Markers of Human Skeletal Muscle Mitochondrial Biogenesis and Quality Control: Effects of Age and Aerobic Exercise Training

Exercise capacity and mortality among men referred for exercise testing

Myers, J., Prakash, M., Froelicher, V., Do, D., Partington, S., & Atwood, J. E. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa011858 · Cited by 4,114 · see citing works

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601963 · Cited by 3,082 · see citing works

Adaptations of skeletal muscle to endurance exercise and their metabolic consequences

Holloszy, J. O., & Coyle, E. F. (1984) · Journal of Applied Physiology · doi:10.1152/jappl.1984.56.4.831 · Cited by 1,985 · see citing works

Invited Review: Aging and sarcopenia

Doherty, T. J. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00347.2003 · Cited by 1,764 · see citing works

Biochemical Adaptations in Muscle

Holloszy, J. O. (1967) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)96046-1 · Cited by 1,517 · see citing works

Decline in skeletal muscle mitochondrial function with aging in humans

Short, K. R., Bigelow, M. L., Kahl, J., Singh, R., Coenen-Schimke, J., Raghavakaimal, S., & Nair, K. S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501559102 · Cited by 1,333 · see citing works

Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging

Green, D. R., Galluzzi, L., & Kroemer, G. (2011) · Science · doi:10.1126/science.1201940 · Cited by 1,245 · see citing works

Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

Chen, H., Vermulst, M., Wang, Y. E., Chomyn, A., Prolla, T. A., McCaffery, J. M., & Chan, D. C. (2010) · Cell · doi:10.1016/j.cell.2010.02.026 · Cited by 1,211 · see citing works

Mitofusin-2 Determines Mitochondrial Network Architecture and Mitochondrial Metabolism

Bach, D., Pich, S., Soriano, F. X., Vega, N., Baumgartner, B., Oriola, J., Daugaard, J. R., Lloberas, J., Camps, M., Zierath, J. R., et al. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m212754200 · Cited by 832 · see citing works

Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity

Ishihara, N., Eura, Y., & Mihara, K. (2004) · Journal of Cell Science · doi:10.1242/jcs.01565 · Cited by 731 · see citing works

A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy

Ruas, J. L., White, J. P., Rao, R. R., Kleiner, S., Brannan, K. T., Harrison, B. C., Greene, N. P., Wu, J., Estall, J. L., Irving, B. A., et al. (2012) · Cell · doi:10.1016/j.cell.2012.10.050 · Cited by 677 · see citing works

Oxidative capacity and ageing in human muscle

Conley, K. E., Jubrias, S. A., & Esselman, P. C. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.t01-1-00203.x · Cited by 651 · see citing works

Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view

Twig, G., Hyde, B. B., & Shirihai, O. S. (2008) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2008.05.001 · Cited by 646 · see citing works

Impact of Aerobic Exercise Training on Age-Related Changes in Insulin Sensitivity and Muscle Oxidative Capacity

Short, K. R., Vittone, J. L., Bigelow, M. L., Proctor, D. N., Rizza, R. A., Coenen-Schimke, J. M., & Nair, K. S. (2003) · Diabetes · doi:10.2337/diabetes.52.8.1888 · Cited by 631 · see citing works

Endurance Exercise as a Countermeasure for Aging

Lanza, I. R., Short, D. K., Short, K. R., Raghavakaimal, S., Basu, R., Joyner, M. J., McConnell, J. P., & Nair, K. S. (2008) · Diabetes · doi:10.2337/db08-0349 · Cited by 582 · see citing works

Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing

Breen, L., & Phillips, S. M. (2011) · Nutrition & Metabolism · doi:10.1186/1743-7075-8-68 · Cited by 576 · see citing works

Effect of age on <i>in vivo</i> rates of mitochondrial protein synthesis in human skeletal muscle

Rooyackers, O. E., Adey, D. B., Ades, P. A., & Nair, K. S. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.26.15364 · Cited by 564 · see citing works

Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle: Molecular responses during mitochondrial biogenesis

Perry, C. G. R., Lally, J., Holloway, G. P., Heigenhauser, G. J. F., Bonen, A., & Spriet, L. L. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.199448 · Cited by 559 · see citing works

New insights into the role of mitochondria in aging: mitochondrial dynamics and more

Seo, A. Y., Joseph, A.-M., Dutta, D., Hwang, J. C. Y., Aris, J. P., & Leeuwenburgh, C. (2010) · Journal of Cell Science · doi:10.1242/jcs.070490 · Cited by 522 · see citing works

Age and aerobic exercise training effects on whole body and muscle protein metabolism

Short, K. R., Vittone, J. L., Bigelow, M. L., Proctor, D. N., & Nair, K. S. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00366.2003 · Cited by 470 · see citing works

Mitochondrial DNA–Deletion Mutations Accumulate Intracellularly to Detrimental Levels in Aged Human Skeletal Muscle Fibers

Bua, E., Johnson, J., Herbst, A., Delong, B., McKenzie, D., Salamat, S., & Aiken, J. M. (2006) · The American Journal of Human Genetics · doi:10.1086/507132 · Cited by 442 · see citing works

Mitofusins 1/2 and ERRα expression are increased in human skeletal muscle after physical exercise

Cartoni, R., Léger, B., Hock, M. B., Praz, M., Crettenand, A., Pich, S., Ziltener, J., Luthi, F., Dériaz, O., Zorzano, A., et al. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.092031 · Cited by 406 · see citing works

The impact of aging on mitochondrial function and biogenesis pathways in skeletal muscle of sedentary high- and low-functioning elderly individuals

Joseph, A., Adhihetty, P. J., Buford, T. W., Wohlgemuth, S. E., Lees, H. A., Nguyen, L. M. ‐., Aranda, J. M., Sandesara, B. D., Pahor, M., Manini, T. M., et al. (2012) · Aging Cell · doi:10.1111/j.1474-9726.2012.00844.x · Cited by 395 · see citing works

Changes in lower limb muscle cross‐sectional area and tissue fluid volume after transition from standing to supine

Berg, H. E., Tedner, B., & Tesch, P. A. (1993) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1993.tb09573.x · Cited by 366 · see citing works

Evidence for a Mitochondrial Regulatory Pathway Defined by Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α, Estrogen-Related Receptor-α, and Mitofusin 2

Soriano, F. X., Liesa, M., Bach, D., Chan, D. C., Palacín, M., & Zorzano, A. (2006) · Diabetes · doi:10.2337/db05-0509 · Cited by 343 · see citing works

Decline with age of the respiratory chain activity in human skeletal muscle

Boffoli, D., Scacco, S. C., Vergari, R., Solarino, G., Santacroce, G., & Papa, S. (1994) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/0925-4439(94)90061-2 · Cited by 341 · see citing works

Exercise Capacity and Mortality in Older Men: A 20-Year Follow-Up Study

Kokkinos, P., Myers, J., Faselis, C., Panagiotakos, D. B., Doumas, M., Pittaras, A., Manolis, A., Kokkinos;, J. P., Karasik, P., Greenberg, M., et al. (2010) · Circulation · doi:10.1161/circulationaha.110.938852 · Cited by 328 · see citing works

Skeletal muscle mitochondrial energetics are associated with maximal aerobic capacity and walking speed in older adults

Coen, P. M., Jubrias, S. A., Distefano, G., Amati, F., Mackey, D. C., Glynn, N. W., Manini, T. M., Wohlgemuth, S. E., Leeuwenburgh, C., Cummings, S. R., et al. (2013) · The Journals of Gerontology: Series A · doi:10.1093/gerona/gls196 · Cited by 323 · see citing works

Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins

Ling, C., Poulsen, P., Carlsson, E., Ridderstråle, M., Almgren, P., Wojtaszewski, J. F. P., Beck‐Nielsen, H., Groop, L., & Vaag, A. A. (2004) · Journal of Clinical Investigation · doi:10.1172/jci200421889 · Cited by 300 · see citing works

Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins

Ling, C., Poulsen, P., Carlsson, E., Ridderstråle, M., Almgren, P., Wojtaszewski, J., Beck-Nielsen, H., Groop, L., & Vaag, A. (2004) · Journal of Clinical Investigation · doi:10.1172/jci21889 · Cited by 300 · see citing works

The effect of intensive endurance exercise training on body fat distribution in young and older men

Schwartz, R. S., Shuman, W. P., Larson, V., Cain, K. C., Fellingham, G. W., Beard, J. C., Kahn, S. E., Stratton, J. R., Cerqueira, M. D., & Abrass, I. B. (1991) · Metabolism · doi:10.1016/0026-0495(91)90239-s · Cited by 275 · see citing works

The Effect of Aging on Human Skeletal Muscle Mitochondrial and Intramyocellular Lipid Ultrastructure

Crane, J. D., Devries, M. C., Safdar, A., Hamadeh, M. J., & Tarnopolsky, M. A. (2010) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glp179 · Cited by 262 · see citing works

Aerobic exercise training improves whole muscle and single myofiber size and function in older women

Harber, M. P., Konopka, A. R., Douglass, M. D., Minchev, K., Kaminsky, L. A., Trappe, T. A., & Trappe, S. W. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00354.2009 · Cited by 242 · see citing works

Skeletal muscle aging and the mitochondrion

Johnson, M. L., Robinson, M. M., & Nair, K. S. (2013) · Trends in Endocrinology &amp; Metabolism · doi:10.1016/j.tem.2012.12.003 · Cited by 233 · see citing works

Aerobic exercise training induces skeletal muscle hypertrophy and age-dependent adaptations in myofiber function in young and older men

Harber, M. P., Konopka, A. R., Undem, M. K., Hinkley, J. M., Minchev, K., Kaminsky, L. A., Trappe, T. A., & Trappe, S. W. (2012) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00786.2012 · Cited by 218 · see citing works

Aberrant mitochondrial homeostasis in the skeletal muscle of sedentary older adults

Safdar, A., Hamadeh, M. J., Kaczor, J. J., Raha, S., deBeer, J., & Tarnopolsky, M. A. (2010) · PLoS ONE · doi:10.1371/journal.pone.0010778 · Cited by 217 · see citing works

Body composition, fitness, and metabolic health during strength and endurance training and their combination in middle-aged and older women

Sillanpää, E., Laaksonen, D. E., Häkkinen, A., Karavirta, L., Jensen, B., Kraemer, W. J., Nyman, K., & Häkkinen, K. (2009) · European Journal of Applied Physiology · doi:10.1007/s00421-009-1013-x · Cited by 186 · see citing works

Skeletal muscle mass and the reduction ofV˙ o 2 max in trained older subjects

Proctor, D. N., & Joyner, M. J. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.82.5.1411 · Cited by 186 · see citing works

Once weekly combined resistance and cardiovascular training in healthy older men

IZQUIERDO, M., IBA??EZ, J., H??KKINEN, K., KRAEMER, W. J., LARRI??N, J. L., & GOROSTIAGA, E. M. (2004) · Medicine &amp; Science in Sports &amp; Exercise · doi:10.1249/01.mss.0000117897.55226.9a · Cited by 185 · see citing works

Effects of combined resistance and cardiovascular training on strength, power, muscle cross-sectional area, and endurance markers in middle-aged men

Izquierdo, M., Häkkinen, K., Ibáñez, J., Kraemer, W. J., & Gorostiaga, E. M. (2005) · European Journal of Applied Physiology · doi:10.1007/s00421-004-1280-5 · Cited by 155 · see citing works

Age-Associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training

Koltai, E., Hart, N., Taylor, A. W., Goto, S., Ngo, J. K., Davies, K. J. A., & Radak, Z. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00337.2011 · Cited by 152 · see citing works

Response of mitochondrial fusion and fission protein gene expression to exercise in rat skeletal muscle

Ding, H., Jiang, N., Liu, H., Liu, X., Liu, D., Zhao, F., Wen, L., Liu, S., Ji, L. L., & Zhang, Y. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.08.007 · Cited by 149 · see citing works

Chronic Endurance Exercise Induces Quadriceps Nitrosative Stress in Patients with Severe COPD

Barreiro, E., Rabinovich, R., Marin-Corral, J., Barbera, J. A., Gea, J., & Roca, J. (2008) · Thorax · doi:10.1136/thx.2008.105163 · Cited by 133 · see citing works

The changing shape of mitochondrial apoptosis

Wasilewski, M., & Scorrano, L. (2009) · Trends in Endocrinology and Metabolism · doi:10.1016/j.tem.2009.03.007 · Cited by 129 · see citing works

Reduction in Reactive Oxygen Species Production by Mitochondria From Elderly Subjects With Normal and Impaired Glucose Tolerance

Ghosh, S., Lertwattanarak, R., Lefort, N., Molina-Carrion, M., Joya-Galeana, J., Bowen, B. P., Garduno-Garcia, J. D. J., Abdul-Ghani, M., Richardson, A., DeFronzo, R. A., et al. (2011) · Diabetes · doi:10.2337/db11-0121 · Cited by 128 · see citing works

Molecular Adaptations to Aerobic Exercise Training in Skeletal Muscle of Older Women

Konopka, A. R., Douglass, M. D., Kaminsky, L. A., Jemioło, B., Trappe, T. A., Trappe, S. W., & Harber, M. P. (2010) · The Journals of Gerontology Series A · doi:10.1093/gerona/glq109 · Cited by 123 · see citing works

Correlation between mitochondrial DNA 4977-bp deletion and respiratory chain enzyme activities in aging human skeletal muscles

Lezza, A. M. S., Boffoli, D., Scacco, S., Cantatore, P., & Gadaleta, M. N. (1994) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1994.2732 · Cited by 118 · see citing works

Mitochondrial Biogenesis and Fragmentation as Regulators of Muscle Protein Degradation

Romanello, V., & Sandri, M. (2010) · Current Hypertension Reports · doi:10.1007/s11906-010-0157-8 · Cited by 117 · see citing works

The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscle

Bori, Z., Zhao, Z., Koltai, E., Fatouros, I. G., Jamurtas, A. Z., Douroudos, I. I., Terzis, G., Chatzinikolaou, A., Sovatzidis, A., Draganidis, D., et al. (2012) · Experimental Gerontology · doi:10.1016/j.exger.2012.03.004 · Cited by 108 · see citing works

Effect of exercise intervention on thigh muscle volume and anatomical cross‐sectional areas—Quantitative assessment using MRI

Hudelmaier, M. I., Wirth, W., Himmer, M., Ring‐Dimitriou, S., Sänger, A. M., & Eckstein, F. (2010) · Magnetic Resonance in Medicine · doi:10.1002/mrm.22550 · Cited by 69 · see citing works

Human mRNA Response to Exercise and Temperature

Slivka, D. R., Dumke, C. L., Tucker, T., Cuddy, J. S., & Ruby, B. C. (2011) · International Journal of Sports Medicine · doi:10.1055/s-0031-1287799 · Cited by 64 · see citing works

Can Aerobic Training Improve Muscle Strength and Power in Older Men?

Lovell, D. I., Cuneo, R. C., & Gass, G. C. (2010) · Journal of Aging and Physical Activity · doi:10.1123/japa.18.1.14 · Cited by 52 · see citing works

Myosin Heavy Chain Plasticity in Aging Skeletal Muscle With Aerobic Exercise Training

Konopka, A. R., Trappe, T. A., Jemioło, B., Trappe, S. W., & Harber, M. P. (2011) · The Journals of Gerontology Series A · doi:10.1093/gerona/glr088 · Cited by 48 · see citing works

Inter-individual variability in adaptation of the leg muscles following a standardised endurance training programme in young women

McPhee, J. S., Williams, A. G., Degens, H., & Jones, D. A. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1454-2 · Cited by 39 · see citing works

Endurance exercise as a countermeasure for aging. Diabetes 2008;57:2933–2942

Lanza, I. R., Short, D. C., Short, K., Raghavakaimal, S., Basu, R., Mj, J., McConnell, J. P., & Nair, K. (2012) · Diabetes · doi:10.2337/db12-er10 · Cited by 37 · see citing works

Evaluation of Movement Speed and Reaction Time as Predictors of All-Cause Mortality in Men

Metter, E. J., Schrager, M., Ferrucci, L., & Talbot, L. A. (2005) · The Journals of Gerontology Series A · doi:10.1093/gerona/60.7.840 · Cited by 36 · see citing works

Random mtDNA deletions and functional consequence in aged human skeletal muscle

Chabi, B., de Camaret, B. M., Chevrollier, A., Boisgard, S., & Stepien, G. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.04.153 · Cited by 33 · see citing works

Resistance Exercise Reduces Muscular Substrates in Women

Harber, M. P., Crane, J. D., Douglass, M., Weindel, K., Trappe, T. A., Trappe, S. W., & Fink, W. (2008) · International Journal of Sports Medicine · doi:10.1055/s-2007-989442 · Cited by 32 · see citing works

Substrate use and biochemical response to a 3,211-km bicycle tour in trained cyclists

Slivka, D. R., Dumke, C. L., Hailes, W. S., Cuddy, J. S., & Ruby, B. C. (2011) · European Journal of Applied Physiology · doi:10.1007/s00421-011-2129-3 · Cited by 12 · see citing works

Effects of Exercise and Aging on Skeletal MusclePreprint

Distéfano, G., & Goodpaster, B. H. (2017) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a029785 · Cited by 491 · see citing works

Exercise Promotes Healthy Aging of Skeletal Muscle

Cartee, G. D., Hepple, R. T., Bamman, M. M., & Zierath, J. R. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2016.05.007 · Cited by 483 · see citing works

Effects of Exercise to Improve Cardiovascular Health

Pinckard, K. M., Baskin, K. K., & Stanford, K. I. (2019) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2019.00069 · Cited by 477 · see citing works

Skeletal Muscle Hypertrophy After Aerobic Exercise Training

Konopka, A. R., & Harber, M. P. (2014) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000007 · Cited by 320 · see citing works

Enhanced Respiratory Chain Supercomplex Formation in Response to Exercise in Human Skeletal Muscle

Greggio, C., Jha, P., Kulkarni, S. S., Lagarrigue, S., Broskey, N. T., Boutant, M., Wang, X., Conde Alonso, S., Ofori, E., Auwerx, J., et al. (2017) · Cell Metabolism · doi:10.1016/j.cmet.2016.11.004 · Cited by 286 · see citing works

Skeletal muscle aging: influence of oxidative stress and physical exercise

Gomes, M. J., Martinez, P. F., Pagan, L. U., Damatto, R. L., Mariano Cezar, M. D., Ruiz Lima, A. R., Okoshi, K., & Okoshi, M. P. (2017) · Oncotarget · doi:10.18632/oncotarget.14670 · Cited by 285 · see citing works

