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Cited by 526

The DOI matches its Crossref record.

PROCEDURAL LEARNING AND NEOSTYRIAL DYSFUNCTION IN MAN

SAINT-CYR, J. A., TAYLOR, A. E., LANG, A. E·1988·Brain

Abstract

Patients with early stage Parkinson's disease are shown to be selectively impaired in a cognitive task of procedural learning while remaining intact in recall and recognition tests of declarative memory. In contrast, amnestic patients showed the opposite set of deficits, thus demonstrating a double dissociation. Patients with early Huntington's disease were either comparable to the parkinsonian patients or to amnestics. In the advanced Huntington's group, both procedural learning and declarative memory were impaired. It is argued that cognitive procedural learning depends on the establishment of heuristic strategies through the action of a circuit which involves the neostriatum and the prefrontal cortex.

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Metadata

Authors
SAINT-CYR, J. A., TAYLOR, A. E., & LANG, A. E.
Venue
Brain
Published
1988-08-01
Volume
111
Issue
4
Pages
941-960
ISSN
  • 0006-8950 (ISSN-L)
  • 1460-2156
OpenAlex
W2130087379
Cited by
526
References
0
FWCI
7.71
Type
journal article
Language
en
Open access
closed

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