The DOI matches its Crossref record; 97 of the 98 references it cites were found in a registry or an index; 6 of the 103 sources its claims cite were checked for support.
Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases
Abstract
Chemical communication does appear to occur among humans, but several examples reported in the literature do not meet the proposed definition for communication by pheromones.
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Claims the paper makes
96 Own interpretation · 35 No full text of the sources · 20 Not checked yet · 17 Sources not found · 15 No basis given · 3 Partly supported · 2 Own result · 1 Supported · 1 Supported so far · 1 Own method · accuracy not yet measured
The cited sources support only part of this claim — read each source’s verdict below.
In the paper
“The increase in serum luteinizing hormone and testosterone when male mice and hamsters are exposed to chemosensory stimuli from females appears to be absolutely dependent on vomeronasal integrity (Coquelin et al., 1984;Pfeiffer and Johnston, 1994).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Introduction
What the sources say
- Partly supportedcites Coquelin et al., 1984 sourceExperimental — accuracy not yet measured
The Results (page not provided) show that removing the vomeronasal organ greatly reduced LH responses to female urine in male mice. But some mice without the organ still responded to urine, and most responded to a freely behaving female, so the paper does not establish absolute dependence for all female stimuli. It reports a testosterone finding from another mouse study but does not study testosterone or hamsters itself. (LLM, conf=0.90)
- Partly supportedcites Pfeiffer and Johnston, 1994 sourceExperimental — accuracy not yet measured
The Discussion reports that vomeronasal removal eliminated androgen surges in hamsters investigating female vaginal secretions, and describes comparable LH findings for mice exposed to female urine. But it also says vomeronasal lesions did not eliminate hamster androgen surges during interactions with females; the claimed absolute dependence is therefore broader than the paper supports. The mouse testosterone surge is described as presumed rather than directly established by the cited mouse finding. (LLM, conf=0.89)
hedgeddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- Partly supported
None of the sources cited for this claim have been checked yet.
In the paper
“These authors showed the structure becoming more simplified later in development.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Description: anatomical, developmental and genetic evidence Structure
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“The existence of a VNO in the human embryo similar to the VNOs of other species is undisputed (Boehm and Gasser, 1993).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Description: anatomical, developmental and genetic evidence Structure
What the sources say
- Not checked — no full text of the sourcecites Boehm and Gasser, 1993 source
boosted- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, several examples reported in the literature do not meet the proposed definition for communication by pheromones: 'chemical substances released by one member of a species as communication with another member, to their mutual benefit'.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Abstract
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
In the paper
“Induction of uterine growth and estrus in female prairie voles normally resulting from exposure to males is also dependent on an intact VNO (Tubbiola and Wysocki, 1997).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Introduction
What the sources say
- Not checked — no full text of the sourcecites Tubbiola and Wysocki, 1997 source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
None of the sources cited for this claim have been checked yet.
In the paper
“It is clear from both reports that the number of such cells is small: ~4 per 100 µm epithelial surface (Takami et al., 1993) or less (Trotier et al., 2000).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Microanatomy
What the sources say
- Not checked — no full text of the sourcecites Takami et al., 1993 source
- Not matchedcites Trotier et al., 2000
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
boostedn = 2- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, the absence of OMP and any reports of putative vomeronasal receptor genes (see below) means that any such cells are quite different from known VSNs in other species.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Microanatomy
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Many of the axons in this region belong to other well-recognized systems of the nasal cavity, the trigeminal, autonomic and nervus terminalis systems.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Connectivity
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Numerous reports of a structure identified as the VNO in the nasal septum in adult humans agree that it is a blind ending diverticulum in the septal mucosa opening via a depression (the VNO pit) into the nasal cavity ~2 cm in from the nostril.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Description: anatomical, developmental and genetic evidence Structure
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
None of the sources cited for this claim have been checked yet.
In the paper
“They report an electrophysiological response to application of small amounts of steroid chemicals confined to the VNO region.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Positive evidence?
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
- It may state two separate claims as one. 69
- Probably not a substantial claim. 63
The cited sources support only part of this claim — read each source’s verdict below.
In the paper
“The epithelium lining the human VNO is unlike that of VNOs in other species and unlike that of olfactory or respiratory epithelium in humans (Moran et al., 1991;Stensaas et al., 1991).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Microanatomy
What the sources say
- Partly supportedcites Moran et al., 1991 sourceExperimental — accuracy not yet measured
The paper’s conclusion describes the human VNO lining as unlike other epithelial linings described in the human body, supporting the comparison with human olfactory and respiratory epithelium. In “The fine structure of the VNO in man,” however, it says some human VNO cells resemble cells in the rat VNO’s nonsensory epithelium. The broader claim that the lining is unlike VNO epithelium in other species is therefore not fully supported. (LLM, conf=0.83)
- Not checked — no full text of the sourcecites Stensaas et al., 1991 source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Partly supported
The cited sources support only part of this claim — read each source’s verdict below.
In the paper
“The human vomeronasal epithelium differs in appearance from both the sensory and non-sensory epithelia in the VNOs of other species and from nasal 'respiratory' epithelium (Moran et al., 1991;Stensaas et al., 1991).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Microanatomy
What the sources say
- Partly supportedcites Moran et al., 1991 sourceExperimental — accuracy not yet measured
In “Does the human VNO contain sensory receptors?” (page unavailable), the paper says human VNO cells are not ultrastructurally identical to sensory neurons described in other mammals. “The fine structure of the human VNO” distinguishes a ciliated cell from those in typical respiratory epithelium. But “The fine structure of the VNO in man” says human VNO cells resemble cells in the nonsensory VNO epithelium of mammals such as rats, so the claimed difference from nonsensory epithelium is not supported. (LLM, conf=0.88)
- Not checked — no full text of the sourcecites Stensaas et al., 1991 source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Partly supported
The sources with a verdict support this claim; the rest weren’t checked yet, have no full text we could read, or their verdicts aren’t rated yet.
In the paper
“The recognition of newborn lambs by ewes also appears to depend on the main olfactory system (Levy et al., 1995), although a vomeronasal contribution has also been reported (Booth and Katz, 2000).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
- Not checked — no full text of the sourcecites Levy et al., 1995 source
- Supportedcites Booth and Katz, 2000 source
The Booth and Katz citation is attached to the reported vomeronasal contribution, not the claim about the main olfactory system. In the Discussion, the authors conclude that the vomeronasal organ helps ewes recognize their newborn lambs during nursing. (LLM, conf=0.94)
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
Every source the paper cites for this claim was checked and supports it.
In the paper
“Reproductive suppression in subordinate females, as may occur in some primate species (Barrett et al., 1993), may also involve a conservation of metabolic effort until more favorable circumstances arise.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
- Supportedcites Barrett et al., 1993 source
The citation follows the example of reproductive suppression in subordinate females of some primate species, not the citing authors’ suggestion about conserving metabolic effort. The paper reports that subordinate female marmosets remain anovulatory while housed with dominant females (opening summary); that supports the cited example. (LLM, conf=0.93)
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
- Supported
None of the sources cited for this claim have been checked yet.
In the paper
“It contains bipolar cells similar to the developing vomeronasal sensory neurons of other species and also generates luteinizing hormone releasing hormone (LHRH)producing cells as in other species (Boehm et al., 1994;Kajer and Fischer Hansen, 1996).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Description: anatomical, developmental and genetic evidence Structure
What the sources say
- Not checked — no full text of the sourcecites Boehm et al., 1994 source
- Not matchedcites Kajer and Fischer Hansen, 1996
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“The latter were unable to find any VNO structure at later stages (19 weeks), although others have shown a simplified but clear VNO continuing to increase in size up to at least 30 weeks (Bohm and Gasser, 1993;Smith et al., 1997).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Description: anatomical, developmental and genetic evidence Structure
What the sources say
- Not matchedcites Bohm and Gasser, 1993
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not checked — no full text of the sourcecites Smith et al., 1997 source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Not matched
None of the sources cited for this claim have been checked yet.
In the paper
“The responsive neurons were in the apical zone of the vomeronasal epithelium where most neurons appear to express members of the V1R class of putative vomeronasal receptor genes.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Putative receptor gene expression
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Axon bundles are reported in the submucosa (Stensaas et al., 1991), but do not appear to arise from axon bundles penetrating the lamina propria in the same way as in vomeronasal epithelia of other species.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Microanatomy
What the sources say
- Not checked — no full text of the sourcecites Stensaas et al., 1991 source
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“They have not been shown to have axons leaving the epithelium nor to make synaptic contact with axons in the epithelium, so if they are chemosensitive they have no obvious way of communication with the brain.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Microanatomy
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: unclear — It is unclear why the paper says it holds.
It may state two separate claims as one.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“There are many elongated cells presenting a microvillar surface to the lumen of the organ but most are not similar to microvillar vomeronasal sensory organs (VSNs) of other species.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Microanatomy
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, its relationship to animal vomeronasal genes is not good evidence for such a function and throws no light on the question of human vomeronasal function.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Putative receptor gene expression
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“The structure is reported at least unilaterally in 90% or more of subjects in some reports or in 50% or fewer in other reports.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Description: anatomical, developmental and genetic evidence Structure
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“The location of this structure is consistent with the location of the VNO in embryos (Trotier et al., 2000) and it has a similar simplified form, with no large blood vessels, cavernous sinuses or supporting cartilage.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Description: anatomical, developmental and genetic evidence Structure
What the sources say
- Not matchedcites Trotier et al., 2000
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Not matched
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“There is also evidence in these reports for a systemic physiological response to this stimulation and although anecdotal evidence suggests no conscious response in awake human subjects, there is evidence for an alteration of mood.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Positive evidence?
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“There is no evidence that this nerve is chemosensory or that the human terminalis nerve carries the axons of VSNs (although the two do run together in most mammals), but it may innervate the vomeronasal epithelium (Witkin and Silverman, 1983;Wirsig and Leonard, 1986).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Connectivity
What the sources say
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Trotier et al. estimate ~92% with some evidence of at least one VNO pit in subjects with no septal surgery examined multiple times, but a substantially lower number after septal surgery (Trotier et al., 2000).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Description: anatomical, developmental and genetic evidence Structure
What the sources say
- Not matchedcites Trotier et al., 2000
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The best candidates for VSNs, those expressing NSE, have not been traced in connectivity with axons and neither have any other cells of the human VNO.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Connectivity
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Their expression in the vomeronasal epithelium is no guarantee: some pheromones are clearly detected by the main olfactory system (see below) and possible non-pheromone functions of the vomeronasal system (as in snakes) have not been investigated.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Putative receptor gene expression
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“There is no trace of this structure in adult humans (Humphrey 1940;Meisami and Bhatnagar, 1998), although it is present in the fetus (Chuah and Zeng, 1987), and it is generally reported missing in rhesus monkeys and other old world primates (Wysocki, 1979;Stephan et al., 1982).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Connectivity
What the sources say
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“These genes are expressed in VSNs and are similar in apparent transmembrane organization to olfactory receptor genes (Buck and Axel, 1991), but differ in much of their DNA sequence.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Putative receptor gene expression
What the sources say
- Not checked — no full text of the sourcecites Buck and Axel, 1991 source
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Axons are observed in the epithelium (Stensaas et al., 1991), but not in continuity or in synaptic contact with epithelial cells.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Microanatomy
What the sources say
- Not checked — no full text of the sourcecites Stensaas et al., 1991 source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“There are axons within the human VNO and Schwann cell-wrapped bundles of axons underlying it (Stensaas et al., 1991;Jahnke and Merker, 2000), so it is somewhat surprising that Trotier et al. did not find S100 expression close to the VNO (Trotier et al., 2000).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Connectivity
What the sources say
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“There is no serious error in methodology that is obvious from the published papers, so they have to be taken seriously.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Positive evidence?
boosted- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“These genes were labeled 'putative pheromone receptor genes', although at the time of their discovery the evidence that they might code for pheromone receptor molecules was tenuous.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Putative receptor gene expression
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“The nervus terminalis (Brookover, 1914;Pearson, 1941) characteristically connects the VNO and the brain in the fetus and clearly persists in human adults (Brookover, 1914).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Connectivity
What the sources say
boostedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“Genes similar to the vomeronasal receptor genes are also present in the human genome.Those found in initial searches through the genome are clearly pseudogenes (Dulac and Axel, 1995;Herrada and Dulac, 1997), i.e. they have defects in their sequence that would prevent transcription and translation of the expected transmembrane protein.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Putative receptor gene expression
What the sources say
boosted- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Trotier et al. recently demonstrated that the endoscopic appearance of the VNO pit can vary, unequivocal on one inspection and invisible on a later inspection, or vice versa (Trotier et al., 2000).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Description: anatomical, developmental and genetic evidence Structure
What the sources say
- Not matchedcites Trotier et al., 2000
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
boosted- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Not matched
In the paper
“In a recent paper Rodriguez et al. reported the discovery of a previously undetected human gene closely related to the V1R family in rodents (Rodriguez et al., 2000).Whether it is expressed in human vomeronasal epithelium was not reported, but it is expressed in the main olfactory epithelium.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Putative receptor gene expression
What the sources say
- Not checked — no full text of the sourcecites Rodriguez et al., 2000 source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Not all human sequences related to vomeronasal receptor genes have been investigated in detail, so this negative evidence should be viewed with some caution.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Putative receptor gene expression
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“Whatever its anthropological merit, this argument is logically circular in the context of an evaluation of VNO function because it starts with the premise that there is no human VNO.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
What the sources say
- Not matchedcites Stoddart, 1991
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The hormonal changes elicited by steroid chemicals in these studies are not evidence for a physiological connection between the VNO region and the brain and provide no evidence for VNO function.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Physiology
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, there is no requirement that vomeronasal chemoreceptors be stimulated only by non-volatile chemicals.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
None of the sources cited for this claim have been checked yet.
In the paper
“The steroids elicited clear EVG responses; the conventional odors did not.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Physiology
boosteddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Furthermore, repeated stimulus delivery over a prolonged period would make low level stimulation of other nasal sensory systems or systemic uptake of stimulus chemicals more likely.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Physiology
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: unclear — It is unclear why the paper says it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The precise location of the recording electrode in EVG recording experiments is not well described, but its effective recording volume is likely to be biased towards the regions close to the opening (VNO pit).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Comparison with the EOG
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: unclear — It is unclear why the paper says it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Sensory input of any kind in humans, unless signaling imminent danger, is often subordinate to experiential and cultural factors.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, as discussed above, any local VNO response must be communicated to the brain before a sensory communication pathway is established.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Physiology
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“The trend towards synchronization arises from either shortening or lengthening of the cycle by secretions produced at different phases of the donor's cycle [but see the comment by Whitten (Whitten, 1999)].”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
What the sources say
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“It would seem surprising if all olfactory/chemosensory communication were lost.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“There are close connections with the amygdala and limbic system (Halpern, 1987;Meredith, 1991), the seat of emotional, hormonal and autonomic control, but there are only indirect connections with the cerebral cortex, generally considered to be the site of consciousness.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
What the sources say
- Not matchedcites Halpern, 1987
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not checked — no full text of the sourcecites Meredith, 1991 source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Not matched
In the paper
“These are substances that elicit sexually dimorphic EVGs and are related to skin chemicals claimed to be human pheromones.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
What the sources say
- Not checked — no full text of the sourcecites Jacob and McClintock, 2000 source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Intra-specific chemical communication, some of which is vomeronasal and some olfactory, is a common feature in land mammals.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Higher primates have highly developed visual systems and reduced olfactory systems, but still use olfactory information.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“They conclude that chemical communication does occur and are willing to call the chemical mediators pheromones in some cases.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
What the sources say
- Not matchedcites Preti and Wysocki, 1999
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
- Not matched
In the paper
“It also assumes that detection of 'pheromones' signaling reproductive state would be a vomeronasal function.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
What the sources say
- Not matchedcites Stoddart, 1991
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
- Not matched
In the paper
“The EVG is reported (again without experimental details) not to be eliminated by topical lidocaine, a local anesthetic, or atropine, an autonomic cholinergic antagonist (Monti-Bloch et al., 1998b).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Potential artifacts
What the sources say
- Not matchedcites Monti-Bloch et al., 1998b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
- Not matched
In the paper
“As a second type of response, Monti Bloch et al. have also reported preliminary evidence that bipolar cells aspirated from the human VNO pit show an electrical responses to some 'vomeropherins' (Monti-Bloch et al., 1998b).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Physiology
What the sources say
- Not matchedcites Monti-Bloch et al., 1998b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
hedgeddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The report that local anesthetics fail to block the EVG indicates that nerve transmission is not involved, which rules out CNS reflexes.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Summary: electrical responses
hedgeddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: unclear — It is unclear why the paper says it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The substances involved are unknown and although the effect does appear to be chemosensory, there is no evidence that it is due to vomeronasal sensory input.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
In the paper
“Other studies (Berliner et al., 1996) used a different type of stimulator which was not described in detail and for which there were no control experiments to determine stimulus spread.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Physiology
What the sources say
- Not checked — no full text of the sourcecites Berliner et al., 1996 source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“These include changes in blood pressure and heart rate, small but significant changes in hormonal levels (Monti-Bloch et al., 1998a) and some changes in mood (Grosser et al., 2000).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Physiology
What the sources say
- Not matchedcites Monti-Bloch et al., 1998a
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not checked — no full text of the sourcecites Grosser et al., 2000 source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Not matched
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“The main olfactory system in general has good connections with cerebral cortex, but also has connections to the amygdala.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, in the cases where main olfactory input is the only important information on pheromones we still have no idea whether information about main olfactory pheromones has access to the cortex or is routed through the amygdala and basal forebrain.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“These experiments have not been published in a fully refereed report.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Physiology
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The subjects generally reported no sensation from direct chemical stimulation of the VNO, even when an EVG was recorded, but they reported an odor sensation when an EOG was elicited.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Physiology
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“Although no anatomical connection has been demon-strated, Monti-Bloch et al. deduce a physiological connection with the brain because stimulus delivery to the VNO pit elicited several systemic responses (Monti-Bloch and Grosser, 1991Grosser, , 1998a,b),b).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Physiology
What the sources say
- Not checked — no full text of the sourcecites Monti-Bloch and Grosser, 1991 source
- Not matchedcites Grosser, 1998a,b
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Preti and Wysocki's conclusions are based on specific examples, but a similar conclusion would not be outrageous on basic principles.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. It may state two separate claims as one.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“Priming pheromones produce a change of state in the receiver, usually a change in hormonal secretion that primes the animal for a later response.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Perhaps we don't need to distinguish categorically between priming and signaling communications: both are essentially informational.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Furthermore, one of the prime examples of main olfactory pheromones, nipple search behavior in rabbits, appears not to be learned, although the same response pattern can be conditioned to arbitrary odors.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Some benefit to the receiver in avoiding parasite transmission may be associated with avoidance of fecal odors, but a similar benefit with respect to general body odors is less likely, and a benefit to the sender in either case seems doubtful if no definite message is transmitted.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“It may well be in both of these cases that the learning involved is imprinting of a particular combination from a limited set of signals.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In this case the chemical is not a pheromone although a response normally elicited by pheromonal communication has been linked to it by conditioning.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plaincorrelationalSingle case- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“There are many biological chemicals that can be expected to evoke behavioral and mood changes.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plainconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Inter-specific communication could be mutually beneficial, for example where chemosensory information about defense chemicals benefits the receiver by allowing avoidance.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Some of these responses, such as avoidance and disgust with fecal and body odors, may be culturally determined.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The essence of the concept is that a particular chemical or complex of chemicals communicates meaning and, thus, must be identified.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. The paper may give no reason why it holds. It may state two separate claims as one.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“The other class of pheromones, releasing pheromones, were originally considered to release a stereotyped behavioral pattern that required no further information for its completion.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Chemical communication occurs in humans.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Worst case: Vomeronasal function is not necessary to explain any aspect of chemical communication in humans, nor is it necessary for pheromonal communication.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper may give no reason why it holds.
None of the sources cited for this claim have been checked yet.
In the paper
“This concept seemed inappropriate for mammals, where responses are often modified by experience or other contingencies, and behavioral responses are now said to be elicited by 'signaling' pheromones (Bronson, 1971(Bronson, , 1976;;Albone, 1984).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
- Not checked — no full text of the sourcecites Bronson, 1971
- Not checked — no full text of the sourcecites Bronson, 1976 source
- Not matchedcites Albone, 1984
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Identifying mutual benefit in a given case is not always easy, but the criterion provides a conceptual framework for understanding the establishment of a chemical communication.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plain- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Too rigid a definition can make its applicability to real situations so limited that it is useless.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Odor communication between flowers and pollinating insects is mutually beneficial, but I would not label it pheromonal because it occurs across species, even though its evolutionary mechanisms may be similar to those maintaining intra-specific mutually beneficial communication.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“The term pheromone was coined to describe a chemical substance which carries a message about the physiological or behavioral state of an insect to members of its own species, resulting in 'a specific reaction, for example a definite behaviour or a developmental process' (Karlson and Luscher, 1959).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
- Not checked — no full text of the sourcecites Karlson and Luscher, 1959 source
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“These are not pheromone communications because they are not mutually beneficial and not intra-specific.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plain- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. The paper may give no reason why it holds. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The existence of a functional VNO in humans would not be ruled out either by the presence or the absence of pheromone communication in humans nor, if present, by any of its features, such as learned versus unlearned responses.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Best case:
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper may give no reason why it holds. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Similarly, too broad a definition devalues the term and also makes it useless.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“It can be argued (Beauchamp et al., 1976) that there is no need for a special term for mutually beneficial chemical communication, but, as emphasized by Karlson and Luscher (Karlson and Luscher, 1959), some distinction between communication and a casual use of chemosensory information does seem a useful distinction.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“We know that in humans mood can affect future behavior (a sign of information transfer) and reliable biases in behavior could have evolutionary consequences.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgeddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Particular chemicals may be associated with particular objects, but there may be no necessity for the chemicals to be identified, and the associations can be reassigned.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. The paper may give no reason why it holds. It may state two separate claims as one.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“On the other hand, a change of mood on exposure to a human-derived chemical (Grosser et al., 2000;Jacob and McClintock, 2000) does not adequately define a pheromone.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
plain- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“There are other sensory systems that could be involved.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Function: evidence from chemical communication?
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
In the paper
“They concluded that there is evidence for priming pheromones in humans, including the data on menstrual cycle shifts (although the latter do not clearly meet the mutual benefit criterion proposed here) (Preti and Wysocki, 1999).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
- Not matchedcites Preti and Wysocki, 1999
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plainconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“This would require that the communication contributed to evolutionary 'fitness' for both sender and receiver.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgeddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
In the paper
“In the presence of male stimuli, group housed females return to estrus cycling (the 'Whitten Effect') (Whitten, 1959), clearly a mutually beneficial response.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
- Not matchedcites Whitten, 1959
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
boosteddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Nevertheless, there seems to be some advantage to our communication in arbitrarily limiting the term pheromone to intra-specific communication.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“It is clear in the original description, and in a later more extensive review of examples (Karlson and Butenandt, 1959), that this was to be real communication, beneficial to the sender and, by implication, to the receiver.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
boosteddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“This mechanism is less suitable for communication where the messages have special meanings.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plain- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“The response of newborn rabbits to the mother's nipple (Hudson and Distel, 1986), referred to above, and the standing response of a receptive female pig to the male's pheromone (Dorries et al., 1997) both depend on the main olfactory system.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
- Not checked — no full text of the sourcecites Hudson and Distel, 1986 source
- Not matchedcites Dorries et al., 1997
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Furthermore, if we concentrate on pheromone communication rather than pheromone chemicals, we avoid definitional problems associated with chemicals that have different meanings in different contexts or to different individuals, for example mature versus immature or male versus female.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“If this mutual benefit requirement is included as an explicit part of the definition (Rutowski, 1981;Meredith, 1983), the application of the term becomes more restricted but more scientifically useful.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Non-specialist functions of mammalian olfactory systems may involve a simple association between a complex of chemicals and an external situation, permitting later recognition of similar situations.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In cases where the subordinate and dominant females are genetically related there might be some increase in inclusive fitness (inclusive fitness takes into account an individual's contribution to the reproductive success of related individuals that carry some of the same genes).”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In this case the mutual benefit is clear, and a good case can be made for many other priming pheromonal communications in mice.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
boosteddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“We can be sure that the authors did not mean that the individual organism created this capacity, but that it was established and maintained by natural selection.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
boosted- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. It may state two separate claims as one.
In the paper
“They did not find solid evidence for signaling pheromones but they point out that mammalian, and especially human, behavior is influenced by many factors.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
What the sources say
- Not matchedcites Preti and Wysocki, 1999
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
- Not matched
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The fact that the same chemicals may be used by different species, whether or not in different combinations or different circumstances, is also not a problem.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plain- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Where a mutual advantage does not seem reasonable, communication is suspect.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“The recognition of a mate's pheromone signature in the pregnancy block or 'Bruce effect' in mice also appears to be learned, but this is a vomeronasal process.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
hedgeddirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: unclear — It is unclear why the paper says it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Many examples of 'a specific reaction' to biological chemicals are then excluded from the category of 'pheromone communications'.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“It does imply that meaning is not infinitely reassignable; that it is not just an association even though there are instances where arbitrary odors can be substituted for preprogrammed stimuli.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“If there is no communication there seems no reason to use a special term.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Pheromones
plain- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“If we didn't have the positive evidence from EVG, autonomic and psychological responses, reasonable scientific judgment would assign the role of detecting human-derived chemicals that might be involved in chemical communication to the main olfactory system.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Opinion:
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The presence or absence of pheromones and pheromonal communication is independent of the existence and/or functionality of a human VNO.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Worst case: Vomeronasal function is not necessary to explain any aspect of chemical communication in humans, nor is it necessary for pheromonal communication.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper may give no reason why it holds. It may state two separate claims as one.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“However, ignoring the evidence for vomeronasal function because most of it comes with commercial baggage is not a rational scientific response in the absence of evidence for error, bias or fraud.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Opinion:
plain- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The EVG constitutes evidence for a selective and sensitive response to human-derived chemicals located in the region of the VNO.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Opinion:
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
- Rests on an assumption: The electrical and systemic responses recorded from the VNO region are not artifacts of electrode movement or leakage of stimuli to the olfactory area.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The expression of a vomeronasal-type receptor gene in humans raises the possibility that such genes may underlie chemosensitivity in the vomeronasal region.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Summary: evidence for human vomeronasal function
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper may give no reason why it holds.
A conclusion the paper draws from its own results — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Systemic autonomic responses and emotional changes elicited by stimulation in this region suggest some chemosensitivity, even though the anatomical substrate is difficult to demonstrate and seems unlikely to be conventional VSNs.”
§ Human Vomeronasal Organ Function: A Critical Review of Best and Worst Cases > Opinion:
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
- Rests on an assumption: The electrical and systemic responses recorded from the VNO region are not artifacts of electrode movement or leakage of stimuli to the olfactory area.
The paper relies on this without support.
Whether vomeronasal systems in mammals have any similar non-social communication functions has not been thoroughly investigated.
“Whether the vomeronasal systems in mammals have any similar non-social communication functions has not been thoroughly investigated.”
The paper relies on this without support.
There has been a long-standing dispute over whether there is a VNO at all in adults.
“In humans there has been a long-standing dispute over whether there is a VNO at all in adults.”
The paper relies on this without support.
The electrical and systemic responses recorded from the VNO region are not artifacts of electrode movement or leakage of stimuli to the olfactory area.
“The local response is an artifact, albeit surprisingly dependent on the nature of the stimulus, perhaps because of electrode movement between stimulations.Alternatively, the response could be from non-chemosensory cells with no connections to the brain.Systemic responses could be due to leakage of stimuli to the olfactory area.”
Citations
Cites
A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
Buck, L., & Axel, R. (1991) · Cell · doi:10.1016/0092-8674(91)90418-x · Cited by 4,987
‘Pheromones’: a New Term for a Class of Biologically Active Substances
KARLSON, P., & LÜSCHER, M. (1959) · Nature · doi:10.1038/183055a0 · Cited by 1,364 · cited 7×
“The term pheromone was coined to describe a chemical substance which carries a message about the physiological or behavioral state of an insect to members of its own species, resulting in 'a specific reaction, for example a definite behaviour or a developmental process' (Karlson and Luscher, 1959).”
BackgroundInfluentialOrigin of luteinizing hormone-releasing hormone neurons
Schwanzel-Fukuda, M., & Pfaff, D. W. (1989) · Nature · doi:10.1038/338161a0 · Cited by 1,116
A novel family of genes encoding putative pheromone receptors in mammals
Dulac, C., & Axel, R. (1995) · Cell · doi:10.1016/0092-8674(95)90161-2 · Cited by 1,001
Menstrual Synchrony and Suppression
MCCLINTOCK, M. K. (1971) · Nature · doi:10.1038/229244a0 · Cited by 777
The Organization and Function of the Vomeronasal System
Halpern, M. (1987) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.10.030187.001545 · Cited by 732
A Multigene Family Encoding a Diverse Array of Putative Pheromone Receptors in Mammals
Matsunami, H., & Buck, L. B. (1997) · Cell · doi:10.1016/s0092-8674(00)80537-1 · Cited by 706
Herrada, G., & Dulac, C. (1997) · Cell · doi:10.1016/s0092-8674(00)80536-x · Cited by 696
Metabolic fuels and reproduction in female mammals
Wade, G. N., & Schneider, J. E. (1992) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80183-6 · Cited by 686
A New Multigene Family of Putative Pheromone Receptors
Ryba, N. J. P., & Tirindelli, R. (1997) · Neuron · doi:10.1016/s0896-6273(00)80946-0 · Cited by 598
Research works printed but not linked: 2
- [22]22. Getchell, T.V. and Getchell, M.L. (1987) Peripheral mechanims of olfaction: biochemistry and neurophysiology. In Finger, T. and Silver, W. (eds), Neurobiology of Taste and Smell. Wiley, New York, pp. 91-123.
- [63]63. Preti, G. and Wysocki, C.J. (1999) Human pheromones: releasers or primers: fact or myth. In Johnston, R.E., Muller-Schwartze, D. and Sorenson, P. (eds), Advances in Chemical Communication in Vertebrates. Plenum Press, New York, pp. 315-331.
Cited by
Sorted by citations
Items 101–200 of 279
Mishor, E., Amir, D., Weiss, T., Honigstein, D. R., Weissbrod, A., Livne, E., Gorodisky, L., Karagach, S., Ravia, A., Snitz, K., et al. (2021) · Science Advances · doi:10.1126/sciadv.abg1530 · Cited by 29
“The notion of pheromonal communication was once considered dependent on a functional vomeronasal system, a system that humans may not have (62).”
BackgroundDarwin's Legacy: An Evolutionary View of Women's Reproductive and Sexual Functioning
Harris, A. L., & Vitzthum, V. J. (2013) · The Journal of Sex Research · doi:10.1080/00224499.2012.763085 · Cited by 30
“Environmental factors, pheromonal signals, and social factors have all been proposed and debated (e.g., McClintock, 1971, 1981; Meredith, 2001; Stern & McClintock, 1998; Trotier et al., 2000; Weller & Weller, 1993).”
BackgroundAre Pheromones Detected Through the Main Olfactory Epithelium?
Wang, Z., Nudelman, A. S., & Storm, D. R. (2007) · Molecular Neurobiology · doi:10.1007/s12035-007-0014-1 · Cited by 27
“Humans, like other vertebrates, do have a VNO; however, the VNO is not functional in adults [11].”
BackgroundChanges in the Odor Quality of Androstadienone During Exposure-Induced Sensitization
Jacob, T. J. C., Wang, L., Jaffer, S., & McPhee, S. (2005) · Chemical Senses · doi:10.1093/chemse/bji073 · Cited by 28
Pheromones and Mammalian Behavior
Brennan, P. (2009) · Frontiers in neuroscience · doi:10.1201/9781420071993-c6 · Cited by 33
Charpentier, M. J. E., Mboumba, S., DITSOGA, C., & Drea, C. M. (2013) · American Journal of Primatology · doi:10.1002/ajp.22146 · Cited by 29
“…baboons, various macaques and one colobine species [Smith et al., 2001a], but there is evidence that adult humans and chimpanzees have retained a VNO‐like structure [Bhatnagar & Smith, 2001; Johnson et al., 1985; Smith et al., 1998, 2001b], the function of which remains unclear [Meredith, 2001].”
BackgroundHecker, N., Lächele, U., Stuckas, H., Giere, P., & Hiller, M. (2019) · Molecular Ecology · doi:10.1111/mec.15180 · Cited by 25
“…about the regression of the VNO in adult humans, the lack of sensory neurons suggests that the human VNO is not functional (D'Aniello et al., 2017; Meredith, 2001) [Colour figure can be viewed at wileyonlinelibrary.com] Homo sapiens Pan troglodytes Pan paniscus Gorilla gorilla gorilla Pongo…”
BackgroundBhatnagar, K. P., Smith, T. D., & Winstead, W. I. (2002) · American Journal of Rhinology · doi:10.1177/194589240201600611 · Cited by 27
Karunadasa, D. K., Chapman, C., & Bicknell, R. J. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.04795.x · Cited by 26
“It may be of interest that the human vomeronasal system is considered by some to be vestigial in most humans (Trotier et al., 2000; Meredith, 2001), and yet evidence exists for pheromonal influences on human physiology (Stern & McClintock, 1998).”
BackgroundMolecular Biology of Peptide Pheromone Production and Reception in Mice
Touhara, K. (2007) · Advances in genetics · doi:10.1016/s0065-2660(07)59006-1 · Cited by 27
Knecht, M., Lundström, J. N., Witt, M., Hüttenbrink, K., Heilmann, S., & Hummel, T. R. (2003) · Behavioral Neuroscience · doi:10.1037/0735-7044.117.6.1135 · Cited by 25
“Cells of the human VNE exhibit little or no immunoreactivity for neuronal markers such as olfactory marker protein or PGP 9.5 (Takami et al., 1993; Witt et al., 2002), which would indicate their olfactory or neuronal activity, respectively (for a discussion on the functionality of the human VNO, see also Meredith, 200…”
BackgroundInfluentialRevisiting the Vomeronasal System From an Integrated Perspective
Salazar, I., Barrios, A. W., & Sánchez‐Quinteiro, P. (2016) · The Anatomical Record · doi:10.1002/ar.23470 · Cited by 25
Belanger, R. M., Corkum, L., & Zielinski, B. (2007) · Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · doi:10.1016/j.cbpa.2006.11.008 · Cited by 24
“Pheromones have been defined as substances, or mixtures of substances, that are released to the outside by individuals into the environment where they induce specific, adaptive and largely innate biological responses in conspecifics that are mutually beneficial to both the sender and receiver (Karlson and Luscher, 195…”
BackgroundThe scented brain: pheromonal responses in humans.
Sobel, N., & Brown, W. M. (2001) · Neuron · doi:10.1016/s0896-6273(01)00406-8 · Cited by 21
“Thus, the question of human VNO functionality remains open (reviewed in Meredith, 2001).”
BackgroundHull, E. M., & Dominguez, J. M. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-397175-3.00049-1 · Cited by 24
The failure to detect drug-induced sensory loss in standard preclinical studies
Gauvin, D. V., Abernathy, M. M., Tapp, R. L., Yoder, J. D., Dalton, J. A., & Baird, T. J. (2015) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/j.vascn.2015.05.011 · Cited by 24
“The selective pressure to retain vomeronasal chemosensory input has been lost in higher primates including humans (Dulac & Torello, 2003; Meredith, 2001).”
BackgroundConscious Sensation, Conscious Perception and Sensorimotor Theories of Consciousness
Gamez, D. (2014) · Studies in applied philosophy, epistemology and rational ethics · doi:10.1007/978-3-319-05107-9_11 · Cited by 23
Neuronal types of the human cortical amygdaloid nucleus
Vásquez, C. E., Reberger, R., Dall’Oglio, A., Calcagnotto, M. E., & Rasia‐Filho, A. A. (2018) · The Journal of Comparative Neurology · doi:10.1002/cne.24527 · Cited by 22
“The inputs that originate in the vomeronasal organ, and thus the designation “vomeronasal amygdala,” occur in the human embryo, but are no longer present in the postnatal brain (Gloor, 1997) or appear just as a remnant in adults (Meredith, 2001).”
