrontal cortex neurons
Tsutsui, K., Fabian Grabenhorst, B., Kobayashi, S., & Schultz, W. (2016) · Nature Communications · doi:10.1038/ncomms12554 · Cited by 87
Increased fronto-striatal reward prediction errors moderate decision making in obsessive–compulsive disorder
Hauser, T. U., Iannaccone, R., Dolan, R. J., Ball, J., Hättenschwiler, J., Drechsler, R., Rufer, M., Brandeis, D., Walitza, S., & Brem, S. (2017) · Psychological Medicine · doi:10.1017/s0033291716003305 · Cited by 86
Computational models of adaptive behavior and prefrontal cortex
Soltani, A., & Koechlin, É. (2021) · Neuropsychopharmacology · doi:10.1038/s41386-021-01123-1 · Cited by 86
Simultaneous representation of a spectrum of dynamically changing value estimates during decision making
Meder, D., Kolling, N., Verhagen, L., Wittmann, M. K., Scholl, J., Madsen, K. H., Hulme, O. J., Behrens, T. E. J., & Rushworth, M. F. S. (2017) · Nature Communications · doi:10.1038/s41467-017-02169-w · Cited by 86
Self-citation
Amygdala Contributions to Stimulus–Reward Encoding in the Macaque Medial and Orbital Frontal Cortex during Learning
Rudebeck, P. H., Ripple, J. A., Mitz, A. R., Averbeck, B. B., & Murray, E. A. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.0933-16.2017 · Cited by 85
Dynamical prefrontal population coding during defensive behaviours
Jercog, D., Winke, N., Sung, K., Martín‐Fernández, M., Francioni, C., Rajot, D., Courtin, J., Chaudun, F., Jercog, P. E., Valério, S., et al. (2021) · Nature · doi:10.1038/s41586-021-03726-6 · Cited by 85
Reduced Cortical Volume and Elevated Astrocyte Density in Rats Chronically Treated With Antipsychotic Drugs—Linking Magnetic Resonance Imaging Findings to Cellular Pathology
Vernon, A. C., Crum, W. R., Lerch, J. P., Chege, W., Natesan, S., Modo, M., Cooper, J. D., Williams, S., & Kapur, S. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.09.012 · Cited by 85
Normative development of ventral striatal resting state connectivity in humans
Fareri, D. S., Gabard-Durnam, L. J., Goff, B., Flannery, J., Gee, D. G., Lumian, D. S., Caldera, C., & Tottenham, N. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.06.022 · Cited by 85
Motivational Deficits in Schizophrenia and the Representation of Expected Value
Waltz, J. A., & Gold, J. M. (2015) · Current topics in behavioral neurosciences · doi:10.1007/7854_2015_385 · Cited by 84
Long-term intensive training induced brain structural changes in world class gymnasts
Huang, R., Lü, M., Song, Z., & Wang, J. (2013) · Brain Structure and Function · doi:10.1007/s00429-013-0677-5 · Cited by 84
Modulation of feedback related activity in the rostral anterior cingulate cortex during trial and error exploration
Amiez, C., Sallet, J., Procyk, E., & Petrides, M. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.06.023 · Cited by 84
Numerical Rule Coding in the Prefrontal, Premotor, and Posterior Parietal Cortices of Macaques
Vallentin, D., Bongard, S., & Nieder, A. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5071-11.2012 · Cited by 82
Efficient reinforcement learning: computational theories, neuroscience and robotics
Kawato, M., & Samejima, K. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.03.004 · Cited by 82
Temporal dynamics of reward processing revealed by magnetoencephalography
Doñamayor, N., Marco‐Pallarés, J., Heldmann, M., Schoenfeld, M. A., & Münte, T. F. (2011) · Human Brain Mapping · doi:10.1002/hbm.21184 · Cited by 82
Motivation to eat and not to eat – The psycho-biological conflict in anorexia nervosa
Frank, G., DeGuzman, M. C., & Shott, M. E. (2019) · Physiology & Behavior · doi:10.1016/j.physbeh.2019.04.007 · Cited by 81
Genetic modulation of cognitive flexibility and socioemotional behavior in rhesus monkeys
Izquierdo, A., Newman, T. K., Higley, J. D., & Murray, E. A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0706583104 · Cited by 81
Capturing the temporal evolution of choice across prefrontal cortex
Hunt, L. T., Behrens, T. E. J., Hosokawa, T., Wallis, J. D., & Kennerley, S. W. (2015) · eLife · doi:10.7554/elife.11945 · Cited by 81
Self-citation
Ramping ensemble activity in dorsal anterior cingulate neurons during persistent commitment to a decision
Blanchard, T. C., Strait, C. E., & Hayden, B. Y. (2015) · Journal of Neurophysiology · doi:10.1152/jn.00711.2015 · Cited by 80
Cell-Type-Specific Contributions of Medial Prefrontal Neurons to Flexible Behaviors
Nakayama, H., Ibáñez-Tallon, I., & Heintz, N. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.3537-17.2018 · Cited by 80
Synchronization of Medial Temporal Lobe and Prefrontal Rhythms in Human Decision Making
Guitart‐Masip, M., Barnes, G. R., Horner, A. J., Bauer, M., Dolan, R. J., & Düzel, E. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2573-12.2013 · Cited by 79
Control without Controllers: Toward a Distributed Neuroscience of Executive Control
Eisenreich, B. R., Akaishi, R., & Hayden, B. Y. (2017) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01139 · Cited by 79
Prefrontal cortex and cognitive control: new insights from human electrophysiology
Widge, A. S., Heilbronner, S. R., & Hayden, B. Y. (2019) · F1000Research · doi:10.12688/f1000research.20044.1 · Cited by 78
Neural Correlates of Abstract Verb Processing
Rodríguez‐Ferreiro, J., Gennari, S. P., Davies, R. A. I., & Cuetos, F. (2010) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2010.21414 · Cited by 78
Thalamocingulate Interactions In Performance Monitoring
Seifert, S., von Cramon, D. Y., Imperati, D., Tittgemeyer, M., & Ullsperger, M. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6242-10.2011 · Cited by 78
Neuropsychological disturbance in schizophrenia: A diffusion tensor imaging study.
Nestor, P. G., Kubicki, M. R., Niznikiewicz, M. A., Gurrera, R. J., McCarley, R. W., & Shenton, M. E. (2008) · Neuropsychology · doi:10.1037/0894-4105.22.2.246 · Cited by 78

Authors: Kennerley, S. W., Walton, M. E., Behrens, T. E. J., Buckley, M. J., & Rushworth, M. F. S.
Affiliations: University of Oxford (GB)
John Radcliffe Hospital (GB)
Corresponding author: Kennerley, Steven W
ORCID: Kennerley, Steven W
Walton, Mark E
Behrens, Timothy E J
Buckley, Mark J
Rushworth, Matthew F S
Venue: Nature Neuroscience
Publisher: Springer Science and Business Media LLC
Published: 2006-06-18
Volume: 9
Issue: 7
Pages: 940-947
ISSN: 1097-6256 (ISSN-L)
1546-1726
DOI: 10.1038/nn1724
OpenAlex: W2009639618
Cited by: 948
References: 52
Citations by year: 2026: 38 · 2025: 43 · 2024: 41 · 2023: 47 · 2022: 33 · 2021: 37 · 2020: 28 · 2019: 41 · 2018: 35 · 2017: 57 · 2016: 58 · 2015: 51 · 2014: 49 · 2013: 58 · 2012: 55
FWCI: 26.05
Type: journal article
Language: en
Open access: closed
Licence: www.springer.com/tdm (tdm)
Locations: Nature Neuroscience (publishedVersion)
PubMed (publishedVersion)
UCL Discovery (University College London) (submittedVersion)
Funders: Wellcome Trust
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
Keywords: anterior cingulate cortex, optimal decision making, reinforcement learning, value learning, error correction, error detection, voluntary choice, foraging behavior, lesion studies, macaque
MeSH terms: Animals, Behavior, Animal, Conditioning, Operant, Decision Making, Gyrus Cinguli, Macaca mulatta, Male, Probability Learning, Psychomotor Performance, Reinforcement, Psychology, Reinforcement Schedule

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Optimal decision making and the anterior cingulate cortex

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks