The DOI matches its Crossref record; 80 of the 80 references it cites were found in a registry or an index; 1 of the 52 sources its claims cite were checked for support.
Sociability and preference for social novelty in five inbred strains: an approach to assess autistic‐like behavior in mice
Open accessAbstract
Deficits in social interaction are important early markers for autism and related neurodevelopmental disorders with strong genetic components. Standardized behavioral assays that measure the preference of mice for initiating social interactions with novel conspecifics would be of great value for mutant mouse models of autism. We developed a new procedure to assess sociability and the preference for social novelty in mice. To quantitate sociability, each mouse was scored on measures of exploration in a central habituated area, a side chamber containing an unfamiliar conspecific (stranger 1) in a wire cage, or an empty side chamber. In a secondary test, preference for social novelty was quantitated by presenting the test mouse with a choice between the first, now‐familiar, conspecific (stranger 1) in one side chamber, and a second unfamiliar mouse (stranger 2) in the other side chamber. Parameters scored included time spent in each chamber and number of entries into the chambers. Five inbred strains of mice were tested, C57BL/6J, DBA/2J, FVB/NJ, A/J and B6129PF2/J hybrids. Four strains showed significant levels of sociability (spend‐ ing more time in the chamber containing stranger 1 than in the empty chamber) and a preference for social novelty (spending more time in the chamber containing stranger 2 than in the chamber containing the now‐familiar stranger 1). These social preferences were observed in both male and female mice, and in juveniles and adults. The exception was A/J, a strain that demonstrated a preference for the central chamber. Results are discussed in terms of potential applications of the new methods, and the proper controls for the interpretation of social behavior data, including assays for health, relevant sensory abilities and motor functions. This new standardized procedure to quantitate sociability and preference for social novelty in mice provides a method to assess tendencies for social avoidance in mouse models of autism.
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63 Own result · 16 No full text of the sources · 15 Own method · 6 Not checked yet · 6 Own interpretation · 5 Sources not found · 2 No basis given · 1 Partly supported · accuracy not yet measured
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Four strains showed significant levels of sociability (spending more time in the chamber containing stranger 1 than in the empty chamber)”
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In the paper
“Four strains showed significant levels of sociability (spending more time in the chamber containing stranger 1 than in the empty chamber) and a preference for social novelty (spending more time in the chamber containing stranger 2 than in the chamber containing the now-familiar stranger 1).”
plain- Asserted: passes — The authors put it forward as true.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“These social preferences were observed in both male and female mice, and in juveniles and adults.”
plain- Asserted: passes — The authors put it forward as true.
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- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“These social preferences were observed in both male and female mice, and in juveniles and adults.”
plain- Asserted: passes — The authors put it forward as true.
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- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The exception was A/J, a strain that demonstrated a preference for the central chamber.”
boosted- Asserted: passes — The authors put it forward as true.
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- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
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A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Overall, four of the five inbred and hybrid strains tested spent more time in the side of the social test box containing the unfamiliar stranger, vs. time in the empty side.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Discussion
plain- Asserted: passes — The authors put it forward as true.
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In the paper
“DBA/2 mice tended to have lower numbers of entries than the C57BL/6J mice (Fig. 10b; significant main effect of strain, F 1,9 ¼ 16.156, P ¼ 0.003; retest, F 1,9 ¼ 36.215,P ¼ 0.0002; and side, F 1,9 ¼ 8.723, P ¼ 0.0161).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
hedgedcorrelational- Asserted: passes — The authors put it forward as true.
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In the paper
“Finally, the adult C57BL/6J and DBA/2 mice had higher numbers of entries into the side of the chamber containing the unfamiliar conspecific in the sociability test.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plainn = 2- Asserted: passes — The authors put it forward as true.
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In the paper
“Adult A/J males failed to show a significant preference for the side containing stranger 1, as compared to the empty side.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plain- Asserted: passes — The authors put it forward as true.
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In the paper
“The low number of entries observed in the A/J mice was significantly different from both of the other inbred strains (post hoc tests following repeated measures ANOVA, F-values above).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plain- Asserted: passes — The authors put it forward as true.
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- It may state two separate claims as one. 24
- The quote only partly states this claim. 1
- Probably not a substantial claim. 32
The cited sources support only part of this claim — read each source’s verdict below.
In the paper
“Higher numbers of sniffs were directed toward stranger 1 than towards the empty wire cage, and towards the novel stranger 2 vs. the now-familiar stranger 1, in C57BL/6J, DBA/2J and FVB/NJ male mice (Nadler et al. 2004).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
- Partly supportedcites Nadler et al. 2004 sourceExperimental — accuracy not yet measured
The “Social behavior tasks in three inbred strains” section reports that males of all three named strains spent more time sniffing the cage containing stranger 1 than the empty cage, and more time sniffing stranger 2 than stranger 1. The “Sociability test” section specifies that sniffing was scored as cumulative duration in seconds, not as a number of sniffs; that measurement in the claim is unsupported. Page numbers are unavailable in our copy. (LLM, conf=0.86)
plain- Asserted: passes — The authors put it forward as true.
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It may state two separate claims as one.
- Partly supported
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“General health, neurological reflexes, activity levels, motor functions and sensory abilities were normal in most regards for the strains tested.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
hedged- Asserted: passes — The authors put it forward as true.
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It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Similar levels of sociability were clearly evident in a group of young female C57BL/6J mice.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Discussion
boosted- Asserted: passes — The authors put it forward as true.
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- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
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The quote only partly states this claim.
The paper states this without a source or data behind it here, so there is nothing to check it against. The quote shows it is in the paper.
In the paper
“A/J was the only strain tested that failed to spend more time with a conspecific, and spent most of its time in the central chamber after the initial 5-minute habituation session.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Discussion
plain- Asserted: passes — The authors put it forward as true.
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It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“All of the inbred strains were able to locate buried food, supporting an interpretation that none were anosmic, which could have severely impacted social behaviors by blocking detection of olfactory cues emitted by the stranger mice.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“For the olfactory test, the majority of the subjects successfully located and retrieved the buried food.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > General health, home cage behavior, neurophysiological reflexes and sensory and motor function
plain- Asserted: passes — The authors put it forward as true.
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- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“As shown in Fig. 9, the A/J group did show significant increases in time spent in the side regions (Fig. 9a, significant main effect of retest, F 1,9 ¼ 11.343, P ¼ 0.0083) and in number of entries (Fig. 9b, significant main effect of retest, F 1,9 ¼ 13.302, P ¼ 0.0053) when the openings between chambers were more accessible.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Sociability procedure with modified social test box
plaindirect- Asserted: passes — The authors put it forward as true.
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- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“the significantly higher locomotor scores observed in the FVB/NJ strain, in comparison to the other two groups, were not reflected in an overall higher number of entries.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The FVB/NJ mice demonstrated a significantly shorter latency for locating the buried food,”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
boosted- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“A significant interaction was found between side of chamber and test condition (F 1,57 ¼ 67.634, P < 0.0001), reflecting the finding that preference was for the stranger 1 side during the first half of the session (the sociability condition), but switched to the stranger 2 side during the last part of the session (the social novelty condition).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Social behavior
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Arguing against an artifactual interpretation that hypolocomotion caused the social deficit in the A/J group are the data of Fig. 8. Repeated testing of A/J in the modified apparatus increased the number of entries, but did not yield significant sociability scores.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“The A/J mice spent significantly more time in the center chamber, indicating a strong preference for the start box that was not seen in the other strains.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
boostedcorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In the second group of juvenile C57BL/6J mice, both males and females made equal numbers of entries into each side of the social test box during the assay for sociability, but showed an increased number of entries into the side of the social box containing the second, 'novel' unfamiliar stranger during the test for social novelty.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“There were no significant differences between the strains in body weight or rotarod performance (see Table 1 for mean latency to fall on the second trial).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > General health, home cage behavior, neurophysiological reflexes and sensory and motor function
plain- Asserted: passes — The authors put it forward as true.
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- Load-bearing: passes — The paper’s conclusions depend on it.
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It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Therefore, for the juvenile male mice, number of entries did not reflect the trends for social preference seen in the duration measures, and only partially correlated with their locomotor activity independently quantitated in the open field.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In addition, low locomotor scores in DBA/2J and high locomotor scores in FVB/NJ appeared to be unrelated to amount of time spent in the chamber with stranger 1 and stranger 2.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
hedged- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“Significant preferences for sociability (Fig. 3a) or preference for social novelty (Fig. 3b) were not observed for number of chamber entries in any of the inbred strains.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Social behavior
plain- Asserted: passes — The authors put it forward as true.
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- Load-bearing: unclear — It is unclear whether the paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A result the paper reports from its own data — it cites no other source for it, so there is none to check. The quote shows it is in the paper.
In the paper
“In the present study, the juvenile male mice made nests and huddled together while sleeping.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plain- Asserted: passes — The authors put it forward as true.
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- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“Autistic individuals may further avoid unfamiliar social partners and display diminished interest in novelty (American Psychiatric Association 1994).”
What the sources say
- Not matchedcites American Psychiatric Association 1994
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
hedgedconditional- Asserted: passes — The authors put it forward as true.
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Probably not a substantial claim. It may state two separate claims as one.
- Not matched
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“This modification focuses the task on social approach tendencies, relevant to the social approach deficit in autism, while avoiding potential confounds resulting from aggressive or sexual interactions.”
plaindirect- Asserted: passes — The authors put it forward as true.
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It may state two separate claims as one.
- Rests on an assumption: Most autistic individuals demonstrate reduced or unusual social approach.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“To ensure that differences in social behaviors were not artifacts of other aspects of mouse behaviors, a series of independent control experiments was conducted to evaluate potential confounding factors.”
plain- Asserted: passes — The authors put it forward as true.
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Probably not a substantial claim.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The number of times that the mouse exited from the habituated empty central chamber into the novel empty chamber provided a general measure of locomotor function.”
plaincorrelational- Asserted: passes — The authors put it forward as true.
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- Load-bearing: fails — The paper’s conclusions may not depend on it.
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Probably not a substantial claim. The paper’s conclusions may not depend on it.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“Social behaviors have been explored in mice with mutations in candidate genes such as oxytocin (Winslow & Insel 2002;Young et al. 2002), monoamine oxidase-A (Shih & Chen 1999), fragile X (Churchill et al. 2002;Mineur et al. 2002) and dishevelled-1 (Lijam et al. 1997).”
What the sources say
plain- Asserted: passes — The authors put it forward as true.
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- Load-bearing: fails — The paper’s conclusions may not depend on it.
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Probably not a substantial claim. The paper’s conclusions may not depend on it.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“Further controls were designed to detect additional symptoms relevant to autism, such as abnormalities in locomotion or motor coordination (Hallett et al. 1993;Piven et al. 1997), that could directly affect performance of the social task.”
What the sources say
plain- Asserted: passes — The authors put it forward as true.
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Probably not a substantial claim.
In the paper
“Measures of general health, home cage behavior and neurological reflexes were conducted to rule out gross physical abnormalities (Crawley 2000).”
What the sources say
- Not checked — no full text of the sourcecites Crawley 2000
plain- Asserted: passes — The authors put it forward as true.
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- Load-bearing: passes — The paper’s conclusions depend on it.
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Probably not a substantial claim.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Retrieval of food buried in cage bedding was quantitated in a 15-minute olfactory test, to ensure that the subject mice were not grossly impaired in olfaction abilities.”
plain- Asserted: passes — The authors put it forward as true.
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Probably not a substantial claim.
None of the sources cited for this claim have been checked yet.
In the paper
“A large body of evidence from twin and family studies supports the important role of genetic factors in the etiology of autism (Bailey et al. 1995;Ritvo et al. 1989;Szatmari et al. 1998).”
What the sources say
boostedcorrelational- Asserted: passes — The authors put it forward as true.
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- Load-bearing: fails — The paper’s conclusions may not depend on it.
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Probably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The present mouse tasks were designed to maximize face validity to some of the core symptoms of autism.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. The paper may give no reason why it holds.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Therefore, the A/J mice were given a second test one week later, with the dividing walls between the chamber sides partially retracted to facilitate exploration.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Test for sociability in adult male mice
plainn = 10- Asserted: passes — The authors put it forward as true.
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- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
In the paper
“Given the primacy of social impairment in autism, we considered this symptom to be fundamental to a mouse model of autism (Insel 2001).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Discussion
What the sources say
- Not matchedcites Insel 2001
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
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Probably not a substantial claim.
