Biological detection by optical oxygen sensing

Molecular Cloning: A Laboratory Manual

Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589

Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging

Fox, M. D., & Raichle, M. E. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2201 · Cited by 6,700

Electrochemical Glucose Biosensors

Wang, J. (2008) · Chemical Reviews · doi:10.1021/cr068123a · Cited by 3,498

The third dimension bridges the gap between cell culture and live tissue

Pampaloni, F., Reynaud, E. G., & Stelzer, E. H. K. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2236 · Cited by 2,817

The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting

Maeda, H. (2001) · Advances in Enzyme Regulation · doi:10.1016/s0065-2571(00)00013-3 · Cited by 2,495

Assessing mitochondrial dysfunction in cells

Brand, M. D., & Nicholls, D. G. (2011) · Biochemical Journal · doi:10.1042/bj20110162 · Cited by 2,405

Fluorescence Lifetime Measurements and Biological Imaging

Berezin, M. Y., & Achilefu, S. (2010) · Chemical Reviews · doi:10.1021/cr900343z · Cited by 2,403

THE DETERMINATION OF GASES IN BLOOD AND OTHER SOLUTIONS BY VACUUM EXTRACTION AND MANOMETRIC MEASUREMENT. I

Van Slyke, D. D., & Neill, J. M. (1924) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)85145-6 · Cited by 2,018

Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

Miller, J. S., Stevens, K. R., Yang, M. T., Baker, B. M., Nguyen, D.-H. T., Cohen, D. M., Toro, E., Chen, A. A., Galie, P. A., Yu, X., et al. (2012) · Nature Materials · doi:10.1038/nmat3357 · Cited by 1,917

Fiber-Optic Chemical Sensors and Biosensors

Wolfbeis, O. S. (2006) · Analytical Chemistry · doi:10.1021/ac060490z · Cited by 1,627

Biochemistry of oxidative stress

Halliwell, B. (2007) · Biochemical Society Transactions · doi:10.1042/bst0351147 · Cited by 1,543

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

Carreau, A., Hafny‐Rahbi, B. E., Matejuk, A., Grillon, C., & Kieda, C. (2011) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2011.01258.x · Cited by 1,246

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

Mehta, G., Hsiao, A. Y., Ingram, M., Luker, G. D., & Takayama, S. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.04.045 · Cited by 1,172

Tracing the stepwise oxygenation of the Proterozoic ocean

Scott, C., Lyons, T. W., Bekker, A., Shen, Y., Poulton, S. W., Chu, X., & Anbar, A. D. (2008) · Nature · doi:10.1038/nature06811 · Cited by 1,098

Optical Chemical Sensors

McDonagh, C., Burke, C. S., & MacCraith, B. D. (2008) · Chemical Reviews · doi:10.1021/cr068102g · Cited by 1,026

Optical Biosensors

Borisov, S. M., & Wolfbeis, O. S. (2008) · Chemical Reviews · doi:10.1021/cr068105t · Cited by 1,018

The role of oxygen availability in embryonic development and stem cell function

Simon, M. C., & Keith, B. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2354 · Cited by 967

Cortical functional architecture and local coupling between neuronal activity and the microcirculation revealed by in vivo high-resolution optical imaging of intrinsic signals.

Frostig, R. D., Lieke, E. E., Ts'o, D. Y., & Grinvald, A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.16.6082 · Cited by 959

Die Bestimmung des im Wasser gelösten Sauerstoffes

Winkler, L. W. (1888) · Berichte der deutschen chemischen Gesellschaft · doi:10.1002/cber.188802102122 · Cited by 891

Continuous Recording of Blood Oxygen Tensions by Polarography

Clark, L. C., Wolf, R., Granger, D., & Taylor, Z. (1953) · Journal of Applied Physiology · doi:10.1152/jappl.1953.6.3.189 · Cited by 886

Fiber-Optic Chemical Sensors and Biosensors (2015–2019)

Wang, X.-D., & Wolfbeis, O. S. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.9b04708 · Cited by 833

The oceanic fixed nitrogen and nitrous oxide budgets: Moving targets as we enter the anthropocene?

Codispoti, L. A., Brandes, J. A., Christensen, J. P., Devol, A. H., Naqvi, S. W. A., Paerl, H. W., & Yoshinari, T. (2001) · Scientia Marina · doi:10.3989/scimar.2001.65s285 · Cited by 806

Microbial life under extreme energy limitation

Hoehler, T. M., & Jørgensen, B. B. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro2939 · Cited by 793

Oxygen in acute and chronic wound healing: Oxygen in wound healing

Schreml, S., Szeimies, R. M., Prantl, L., Karrer, S., Landthaler, M., & Babilas, P. (2010) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2010.09804.x · Cited by 792

The Solubility of Oxygen and Ozone in Liquids

Battino, R., Rettich, T. R., & Tominaga, T. (1983) · Journal of Physical and Chemical Reference Data · doi:10.1063/1.555680 · Cited by 738

Redistribution of Intracellular Oxygen in Hypoxia by Nitric Oxide: Effect on HIF1α

Hagen, T., Taylor, C. T., Lam, F., & Moncada, S. (2003) · Science · doi:10.1126/science.1088805 · Cited by 704

Photophysics and photochemistry of oxygen sensors based on luminescent transition-metal complexes

Carraway, E. R., Demas, J. N., DeGraff, B. A., & Bacon, J. R. (1991) · Analytical Chemistry · doi:10.1021/ac00004a007 · Cited by 638

5-Aminolevulinic Acid-Based Photodynamic Therapy: Principles and Experimental Research

Peng, Q., Berg, K., Moan, J., Kongshaug, M., & Nesland, J. M. (1997) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1997.tb08549.x · Cited by 615

Tissue oxygen tension and brain sensitivity to hypoxia

Erecińska, M., & Silver, I. A. (2001) · Respiration Physiology · doi:10.1016/s0034-5687(01)00306-1 · Cited by 615

Making sense of low oxygen sensing

Bailey-Serres, J., Fukao, T., Gibbs, D. J., Holdsworth, M. J., Lee, S. C., Licausi, F., Perata, P., Voesenek, L. A. C. J., & van Dongen, J. T. (2012) · Trends in Plant Science · doi:10.1016/j.tplants.2011.12.004 · Cited by 609

An optical method for measurement of dioxygen concentration based upon quenching of phosphorescence.

Vanderkooi, J. M., Maniara, G., Green, T. J., & Wilson, D. F. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)45596-2 · Cited by 592

Fiber-Optic Chemical Sensors and Biosensors

Wolfbeis, O. S. (2008) · Analytical Chemistry · doi:10.1021/ac800473b · Cited by 571

Oxidative stress in cell culture: an under‐appreciated problem?

Halliwell, B. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)00235-7 · Cited by 534

Imaging of phosphorescence: a novel method for measuring oxygen distribution in perfused tissue

Rumsey, W., Vanderkooi, J., & Wilson, D. (1988) · Science · doi:10.1126/science.241.4873.1649 · Cited by 534

Molecular Imaging of Hypoxia

Krohn, K. A., Link, J. M., & Mason, R. P. (2008) · Journal of Nuclear Medicine · doi:10.2967/jnumed.107.045914 · Cited by 506

The Roles of Cerebral Blood Flow, Capillary Transit Time Heterogeneity, and Oxygen Tension in Brain Oxygenation and Metabolism

Jespersen, S. N., & Østergaard, L. (2012) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2011.153 · Cited by 504

The Controlled Display of Biomolecules on Nanoparticles: A Challenge Suited to Bioorthogonal Chemistry

Algar, W. R., Prasuhn, D. E., Stewart, M. H., Jennings, T. L., Blanco-Canosa, J. B., Dawson, P. E., & Medintz, I. L. (2011) · Bioconjugate Chemistry · doi:10.1021/bc200065z · Cited by 502

Optical methods for sensing glucose

Steiner, M.-S., Duerkop, A., & Wolfbeis, O. S. (2011) · Chemical Society Reviews · doi:10.1039/c1cs15063d · Cited by 497

The crucial role of plant mitochondria in orchestrating drought tolerance

Atkin, O. K., & Macherel, D. (2009) · Annals of Botany · doi:10.1093/aob/mcn094 · Cited by 489

High Throughput Microplate Respiratory Measurements Using Minimal Quantities Of Isolated Mitochondria

Rogers, G. W., Brand, M. D., Petrosyan, S., Ashok, D., Elorza, A. A., Ferrick, D. A., & Murphy, A. N. (2011) · PLoS ONE · doi:10.1371/journal.pone.0021746 · Cited by 478

Advances in measuring cellular bioenergetics using extracellular flux

Ferrick, D. A., Neilson, A., & Beeson, C. (2008) · Drug Discovery Today · doi:10.1016/j.drudis.2007.12.008 · Cited by 460

Indicators for optical oxygen sensors

Quaranta, M., Borisov, S. M., & Klimant, I. (2012) · Bioanalytical Reviews · doi:10.1007/s12566-012-0032-y · Cited by 452

Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue

Sakadžić, S., Roussakis, E., Yaseen, M. A., Mandeville, E. T., Srinivasan, V. J., Arai, K., Ruvinskaya, S., Devor, A., Lo, E. H., Vinogradov, S. A., et al. (2010) · Nature Methods · doi:10.1038/nmeth.1490 · Cited by 451

Probes and Polymers for Optical Sensing of Oxygen

Amao, Y. (2003) · Microchimica Acta · doi:10.1007/s00604-003-0037-x · Cited by 444

Rules of Engagement: Interspecies Interactions that Regulate Microbial Communities

Little, A. E. F., Robinson, C. J., Peterson, S. B., Raffa, K. F., & Handelsman, J. (2008) · Annual Review of Microbiology · doi:10.1146/annurev.micro.030608.101423 · Cited by 407

Novel BOD (biological oxygen demand) sensor using mediator-less microbial fuel cell

Kim, B. H., Chang, I. S., Cheol Gil, G., Park, H. S., & Kim, H. J. (2003) · Biotechnology Letters · doi:10.1023/a:1022891231369 · Cited by 394

Hypoxia-Sensitive Fluorescent Probes for in Vivo Real-Time Fluorescence Imaging of Acute Ischemia

Kiyose, K., Hanaoka, K., Oushiki, D., Nakamura, T., Kajimura, M., Suematsu, M., Nishimatsu, H., Yamane, T., Terai, T., Hirata, Y., et al. (2010) · Journal of the American Chemical Society · doi:10.1021/ja105937q · Cited by 373

Oxygen quenching of pyrenebutyric acid fluorescence in water. Dynamic probe of the microenvironment

Vaughn, W., & Weber, G. (1970) · Biochemistry · doi:10.1021/bi00805a003 · Cited by 365

Oxygen indicators and intelligent inks for packaging food

Mills, A. (2005) · Chemical Society Reviews · doi:10.1039/b503997p · Cited by 364

Phosphorescent Light–Emitting Iridium Complexes Serve as a Hypoxia-Sensing Probe for Tumor Imaging in Living Animals

Zhang, S., Hosaka, M., Yoshihara, T., Negishi, K., Iida, Y., Tobita, S., & Takeuchi, T. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-3948 · Cited by 349

Pimonidazole: A Novel Hypoxia Marker for Complementary Study of Tumor Hypoxia and Cell Proliferation in Cervical Carcinoma

Varia, M. A., Calkins-Adams, D. P., Rinker, L. H., Kennedy, A. S., Novotny, D. B., Fowler, W. C., & Raleigh, J. A. (1998) · Gynecologic Oncology · doi:10.1006/gyno.1998.5163 · Cited by 342

Multiple fluorescent chemical sensing and imaging

Stich, M. I. J., Fischer, L. H., & Wolfbeis, O. S. (2010) · Chemical Society Reviews · doi:10.1039/b909635n · Cited by 341

A Real-Time Ratiometric Method for the Determination of Molecular Oxygen Inside Living Cells Using Sol−Gel-Based Spherical Optical Nanosensors with Applications to Rat C6 Glioma

Xu, H., Aylott, J. W., Kopelman, R., Miller, T. J., & Philbert, M. A. (2001) · Analytical Chemistry · doi:10.1021/ac0102718 · Cited by 331

Real-Time Measurements of Dissolved Oxygen Inside Live Cells by Organically Modified Silicate Fluorescent Nanosensors

Koo, Y.-E. L., Cao, Y., Kopelman, R., Koo, S. M., Brasuel, M., & Philbert, M. A. (2004) · Analytical Chemistry · doi:10.1021/ac035493f · Cited by 316

Quantitative Microplate-Based Respirometry with Correction for Oxygen Diffusion

Gerencser, A. A., Neilson, A., Choi, S. W., Edman, U., Yadava, N., Oh, R. J., Ferrick, D. A., Nicholls, D. G., & Brand, M. D. (2009) · Analytical Chemistry · doi:10.1021/ac900881z · Cited by 310

Oxygen homeostasis

Semenza, G. L. (2010) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.69 · Cited by 297

Spontaneous cancer and its possible relationship to oxygen metabolism.

Totter, J. R. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.4.1763 · Cited by 296

Oxyphor R2 and G2: phosphors for measuring oxygen by oxygen-dependent quenching of phosphorescence

Dunphy, I., Vinogradov, S. A., & Wilson, D. F. (2002) · Analytical Biochemistry · doi:10.1016/s0003-2697(02)00384-6 · Cited by 288

Regulation of Respiration and Fermentation to Control the Plant Internal Oxygen Concentration

Zabalza, A., van Dongen, J. T., Froehlich, A., Oliver, S. N., Faix, B., Gupta, K. J., Schmälzlin, E., Igal, M., Orcaray, L., Royuela, M., et al. (2009) · Plant Physiology · doi:10.1104/pp.108.129288 · Cited by 287

Advances in Light Microscopy for Neuroscience

Wilt, B. A., Burns, L. D., Wei Ho, E. T., Ghosh, K. K., Mukamel, E. A., & Schnitzer, M. J. (2009) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.051508.135540 · Cited by 278

The evolution of glycogen and starch metabolism in eukaryotes gives molecular clues to understand the establishment of plastid endosymbiosis

Ball, S., Colleoni, C., Cenci, U., Raj, J. N., & Tirtiaux, C. (2011) · Journal of Experimental Botany · doi:10.1093/jxb/erq411 · Cited by 277

Phosphorescent Oxygen Sensor with Dendritic Protection and Two-Photon Absorbing Antenna

Briñas, R. P., Troxler, T., Hochstrasser, R. M., & Vinogradov, S. A. (2005) · Journal of the American Chemical Society · doi:10.1021/ja052947c · Cited by 267

Live-Cell Super-Resolution Imaging with Synthetic Fluorophores

van de Linde, S., Heilemann, M., & Sauer, M. (2012) · Annual Review of Physical Chemistry · doi:10.1146/annurev-physchem-032811-112012 · Cited by 266

Pulse oximetry: its invention, theory, and future

Aoyagi, T. (2003) · Journal of Anesthesia · doi:10.1007/s00540-003-0192-6 · Cited by 263

An error analysis of the rapid lifetime determination method for the evaluation of single exponential decays

Ballew, R. M., & Demas, J. N. (1989) · Analytical Chemistry · doi:10.1021/ac00176a007 · Cited by 262

Simultaneous two-photon imaging of oxygen and blood flow in deep cerebral vessels

Lecoq, J., Parpaleix, A., Roussakis, E., Ducros, M., Houssen, Y. G., Vinogradov, S. A., & Charpak, S. (2011) · Nature Medicine · doi:10.1038/nm.2394 · Cited by 258

ALA and its clinical impact, from bench to bedside

Krammer, B., & Plaetzer, K. (2008) · Photochemical & Photobiological Sciences · doi:10.1039/b712847a · Cited by 251

Two New “Protected” Oxyphors for Biological Oximetry: Properties and Application in Tumor Imaging

Esipova, T. V., Karagodov, A., Miller, J., Wilson, D. F., Busch, T. M., & Vinogradov, S. A. (2011) · Analytical Chemistry · doi:10.1021/ac2022234 · Cited by 247

Calibration of Oxygen-Dependent Quenching of the Phosphorescence of Pd-meso-tetra (4-Carboxyphenyl) Porphine: A Phosphor with General Application for Measuring Oxygen Concentration in Biological Systems

Lo, L.-W., Koch, C. J., & Wilson, D. F. (1996) · Analytical Biochemistry · doi:10.1006/abio.1996.0144 · Cited by 240

PHOTOLUMINESCENCE OF SINGLET OXYGEN IN PIGMENT SOLUTIONS

Krasnovsky, A. A. (1979) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1979.tb09255.x · Cited by 240

Shallow breathing: bacterial life at low O2

Morris, R. L., & Schmidt, T. M. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro2970 · Cited by 240

Oxygen Microscopy by Two‐Photon‐Excited Phosphorescence

Finikova, O. S., Lebedev, A. Y., Aprelev, A., Troxler, T., Gao, F., Garnacho, C., Muro, S., Hochstrasser, R. M., & Vinogradov, S. A. (2008) · ChemPhysChem · doi:10.1002/cphc.200800296 · Cited by 240

Dual Fluorescence Sensor for Trace Oxygen and Temperature with Unmatched Range and Sensitivity

Baleizão, C., Nagl, S., Schäferling, M., Berberan-Santos, M. N., & Wolfbeis, O. S. (2008) · Analytical Chemistry · doi:10.1021/ac801034p · Cited by 236

Ratiometric optical oxygen sensing: a review in respect of material design

Feng, Y., Cheng, J., Zhou, L., Zhou, X., & Xiang, H. (2012) · The Analyst · doi:10.1039/c2an35907c · Cited by 233

Dendritic Phosphorescent Probes for Oxygen Imaging in Biological Systems

Lebedev, A. Y., Cheprakov, A. V., Sakadžić, S., Boas, D. A., Wilson, D. F., & Vinogradov, S. A. (2009) · ACS Applied Materials & Interfaces · doi:10.1021/am9001698 · Cited by 231

Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture

Mehta, G., Mehta, K., Sud, D., Song, J. W., Bersano-Begey, T., Futai, N., Heo, Y. S., Mycek, M.-A., Linderman, J. J., & Takayama, S. (2007) · Biomedical Microdevices · doi:10.1007/s10544-006-9005-7 · Cited by 231

Optical probes and techniques for O2 measurement in live cells and tissue

Dmitriev, R. I., & Papkovsky, D. B. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0914-0 · Cited by 230

Microvascular and tissue oxygen gradients in the rat mesentery

Tsai, A. G., Friesenecker, B., Mazzoni, M. C., Kerger, H., Buerk, D. G., Johnson, P. C., & Intaglietta, M. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.12.6590 · Cited by 230

A New Prodrug-Derived Ratiometric Fluorescent Probe for Hypoxia: High Selectivity of Nitroreductase and Imaging in Tumor Cell

Cui, L., Zhong, Y., Zhu, W., Xu, Y., Du, Q., Wang, X., Qian, X., & Xiao, Y. (2011) · Organic Letters · doi:10.1021/ol102975t · Cited by 227

Ratiometric Molecular Sensor for Monitoring Oxygen Levels in Living Cells

Yoshihara, T., Yamaguchi, Y., Hosaka, M., Takeuchi, T., & Tobita, S. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201107557 · Cited by 222

LOCAL BRAIN HAEMODYNAMICS AND OXYGEN METABOLISM IN CEREBROVASCULAR DISEASE: POSITRON EMISSION TOMOGRAPHY

SETTE, G., BARON, J. C., MAZOYER, B., LEVASSEUR, M., PAPPATA, S., & CROUZEL, C. (1989) · Brain · doi:10.1093/brain/112.4.931 · Cited by 219

Oxygen and the Spatial Structure of Microbial Communities

Fenchel, T., & Finlay, B. (2008) · Biological Reviews · doi:10.1111/j.1469-185x.2008.00054.x · Cited by 216

Molecular Fluorescence, Phosphorescence, and Chemiluminescence Spectrometry

Das, S., Powe, A. M., Baker, G. A., Valle, B., El-Zahab, B., Sintim, H. O., Lowry, M., Fakayode, S. O., McCarroll, M. E., Patonay, G., et al. (2012) · Analytical Chemistry · doi:10.1021/ac202904n · Cited by 213

Oxygen diffusion in biological and artificial membranes determined by the fluorochrome pyrene.

Fischkoff, S., & Vanderkooi, J. M. (1975) · The Journal of general physiology · doi:10.1085/jgp.65.5.663 · Cited by 211

Oxymetry deep in tissues with low-frequency electron paramagnetic resonance.

Halpern, H. J., Yu, C., Peric, M., Barth, E., Grdina, D. J., & Teicher, B. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.26.13047 · Cited by 195

PGC-1α is coupled to HIF-1α-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells

O'Hagan, K. A., Cocchiglia, S., Zhdanov, A. V., Tambuwala, M. M., Cummins, E. P., Monfared, M., Agbor, T. A., Garvey, J. F., Papkovsky, D. B., Taylor, C. T., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808801106 · Cited by 193

Aerobic Microbial Respiration in 86-Million-Year-Old Deep-Sea Red Clay

Røy, H., Kallmeyer, J., Adhikari, R. R., Pockalny, R., Jørgensen, B. B., & D’Hondt, S. (2012) · Science · doi:10.1126/science.1219424 · Cited by 192

Nanoparticle PEBBLE Sensors in Live Cells and In Vivo

Koo Lee, Y.-E., Smith, R., & Kopelman, R. (2009) · Annual Review of Analytical Chemistry · doi:10.1146/annurev.anchem.1.031207.112823 · Cited by 189

Intracellular O2 Sensing Probe Based on Cell-Penetrating Phosphorescent Nanoparticles

Fercher, A., Borisov, S. M., Zhdanov, A. V., Klimant, I., & Papkovsky, D. B. (2011) · ACS Nano · doi:10.1021/nn200807g · Cited by 187

Optical and pharmacological tools to investigate the role of mitochondria during oxidative stress and neurodegeneration

Foster, K. A., Galeffi, F., Gerich, F. J., Turner, D. A., & Müller, M. (2006) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2006.07.001 · Cited by 187

Generation of oxygen gradients in microfluidic devices for cell culture using spatially confined chemical reactions

Chen, Y.-A., King, A. D., Shih, H.-C., Peng, C.-C., Wu, C.-Y., Liao, W.-H., & Tung, Y.-C. (2011) · Lab on a Chip · doi:10.1039/c1lc20325h · Cited by 185

“Overshoot” of O2Is Required to Maintain Baseline Tissue Oxygenation at Locations Distal to Blood Vessels

Devor, A., Sakadžić, S., Saisan, P. A., Yaseen, M. A., Roussakis, E., Srinivasan, V. J., Vinogradov, S. A., Rosen, B. R., Buxton, R. B., Dale, A. M., et al. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.1968-11.2011 · Cited by 183

Emerging Applications of Phosphorescent Metalloporphyrins

Papkovsky, D. B., & O’Riordan, T. C. (2005) · Journal of Fluorescence · doi:10.1007/s10895-005-2830-x · Cited by 181

Prediction of Liver Injury Induced by Chemicals in Human With a Multiparametric Assay on Isolated Mouse Liver Mitochondria

Porceddu, M., Buron, N., Roussel, C., Labbe, G., Fromenty, B., & Borgne-Sanchez, A. (2012) · Toxicological Sciences · doi:10.1093/toxsci/kfs197 · Cited by 181

Metabolic Profiling of Hypoxic Cells Revealed a Catabolic Signature Required for Cell Survival

Frezza, C., Zheng, L., Tennant, D. A., Papkovsky, D. B., Hedley, B. A., Kalna, G., Watson, D. G., & Gottlieb, E. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024411 · Cited by 177

The Pervasive Presence of Fluctuating Oxygenation in Tumors

Cárdenas-Navia, L. I., Mace, D., Richardson, R. A., Wilson, D. F., Shan, S., & Dewhirst, M. W. (2008) · Cancer Research · doi:10.1158/0008-5472.can-07-6387 · Cited by 176

Analysis of mitochondrial function using phosphorescent oxygen-sensitive probes

Will, Y., Hynes, J., Ogurtsov, V. I., & Papkovsky, D. B. (2006) · Nature Protocols · doi:10.1038/nprot.2006.351 · Cited by 171

Optical Oxygen Sensors for Applications in Microfluidic Cell Culture

Grist, S. M., Chrostowski, L., & Cheung, K. C. (2010) · Sensors · doi:10.3390/s101009286 · Cited by 169

Mitochondrial PO2 measured by delayed fluorescence of endogenous protoporphyrin IX

Mik, E. G., Stap, J., Sinaasappel, M., Beek, J. F., Aten, J. A., van Leeuwen, T. G., & Ince, C. (2006) · Nature Methods · doi:10.1038/nmeth940 · Cited by 168

State‐of‐the‐art in downstream processing of monoclonal antibodies: Process trends in design and validation

Marichal‐Gallardo, P., & Álvarez, M. M. (2012) · Biotechnology Progress · doi:10.1002/btpr.1567 · Cited by 166

Methods for Assessing Mitochondrial Function in Diabetes

Perry, C. G. R., Kane, D. A., Lanza, I. R., & Neufer, P. D. (2013) · Diabetes · doi:10.2337/db12-1219 · Cited by 166

G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization

Papkovskaia, T. D., Chau, K.-Y., Inesta-Vaquera, F., Papkovsky, D. B., Healy, D. G., Nishio, K., Staddon, J., Duchen, M. R., Hardy, J., Schapira, A. H. V., et al. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds244 · Cited by 163

Characterization of Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes: Bioenergetics and Utilization in Safety Screening

Rana, P., Anson, B., Engle, S., & Will, Y. (2012) · Toxicological Sciences · doi:10.1093/toxsci/kfs233 · Cited by 161

Photoactivation turns green fluorescent protein red

Elowitz, M. B., Surette, M. G., Wolf, P.-E., Stock, J., & Leibler, S. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00342-3 · Cited by 161

Frontiers in Optical Imaging of Cerebral Blood Flow and Metabolism

Devor, A., Sakadžić, S., Srinivasan, V. J., Yaseen, M. A., Nizar, K., Saisan, P. A., Tian, P., Dale, A. M., Vinogradov, S. A., Franceschini, M. A., et al. (2012) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2011.195 · Cited by 160

Multispectral fluorescence lifetime imaging by TCSPC

Becker, W., Bergmann, A., & Biskup, C. (2007) · Microscopy Research and Technique · doi:10.1002/jemt.20432 · Cited by 159

A Phosphorescent Nanoparticle‐Based Probe for Sensing and Imaging of (Intra)Cellular Oxygen in Multiple Detection Modalities

Kondrashina, A. V., Dmitriev, R. I., Borisov, S. M., Klimant, I., O'Brien, I., Nolan, Y. M., Zhdanov, A. V., & Papkovsky, D. B. (2012) · Advanced Functional Materials · doi:10.1002/adfm.201201387 · Cited by 158

A novel microfluidic platform for high-resolution imaging of a three-dimensional cell culture under a controlled hypoxic environment

Funamoto, K., Zervantonakis, I. K., Liu, Y., Ochs, C. J., Kim, C., & Kamm, R. D. (2012) · Lab on a Chip · doi:10.1039/c2lc40306d · Cited by 153

Mitochondrial respiration protects against oxygen-associated DNA damage

Sung, H. J., Ma, W., Wang, P., Hynes, J., O’Riordan, T. C., Combs, C. A., McCoy, J. P., Bunz, F., Kang, J., & Hwang, P. M. (2010) · Nature Communications · doi:10.1038/ncomms1003 · Cited by 149

Investigation of Drug-Induced Mitochondrial Toxicity Using Fluorescence-Based Oxygen-Sensitive Probes

Hynes, J., Marroquin, L. D., Ogurtsov, V. I., Christiansen, K. N., Stevens, G. J., Papkovsky, D. B., & Will, Y. (2006) · Toxicological Sciences · doi:10.1093/toxsci/kfj208 · Cited by 149

Quantification of live and dead probiotic bacteria in lyophilised product by real-time PCR and by flow cytometry

Kramer, M., Obermajer, N., Matijašić, B. B., Rogelj, I., & Kmetec, V. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-009-2068-7 · Cited by 148

Rapid-response Atmospheric Oxygen Monitor based on Fluorescence Quenching

Bergman, I. (1968) · Nature · doi:10.1038/218396a0 · Cited by 142

In Vivo Mitochondrial Oxygen Tension Measured by a Delayed Fluorescence Lifetime Technique

Mik, E. G., Johannes, T., Zuurbier, C. J., Heinen, A., Houben-Weerts, J. H. P. M., Balestra, G. M., Stap, J., Beek, J. F., & İnce, C. (2008) · Biophysical Journal · doi:10.1529/biophysj.107.126094 · Cited by 139

Techniques for oxygen transfer measurement in bioreactors: a review

Suresh, S., Srivastava, V. C., & Mishra, I. (2009) · Journal of Chemical Technology & Biotechnology · doi:10.1002/jctb.2154 · Cited by 139

Interaction of dioxygen with the electronic excited state of Ir(III) and Ru(II) complexes: Principles and biomedical applications

Ruggi, A., van Leeuwen, F. W. B., & Velders, A. H. (2011) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2011.05.012 · Cited by 137

Review: Quantifying Mitochondrial Dysfunction in Complex Diseases of Aging

Horan, M. P., Pichaud, N., & Ballard, J. W. O. (2012) · The Journals of Gerontology Series A · doi:10.1093/gerona/glr263 · Cited by 137

Targeted Luminescent Near-Infrared Polymer-Nanoprobes for In Vivo Imaging of Tumor Hypoxia

Napp, J., Behnke, T., Fischer, L. H., Würth, C., Wottawa, M., Katschinski, D. M., Alves, F., Resch‐Genger, U., & Schäferling, M. (2011) · Analytical Chemistry · doi:10.1021/ac201870b · Cited by 134

Reversible Off–On Fluorescence Probe for Hypoxia and Imaging of Hypoxia–Normoxia Cycles in Live Cells

Takahashi, S., Piao, W., Matsumura, Y., Komatsu, T., Ueno, T., Terai, T., Kamachi, T., Kohno, M., Nagano, T., & Hanaoka, K. (2012) · Journal of the American Chemical Society · doi:10.1021/ja310049d · Cited by 133

Imaging local neuronal activity by monitoring PO2 transients in capillaries

Parpaleix, A., Houssen, Y. G., & Charpak, S. (2013) · Nature Medicine · doi:10.1038/nm.3059 · Cited by 131

Optical biosensors : today and tomorrow

Ligler, F. S., & Taitt, C. R. (2008) · doi:10.1016/b978-0-444-53125-4.x5001-3 · Cited by 128

Microfluidic dissolved oxygen gradient generator biochip as a useful tool in bacterial biofilm studies

Skolimowski, M., Nielsen, M. W., Emnéus, J., Molin, S., Taboryski, R., Sternberg, C., Dufva, M., & Geschke, O. (2010) · Lab on a Chip · doi:10.1039/c003558k · Cited by 128

Tolerance of dormant and active cells in Pseudomonas aeruginosa PA01 biofilm to antimicrobial agents

Kim, J., Hahn, J., Franklin, M. J., Stewart, P. S., & Yoon, J. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn462 · Cited by 125

Oxygen advection and diffusion in a three-dimensional vascular anatomical network

Fang, Q., Sakadžić, S., Ruvinskaya, L., Devor, A., Dale, A. M., & Boas, D. A. (2008) · Optics Express · doi:10.1364/oe.16.017530 · Cited by 122

Tonic signaling from O2 sensors sets neural circuit activity and behavioral state

Busch, K. E., Laurent, P., Soltész, Z., Murphy, R. J., Faivre, O., Hedwig, B., Thomas, M. V., Smith, H., & de Bono, M. (2012) · Nature Neuroscience · doi:10.1038/nn.3061 · Cited by 120

Overexpression of Pyruvate Dehydrogenase Kinase 1 and Lactate Dehydrogenase A in Nerve Cells Confers Resistance to Amyloid β and Other Toxins by Decreasing Mitochondrial Respiration and Reactive Oxygen Species Production

Newington, J. T., Rappon, T., Albers, S. S., Wong, D. Y. L., Rylett, R. J., & Cumming, R. C. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.366195 · Cited by 118

Real-time determination of intracellular oxygen in bacteria using a genetically encoded FRET-based biosensor

Potzkei, J., Kunze, M., Drepper, T., Gensch, T., Jaeger, K., & Büchs, J. (2012) · BMC Biology · doi:10.1186/1741-7007-10-28 · Cited by 115

Mimicking dynamic in vivo environments with stimuli-responsive materials for cell culture

Kim, J., & Hayward, R. C. (2012) · Trends in biotechnology · doi:10.1016/j.tibtech.2012.04.003 · Cited by 114

Hypoxia in the regulation of neural stem cells

Filippis, L. D., & Delia, D. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0723-5 · Cited by 111

New and Fast Method To Quantify Respiration Rates of Bacterial and Plankton Communities in Freshwater Ecosystems by Using Optical Oxygen Sensor Spots

Warkentin, M., Freese, H. M., Karsten, U., & Schumann, R. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00405-07 · Cited by 111

A Multicompartment Vascular Model for Inferring Baseline and Functional Changes in Cerebral Oxygen Metabolism and Arterial Dilation

Huppert, T. J., Allen, M., Benav, H., Jones, P., & Boas, D. A. (2007) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600435 · Cited by 111

Multiplex bacterial growth monitoring in 24‐well microplates using a dual optical sensor for dissolved oxygen and pH

Kocincová, A. S., Nagl, S., Arain, S., Krause, C., Borisov, S. M., Arnold, M., & Wolfbeis, O. S. (2008) · Biotechnology and Bioengineering · doi:10.1002/bit.21793 · Cited by 110

Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism

O′Flaherty, L., Adam, J., Heather, L. C., Zhdanov, A. V., Chung, Y., Miranda, M. X., Croft, J., Olpin, S. E., Clarke, K. J., Pugh, C. W., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq305 · Cited by 110

Tunable Fluorescent/Phosphorescent Platinum(II) Porphyrin–Fluorene Copolymers for Ratiometric Dual Emissive Oxygen Sensing

Xiang, H., Zhou, L., Feng, Y., et al. (2012) · Inorganic Chemistry · doi:10.1021/ic300040n · Cited by 107

Generation of oxygen gradients with arbitrary shapes in a microfluidic device

Adler, M., Polinkovsky, M. E., Gutierrez, E., & Groisman, A. (2009) · Lab on a Chip · doi:10.1039/b920401f · Cited by 106

An Optical Multifrequency Phase-Modulation Method Using Microbeads for Measuring Intracellular Oxygen Concentrations in Plants

Schmälzlin, E., van Dongen, J. T., Klimant, I., Marmodée, B., Steup, M., Fisahn, J., Geigenberger, P., & Löhmannsröben, H. (2005) · Biophysical Journal · doi:10.1529/biophysj.105.063453 · Cited by 106

Photosystems and global effects of oxygenic photosynthesis

Nelson, N. (2010) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2010.10.011 · Cited by 105

Culturing Aerobic and Anaerobic Bacteria and Mammalian Cells with a Microfluidic Differential Oxygenator

Lam, R. H. W., Kim, M., & Thorsen, T. (2009) · Analytical Chemistry · doi:10.1021/ac9006864 · Cited by 104

Near Infrared Luminescent Oxygen Nanosensors with Nanoparticle Matrix Tailored Sensitivity

Lee, Y.-E. K., Ulbrich, E. E., Kim, G., Hah, H. J., Strollo, C. M., Fan, W., Gurjar, R. S., Koo, S., & Kopelman, R. (2010) · Analytical Chemistry · doi:10.1021/ac1015358 · Cited by 101

Computational evaluation of oxygen and shear stress distributions in 3D perfusion culture systems: Macro-scale and micro-structured models

Cioffi, M., Küffer, J., Ströbel, S., Dubini, G., Martín, I., & Wendt, D. J. (2008) · Journal of Biomechanics · doi:10.1016/j.jbiomech.2008.07.023 · Cited by 100

Methods in Optical Oxygen Sensing: Protocols and Critical Analyses

Papkovsky, D. B. (2004) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(04)81046-2 · Cited by 97

Oxygen gradients in the microcirculation

Pittman, R. N. (2011) · Acta Physiologica · doi:10.1111/j.1748-1716.2010.02232.x · Cited by 97

Microfluidic oxygen imaging using integrated optical sensor layers and a color camera

Ungerböck, B., Charwat, V., Ertl, P., & Mayr, T. (2013) · Lab on a Chip · doi:10.1039/c3lc41315b · Cited by 96

Renal oxidative stress, oxygenation, and hypertension

Palm, F., & Nordquist, L. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00720.2010 · Cited by 96

In Situ Calibration of Optode-Based Oxygen Sensors

Uchida, H., Kawano, T., Kaneko, I., & Fukasawa, M. (2008) · Journal of Atmospheric and Oceanic Technology · doi:10.1175/2008jtecho549.1 · Cited by 95

Decreased Expression of Cytosolic Pyruvate Kinase in Potato Tubers Leads to a Decline in Pyruvate Resulting in an in Vivo Repression of the Alternative Oxidase

Oliver, S. N., Lunn, J. E., Urbańczyk-Wochniak, E., Lytovchenko, A., van Dongen, J. T., Faix, B., Schmälzlin, E., Fernie, A. R., & Geigenberger, P. (2008) · PLANT PHYSIOLOGY · doi:10.1104/pp.108.126516 · Cited by 94

Dendritic upconverting nanoparticles enable in vivo multiphoton microscopy with low-power continuous wave sources

Esipova, T. V., Ye, X., Collins, J. E., Sakadžić, S., Mandeville, E. T., Murray, C. B., & Vinogradov, S. A. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1213291110 · Cited by 93

Differential regulation of HIF ‐mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts

Morten, K., Badder, L. M., & Knowles, H. J. (2013) · The Journal of Pathology · doi:10.1002/path.4159 · Cited by 92

Analysis of Intracellular Oxygen and Metabolic Responses of Mammalian Cells by Time-Resolved Fluorometry

O’Riordan, T. C., Zhdanov, A. V., Ponomarev, G. V., & Papkovsky, D. B. (2007) · Analytical Chemistry · doi:10.1021/ac701770b · Cited by 92

Assessment of drug-induced mitochondrial dysfunction via altered cellular respiration and acidification measured in a 96-well platform

Nadanaciva, S., Rana, P., Beeson, G. C., Chen, D., Ferrick, D. A., Beeson, C., & Will, Y. (2012) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-012-9446-z · Cited by 91

Marine Chemical Technology and Sensors for Marine Waters: Potentials and Limits

Moore, T. S., Mullaugh, K. M., Holyoke, R. R., Madison, A. S., Yücel, M., & Luther, G. W. (2008) · Annual Review of Marine Science · doi:10.1146/annurev.marine.010908.163817 · Cited by 89

Mitochondrial pyrimidine nucleotide carrier (PNC1) regulates mitochondrial biogenesis and the invasive phenotype of cancer cells

Favre, C., Zhdanov, A. V., Leahy, M., Papkovsky, D. B., & O’Connor, R. (2010) · Oncogene · doi:10.1038/onc.2010.146 · Cited by 85

Synthetic approaches for the conjugation of porphyrins and related macrocycles to peptides and proteins

Giuntini, F., Alonso, C. M. A., & Boyle, R. W. (2011) · Photochemical & Photobiological Sciences · doi:10.1039/c0pp00366b · Cited by 82

Ratiometric luminescent molecular oxygen sensors based on uni-luminophores of C⁁N Pt(ii)(acac) complexes that show intense visible-light absorption and balanced fluorescence/phosphorescence dual emission

Liu, Y., Guo, H., & Zhao, J. (2011) · Chemical Communications · doi:10.1039/c1cc14582g · Cited by 81

Modulating Temporal and Spatial Oxygenation over Adherent Cellular Cultures

Oppegard, S. C., Nam, K., Carr, J. R., Skaalure, S. C., & Eddington, D. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006891 · Cited by 79

Assessment of Cellular Oxygen Gradients with a Panel of Phosphorescent Oxygen-Sensitive Probes

Dmitriev, R. I., Zhdanov, A. V., Jasionek, G., & Papkovsky, D. B. (2012) · Analytical Chemistry · doi:10.1021/ac3000144 · Cited by 79

In Vivo Phosphorescence Imaging of pO2 Using Planar Oxygen Sensors

Babilas, P., Liebsch, G., Schacht, V., Klimant, I., Wolfbeis, O. S., Szeimies, R., & Abels, C. (2005) · Microcirculation · doi:10.1080/10739680591003314 · Cited by 78

Ruthenium Complexes with Hydrophobic Ligands That Are Key Factors for the Optical Imaging of Physiological Hypoxia

Komatsu, H., Yoshihara, K., Yamada, H., Kimura, Y., Son, A., Nishimoto, S., & Tanabe, K. (2012) · Chemistry - A European Journal · doi:10.1002/chem.201202809 · Cited by 78

The bioenergetic role of dioxygen and the terminal oxidase(s) in cyanobacteria

Paumann, M., Regelsberger, G., Obinger, C., & Peschek, G. A. (2005) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2004.12.007 · Cited by 77

Are physiological oxygen concentrations mutagenic?

Bruyninckx, W. J., Mason, H. S., & Morse, S. A. (1978) · Nature · doi:10.1038/274606a0 · Cited by 77

A high-throughput dual parameter assay for assessing drug-induced mitochondrial dysfunction provides additional predictivity over two established mitochondrial toxicity assays

Hynes, J., Nadanaciva, S., Swiss, R. L., Carey, C., Kirwan, S., & Will, Y. (2012) · Toxicology in Vitro · doi:10.1016/j.tiv.2012.11.002 · Cited by 74

Competition between oxygen and nitrate respirations in continuous culture of Pseudomonas aeruginosa performing aerobic denitrification

Chen, F., Xia, Q., & Ju, L. (2006) · Biotechnology and Bioengineering · doi:10.1002/bit.20812 · Cited by 74

Regulating Oxygen Levels in a Microfluidic Device

Thomas, P. C., Raghavan, S. R., & Forry, S. P. (2011) · Analytical Chemistry · doi:10.1021/ac202300g · Cited by 74

Fluorescent microparticles for sensing cell microenvironment oxygen levels within 3D scaffolds

Acosta, M. A., Ymele‐Leki, P., Kostov, Y. V., & Leach, J. B. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.02.021 · Cited by 73

Mitochondrial oxygen tension within the heart

Mik, E. G., İnce, C., Eerbeek, O., Heinen, A., Stap, J., Hooibrink, B., Schumacher, C. A., Balestra, G. M., Johannes, T., Beek, J. F., et al. (2009) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2009.02.002 · Cited by 72

Phosphorescence quenching method for measurement of intracellular P O 2 in isolated skeletal muscle fibers

Hogan, M. C. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.86.2.720 · Cited by 71

Binding of misonidazole to hypoxic cells in monolayer and spheroid culture: Evidence that a side-chain label is bound as efficiently as a ring label

Raleigh, J. A., Franko, A. J., Koch, C. J., & Born, J. L. (1985) · British Journal of Cancer · doi:10.1038/bjc.1985.33 · Cited by 70

Tomographic imaging of oxygen by phosphorescence lifetime

Apreleva, S. V., Wilson, D. F., & Vinogradov, S. A. (2006) · Applied Optics · doi:10.1364/ao.45.008547 · Cited by 70

Oxygen, pH, and mitochondrial oxidative phosphorylation

Wilson, D. F., Harrison, D. K., & Vinogradov, S. A. (2012) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01160.2012 · Cited by 68

Design and development of microbioreactors for long-term cell culture in controlled oxygen microenvironments

Abaci, H. E., Devendra, R., Smith, Q., Gerecht, S., & Drazer, G. (2012) · Biomedical Microdevices · doi:10.1007/s10544-011-9592-9 · Cited by 67

New Insights in Drug-Induced Mitochondrial Toxicity

Nadanaciva, S., & Will, Y. (2011) · Current Pharmaceutical Design · doi:10.2174/138161211796904795 · Cited by 67

A sensitive bacterial luminescence probe for O2 in biochemical systems

Oshino, R., Oshino, N., Tamura, M., et al. (1972) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(72)90185-7 · Cited by 66

Quantifying the role of oxygen pressure in tissue function

Wilson, D. F. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01293.2007 · Cited by 65

Intracellular oxygen-sensitive phosphorescent probes based on cell-penetrating peptides

Dmitriev, R. I., Zhdanov, A. V., Ponomarev, G. V., Yashunski, D., & Papkovsky, D. B. (2009) · Analytical Biochemistry · doi:10.1016/j.ab.2009.10.048 · Cited by 65

2D luminescence imaging of physiological wound oxygenation

Schreml, S., Meier, R. J., Wolfbeis, O. S., Maisch, T., Szeimies, R., Landthaler, M., Regensburger, J., Santarelli, F., Klimant, I., & Babilas, P. (2011) · Experimental Dermatology · doi:10.1111/j.1600-0625.2011.01263.x · Cited by 63

Monitoring of cell oxygenation and responses to metabolic stimulation by intracellular oxygen sensing technique

Zhdanov, A. V., Ogurtsov, V. I., Taylor, C. T., & Papkovsky, D. B. (2010) · Integrative Biology · doi:10.1039/c0ib00021c · Cited by 63

P o 2measurements in the microcirculation using phosphorescence quenching microscopy at high magnification

Golub, A. S., & Pittman, R. N. (2008) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01347.2007 · Cited by 60

Investigation of Mitochondrial Dysfunction by Sequential Microplate-Based Respiration Measurements from Intact and Permeabilized Neurons

Clerc, P., & Polster, B. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034465 · Cited by 59

In vitro analysis of cell metabolism using a long-decay pH-sensitive lanthanide probe and extracellular acidification assay

Hynes, J., O’Riordan, T. C., Zhdanov, A. V., Uray, G., Will, Y., & Papkovsky, D. B. (2009) · Analytical Biochemistry · doi:10.1016/j.ab.2009.04.016 · Cited by 58

Phosphorescent nanoparticles for quantitative measurements of oxygen profiles in vitro and in vivo

Choi, N., Verbridge, S. S., Williams, R. M., Chen, J., Kim, J., Schmehl, R. H., Farnum, C. E., Zipfel, W. R., Fischbach, C., & Stroock, A. D. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2011.11.048 · Cited by 57

Design of metalloporphyrin-based dendritic nanoprobes for two-photon microscopy of oxygen

Lebedev, A. Y., Troxler, T., & Vinogradov, S. A. (2008) · Journal of Porphyrins and Phthalocyanines · doi:10.1142/s1088424608000649 · Cited by 57

Luminescent dual sensor for time-resolved imaging of pCO2 and pO2 in aquatic systems

Schroeder, C. R., Neurauter, G., & Klimant, I. (2007) · Microchimica Acta · doi:10.1007/s00604-006-0696-5 · Cited by 56

Light-Induced Retinal Vascular Damage by Pd-porphyrin Luminescent Oxygen Probes

Stepinac, T., Chamot, S. R., Rungger‐Brändle, E., Ferrez, P. W., Munoz, J.-L., van den Bergh, H., Riva, C. E., Pournaras, C. J., & Wagnières, G. (2005) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.04-0500 · Cited by 55

Cell-Penetrating Conjugates of Coproporphyrins with Oligoarginine Peptides: Rational Design and Application for Sensing Intracellular O2

Dmitriev, R. I., Ropiak, H. M., Ponomarev, G. V., Yashunsky, D. V., & Papkovsky, D. B. (2011) · Bioconjugate Chemistry · doi:10.1021/bc200324q · Cited by 55

Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondria

Zhdanov, A. V., Dmitriev, R. I., & Papkovsky, D. B. (2010) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0502-8 · Cited by 54

Miniaturized fiber-optic hybrid sensor for continuous glucose monitoring in subcutaneous tissue

Pasic, A., Koehler, H., Klimant, I., & Schaupp, L. A. (2006) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2006.05.010 · Cited by 53

Oxygen dependence of respiration in rat spinotrapezius muscle in situ

Golub, A. S., & Pittman, R. N. (2012) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00131.2012 · Cited by 53

Genome-wide investigation of cellular targets and mode of action of the antifungal bacterial metabolite 2,4-diacetylphloroglucinol in Saccharomyces cerevisiae

Troppens, D. M., Dmitriev, R. I., Papkovsky, D. B., O’Gara, F., & Morrissey, J. P. (2013) · FEMS Yeast Research · doi:10.1111/1567-1364.12037 · Cited by 52

Cell uptake and cytotoxicity of a novel cyclometalated iridium(III) complex and its octaarginine peptide conjugate

Dolan, C., Moriarty, R. D., Lestini, E., Devocelle, M. C., Forster, R. J., & Keyes, T. E. (2012) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2012.11.001 · Cited by 51

Oxygen‐dependent delayed fluorescence measured in skin after topical application of 5‐aminolevulinic acid

Harms, F. A., de Boon, W. M. I., Balestra, G. M., Bodmer, S. I. A., Johannes, T., Stolker, R. J., & Mik, E. G. (2011) · Journal of Biophotonics · doi:10.1002/jbio.201100040 · Cited by 50

Transcutaneous pO2 imaging during tourniquet‐induced forearm ischemia using planar optical oxygen sensors

Babilas, P., Lamby, P. E., Prantl, L., Schreml, S., Jung, E. M., Liebsch, G., Wolfbeis, O. S., Landthaler, M., Szeimies, R., & Abels, C. (2008) · Skin Research and Technology · doi:10.1111/j.1600-0846.2008.00295.x · Cited by 50

Influence of matrices on oxygen sensing of three sensing films with chemically conjugated platinum porphyrin probes and preliminary application for monitoring of oxygen consumption of Escherichia coli (E. coli)

Tian, Y., Shumway, B. R., Gao, W., Youngbull, C., Holl, M. R., Johnson, R. H., & Meldrum, D. R. (2010) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2010.08.036 · Cited by 50

Oxygen optodes as fast sensors for eddy correlation measurements in aquatic systems

Chipman, L., Huettel, M., Berg, P., Meyer, V., Klimant, I., Glud, R. N., & Wenzhöfer, F. (2012) · Limnology and Oceanography Methods · doi:10.4319/lom.2012.10.304 · Cited by 50

A Truncated Progesterone Receptor (PR-M) Localizes to the Mitochondrion and Controls Cellular Respiration

Dai, Q., Shah, A. A., Garde, R. V., Yonish, B. A., Zhang, L., Medvitz, N. A., Miller, S., Hansen, E. L., Dunn, C. N., & Price, T. M. (2013) · Molecular Endocrinology · doi:10.1210/me.2012-1292 · Cited by 49

Muscle intracellular oxygenation during exercise: optimization for oxygen transport, metabolism, and adaptive change

Wagner, P. D. (2011) · European Journal of Applied Physiology · doi:10.1007/s00421-011-1955-7 · Cited by 49

Chorioretinal Vascular Oxygen Tension Changes in Response to Light Flicker

Shakoor, A., Blair, N. P., Mori, M. T., et al. (2006) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.06-0291 · Cited by 48

Real-time, in vivo measurement of tissular pO2 through the delayed fluorescence of endogenous protoporphyrin IX during photodynamic therapy

Piffaretti, F. M., Novello, A. M., Kumar, R. S., Forte, E., Paulou, C., Nowak-Sliwinska, P. M., van den Bergh, H., & Wagnières, G. (2012) · Journal of Biomedical Optics · doi:10.1117/1.jbo.17.11.115007 · Cited by 47

P o 2 profiles near arterioles and tissue oxygen consumption in rat mesentery

Golub, A. S., Barker, M. C., & Pittman, R. N. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00077.2007 · Cited by 47

Photoacoustic probing of fluorophore excited state lifetime with application to oxygen sensing

Ashkenazi, S., Huang, S.-W., Horvath, T. D., Koo, Y.-E. L., & Kopelman, R. (2008) · Journal of Biomedical Optics · doi:10.1117/1.2927466 · Cited by 46

New ratiometric optical oxygen and pH dual sensors with three emission colors for measuring photosynthetic activity in cyanobacteria

Lü, H., Jin, Y., Tian, Y., Zhang, W., Holl, M. R., & Meldrum, D. R. (2011) · Journal of Materials Chemistry · doi:10.1039/c1jm13754a · Cited by 46

A system of miniaturized stirred bioreactors for parallel continuous cultivation of yeast with online measurement of dissolved oxygen and off‐gas

Klein, T., Schneider, K. P., & Heinzle, E. (2012) · Biotechnology and Bioengineering · doi:10.1002/bit.24633 · Cited by 45

Optical methods for sensing and imaging oxygen: materials, spectroscopies and applications

Wang, X.-D., & Wolfbeis, O. S. (2014) · Chem. Soc. Rev. · doi:10.1039/c4cs00039k · Cited by 1,114

Limitations of Oxygen Delivery to Cells in Culture: An Underappreciated Problem in Basic and Translational Research

Place, T. L., Domann, F. E., & Case, A. J. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.10.003 · Cited by 434

Recent advances in intelligent food packaging materials: Principles, preparation and applications

Cheng, H., Xu, H., Julian McClements, D., Chen, L., Jiao, A., Tian, Y., Miao, M., & Jin, Z. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2021.131738 · Cited by 367

Frequently asked questions in hypoxia research

Wenger, R., Kurtcuoglu, V., Scholz, C., Marti, H., & Hoogewijs, D. (2015) · Hypoxia · doi:10.2147/hp.s92198 · Cited by 223