Nonalcoholic Fatty Liver Disease

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

Esterbauer, H., Schaur, R. J., & Zollner, H. (1991) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(91)90192-6 · Cited by 6,672

Steatohepatitis: A tale of two “hits”?

Day, C. P., & James, O. F. W. (1998) · Gastroenterology · doi:10.1016/s0016-5085(98)70599-2 · Cited by 4,285

Nonalcoholic Steatohepatitis: A Proposal for Grading and Staging The Histological Lesions

Brunt, E. M., Janney, C. G., Di Bisceglie, A. M., Neuschwander-Tetri, B. A., & Bacon, B. R. (1999) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.01377.x · Cited by 3,907

Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity.

MATTEONI, C., YOUNOSSI, Z., GRAMLICH, T., BOPARAI, N., LIU, Y., & MCCULLOUGH, A. (1999) · Gastroenterology · doi:10.1016/s0016-5085(99)70506-8 · Cited by 3,345

Overweight and obesity in the United States: prevalence and trends, 1960–1994

Flegal, K., Carroll, M., Kuczmarski, R., & Johnson, C. (1998) · International Journal of Obesity · doi:10.1038/sj.ijo.0800541 · Cited by 3,045

The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994

Alter, M. J., Kruszon‐Moran, D., Nainan, O. V., McQuillan, G. M., Gao, F., Moyer, L. A., Kaslow, R. A., & Margolis, H. S. (1999) · New England Journal of Medicine · doi:10.1056/nejm199908193410802 · Cited by 2,973

Nonalcoholic Steatohepatitis

Ludwig, J., Viggiano, T. R., McGill, D. B., & Ott, B. J. (1980) · Mayo Clinic Proceedings · doi:10.1016/s0025-6196(24)00530-5 · Cited by 2,903

Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988–1994

Harris, M. I., Flegal, K. M., Cowie, C. C., Eberhardt, M. S., Goldstein, D. E., Little, R. R., Wiedmeyer, H.-M., & Byrd-Holt, D. D. (1998) · Diabetes Care · doi:10.2337/diacare.21.4.518 · Cited by 2,703

IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance

Hotamisligil, G. S., Peraldi, P., Budavari, A., Ellis, R., White, M. F., & Spiegelman, B. M. (1996) · Science · doi:10.1126/science.271.5249.665 · Cited by 2,630

Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities

Sanyal, A. J., Campbell–Sargent, C., Mirshahi, F., Rizzo, W. B., Contos, M. J., Sterling, R. K., Luketic, V. A., Shiffman, M. L., & Clore, J. N. (2001) · Gastroenterology · doi:10.1053/gast.2001.23256 · Cited by 2,078

Non‐alcoholic fatty liver disease comorbid with major depressive disorder: the pathological features and poor therapeutic efficacy

Tomeno, W., Kawashima, K., Yoneda, M., Saito, S., Ogawa, Y., Honda, Y., Kessoku, T., Imajo, K., Mawatari, H., Fujita, K., et al. (2015) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.12897 · Cited by 98

Improvement of Nonalcoholic Fatty Liver Disease After Bariatric Surgery in Morbidly Obese Chinese Patients

Tai, C.-M., Huang, C.-K., Hwang, J.-C., Chiang, H., Chang, C.-Y., Lee, C.-T., Yu, M.-L., & Lin, J.-T. (2012) · Obesity Surgery · doi:10.1007/s11695-011-0579-7 · Cited by 91

Statins and sepsis.

Gao, F., Linhartova, L., Johnston, A. M., & Thickett, D. R. (2008) · British Journal of Anaesthesia · doi:10.1093/bja/aem406 · Cited by 83

Transgenic mice expressing nuclear sterol regulatory element–binding protein 1c in adipose tissue exhibit liver histology similar to nonalcoholic steatohepatitis

Nakayama, H., Otabe, S., Ueno, T., Hirota, N., Yuan, X., Fukutani, T., Hashinaga, T., Wada, N., & Yamada, K. (2007) · Metabolism · doi:10.1016/j.metabol.2006.11.004 · Cited by 79

Weight loss and weight regain in usual clinical practice: results from the TARGET-NASH observational cohort

Malespin, M. H., Barritt, A. S., Watkins, S. E., Schoen, C., Tincopa, M. A., Corbin, K. D., Mospan, A. R., Munoz, B., Trinh, H. N., Weiss, L. M., et al. (2022) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2021.01.023 · Cited by 75

Probiotic yogurt in the elderly with intestinal bacterial overgrowth: endotoxaemia and innate immune functions

Schiffrin, E. J., Parlesak, A., Bode, C., Christian Bode, J., van't Hof, M. A., Grathwohl, D., & Guigoz, Y. (2008) · British Journal of Nutrition · doi:10.1017/s0007114508055591 · Cited by 74

Glucagon-Like Peptide-1 Receptor Agonist Prevented the Progression of Hepatocellular Carcinoma in a Mouse Model of Nonalcoholic Steatohepatitis

Kojima, M., Takahashi, H., Kuwashiro, T., Tanaka, K., Mori, H., Ozaki, I., Kitajima, Y., Matsuda, Y., Ashida, K., Eguchi, Y., et al. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165722 · Cited by 69

Association between anxiety and depression and nonalcoholic fatty liver disease

Choi, J. M., Chung, G. E., Kang, S. J., Kwak, M.-S., Yang, J. I., Park, B., & Yim, J. Y. (2021) · Frontiers in Medicine · doi:10.3389/fmed.2020.585618 · Cited by 68

Mitochondrial Reactive Oxygen Species Signal Hepatocyte Steatosis by Regulating the Phosphatidylinositol 3-Kinase Cell Survival Pathway

Kohli, R., Pan, X., Malladi, P., Wainwright, M. S., & Whitington, P. F. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m701759200 · Cited by 67

Quantitative ATP synthesis in human liver measured by localized 31P spectroscopy using the magnetization transfer experiment

Schmid, A. I., Chmelík, M., Szendroedi, J., Krššák, M., Brehm, A., Moser, E., & Roden, M. (2008) · NMR in Biomedicine · doi:10.1002/nbm.1207 · Cited by 67

Glycer-AGEs-RAGE signaling enhances the angiogenic potential of hepatocellular carcinoma by upregulating VEGF expression

Takino, J. (2012) · World Journal of Gastroenterology · doi:10.3748/wjg.v18.i15.1781 · Cited by 64

Leptin in hepatocellular carcinoma

Wang, S.-N. (2010) · World Journal of Gastroenterology · doi:10.3748/wjg.v16.i46.5801 · Cited by 59

Randomized clinical trial: benefits of aerobic physical activity for 24 weeks in postmenopausal women with nonalcoholic fatty liver disease

Rezende, R. E. F., Duarte, S. M. B., Stefano, J. T., Roschel, H., Gualano, B., de Sá Pinto, A. L., Vezozzo, D. C. P., Carrilho, F. J., & Oliveira, C. P. (2016) · Menopause · doi:10.1097/gme.0000000000000647 · Cited by 62

B Cell-Activating Factor is Associated With the Histological Severity of Nonalcoholic Fatty Liver Disease

Miyake, T., Abe, M., Tokumoto, Y., Hirooka, M., Furukawa, S., Kumagi, T., Hamada, M., Kawasaki, K., Tada, F., Ueda, T., et al. (2013) · Hepatology International · doi:10.1007/s12072-012-9345-8 · Cited by 59

Population drinking and liver cirrhosis mortality: is there a link in eastern Europe?

Ramstedt, M. (2007) · Addiction · doi:10.1111/j.1360-0443.2007.01872.x · Cited by 51

Laparoscopic Sleeve Gastrectomy Resolves NAFLD: Another Formal Indication for Bariatric Surgery?

Esquivel, C. M., Garcia, M., Armando, L., Ortiz, G., Lascano, F. M., & Foscarini, J. M. (2018) · Obesity Surgery · doi:10.1007/s11695-018-3466-7 · Cited by 51

SGLT2 inhibitor treatment outcome in nonalcoholic fatty liver disease complicated with diabetes mellitus: the long-term effects on clinical features and liver histopathology

Akuta, N., Kawamura, Y., Fujiyama, S., Sezaki, H., Hosaka, T., Kobayashi, M., Kobayashi, M., Saitoh, S., Suzuki, F., Suzuki, Y., et al. (2020) · Internal Medicine · doi:10.2169/internalmedicine.4398-19 · Cited by 48

Cortisol clearance and associations with insulin sensitivity, body fat and fatty liver in middle-aged men

Holt, H. B., Wild, S. H., Postle, A. D., Zhang, J., Koster, G., Umpleby, M., Shojaee-Moradie, F., Dewbury, K., Wood, P. J., Phillips, D. I., et al. (2007) · Diabetologia · doi:10.1007/s00125-007-0629-9 · Cited by 48

Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr mice by targeting the TGFβ-Smad3 pathway

Lytle, K. A., Depner, C. M., Wong, C. P., & Jump, D. B. (2015) · Journal of Lipid Research · doi:10.1194/jlr.m061275 · Cited by 45

Effect of intragastric balloons on liver enzymes: A systematic review and meta-analysis

Popov, V. B., Thompson, C. C., Kumar, N., Ciarleglio, M. M., Deng, Y., & Laine, L. (2016) · Digestive Diseases and Sciences · doi:10.1007/s10620-016-4178-2 · Cited by 43

Anti-Inflammatory Effects of Spirulina platensis Extract via the Modulation of Histone Deacetylases

Pham, T., Park, Y.-K., & Lee, J.-Y. (2016) · Nutrients · doi:10.3390/nu8060381 · Cited by 44

Bariatric surgery before, during, and after liver transplantation: a systematic review and meta-analysis

Lee, Y., Tian, C., Lovrics, O., Soon, M. S., Doumouras, A. G., Anvari, M., & Hong, D. (2020) · Surgery for Obesity and Related Diseases · doi:10.1016/j.soard.2020.05.012 · Cited by 44

Activation of liver X receptors attenuates endotoxin-induced liver injury in mice with nonalcoholic fatty liver disease

Liu, Y., Han, X., Bian, Z., Peng, Y., You, Z., Wang, Q., Chen, X., Qiu, D., & Ma, X. (2012) · Digestive Diseases and Sciences · doi:10.1007/s10620-011-1902-9 · Cited by 35

Variation of liver SUV on 18FDG-PET/CT studies in women with breast cancer

Groheux, D., Delord, M., Rubello, D., Colletti, P. M., Nguyen, M.-L., & Hindié, E. (2013) · Clinical Nuclear Medicine · doi:10.1097/rlu.0b013e3182872f0e · Cited by 35

Circulating adiponectin levels in type 2 diabetes mellitus patients with or without non-alcoholic fatty liver disease: Results of a small, open-label, randomized controlled intervention trial in a subgroup receiving short-term exenatide

Savvidou, S., Karatzidou, K., Tsakiri, K., Gagalis, A., Hytiroglou, P., & Goulis, J. (2016) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2015.12.003 · Cited by 30

FDG PET/CT of the non-malignant liver in an increasingly obese world population

Keramida, G., & Peters, A. M. (2020) · Clinical Physiology and Functional Imaging · doi:10.1111/cpf.12651 · Cited by 25

Serum immunoglobulin A concentration is a reliable biomarker for liver fibrosis in non-alcoholic fatty liver disease

Maleki, I. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i35.12566 · Cited by 22

Relationship between retinal vascular caliber and coronary artery disease in patients with non-alcoholic fatty liver disease (NAFLD)

Josef, P., Ali, I., Ariel, P., Alon, M., & Nimer, A. (2013) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph10083409 · Cited by 22

Intervention by picroside II on FFAs induced lipid accumulation and lipotoxicity in HepG2 cells

Dhami-Shah, H., Vaidya, R., Talwadekar, M., Shaw, E., Udipi, S., Kolthur-Seetharam, U., & Vaidya, A. D. B. (2021) · Journal of Ayurveda and Integrative Medicine · doi:10.1016/j.jaim.2021.04.007 · Cited by 15

Management of patients with non-alcoholic steatohepatitis undergoing liver transplantation: considerations for the anesthesiologist

Sharma, S., Stine, J. G., Verbeek, T., & Bezinover, D. (2022) · Journal of Cardiothoracic and Vascular Anesthesia · doi:10.1053/j.jvca.2021.07.020 · Cited by 5

Adipose derived mesenchymal stem cell-seeded regenerated silk fibroin scaffolds reverse liver fibrosis in mice

Li, W., Shi, X., Zhang, D., Hu, J., Zhao, S., Ye, S., Wang, J., Liu, X., Zhang, Q., Wang, Z., et al. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb00275c · Cited by 5

Non‐alcoholic fatty liver disease: Further expression of the metabolic syndrome

Tarantino, G., Saldalamacchia, G., Conca, P., & Arena, A. (2007) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2007.04824.x · Cited by 184

Nonalcoholic fatty liver disease is associated with hyperlipidemia and obesity

Sharabi, Y., & Eldad, A. (2000) · The American Journal of Medicine · doi:10.1016/s0002-9343(00)00434-4 · Cited by 41

Non alcoholic fatty liver disease : original

Coetzee, A., & Ascott-Evans, B. (2015) · South African Journal of Diabetes

Nonobese Nonalcoholic Fatty Liver Disease: An Important Clinical Entity

Zaman, A. (2016) · Journal watch · doi:10.1056/nejm-jw.na42300

Nicht alkoholische Fettleberkrankheit (NAFLK)

Keller, K. (2004) · Monatsschrift Kinderheilkunde · doi:10.1007/s00112-004-0995-z · Cited by 1