Muscle fiber type diversification during exercise and regeneration

Qaisar, R., Bhaskaran, S., & Van Remmen, H. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.03.025 · Cited by 283 · see citing works

Mitochondrial Dynamics and Mitophagy in Skeletal Muscle Health and Aging

Leduc-Gaudet, J.-P., Hussain, S. N. A., Barreiro, E., & Gouspillou, G. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22158179 · Cited by 268 · see citing works

Training-Induced Changes in Mitochondrial Content and Respiratory Function in Human Skeletal Muscle

Granata, C., Jamnick, N. A., & Bishop, D. J. (2018) · Sports Medicine · doi:10.1007/s40279-018-0936-y · Cited by 247 · see citing works

Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis

Mora, A. L., Bueno, M., & Rojas, M. M. (2017) · Journal of Clinical Investigation · doi:10.1172/jci87440 · Cited by 234 · see citing works

The role of declining adaptive homeostasis in ageing

Pomatto, L. C. D., & Davies, K. J. A. (2017) · The Journal of Physiology · doi:10.1113/jp275072 · Cited by 223 · see citing works

Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans

Gouspillou, G., Sgarioto, N., Kapchinsky, S., Purves‐Smith, F., Norris, B., Pion, C. H., Barbat‐Artigas, S., Lemieux, F., Taivassalo, T., Morais, J. A., et al. (2014) · The FASEB Journal · doi:10.1096/fj.13-242750 · Cited by 217 · see citing works

Skeletal Muscle Mitochondrial Content, Oxidative Capacity, and Mfn2 Expression Are Reduced in Older Patients With Heart Failure and Preserved Ejection Fraction and Are Related to Exercise Intolerance

Molina, A. J. A., Bharadwaj, M. S., Horn, C. V., Nicklas, B. J., Lyles, M. F., Eggebeen, J., Haykowsky, M. J., Brubaker, P. H., & Kitzman, D. W. (2016) · JACC Heart Failure · doi:10.1016/j.jchf.2016.03.011 · Cited by 209 · see citing works

Age-related changes in skeletal muscle: changes to life-style as a therapy

McCormick, R., & Vasilaki, A. (2018) · Biogerontology · doi:10.1007/s10522-018-9775-3 · Cited by 210 · see citing works

Skeletal muscle homeostasis and plasticity in youth and ageing: impact of nutrition and exercise

Brook, M. S., Wilkinson, D. J., Phillips, B. E., Pérez‐Schindler, J., Philp, A., Smith, K., & Atherton, P. J. (2015) · Acta Physiologica · doi:10.1111/apha.12532 · Cited by 193 · see citing works

Beneficial effects of exercise on age‐related mitochondrial dysfunction and oxidative stress in skeletal muscle

Joseph, A., Adhihetty, P. J., & Leeuwenburgh, C. (2016) · The Journal of Physiology · doi:10.1113/jp270659 · Cited by 186 · see citing works

Role of the mitochondrial DNA replication machinery in mitochondrial DNA mutagenesis, aging and age-related diseases

DeBalsi, K. L., Hoff, K. E., & Copeland, W. C. (2017) · Ageing Research Reviews · doi:10.1016/j.arr.2016.04.006 · Cited by 180 · see citing works

Biochemical Pathways of Sarcopenia and Their Modulation by Physical Exercise: A Narrative Review

Ziaaldini, M. M., Marzetti, E., Picca, A., & Murlasits, Z. (2017) · Frontiers in Medicine · doi:10.3389/fmed.2017.00167 · Cited by 167 · see citing works

The ageing neuromuscular system and sarcopenia: A mitochondrial perspective

Rygiel, K. A., Picard, M., & Turnbull, D. M. (2016) · The Journal of Physiology · doi:10.1113/jp271212 · Cited by 165 · see citing works

Antioxidant and Adaptative Response Mediated by Nrf2 during Physical Exercise

Vargas-Mendoza, N., Morales‐González, Á., Madrigal‐Santillán, E., Madrigal‐Bujaidar, E., Álvarez‐González, I., García-Melo, L. F., Anguiano‐Robledo, L., Fregoso-Aguilar, T. A., & Morales‐González, J. A. (2019) · Antioxidants · doi:10.3390/antiox8060196 · Cited by 163 · see citing works

Skeletal Muscle Mitochondria in the Elderly: Effects of Physical Fitness and Exercise Training

Broskey, N. T., Greggio, C., Boss, A., Boutant, M., Dwyer, A., Schlueter, L., Hans, D., Gremion, G., Kreis, R., Boesch, C., et al. (2014) · The Journal of Clinical Endocrinology &amp; Metabolism · doi:10.1210/jc.2013-3983 · Cited by 157 · see citing works

Impact of Aging and Exercise on Mitochondrial Quality Control in Skeletal Muscle

Kim, Y., Triolo, M., & Hood, D. A. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/3165396 · Cited by 158 · see citing works

The impact of ageing, physical activity, and pre‐frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men

St‐Jean‐Pelletier, F., Pion, C. H., Leduc‐Gaudet, J., Sgarioto, N., Zovilé, I., Barbat‐Artigas, S., Reynaud, O., Alkaterji, F., Lemieux, F. C., Grenon, A., et al. (2017) · Journal of Cachexia, Sarcopenia and Muscle · doi:10.1002/jcsm.12139 · Cited by 156 · see citing works

Mitochondrial Involvement and Impact in Aging Skeletal Muscle

Hepple, R. T. (2014) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2014.00211 · Cited by 155 · see citing works

Intensified mitophagy in skeletal muscle with aging is downregulated by PGC-1alpha overexpression in vivo

Yeo, D., Kang, C., Gomez-Cabrera, M. C., Vina, J., & Ji, L. L. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.10.456 · Cited by 137 · see citing works

Frontiers in sarcopenia: Advancements in diagnostics, molecular mechanisms, and therapeutic strategies

Liu, D., Wang, S., Liu, S., Wang, Q., Che, X., & Wu, G. (2024) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2024.101270 · Cited by 134 · see citing works

Human skeletal muscle-specific atrophy with aging: a comprehensive review

Naruse, M., Trappe, S. W., & Trappe, T. A. (2023) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00768.2022 · Cited by 132 · see citing works