- Not matched
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Several additional behavioral assays were performed in the initial set of juvenile male mice (C57BL/6J, DBA/2J and FVB/ NJ).These assays were designed as controls for sensory and motor abilities, etc., to ensure that the test mice were physically able to perform the procedures necessary for the social tasks described above.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The chambers of the social apparatus were cleaned and fresh paper chip bedding was added between trials.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Tests for sociability and social novelty preference
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The location of stranger 1 in the left vs. right side chamber was systematically alternated between trials.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Tests for sociability and social novelty preference
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“In our experience to date with the present procedures, human observers attain a high level of proficiency after only one or two practice sessions, with high rates (greater than 95%) of interrater reliability between trained observers.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The present protocol used a small wire cage to enclose the stimulus mouse, which allowed visual, auditory and olfactory contact between the mice, but prevented the occurrence of aggressive and other responses.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. It may state two separate claims as one.
In the paper
“From an early age, autistic children show low levels of eye contact and affective responses, less orientation toward others and language deficits, with a concomitant paucity of speech and social communication (for review, see Tager-Flusberg et al. 2001).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Discussion
What the sources say
- Not checked — no full text of the sourcecites Tager-Flusberg et al. 2001 source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The stranger mouse was enclosed in a small, round wire cage (Galaxy Cup, Spectrum Diversified Designs, Inc., Streetsboro, OH), which allowed nose contact between the bars, but prevented fighting.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Tests for sociability and social novelty preference
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“Previous work in social recognition has shown that mice show both habituation of olfactory responses directed toward an unfamiliar conspecific, and dishabituation, with a reinstatement of social sniffing, when a novel stimulus animal is presented (Bluthe et al. 1993;Dluzen & Kreutzberg 1993;Ferguson et al. 2000;Kogan et al. 2000;Winslow & Camacho 1995).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
It may state two separate claims as one.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“Alternatively, these data may reflect the low levels of open field exploratory behaviors and high levels of anxiety-like behaviors in the light/dark transitions test reported for A/J mice in other studies (Bouwknecht & Paylor 2002;Mathis et al. 1994Mathis et al. , 1995;;Thifault et al. 2002;Wahlsten et al. 2003) and reflected in the low number of entries in the present study.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“The present procedures for the sociability and social novelty tests are designed to be simple, quantitative and easily mastered by investigators.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
plain- Asserted: passes — The authors put it forward as true.
- Checkable: fails — It may be too vague to check against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: fails — The paper may give no reason why it holds.
Probably not a substantial claim. It may be too vague to check against evidence. The paper’s conclusions may not depend on it. The paper may give no reason why it holds. It may state two separate claims as one.
What the paper did — it cites no source for this, so there is none to check. The quote shows it is in the paper.
In the paper
“Therefore, the present methods were designed to quantitate levels of sociability, i.e. tendency to initiate social contact, and preference for social novelty, i.e. tendency to initiate social contacts with a new individual as compared to someone familiar from past experience, using a simple scoring approach for laboratory mice.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Discussion
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: passes — The paper’s conclusions depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“For example, some autistic patients demonstrate aberrant motor responses, including repeated hand flapping, jumping and other repetitive and stereotyped behaviors (Bodfish et al. 2000;Tager-Flusberg et al. 2001).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“Altered sensory responses have been reported, including both hypo-and hyper-reactivity to environmental stimuli (Baranek 2002).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
- Not checked — no full text of the sourcecites Baranek 2002 source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“Observational findings in some of these behavioral domains have been reported in some targeted gene mutations, e.g.deficits in social interaction within the home cage have been reported for mice deficient in the dishevelled-1 gene (Lijam et al. 1997) or the NMDA NR1 subunit (Mohn et al. 1999).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
plaindirect- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“Use of the three-chambered apparatus for demonstrating social preference (Insel 2001) was adapted by Brodkin et al. (2004) to investigate social approach and avoidance in female mice.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
- Not matchedcites Insel 2001
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not checked — no full text of the sourcecites Brodkin et al. 2004 source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
- Not matched
A claim is checked only against the cited paper’s full text, never its abstract, and none is available for its sources.
In the paper
“Observations of mice in these settings have shown that exposure to an unfamiliar stranger typically evokes a period of intense social sniffing, which may be followed by escalating aggressive responses or sexual behavior, dependent upon such factors as age and sex of the unfamiliar conspecific (Bluthe et al. 1993;Kogan et al. 2000;Winslow & Camacho 1995).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
hedgedconditional- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it. It may state two separate claims as one.
None of the sources cited for this claim have been checked yet.
In the paper
“and the mouse model of fragile X syndrome has been characterized by changes in activity (Bakker et al. 1994;Peier et al. 2000) and reactivity to acoustic stimuli (Chen & Toth 2001;Nielson et al. 2002).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
- Not matchedcites Bakker et al. 1994
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not matchedcites Peier et al. 2000
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Not checked — no full text of the sourcecites Chen & Toth 2001 source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
- Not matched
In the paper
“Children with fragile X syndrome often show autistic behavior (Hagerman et al. 1986),”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
- Not checked — no full text of the sourcecites Hagerman et al. 1986 source
plaincorrelational- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
In the paper
“As noted by Winslow (2003), the analysis of the full behavioral series that can occur in social tests demands familiarity with the mouse ethogram, extensive training and the ability to discern the sometimes rapid and fleeting responses that mice can emit.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
- Not checked — no full text of the sourcecites Winslow 2003 source
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
None of the sources cited for this claim have been checked yet.
In the paper
“Methods are based on procedures examining pair-bonding in voles (Dean, S.M. & Vandenbergh, J.G. as above), as well as many other elegant tests for social behavior in rodents (Bluthe et al. 1993;Carter et al. 1995;Dluzen & Kreutzberg 1993;Gheusi et al. 1994;Insel and Young 2001;Kogan et al. 2000;Winslow & Camacho 1995;Winslow 2003).”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Mouse sociability tasks
What the sources say
plain- Asserted: passes — The authors put it forward as true.
- Checkable: passes — It can be checked against evidence.
- Load-bearing: fails — The paper’s conclusions may not depend on it.
- Based: passes — The paper gives a reason why it holds.
Probably not a substantial claim. The paper’s conclusions may not depend on it.
The paper relies on this without support.
Most autistic individuals demonstrate reduced or unusual social approach.
“We reasoned that most autistic individuals demonstrate reduced or unusual social approach.”
The paper relies on this without support.
Behavioral models of autistic-like responses in mice have received little attention.
“However, to date, behavioral models of autistic-like responses in mice have received little attention.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Studies aimed at modeling, in animals, the core phenotypes associated with ASDs have focused on studying social and repetitive behaviors in mice [530-532] and pair-bonding behaviors in the prairie vole (Microtus ochrogaster) [533,534].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [530]
In the citing paper
“There is compelling evidence that some strains are more”
From Ecological validity of social interaction tests in rats and mice (2019) · cites this paper as [9]
In the citing paper
“However, almost all of them display some level of sociability (ie, preference to explore other mice over inanimate objects 9 ).”
