Functional localization of the system for visuospatial attention using positron emission tomography
Abstract
PET was used to image the neural system underlying visuospatial attention. Analysis of data at both the group and individual-subject level provided anatomical resolution superior to that described to date. Six right-handed male subjects were selected from a pilot behavioural study in which behavioural responses and eye movements were recorded. The attention tasks involved covert shifts of attention, where peripheral cues indicated the location of subsequent target stimuli to be discriminated. One attention condition emphasized reflexive aspects of spatial orientation, while the other required controlled shifts of attention. PET activations agreed closely with the cortical regions recently proposed to form the core of a neural network for spatial attention. The two attention tasks evoked largely overlapping patterns of neural activation, supporting the existence of a general neural system for visuospatial attention with regional functional specialization. Specifically, neocortical activations were observed in the right anterior cingulate gyrus (Brodmann area 24), in the intraparietal sulcus of right posterior parietal cortex, and in the mesial and lateral premotor cortices (Brodmann area 6).
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Neuroimaging studies have identified a common fronto-parietal attention/control network.
“Neuroimaging studies using a variety of attention tasks14 have identified a common network, often referred to as the fronto-parietal attention/control network72–74.”
From Paying attention to attention in depression (2019) · cites this paper as [74]
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- Authors
- Nobre, A.
- Affiliations
- University of Oxford (GB)
- Corresponding author
- Nobre, A.
- ORCID
- Nobre, A.
- Venue
- Brain
- Publisher
- Oxford University Press (OUP)
- Published
- 1997-03-01
- Volume
- 120
- Issue
- 3
- Pages
- 515-533
- ISSN
- 0006-8950 (ISSN-L)
- 1460-2156
- OpenAlex
- W2116336109
- Cited by
- 900
- References
- 25
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 6 · 2023: 13 · 2022: 16 · 2021: 14 · 2020: 14 · 2019: 14 · 2018: 14 · 2017: 15 · 2016: 12 · 2015: 26 · 2014: 21 · 2013: 27 · 2012: 19
- FWCI
- 37.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Brain (publishedVersion)
- PubMed (publishedVersion)
- BIROn (Birkbeck, University of London) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Funders
- Wellcome Trust
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Spatial Neglect and Hemispheric Dysfunction
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- visuospatial attention, functional localization, anterior cingulate cortex, posterior parietal cortex, intraparietal sulcus, premotor cortex
- MeSH terms
- Attention, Brain, Brain Mapping, Frontal Lobe, Humans, Functional Laterality, Male, Motor Cortex, Parietal Lobe, Psychomotor Performance, Spatial Behavior, Tomography, Emission-Computed, Vision, Ocular, Prefrontal Cortex
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