Exercise and mitochondrial dynamics: keeping in shape with ROS and AMPK

Trewin, A., Berry, B., & Wojtovich, A. (2018) · Antioxidants · doi:10.3390/antiox7010007 · Cited by 129 · see citing works

Autophagy plays a role in skeletal muscle mitochondrial biogenesis in an endurance exercise-trained condition

Ju, J.-S., Jeon, S.-I., Park, J.-Y., Lee, J.-Y., Lee, S.-C., Cho, K.-J., & Jeong, J.-M. (2016) · The Journal of Physiological Sciences · doi:10.1007/s12576-016-0440-9 · Cited by 125 · see citing works

Principles of Exercise Prescription, and How They Influence Exercise-Induced Changes of Transcription Factors and Other Regulators of Mitochondrial Biogenesis

Granata, C., Jamnick, N. A., & Bishop, D. J. (2018) · Sports Medicine · doi:10.1007/s40279-018-0894-4 · Cited by 127 · see citing works

Exercise training remodels human skeletal muscle mitochondrial fission and fusion machinery towards a pro‐elongation phenotype

Axelrod, C. L., Fealy, C. E., Mulya, A., & Kirwan, J. P. (2018) · Acta Physiologica · doi:10.1111/apha.13216 · Cited by 120 · see citing works

Mitochondrial Function and Mitophagy in the Elderly: Effects of Exercise

Moreira, O. C., Estébanez, B., Martínez‐Flórez, S., Fernández, J. A. D. P., Cuevas, M. J., & González‐Gallego, J. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/2012798 · Cited by 120 · see citing works

Taurine in sports and exercise

Kurtz, J. A., VanDusseldorp, T. A., Doyle, J. A., & Otis, J. S. (2021) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-021-00438-0 · Cited by 117 · see citing works

Impact of Endurance and Resistance Training on Skeletal Muscle Glucose Metabolism in Older Adults

Consitt, L. A., Dudley, C., & Saxena, G. (2019) · Nutrients · doi:10.3390/nu11112636 · Cited by 116 · see citing works

Treatment of volumetric muscle loss in mice using nanofibrillar scaffolds enhances vascular organization and integration

Nakayama, K. H., Quarta, M., Paine, P., Alcazar, C., Karakikes, I., Garcia, V., Abilez, O. J., Calvo, N. S., Simmons, C. S., Rando, T. A., et al. (2019) · Communications Biology · doi:10.1038/s42003-019-0416-4 · Cited by 113 · see citing works

Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training

Konopka, A. R., Asante, A., Lanza, I. R., Robinson, M. M., Johnson, M. L., Dalla Man, C., Cobelli, C., Amols, M. H., Irving, B. A., & Nair, K. S. (2015) · Diabetes · doi:10.2337/db14-1701 · Cited by 112 · see citing works

Distinct patterns of skeletal muscle mitochondria fusion, fission and mitophagy upon duration of exercise training

Arribat, Y., Broskey, N. T., Greggio, C., Boutant, M., Conde Alonso, S., Kulkarni, S. S., Lagarrigue, S., Carnero, E. A., Besson, C., Cantó, C., et al. (2019) · Acta Physiologica · doi:10.1111/apha.13179 · Cited by 112 · see citing works

Mitophagy plays a central role in mitochondrial ageing

Diot, A., Morten, K., & Poulton, J. (2016) · Mammalian Genome · doi:10.1007/s00335-016-9651-x · Cited by 109 · see citing works

Regular Endurance Exercise Promotes Fission, Mitophagy, and Oxidative Phosphorylation in Human Skeletal Muscle Independently of Age

Balan, E., Schwalm, C., Naslain, D., Nielens, H., Francaux, M., & Deldicque, L. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.01088 · Cited by 104 · see citing works

Mitochondrial Dysfunction: A Key Player in Brain Aging and Diseases

Bartman, S., Coppotelli, G., & Ross, J. M. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46030130 · Cited by 101 · see citing works

The role of mitochondrial dynamics and mitophagy in skeletal muscle atrophy: from molecular mechanisms to therapeutic insights

Lei, Y., Gan, M., Qiu, Y., Chen, Q., Wang, X., Liao, T., Zhao, M., Chen, L., Zhang, S., Zhao, Y., et al. (2024) · Cellular & Molecular Biology Letters · doi:10.1186/s11658-024-00572-y · Cited by 100 · see citing works

Mitochondrial Properties in Skeletal Muscle Fiber

Dong, H., & Tsai, S. (2023) · Cells · doi:10.3390/cells12172183 · Cited by 95 · see citing works

Exercise-stimulated FGF23 promotes exercise performance via controlling the excess reactive oxygen species production and enhancing mitochondrial function in skeletal muscle

Li, D.-J., Fu, H., Zhao, T., Ni, M., & Shen, F.-M. (2016) · Metabolism · doi:10.1016/j.metabol.2016.02.009 · Cited by 92 · see citing works

Human Skeletal Muscle Mitochondrial Adaptations Following Resistance Exercise Training

Parry, H. A., Roberts, M. D., & Kavazis, A. N. (2020) · International Journal of Sports Medicine · doi:10.1055/a-1121-7851 · Cited by 92 · see citing works

Preservation of skeletal muscle mitochondrial content in older adults: Relationship between mitochondria, fibre type and high-intensity exercise training

Wyckelsma, V. L., Levinger, I., McKenna, M. J., Formosa, L. E., Ryan, M. T., Petersen, A. C., Anderson, M. J., & Murphy, R. M. (2017) · The Journal of Physiology · doi:10.1113/jp273950 · Cited by 91 · see citing works

Mitochondrial remodeling: Rearranging, recycling, and reprogramming

Gottlieb, R. A., & Bernstein, D. (2016) · Cell Calcium · doi:10.1016/j.ceca.2016.04.006 · Cited by 86 · see citing works

Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging

Johnson, M. L., Irving, B. A., Lanza, I. R., Vendelbo, M. H., Konopka, A. R., Robinson, M. M., Henderson, G. C., Klaus, K. A., Morse, D. M., Heppelmann, C. J. H., et al. (2014) · The Journals of Gerontology Series A · doi:10.1093/gerona/glu221 · Cited by 84 · see citing works

Two weeks of one-leg immobilization decreases skeletal muscle respiratory capacity equally in young and elderly men

Gram, M., Vigelsø, A., Yokota, T., HANSEN, C. N., Helge, J. W., Hey‐Mogensen, M., & Dela, F. (2014) · Experimental Gerontology · doi:10.1016/j.exger.2014.08.013 · Cited by 77 · see citing works

Chronological Age Does not Influence<i>Ex-vivo</i>Mitochondrial Respiration and Quality Control in Skeletal Muscle

Distefano, G., Standley, R. A., Dubé, J. J., Carnero, E. A., Ritov, V. B., Stefanovic-Racic, M., Toledo, F. G. S., Piva, S. R., Goodpaster, B. H., & Coen, P. M. (2016) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glw102 · Cited by 76 · see citing works

Exercise-Induced Mitohormesis for the Maintenance of Skeletal Muscle and Healthspan Extension

Musci, R., Hamilton, K., & Linden, M. (2019) · Sports · doi:10.3390/sports7070170 · Cited by 73 · see citing works

Targeting the molecular & cellular pillars of human aging with exercise

Goh, J., Wong, E. S. P., Soh, J., Maier, A. B., & Kennedy, B. K. (2021) · FEBS Journal · doi:10.1111/febs.16337 · Cited by 73 · see citing works

Beneficial effects of dark chocolate on exercise capacity in sedentary subjects: underlying mechanisms. A double blind, randomized, placebo controlled trial

Taub, P. R., Ramírez‐Sánchez, I., Patel, M., Higginbotham, E., Moreno‐Ulloa, A., Román-Pintos, L. M., Phillips, P., Perkins, G. A., Ceballos, G. M., & Villarreal, F. J. (2016) · Food & Function · doi:10.1039/c6fo00611f · Cited by 71 · see citing works

Exercise improves mitochondrial and redox-regulated stress responses in the elderly: better late than never!

Cobley, J. N., Moult, P. R., Burniston, J. G., Morton, J. P., & Close, G. L. (2014) · Biogerontology · doi:10.1007/s10522-014-9546-8 · Cited by 69 · see citing works

Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults

Mesquita, P. H. C., Lamb, D. A., Parry, H. A., Moore, J. H., Smith, M. A., Vann, C. G., Osburn, S. C., Fox, C. D., Ruple, B. A., Huggins, K. W., et al. (2020) · Physiological Reports · doi:10.14814/phy2.14526 · Cited by 66 · see citing works

Impact of exercise training on muscle mitochondria modifications in older adults: a systematic review of randomized controlled trials

Lippi, L., de Sire, A., Mezian, K., Curci, C., Perrero, L., Turco, A., Andaloro, S., Ammendolia, A., Fusco, N., & Invernizzi, M. (2022) · Aging Clinical and Experimental Research · doi:10.1007/s40520-021-02073-w · Cited by 65 · see citing works

Effects of aging and exercise training on mitochondrial function and apoptosis in the rat heart

No, M., Heo, J., Yoo, S.-Z., Kim, C., Park, D., Kang, J., Seo, D. Y., Han, J., & Kwak, H. (2020) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-020-02357-6 · Cited by 63 · see citing works

What and How Can Physical Activity Prevention Function on Parkinson’s Disease?

Fan, B., Jabeen, R., Bo, B., Guo, C., Meng-jie, H., Zhang, H., Cen, J., Ji, X., & Wei, J. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/4293071 · Cited by 64 · see citing works

Aging alters acetylation status in skeletal and cardiac muscles

Yeo, D., Kang, C., & Ji, L. L. (2020) · GeroScience · doi:10.1007/s11357-020-00171-7 · Cited by 61 · see citing works

Exercise rescues mitochondrial coupling in aged skeletal muscle: a comparison of different modalities in preventing sarcopenia

Harper, C., Gopalan, V., & Goh, J. (2021) · Journal of Translational Medicine · doi:10.1186/s12967-021-02737-1 · Cited by 62 · see citing works

State of Knowledge on Molecular Adaptations to Exercise in Humans: Historical Perspectives and Future Directions

Lavin, K. M., Coen, P. M., Baptista, L. C. P., Bell, M. B., Drummer, D. J., Harper, S. A., Lixandrão, M. E., McAdam, J. S., O’Bryan, S. M., Ramos, S. V., et al. (2022) · Comprehensive physiology · doi:10.1002/cphy.c200033 · Cited by 74 · see citing works

Relationship between intermuscular adipose tissue infiltration and myostatin before and after aerobic exercise training

Konopka, A. R., Wolff, C. A., Suer, M. K., & Harber, M. P. (2018) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00030.2018 · Cited by 59 · see citing works

Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging

Fealy, C. E., Grevendonk, L., Joris Hoeks, J., & Hesselink, M. K. C. (2021) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2021.07.013 · Cited by 58 · see citing works

The influence of aerobic exercise on mitochondrial quality control in skeletal muscle

Philp, A. M., Saner, N. J., Lazarou, M., Ganley, I. G., & Philp, A. (2020) · The Journal of Physiology · doi:10.1113/jp279411 · Cited by 58 · see citing works

Mitochondrial involvement in sarcopenia

Affourtit, C., & Carré, J. E. (2024) · Acta Physiologica · doi:10.1111/apha.14107 · Cited by 58 · see citing works

Manifestations of Age on Autophagy, Mitophagy and Lysosomes in Skeletal Muscle

Triolo, M., & Hood, D. A. (2021) · Cells · doi:10.3390/cells10051054 · Cited by 57 · see citing works

Pleiotropic and multi-systemic actions of physical exercise on PGC-1α signaling during the aging process

Neto, I. V. D. S., Pinto, A. P., Muñoz, V. R., Marqueti, R. D. C., Pauli, J. R., Ropelle, E. R., & da Silva, A. S. R. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.101935 · Cited by 56 · see citing works

Nutritional and Exercise Interventions in Cancer-Related Cachexia: An Extensive Narrative Review

Clemente‐Suárez, V. J., Redondo-Flórez, L., Rubio-Zarapuz, A., Martínez‐Guardado, I., Navarro-Jiménez, E., & Tornero-Aguilera, J. F. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19084604 · Cited by 53 · see citing works

Redox Signaling and Sarcopenia: Searching for the Primary Suspect

Foreman, N. A., Hesse, A. S., & Ji, L. L. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22169045 · Cited by 52 · see citing works

Lysosomal Proteolysis Is Associated With Exercise-Induced Improvement of Mitochondrial Quality Control in Aged Hippocampus

Luo, L., Dai, J.-R., Guo, S., Lu, A.-M., Gao, X., Gu, Y., Zhang, X., Xu, H., Wang, Y., Zhu, Z., et al. (2017) · The Journals of Gerontology Series A · doi:10.1093/gerona/glw242 · Cited by 51 · see citing works

Effects of Acute Exercise on Mitochondrial Function, Dynamics, and Mitophagy in Rat Cardiac and Skeletal Muscles

Yoo, S.-Z., No, M., Heo, J., Park, D., Kang, J., Kim, J.-H., Seo, D. Y., Han, J., Jung, S., & Kwak, H. (2019) · International Neurourology Journal · doi:10.5213/inj.1938038.019 · Cited by 50 · see citing works

Sarcopenia: Tilting the Balance of Protein Homeostasis

Tan, K. T., Ang, S. T., & Tsai, S. (2019) · PROTEOMICS · doi:10.1002/pmic.201800411 · Cited by 49 · see citing works

The importance of mitochondrial quality control for maintaining skeletal muscle function across health span

Sligar, J., Debruin, D. A., Saner, N. J., Philp, A. M., & Philp, A. (2022) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00388.2021 · Cited by 49 · see citing works

Effects of lithium on age-related decline in mitochondrial turnover and function in Caenorhabditis elegans.

Tam, Z.-Y., Gruber, J., Ng, L., Halliwell, B., & Gunawan, R. (2014) · The journals of gerontology. Series A, Biological sciences and medical sciences · doi:10.1093/gerona/glt210 · Cited by 50 · see citing works

Sarcopenia and cachexia: molecular mechanisms and therapeutic interventions

Wang, T., Zhou, D., & Hong, Z. (2025) · MedComm · doi:10.1002/mco2.70030 · Cited by 46 · see citing works

Targeting mitochondrial quality control for treating sarcopenia: lessons from physical exercise

Picca, A., Calvani, R., Leeuwenburgh, C., Coelho‐Júnior, H. J., Bernabei, R., Landi, F., & Marzetti, E. (2018) · Expert Opinion on Therapeutic Targets · doi:10.1080/14728222.2019.1559827 · Cited by 42 · see citing works

Exercise and ageing impact the kynurenine/tryptophan pathway and acylcarnitine metabolite pools in skeletal muscle of older adults

Hinkley, J. M., Yu, G. X., Standley, R. A., Distéfano, G., Tolstikov, V., Narain, N. R., Greenwood, B. P., Karmacharya, S., Kiebish, M. A., Carnero, E. Á., et al. (2023) · The Journal of Physiology · doi:10.1113/jp284142 · Cited by 41 · see citing works

Exercise as Mitochondrial Medicine: How Does the Exercise Prescription Affect Mitochondrial Adaptations to Training?

Bishop, D. J., Lee, M. J.-C., & Picard, M. A. (2024) · Annual Review of Physiology · doi:10.1146/annurev-physiol-022724-104836 · Cited by 42 · see citing works

Impact of Aging and Lifelong Exercise Training on Mitochondrial Function and Network Connectivity in Human Skeletal Muscle

Ringholm, S., Gudiksen, A., Halling, J. F., Qoqaj, A., Rasmussen, P. M., Prats, C., Plomgaard, P., & Pilegaard, H. (2022) · The Journals of Gerontology Series A · doi:10.1093/gerona/glac164 · Cited by 42 · see citing works

PGC-1α-Targeted Therapeutic Approaches to Enhance Muscle Recovery in Aging

Petrocelli, J. J., & Drummond, M. J. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17228650 · Cited by 39 · see citing works

Skeletal Muscle Mitochondrial Energetic Efficiency and Aging

Crescenzo, R., Bianco, F., Mazzoli, A., Giacco, A., Liverini, G., & Iossa, S. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160510674 · Cited by 39 · see citing works

Effects of Pyrroloquinoline Quinone (PQQ) Supplementation on Aerobic Exercise Performance and Indices of Mitochondrial Biogenesis in Untrained Men

Hwang, P. S., Machek, S. B., Cardaci, T. D., Wilburn, D. T., Kim, C. S., Suezaki, E. S., & Willoughby, D. S. (2019) · Journal of the American College of Nutrition · doi:10.1080/07315724.2019.1705203 · Cited by 37 · see citing works

High-intensity aerobic, but not resistance or combined, exercise training improves both cardiometabolic health and skeletal muscle mitochondrial dynamics

Ruegsegger, G. N., Pataky, M. W., Simha, S., Robinson, M. M., Klaus, K. A., & Nair, K. S. (2023) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00405.2023 · Cited by 38 · see citing works

Blunted angiogenesis and hypertrophy are associated with increased fatigue resistance and unchanged aerobic capacity in old overloaded mouse muscle

Ballak, S. B., Busé-Pot, T., Harding, P., Yap, M. H., Deldicque, L., HAAN, A. D., Jaspers, R. T., & Degens, H. (2016) · AGE · doi:10.1007/s11357-016-9894-1 · Cited by 38 · see citing works

Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats

Thirupathi, A., Pieri, B. L. D. S., Queiroz, J. A. M. P., Rodrigues, M. S., Silveira, G. D. B., de Souza, D. R., Luciano, T. F., Silveira, P. C. L., & de Souza, C. T. (2019) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-019-00663-x · Cited by 38 · see citing works

Mitochondria as Nutritional Targets to Maintain Muscle Health and Physical Function During Ageing

Broome, S. C., Whitfield, J., Karagounis, L. G., & Hawley, J. A. (2024) · Sports Medicine · doi:10.1007/s40279-024-02072-7 · Cited by 39 · see citing works

Running‐wheel activity delays mitochondrial respiratory flux decline in aging mouse muscle via a post‐transcriptional mechanism

Stolle, S., Čiapaitė, J., Reijne, A. C., Talarovičová, A., Wolters, J. C., Aguirre‐Gamboa, R., van der Vlies, P., de Lange, K., Neerincx, P. B. T., van der Vries, G. B., et al. (2017) · Aging Cell · doi:10.1111/acel.12700 · Cited by 36 · see citing works

Do exercise-associated genes explain phenotypic variance in the three components of fitness? A Systematic review &amp; Meta-analysis

Chung, H. C., Keiller, D. R., Roberts, J. D., & Gordon, D. A. (2021) · doi:10.1101/2021.03.22.436402 · Cited by 34 · see citing works

Magnetic resonance spectroscopic analysis of multifidus muscles lipid content and association with spinopelvic malalignment in chronic low back pain

Ogon, I., Takebayashi, T., Takashima, H., Morita, T., Yoshimoto, M., Terashima, Y., & Yamashita, T. (2017) · British Journal of Radiology · doi:10.1259/bjr.20160753 · Cited by 34 · see citing works

Myoblast mitochondrial respiration is decreased in chronic binge alcohol administered simian immunodeficiency virus-infected antiretroviral-treated rhesus macaques

Duplanty, A. A., Siggins, R. W., Allerton, T. D., Simon, L., & Molina, P. E. (2018) · Physiological Reports · doi:10.14814/phy2.13625 · Cited by 34 · see citing works

Regulatory role of exercise-induced autophagy for sarcopenia

Liang, J., Zeng, Z., Zhang, Y., & Chen, N. (2020) · Experimental Gerontology · doi:10.1016/j.exger.2019.110789 · Cited by 33 · see citing works

Effect of Aerobic Exercise Training and Deconditioning on Oxidative Capacity and Muscle Mitochondrial Enzyme Machinery in Young and Elderly Individuals

Fritzen, A. M., Andersen, S., Qadri, K. A. N., Thøgersen, F. B., Krag, T. O. B., Ørngreen, M. C., Vissing, J., & Jeppesen, T. D. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9103113 · Cited by 33 · see citing works

Improved muscle function and quality after diet intervention with leucine-enriched whey and antioxidants in antioxidant deficient aged mice

van Dijk, M., Dijk, F. J., Bunschoten, A., van Dartel, D. A. M., van Norren, K., Walrand, S., Jourdan, M., Verlaan, S., & Luiking, Y. C. (2016) · Oncotarget · doi:10.18632/oncotarget.7800 · Cited by 31 · see citing works

Mitochondrial Adaptations in Aging Skeletal Muscle: Implications for Resistance Exercise Training to Treat Sarcopenia

Jeong, I., Cho, E., Yook, J.-S., Choi, Y., Park, D., Kang, J., Lee, S.-H., Seo, D. Y., Jung, S., & Kwak, H. (2024) · Life · doi:10.3390/life14080962 · Cited by 33 · see citing works

Proteomic strategies to unravel age-related redox signalling defects in skeletal muscle

Cobley, J. N., Sakellariou, G. K., Husi, H., & McDonagh, B. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.09.012 · Cited by 29 · see citing works

Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion

Mancini, A., Vitucci, D., Randers, M. B., Schmidt, J. F., Hagman, M., Andersen, T. R., Imperlini, E., Mandola, A., Orrù, S., Krustrup, P., et al. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00132 · Cited by 29 · see citing works

Perspective: Pragmatic Exercise Recommendations for Older Adults: The Case for Emphasizing Resistance Training

Tavoian, D., Russ, D. W., Consitt, L. A., & Clark, B. C. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00799 · Cited by 26 · see citing works

Modulation of mitochondrial phenotypes by endurance exercise contributes to neuroprotection against a MPTP-induced animal model of PD

Jang, Y., Kwon, I., Song, W., Cosío-Lima, L., Taylor, S. M., & Lee, Y. (2018) · Life Sciences · doi:10.1016/j.lfs.2018.08.045 · Cited by 28 · see citing works

Evaluation of intramyocellular and extramyocellular lipids in the paraspinal muscle in patients with chronic low back pain using MR spectroscopy: preliminary results

Takashima, H., Takebayashi, T., Ogon, I., Yoshimoto, M., Terashima, Y., Imamura, R., & Yamashita, T. (2016) · British Journal of Radiology · doi:10.1259/bjr.20160136 · Cited by 28 · see citing works

High‐intensity exercise training ameliorates aberrant expression of markers of mitochondrial turnover but not oxidative damage in skeletal muscle of men with essential hypertension

Fiorenza, M., Gunnarsson, T. P., Ehlers, T. S., & Bangsbo, J. (2018) · Acta Physiologica · doi:10.1111/apha.13208 · Cited by 27 · see citing works

Effect of mechanistic/mammalian target of rapamycin complex 1 on mitochondrial dynamics during skeletal muscle hypertrophy

Uemichi, K., Shirai, T., Hanakita, H., & Takemasa, T. (2021) · Physiological Reports · doi:10.14814/phy2.14789 · Cited by 27 · see citing works

Age-Associated declines in mitochondrial biogenesis and protein quality control factors are minimized by exercise training

Koltai, E., Hart, N., Taylor, A. W., Goto, S., Ngo, J. K., Davies, K. J. A., & Radak, Z. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00337.2011 · Cited by 152 · see citing works

Impact of Aging and Exercise on Mitochondrial Quality Control in Skeletal Muscle

Kim, Y., Triolo, M., & Hood, D. A. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/3165396 · Cited by 158 · see citing works

Exercise training and mitochondrial remodeling in aging skeletal muscle: A translational systematic review and meta-analysis

Yousaf, F., Kao, S., Ishaq, S., Shah, I. A., & Lee, S. (2026) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2026.106435

The Pleiotropic Effect of Physical Exercise on Mitochondrial Dynamics in Aging Skeletal Muscle

Barbieri, E., Agostini, D., Polidori, E., Potenza, L., Guescini, M., Lucertini, F., Annibalini, G., Stocchi, L., Santi, M. D., & Stocchi, V. (2016) · Apple Academic Press eBooks · doi:10.1201/b19985-11 · Cited by 3 · see citing works

Aerobic Exercise Training Induces the Mitonuclear Imbalance and UPRmt in the Skeletal Muscle of Aged Mice

Cordeiro, A. V., Brícola, R. S., Braga, R. R., Lenhare, L., Silva, V. R. R., Anaruma, C. P., Katashima, C. K., Crisol, B., Simabuco, F. M., da Silva, A. S. R., et al. (2020) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaa059 · Cited by 56 · see citing works