From Ecological validity of social interaction tests in rats and mice (2019) · cites this paper as [9]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Rated minor: it would not touch a result — a value no result rests on, a p-value that stays on the same side of the significance level, or a conflict that is clerical, resolved elsewhere in the paper, or outside its own findings.
In the paper
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice
“These social preferences were observed in both male and female mice, and in juveniles and adults.”
§ Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice > Test for sociability in adult male mice
“the social novelty test was not conducted”
Citations
Cites
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Epidemiological Surveys of Autism and Other Pervasive Developmental Disorders: An Update
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Varieties of Repetitive Behavior in Autism: Comparisons to Mental Retardation
Bodfish, J. W., Symons, F. J., Parker, D. E., & Lewis, M. H. (2000) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1005596502855 · Cited by 1,223
The neurobiology of attachment
Insel, T. R., & Young, L. J. (2001) · Nature Reviews Neuroscience · doi:10.1038/35053579 · Cited by 1,173
A Comparison of the Social Postures of Some Common Laboratory Rodents
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Social amnesia in mice lacking the oxytocin gene
Ferguson, J. N., Young, L. J., Hearn, E. F., Matzuk, M. M., Insel, T. R., & Winslow, J. T. (2000) · Nature Genetics · doi:10.1038/77040 · Cited by 1,130
Fmr1 knockout mice: A model to study fragile X mental retardation
THEDUTCHBELGIANFRAGILEXCONSOR (1994) · Cell · doi:10.1016/0092-8674(94)90569-x · Cited by 1,108
Research works printed but not linked: 1
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Cited by
Sorted by citations
Items 1,101–1,200 of 1,472
Mouffok, I., Lahogue, C., Cailly, T., et al. (2024) · Brain Sciences · doi:10.3390/brainsci14121281 · Cited by 4
Zhang, X., Fu, C., Wang, M., Feng, D., Wang, H., Li, H., Liu, X., Zeng, L., Li, L., & Yao, P. (2025) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.250087 · Cited by 4
Novel behavioral tasks for the measurement of social motivation in mice: a comparison across strains
Wells, C., Huddleston, K. P., Brown, S., Razzaq, F., Chick, D., & Rogers, T. D. (2026) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2025.1678147 · Cited by 4
Sociability: Comparing the Effect of Chlorpyrifos with Valproic Acid
Morales‐Navas, M., Pérez-Fernández, C., Castaño-Castaño, S., Sánchez-Gil, A., Colomina, M. T., Leinekugel, X., & Sánchez-Santed, F. (2024) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-024-06263-z · Cited by 8
Kelberman, M. A., Winther, K. E., Medvedeva, Y. M., & Donaldson, Z. R. (2024) · Hormones and Behavior · doi:10.1016/j.yhbeh.2024.105647 · Cited by 4
Effects of Cannabidiol Isolated or in Association With Risperidone in an Animal Model of Autism
da Costa, M. D. A., Fernandes, G. Z., Maiochi, E., Ebs, M. F. P., Darós, F. D. S., Bolan, S. J., Costa, R. R. N., de Rezende, V. L., da Silva, G. C., de Bitencourt, R. M., et al. (2024) · Developmental Neurobiology · doi:10.1002/dneu.22955 · Cited by 10
Gabriel, G. C., Yagi, H., Tan, T., Bais, A. S., Glennon, B. J., Stapleton, M. C., Huang, L., Reynolds, W. T., Shaffer, M. G., Ganapathiraju, M. K., et al. (2025) · Nature Communications · doi:10.1038/s41467-024-55741-6 · Cited by 5
Ghimire, S., Kreilaus, F., Porto, R. R., Anderson, L. L., Yerbury, J. J., Arnold, J. C., & Karl, T. (2025) · Psychopharmacology · doi:10.1007/s00213-025-06785-z · Cited by 4
“The SPT was used to measure social approach behaviour (i.e. sociability) and social recognition memory as previously published (Moy et al. 2004) with minor alterations (Cheng et al. 2014a).”
Sandoval, K. C., Rychlik, J., & Choe, K. Y. (2025) · eNeuro · doi:10.1523/eneuro.0196-24.2025 · Cited by 8
“…during social investigation of unfamiliar conspeci fi cs Previous studies have shown that rodents prefer investigating unfamiliar conspeci fi cs (Moy et al., 2004; Dumais et al., 2016) while others have shown the opposite (Pearson et al., 2010; Lu et al., 2019; Lu and Hu, 2021) or lack any…”
Zizza, M., Fazzari, G., Lorenzo, M. D., Alò, R., Bruno, R., Laforgia, V., Canonaco, M., & Facciolo, R. M. (2022) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2022.107094 · Cited by 4
Effects of Congenital Blindness on Ultrasonic Vocalizations and Social Behaviors in the ZRDBA Mouse
Bouguiyoud, N., Morales-Grahl, E., Bronchti, G., Frasnelli, J., Roullet, F., & Aïn, S. A. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.884688 · Cited by 5
“Furthermore, this apparent preference for exploring the environment over engaging in social interactions with a congener resembles the social deficits described in mouse models of autism (Moy et al., 2004; McFarlane et al., 2008; Silverman et al., 2010).”
BackgroundAhlers‐Dannen, K. E., Yang, J., Spicer, M. M., Fu, D., DeVore, A. N., & Fisher, R. A. (2024) · Journal of Human Genetics · doi:10.1038/s10038-024-01220-1 · Cited by 4
“3A) [21, 22].”
Pirri, F., Burke, F. F., & McCormick, C. M. (2024) · PLoS ONE · doi:10.1371/journal.pone.0311920 · Cited by 4
Neuroprotective Effects of VEGF-B in a Murine Model of Aggressive Neuronal Loss with Childhood Onset
Pérez-Revuelta, L., Pérez-Boyero, D., Pérez-Martín, E., Cabedo, V. L., de Meneses, P. G. T., Weruaga, E., Díaz, D., & Alonso, J. R. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26020538 · Cited by 4
“The three-chamber social preference test was performed to analyze social behavior in a white Plexiglas box divided into three connected rooms [6,20,80].”
