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'Protein Supplementation after Exercise and before Sleep Does Not Further Augment Muscle Mass and Strength Gains during Resistance Exercise Training in Active Older Men
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“and that protein supplementation after exercise and before sleep did not further increase skeletal muscle mass or strength gains during resistance training in active older men (Holwerda et al., 2018).”
From Protein intake by master swimmers: Implications for practice in Sports Nutrition—A cross-sectional study (2025) · cites this paper as Holwerda et al., 2018
In the citing paper
“similar benefits have not been observed in older adults [133].”
From Protein Requirements for Master Athletes: Just Older Versions of Their Younger Selves (2021) · cites this paper as [133]
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A Critical Evaluation of Simple Methods for the Estimation of Free Testosterone in Serum
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“Meta-analyses have shown that protein supplementation may further augment the skeletal muscle adaptive response to resistance exercise training (3, 4).”
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Predictors of skeletal muscle mass in elderly men and women
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“The age-related decline in skeletal muscle mass and strength, termed sarcopenia, is accompanied by impairments in functional capacity and an increased risk of developing chronic metabolic diseases (1, 2).”
BackgroundBauer, J. M., Verlaan, S., Bautmans, I., Brandt, K., Donini, L. M., Maggio, M., McMurdo, M. E. T., Mets, T., Seal, C., Wijers, S. L., et al. (2015) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2015.05.021 · Cited by 670 · cited 1×
“supplementation may be of greater benefit in more clinically compromised older populations when gains in muscle mass, strength, or both are restricted by habitual protein consumption (61).”
BackgroundTieland, M., Dirks, M. L., van der Zwaluw, N., Verdijk, L. B., van de Rest, O., de Groot, L. C. P. G. M., & van Loon, L. J. C. (2012) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2012.05.020 · Cited by 556 · cited 1×
“In contrast, protein supplementation has been reported to increase muscle mass and strength gains during resistance exercise training in prefrail older men and women who consume less than optimal amounts of dietary protein (5).”
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Satellite cell content is specifically reduced in type II skeletal muscle fibers in the elderly
Verdijk, L. B., Koopman, R., Schaart, G., Meijer, K., Savelberg, H. H. C. M., & van Loon, L. J. C. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00278.2006 · Cited by 489
Self-citationYang, Y., Breen, L., Burd, N. A., Hector, A. J., Churchward-Venne, T. A., Josse, A. R., Tarnopolsky, M. A., & Phillips, S. M. (2012) · British Journal of Nutrition · doi:10.1017/s0007114511007422 · Cited by 480
Dietary protein distribution positively influences 24-h muscle protein synthesis in healthy adults
Mamerow, M. M., Mettler, J. A., English, K. L., Casperson, S. L., Arentson-Lantz, E., Sheffield-Moore, M., Layman, D. K., & Paddon-Jones, D. (2014) · The Journal of Nutrition · doi:10.3945/jn.113.185280 · Cited by 438
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Self-citationStimulation of net muscle protein synthesis by whey protein ingestion before and after exercise
Tipton, K. D., Elliott, T. A., Cree, M. G., Aarsland, A. A., Sanford, A. P., & Wolfe, R. R. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00166.2006 · Cited by 307
Yang, Y., Churchward-Venne, T. A., Burd, N. A., Breen, L., Tarnopolsky, M. A., & Phillips, S. M. (2012) · Nutrition & Metabolism · doi:10.1186/1743-7075-9-57 · Cited by 286
Protein Ingestion before Sleep Improves Postexercise Overnight Recovery
RES, P. T., GROEN, B., PENNINGS, B., BEELEN, M., WALLIS, G. A., GIJSEN, A. P., SENDEN, J. M. G., & VAN LOON, L. J. C. (2012) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e31824cc363 · Cited by 226
Self-citationPaddon-Jones, D., Sheffield-Moore, M., Katsanos, C. S., Zhang, X.-J., & Wolfe, R. R. (2006) · Experimental Gerontology · doi:10.1016/j.exger.2005.10.006 · Cited by 223
Gorissen, S. H., Horstman, A. M., Franssen, R., Crombag, J. J., Langer, H., Bierau, J., Respondek, F., & van Loon, L. J. (2016) · The Journal of Nutrition · doi:10.3945/jn.116.231340 · Cited by 221
Leucine co-ingestion improves post-prandial muscle protein accretion in elderly men
Wall, B. T., Hamer, H. M., de Lange, A., Kiskini, A., Groen, B. B. L., Senden, J. M. G., Gijsen, A. P., Verdijk, L. B., & van Loon, L. J. C. (2013) · Clinical Nutrition · doi:10.1016/j.clnu.2012.09.002 · Cited by 220
Self-citationSnijders, T., Res, P. T., Smeets, J. S., van Vliet, S., van Kranenburg, J., Maase, K., Kies, A. K., Verdijk, L. B., & van Loon, L. J. (2015) · The Journal of Nutrition · doi:10.3945/jn.114.208371 · Cited by 175
Self-citationBukhari, S. S. I., Phillips, B. E., Wilkinson, D. J., Limb, M. C., Rankin, D., Mitchell, W. K., Kobayashi, H., Greenhaff, P. L., Smith, K., & Atherton, P. J. (2015) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00481.2014 · Cited by 162
Protein supplementation before and after resistance training in older men
Candow, D. G., Chilibeck, P. D., Facci, M., Abeysekara, S., & Zello, G. A. (2006) · European Journal of Applied Physiology · doi:10.1007/s00421-006-0223-8 · Cited by 158
Kukuljan, S., Nowson, C. A., Sanders, K., & Daly, R. M. (2009) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00392.2009 · Cited by 154
Murphy, C. H., Saddler, N. I., Devries, M. C., McGlory, C., Baker, S. K., & Phillips, S. M. (2016) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.116.136424 · Cited by 133
Trommelen, J., Kouw, I. W. K., Holwerda, A. M., Snijders, T., Halson, S. L., Rollo, I., Verdijk, L. B., & van Loon, L. J. C. (2018) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00273.2016 · Cited by 76
Self-citationResistance Exercise Augments Postprandial Overnight Muscle Protein Synthesis Rates
TROMMELEN, J., HOLWERDA, A. M., KOUW, I. W. K., LANGER, H., HALSON, S. L., ROLLO, I., VERDIJK, L. B., & VAN LOON, L. J. C. (2016) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001045 · Cited by 69
Self-citationImpact of protein coingestion on muscle protein synthesis during continuous endurance type exercise
Beelen, M., Zorenc, A., Pennings, B., Senden, J. M., Kuipers, H., & van Loon, L. J. C. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00446.2010 · Cited by 54
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Cited by
Kirk, B., Mooney, K., Amirabdollahian, F., & Khaiyat, O. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00445 · Cited by 72
Snijders, T., Trommelen, J., Kouw, I. W. K., Holwerda, A. M., Verdijk, L. B., & van Loon, L. J. C. (2019) · Frontiers in Nutrition · doi:10.3389/fnut.2019.00017 · Cited by 67
Self-citationMurphy, C., & Koehler, K. (2022) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/sms.14075 · Cited by 63
Straight, C. R., Fedewa, M. V., Toth, M. J., & Miller, M. S. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00170.2020 · Cited by 46
Liao, C.-D., Huang, S.-W., Chen, H.-C., Huang, M.-H., Liou, T.-H., & Lin, C.-L. (2024) · Nutrients · doi:10.3390/nu16070941 · Cited by 45
Metadata
- Authors
- Holwerda, A. M., Overkamp, M., Paulussen, K. J. M., Smeets, J. S. J., van Kranenburg, J., Backx, E. M. P., Gijsen, A. P., Goessens, J. P. B., Verdijk, L. B., & van Loon, L. J. C.
- Venue
- The Journal of Nutrition
- Publisher
- Elsevier BV
- Published
- 2018-11
- Volume
- 148
- Issue
- 11
- Pages
- 1723-1732
- ISSN
- 0022-3166
- Cited by
- 59
- References
- 28
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 1542 d)
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