Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes

Wiviott, S. D., Raz, I., Bonaca, M. P., Mosenzon, O., Kato, E. T., Cahn, A., Silverman, M. G., Zelniker, T. A., Kuder, J. F., Murphy, S. A., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1812389 · Cited by 6,382

AMPK: guardian of metabolism and mitochondrial homeostasis

Herzig, S., & Shaw, R. J. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.95 · Cited by 4,192

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

Ngandu, T., Lehtisalo, J., Solomon, A., Levälahti, E., Ahtiluoto, S., Antikainen, R., Bäckman, L., Hänninen, T., Jula, A., Laatikainen, T., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60461-5 · Cited by 3,689

The mechanisms of action of metformin

Rena, G., Hardie, D. G., & Pearson, E. R. (2017) · Diabetologia · doi:10.1007/s00125-017-4342-z · Cited by 2,287

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

Butterfield, D. A., & Halliwell, B. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0132-6 · Cited by 1,954

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

Arnold, S. E., Arvanitakis, Z., Macauley-Rambach, S. L., Koenig, A. M., Wang, H.-Y., Ahima, R. S., Craft, S., Gandy, S., Buettner, C., Stoeckel, L. E., et al. (2018) · Nature Reviews Neurology · doi:10.1038/nrneurol.2017.185 · Cited by 1,597

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

Deczkowska, A., Keren-Shaul, H., Weiner, A., Colonna, M., Schwartz, M., & Amit, I. (2018) · Cell · doi:10.1016/j.cell.2018.05.003 · Cited by 1,474

Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy

Mercuri, E., Darras, B. T., Chiriboga, C. A., Day, J. W., Campbell, C., Connolly, A. M., Iannaccone, S. T., Kirschner, J., Kuntz, N. L., Saito, K., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1710504 · Cited by 1,433

Lactate in the brain: from metabolic end-product to signalling molecule

Magistretti, P. J., & Allaman, I. (2018) · Nature Reviews Neuroscience · doi:10.1038/nrn.2018.19 · Cited by 1,298

Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease

Kivipelto, M., Mangialasche, F., & Ngandu, T. (2018) · Nature Reviews Neurology · doi:10.1038/s41582-018-0070-3 · Cited by 1,173

Amyloid-ID: photocatalytic profiling of amyloid deposits in Alzheimer’s disease tissue

Feng, H., Zhao, Q., Guo, F., Yan, J., Zhao, N., Ma, J., Sun, R. X., Shen, K., Ge, Y., Zhang, X., et al. (2026) · Nature Communications · doi:10.1038/s41467-025-68017-4 · Cited by 7

What Are the Roles of Mitochondrial Stress Responses and Mitohormesis in Neurodegenerative Disorders?

Benarroch, E. E. (2026) · Neurology · doi:10.1212/wnl.0000000000214618 · Cited by 6

Transcranial Photobiomodulation for Neuromodulation of Brain Disorders: A Perspective

Ridder, D. D., Hamblin, M. R., & Vanneste, S. (2026) · Neuromodulation Technology at the Neural Interface · doi:10.1016/j.neurom.2025.12.006 · Cited by 5

Redox therapy for neuropsychiatric disorders: Molecular mechanisms and biomarker development

Cuklanz, K., Stein, A., Chouinard, V., Öngür, D., & Du, F. (2026) · Science Advances · doi:10.1126/sciadv.aea9014 · Cited by 5

Baseline FDG-PET Brain hypometabolism as a predictive biomarker of cognitive decline and Alzheimer’s disease risk

Alhasan, A. S., Alhasan, M. S., Milburn, J. M., Ghunaim, H. A., Khalil, M., Almaghraby, A., Alharthi, O. A., Hamoud, S., Essibayi, M. A., Elhassan, Y. H., et al. (2026) · The journal of nutrition health & aging · doi:10.1016/j.jnha.2026.100823 · Cited by 4

Anti-aging effects of low-molecular-weight polysaccharide PSP-1-1 from steamed Polygonatum sibiricum via gut microbiota modulation

Zhang, C., Lin, H., Wei, C., Long, X., Bai, S., Wu, H., Li, X., Zhou, Y., Li, S., Gao, Y., et al. (2026) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2026.125225 · Cited by 5

UBQLN2 links proteotoxicity with lipid metabolism in neurodegeneration

Liu, Y., Huang, Z., hsu, Y.-W., Deme, P., Frankenfield, A. M., Wu, S., Zhao, X., Liu, H., Zhang, T., Alexander, E. J., et al. (2026) · Nature Neuroscience · doi:10.1038/s41593-026-02226-y · Cited by 4

Targeting Lipid Metabolism in Alzheimer’s Disease: Emerging Insights and Future Directions

Balakrishnan, J., Kannan, S., Shanmugam, K., & Dhavamani, S. (2026) · Journal of Integrative Neuroscience · doi:10.31083/jin48436 · Cited by 4

Altered metabolic function induced by Aβ‐oligomers and PSEN1 mutations in iPSC ‐derived astrocytes

Elsworthy, R. J., Finelli, M. J., Aqattan, S., Dunleavy, C., King, M. C., Ludlam, A., Tarczyluk, M. A., Allen, S., Prosser, S., Chen, R., et al. (2024) · Journal of Neurochemistry · doi:10.1111/jnc.16267 · Cited by 7

A Self‐Reinforced “Microglia Energy Modulator” for Synergistic Amyloid‐β Clearance in Alzheimer's Disease Model

Ma, M., Wang, J., Guo, K., Zhong, W., Cheng, Y., Lin, L., & Zhao, Y. (2024) · Angewandte Chemie · doi:10.1002/ange.202420547 · Cited by 4

Affinity‐Based Protein Profiling Reveals IDH2 as a Mitochondrial Target of Cannabinol in Receptor‐Independent Neuroprotection

Schaller, E., Lamer, S., Schlösser, A., Stigloher, C., Maher, P. A., & Decker, M. W. (2025) · Chemistry - A European Journal · doi:10.1002/chem.202501143 · Cited by 4

Cardiometabolic state links neurovascular burden with brain structure and function: Evidence from EEG and MRI

Franco-O’Byrne, D., Laguardia, A. M. C., Delgado, C., Shine, J. M., Huepe, D., González-Gómez, R., Tagliazucchi, E., Gonzalez-Campo, C., Ibáñez, A. M., & Medel, V. (2025) · NeuroImage · doi:10.1016/j.neuroimage.2025.121308 · Cited by 4

Exploring Potential Causal Links: How Parkinson’s Disease Brain Damage Impacts Liver Health–A Mendelian Randomization and Transcriptomic Study

Liu, T., Chen, Q., Wu, H., Li, J., Xian, M., Lu, K., Zhu, C., & Wei, J. (2025) · Journal of Inflammation Research · doi:10.2147/jir.s511645 · Cited by 4

FGF21 restores metabolic function in Alzheimer’s disease via activation of PI3K/Akt signaling

Zhao, F., Yang, H., Liu, H., Yu, H., & Zhao, Y. (2025) · Neurological Research · doi:10.1080/01616412.2025.2521721 · Cited by 4

Comparison of Brain Oxygen Metabolic Parameters Between Constrained qBOLD and Whole‐Brain Oximetric Methods at Baseline and in Response to a Physiologic Stimulus

Jaroszynski, K. M., Lee, H., Langham, M. C., & Wehrli, F. W. (2025) · NMR in Biomedicine · doi:10.1002/nbm.70120 · Cited by 4

Spatial2GWAS: a database for linking spatial transcriptomic regions with GWAS traits

Hu, X., Wang, A., Yu, H., Kim, P., & Zhou, X. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf1047 · Cited by 5

The molecular mechanisms of cuproptosis and its role in central nervous system diseases

Xu, M., An, Y., Liu, X., Li, X., Huang, X., Gu, Q., Xue, M., Xue, J., Tao, L., Shan, H., et al. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.112236 · Cited by 5

SIRT3/AMPK-Driven Mitophagy Failure Underlies Methylmercury-Induced Neurotoxicity: Evidence from Humans to Cells

Hu, J., Zhang, L., Chen, F., Tian, C. L., Zhang, A., & Wang, W. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05576-z · Cited by 4

Regulation of Membrane Phospholipid Homeostasis in Neurodegenerative Diseases

Quan, X., & Bakovic, M. (2021) · OBM Geriatrics · doi:10.21926/obm.geriatr.2103176 · Cited by 4

Multi-nutrient interventions and cognitive ageing: are we barking up the right tree?

Young, H. A., Geurts, L., Scarmeas, N., Benton, D., Brennan, L., Farrimond, J. A., Kiliaan, A. J., Pooler, A. M., Trovò, L., Sijben, J., et al. (2022) · Nutrition Research Reviews · doi:10.1017/s095442242200018x · Cited by 4

Sculptor and Destroyer

Mattson, M. P. (2023) · The MIT Press eBooks · doi:10.7551/mitpress/14422.001.0001 · Cited by 4

Exhaustive exercise decreases tau phosphorylation and modifies biological processes associated with the protein translation and electron transport chain in P301L tau transgenic mice

He, K., Nie, L., Yang, C., Liu, Z., Huang, X., Li, S., & Yang, X. (2024) · Experimental Gerontology · doi:10.1016/j.exger.2024.112375 · Cited by 4

The Different Molecular Targets and Its Significant Role in Alzheimer’s Disease: A Review

Perumal, D. P., & Pichaivel, M. (2024) · Asian Journal of Medicine and Biomedicine · doi:10.37231/ajmb.2024.8.1.650 · Cited by 4

Impaired Mitochondrial Energy Metabolism Regulated by p70S6K: A Putative Pathological Feature in Alzheimer’s Disease

Gu, W., Cong, X., Pei, Y., Ajuyo, N. M. C., Min, Y., & Wang, D. (2024) · Metabolites · doi:10.3390/metabo14070369 · Cited by 4

Cognitive Benefits of Folic Acid, Docosahexaenoic Acid, and a Combination of Both Nutrients in Mild Cognitive Impairment: Possible Alterations through Mitochondrial Function and DNA Damage

Li, M., Li, T., Tong, Y., Huang, L., Zhao, J., Liu, H., Chen, Y., Li, W., Zhu, Y., Ma, F., et al. (2024) · Gerontology · doi:10.1159/000540021 · Cited by 6

Mapping Age Differences in Brain Energy Metabolites and Metabolic Markers of Cellular Membrane Production and Degradation With 31P Magnetic Resonance Spectroscopy

Raz, N., Daugherty, A. M., Khatib, D., Dahle, C. L., Rajan, U., Zajac‐Benitez, C., & Stanley, J. A. (2024) · Human Brain Mapping · doi:10.1002/hbm.70039 · Cited by 4

Lipoprotein Lipase and Neurological Health: Investigating its Impact on Brain Function and Alzheimer's Disease

Althaher, A. R., & S. AL Shehadeh, R. (2024) · The Open Biomarkers Journal · doi:10.2174/0118753183367402241216115139 · Cited by 4

A2-Astrocyte Activation by Short-Term Hypoxia Rescues α-Synuclein Pre-Formed-Fibril-Induced Neuronal Cell Death

Choi, H. N., Kim, S., Jo, M. G., Lee, B., Kim, Y. J., Lee, S. E., Lee, J. H., Seong, H., Kim, S.-J., Park, S. W., et al. (2025) · Biomedicines · doi:10.3390/biomedicines13030604 · Cited by 4

Mitochondrial proteostasis and cellular health: insights from chaperones and autophagy

Jagtap, Y. A., Choudhary, A., Kinger, S., Kumar, P., Bhattacharyya, S., Jha, H. C., Dhiman, R., Sharma, V., Suresh, A. K., Poluri, K. M., et al. (2025) · The Journal of Physiology · doi:10.1113/jp287635 · Cited by 4

Succinic acid-based biodegradable hydrogels drive Bv2 microglial polarization by ATP metabolism

Zhao, J., Xiong, Y., Wang, X., Wang, Y., He, J. H., & Wu, F. (2025) · Composites Part B Engineering · doi:10.1016/j.compositesb.2025.112383 · Cited by 4

The hallmarks of aging

Gilmour, B. C., Bergersen, L. H., & Fang, E. F. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91617-2.00007-9 · Cited by 4

Triheptanoin, an odd-medium-chain triglyceride, impacts brain cognitive function in young and aged mice

da Rocha, L. S., Mendes, C. B., Silva, J. S., Alcides, R. L. G. F., Mendonça, I. P., Andrade-da-Costa, B. L. S., Machado, S. S., & Ximenes-da-Silva, A. (2023) · Nutritional Neuroscience · doi:10.1080/1028415x.2023.2178096 · Cited by 4

Cardiorenal ketone metabolism: a positron emission tomography study in healthy humans

Cuenoud, B. M., Croteau, É., St‐Pierre, V., Richard, G. M., Fortier, M., Vandenberghe, C., Carpentier, A. C., & Cunnane, S. C. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1280191 · Cited by 4

Integrative Metabolomics and Whole Transcriptome Sequencing Reveal Role for TREM2 in Metabolism Homeostasis in Alzheimer’s Disease

Wang, M., Wei, T., Yu, C., Li, R., Yin, Y., Yang, H.-C., Di, R., Xia, X., Qin, Q., & Tang, Y. (2023) · Molecular Neurobiology · doi:10.1007/s12035-023-03840-8 · Cited by 6

The Clinical Use of Hydrogen as a Medical Treatment

Xie, Y., & Song, G. (2024) · Advances in biochemistry in health and disease · doi:10.1007/978-3-031-47375-3_6 · Cited by 4

The Effects of Ketogenic Diet on Brain Gene Expressions in Type 2 Diabetes Background

Ren, Q., Fu, J., Duan, X., Sun, L., Mu, Z., Liang, W., Li, Y., Wang, Z., & Xiu, S. (2024) · Neuroscience · doi:10.1016/j.neuroscience.2024.04.008 · Cited by 4

The Promise of a Golden Era for Exploring the Frontiers of Aging, Metabolism and Redox Biology

Zhang, J. (2020) · Frontiers in Aging · doi:10.3389/fragi.2020.610406 · Cited by 4

Role of Mitochondrial Heat-shock Proteins and Immunophilins in Neuro Degenerative Diseases

Daneri-Becerra, C., Ciucci, S. M., Mazaira, G. I., & Galigniana, M. D. (2021) · Current Drug Targets · doi:10.2174/1389450121999201230204320 · Cited by 5

Fueling Alzheimer’s Disease: Where Does Immunometabolism Stand?

Correia, S. C., Perry, G. L., & Moreira, P. I. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-240787 · Cited by 3

Homeostasis to Allostasis: Prefrontal Astrocyte Roles in Cognitive Flexibility and Stress Biology

Wulaer, B., Holtz, M., & Nagai, J. (2024) · Advances in neurobiology · doi:10.1007/978-3-031-64839-7_6 · Cited by 4

Molecular neuroimaging of ovarian steroid effects on the female brain: A systematic review of human non-clinical studies

Walsh, M. J. M., Gibson, K., Gray, R., McNeal, M., Lynch, L. S., Kang, M., Brierley, J. D., Bondy, E., Dichter, G. S., & Schiller, C. E. (2025) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x251348865 · Cited by 3

Association of Metformin with the Risk of Dementia: A Population-Based Retrospective Cohort Study in Taiwan

Hou, Z., Chou, Y., Yang, T., & Sun, C. (2025) · Healthcare · doi:10.3390/healthcare13131537 · Cited by 3

Facilitating microglial phagocytosis by which Jiawei Xionggui Decoction alleviates cognitive impairment via TREM2-mediated energy metabolic reprogramming

Wen, W., Chen, J., Xiang, J., Zhang, S., Liu, J., Wang, J., Wang, P., & Xu, S. (2025) · Chinese Journal of Natural Medicines · doi:10.1016/s1875-5364(25)60927-7 · Cited by 3

Repurposing the hypoglycaemic agents for neuroinflammation, a comprehensive review

Blossom, V., Ullal, S. D., Rai, R., souza, M. M. D., Kalluraya, P. G. G., Dixit, A., Jiji, P. J., & Murlimanju, B. V. (2025) · 3 Biotech · doi:10.1007/s13205-025-04455-7 · Cited by 3

Hierarchical Amorphous–Crystalline Ceramic Nanotube Array Nanocomposites with Superior Mechanical and Functional Properties

Chen, K., Hou, J., Ding, L., Wang, Q., Huang, Y., Xiao, Z., Liu, Z., Tang, X., Wu, Y., Zeng, Q., et al. (2025) · Advanced Materials · doi:10.1002/adma.202513101 · Cited by 3

The relationship between oral frailty and cognitive function in elderly patients with chronic diseases: the chain-mediated effect of nutrition status and the inflammatory marker CRP

Sun, Y., Zhang, Z., Wang, S., Yang, X., Li, Q., Lu, C., & Wang, G. (2025) · BMC Geriatrics · doi:10.1186/s12877-025-06374-x · Cited by 3

Medium-chain triglycerides and ketogenic diet prevent alterations of the gut microbiome in transgenic Alzheimer’s disease mice

M’Bra, P. E. H., Suárez-Uribe, I., Avino, M., Lim, E. N. K., Mayhue, M., Balthazar, P., Aumont, A., Prévost, K., Massé, É., & Fernandes, K. J. L. (2025) · Communications Biology · doi:10.1038/s42003-025-09171-9 · Cited by 3

GLUT1-DS Brain Organoids Exhibit Increased Sensitivity to Metabolic and Pharmacological Induction of Epileptiform Activity