Fauré, L. M. P., Gauzin, S., Lejards, C., Rampon, C., & Verret, L. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.106799 · Cited by 5
Uehara, J. M., Acosta, M. G., Bello, E. P., & Belforte, J. E. (2025) · Neuropsychopharmacology · doi:10.1038/s41386-025-02051-0 · Cited by 4
Neural mechanisms underlying strain preference behaviour and plasticity in mice
Peng, K., Tan, L.-L., You, S., Li, J., Xu, Y., Chen, J.-Y., Wu, M. H., Qin, L., & Zhang, X. (2025) · Scientific Reports · doi:10.1038/s41598-025-90885-5 · Cited by 4
“The three-chamber social interaction test is commonly employed to assess social interaction behaviour in mice 5 .”
Rappeneau, V., Tobinski, A.-M., Guevara, L. M. C., Meyer, N., Jüngling, K., & Touma, C. (2025) · Behavioural Brain Research · doi:10.1016/j.bbr.2025.115530 · Cited by 4
“In the three-chamber sociability and social novelty tests, the innate social tendencies of mice were examined [24].”
Hippocampal CA2 Region: A New Player in Social Dysfunctions
Mou, X. (2016) · Journal of Neurology & Neurophysiology · doi:10.4172/2155-9562.1000357 · Cited by 3
“An increasing body of evidences suggests that CA2 itself is far more than a passive transition region between CA1 and CA3 but a functional unit [32-40].”
BackgroundRestoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice
Chen, Y., Milenkovic, M., Horsfall, W., Salahpour, A., Soderling, S. H., & Ramsey, A. J. (2018) · PLOS ONE · doi:10.1371/journal.pone.0199341 · Cited by 5
Why does lifelong conventional housing reduce the sociability of female mice?
Kitchenham, L., Nazal, B., Adcock, A., Nip, E., MacLellan, A., & Mason, G. J. (2021) · Applied Animal Behaviour Science · doi:10.1016/j.applanim.2021.105532 · Cited by 4
Adil, K. J., Remonde, C. G., Gonzales, E. L., Boo, K.-J., Kwon, K. J., Kim, D. H., Kim, H. J., Cheong, J. H., Shin, C. Y., & Jeon, S. J. (2022) · Biomolecules & Therapeutics · doi:10.4062/biomolther.2021.194 · Cited by 4
“Sociability (Phase 1) is evaluated by tracking the rodent’s exploration on a stranger rodent in a wire cage over an empty cage, and social preference (Phase 2) compares a rodent’s preference to a novel stranger rodent to an already familiar one (Moy et al., 2004).”
BackgroundHernández‐Pérez, O. R., Hernández, V. S., Zetter, M. A., Eiden, L. E., & Zhang, L. (2022) · Journal of Neuroendocrinology · doi:10.1111/jne.13202 · Cited by 4
“…these observations, we devised a behavioral experiment using 48 h of water deprivation (WD48) and the three-chamber social interaction test (3CST), 22,23 designed to quantify the levels of sociability, defined as the tendency to approach and remain proximal to an unfamiliar conspecific (hereafter…”
Liu, B., Qian, Y., & Wang, J. (2023) · BMC Neuroscience · doi:10.1186/s12868-023-00787-3 · Cited by 5
Al-Dossari, A. M., Al‐Harbi, L. N., Al-Otaibi, N. M., Almubarak, A., Almnaizel, A. T., Alshammari, G. M., Shamlan, G. H., Alshatwi, A. A., & El-Ansary, A. K. (2023) · Metabolites · doi:10.3390/metabo13040497 · Cited by 4
“Normal rats will spend more time with the conspecific than with the empty room, whereas rats with impaired social interaction will spend more time with the empty chamber than with the conspecific [21].”
BackgroundOphir, O., Levy, G., Bar, E., Kimchi-Feldhorn, O., Rokach, M., Sfadia, G. E., & Barak, B. (2023) · Biomedicines · doi:10.3390/biomedicines11082273 · Cited by 4
“To study social behavior, the three-chamber social interaction test was used [34,35].”
MethodAssessment of autism-relevant behaviors in C57BKS/J leptin receptor deficient mice
Greene, S. M., Sanchez, Y. R., Pathapati, N., Davis, G. N., & Gould, G. G. (2021) · Hormones and Behavior · doi:10.1016/j.yhbeh.2020.104919 · Cited by 5
Ukkirapandian, K., Kayalvizhi, E., Revathy, K., Brindha, T. R., Rangasmy, M., & Chandrasekar, M. (2021) · Biomedicine · doi:10.51248/.v41i1.526 · Cited by 4
“The time spent with mouse chamber and empty chamber are compared (41).”
BackgroundBehavioral and Neurological Phenotyping in the Mouse
Tucci, V., Blanco, G., & Nolan, P. M. (2006) · Wiley eBooks · doi:10.1002/9783527611942.ch6 · Cited by 4
de León-Reyes, N. S., Díaz, P. S., Nogueira, R., Ruiz-Pino, A., Nomura, Y., de Solis, C. A., Schulkin, J. A., Asok, A., & Leroy, F. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.03.15.484224 · Cited by 4
Yao, I., Takao, K., Miyakawa, T., Ito, S., & Setou, M. (2011) · PLoS ONE · doi:10.1371/annotation/1bf38b37-ee2e-41fb-bad4-ed719b07c6c0 · Cited by 5
β-hydroxybutyrate improves convulsions in mice carrying the GRIN1 Y647S/+ pathogenic variantPreprint
Sullivan, M. T., Tidball, P., Yan, Y., Intson, K., Chen, W., Xu, Y., Venkatesan, S., Horsfall, W., Georgiou, J., Finnie, P. S. B., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.08.21.608984 · Cited by 4
Walker, S. L., & Glasper, E. R. (2024) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2024.101162 · Cited by 3
Yoo, M. H., Kim, T.-Y., Kim, H.-K., Yoo, J., Lee, B., & Koh, J. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.118031 · Cited by 5
Exploring rodent prosociality: A conceptual framework
Charron, V., Talbot, J., & Plamondon, H. (2025) · Translational Neuroscience · doi:10.1515/tnsci-2025-0375 · Cited by 3
“…(i.e., C57BL/6J, DBA/2J, FVB/NJ, A/J, and B6129PF2/J hybrids) revealed that A/J mice displayed signi fi cantly less interest in spending time with a congener in a social novelty test compared to the other tested strains, which could be explained by the hypolocomotion displayed by the A/J mice [148].”