BackgroundHuman Pheromone Detection by the Vomeronasal Organ: Unnecessary for Mate Selection?
Mast, T. G., & Samuelsen, C. L. (2009) · Chemical Senses · doi:10.1093/chemse/bjp030 · Cited by 22
“The adult human VNO has been repeatedly reviewed as nonfunctional (Keverne 1999; Meredith 2001; Wysocki and Preti 2004).”
BackgroundComparative study of chemical neuroanatomy of the olfactory neuropil in mouse, honey bee, and human
Sinakevitch, I. G., Bjorklund, G. R., Newbern, J. M., Gerkin, R. C., & Smith, B. H. (2017) · Biological Cybernetics · doi:10.1007/s00422-017-0728-8 · Cited by 22
“No structure strictly analogous to the AOB has been identified in the adult human olfactory system (Bhatnagar et al. 1987); however, its status during development remains controversial (see review by Meredith 2001).”
Accessory chemosignaling mechanisms in primates
Evans, C. S. (2006) · American Journal of Primatology · doi:10.1002/ajp.20250 · Cited by 21
“its contribution to odorant analysis is probably as a minor adjunct to other chemosensory systems [Meredith, 2001; Wysocki & Preti, 2004].”
Olfaction in Nonhuman Primates
Laska, M., & Salazar, L. T. H. (2015) · doi:10.1002/9781118971758.ch27 · Cited by 16
Brann, J. H., & Fadool, D. (2006) · Journal of Experimental Biology · doi:10.1242/jeb.02206 · Cited by 21
“Often, the VNO is considered a detector of nonvolatile odorants, but this assertion is incorrect, since the VNO detects volatile odorants as well (O’Connell and Meredith, 1984; Meredith, 1991; Meredith, 2001; Halpern and Martínez-Marcos, 2003; Trinh and Storm, 2003; LeindersZufall et al., 2004).”
BackgroundAnatomical evidence for an endocrine activity of the vomeronasal organ in humans
Wessels, Q., Hoogland, P. V. J. M., & Vörster, W. (2014) · Clinical Anatomy · doi:10.1002/ca.22382 · Cited by 19
“The existence, however, of these nerves originating from the VNO in adult humans is denied by others (Meredith, 2001).”
BackgroundIntranasal Delivery of Neuropeptides
Veronesi, M. C., Kubek, D. J., & Kubek, M. J. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-310-3_20 · Cited by 19
Human Chemosensory Communication
Pause, B. M. (2017) · Springer eBooks · doi:10.1007/978-3-319-26932-0_52 · Cited by 27
Rozenkrantz, L., Weissgross, R., Weiss, T., Ravreby, I., Frumin, I., Shushan, S., Gorodisky, L., Reshef, N., Holzman, Y., Pinchover, L., et al. (2020) · eLife · doi:10.7554/elife.55305 · Cited by 16
“Humans may retain a VNO pit on the nasal septum (Trotier et al., 2000), but this structure is considered vestigial in the human nose (Meredith, 2001).”
BackgroundZielinski, B. S., & Hara, T. J. (2006) · Fish physiology · doi:10.1016/s1546-5098(06)25001-5 · Cited by 17
Olfactory Systems in Mate Recognition and Sexual Behavior
Keller, M., Pillon, D., & Bakker, J. (2010) · Vitamins and hormones · doi:10.1016/s0083-6729(10)83014-6 · Cited by 19
“Finally, quite convincing pheromonal effects have been demonstrated in humans who do not have a functional vomeronasal system (Meredith, 2001; Wysocki and Preti, 2004).”
BackgroundFoltán, R., & Šedý, J. (2009) · Head & Face Medicine · doi:10.1186/1746-160x-5-5 · Cited by 17
“Meredith M: Sensory processing in the main and accessory olfactory systems: comparisons and contrasts.”
BackgroundInfluentialGenetic basis of olfactory communication in primates
Mundy, N. I. (2006) · American Journal of Primatology · doi:10.1002/ajp.20252 · Cited by 17
“DOI 10.1002/ajp controversy as to whether the VNO is functional in Catarrhines in general, and in humans in particular [Meredith, 2001].”
BackgroundInfluentialMaking Sense of the Chemical Senses
Gagnon, L., Kupers, R. C., & Ptito, M. (2014) · Multisensory Research · doi:10.1163/22134808-00002461 · Cited by 16
Cappuccio, R. (2005) · Elsevier eBooks · doi:10.1016/b978-012370371-2/50010-x · Cited by 16
Leopold, D. A., & Holbrook, E. H. (2010) · Elsevier eBooks · doi:10.1016/b978-0-323-05283-2.00042-2 · Cited by 16
Poly-L-lactic acid as a facial filler.
Sterling, J. B., & Hanke, C. W. (2005) · PubMed · Cited by 16
Development and Developmental Disorders of the Forebrain
ten Donkelaar, H. J., Lammens, M. M. Y., Cruysberg, J. R. M., Ulzen, K. K.-V., Hori, A., & Shiota, K. (2014) · Springer eBooks · doi:10.1007/978-3-642-54687-7_9 · Cited by 16
The vomeronasal organ – incidence in a Bulgarian population
Stoyanov, G. S., Moneva, K., Sapundzhiev, N. R., et al. (2016) · The Journal of Laryngology & Otology · doi:10.1017/s0022215116000189 · Cited by 15
Sex pheromones are not always attractive: changes induced by learning and illness in mice
Lanuza, E., Martín-Sánchez, A., Marco-Manclús, P., Cádiz-Moretti, B., Fortes-Marco, L., Hernández-Martínez, A., McLean, L., Beynon, R., Hurst, J., & Martínez-García, F. (2014) · Animal Behaviour · doi:10.1016/j.anbehav.2014.08.011 · Cited by 15
“Since humans do not have a functional vomeronasal organ (Meredith, 2001), in this case learning is likely to be mediated by the association of the olfactory cue with other kinds of rewarding stimuli related to sexual activity.”
BackgroundOlfaction and olfactory-mediated behaviour in psychiatric disease models
Huckins, L. M., Logan, D. W., & Sánchez-Andrade, G. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1617-7 · Cited by 15
Fate and Development of Human Vomeronasal Organ - A Microscopic Fetal Study.
Manickavasuki, A., Fenn, T. K. A., Devi, M., Hebzibah, T. D. J., Jamuna, M., & Sundaram, K. (2016) · Journal of clinical and diagnostic research : JCDR · doi:10.7860/jcdr/2016/15930.7373 · Cited by 9
Eisenman, S. F. (2015) · Critical Inquiry · doi:10.1086/684357 · Cited by 13
The clinical significance of the human vomeronasal organ
Bruintjes, T. D., & Bleys, R. L. A. W. (2023) · Surgical and Radiologic Anatomy · doi:10.1007/s00276-023-03101-2 · Cited by 14
“Whether the vomeronasal organ plays a part in receiving olfactory signals in man has been much debated [10, 16].”
BackgroundThe roots of sexual arousal and sexual orientation
Salu, Y. (2010) · Medical Hypotheses · doi:10.1016/j.mehy.2010.10.048 · Cited by 13
“However, it has not been demonstrated that humans naturally use those compounds, or in general, that humans depend on pheromones or olfactory signals to identify a mate or to get aroused [4].”
BackgroundNiimi, K., Horie, S., Yokosuka, M., Kawakami-Mori, F., Tanaka, K., Fukayama, H., & Sahara, Y. (2012) · Brain Research · doi:10.1016/j.brainres.2012.08.050 · Cited by 14
Krajnik, J., Kollndorfer, K., Nenning, K., Lundström, J. N., & Schöpf, V. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00195 · Cited by 13
“The wide range of literature addressing the VNO provides little consensus about the presence of the VNO in humans (for a review, see Meredith, 2001).”
BackgroundEvolution of Chemosensory Receptor Genes in Primates and Other Mammals
Niimura, Y. (2011) · Primatology monographs · doi:10.1007/978-4-431-54011-3_4 · Cited by 11
Changing Senses: Chemosensory Signaling and Primate Evolution
Liman, E. R. (2012) · Advances in experimental medicine and biology · doi:10.1007/978-1-4614-1704-0_13 · Cited by 11
Brain Evolution, Chemosensory Processing, and Behavior
Keverne, E. B. (2004) · Nutrition Reviews · doi:10.1111/j.1753-4887.2004.tb00102.x · Cited by 11
Nose, nasal cavity and paranasal sinuses
(2008) · Elsevier eBooks · doi:10.1016/b978-0-443-06684-9.50040-8 · Cited by 10
Kohl, J. V. (2007) · Journal of Psychology & Human Sexuality · doi:10.1300/j056v18n04_03 · Cited by 8
“Sexual selection requires that communication contribute to the evolutionary “fitness” of both the sender and the receiver (Meredith, 2001).”
BackgroundSensopercepción olfatoria: una revisión
Fuentes, A., Fresno, M. J., Santander, H., Valenzuela, S., Gutiérrez, M. F., & Rodolfo Miralles, L. (2011) · Revista médica de Chile · doi:10.4067/s0034-98872011000300013 · Cited by 18
Is the human skin a pheromone‐producing organ?
Pause, B. (2004) · Journal of Cosmetic Dermatology · doi:10.1111/j.1473-2130.2004.00106.x · Cited by 11
An Assay for Human Chemosignals
Frumin, I., & Sobel, N. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-619-1_27 · Cited by 8
Spors, H., & Sobel, N. (2007) · Neuron · doi:10.1016/j.neuron.2007.08.016 · Cited by 8
“…recording specific electrical surface-responses from the human VNO following administration of putative human pheromones, the work of this group has come under considerable criticism and has yet to be replicated by others (reviewed in Meredith, 2001; Witt and Hummel, 2006; Wysocki and Preti, 2004).”
BackgroundTRPC2 and the Molecular Biology of Pheromone Detection in Mammals
MD, P. D. (2006) · CRC Press eBooks · doi:10.1201/9781420005844-9 · Cited by 9
The Vomeronasal organ in Buffalo
Abbasi, M. (2007) · Italian Journal of Animal Science · doi:10.4081/ijas.2007.s2.991 · Cited by 8
“In animals, the cartilaginous capsule displays miscellaneous morphologies (oval, pear-shaped and triangular) in cross profile in different regions of the organ (Abdolmaali et al.,2001; Curtis et al.,2001;Knetch et al.,2001 and Lindsay et al 1978).”
BackgroundAnimal Perception Including Differences With Humans
Scanes, C. G. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805247-1.00001-0 · Cited by 8
The Sense of Smell: Role of the Olfactory System in Social Behavior
Bakker, J., Leinders‐Zufall, T., & Chamero, P. (2022) · Springer eBooks · doi:10.1007/978-3-030-88832-9_29 · Cited by 8
Controversies on the human vomeronasal system.
Martı́nez-Marcos, A. (2001) · Hispana · Cited by 7
McGuigan, M. (2007) · Homeopathy · doi:10.1016/j.homp.2007.01.003 · Cited by 7
Physiologie, exploration et troubles de l'olfaction
Bonfils, P. (2007) · Encyclopédie médico-chirurgicale. Oto-rhino-laryngologie · doi:10.1016/s0246-0351(07)46954-9 · Cited by 7
The Sense of Smell: Role of the Olfactory System in Social Behavior
Bakker, J., Leinders‐Zufall, T., & Chamero, P. (2021) · Springer eBooks · doi:10.1007/978-1-4614-6434-1_29-4 · Cited by 6
Study on the Morphology and Frequency of the Vomeronasal Organ in Humans
Carvalho, M. D. F. P., Alves, A. L., & Barros, M. D. (2008) · International Journal of Morphology · doi:10.4067/s0717-95022008000200006 · Cited by 6
“Some authors have indicated the presence of cells similar to bipolar neurons, between the epithelial cells (Monti-Bloch et al.; Meredith, 2001).”
BackgroundGustatory and Olfactory Sensory Transduction
Roper, S. D. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-387738-3.00039-1 · Cited by 6
Zufall, F., Leinders‐Zufall, T., & Puché, A. C. (2008) · Elsevier eBooks · doi:10.1016/b978-012370880-9.00128-6 · Cited by 6
Spielman, A., & Lischka, F. W. (2004) · Encyclopedia of Gastroenterology · doi:10.1016/b0-12-386860-2/00685-7 · Cited by 6
Hummel, T. R., Schultz, S., Witt, M., & Hatt, H. H. (2011) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2011.05.002 · Cited by 5
Brain Development and Sexual Orientation
Balthazart, J. (2012) · Colloquium Series on The Developing Brain · doi:10.4199/c00064ed1v01y201208dbr008 · Cited by 5
Yoo, S., Ryu, S., Kim, S., Golebiowski, J., Han, H. S., & Moon, C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.04212-7 · Cited by 5
Enlarged vomeronasal organ in a child
Zosel, A. E., Smith, M. M., Smith, T. L., & Castillo, M. (2004) · Clinical Imaging · doi:10.1016/s0899-7071(03)00242-0 · Cited by 5
“It senses peripheral inputs, is involved in chemical communications between animals and is described as a bilateral membranous structure located at the base of the anterior nasal septum in most mammalian species [1,2].”
BackgroundVOMERONASAL ORGAN IN DOMESTIC ANIMALS (A SHORT SURVEY)
Kostov, D. (2007) · Bulgarian Portal for Open Science · Cited by 4
Vespers and vampires: A lifelong microscopic search for the smallest of things
Smith, T. D. (2022) · The Anatomical Record · doi:10.1002/ar.24907 · Cited by 4
“The structure has been the subject of endless fascination and speculation (for appropriately thoughtful appraisals of the likelihood of functionality in humans, see Meredith, 2001, and Wysocki & Preti, 2004).”
Human pheromones: An analysis of misconceptions, problems and study perspectives (review)
Khaustov, S. A., & Dubynin, V. A. (2022) · Science for Education Today · doi:10.15293/2658-6762.2202.09 · Cited by 4
Lectin histochemistry of the olfactory mucosa of Korean native cattle, Bos taurus coreanae
Jang, S., Kim, B., Lee, J., et al. (2022) · Journal of Veterinary Science · doi:10.4142/jvs.22184 · Cited by 4
“The olfactory mucosa (OM), positioned at the caudal/posterior roof of the nasal cavity, and the vomeronasal organ (VNO), located at the base of the nasal septum or on the roof of the mouth, are the organs comprising these two systems [2,3].”
BackgroundSwelling of Erectile Nasal Tissue Induced by Human Sexual Pheromone.
Mazzatenta, A., Luca, C. D., Tano, A. D., Cacchio, M., Giulio, C. D., & Pokorski, M. (2016) · Advances in Experimental Medicine and Biology · doi:10.1007/5584_2015_190 · Cited by 4
Maynard, R. L., & Downes, N. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-811837-5.00010-1 · Cited by 4
La controverse de l’attirance sexuelle par les phéromones chez l’être humain
Simard, D. (2014) · Sexologies · doi:10.1016/j.sexol.2013.12.012 · Cited by 4
“Le professeur de biologie et de neurosciences Michael Meredith, de l’université de l’État de Floride, a soulevé le problème dans son article « Human vomeronasal organ: A critical review of best and worst cases » publié en 2001 dans la revue Chemical Senses (Meredith, 2001).”
BackgroundThe Vomeronasal (Jacobson's) Organ
Coelho, D. H., & Yanagisawa, E. (2005) · Ear Nose & Throat Journal · doi:10.1177/014556130508400703 · Cited by 4
Thermal signatures of human pheromones in sexual and reproductive behaviourPreprint
Mazzatenta, A., Romani, G. L., Tommasi, L., & Merla, A. (2010) · Nature Precedings · doi:10.1038/npre.2010.4477.1 · Cited by 4
“However, pheromone-mediated sexual communication in humans has not been investigated comprehensively, generally because of its non-conscious, concealed nature and the neglected functions of the vomeronasal organ (Jacob et al, 2001b; Monti-Bloch et al., 1998; Meredith, 2001; Wysocki and Preti, 2004).”
BackgroundIntroduction to the special issue on ‘Olfaction, Sex, and Behavior’
Baum, M. J. (2004) · Hormones and Behavior · doi:10.1016/j.yhbeh.2004.06.003 · Cited by 4
TRPC2 and the Molecular Biology of Pheromone Detection in Mammals
Dulac, C. G., & Liman, E. R. (2006) · Frontiers in neuroscience · doi:10.1201/9781420005844.ch3 · Cited by 3
Evidence for accessory chemosensory cells in the adult human nasal cavity
Gebhart, V. M., Rodewald, A., Wollbaum, E., Hertel, K., Bitter, T., & Jirikowski, G. F. (2019) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2019.101732 · Cited by 3
Surgical Anatomy and Physiology of the Nose
Guyuron, B. (2012) · Elsevier eBooks · doi:10.1016/b978-1-4160-3751-4.00001-2 · Cited by 3
Wake up and smell the conspecific!
Holy, T. E. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00232-7 · Cited by 3
High Throughput Receptor Screening Assays
Veithen, A., Philippeau, M., & Chatelain, P. (2017) · Springer eBooks · doi:10.1007/978-3-319-26932-0_22 · Cited by 4
The trade-off between the olfactory bulb and eyeball volume in precocious puberty
Karaoğlan, M., Er, H. Ç., Aytaç, E. H., & Keskın, M. (2020) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem-2019-0450 · Cited by 3
Pheromonal Regulation of Male Sexuality
Mazzatenta, A., Mazzatenta, D., & Cellerino, A. (2011) · doi:10.1002/9781119963820.ch2 · Cited by 3
Aujard, F., Schilling, A., & Perret, M. (2005) · Brain Research · doi:10.1016/j.brainres.2005.02.056 · Cited by 3
Decoster, L., Trova, S., Zucca, S., Gouveia, A., Bulk, J., Ternier, G., Lhomme, T., Legrand, A., Boehm, U., Hrabovszky, E., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-3115610/v1 · Cited by 3
Oleszkiewicz, A., Suhle, P., Haehner, A., & Croy, I. (2021) · Physiology & Behavior · doi:10.1016/j.physbeh.2021.113458 · Cited by 2
“chemical signal to both parties [2] and distinguished four functional groups of pheromones, namely primers, signalers, modulators and”
Background(E)-1,2-Difluoroethylene (HFO-1132E)
Occupational Alliance for Risk Science (OARS), & (TERA), T. E. F. R. A. (2022) · Toxicology and Industrial Health · doi:10.1177/07482337221111674 · Cited by 2
“The VNO is poorly developed or absent in humans (Meredith, 2001).”
BackgroundPheromones and behaviour of rabbits (Oryctolagus cuniculus): a review
Barrionuevo, R., Álvarez, J., Acción, A., Yáñez, U., Sánchez-Quinteiro, P., Martínez, P., Villamayor, P., Becerra, J. J., Peña, A. I., Herradón, P. G., et al. (2025) · World Rabbit Science · doi:10.4995/wrs.2025.22920 · Cited by 1
Electron Microscopy and the Nose
Hayran, M. (2013) · Springer eBooks · doi:10.1007/978-3-642-37250-6_31 · Cited by 2
Kohlmeier, M. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-387784-0.00001-8 · Cited by 2
Relating breath malodour to food constituents and oral health
Greenman, J., & Saad, S. (2009) · Elsevier eBooks · doi:10.1533/9781845696290.2.100 · Cited by 2
Neurotransmitter candidates in the vomeronasal organ of the rat
Uddman, R., Malm, L., & Cardell, L. (2007) · Acta Oto-Laryngologica · doi:10.1080/00016480601110220 · Cited by 2
“The vomeronasal organ (VNO) is a peripheral chemosensory structure found in most vertebrates [1].”
BackgroundAssociation Study of Human VN1R1 Pheromone Receptor Gene Alleles and Gender
Mitropoulos, C., Papachatzopoulou, A., Menounos, P., Kolonelou, C., Pappa, M., Bertolis, G., Gerou, S., & Patrinos, G. (2007) · Genetic Testing · doi:10.1089/gte.2006.0516 · Cited by 3
“…primates the VNO controls the guiding the migration of luteinizing hormone-releasing hormone neurons to the hypothalamus, it degenerates just before birth so that adults possess only ves-tigial VNO function (Meredith, 2001) and have significantly reduced ability or inability to detect pheromones.”
Mammalian Olfactory and Vomeronasal Receptor Families
Niimura, Y., Ihara, S., & Touhara, K. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-809324-5.24175-8 · Cited by 4
Osteopathische Medizin – Wo bleibt der Beweis?
Schleusener, R. (2022) · Osteopathische Medizin · doi:10.1016/s1615-9071(22)00081-8 · Cited by 2
Metadata
- Authors
- Meredith, M.
- Affiliations
- Florida State University (US)
- Corresponding author
- Meredith, M.
- ORCID
- Meredith, M.
- Venue
- Chemical Senses
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-05-01
- Volume
- 26
- Issue
- 4
- Pages
- 433-445
- ISSN
- 0379-864X (ISSN-L)
- 1464-3553
- OpenAlex
- W2169483875
- Cited by
- 280
- References
- 98
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 5 · 2023: 8 · 2022: 10 · 2021: 8 · 2020: 7 · 2019: 12 · 2018: 7 · 2017: 8 · 2016: 7 · 2015: 14 · 2014: 13 · 2013: 13 · 2012: 10
- FWCI
- 1.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Senses (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r01dc000906-06)
- National Institute on Deafness and Other Communication Disorders (DC00906)
- Topics
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Life Sciences › Neuroscience › Sensory Systems › Ion Channels and Receptors
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Chemical Sensor Technologies
- Keywords
- vomeronasal organ, pheromone communication, chemical communication, vomeronasal system, olfaction
- MeSH terms
- Animals, Chemotactic Factors, Electrophysiology, Epithelium, Humans, Pheromones, Vomeronasal Organ, Autocrine Communication
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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