Cited by 532Inflammatory Bowel DiseaseTryptophan and brain disordersOcular Diseases and Behçet’s Syndrome

The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.

Impact of Depressive Mood on Relapse in Patients With Inflammatory Bowel Disease: A Prospective 18-Month Follow-Up Study

Mittermaier, Christian, Dejaco, Clemens, Waldhoer, Thomas, Oefferlbauer-Ernst, Anna, Miehsler, Wolfgang, Beier, Markus, Tillinger, Wolfgang, Gangl, Alfred, Moser, Gabriele·2004·Psychosomatic Medicine

DOI 10.1097/01.psy.0000106907.24881.f2

Open this paper in CoChat — free account

Abstract

OBJECTIVE: There is evidence of an interaction between psychological factors and activity of inflammatory bowel disease (IBD). We examined the influence of depressive mood and associated anxiety on the course of IBD over a period of 18 months in a cohort of patients after an episode of active disease. METHODS: In this prospective, longitudinal, observational study, 60 patients (37 women and 23 men) with clinically inactive IBD (Crohn disease, n = 47, 78%; ulcerative colitis, n = 13, 22%) were enrolled after a flare of disease. Psychological status, health-related quality of life (HRQOL), and disease activity were evaluated at baseline and then every 3 months for a period of 18 months by means of clinical and biological parameters, the Beck Depression Inventory (BDI), the Spielberger State-Trait Anxiety Inventory, the Inflammatory Bowel Disease Questionnaire, the Perceived Stress Questionnaire, and the Rating Form of Inflammatory Bowel Disease Patients Concerns. RESULTS: At baseline, depression (BDI > or = 13 points) was found in 17 of 60 (28%) patients. Thirty-two patients (59%) experienced at least one relapse during the 18 months of follow-up. Regression analysis showed a significant correlation between BDI scores at baseline and the total number of relapses after 12 (p <.01) and 18 months (p <.01) of follow-up. Furthermore, depression scores at baseline correlated with the time until the first recurrence of the disease (p <.05). Anxiety and low HRQOL were also related with more frequent relapses during follow-up (p <.05 and p <.01, respectively). CONCLUSIONS: Psychological factors such as a depressive mood associated with anxiety and impaired HRQOL may exert a negative influence on the course of IBD. Therefore, assessment and management of psychological distress should be included in clinical treatment of patients with IBD.

Integrity signals

Registry

Crossref · 10.1097/01.psy.0000106907.24881.f2

Cites

44 of 44 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
Untitled work
(1970) · Cited by 24,983
Inflammatory Bowel Disease
Podolsky, D. K. (2002) · New England Journal of Medicine · doi:10.1056/nejmra020831 · Cited by 3,183
Development of a Crohn's Disease Activity Index
Best, W. R., Becktel, J. M., Singleton, J. W., & Kern, F. (1976) · Gastroenterology · doi:10.1016/s0016-5085(76)80163-1 · Cited by 3,152
Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study.
Best, W. R., Becktel, J. M., Singleton, J. W., & Kern, F. (1976) · PubMed · Cited by 3,147
Depression and 18-Month Prognosis After Myocardial Infarction
Frasure‐Smith, N., Lespérance, F., & Talajic, M. R. (1995) · Circulation · doi:10.1161/01.cir.91.4.999 · Cited by 1,546
Hepatogastroenterology
Liu, B., Ying, J., Luo, C., Xu, Q., Zhu, L., & Zhong, H. (2012) · Hepatogastroenterology · doi:10.5754/hge11893 · Cited by 1,338
The Immunology of Mucosal Models of Inflammation
Strober, W., Fuss, I. J., & Blumberg, R. S. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.100301.064816 · Cited by 1,317
A New Measure of Health Status for Clinical Trials in Inflammatory Bowel Disease
Guyatt, G., Mitchell, A., Irvine, E. J., Singer, J., Williams, N., Goodacre, R. L., & Tompkins, C. (1989) · Gastroenterology · doi:10.1016/s0016-5085(89)80080-0 · Cited by 1,289
Coated mesalazine (5-aminosalicylic acid) versus sulphasalazine in the treatment of active ulcerative colitis: a randomised trial.
Rachmilewitz, D. (1989) · BMJ · doi:10.1136/bmj.298.6666.82 · Cited by 1,038

Show all 44 references

Research works printed but not linked: 7

Kordy, 1992, Psychother Psychosom Med Psychol, 42, 141
Levenstein, 1994, Am J Gastroenterol, 89, 1219
Moser, 1993, Psychosom Med, 55, A131
McFarlane, 1988, J Rheumatol, 15, 926
Stange, 1997, Z Gastroenterol, 35, 541
Cleeland, 1999, Proc Am Soc Clin Oncol, 18, A2215
Stein, 1989, J Clin Psychiatry, 50, 35

Sorted by citations

Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders
Kelly, J. R., Kennedy, P. J., Cryan, J. F., Dinan, T. G., Clarke, G., & Hyland, N. P. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00392 · Cited by 1,110
The second European evidence-based Consensus on the diagnosis and management of Crohn's disease: Special situations
Assche, G. V., Dignass, A. U., Reinisch, W., van der Woude, C. J., Sturm, A., Vos, M. D., Guslandi, M., Oldenburg, B., Dotan, I., Marteau, P. R., et al. (2009) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2009.09.009 · Cited by 891
Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice
Bercik, P., Verdu, E. F., Foster, J. A., Macri, J., Potter, M., Huang, X., Malinowski, P., Jackson, W., Blennerhassett, P., Neufeld, K. A., et al. (2010) · Gastroenterology · doi:10.1053/j.gastro.2010.06.063 · Cited by 674
Brain–Gut Interactions in Inflammatory Bowel Disease
Bonaz, B. L., & Bernstein, C. N. (2013) · Gastroenterology · doi:10.1053/j.gastro.2012.10.003 · Cited by 667
Psychological stress in IBD: new insights into pathogenic and therapeutic implications
Mawdsley, J. E., & Rampton, D. S. (2005) · Gut · doi:10.1136/gut.2005.064261 · Cited by 622
Prevention of gut leakiness by a probiotic treatment leads to attenuated HPA response to an acute psychological stress in rats
Ait-Belgnaoui, A., Durand, H., Cartier, C., Chaumaz, G., Eutamene, H., Ferrier, L., Houdeau, E., Fioramonti, J., Bueno, L., & Theodorou, V. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.03.024 · Cited by 612
Depression and anxiety in inflammatory bowel disease: A review of comorbidity and management
Graff, L. A., Walker, J. R., & Bernstein, C. N. (2009) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20873 · Cited by 586
Controversies Revisited: A Systematic Review of the Comorbidity of Depression and Anxiety with Inflammatory Bowel Diseases
Mikocka-Walus, A., Knowles, S. R., Keefer, L., & Graff, L. (2016) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000620 · Cited by 567
European evidence-based Consensus on the diagnosis and management of ulcerative colitis: Definitions and diagnosis
Stange, E. F., Travis, S. P. L., Vermeire, S., Reinisch, W., Geboes, K., Barakauskienė, A., Feakins, R. M., Fléjou, J., Herfarth, H. H., Hommes, D. W., et al. (2008) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2007.11.001 · Cited by 559
A comprehensive review and update on Crohn's disease
Gajendran, M., Loganathan, P., Catinella, A. P., & Hashash, J. G. (2017) · Disease-a-Month · doi:10.1016/j.disamonth.2017.07.001 · Cited by 553
Neuropeptide, Y, peptide YY and pancreatic polypeptide in the gut-brain axis
Holzer, P., Reichmann, F., & Farzi, A. (2012) · Neuropeptides · doi:10.1016/j.npep.2012.08.005 · Cited by 501
Management of Paediatric Ulcerative Colitis, Part 1
Turner, D., Ruemmele, F. M., Orlanski‐Meyer, E., Griffiths, A. M., de Carpi, J. M., Bronský, J., Veres, G., Aloi, M., Strisciuglio, C., Braegger, C., et al. (2018) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0000000000002035 · Cited by 510
ACG clinical guideline: Preventive care in inflammatory bowel disease
Farraye, F. A., Melmed, G. Y., Lichtenstein, G. R., & Kane, S. V. (2017) · American Journal of Gastroenterology · doi:10.1038/ajg.2016.537 · Cited by 473
Second European evidence-based consensus on the diagnosis and management of ulcerative colitis Part 3: Special situations
Assche, G. V., Dignass, A. U., Bokemeyer, B., Danese, S., Gionchetti, P., Moser, G., Beaugerie, L., Gomollón, F., Häuser, W., Herrlinger, K. R., et al. (2012) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2012.09.005 · Cited by 473
The Manitoba IBD Cohort Study: A Population-Based Study of the Prevalence of Lifetime and 12-Month Anxiety and Mood Disorders
Walker, J. R., Ediger, J. P., Graff, L. A., Greenfeld, J. M., Clara, I., Lix, L., Rawsthorne, P., Miller, N., Rogala, L., McPhail, C. M., et al. (2008) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2008.01980.x · Cited by 437
European evidence based consensus on the diagnosis and management of Crohn's disease: special situations
Caprilli, R., Gassull, M. A., Escher, J. C., Moser, G., Munkholm, P., Forbes, A., Hommes, D. W., Lochs, H., Angelucci, E., Cocco, A., et al. (2006) · Gut · doi:10.1136/gut.2005.081950c · Cited by 428
Bi-directionality of brain–gut interactions in patients with inflammatory bowel disease
Gracie, D. J., Guthrie, E. A., Hamlin, P. J., & Ford, A. C. (2018) · Gastroenterology · doi:10.1053/j.gastro.2018.01.027 · Cited by 408
The mucosal immune system: master regulator of bidirectional gut-brain communications
Powell, N., Walker, M. M., & Talley, N. J. (2017) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2016.191 · Cited by 379
The influence of the brain–gut axis in inflammatory bowel disease and possible implications for treatment
Gracie, D. J., Hamlin, P. J., & Ford, A. C. (2019) · The Lancet. Gastroenterology & hepatology · doi:10.1016/s2468-1253(19)30089-5 · Cited by 362
Symptoms of depression and anxiety are independently associated with clinical recurrence of inflammatory bowel disease
Mikocka-Walus, A., Pittet, V., Rossel, J.-B., von Känel, R., Anderegg, C., Bauerfeind, P., Beglinger, C., Begré, S., Belli, D., Bengoa, J. M., et al. (2016) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2015.12.045 · Cited by 348
Depression and inflammatory bowel disease: findings from two nationally representative Canadian surveys.
Fuller-Thomson, E., & Sulman, J. (2006) · Inflammatory Bowel Diseases · doi:10.1097/00054725-200608000-00005 · Cited by 292
Increased burden of psychiatric disorders in inflammatory bowel disease
Bernstein, C. N., Hitchon, C. A., Walld, R., Bolton, J. M., Sareen, J., Walker, J. R., Graff, L. A., Patten, S. B., Singer, A., Lix, L. M., et al. (2019) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izy235 · Cited by 274
Clinical depression and regulation of the inflammatory response during acute stress
Miller, G. E., Rohleder, N., Stetler, C., & Kirschbaum, C. (2005) · Psychosomatic Medicine · doi:10.1097/01.psy.0000174172.82428.ce · Cited by 253
Predicting relapse in Crohn’s disease: a biopsychosocial model
Bitton, A., Dobkin, P. L., Edwardes, M. D., Sewitch, M. J., Meddings, J. B., Rawal, S., Cohen, A., Vermeire, S., Dufresne, L., Franchimont, D., et al. (2008) · Gut · doi:10.1136/gut.2007.134817 · Cited by 254
The impact of major depressive disorder on the short‐ and long‐term outcome of Crohn's disease treatment with infliximab
PERSOONS, P., VERMEIRE, S., DEMYTTENAERE, K., FISCHLER, B., VANDENBERGHE, J., VAN OUDENHOVE, L., PIERIK, M., HLAVATY, T., VAN ASSCHE, G., NOMAN, M., et al. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02535.x · Cited by 253
Psychological issues in inflammatory bowel disease: an overview
Sajadinejad, M. S., Asgari, K., Molavi, H., Kalantari, M., & Adibi, P. (2012) · Gastroenterology Research and Practice · doi:10.1155/2012/106502 · Cited by 242
Fatigue and health-related quality of life in inflammatory bowel disease: Results from a population-based study in the Netherlands: The IBD-South Limburg cohort
Romberg-Camps, M. J. L., Bol, Y., Dagnelie, P. C., Hesselink-van de Kruijs, M. A. M., Kester, A. D. M., Engels, L. G. J. B., van Deursen, C., Hameeteman, W. H. A., Pierik, M., Wolters, F., et al. (2010) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21285 · Cited by 240
European evidence-based Consensus on the management of ulcerative colitis: Special situations
Biancone, L., Michetti, P., Travis, S. P. L., Escher, J. C., Moser, G., Forbes, A., Hoffmann, J. C., Dignass, A. U., Gionchetti, P., Jantschek, G., et al. (2008) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2007.12.001 · Cited by 236
Depression increases the risk of inflammatory bowel disease, which may be mitigated by the use of antidepressants in the treatment of depression
Frolkis, A. D., Vallerand, I. A., Shaheen, A.-A., Lowerison, M. W., Swain, M. G., Barnabe, C., Patten, S. B., & Kaplan, G. G. (2019) · Gut · doi:10.1136/gutjnl-2018-317182 · Cited by 228
Mood disorders in inflammatory bowel disease: Relation to diagnosis, disease activity, perceived stress, and other factors
Goodhand, J. R., Wahed, M., Mawdsley, J. E., Farmer, A. D., Aziz, Q., & Rampton, D. S. (2012) · Inflammatory Bowel Diseases · doi:10.1002/ibd.22916 · Cited by 234
The Spectrum of Achalasia: Lessons From Studies of Pathophysiology and High-Resolution Manometry
Kahrilas, P. J., & Boeckxstaens, G. E. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.08.038 · Cited by 236
Expression of the TRPV1 receptor differs in quiescent inflammatory bowel disease with or without abdominal pain
Akbar, A., Yiangou, Y., Facer, P., Brydon, W. G., Walters, J. R. F., Anand, P., & Ghosh, S. K. (2010) · Gut · doi:10.1136/gut.2009.194449 · Cited by 219
Is Irritable Bowel Syndrome a Low-Grade Inflammatory Bowel Disease?
Berčík, P., Verdu, E. F., & Collins, S. M. (2005) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2005.02.007 · Cited by 207
Stress and the Brain-Gut Axis in Functional and Chronic-Inflammatory Gastrointestinal Diseases: A Transdisciplinary Challenge
Labanski, A., Langhorst, J., Engler, H., & Elsenbruch, S. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.104501 · Cited by 200
Psychological adjustment and autonomic disturbances in inflammatory bowel diseases and irritable bowel syndrome
Pellissier, S., Dantzer, C., Canini, F., Mathieu, N., & Bonaz, B. (2010) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.10.004 · Cited by 198
Comorbidity between depression and inflammatory bowel disease explained by immune-inflammatory, oxidative, and nitrosative stress; tryptophan catabolite; and gut–brain pathways
Martín-Subero, M., Anderson, G., Kanchanatawan, B., Berk, M., & Maes, M. H. J. (2015) · CNS Spectrums · doi:10.1017/s1092852915000449 · Cited by 200
Systematic review with meta‐analysis: the adverse effects of tobacco smoking on the natural history of Crohn's disease
To, N., Gracie, D. J., & Ford, A. C. (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13511 · Cited by 189
Psychological interventions for treatment of inflammatory bowel disease
Timmer, A., Preiss, J. C., Motschall, E., Rücker, G., Jantschek, G., & Moser, G. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006913.pub2 · Cited by 187
Psychosocial Issues in Pediatric Inflammatory Bowel Disease
Mackner, L. M., Greenley, R. N., Szigethy, E., Herzer, M., Deer, K., & Hommel, K. A. (2013) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/mpg.0b013e3182841263 · Cited by 189
Gut–brain actions underlying comorbid anxiety and depression associated with inflammatory bowel disease
Abautret-Daly, Á., Dempsey, E., Parra‐Blanco, A., Medina, C., & Harkin, A. (2017) · Acta Neuropsychiatrica · doi:10.1017/neu.2017.3 · Cited by 186
Mechanisms by which Stress Affects the Experimental and Clinical Inflammatory Bowel Disease (IBD): Role of Brain-Gut Axis
Brzozowski, B., Mazur-Biały, A., Pajdo, R., Kwiecień, S., Bilski, J., Zwolińska-Wcisło, M., Mach, T., & Brzozowski, T. (2016) · Current Neuropharmacology · doi:10.2174/1570159x14666160404124127 · Cited by 168
Controversies surrounding the comorbidity of depression and anxiety in inflammatory bowel disease patients: A literature review
Mikocka-Walus, A. A., Turnbull, D. A., Moulding, N. T., Wilson, I. G., Andrews, J. M., & Holtmann, G. J. (2007) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20062 · Cited by 178
Effects of Mind-Body Therapy on Quality of Life and Neuroendocrine and Cellular Immune Functions in Patients with Ulcerative Colitis
Elsenbruch, S., Langhorst, J., Popkirowa, K., Müller, T., Lüdtke, R., Franken, U., Paul, A. E., Spahn, G., Michalsen, A., Janssen, O. E., et al. (2005) · Psychotherapy and Psychosomatics · doi:10.1159/000086318 · Cited by 177
Depression is associated with more aggressive inflammatory bowel disease
Kochar, B., Barnes, E. L., Long, M. D., Cushing, K. C., Galanko, J., Martin, C. F., Raffals, L. E., & Sandler, R. S. (2018) · American Journal of Gastroenterology · doi:10.1038/ajg.2017.423 · Cited by 178
Aktualisierte Leitlinie zur Diagnostik und Therapie der Colitis ulcerosa 2011 – Ergebnisse einer Evidenzbasierten Konsensuskonferenz
Dignass, A. U., Preiß, J., Aust, D., Autschbach, F., Ballauff, A., Barretton, G., Bokemeyer, B., Fichtner‐Feigl, S., Hagel, S., Herrlinger, K. R., et al. (2011) · Zeitschrift für Gastroenterologie · doi:10.1055/s-0031-1281666 · Cited by 179
Stress triggers flare of inflammatory bowel disease in children and adults
Sun, Y., Li, L., Xie, R., Wang, B., Jiang, K., & Cao, H. (2019) · Frontiers in Pediatrics · doi:10.3389/fped.2019.00432 · Cited by 171
Influences and impact of anxiety and depression in the setting of inflammatory bowel disease
Navabi, S., Gorrepati, V. S., Yadav, S., Chintanaboina, J., Maher, S., Demuth, P., Stern, B., Stuart, A., Tinsley, A., Clarke, K., et al. (2018) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izy143 · Cited by 172
A Review of Inflammatory Bowel Disease: A Model of Microbial, Immune and Neuropsychological Integration
Tavakoli, P., Vollmer-Conna, U. S., Hadzi-Pavlovic, D., & Grimm, M. (2021) · Public health reviews · doi:10.3389/phrs.2021.1603990 · Cited by 173
The incidence and risk factors for developing depression after being diagnosed with inflammatory bowel disease: a cohort study
Panara, A. J., Yarur, A. J., Rieders, B., Proksell, S., Deshpande, A. R., Abreu, M. T., & Sussman, D. A. (2014) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12669 · Cited by 168
Phenotypic changes in colonocytes following acute stress or activation of mast cells in mice: implications for delayed epithelial barrier dysfunction
Demaude, J. (2006) · Gut · doi:10.1136/gut.2005.078675 · Cited by 167
Anxiety and depression in patients with inflammatory bowel disease
Häuser, W., Janke, K.-H., Klump, B., & Hinz, A. (2010) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21346 · Cited by 163
The homeostatic role of neuropeptide Yin immune function and its impact on mood and behaviour
Farzi, A., Reichmann, F., & Holzer, P. (2015) · Acta Physiologica · doi:10.1111/apha.12445 · Cited by 145
Vagus Nerve Stimulation at the Interface of Brain–Gut InteractionsPreprint
Bonaz, B. L., Sinniger, V., & Sonia Pellissier, A. (2018) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a034199 · Cited by 151
Etiology and Treatment of Pain and Psychosocial Issues in Patients With Inflammatory Bowel Diseases
Regueiro, M., Greer, J. B., & Szigethy, E. (2017) · Gastroenterology · doi:10.1053/j.gastro.2016.10.036 · Cited by 142
Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis
Sofia, M. A., Ciorba, M. A., Meckel, K. R., Lim, C. K., Guillemin, G. J., Weber, C. R., Bissonnette, M., & Pekow, J. R. (2018) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izy103 · Cited by 145
The Patient Simple Clinical Colitis Activity Index (P-SCCAI) can detect ulcerative colitis (UC) disease activity in remission: A comparison of the P-SCCAI with clinician-based SCCAI and biological markers
Evertsz, F. B., Nieuwkerk, P. T., Stokkers, P. C. F., Ponsioen, C. Y., Bockting, C., Sanderman, R., & Sprangers, M. A. G. (2012) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2012.11.007 · Cited by 140
Psychological treatment may reduce the need for healthcare in patients with Crohnʼs disease
Deter, H., Keller, W., von Wietersheim, J., Jantschek, G., Duchmann, R., & Zeitz, M. (2007) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20068 · Cited by 137
S3-Leitlinie „Diagnostik und Therapie des Morbus Crohn”
Hoffmann, J., Preiß, J., Autschbach, F., Buhr, H. J., Häuser, W., Herrlinger, K. R., Höhne, W., Koletzko, S., Krieglstein, C. F., Kruis, W., et al. (2008) · Zeitschrift für Gastroenterologie · doi:10.1055/s-2008-1027796 · Cited by 134
Do Inflammatory Bowel Disease patients with anxiety and depressive symptoms receive the care they need?
Bennebroek Evertsz', F., Thijssens, N. A. M., Stokkers, P. C. F., Grootenhuis, M. A., Bockting, C. L. H., Nieuwkerk, P. T., & Sprangers, M. A. G. (2012) · Journal of Crohn's and Colitis · doi:10.1016/j.crohns.2011.07.006 · Cited by 131
The functional-organic dichotomy: postinfectious irritable bowel syndrome and inflammatory bowel disease-irritable bowel syndrome.
Grover, M., Herfarth, H., & Drossman, D. (2009) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2008.08.032 · Cited by 131
Do Antidepressants Influence the Disease Course in Inflammatory Bowel Disease? A Retrospective Case-Matched Observational Study
Goodhand, J., Greig, F. I. S., Koodun, Y., McDermott, A., Wahed, M., Langmead, L., & Rampton, D. S. (2011) · Inflammatory Bowel Diseases · doi:10.1002/ibd.21846 · Cited by 130
Mindfulness-based therapy for inflammatory bowel disease patients with functional abdominal symptoms or high perceived stress levels
Berrill, J. W., Sadlier, M., Hood, K., & Green, J. T. (2014) · Journal of Crohn's and Colitis · doi:10.1016/j.crohns.2014.01.018 · Cited by 123
Psychiatric co‐morbidity is associated with increased risk of surgery in Crohn's disease
Ananthakrishnan, A. N., Gainer, V. S., Perez, R. G., Cai, T., Cheng, S. ‐., Savova, G., Chen, P., Szolovits, P., Xia, Z., De Jager, P. L., et al. (2013) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.12195 · Cited by 122
Evidence that Stress Contributes to Inflammatory Bowel Disease: Evaluation, Synthesis, and Future Directions
Maunder, R. (2005) · Inflammatory Bowel Diseases · doi:10.1097/01.mib.0000161919.42878.a0 · Cited by 125
Antidepressants and inflammatory bowel disease: a systematic review.
Mikocka‐Walus, A. A., Turnbull, D. A., Moulding, N., Wilson, I. G., Andrews, J. M., & Holtmann, G. (2006) · Clinical Practice and Epidemiology in Mental Health · doi:10.1186/1745-0179-2-24 · Cited by 120
Psychological Factors Are Associated with Changes in the Health-related Quality of Life in Inflammatory Bowel Disease
Iglesias–Rey, M., Acosta, M. B., Caamaño‐Isorna, F., Vázquez, I., Ferreiro, R., Lindkvist, B., González, A. L., & Domínguez‐Muñoz, J. E. (2013) · Inflammatory Bowel Diseases · doi:10.1097/01.mib.0000436955.78220.bc · Cited by 118
Quality of life for patients with exacerbation in inflammatory bowel disease and how they cope with disease activity
Larsson, K., Lööf, L., Rönnblom, A., & Nordin, K. (2008) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2007.10.007 · Cited by 115
The Brain-Gut Axis: Psychological Functioning and Inflammatory Bowel Diseases
Peppas, S., Pansieri, C., Piovani, D., Danese, S., Peyrin‐Biroulet, L., Tsantes, A. G., Brunetta, E., Tsantes, A. Ε., & Bonovas, S. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10030377 · Cited by 116
Systematic review: psychosocial factors associated with pain in inflammatory bowel disease
Sweeney, L., Moss‐Morris, R., Czuber‐Dochan, W., Meade, L., Chumbley, G., & Norton, C. (2018) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.14493 · Cited by 112
Chronic fatigue is associated with impaired health‐related quality of life in inflammatory bowel disease
Jelsness‐Jørgensen, L., Bernklev, T., Henriksen, M., Torp, R., & Moum, B. A. (2010) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2010.04498.x · Cited by 107
The Role of Psychological Stress in Inflammatory Bowel Disease: Quality Assessment of Methods of 18 Prospective Studies and Suggestions for Future Research
Cámara, R. J. A., Ziegler, R., Begré, S., Schoepfer, A. M., & von Känel, R. (2009) · Digestion · doi:10.1159/000226087 · Cited by 106
Psychological stress and depression: risk factors for IBD
Bernstein, C. N. (2016) · Digestive Diseases · doi:10.1159/000442929 · Cited by 107
Psychotherapy with chronic inflammatory bowel disease patients: A Review
von Wietersheim, J., & Kessler, H. (2006) · Inflammatory Bowel Diseases · doi:10.1097/01.mib.0000236925.87502.e0 · Cited by 103
The Efficacy and Methodological Challenges of Psychotherapy for Adults with Inflammatory Bowel Disease: A Review
Knowles, S. R., Monshat, K., & Castle, D. J. (2013) · Inflammatory Bowel Diseases · doi:10.1097/mib.0b013e318296ae5a · Cited by 102
Comorbidity in inflammatory bowel disease
López–Sanromán, A. (2011) · World Journal of Gastroenterology · doi:10.3748/wjg.v17.i22.2723 · Cited by 102
Psychiatric comorbidity in the treatment of patients with inflammatory bowel disease
Filipović, B. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i13.3552 · Cited by 99
Effects of a Comprehensive Lifestyle Modification Program on Quality-of-Life in Patients with Ulcerative Colitis: A Twelve-Month Follow-Up
Langhorst, J., Mueller, T., Luedtke, R., Franken, U., Paul, A., Michalsen, A., Schedlowski, M., Dobos, G. J., & Elsenbruch, S. (2007) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365520601101682 · Cited by 94
Gratitude uniquely predicts lower depression in chronic illness populations: A longitudinal study of inflammatory bowel disease and arthritis.
Sirois, F. M., & Wood, A. M. (2017) · Health Psychology · doi:10.1037/hea0000436 · Cited by 93
Burden of comorbid anxiety and depression in patients with inflammatory bowel disease: a systematic literature review
Dubinsky, M. C., Dotan, I., Rubin, D. T., Bernauer, M. J., Patel, D. A., Cheung, R. Y., Modesto, I., Latymer, M., & Keefer, L. (2021) · Expert Review of Gastroenterology & Hepatology · doi:10.1080/17474124.2021.1911644 · Cited by 92
Psychosomatic Medicine: The Scientific Foundation of the Biopsychosocial Model
Novack, D. H., Cameron, O. G., Epel, E. S., Ader, R., Waldstein, S. R., Levenstein, S., Antoni, M. H., & Wainer, A. (2007) · Academic Psychiatry · doi:10.1176/appi.ap.31.5.388 · Cited by 96
Fatigue management in patients with IBD: a randomised controlled trial
Vogelaar, L., Spijker, A. V., Timman, R., van Tilburg, A. J. P., Bac, D., Vogelaar, T., Kuipers, E. J., Busschbach, J. J. V., & van der Woude, C. J. (2013) · Gut · doi:10.1136/gutjnl-2013-305191 · Cited by 93
T helper 17 cells may drive neuroprogression in major depressive disorder: Proposal of an integrative model
Slyepchenko, A., Maes, M., Köhler, C. A., Anderson, G., Quevedo, J., Alves, G. S., Berk, M., Fernandes, B. S., & Carvalho, A. F. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.02.002 · Cited by 89
Strategies to improve quality of life in adolescents with inflammatory bowel disease
Karwowski, C., Keljo, D. J., & Szigethy, E. (2009) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20919 · Cited by 89
Depression and Anxiety Disorders in Patients With Inflammatory Bowel Disease
Hu, S., Chen, Y., Chen, Y., & Wang, C. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.714057 · Cited by 94
Mindfulness-based cognitive therapy for inflammatory bowel disease patients: findings from an exploratory pilot randomised controlled trial
Schoultz, M., Atherton, I., & Watson, A. J. M. (2015) · Trials · doi:10.1186/s13063-015-0909-5 · Cited by 92
Cognitive-behavioural therapy has no effect on disease activity but improves quality of life in subgroups of patients with inflammatory bowel disease: a pilot randomised controlled trial
Mikocka-Walus, A., Bampton, P., Hetzel, D., Hughes, P., Esterman, A., & Andrews, J. M. (2015) · BMC Gastroenterology · doi:10.1186/s12876-015-0278-2 · Cited by 86
“As IBD is a life-long condition [11] and there is the potential for a bidirectional interaction between psychological status and disease relapse [12], and the additional factor that life stresses and psychological status are not constant over time, we chose to examine the effect of CBT in a general cohort of IBD patie…”
Background
Considering the Bidirectional Pathways Between Depression and IBD: Recommendations for Comprehensive IBD Care.
(2017) · Europe PMC (PubMed Central) · Cited by 86
Short-Term Stress, but Not Mucosal Healing Nor Depression Was Predictive for the Risk of Relapse in Patients with Ulcerative Colitis: A Prospective 12-Month Follow-up Study
Langhorst, J., Hofstetter, A., Wolfe, F., & Häuser, W. (2013) · Inflammatory Bowel Diseases · doi:10.1097/mib.0b013e3182a192ba · Cited by 85
Impact of Drug Therapy and Surgery on Quality of Life in Crohnʼs Disease
Wright, E. K., & Kamm, M. A. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000271 · Cited by 83
Effectiveness of cognitive-behavioral therapy on quality of life, anxiety, and depressive symptoms among patients with inflammatory bowel disease: A multicenter randomized controlled trial
Bennebroek Evertsz', F., Sprangers, M. A. G., Sitnikova, K., Stokkers, P. C. F., Ponsioen, C. Y., Bartelsman, J. F. W. M., van Bodegraven, A. A., Fischer, S., Depla, A. C. T. M., Mallant, R. C., et al. (2017) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000227 · Cited by 84
Major depressive disorder as a neuro-immune disorder: Origin, mechanisms, and therapeutic opportunities
Réus, G. Z., Manosso, L. M., Quevedo, J., & Carvalho, A. F. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105425 · Cited by 91
Genomic and Clinical Effects Associated with a Relaxation Response Mind-Body Intervention in Patients with Irritable Bowel Syndrome and Inflammatory Bowel Disease
Kuo, B., Bhasin, M., Jacquart, J., Scult, M. A., Slipp, L. E., Riklin, E. I. K., Lepoutre, V., Comosa, N., Norton, B.-A., Dassatti, A., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0123861 · Cited by 85
Effects of guided imagery with relaxation training on anxiety and quality of life among patients with inflammatory bowel disease
Mizrahi, M. C., Reicher-Atir, R., Levy, S., Haramati, S., Wengrower, D., Israeli, E., & Goldin, E. (2012) · Psychology & Health · doi:10.1080/08870446.2012.691169 · Cited by 83
Pain Management in Patients with Inflammatory Bowel Disease
Srinath, A. I., Young, E. E., & Szigethy, E. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000170 · Cited by 85
Which patients with IBD need psychological interventions? A controlled study
Miehsler, W., Weichselberger, M., Öfferlbauer-Ernst, A., Dejaco, C., Reinisch, W., Vogelsang, H., Machold, K., Stamm, T., Gangl, A., & Moser, G. (2008) · Inflammatory Bowel Diseases · doi:10.1002/ibd.20462 · Cited by 82
A Controlled Study of a Group Mindfulness Intervention for Individuals Living With Inflammatory Bowel Disease
Neilson, K., Ftanou, M., Monshat, K., Salzberg, M., Bell, S., Kamm, M. A., Connell, W., Knowles, S. R., Sevar, K., Mancuso, S. G., et al. (2016) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000629 · Cited by 80
Patient-Reported Outcomes of Quality of Life, Functioning, and GI/Psychiatric Symptom Severity in Patients with Inflammatory Bowel Disease (IBD)
IsHak, W. W., Pan, D., Steiner, A. J., Feldman, E. J., Mann, A., Mirocha, J., Danovitch, I., & Melmed, G. (2017) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000001060 · Cited by 83
Disruption of the blood–brain barrier during TNBS colitis
Natah, S. S., Mouihate, A., Pittman, Q. J., & Sharkey, K. A. (2005) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2005.00654.x · Cited by 79
Psychological problems in gastroenterology outpatients: A South Australian experience. Psychological co-morbidity in IBD, IBS and hepatitis C
Mikocka-Walus, A. A., Turnbull, D. A., Andrews, J. M., Moulding, N. T., Wilson, I. G., Harley, H. A., Hetzel, D. J., & Holtmann, G. J. (2008) · Clinical Practice and Epidemiology in Mental Health · doi:10.1186/1745-0179-4-15 · Cited by 76
Systematic review with meta‐analysis: the effect of tobacco smoking on the natural history of ulcerative colitis
To, N., Ford, A. C., & Gracie, D. J. (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13663 · Cited by 77

Authors: Mittermaier, C., Dejaco, C., Waldhoer, T., Oefferlbauer-Ernst, A., Miehsler, W., Beier, M., Tillinger, W., Gangl, A., & Moser, G.
Affiliations: University of Vienna (AT)
Corresponding author: Dejaco, Clemens
ORCID: Mittermaier, Christian
Dejaco, Clemens
Waldhoer, Thomas
Moser, Gabriele
Venue: Psychosomatic Medicine
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2004-01
Volume: 66
Issue: 1
Pages: 79-84
ISSN: 0033-3174 (ISSN-L)
DOI: 10.1097/01.psy.0000106907.24881.f2
OpenAlex: W2047170682
Cited by: 532
References: 44
Citations by year: 2026: 4 · 2025: 11 · 2024: 19 · 2023: 15 · 2022: 28 · 2021: 30 · 2020: 18 · 2019: 27 · 2018: 38 · 2017: 34 · 2016: 35 · 2015: 36 · 2014: 26 · 2013: 28 · 2012: 31
FWCI: 10.50
Type: journal article
Language: en
Open access: closed
Locations: Psychosomatic Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Gastroenterology › Inflammatory Bowel Disease
Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
Keywords: inflammatory bowel disease, depressive mood, depression, anxiety, relapse, Crohn's disease, ulcerative colitis, health-related quality of life, psychological distress, disease activity
MeSH terms: Adult, Affect, Colitis, Ulcerative, Crohn Disease, Depression, Female, Follow-Up Studies, Humans, Male, Middle Aged, Prospective Studies, Psychological Tests, Quality of Life, Recurrence, Severity of Illness Index, Inflammatory Bowel Diseases, Disease Progression

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Impact of Depressive Mood on Relapse in Patients With Inflammatory Bowel Disease: A Prospective 18-Month Follow-Up Study

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks