Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes

Wiviott, S. D., Raz, I., Bonaca, M. P., Mosenzon, O., Kato, E. T., Cahn, A., Silverman, M. G., Zelniker, T. A., Kuder, J. F., Murphy, S. A., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1812389 · Cited by 6,382

AMPK: guardian of metabolism and mitochondrial homeostasis

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A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

Ngandu, T., Lehtisalo, J., Solomon, A., Levälahti, E., Ahtiluoto, S., Antikainen, R., Bäckman, L., Hänninen, T., Jula, A., Laatikainen, T., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60461-5 · Cited by 3,689

The mechanisms of action of metformin

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Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

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Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

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Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

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Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy

Mercuri, E., Darras, B. T., Chiriboga, C. A., Day, J. W., Campbell, C., Connolly, A. M., Iannaccone, S. T., Kirschner, J., Kuntz, N. L., Saito, K., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1710504 · Cited by 1,433

Lactate in the brain: from metabolic end-product to signalling molecule

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Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease

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Additional file 24 of The hibernation-derived compound SUL-138 shifts the mitochondrial proteome towards fatty acid metabolism and prevents cognitive decline and amyloid plaque formation in an Alzheimer’s disease mouse model

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Succinate Confers Stronger Cytoprotection in Kidney Cells than in Astrocytes Due to Its More Efficient Involvement in Energy Metabolism

Buyan, M. I., Cherkesova, K. S., Brezgunova, A. A., Pevzner, I. B., Andrianova, N. V., & Plotnikov, E. Y. (2025) · Biochemistry (Moscow) · doi:10.1134/s0006297925602539

Mechanistic Pathways of Bioactive Phytocompounds in Neurodegenerative Disorders

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Nutritional Interventions for Dementia Prevention: A Brief Perspective

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Immunosenescence‐Driven Hemodynamic Dysregulation and Cognitive Impairment in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An Integrative Perspective

Xu, H., Luo, Y., & Wu, X. X. (2026) · Comprehensive physiology · doi:10.1002/cph4.70098 · Cited by 1

MR GENTLE—multicentre randomised controlled trial of ghrelin in anterior circulation ischaemic stroke treated with endovascular thrombectomy: a phase 2 trial

Omes, Q. P. M., van der Veen, D., Kersten, C. J. B. A., Arntz, R. M., Filius, P. M. G., van den Wijngaard, I. R., van der Worp, H. B., & Hofmeijer, J. (2026) · Trials · doi:10.1186/s13063-026-09426-8

Corilagin reduces ischemic stroke damage by neural stem cell-mediated neurorepair

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Alzheimer’s disease: diabetes of the brain

Moreira, P. I., Cardoso, S., & Perry, G. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-33841-0.00030-0

Characterizing the metabolomes of microglia, astrocytes, and neurons in aging and Alzheimer’s brainsPreprint

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The functional role of glial cells in the pathologic brain as reviewed by Alois Alzheimer in 1910

Kettenmann, H., Lassmann, H., Ugursu, B., & Xiang, X. (2026) · Molecular Neurodegeneration · doi:10.1186/s13024-026-00933-5

Dynamic PET Imaging of Elesclomol-Facilitated Copper Delivery in Ischemic Stroke Rats

Yuan, X., Zhang, Y., Huang, H., Xie, L., Hanyu, M., Chen, L., Cheng, W., Zhang, S., Kononov, A. I., Wang, R., et al. (2026) · ACS Omega · doi:10.1021/acsomega.5c10826

A decline in glycolytic ATP production is the fundamental mechanism limiting lifespan; species with an optimal rate of decline over time survived

Taguchi, A., Okinaka, Y., Claussen, C., & Gul, S. (2026) · Aging · doi:10.18632/aging.206356

Hericium erinaceus Extract Relieves Depression by Targeting the Microbiota–Metabolite–Neurotrophic Axis

Gong, P., Wang, J., Long, H., Wenjuan, Y. A. N. G., Chen, X., Wang, J., Li, N., Chen, F., & Guo, Y. (2026) · Journal of Future Foods · doi:10.1016/j.jfutfo.2026.03.014 · Cited by 1

Advances in Research on Cognitive Impairment of Parkinson’s Disease in High-Altitude Areas

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Energy Compensation Strategy: The Frontier of Neurodegenerative Disease Treatment

Tang, J., Sun, Y., Lin, X., Zhao, X., Mao, C., Wan, M., Li, J., & Guan, Y. (2026) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5c00964

One-month early time-restricted eating enhances cognition via white matter–cortical pathways in males with metabolic syndrome: evidence from TBSS and SBM analyses

Jin, X., Feng, L., Li, X., Qu, T., Wu, Y., Wang, Z., Hui, K., Guo, H., Chen, L., Wang, L., et al. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1753462 · Cited by 1

Metabolic reprogramming in Alzheimer’s disease: Interaction between receptor tyrosine kinase signaling, noncoding RNAs, and Neuron–Glia energy networks

Karmakar, A., Roycowdhury, P., Sengupta, P., & Mukhopadhyay, D. (2026) · International review of neurobiology · doi:10.1016/bs.irn.2026.02.007

Aging is not a disease: an evolutionary and comparative biological reappraisal

Feltes, B. C. (2026) · Biogerontology · doi:10.1007/s10522-026-10422-3 · Cited by 1

Protective effects of adenosine A2B receptor antagonism in a cuprizone-induced demyelination model

Cherchi, F., Venturini, M., Frulloni, L., Panozzi, F., Magni, G., Santalmasi, C., Maestrelli, C., Giovannini, M. G., Coppi, E., Lana, D., et al. (2026) · Neuropharmacology · doi:10.1016/j.neuropharm.2026.110944

Insulin resistance and ischemic stroke

Пизова, Н. В., & Pizov, A. V. (2026) · Russian neurological Journal · doi:10.30629/2658-7947-2025-30-6-4-10

Dietary Patterns and Cerebral Glucose Metabolism in Older Adults: Findings from the Western Australian Memory Study

Castro, C. B., Gardener, S. L., Jahan, F., Chen, J., Brown, B. M., Loo, R. L., Taddei, K., Rainey‐Smith, S. R., Weinborn, M., dos Reis, A. C. R., et al. (2026) · Nutrients · doi:10.3390/nu18071136

Study of vesicular glycolysis in health and Huntington's Disease

Cluskey, M. M. (2021) · theses.fr (ABES) · doi:10.70675/eb022640z9c3cz4467z940dz6b27765c296b

Cross-national dietary systems and dementia incidence: an ecological analysis of gluten-containing cereal protein supply

Feng, S., Endrawes, G., Henneberg, M., Wei, R., Garcia, L. R., & You, W. (2026) · Archives of Gerontology and Geriatrics Plus · doi:10.1016/j.aggp.2026.100273

Lactate, an underestimated molecule in nerve regeneration

Li, H., Ming, L., Tu, Z., Zhao, Y., Cheng, M., Zhang, Z., Gao, C., & Jiang, J. (2026) · Neurobiology of Disease · doi:10.1016/j.nbd.2026.107377

Ketogenic diet regulates Uch-L1(C) to improve cerebral energy metabolism and cognitive function in Alzheimer's disease mice

Bao, N., Zhang, M., Tang, M., Shen, Z., Wang, S., & Jiang, G. (2026) · European Journal of Histochemistry · doi:10.4081/ejh.2026.4548

Variants in glycine decarboxylase activate catabolic mechanisms of mitochondrial energy metabolism in the brain

Lopez‐Ramirez, A., Worth, A. J., Wang, Z. (., Yilmaz, S., Hayes, S., Tang, H., Farris, J. D., Alam†, M. S., Padmanabhan, P. K., & Haldar, K. (2026) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2026.113098

Genome-Wide CRISPR Screening Identifies Genetic Modulators of Amyloid Precursor Protein Processing

Li, Y., Yao, Y., Xu, Z., Xiong, Y., Zhang, C., Yu, L., Huiling, G., & Fei, T. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27093926

Total N-acetylaspartate: A potential early biomarker of depression?

Hudhud, L., Haney, M., Petrović, P., Stiernman, L. J., & Lindgren, L. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.121896

Combined Fish Oil and Pine Bark Extract Supplementation Improves Short-Term Memory and the Antioxidant Status in Middle-Aged and Older Adults with Mild Cognitive Impairment: A Randomized Double-Blind, Parallel-Group Pilot Study

Hsiao, T.-C., Hsu, C.-D., Xiao, Q., Chen, Y.-H., Piriou, Y., Shirakawa, H., & Yang, S. (2026) · Antioxidants · doi:10.3390/antiox15050588

Innovation in Dementia Prevention Driven by Health Checkup Data and XAI ―The Concept and Social Implementation of AICOG Based on the Brain–Body Axis Concept―

酒谷, 薫. (2026) · JAPANES JOURNAL OF MEDICAL INSTRUMENTATION · doi:10.4286/jjmi.96.66

Targeting microglia: A new strategy for the treatment of Alzheimer's disease

Zheng, M., Yang, M., Su, W., Tian, L., & Gao, W. (2026) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2026.578966

Synaptic health in brain disorders: Impact of nanoplastic exposure

Ijomone, O. K., Omotosho, O. I., Awoyemi, I. L., Ovwere, I. R., Okeowo, O. M., Oyeniran, D. A., Oyerinde, T. O., Anadu, V. E., Gbayisomore, T. J., & Ijomone, O. M. (2026) · Advances in neurotoxicology · doi:10.1016/bs.ant.2026.03.011

Odd-Chain Fatty Acids-Enriched Algal Oil Improves Locomotor Function and Modulates Metabolic Pathways in Caenorhabditis elegans Model of Alzheimer’s Disease

Mu, Q., Ma, Y., Zhang, T., Cong, F., Jin, J., Jin, Q., & Wang, X. (2026) · Molecules · doi:10.3390/molecules31101734

Trafficking of protein kinases to mitochondria: Implications for ischemic stroke

Pandya, C. D., Kunjadiya, A. P., Dalwadi, P., Singh, R., Khan, S. N., Pennypacker, K. R., Fraser, J. F., Stowe, A. M., & Sullivan, P. G. (2026) · Experimental Gerontology · doi:10.1016/j.exger.2026.113176

Investigation of Neurotransplantation and Regenerative Therapy in Preclinical Models

Sugaya, K. (2026) · Contemporary clinical neuroscience · doi:10.1007/978-3-032-18296-8_28

Liver-nervous system axis: pathways, dysregulation, and translational perspectives

Hao, D., Hu, Y., Luo, W., Li, S., Yan, Y., & Zhou, J. (2026) · Journal of Neuroinflammation · doi:10.1186/s12974-026-03875-3

Overexpression of hippocampal METTL3 mitigates chronic social isolation–induced abnormal behaviour in mice via modulation of mitochondrial-related proteins

Chen, J., Li, Y., Huo, X., Xie, J., Cao, W., Niu, L., 周翠兰, Zuo, L., & Xu, Y. (2026) · Behavioural Brain Research · doi:10.1016/j.bbr.2026.116293

Intermittent fasting and neuroprotection in Alzheimer’s disease: metabolic mechanisms, cellular signaling, and brain-peripheral crosstalk

Sudasinghe, K., & Hall, S. E. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1839995

Susceptibility to mild and severe acute mountain sickness is associated with distinct urine metabolite profiles

Sibomana, I., Beidleman, B. A., Karl, J. P., Figueiredo, P. S., Landspurg, S. D., Staab, J. E., & Mauzy, C. A. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1704360

Therapeutic targeting of brain bioenergetics in Alzheimer’s disease addressing insulin resistance, glucose hypometabolism, and mitochondrial dysfunction

Jangra, J., Mahindru, I., & Kumar, R. (2026) · International review of neurobiology · doi:10.1016/bs.irn.2026.05.005

Time‐Restricted Feeding Preserves Synaptic Function and Modulates Reelin and α ‐Synuclein in an Acute Amyloid‐ β Rat Model: A Comparative Study With Alternate‐Day Fasting

Maleki, Z., Mirshekar, M. A., Montazerifar, F., Etminani, B., & Keykha, F. (2026) · Journal of Nutrition and Metabolism · doi:10.1155/jnme/7185647

Metabolic Dysregulation in Traumatic Brain Injury: Mechanisms, Clinical Implications, and Therapeutic Opportunities

Ali, A., Hussain, M. S., Ahmed, M. E., Giri, S., & Ahmad, A. S. (2026) · Journal of Neurotrauma · doi:10.1177/08977151261452922

Dimethyl fumarate ameliorates quinolinic acid-induced ageing and neurodegeneration in Caenorhabditis elegans

Sun, Y., Zhou, K., Cui, J., Ding, H., Shareef, I., Du, L., Shi, Z., Fu, L., Sun, F., Zhu, Z., et al. (2026) · Biogerontology · doi:10.1007/s10522-026-10455-8

The effects of acute ketone monoester supplementation on brain insulin responsiveness and cognitive performance: Results of a randomized, double-blind, placebo-controlled crossover trial in older men with overweight

Nijssen, K. M. R., Adam, T. C., Mensink, R. P., & Joris, P. J. (2026) · Metabolism · doi:10.1016/j.metabol.2026.156672

Impact of sublethal concentrations of monosodium methylarsonate (MSMA) on zebrafish: Insights from embryotoxicity assessment and NMR-based metabolomics

Porto, V. A., da Rocha, E. R., da Silveira, F. F. C. L., Neto, J. H. S., Silva, D. L. F., Crispim, A. C., Ursulino, J. S., Costa, T. B. B. C., Bento, E. S., Santos, J. C. C., et al. (2026) · Environmental Pollution · doi:10.1016/j.envpol.2026.128581

A multi-organ spatial metabolomic atlas of exercising mice reveals neuronal Complex I as a convergent and sufficient axis for tau pathology reduction in PS19Preprint

Medina, T., Quiñones, S., Liu, Z., Wu, L., Ziani, B., Shedlock, C. J., Ma, X., Ryan, A., Larson, R., Soto, C. M., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.16.732673

Brain energy metabolism changes and neuropsychological impairment in Parkinson disease vs Alzheimer disease

Khodadadi, S., Rezaeimanesh, N., Motahar, A. A., Yousefi, F., Avateffazeli, M., Montazeri‐Shatouri, R., Hosseini, E., Negah, S. S., & Moghadasi, A. N. (2026) · International review of neurobiology · doi:10.1016/bs.irn.2026.06.001

ZBTB7A-mediated regulation of astrocytic glycolysis in neurodegenerative diseases: insights from literature review and bioinformatics prediction

Ye, P., Li, Z., Cui, X., Wu, H., & Jiang, H. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1852019

Sequential targeting nanochaperone disrupts positive feedback loop of mitochondrial dysfunction for Alzheimer's disease therapy

Hu, H., Zhao, S., Xu, L., Ma, Z., Ma, R., Huang, F., & Shi, L. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124408

Selective knockout of PKA regulatory subunits reveal opposite catalytic and metabolic consequences with implications for Alzheimer’s diseasePreprint

Rossitto, L.-A. M., Lu, T. W., Ma, Y., Sharma, P. K., Burghi, V., Gonzalez, C. G., Bruystens, J. G. H., Maurya, S. R., Wu, J., Lona, A., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.26.734839

Spatial metabolic fluxes reveal tissue metabolic heterogeneity by integrating mass spectrometry imaging and stable isotope tracing

Li, T., Zang, Q., Zhu, S., Tu, X., Li, X., Liu, J., Zhang, Y., & Zhang, R. (2026) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2026.101707

Japanese encephalitis virus hijacks the host purine biosynthetic network to promote viral replication in neurons

Gu, J., Fan, C., Xiang, S., Yang, L., Liu, J., Si, Y., Zhu, B., Sun, Y., Ding, C., Cao, S., et al. (2026) · PLoS Pathogens · doi:10.1371/journal.ppat.1014335

Huntington’s Disease as a Neuroglial Systems Disorder: Mechanisms, Network Propagation, and Therapeutic Opportunities

Pérez-Villavicencio, J., Villa-Robledo, O., Megchun-Vázquez, X., Uriarte-Jiménez, F., Rubio‐Osornio, M., & Serrano‐García, N. (2026) · Neuroglia · doi:10.3390/neuroglia7030023

Astrocytic lactate shuttle disruption and the energy-starved lysosome in Alzheimer's diseasePreprint

Kim¹, Y., Heo, W., Park, S. J., Kim, Y., & Cho², Y. E. (2026) · Research Square · doi:10.21203/rs.3.rs-10057949/v1

Leveraging Advanced AI Frameworks for Dual PPAR α/γ Agonist Discovery in Alzheimer’s Disease

Chaturvedi, N., Mishra, V., Haque, S., Khatoon, S., Rawal, K., & Kumar, V. (2026) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.6c00148

Rethinking frailty as a disorder of mitochondrial adaptability, from energetic congestion to systemic vulnerability

LORENZO, R. D., & Rovere, P. Q. (2026) · Pharmacological Research · doi:10.1016/j.phrs.2026.108345

Multimodal characterization of age-dependent susceptibility to high-cholesterol-diet-induced AD-like alterations in WHBE rabbits

Yin, N., Ding, H., Su, R., Chen, Y., Zhou, L., Tao, Y., Chen, H., Sun, Z., & Li, J. (2026) · Neurochemistry International · doi:10.1016/j.neuint.2026.106229

Innovations and Insights in Probiotics: Their Applications, Mechanisms, and Safety

Li, M., Yue, X., & Liu, Z. (2026) · Foods · doi:10.3390/foods15152594

Hyperpolarized 13C MRI uncovers early and progressive metabolic dysfunction in the hAPP-J20 mouse model of Alzheimer’s diseasePreprint

Vasilkovska, T., Page, L. M. L., Guglielmetti, C., Radoul, M., Li, H., Xiao, J. N., Gordon, J. W., Nakamura, K., & Chaumeil, M. M. (2026) · Research Square · doi:10.21203/rs.3.rs-10437814/v1

Direct energy consumption by inhibitory GABAA receptors: from synaptic mechanisms to network activity

Menzikov, S. A., Zaichenko, D. M., Московцев, А. А., Morozov, S. G., & Kubatiev, A. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1834375

Transaldolase 1 contributes to pentose phosphate pathway disruption and synaptic dysfunction in Alzheimer’s disease

Hu, X., Yu, Y., Luo, H., Li, J., Zhang, X., Wang, G., Li, J., Li, J., Chen, H., & Qiu, Y. (2026) · Translational Neurodegeneration · doi:10.1186/s40035-026-00567-z

Druggable Pathophysiologic Targets in Alzheimer Disease: From Amyloid and Tau to Biomarker-Guided Multimodal Therapy

Park, J. (2026) · Dementia and Neurocognitive Disorders · doi:10.12779/dnd.2026.25.3.152

Armillariella tabescens polysaccharide targets microglial glycolysis to alleviate sleep deprivation-induced neuroinflammation through the mTOR signaling pathway

Zhang, Y., Yang, S., Ran, S., Du, M., Chen, J., Cen, M., Gu, Y., Liao, J., Liu, Y., Zhang, R., et al. (2026) · Phytomedicine · doi:10.1016/j.phymed.2026.158687

Effect of Acute Ingestion of a Ketone Monoester on Psychomotor Vigilance During Acute Severe Hypoxia Exposure

McClure, T. S., Greene, S., Westfall, L. M., Kernagis, D., Egan, B., & Koutnik, A. P. (2026) · Military Medicine · doi:10.1093/milmed/usag123

Metabolic Vulnerability Indices and Alzheimer’s Disease Risk: A Prospective UK Biobank Study

Ding, G., Liu, Y., Zhao, Y., Li, Y., He, Y., He, Y., Chen, N., & Cui, J. (2026) · Journal of Nutrition · doi:10.1016/j.tjnut.2026.101777

Insulin Resistance: Current State of Knowledge and Clinical Implications—Toward a Better Diagnostic Framework and the Question of Its Disease Status

Rodzeń, Ł., Rodzeń, M., Dyńka, D., Łojko, D., Karakuła‐Juchnowicz, H., Kraszewski, S., Fazio, S., Unwin, D., & Bikman, B. T. (2026) · Nutrients · doi:10.3390/nu18162666

Tau-targeting pharmacological strategies in neurodegenerative disease

Zheng, H., & Zheng, J. (2026) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2026.07.008

The sleep-wake cycle: molecular mechanisms, disorders, and therapeutic targets in the context of energy metabolism

Li, J.-K., Wang, R., Meng, X.-Y., & Kang, J. (2026) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-026-02890-3

Exogenous lactate ameliorates Aβ-induced energy deficit and neurotoxicity with increased mitochondrial TCA cycle carbon flux in SH-SY5Y cells

Chang, Y., Kim, H., Kim, Y., Park, A., Nam, S., Banerjee, D. R., Hasenour, C. M., Young, J. D., Brooks, G. A., Wolfe, R. R., et al. (2026) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00268.2026

Total glucosides of paeony ameliorate cognitive impairment by promoting ketogenesis and modulating Glu-AMPAR signaling

Hu, G., Gong, S., Yan, S., Rong, L., Zhang, H., Wu, H., Yao, L., & Li, W. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119851

From HIV to SARS-CoV-2 associated neurological disorder (“HAND” to “SAND”): Viral infection as a “time-bomb“ for the aging brain

Millan, M. J. (2026) · Neuroscience Applied · doi:10.1016/j.nsa.2026.107024

A LITERATURE REVIEW OF SGLT2 INHIBITORS IMPACT ON MAJOR NEURODEGENERATIVE DISORDERS INCLUDING ALZHEIMER AND PARKINSON DISEASE

Jucha, J., Zając, D., Darasz, D., Łukawski, A., Slobozheniuk, L., Bieniak-Pentchev, M., Kaczorek, M., Machnik, K., Dziewięcka, O., & Ziębka, W. (2026) · International Journal of Innovative Technologies in Social Science · doi:10.31435/ijitss.3(51).2026.6010

Glycolytic Reprogramming in Parkinson's Disease: From Bioenergetic Crosstalk to Therapeutic Modulation

Yi, Y., Chen, C., He, Y., Yu-zhou, S., Cheng, R., Liu, M., Liu, Z., & Zhang, X. (2026) · Medicinal Research Reviews · doi:10.1002/med.70103

Roles of glycolytic and pyruvate metabolism enzymes in Alzheimer’s disease glycometabolic reprogramming and their therapeutic potential

Chen, M., Zuo, C., Li, R., Zhang, J., Yao, Z., Li, L., & Cheng, L. (2026) · Discover Neuroscience · doi:10.1186/s13064-026-00314-0

Erzhi Pill restores hippocampal energy metabolism and synaptic integrity via GSK3β to alleviate cognitive decline, with GPR30 involvement

Xue, H., Chen, D., Lin, X., Meng, X., Ren, Y., Xie, Y., Sun, X., Wu, X., & Zhang, N. (2026) · Journal of Radiation Research and Applied Sciences · doi:10.1016/j.jrras.2026.102662

Postbiotics as a therapeutic target in cognitive impairment: Exploring into molecular pathways and neuroprotective effects

Dipa, P., Neha, Mandal, S., & Aran, K. R. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103353

Effects of ketogenic diet on cognitive impairment in older adults: a systematic review and meta-analysis

Xi, L., Wan, J., Hua, Y., Guo, M., Du, J., Luo, X., & Yu, H. (2026) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2026.106409

Mitohormesis linking metabolic dysfunction and neurodegeneration: implications for dementia and therapeutic strategies

Otoda, T., Nakajima, H., & Takayama, T. (2026) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2026.1892506

Epigenomic Remodeling by Lipid Metabolism: A Cross-Disease Perspective on Cancer and Brain Disorders

Rafique, A., Farooq, A., Cho, C. E., & Bakovic, M. (2026) · Genes · doi:10.3390/genes17091134

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