Revealing the Body Language of Social Interaction in Free-Moving Mice Using BL-BERT
Han, Y., Jiang, Z., Ju, F., Wang, L., Liu, Q., & Wei, P. (2025) · Tsinghua Science & Technology · doi:10.26599/tst.2025.9010086 · Cited by 3
Adolescent stress accelerates postpartum novelty recognition impairment in 5xFAD mice
Leitzel, O., de Oliveira, J. F., Khedr, S., Ariste, L., Robel, S., Kano, S., Arrant, A. E., & Niwa, M. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1366199 · Cited by 3
Morel, C., Paoli, J., Camonin, C., Marchal, N., Grova, N., & Schroeder, H. (2024) · NeuroToxicology · doi:10.1016/j.neuro.2024.05.002 · Cited by 4
Raymond, J., Morin, A., Bradley-Garcia, M., & Plamondon, H. (2024) · Nutrients · doi:10.3390/nu16142350 · Cited by 3
“On PND93, the three-chamber SIT/social preference test (SP) was used to assess rodents’ social affiliation/motivation and social memory/preference for social novelty [50].”
MethodThe neural basis of affective empathy: What is known from rodents
Peng, S., Li, M., Yang, X., & Xie, W. (2025) · Neuropharmacology · doi:10.1016/j.neuropharm.2025.110347 · Cited by 3
Li, J., Zhang, N., Ren, W., Li, L., Sun, Y., Hou, Y., Song, S., Pan, L., Sun, Y., Zhang, K., et al. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111319 · Cited by 3
“There were three phases in the three-chamber social preference test (Moy et al., 2004).”
Allan, N. P., Torres, A., Corley, M. J., Yamamoto, B. Y., Balaan, C., Yamauchi, Y., Peres, R., Qin, Y., Khadka, V. S., Deng, Y., et al. (2025) · Cells · doi:10.3390/cells14151201 · Cited by 4
“Files were analyzed using Avisoft SASLab Pro software (Avisoft Bioacoustics, Glienicke/Nordbahn, Germany) with a 512 FFT, Hamming window, and 75% overlap, resulting in ~488 Hz frequency resolution [24,25].”
Schneider, T., & Przewo̵cki, R. (2011) · InTech eBooks · doi:10.5772/20391 · Cited by 2
“This can be best done in an automated three-chambered apparatus in which social interactions, social recognition, and social memory can also be scored (Moy et al., 2004; Nadler et al., 2004).”
BackgroundModeling Hypoxia-Induced Seizures and Hypoxic Encephalopathy in Developing Brain
Sun, H., & Jensen, F. E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-804066-9.00048-1 · Cited by 3
Domadenik, A. (2018) · Acta agriculturae Slovenica · doi:10.14720/aas.2018.112.1.3 · Cited by 3
“Therefore, decision-making is studied, and it is dependent on whether ASD mouse will choose to spend more time in a chamber with another novel mouse or in a chamber with a novel object (Moy et al., 2004).”
BackgroundCirillo, E., Minosi, P., Marzoli, F., et al. (2019) · IEEE International Conference on RFID Technology and Applications (RFID-TA) · doi:10.1109/rfid-ta.2019.8892188 · Cited by 3
“"Sociability" is defined as propensity to spend time with another mouse, as compared to time spent alone in an identical but empty chamber; "preference for social novelty" as propensity to spend time with a previously unencountered mouse rather than with a familiar mouse [33].”
BackgroundTabbaa, M., Moses, A., & Hammock, E. A. D. (2021) · PLoS ONE · doi:10.1371/journal.pone.0260199 · Cited by 3
“, (2004), wherein a rectangular testing apparatus is equally divided into two outer chambers and a center chamber [37].”
BackgroundLopuch, A. J., Swinehart, B. D., Widener, E. L., Holley, Z. L., Bland, K. M., Handwerk, C. J., Brett, C. A., Cook, H. N., Kalinowski, A. R., Rodriguez, H. V., et al. (2022) · BMC Neuroscience · doi:10.1186/s12868-022-00691-2 · Cited by 3
“A prior study has shown that sociability and preference for social novelty is similar in both females and males, when the stranger mice presented are males [34].”
BackgroundMethodInfluentialSiegel, A. E., Bianchi, D. W., & Guedj, F. (2023) · Journal of Neuroscience Research · doi:10.1002/jnr.25160 · Cited by 4
Rawlings-Mortimer, F., Gullino, L. S., Rühling, S., Ashton, A., Barkus, C., & Johansen‐Berg, H. (2023) · PLoS ONE · doi:10.1371/journal.pone.0281264 · Cited by 3
Hou, Y., Park, J. H., Dan, X., Chu, X., Yang, B., Hussain, M., Croteau, D. L., & Bohr, V. A. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106092 · Cited by 3
Effects of chronic sleep restriction on the neuro‐phenotypes of Ctnnd2 knockout mice
Xu, M., Wang, X., Wang, L., Wang, S., Deng, J., Wang, Y., Li, Y., Pan, S., Liao, A., Tao, Y., et al. (2023) · Brain and Behavior · doi:10.1002/brb3.3075 · Cited by 3
“…conspecific and the mice were postpubertal and not gonadectomized, the results of the three-chamber assay are reliable because they contain the target stranger within an inverted round wire cage that avoids potential confounders resulting from aggressive or sexual interactions (Moy et al., 2004).”
BackgroundXue, B., Ma, Y.-Y., Zhu, J.-Y., Mu, Y., Li, Y., Shen, F., Liang, J., & Zhang, J. (2023) · Animal Cognition · doi:10.1007/s10071-023-01798-7 · Cited by 3
“The 3-chambered social interaction test was performed as previous studies described to assess sociability and social novelty preference (Ahire et al. 2021; García-Díaz et al. 2019; Hughes et al. 2021; Klinger et al. 2019; Moy et al. 2004; Song and Kim 2021).”
MethodCharacterization of Behavioral Phenotypes in Heterozygous DAT Rat Based on Pedigree
Zanfino, G., Puzzo, C., Laurenzi, V. D., & Adriani, W. (2023) · Biomedicines · doi:10.3390/biomedicines11092565 · Cited by 3
“The test was performed using a modified version of standard protocols [42].”
MethodKhorassani, Y. M., Moghimi, A., Khakzad, M. R., Fereidoni, M., Hassani, D., & Gah, J. T. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1385189 · Cited by 4
Eğilmez, C. B., Pazarlar, B. A., Erdoğan, M. A., Uyanıkgil, Y., & Erbaş, O. (2024) · International Journal of Developmental Neuroscience · doi:10.1002/jdn.10335 · Cited by 3
“The sociability test was performed as previously described with minor modifications (Erbas et al., 2018; Moy et al., 2004) Briefly, a Plexiglas cage (40 (cid:4) 90 (cid:4) 40 cm) was divided into three equal regions (40x30x40 cm).”
