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Epigenetic modulators, modifiers and mediators in cancer aetiology and progression
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“However, persistent modifications can be achieved with dCas9 by fusing it to acetyltransferase, histone/DNA demethylase or methyltransferase, altering histone acetylation/methylation or DNA methylation marks and inducing potentially inheritable epigenetic expression modulation when dividing cells are targeted [78,79,80].”
From CRISPR-Cas: Converting A Bacterial Defence Mechanism into A State-of-the-Art Genetic Manipulation Tool (2019) · cites this paper as [80]
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Metadata
- Authors
- Feinberg, A. P., Koldobskiy, M. A., & Göndör, A.
- Venue
- Nature Reviews Genetics
- Published
- 2016-03-14
- Volume
- 17
- Issue
- 5
- Pages
- 284-299
- ISSN
- 1471-0056
- 1471-0064
- PMC
- PMC4888057
- Cited by
- 841
- References
- 41
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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