APACHE II-A Severity of Disease Classification System: Reply

Greater protein and energy intake may be associated with improved mortality in higher risk critically ill patients: a multicenter, multinational observational study

Compher, C., Chittams, J., Sammarco, T., Nicolo, M., & Heyland, D. K. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002083 · Cited by 264

Candidemia in non-neutropenic critically ill patients: analysis of prognostic factors and assessment of systemic antifungal therapy

Nolla-Salas, J., Sitges-Serra, A., León-Gil, C., Martínez-González, J., León-Regidor, M. A., Ibán˜ez-Lucí, P., & Torres-Rodríguez, J. M. (1997) · Intensive Care Medicine · doi:10.1007/s001340050286 · Cited by 263

Novel insights into the neuroendocrinology of critical illness

Van den Berghe, G. (2000) · European Journal of Endocrinology · doi:10.1530/eje.0.1430001 · Cited by 257

Intravascular Catheter Exchange and Duration of Candidemia

Rex, J. H., Bennett, J. E., Sugar, A. M., Pappas, P. G., Serody, J., Edwards, J. E., Washburn, R. G., NIAID Mycoses Study Group, & Candidemia Study Group (1995) · Clinical Infectious Diseases · doi:10.1093/clinids/21.4.994 · Cited by 252

Protein Requirements in the Critically Ill: A Randomized Controlled Trial Using Parenteral Nutrition

Ferrie, S., Allman‐Farinelli, M., Daley, M., & Smith, K. (2016) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607115618449 · Cited by 250

Prediction of outcome in critically ill patients using artificial neural network synthesised by genetic algorithm.

Dybowski, R., Gant, V, Weller, P., & Chang, R. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90609-1 · Cited by 240

Parenteral Nutrition with Fish Oil Modulates Cytokine Response in Patients with Sepsis

Mayer, K., Gokorsch, S., Fegbeutel, C., Hattar, K., Rosseau, S., Walmrath, D., Seeger, W., & Grimminger, F. (2003) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200207-674oc · Cited by 239

Comparison of Posthospitalization Function and Community Mobility in Hospital Mobility Program and Usual Care Patients: A Randomized Clinical Trial

Brown, C. J., Foley, K. T., Lowman, J. D., MacLennan, P. A., Razjouyan, J., Najafi, B., Locher, J., & Allman, R. M. (2016) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2016.1870 · Cited by 237

Implementation of guidelines for management of possible multidrug-resistant pneumonia in intensive care: An observational, multicentre cohort study.

Kett, D. H., Cano, E., Quartin, A. A., Mangino, J. E., Zervos, M. J., Peyrani, P., Cely, C. M., Ford, K. D., Scerpella, E. G., & Ramirez, J. A. (2011) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(10)70314-5 · Cited by 235

Hypoglycemia is associated with intensive care unit mortality*

Hermanides, J., Bosman, R. J., Vriesendorp, T. M., Dotsch, R., Rosendaal, F. R., Zandstra, D. F., Hoekstra, J. B. L., & DeVries, J. H. (2010) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181de562c · Cited by 236

Effects of nosocomial candidemia on outcomes of critically ill patients

Blot, S. I., Vandewoude, K. H., Hoste, E. A., & Colardyn, F. A. (2002) · The American Journal of Medicine · doi:10.1016/s0002-9343(02)01248-2 · Cited by 235

Intravenous amino acid therapy for kidney function in critically ill patients: a randomized controlled trial

Doig, G. S., Simpson, F., Bellomo, R., Heighes, P. T., Sweetman, E. A., Chesher, D., Pollock, C., Davies, A., Botha, J., Harrigan, P., et al. (2015) · Intensive Care Medicine · doi:10.1007/s00134-015-3827-9 · Cited by 232

Diagnostic accuracy of procalcitonin, neutrophil-lymphocyte count ratio, C-reactive protein, and lactate in patients with suspected bacterial sepsis

Ljungström, L., Pernestig, A.-K., Jacobsson, G., Andersson, R., Usener, B., & Tilevik, D. (2017) · PLOS ONE · doi:10.1371/journal.pone.0181704 · Cited by 219

Vancomycin dosing in critically ill patients: Robust methods for improved continuous-infusion regimens.

Roberts, J. A., Taccone, F. S., Udy, A. A., Vincent, J.-L., Jacobs, F., & Lipman, J. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01708-10 · Cited by 226

Methods of Blood Pressure Measurement in the ICU*

Lehman, L.-W. H., Saeed, M., Talmor, D., Mark, R., & Malhotra, A. (2013) · Critical Care Medicine · doi:10.1097/ccm.0b013e318265ea46 · Cited by 224

Critically Ill Children During the 2009–2010 Influenza Pandemic in the United States

Randolph, A. G., Vaughn, F., Sullivan, R., Rubinson, L., Thompson, B. T., Yoon, G., Smoot, E., Rice, T. W., Loftis, L. L., Helfaer, M., et al. (2011) · Pediatrics · doi:10.1542/peds.2011-0774 · Cited by 222

The impact of delirium on clinical outcomes in mechanically ventilated surgical and trauma patients

Lat, I., McMillian, W., Taylor, S., Janzen, J. M., Papadopoulos, S., Korth, L., Ehtisham, A., Nold, J., Agarwal, S., Azocar, R., et al. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e31819ffe38 · Cited by 222

Prediction of outcome in intensive care patients using endocrine parameters

Rothwell, P. M., & Lawler, P. G. (1995) · Critical Care Medicine · doi:10.1097/00003246-199501000-00015 · Cited by 219

COMPARISON OF PROPOFOL AND MIDAZOLAM FOR SEDATION IN CRITICALLY ILL PATIENTS

Aitkenhead, A., Willatts, S., Park, G., Collins, C., Ledingham, I., Pepperman, M., David Coates, P., Bodenham, A., Smith, M., & Wallace, P. M. (1989) · The Lancet · doi:10.1016/s0140-6736(89)90770-8 · Cited by 213

Early hospital mortality prediction of intensive care unit patients using an ensemble learning approach

Awad, A., Bader-El-Den, M., McNicholas, J., & Briggs, J. (2017) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2017.10.002 · Cited by 208

Intensive Nutrition in Acute Lung Injury: A Clinical Trial (INTACT)

Braunschweig, C. A., Sheean, P. M., Peterson, S. J., Gomez Perez, S., Freels, S., Lateef, O., Gurka, D., & Fantuzzi, G. (2015) · Journal of Parenteral and Enteral Nutrition · doi:10.1177/0148607114528541 · Cited by 199

APOε4 is associated with enhanced in vivo innate immune responses in human subjects

Gale, S. C., Gao, L., Mikacenic, C., Coyle, S. M., Rafaels, N., Murray Dudenkov, T., Madenspacher, J. H., Draper, D. W., Ge, W., Aloor, J. J., et al. (2014) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2014.01.032 · Cited by 202

Time from admission to initiation of surgery for source control is a critical determinant of survival in patients with gastrointestinal perforation with associated septic shock.

Azuhata, T., Kinoshita, K., Kawano, D., Komatsu, T., Sakurai, A., Chiba, Y., & Tanjho, K. (2014) · Critical Care · doi:10.1186/cc13854 · Cited by 206

Community-acquired respiratory coinfection in critically ill patients with pandemic 2009 influenza A(H1N1) virus

Martín-Loeches, I., Sanchez-Corral, A., Diaz, E., Granada, R. M., Zaragoza, R., Villavicencio, C., Albaya, A., Cerdá, E., Catalán, R. M., Luque, P., et al. (2011) · Chest · doi:10.1378/chest.10-1396 · Cited by 203

Heart rate variability as early marker of multiple organ dysfunction syndrome in septic patients

Pontet, J., Contreras, P., Curbelo, A., Medina, J., Noveri, S., Bentancourt, S., & Migliaro, E. R. (2003) · Journal of Critical Care · doi:10.1016/j.jcrc.2003.08.005 · Cited by 195

SARS–CoV-2–specific T cell responses and correlations with COVID-19 patient predisposition

Sattler, A., Angermair, S., Stockmann, H., Heim, K. M., Khadzhynov, D., Treskatsch, S., Halleck, F., Kreis, M. E., & Kotsch, K. (2020) · Journal of Clinical Investigation · doi:10.1172/jci140965 · Cited by 196

The clinical importance of a cytokine network in the acute phase of sepsis

Matsumoto, H., Ogura, H., Shimizu, K., Ikeda, M., Hirose, T., Matsuura, H., Kang, S., Takahashi, K., Tanaka, T., & Shimazu, T. (2018) · Scientific Reports · doi:10.1038/s41598-018-32275-8 · Cited by 193

Epidemiology of invasive mycosis in ICU patients: a prospective multicenter study in 435 non-neutropenic patients

Petri, M. G., König, J., Moecke, H. P., Gramm, H. J., Barkow, H., Kujath, P., Dennhart, R., Schäfer, H., Meyer, N., Kalmar, P., et al. (1997) · Intensive Care Medicine · doi:10.1007/s001340050334 · Cited by 185

The Association Between Nutritional Adequacy and Long-Term Outcomes in Critically Ill Patients Requiring Prolonged Mechanical Ventilation: A Multicenter Cohort Study*

Wei, X., Day, A. G., Ouellette-Kuntz, H., & Heyland, D. K. (2015) · Critical Care Medicine · doi:10.1097/ccm.0000000000001000 · Cited by 187

A prospective randomised trial of probiotics in critically ill patients

MCNAUGHT, C., WOODCOCK, N., ANDERSON, A., & MACFIE, J. (2005) · Clinical Nutrition · doi:10.1016/j.clnu.2004.08.008 · Cited by 179

Early enteral supplementation with key pharmaconutrients improves Sequential Organ Failure Assessment score in critically ill patients with sepsis: Outcome of a randomized, controlled, double-blind trial*

Beale, R. J., Sherry, T., Lei, K., Campbell-Stephen, L., McCook, J., Smith, J., Venetz, W., Alteheld, B., Stehle, P., & Schneider, H. (2008) · Critical Care Medicine · doi:10.1097/01.ccm.0000297954.45251.a9 · Cited by 182

Treatment-related risk factors for hospital mortality in Candida bloodstream infections

Labelle, A. J., Micek, S. T., Roubinian, N., & Kollef, M. H. (2008) · Critical Care Medicine · doi:10.1097/ccm.0b013e31818b3477 · Cited by 181

Prone Positioning and Low-Volume Pressure-Limited Ventilation Improve Survival in Patients With Severe ARDS

Stocker, R., Neff, T., Stein, S., Trentz, O., Ecknauer, E., & Russi, E. (1997) · Chest · doi:10.1378/chest.111.4.1008 · Cited by 178

Using machine learning methods to predict in-hospital mortality of sepsis patients in the ICU

Kong, G., Lin, K., & Hu, Y. (2020) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-020-01271-2 · Cited by 180

Capillary refill time during fluid resuscitation in patients with sepsis-related hyperlactatemia at the emergency department is related to mortality.

Lara, B., Enberg, L., Ortega, M., Leon, P., Kripper, C., Aguilera, P., Kattan, E., Castro, R., Bakker, J., & Hernandez, G. (2017) · PLOS ONE · doi:10.1371/journal.pone.0188548 · Cited by 167

A phase II randomized placebo-controlled trial of omega-3 fatty acids for the treatment of acute lung injury*

Stapleton, R. D., Martin, T. R., Weiss, N. S., Crowley, J. J., Gundel, S. J., Nathens, A. B., Akhtar, S. R., Ruzinski, J. T., Caldwell, E., Curtis, J. R., et al. (2011) · Critical Care Medicine · doi:10.1097/ccm.0b013e318218669d · Cited by 173

Early palliative care consultation in the medical ICU: A cluster randomized crossover trial.

Ma, J., Chi, S., Buettner, B., Pollard, K., Muir, M., Kolekar, C., Al-Hammadi, N., Chen, L., Kollef, M., & Dans, M. (2019) · Critical Care Medicine · doi:10.1097/ccm.0000000000004016 · Cited by 166

A multicenter, randomized controlled trial comparing early nasojejunal with nasogastric nutrition in critical illness*

Davies, A. R., Morrison, S. S., Bailey, M. J., Bellomo, R., Cooper, D. J., Doig, G. S., Finfer, S. R., & Heyland, D. K. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e318255d87e · Cited by 168

Implementation of a real-time computerized sepsis alert in nonintensive care unit patients*

Sawyer, A. M., Deal, E. N., Labelle, A. J., Witt, C., Thiel, S. W., Heard, K., Reichley, R. M., Micek, S. T., & Kollef, M. H. (2011) · Critical Care Medicine · doi:10.1097/ccm.0b013e318205df85 · Cited by 169

Predictive Factors of Mortality Due to Polymicrobial Peritonitis With Candida Isolation in Peritoneal Fluid in Critically Ill Patients

Dupont, H. (2002) · Archives of Surgery · doi:10.1001/archsurg.137.12.1341 · Cited by 163

Tight blood-glucose control without early parenteral nutrition in the ICU

Gunst, J., Debaveye, Y., Güiza, F., Dubois, J., De Bruyn, A., Dauwe, D., De Troy, E., Casaer, M. P., De Vlieger, G., Haghedooren, R., et al. (2023) · New England Journal of Medicine · doi:10.1056/nejmoa2304855 · Cited by 163

Timing of vasopressor initiation and mortality in septic shock: a cohort study

Beck, V., Chateau, D., Bryson, G. L., Pisipati, A., Zanotti, S., Parrillo, J. E., Kumar, A., & The Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group (2014) · Critical Care · doi:10.1186/cc13868 · Cited by 161

Accuracy of oscillometric blood pressure measurement according to the relation between cuff size and upper-arm circumference in critically ill patients

Bur, A., Hirschl, M. M., Herkner, H., Oschatz, E., Kofler, J., Woisetschläger, C., & Laggner, A. N. (2000) · Critical Care Medicine · doi:10.1097/00003246-200002000-00014 · Cited by 154

Severe sepsis cohorts derived from claims-based strategies appear to be biased toward a more severely ill patient population.

Whittaker, S.-A., Mikkelsen, M. E., Gaieski, D. F., Koshy, S., Kean, C., & Fuchs, B. D. (2013) · Critical Care Medicine · doi:10.1097/ccm.0b013e31827466f1 · Cited by 156

Frequency and outcome of patients with nonthyroidal illness syndrome in a medical intensive care unit

Plikat, K., Langgartner, J., Buettner, R., Bollheimer, L. C., Woenckhaus, U., Schölmerich, J., & Wrede, C. E. (2007) · Metabolism · doi:10.1016/j.metabol.2006.09.020 · Cited by 156

Factors associated with mortality of myxedema coma: report of eight cases and literature survey

YAMAMOTO, T., FUKUYAMA, J., & FUJIYOSHI, A. (1999) · Thyroid · doi:10.1089/thy.1999.9.1167 · Cited by 151

Impact of caloric intake in critically ill patients with, and without, refeeding syndrome: A retrospective study

Olthof, L. E., Koekkoek, W. A. C. K., van Setten, C., Kars, J. C. N., van Blokland, D., & van Zanten, A. R. H. (2018) · Clinical Nutrition · doi:10.1016/j.clnu.2017.08.001 · Cited by 156

A prospective study of prolonged stay in the intensive care unit: predictors and impact on resource utilization

ARABI, Y. (2002) · International Journal for Quality in Health Care · doi:10.1093/intqhc/14.5.403 · Cited by 152

Risk factors and prognosis of catheter-related bloodstream infection in critically ill patients: A multicenter study.

Garnacho-Montero, J., Aldabó-Pallás, T., Palomar-Martínez, M., Vallés, J., Almirante, B., Garcés, R., Grill, F., Pujol, M., Arenas-Giménez, C., Mesalles, E., et al. (2008) · Intensive Care Medicine · doi:10.1007/s00134-008-1204-7 · Cited by 150

Continuous infusion of β-lactam antibiotics in severe infections: a review of its role

Roberts, J. A., Paratz, J., Paratz, E., Krueger, W. A., & Lipman, J. (2007) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2007.02.002 · Cited by 150

Severe agitation among ventilated medical intensive care unit patients: frequency, characteristics and outcomes

Woods, J. C., Mion, L. C., Connor, J. T., Viray, F., Jahan, L., Huber, C., McHugh, R., Gonzales, J. P., Stoller, J. K., & Arroliga, A. C. (2004) · Intensive Care Medicine · doi:10.1007/s00134-004-2193-9 · Cited by 142

Delirium as detected by the CAM-ICU predicts restraint use among mechanically ventilated medical patients*

Micek, S. T., Anand, N. J., Laible, B. R., Shannon, W. D., & Kollef, M. H. (2005) · Critical Care Medicine · doi:10.1097/01.ccm.0000164540.58515.bf · Cited by 141

Parenterally administered dipeptide alanyl-glutamine prevents worsening of insulin sensitivity in multiple-trauma patients

Bakalar, B., Duska, F., Pachl, J., Fric, M., Otahal, M., Pazout, J., & Andel, M. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000196829.30741.d4 · Cited by 136

Surviving critical illness: Acute respiratory distress syndrome as experienced by patients and their caregivers

Cox, C. E., Docherty, S. L., Brandon, D. H., Whaley, C., Attix, D. K., Clay, A. S., Dore, D. V., Hough, C. L., White, D. B., & Tulsky, J. A. (2009) · Critical Care Medicine · doi:10.1097/ccm.0b013e3181b6f64a · Cited by 136

Recurrent delirium over 12 months predicts dementia: results of the Delirium and Cognitive Impact in Dementia (DECIDE) study

Richardson, S. J., Davis, D. H. J., Stephan, B. C. M., Robinson, L., Brayne, C., Barnes, L. E., Taylor, J.-P., Parker, S. G., & Allan, L. M. (2021) · Age and Ageing · doi:10.1093/ageing/afaa244 · Cited by 125

The combined administration of GH‐releasing peptide‐2 (GHRP‐2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP‐2 alone

Van den Berghe, G., Baxter, R. C., Weekers, F., Wouters, P., Bowers, C. Y., Iranmanesh, A., Veldhuis, J. D., & Bouillon, R. (2002) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2002.01255.x · Cited by 134

The Chylomicronemia Syndrome Is Most Often Multifactorial: A Narrative Review of Causes and Treatment

Chait, A., & Eckel, R. H. (2019) · Annals of Internal Medicine · doi:10.7326/m19-0203 · Cited by 128

Patient length of stay and mortality prediction: A survey

Awad, A., Bader–El–Den, M., & McNicholas, J. (2017) · Health Services Management Research · doi:10.1177/0951484817696212 · Cited by 128

Predictors of Mortality in Older Patients following Medical Intensive Care: The Importance of Functional Status

Mayer‐Oakes, S. A., Oye, R. K., & Leake, B. (1991) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1991.tb04452.x · Cited by 123

Inappropriate medication prescriptions in elderly adults surviving an intensive care unit hospitalization.

Morandi, A., Vasilevskis, E., Pandharipande, P. P., Girard, T. D., Solberg, L. M., Neal, E. B., Koestner, T., Torres, R. E., Thompson, J. L., Shintani, A. K., et al. (2013) · Journal of the American Geriatrics Society · doi:10.1111/jgs.12329 · Cited by 126

Propofol infusion for sedation in intensive care

NEWMAN, L. H., McDONALD, J. C., WALLACE, P. G. M., & LEDINGHAM, I. M. (1987) · Anaesthesia · doi:10.1111/j.1365-2044.1987.tb05362.x · Cited by 122

Ventilator-derived carbon dioxide production to assess energy expenditure in critically ill patients: proof of concept

Stapel, S. N., de Grooth, H.-J. S., Alimohamad, H., Elbers, P. W. G., Girbes, A. R. J., Weijs, P. J. M., & Oudemans-van Straaten, H. M. (2015) · Critical Care · doi:10.1186/s13054-015-1087-2 · Cited by 118

Impact of timing of surgery on outcome of Vibrio vulnificus-related necrotizing fasciitis.

Chao, W.-N., Tsai, C.-F., Chang, H.-R., Chan, K.-S., Su, C.-H., Lee, Y.-T., Ueng, K.-C., Chen, C.-C., Chen, S.-C., & Lee, M.-C. (2013) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2012.08.008 · Cited by 117

Inadequate salivary flow and poor oral mucosal status in intubated intensive care unit patients.

Dennesen, P., van der Ven, A., Vlasveld, M., Lokker, L., Ramsay, G., Kessels, A., van den Keijbus, P., van Nieuw Amerongen, A., & Veerman, E. (2003) · Critical Care Medicine · doi:10.1097/01.ccm.0000053646.04085.29 · Cited by 115

Loss of Consciousness at Onset of Subarachnoid Hemorrhage as an Important Marker of Early Brain Injury

Suwatcharangkoon, S., Meyers, E., Falo, C., Schmidt, J. M., Agarwal, S., Claassen, J., & Mayer, S. A. (2016) · JAMA Neurology · doi:10.1001/jamaneurol.2015.3188 · Cited by 114

Development and evaluation of an automated machine learning algorithm for in-hospital mortality risk adjustment among critical care patients.

Delahanty, R. J., Kaufman, D., & Jones, S. S. (2018) · Critical Care Medicine · doi:10.1097/ccm.0000000000003011 · Cited by 105

Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia*

Agbaht, K., Diaz, E., Muñoz, E., Lisboa, T., Gomez, F., Depuydt, P. O., Blot, S. I., & Rello, J. (2007) · Critical Care Medicine · doi:10.1097/01.ccm.0000277042.31524.66 · Cited by 109

A lactate-targeted resuscitation strategy may be associated with higher mortality in patients with septic shock and normal capillary refill time: A post hoc analysis of the ANDROMEDA-SHOCK study

Kattan, E., Hernández, G., Ospina-Tascón, G., Valenzuela, E. D., Bakker, J., & Castro, R. (2020) · Annals of Intensive Care · doi:10.1186/s13613-020-00732-1 · Cited by 100

Large Retrospective Evaluation of the Effectiveness and Safety of Ceftaroline Fosamil Therapy

Casapao, A. M., Davis, S. L., Barr, V. O., Klinker, K. P., Goff, D. A., Barber, K. E., Kaye, K. S., Mynatt, R. P., Molloy, L. M., Pogue, J. M., et al. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.02371-13 · Cited by 108

Quality Of Care For Two Common Illnesses In Teaching And Nonteaching Hospitals: Teaching status appears to make a difference, when physicians and nurses assess hospitals' quality of care in four states.

Ayanian, J. Z., Weissman, J. S., Chasan-Taber, S., & Epstein, A. M. (1998) · Health Affairs · doi:10.1377/hlthaff.17.6.194 · Cited by 106

Using a machine learning approach to predict mortality in critically ill influenza patients: A cross-sectional retrospective multicentre study in Taiwan

Hu, C.-A., Chen, C.-M., Fang, Y.-C., Liang, S.-J., Wang, H.-C., Fang, W.-F., Sheu, C.-C., Perng, W.-C., Yang, K.-Y., Kao, K.-C., et al. (2020) · BMJ Open · doi:10.1136/bmjopen-2019-033898 · Cited by 106

Patient safety, resident well-being and continuity of care with different resident duty schedules in the intensive care unit: a randomized trial

Parshuram, C. S., Amaral, A. C. K. B., Ferguson, N. D., Baker, G. R., Etchells, E. E., Flintoft, V., Granton, J., Lingard, L., Kirpalani, H., Mehta, S., et al. (2015) · Canadian Medical Association Journal · doi:10.1503/cmaj.140752 · Cited by 104

Early prediction of acute kidney injury following ICU admission using a multivariate panel of physiological measurements

Zimmerman, L. P., Reyfman, P. A., Smith, A. D. R., Zeng, Z., Kho, A., Sanchez-Pinto, L. N., & Luo, Y. (2019) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-019-0733-z · Cited by 100

Antipsychotic prescribing patterns during and after critical illness: A prospective cohort study.

Tomichek, J. E., Stollings, J. L., Pandharipande, P. P., Chandrasekhar, R., Ely, E. W., & Girard, T. D. (2016) · Critical Care · doi:10.1186/s13054-016-1557-1 · Cited by 100

Mortality in Relation to Frailty in Patients Admitted to a Specialized Geriatric Intensive Care Unit

Zeng, A., Song, X., Dong, J., Mitnitski, A., Liu, J., Guo, Z., & Rockwood, K. (2015) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glv084 · Cited by 96

Effect of mode of hydrocortisone administration on glycemic control in patients with septic shock: a prospective randomized trial

Loisa, P., Parviainen, I., Tenhunen, J., Hovilehto, S., & Ruokonen, E. (2007) · Critical Care · doi:10.1186/cc5696 · Cited by 95

The impact of delayed biliary decompression and anti-microbial therapy in 260 patients with cholangitis-associated septic shock.

Karvellas, C. J., Abraldes, J. G., Zepeda‐Gomez, S., Moffat, D. C., Mirzanejad, Y., Vazquez‐Grande, G., Esfahani, E. K., Kumar, A., & the Cooperative Antimicrobial Therapy of Septic Shock (CATSS) Database Research Group (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13764 · Cited by 94

Long-term ozone exposure increases the risk of developing the acute respiratory distress syndrome

Ware, L. B., Zhao, Z., Koyama, T., May, A. K., Matthay, M. A., Lurmann, F. W., Balmes, J. R., & Calfee, C. S. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201507-1418oc · Cited by 94

Clinical and economic impact of procalcitonin to shorten antimicrobial therapy in septic patients with proven bacterial infection in an intensive care setting.

Deliberato, R. O., Marra, A. R., Sanches, P. R., Dalla Valle Martino, M., dos Santos Ferreira, C. E., Pasternak, J., Paes, A. T., Pinto, L. M., dos Santos, O. F. P., & Edmond, M. B. (2013) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2013.03.027 · Cited by 93

External validation of prognostic models for critically ill patients required substantial sample sizes

Peek, N., Arts, D. G. T., Bosman, R. J., van der Voort, P. H. J., & de Keizer, N. F. (2007) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2006.08.011 · Cited by 92

The effect of time to antifungal therapy on mortality in candidemia associated septic shock

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