Prairie voles seek social contact with peer companions during immune challenge
Young, G. K., Chernyak, D., Naik, G. A., Song, S. E., & Beery, A. K. (2024) · Hormones and Behavior · doi:10.1016/j.yhbeh.2024.105653 · Cited by 6
“…non-monogamous rodents such as rats and mice, there is little evidence for selective peer relationships, as novel conspecifics tend to be of greater interest to an individual rat or mouse (Hackenberg et al., 2021; Moy et al., 2004; Schweinfurth et al., 2017; Beery, 2018; Beery and Shambaugh, 2021).”
Duarte, R., Ribeiro-Barbosa, É. R., Ferreira, F. R., Espíndola, F. S., & Spini, V. B. M. G. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111188 · Cited by 3
The Schizophrenia Risk Gene Product Mir-137 Alters Presynaptic Plasticity
Siegert, S., Seo, J., Kwon, E. J., Rudenko, A., Cho, S., Wang, W., Flood, Z., Martorell, A. J., Ericsson, M., Mungenast, A. E., et al. (2017) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2016.09.595 · Cited by 3
iHELMET: A 3D-printing solution for safe endoscopic Ca2+ recording in social neuroscience
Saxena, K., Spooner, P. A., Mitchell‐Heggs, R., & Morris, R. (2021) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2021.109109 · Cited by 3
“One solution is to create barriers between the interacting animals as in the classic 3chamber sociability / social novelty test (Crawley, 2004; Moy et al., 2004).”
BackgroundDémosthènes, A., Sion, B., Giraudet, F., Moisset, X., Daulhac, L., Eschalier, A., & Bégou, M. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2021.789432 · Cited by 3
“For EAE clinical score, two-way ANOVA in Cohorts 1 and 2 showed a significant main effect of DPI [F(40,880) = 27.”
InfluentialSocial recognition and short‐term memory in two taxa of striped mouse with differing social systems
Neves, C. N., & Pillay, N. (2022) · Journal of Experimental Zoology Part A Ecological and Integrative Physiology · doi:10.1002/jez.2590 · Cited by 3
Assessing Dyadic Social Interactions in Rodent Models of Neurodevelopmental Disorders
Schiavi, S., Manduca, A., Carbone, E., Buzzelli, V., & Trezza, V. (2022) · Neuromethods · doi:10.1007/978-1-0716-2569-9_10 · Cited by 3
Semax corrects brain dysfunction caused by prenatal introduction of valproic acid
Малышев, А. В., Razumkina, E. V., Дубынин, В. А., & Myasoedov, N. F. (2013) · Doklady Biological Sciences · doi:10.1134/s0012496613030046 · Cited by 3
Animal Behavior: Socializing Octopus
Gutnick, T., & Kuba, M. J. (2018) · Current Biology · doi:10.1016/j.cub.2018.08.006 · Cited by 3
Mehta, R., Bhandari, R., & Kuhad, A. (2021) · Metabolic Brain Disease · doi:10.1007/s11011-021-00811-7 · Cited by 3
Bozkurt, M. F., Bhaya, M. N., Sever, İ. H., Özkul, B., & Erbaş, O. (2022) · Bangladesh Journal of Pharmacology · doi:10.3329/bjp.v17i2.59412 · Cited by 3
“Social behavioral tests have been tested in other studies (Moy et al., 2004; Silverman et al., 2010).”
MethodBelle, J. E. L., Sperry, J., Ludwig, K., Harris, N. G., Caldwell, M., & Kornblum, H. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.02.10.942870 · Cited by 3
“This test is commonly referred to as the three-chambered social approach task for mice where the mouse can freely move between 3 chambers containing either nothing (center chamber), a novel object (empty mesh or slatted cup) or a novel mouse in a mesh or slatted cup (Moy et al., 2004).”
MethodPangrazzi, L., Cerilli, E., Balasco, L., Dall‘O’, G. M., Chelini, G., Pastore, A., Weinberger, B., & Bozzi, Y. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.03.13.584809 · Cited by 3
Kozlova, E. V., Denys, M. E., Bishay, A. E., Luna, C. N., Angelis, M. D., Campoy, L., Habbal, A., Lam, A. A., Luvsanravdan, N., Colton, A. G., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.07.28.667293 · Cited by 2
Capturing Complexity: Experimental Systems And Epistemic Scaffolds In Animal Behavior Genetics
Nelson, N. C. (2011) · eCommons (Cornell University) · Cited by 3
Uchewa, O. O., Shallom, E. S., Egwu, O. A., et al. (2022) · AIMS neuroscience · doi:10.3934/neuroscience.2022026 · Cited by 2
“Various neuropsychiatric disorders are characterized by social behavior and recognition alterations, including depression, autism spectrum disorders, bipolar disorders, obsessive-compulsive disorders, and schizophrenia [36].”
BackgroundYabe, T., Mitsui, Y., Ohnishi, M., Tanigawa, R., Tanizaki, M., Sugiyama, R., Kiriyama, N., Otsuka, A., & Komada, M. (2024) · Behavioural Brain Research · doi:10.1016/j.bbr.2024.115367 · Cited by 3
Tzanoulinou, S., Astori, S., Grandi, L. C., Gullo, F., Kalusivikako, R., Rai, S., Limorenko, G., Tafti, M., Becchetti, A., & Vassalli, A. (2026) · Biological Psychiatry · doi:10.1016/j.biopsych.2026.05.022 · Cited by 5
Perinatal hypoxia-mediated neurodevelopment abnormalities in congenital heart disease mouse model
Chen, R., Wang, H., Zeng, L., He, J., Liu, X., Ji, X., Yao, P., & Gu, S. (2025) · Molecular Medicine · doi:10.1186/s10020-025-01158-w · Cited by 2
“Parameters like time spent in each chamber were recorded (Wang et al. 2019; Moy et al. 2004).”
Echefu, B. E., Becker, M., Stein, D. J., & Ornoy, A. (2025) · NeuroSci · doi:10.3390/neurosci6020027 · Cited by 7
“The primary aim is to assess the degree of social engagement, whereby failure to interact more frequently or reciprocate behaviors is indicative of asocial traits akin to NDDs [50,51].”
