Cited by 174Tryptophan and brain disordersStress Responses and CortisolTreatment of Major Depression

Cytokines and depression: fortuitous or causative association?

Dantzer, R, Wollman, E, Vitkovic, L, Yirmiya, R·1999·Molecular Psychiatry

Abstract

There is an increasingly impressive database concerning the possible involvement of cytokines in depression and their role in the therapeutic effects of antidepressants. Based on the discussions which took place on these issues at a recent meeting held in Roscoff, France, this perspective summarizes in a critical way the evidence in favor of such a possibility, and points out the needs for further research to clarify both the nature of the subtle dysregulations that affect neuroendocrine-immune interactions in depressive disorders and their contribution to psychopathology.

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Crossref · 10.1038/sj.mp.4000572

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37 of 37 references verified0 citation errors · 0 not checkable

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Authors
Dantzer, R., Wollman, E., Vitkovic, L., & Yirmiya, R.
Affiliations
  • Inserm (FR)
  • Centre National de la Recherche Scientifique (FR)
  • Hebrew University of Jerusalem (IL)
Corresponding author
Dantzer, R
Venue
Molecular Psychiatry
Published
1999-07-01
Volume
4
Issue
4
Pages
328-332
ISSN
  • 1359-4184 (ISSN-L)
  • 1476-5578
OpenAlex
W2063650882
Cited by
174
References
37
Citations by year
2026: 1 · 2025: 4 · 2024: 4 · 2023: 2 · 2022: 7 · 2021: 5 · 2020: 6 · 2019: 2 · 2018: 3 · 2017: 4 · 2016: 4 · 2015: 8 · 2014: 4 · 2013: 4 · 2012: 4
FWCI
4.19
Type
journal article
Language
en
Open access
closed
Locations
  • Molecular Psychiatry (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Keywords
cytokines, depression, antidepressants, neuroendocrine-immune interaction, neuroinflammation, psychopathology, cytokine imbalance
MeSH terms
Antidepressive Agents, Brain, Depression, Depressive Disorder, Humans, Cytokines

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