Lengacher, L., Lengacher, S., Magistretti, P. J., & Finsterwald, C. (2026) · Pharmaceuticals · doi:10.3390/ph19010105 · Cited by 3

IL-27, a metabolic regulator secreted by astrocytes in response to GLP-1RA OHP2, modulates microglial reprogramming in Alzheimer’s disease by regulating cGAS lactylation

Du, Y., Wu, L., Mao, Y., Chen, S., & Gao, X. (2026) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03683-1 · Cited by 4

Histone lactylation leads to perioperative neurocognitive disorders by promoting the expression of Ralbp1 and inducing excessive mitochondrial fission in hippocampal neurons

Meng, F., Cao, S., Wu, W.-F., Zhang, M., Jing, Q., Xie, Z., Sun, X., Song, J., Fei, M., QIAN Cunyuan, C. G., et al. (2026) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-026-06095-3 · Cited by 3

Glial lactate metabolism and transport in Alzheimer’s disease

Wang, Y., Feng, B., Hong, R., Qiu, D., Zhao, J., & Zhao, L. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1731089 · Cited by 3

Perivascular fibroblasts at the nexus of CNS immunity

Verdon, M., Skipness, V., Häusle, L., & Pikor, N. B. (2026) · The Journal of Immunology · doi:10.1093/jimmun/vkag003 · Cited by 3

Bioactive hydroxyl-terminated phosphorus dendrimers mediate protein/drug co-delivery for enhanced multi-target ischemic stroke therapy

Cui, M., Zhang, C., Zou, Y., Qiu, M., Xia, J., Mignani, S. M., Majoral, J., Shen, M., & Shi, X. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124169 · Cited by 3

The effect of exogenous ketone bodies on cognition across health and disease: a systematic review and meta-analysis

Bonnechère, B., Stephens, E. B., Boileau, A. C., Ducker, M., & Stubbs, B. J. (2026) · Frontiers in Nutrition · doi:10.3389/fnut.2026.1802531 · Cited by 3

The multifaceted role of mitochondrial dysfunction in Alzheimer’s disease pathogenesis

Ebrahimi, R., Mohammadi, I., Ghafourian, K., Firouzabadi, S. R., Saleh, M., Davoody, S., Azad, G., & Esmaeilpour, K. (2026) · Metabolic Brain Disease · doi:10.1007/s11011-026-01850-8 · Cited by 4

The Interplay Between Immunometabolism and Neuroinflammation in Alzheimer’s Disease

Crescenzo, T. D., Papiri, G., Membrino, V., Alia, S., Cecati, M., Campagna, R., Silvestrini, M., Luzzi, S., & Vignini, A. (2026) · Biomolecules · doi:10.3390/biom16050656 · Cited by 3

Metabolic Reprogramming of Microglia in Neuroinflammation and Depression

Wu, Q., Tian, J., Gu, Y., Bi, X., & Zhang, H. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27093984 · Cited by 3

A ketogenesis-ferroptosis axis maintains leukemic stem cell survival and leukemia progression

Han, X., Wang, K., Ma, W., Zhu, S., Guan, J., Tian, X., Zhao, Z., & Jiang, L. (2026) · Cell stem cell · doi:10.1016/j.stem.2026.04.013 · Cited by 3

Ketogenic diet as a therapeutic strategy for neurodegenerative diseases: from mechanisms to translational challenges

Salgueiro, A. M., Ferreira‐Marques, M., Ribeiro, R. F. N., Lopes, S. M., Pereira, D., Costa, D. G., Santana, M. M., de Almeida, L. P., & Cavadas, C. (2026) · Translational Neurodegeneration · doi:10.1186/s40035-026-00557-1 · Cited by 4

[ 18 F]FDG functional PET revisited: A new perspective on the temporal dynamics of brain glucose metabolism

Hahn, A., Falb, P., Murgaš, M., Klug, S., Reed, M. B., Godbersen, G. M., de León, M. P., Milz, C., Hacker, M., Rujescu, D., et al. (2026) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x261455750 · Cited by 4

Omics-driven strategies for identifying biomarkers in Alzheimer’s disease

Khan, Y., Rekha, A., Ballal, S., Maharana, L., Maqbool, M., Goyal, K., Mishra, R., Uniyal, P., Alam, P., Aljarba, T. M., et al. (2026) · Metabolic Brain Disease · doi:10.1007/s11011-026-01873-1 · Cited by 3

Mitochondria and brain aging: From cell-specific dysfunction to intercellular cooperation

Grimm, A., Lang, U. E., & Eckert, A. (2026) · Neuron · doi:10.1016/j.neuron.2026.04.048 · Cited by 4

Hormetic Stress Responses in Aging: From Molecular Mechanisms to Clinical Translation

Ferreira, J. M. A., & Тукаєв, С. (2026) · Stresses · doi:10.3390/stresses6030055 · Cited by 4

Ldlr-/-.Leiden mice develop neurodegeneration, age-dependent astrogliosis and obesity-induced changes in microglia immunophenotype which are partly reversed by complement component 5 neutralizing antibody

Seidel, F., Fluiter, K., Kleemann, R., Worms, N., van Nieuwkoop, A., Caspers, M. P. M., Grigoriadis, N., Kiliaan, A. J., Baas, F., Michailidou, I., et al. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1205261 · Cited by 3

J24335 exerts neuroprotective effects against 6-hydroxydopamine-induced lesions in PC12 cells and mice

Pan, Z., Shao, M., Zhao, C., Yang, X., Li, H., Cui, G., Liang, X., Yu, C., Ye, Q., Cheng, G., et al. (2024) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2024.106696 · Cited by 3

Growth Differentiation Factor-15 Is Considered a Predictive Biomarker of Long COVID in Non-hospitalized Patients

Ono, R., Takayama, S., Abe, M., Arita, R., Abe, T., & Ishii, T. (2024) · Cureus · doi:10.7759/cureus.59433 · Cited by 3

Combination of RNA-seq and proteomics reveals the mechanism of DL0410 treatment in APP/PS1 transgenic mouse model of Alzheimer's disease

Zhang, B., Zhao, J., Yan, C., Bai, Y., Guo, P., Wang, C., Wang, Z., Du, G., & Liu, A. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116940 · Cited by 3

Cyanidin 3- O - β -galactoside from black chokeberry exerts neuroprotective effects in mice fed with high-fat/high-sugar diet through regulating glucose metabolism

Fan, Z., Liu, X., Gao, W., Zhang, L., Yang, X., & Li, J. (2024) · Food Science and Human Wellness · doi:10.26599/fshw.2024.9250275 · Cited by 3

Unveiling FOXO3's metabolic contribution to menopause and Alzheimer's disease

O'Mahony, C., Hidalgo‐Lanussa, O., & Barreto, G. E. (2025) · Experimental Gerontology · doi:10.1016/j.exger.2025.112679 · Cited by 3

Exploring Human Brain Metabolism via Genome-Scale Metabolic Modeling with Highlights on Multiple Sclerosis

Sertbaş, M., & Ülgen, K. Ö. (2025) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5c00006 · Cited by 5

Gastrodin inhibits hexokinase-2 mediated glycolysis to rescue rotenone-damaged PC12 cells

Chen, M., Tian, J., Jia, B., Wang, M., Han, A., Zhu, J., Tian, S., Gao, X., Li, B., Li, Q., et al. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04348-9 · Cited by 4

Constraint-based modeling of bioenergetic differences between synaptic and non-synaptic components of dopaminergic neurons in Parkinson’s disease

Luo, X., Assal, D. C. E., Liu, Y., Ranjbar, S., & Fleming, R. M. T. (2025) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2025.1594330 · Cited by 3

3-Hydroxybutyrate, a metabolite in sustaining neuronal cell vitality: a mendelian randomization and in vitro experimentation

Hu, X., Lin, Y. W., Huang, K., Xu, H., Fu, C. H., Ou, J., Fan, X., Li, Z., Fang, J., & Fang, S. (2025) · Nutrition & Metabolism · doi:10.1186/s12986-025-00960-x · Cited by 3

Mitochondrial Dysfunction in Neurodegenerative Diseases

Chen, C., Zhao, Y., Wang, J., Pan, D., Wang, X., Xu, Y., Yan, J., Wang, L., Yang, X., Lu, M., et al. (2025) · MedComm · doi:10.1002/mco2.70326 · Cited by 3

Mini-review: Processed red meat intake and risk of neurodegenerative diseases

Chen, K.-Q., Cao, W.-J., Liu, Z., & Liu, R.-Z. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1663647 · Cited by 3

Mitochondrial dysfunction, a new marker warning of neuropsychiatric disorder risk: evidence from genetics and epidemiology

Fu, Q., Li, J., Zhu, H., Yu, Q., Shen, T., Liu, Z., Liu, Y., & Zhou, W. P. (2025) · Annals of General Psychiatry · doi:10.1186/s12991-025-00604-7 · Cited by 3

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