Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes

Wiviott, S. D., Raz, I., Bonaca, M. P., Mosenzon, O., Kato, E. T., Cahn, A., Silverman, M. G., Zelniker, T. A., Kuder, J. F., Murphy, S. A., et al. (2019) · New England Journal of Medicine · doi:10.1056/nejmoa1812389 · Cited by 6,382

AMPK: guardian of metabolism and mitochondrial homeostasis

Herzig, S., & Shaw, R. J. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.95 · Cited by 4,192

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

Ngandu, T., Lehtisalo, J., Solomon, A., Levälahti, E., Ahtiluoto, S., Antikainen, R., Bäckman, L., Hänninen, T., Jula, A., Laatikainen, T., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(15)60461-5 · Cited by 3,689

The mechanisms of action of metformin

Rena, G., Hardie, D. G., & Pearson, E. R. (2017) · Diabetologia · doi:10.1007/s00125-017-4342-z · Cited by 2,287

Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease

Butterfield, D. A., & Halliwell, B. (2019) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0132-6 · Cited by 1,954

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

Arnold, S. E., Arvanitakis, Z., Macauley-Rambach, S. L., Koenig, A. M., Wang, H.-Y., Ahima, R. S., Craft, S., Gandy, S., Buettner, C., Stoeckel, L. E., et al. (2018) · Nature Reviews Neurology · doi:10.1038/nrneurol.2017.185 · Cited by 1,597

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

Deczkowska, A., Keren-Shaul, H., Weiner, A., Colonna, M., Schwartz, M., & Amit, I. (2018) · Cell · doi:10.1016/j.cell.2018.05.003 · Cited by 1,474

Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy

Mercuri, E., Darras, B. T., Chiriboga, C. A., Day, J. W., Campbell, C., Connolly, A. M., Iannaccone, S. T., Kirschner, J., Kuntz, N. L., Saito, K., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1710504 · Cited by 1,433

Lactate in the brain: from metabolic end-product to signalling molecule

Magistretti, P. J., & Allaman, I. (2018) · Nature Reviews Neuroscience · doi:10.1038/nrn.2018.19 · Cited by 1,298

Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease

Kivipelto, M., Mangialasche, F., & Ngandu, T. (2018) · Nature Reviews Neurology · doi:10.1038/s41582-018-0070-3 · Cited by 1,173

Dietary ketosis improves circadian dysfunction as well as motor symptoms in the BACHD mouse model of Huntington’s disease

Whittaker, D. S., Tamai, K., Bains, R. S., Villanueva, S. A. M. B., Luk, S. H. C., Dell’Angelica, D., Block, G. D., Ghiani, C. A., & Colwell, C. S. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1034743 · Cited by 22

Multifunctional nanomedicine strategies to manage brain diseases

Faria, P. D. P., Pacheco, C., Moura, R. P., Sarmento, B. F. C. C., & Martins, C. (2022) · Drug Delivery and Translational Research · doi:10.1007/s13346-022-01256-w · Cited by 22

PRKAA1 induces aberrant mitophagy in a PINK1/Parkin-dependent manner, contributing to fluoride-induced developmental neurotoxicity

Tang, Y., Zhang, J., Hu, Z., Xu, W., Xu, P., Ma, Y., Xing, H., & Niu, Q. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.114772 · Cited by 20

Insulin Resistance and Impaired Branched-Chain Amino Acid Metabolism in Alzheimer’s Disease

Liu, R., Zhang, L., & You, H. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-221147 · Cited by 19

Hypoxia‐sensing VGLL4 promotes LDHA‐driven lactate production to ameliorate neuronal dysfunction in a cellular model relevant to Alzheimer's disease

Tian, Q., Li, J., Wu, B., Wang, J., Xiao, Q., Tian, N., Yi, L., Luo, M., Li, Z., Pang, Y., et al. (2023) · The FASEB Journal · doi:10.1096/fj.202301173rrr · Cited by 20

Mitochondrial Targeting against Alzheimer’s Disease: Lessons from Hibernation

Mestdagh, C. F. D. V., Smit, A. B., Henning, R. H., & van Kesteren, R. E. (2023) · Cells · doi:10.3390/cells13010012 · Cited by 20