Demirtas, H., Açıkgöz, B., Arslankiran, A., Dalkiran, B., Kıray, A., Kıray, M., Dayı, A., & Aksu, İ. (2025) · Neuropeptides · doi:10.1016/j.npep.2025.102532 · Cited by 3
Uchegbu, C., Nguyen, T., Sood, I., Blankenship, K., He, H., Stanwood, G. D., Vied, C., & Graham, D. L. (2025) · Neuropharmacology · doi:10.1016/j.neuropharm.2025.110583 · Cited by 2
Rebik, A., Broshevitskaya, N. D., Riga, V. D., Aleksandrov, P. L., Zaichenko, M. I., & Midzyanovskaya, I. S. (2025) · ALPHA PSYCHIATRY · doi:10.31083/ap43990 · Cited by 2
Zárate-López, D., García-Carrillo, R., Castro‐Sánchez, L., Gálvez‐Contreras, A. Y., & González-Pérez, Ó. (2025) · Archives of Medical Research · doi:10.1016/j.arcmed.2025.103254 · Cited by 2
Aghadoukht, A., Nasehi, M. M., Ebrahimi-Ghiri, M., Sadat‐Shirazi, M., Mahboubi, S., & Zarrindast, M. (2025) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2025.152353 · Cited by 2
Friesen, C. N., Hartswick, D., Selke, A., Vries, G. J. D., & Petrulis, A. (2025) · Hormones and Behavior · doi:10.1016/j.yhbeh.2025.105792 · Cited by 3
Myelin, white matter, and social deficits in autism spectrum disorder
Kimchi-Feldhorn, O., Nir, A., & Barak, B. (2025) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-25-00366 · Cited by 4
“Animal studies have provided valuable insight into genetic-based ASD and the associated social behaviors (Moy et al., 2004; Bohlen et al., 2023; Crawley, 2023; Fischer et al., 2024), and some also further delved into the relationship between social behavior and myelin properties.”
Medeiros, D., Polepalli, L., Li, W., & Pozzo‐Miller, L. D. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00360.2025 · Cited by 2
Traetta, M. E., Codagnone, M. G., Litvak, E., Corpa, M. J. M., Uccelli, N. A., Zárate, S., & Reinés, A. G. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111591 · Cited by 2
Ochi, S., Inada, H., & Osumi, N. (2026) · Lab Animal · doi:10.1038/s41684-025-01668-4 · Cited by 2
“Similarly, the three-chamber social interaction test assesses sociability by comparing the time a mouse interacts with a novel mouse versus an empty chamber, offering insights into social preferences 5 .”
Effects of Chronic 100 mg/kg Cannabidiol Treatment in Male Double Transgenic APPSwe/PS1∆E9 Mice
Watt, G., Olaya, J. C., Muench, G. W., Garner, B., & Karl, T. (2026) · Pharmaceuticals · doi:10.3390/ph19030374 · Cited by 3
“Sociability and social recognition memory [63] were evaluated using the SPT, as described previously [61].”
Islam, M. S., Sachi, S., & Hasan, M. R. (2021) · World Journal of Biology Pharmacy and Health Sciences · doi:10.30574/wjbphs.2021.5.3.0022 · Cited by 2
“"Sociability" in this case is defined as tendency to expend time with another mouse, as compared to time spent alone in an identical empty chamber [14].”
BackgroundOndek, K., Nasirishargh, A., Dayton, J. R., Nuno, M. A., & Cruz‐Orengo, L. (2021) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2021.100262 · Cited by 3
Cholesterol in autism spectrum disorders
Franco, R., Rivas‐Santisteban, R., Navarro, G., & Reyes‐Resina, I. (2021) · Exploration of Neuroprotective Therapy · doi:10.37349/ent.2021.00003 · Cited by 2
Does the stranger mouse strain matter to female BTBR mice?
DiLiberto, E., Phatarpekar, S., Theodorakis, K., & Chadman, K. K. (2022) · Behavioural Brain Research · doi:10.1016/j.bbr.2022.114132 · Cited by 2
“The three-chambered social approach test is commonly used to test for sociability in mice [3,4].”
Female rats prefer to forage food from males, an effect that is not influenced by stress
Zhou, S.-F., Li, S.-J., Zhao, T.-S., Liu, Y., Li, F., Cui, Y., & Li, F. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114597 · Cited by 4
Babicola, L., Mancini, C., Riccelli, C., Segni, M. D., Passeri, A., Municchi, D., D’Addario, S. L., Andolina, D., Cifani, C., Cabib, S., et al. (2023) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2023.110842 · Cited by 2
Varga, A., Kedves, R., Sághy, K., Garab, D., Zádor, F., Lendvai, B., Lévay, G. I., & Román, V. (2024) · Pharmaceuticals · doi:10.3390/ph17070939 · Cited by 2
Singh, Y., Sodhi, R. K., Kumar, H., Bishnoi, M., Bhandari, R., & Kuhad, A. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176902 · Cited by 2
A fully automated social interaction chamber for studying social threat learning in mice
McTaggart, E. M., Miller, N. W., Ortiz-Juza, M. M., Pégard, N. C., & Rodríguez-Romaguera, J. (2024) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2024.1481935 · Cited by 2
Host genetics maps to behaviour and brain structure in developmental mice
Asbury, S., Lai, J., Rilett, K. C., Haqqee, Z., Darwin, B. C., Ellegood, J., Lerch, J. P., & Foster, J. A. (2025) · Behavioral and Brain Functions · doi:10.1186/s12993-024-00261-y · Cited by 2
“At P24, sociability was tested using a 3-chamber apparatus [14, 31].”
Larosa, A., Zhang, T. R., Wong, A. S., Fung, C. Y. H., Long, X. L. Y. (., Singh, P., Fung, B. C. M., & Wong, T. P. (2025) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2025.100455 · Cited by 2
“(E) Average percentage of reactivated dorsal CA1 neurons in the SIT (con: n = 5 – 6, res: n = 10, sus: n = 5 – 6).”
Piccin, A., Allain, A., Baufreton, J., Bertrand, S. S., & Contarino, A. (2024) · eLife · doi:10.7554/elife.100849.3 · Cited by 2
A new two-hit animal model for schizophrenia research: Consequences on social behavior
Hakenova, K., Mikulecká, A., Holubová, K., Chvojková, M., Šlamberová, R., Jur̀čovičová, J., Čechová, B., Poništ, S., Horáček, J., & Valeš, K. (2025) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2025.05.012 · Cited by 4
“Many studies validated the procedure ’ s utility for evaluating social behavior in rats and mice (Bitanihirwe et al., 2010; Mikulecka et al., 2019; Moy et al., 2004; van der Kooij and Sandi, 2012).”
Metadata
- Authors
- