A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells
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Frieder Schwenk, Udo Baron, Klaus Rajewsky; A cre -transgenic mouse strain for the ubiquitous deletion of loxP -flanked gene segments including deletion in germ
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Microglia play a vital role during typical development in shaping neuronal circuitry by pruning synapses.
“Microglia are known to play a vital role during typical development in shaping neuronal circuitry by pruning synapses2,11,12.”
From Constitutive expression of CX3CR1-BAC-Cre introduces minimal off-target effects in microglia (2026) · cites this paper as [11]
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- Authors
- Schwenk, F., Baron, U., & Rajewsky, K.
- Affiliations
- University of Cologne (DE)
- Heidelberg University (DE)
- Corresponding author
- Schwenk, Frieder
- Venue
- Nucleic Acids Research
- Publisher
- Oxford University Press (OUP)
- Published
- 1995
- Volume
- 23
- Issue
- 24
- Pages
- 5080-5081
- ISSN
- 0305-1048 (ISSN-L)
- 1362-4962
- PMC
- PMC307516
- OpenAlex
- W1968963646
- Cited by
- 1,289
- References
- 1
- Citations by year
- 2026: 31 · 2025: 35 · 2024: 52 · 2023: 51 · 2022: 55 · 2021: 48 · 2020: 50 · 2019: 58 · 2018: 52 · 2017: 39 · 2016: 45 · 2015: 57 · 2014: 62 · 2013: 55 · 2012: 54
- FWCI
- 7.09
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Nucleic Acids Research (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Animal Genetics and Reproduction
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › CRISPR and Genetic Engineering
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- conditional gene deletion, germ cells, germline deletion, Cre-loxP system
- MeSH terms
- Animals, DNA Nucleotidyltransferases, Germ Cells, Mice, Transgenic, Recombination, Genetic, Viral Proteins, Gene Deletion, Integrases, Mice
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