Ghrelin for Neuroprotection in Post–Cardiac Arrest Coma

Nutma, S., Beishuizen, A., van den Bergh, W. M., Foudraine, N. A., le Feber, J., Filius, P. M. G., Cornet, A. D., van der Palen, J. A. M., van Putten, M. J. A. M., Hofmeijer, J., et al. (2024) · JAMA Neurology · doi:10.1001/jamaneurol.2024.1088 · Cited by 20

Repurposing of Omarigliptin as a Neuroprotective Agent Based on Docking with A2A Adenosine and AChE Receptors, Brain GLP-1 Response and Its Brain/Plasma Concentration Ratio after 28 Days Multiple Doses in Rats Using LC-MS/MS

Ayoub, B. M., Michel, H. E., Mowaka, S., Hendy, M. S., & Tadros, M. M. (2021) · Molecules · doi:10.3390/molecules26040889 · Cited by 20

Astrocytes modulate brain phosphate homeostasis via polarized distribution of phosphate uptake transporter PiT2 and exporter XPR1

Cheng, X., Zhao, M., Chen, L., Huang, C., Xu, Q., Shao, J., Wang, H., Zhang, Y., Li, X., Xu, X., et al. (2024) · Neuron · doi:10.1016/j.neuron.2024.06.020 · Cited by 21

A comparative study of goji berry and ashwagandha extracts effects on promoting neural stem cell proliferation and reducing neuronal cell death

Zhang, Y.-M., & Wang, G. (2024) · Food & medicine homology. · doi:10.26599/fmh.2025.9420039 · Cited by 20

Adaptogens in Long-Lasting Brain Fatigue: An Insight from Systems Biology and Network Pharmacology

Panossian, A., Lemerond, T., & Efferth, T. (2025) · Pharmaceuticals · doi:10.3390/ph18020261 · Cited by 24

Inhibition of α‐Synuclein Accumulation Improves Neuronal Apoptosis and Delayed Postoperative Cognitive Recovery in Aged Mice

Li, Y., Yuan, Y., Li, Y., Han, D., Liu, T., Yang, N., Mi, X., Hong, J., Liu, K., Song, Y., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/5572899 · Cited by 19

Intranasal 15d-PGJ2 ameliorates brain glucose hypometabolism via PPARγ-dependent activation of PGC-1α/GLUT4 signalling in APP/PS1 transgenic mice

Li, Z., Zhang, Y., Zheng, Y., Liu, W., Zhang, X., Li, W., Zhang, D., Cai, Q., Wang, S., Meng, X., et al. (2021) · Neuropharmacology · doi:10.1016/j.neuropharm.2021.108685 · Cited by 19

The microRNA-455 Null Mouse Has Memory Deficit and Increased Anxiety, Targeting Key Genes Involved in Alzheimer’s Disease

Swingler, T. E., Niu, L., Pontifex, M. G., Vauzour, D., & Clark, I. M. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23010554 · Cited by 19

Mitochondrial SIRT3 Deficiency Results in Neuronal Network Hyperexcitability, Accelerates Age-Related Aβ Pathology, and Renders Neurons Vulnerable to Aβ Toxicity

Perone, I., Ghena, N., Wang, J., Mackey, C. D., Wan, R., Malla, S., Gorospe, M., Cheng, A., & Mattson, M. P. (2022) · NeuroMolecular Medicine · doi:10.1007/s12017-022-08713-2 · Cited by 20

Gas Chromatography–Mass Spectrometry (GC–MS) Metabolites Analysis in Endometriosis Patients: A Prospective Observational Translational Study

Angioni, S. L., Congiu, F., Vitale, S. G., D’Alterio, M. N., Noto, A., Monni, G., Santoru, M. L., Fanos, V., Murgia, F., & Atzori, L. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12030922 · Cited by 19

Bioinspired nanoerythrocytes for metabolic microenvironment remodeling and long-term prognosis promoting of acute ischemic stroke

Liu, P., Zhang, T., Li, C., Zhang, Y., Zhou, Z., Zhao, Z., Chen, Q., Sun, T., & Jiang, C. (2023) · Nano Today · doi:10.1016/j.nantod.2023.101806 · Cited by 19

Cerebrospinal Fluid sTREM-2, GFAP, and β-S100 in Symptomatic Sporadic Alzheimer’s Disease: Microglial, Astrocytic, and APOE Contributions Along the Alzheimer’s Disease Continuum

Bonomi, C. G., Assogna, M., Donna, M. G. D., Bernocchi, F., Lucia, V. D., Nuccetelli, M., Fiorelli, D., Loizzo, S., Mercuri, N. B., Koch, G., et al. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-221010 · Cited by 20

Dysregulation of Insulin-Linked Metabolic Pathways in Alzheimer’s Disease: Co-Factor Role of Apolipoprotein E ɛ 4

Robbins, J., Busquets, O., Tong, M., & de la Monte, S. M. (2020) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-200238 · Cited by 19

A novel PDHK inhibitor restored cognitive dysfunction and limited neurodegeneration without affecting amyloid pathology in 5xFAD mouse, a model of Alzheimer’s disease

Sakimura, K., Kawai, T., Nashida, R., Ishida, Y., Harada, K., Suzuki, T., Okuma, C., & Cole, G. M. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01552-2 · Cited by 18

H4K12 Lactylation Activated‐ Spp1 in Reprogrammed Microglia Improves Functional Recovery After Spinal Cord Injury

Wang, X., Zhou, G., Xiong, J., Wu, Y., Gao, Y., Wang, H., Pan, D., Luo, Y., & Zhou, Z. (2025) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70232 · Cited by 19

Challenges and opportunities in next-generation LED therapeutic devices

Wang, C., Yu, Q., Li, M., Chen, H., Fan, H., Ma, Y., Zhang, Z., Wu, M. X., & Lu, M. (2025) · Light Science & Applications · doi:10.1038/s41377-025-01990-z · Cited by 24

SGLT-2 Inhibitors in the Prevention and Progression of Neurodegenerative Diseases: A Narrative Review

Kostrzewska, P., Kuca, P., Witek, P., Małyszko, J., Madetko‐Alster, N., & Alster, P. (2025) · Neurology and Therapy · doi:10.1007/s40120-025-00832-9 · Cited by 20

Nuclear and Mitochondrial Genome, Epigenome and Gut Microbiome: Emerging Molecular Biomarkers for Parkinson’s Disease

Cabral, G. F., Schaan, A. P., Cavalcante, G. C., Sena-dos-Santos, C., de Souza, T. P., Port’s, N. M. D. S., Pinheiro, J. A. D. S., Ribeiro‐dos‐Santos, Â., & Vidal, A. F. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189839 · Cited by 18

Dietary factors and brain health

Lefèvre‐Arbogast, S., Thomas, A., & Samieri, C. (2021) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000803 · Cited by 18

A novel natural PPARγ agonist, Gypenoside LXXV, ameliorates cognitive deficits by enhancing brain glucose uptake via the activation of Akt/GLUT4 signaling in db/db mice

Meng, X., Zhang, Y., Li, Z., Hu, J., Zhang, D., Cao, W., Li, M., Ma, G., Wang, S., Cui, P., et al. (2022) · Phytotherapy Research · doi:10.1002/ptr.7413 · Cited by 18

Influence of Cerebral Glucose Metabolism by Chronic Pain–Mediated Cognitive Impairment in Adolescent Rats

Fang, Y., Chen, C., Zhong, Q., Wang, L., Gui, Z., Zhu, J., Manyande, A., Xu, F., Wang, J., & Zhang, Z. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-02816-4 · Cited by 17

Role of Semaphorins in Ischemic Stroke

Du, H., Xu, Y., & Zhu, L. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.848506 · Cited by 19

Study on the neuroprotective effect of Zhimu-Huangbo extract on mitochondrial dysfunction in HT22 cells induced by D-galactose by promoting mitochondrial autophagy

Ao, X., Zhao, D., Zhao, C., Li, X., Meng, Y., Zhao, H., Zhao, C., Lei, X., Wu, J., & Zhang, N. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.117012 · Cited by 18

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

Hagihara, H., Shoji, H., Hattori, S., Sala, G., Takamiya, Y., Tanaka, M., Ihara, M., Shibutani, M., Hatada, I., Hori, K., et al. (2023) · eLife · doi:10.7554/elife.89376 · Cited by 53

Efficacy and mechanism study of Baichanting compound, a combination of Acanthopanax senticosus (Rupr. and Maxim.) Harms, Paeonia lactiflora Pall and Uncaria rhynchophylla (Miq.) Miq. ex Havil, on Parkinson's disease based on metagenomics and metabolomics

Lu, Y., Gao, X., Mohammed, S. A. D., Wang, T., Fu, J., Yang, N., Yang, N., Liu, S., & Liu, S. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.117182 · Cited by 19

Tau: More than a microtubule‐binding protein in neurons

Alonso, A. D. C., Idrissi, A. E., Candia, R. F., Morozova, V., & Kleiman, F. E. (2023) · Cytoskeleton · doi:10.1002/cm.21795 · Cited by 17

Is metabolic-healthy obesity associated with risk of dementia? An age-stratified analysis of the Whitehall II cohort study

Machado‐Fragua, M. D., Sabia, S., Fayossé, A., Hassen, C. B., van der Heide, F. C. T., Mika Kivimaki, B., & Singh‐Manoux, A. (2023) · BMC Medicine · doi:10.1186/s12916-023-03155-4 · Cited by 18

Aging-associated weakening of the action potential in fast-spiking interneurons in the human neocortex

Szegedi, V., Tiszlavicz, Á., Furdan, S., Douida, A., Bakos, E., Barzó, P., Tamás, G., Szűcs, A. L., & Lamsa, K. P. (2024) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2024.04.020 · Cited by 18

Effects of Habitat River Microbiome on the Symbiotic Microbiota and Multi-Organ Gene Expression of Captive-Bred Chinese Giant Salamander

Zhu, W., Zhao, C., Feng, J., Chang, J., Zhu, W., Chang, L., Liu, J., Xie, F., Li, C., Jiang, J., et al. (2022) · Frontiers in Microbiology · doi:10.3389/fmicb.2022.884880 · Cited by 18

Myelin lipids as nervous system energy reservesPreprint

Asadollahi, E., Trevisiol, A., Saab, A. S., Looser, Z. J., Dibaj, P., Kusch, K., Ruhwedel, T., Möbius, W., Jahn, O., Baes, M. I., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.02.24.481621 · Cited by 18

Microglial SLC25A28 Deficiency Ameliorates the Brain Injury After Intracerebral Hemorrhage in Mice by Restricting Aerobic Glycolysis

Han, R., Liu, L., Wang, Y., Wu, R., Yang, Y. L., Zhao, Y., Jian, L., Yuan, Y., Zhang, L., Gu, Y., et al. (2023) · Inflammation · doi:10.1007/s10753-023-01931-1 · Cited by 17

The interplay between epitranscriptomic RNA modifications and neurodegenerative disorders: Mechanistic insights and potential therapeutic strategies

Hashmi, M. A. T. S., Fatima, H., Ahmad, S., Rehman, A., & Safdar, F. (2024) · Ibrain · doi:10.1002/ibra.12183 · Cited by 18

Hypoxia-triggered O-GlcNAcylation in the brain drives the glutamate–glutamine cycle and reduces sensitivity to sevoflurane in mice

He, Q., Yang, M. G., Huang, J. L., Wu, W., Tang, K., Zhang, Y., Zhou, J., Ou, W., Xie, M., Liang, Y., et al. (2022) · British Journal of Anaesthesia · doi:10.1016/j.bja.2022.06.041 · Cited by 18

Alzheimer’s Disease from the Amyloidogenic Theory to the Puzzling Crossroads between Vascular, Metabolic and Energetic Maladaptive Plasticity

Cerasuolo, M., Papa, M., Colangelo, A. M., & Rizzo, M. R. (2023) · Biomedicines · doi:10.3390/biomedicines11030861 · Cited by 18

Transcending the amyloid-beta dominance paradigm in Alzheimer's disease: An exploration of behavioural, metabolic, and gut microbiota phenotypes in 5xFAD mice

Vera, D. M., Zambrana-Infantes, E. N., López-Gambero, A. J., Verheul-Campos, J., Santín, L. J., Baixerás, E., Suárez, J., Pavón, F. J., Rosell‐Valle, C., & de Fonseca, F. R. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106295 · Cited by 17

Intermittent fasting and Alzheimer's disease—Targeting ketone bodies as a potential strategy for brain energy rescue

Ye, Y., Chai, S.-F., Li, X.-R., Wu, M., Cai, H.-Y., & Wang, Z.-J. (2023) · Metabolic Brain Disease · doi:10.1007/s11011-023-01288-2 · Cited by 18

Modulation of Mitochondrial Function as a Therapeutic Strategy for Neurodegenerative Diseases

Trushina, E. V., Nguyen, T. K. O., & Trushin, S. (2023) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2023.108 · Cited by 17

Potential neuroprotective and autophagy-enhancing effects of alogliptin on lithium/pilocarpine-induced seizures in rats: Targeting the AMPK/SIRT1/Nrf2 axis

El-Sayed, S. S., Ali, S. O., & Ibrahim, W. W. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122917 · Cited by 18

Ketone monoester attenuates declines in cognitive performance and oxygen saturation during acute severe hypoxic exposure under resting conditions

McClure, T. S., Phillips, J., Koutnik, A. P., Coleman, K., Chappe, E., Cutter, G., Egan, B., Norell, T., Stubbs, B. J., Bamman, M. M., et al. (2024) · Experimental Physiology · doi:10.1113/ep091794 · Cited by 17

Energy partitioning in the cell cortex

Chen, S., Seara, D. S., Michaud, A., Kim, S., Bement, W. M., & Murrell, M. P. (2024) · Nature Physics · doi:10.1038/s41567-024-02626-6 · Cited by 17

A Self‐Reinforced “Microglia Energy Modulator” for Synergistic Amyloid‐β Clearance in Alzheimer's Disease Model

Ma, M., Wang, J., Guo, K., Zhong, W., Cheng, Y., Lin, L., & Zhao, Y. (2024) · Angewandte Chemie International Edition · doi:10.1002/anie.202420547 · Cited by 18

NLRP3 Inflammasome Activation and Altered Mitophagy Are Key Pathways in Inclusion Body Myositis

Naddaf, E., Nguyen, T. K. O., Watzlawik, J. O., Gao, H., Hou, X., Fiesel, F. C., Mandrekar, J. N., Kokesh, E., Harmsen, W. S., Lanza, I. R., et al. (2024) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.13672 · Cited by 17

Brain network and energy imbalance in Parkinson’s disease: linking ATP reduction and α-synuclein pathology

Watanabe, H., Shima, S., Kawabata, K., Mizutani, Y., Ueda, A., & Ito, M. (2025) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2024.1507033 · Cited by 19

Ultra-stable dextran conjugated prodrug micelles for oxidative stress and glycometabolic abnormality combination treatment of Alzheimer's disease

Zhang, B., Gao, Y., Zhang, X., Jiang, J., Ren, J., Wang, S., Hu, H., Zhao, Y., Chen, L., Zhao, K., et al. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.01.154 · Cited by 17

Shared metabolic shifts in endothelial cells in stroke and Alzheimer’s disease revealed by integrated analysis

Guo, G., Fan, L., Yan, Y., Xu, Y., Deng, Z., Tian, M., Geng, Y., Xia, Z., & Xu, Y. (2023) · Scientific Data · doi:10.1038/s41597-023-02512-5 · Cited by 18

Pluripotent stem-cell-based screening uncovers sildenafil as a mitochondrial disease therapy

Zink, A., Dai, D., Wittich, A., Henke, M., Pedrotti, G., Heiduschka, S., Santamaria, G., Pentimalli, T. M., Brueser, C., Notopoulou, S., et al. (2026) · Cell · doi:10.1016/j.cell.2026.02.008 · Cited by 22

Restoration of Sarco/Endoplasmic Reticulum Ca2+-ATPase Activity Functions as a Pivotal Therapeutic Target of Anti-Glutamate-Induced Excitotoxicity to Attenuate Endoplasmic Reticulum Ca2+ Depletion

Zhang, W., Ye, F., Pang, N., Kessi, M., Xiong, J., Chen, S., Peng, J., Yang, L., & Yin, F. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.877175 · Cited by 16

KAMPOmics: A framework for multidisciplinary and comprehensive research on Japanese traditional medicine

Yamamoto, M. (2022) · Gene · doi:10.1016/j.gene.2022.146555 · Cited by 16

Leptin‐based hexamers facilitate memory and prevent amyloid‐driven AMPA receptor internalisation and neuronal degeneration

Doherty, G. H., Holiday, A., Malekizadeh, Y., Manolescu, C., Duncan, S., Flewitt, I., Hamilton, K., MacLeod, B., Ainge, J. A., & Harvey, J. (2022) · Journal of Neurochemistry · doi:10.1111/jnc.15733 · Cited by 16

Effects of Qi-Fu-Yin on aging of APP/PS1 transgenic mice by regulating the intestinal microbiome

Xiao, Q., Ye, T., Wang, X., Qi, D., & Cheng, X. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.1048513 · Cited by 17

MCT-Induced Ketosis and Fiber in Rheumatoid Arthritis (MIKARA)—Study Protocol and Primary Endpoint Results of the Double-Blind Randomized Controlled Intervention Study Indicating Effects on Disease Activity in RA Patients

Heidt, C., Pons‐Kühnemann, J., Kämmerer, U., Marquardt, T., & Reuss-Borst, M. A. (2023) · Nutrients · doi:10.3390/nu15173719 · Cited by 17

Neuroenergetic alterations in neurodegenerative diseases: A systematic review and meta-analysis of in vivo 31P-MRS studies

Jing, Y., Haeger, A., Boumezbeur, F., Binkofski, F., Reetz, K., & Romanzetti, S. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102488 · Cited by 16

Induced Expression of kir6.2 in A1 Astrocytes Propagates Inflammatory Neurodegeneration via Drp1-dependent Mitochondrial Fission

Song, N., Zhu, H. Y., Xu, R. H., Liu, J., Fang, Y., Zhang, J., Ding, J., Hu, G., & Lu, M. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.618992 · Cited by 16

Dynamic Interplay between Copper Toxicity and Mitochondrial Dysfunction in Alzheimer’s Disease

Tassone, G., Kola, A., Valensin, D., & Pozzi, C. (2021) · Life · doi:10.3390/life11050386 · Cited by 16

Plasma extracellular vesicles from recurrent GBMs carrying LDHA to activate glioblastoma stemness by enhancing glycolysis

Zhang, X., Li, J., Huang, Y., Yang, A., Liu, X., Luo, Y., Tian, H., Wen, M., Zhong, C., Peng, B., et al. (2025) · Theranostics · doi:10.7150/thno.102014 · Cited by 15

Development of perivascular astrocyte processes

Cohen‐Salmon, M., Guille, N., & Boulay, A.-C. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1585340 · Cited by 17

Unveiling the anti-senescence effects and senescence-associated secretory phenotype (SASP) inhibitory mechanisms of Scutellaria baicalensis Georgi in low glucose-induced astrocytes based on boolean network

Gao, L., Yang, W.-Y., Qi, H., Sun, C.-J., Qin, X., & Du, G. (2022) · Phytomedicine · doi:10.1016/j.phymed.2022.153990 · Cited by 15

Increasing brain glucose uptake by Gypenoside LXXV ameliorates cognitive deficits in a mouse model of diabetic Alzheimer's disease

Meng, X., Zhang, Y., Li, Z., Ma, G., Zhang, X., Zhang, D., Cao, W., Wang, S., Cai, Q., Cui, P., et al. (2022) · Phytotherapy Research · doi:10.1002/ptr.7639 · Cited by 15

The hibernation-derived compound SUL-138 shifts the mitochondrial proteome towards fatty acid metabolism and prevents cognitive decline and amyloid plaque formation in an Alzheimer’s disease mouse model

Mestdagh, C. F. D. V., Koopmans, F., Breiter, J. C., Timmerman, J. A., Vogelaar, P. C., Krenning, G., Mansvelder, H. D., Smit, A. B., Henning, R. H., & van Kesteren, R. E. (2022) · Alzheimer s Research & Therapy · doi:10.1186/s13195-022-01127-z · Cited by 15

Supplementation of Medium-Chain Triglycerides Combined with Docosahexaenoic Acid Inhibits Amyloid Beta Protein Deposition by Improving Brain Glucose Metabolism in APP/PS1 Mice

Wang, Z., Zhang, D., Cheng, C., Lin, Z., Zhou, D., Sun, Y., Li, W., Yan, J., Luo, S., Qian, Z., et al. (2023) · Nutrients · doi:10.3390/nu15194244 · Cited by 16

Alteration of Metabolic Profiles during the Progression of Alzheimer’s Disease

Yu, W., Chen, L., Li, X., Han, T.-L., Yang, Y., Hu, C., Yu, W., & Lü, Y. (2023) · Brain Sciences · doi:10.3390/brainsci13101459 · Cited by 15

Sensor‐integrated brain‐on‐a‐chip platforms: Improving the predictive validity in neurodegenerative research

Spitz, S., Schobesberger, S., Brandauer, K., & Ertl, P. (2023) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10604 · Cited by 17

SERS Immunoassay Based on an Enzyme-Catalyzed Cascade Reaction and Metal–Organic Framework/Alkaline Phosphatase for Ultrasensitive Detection of Adenosine Triphosphate

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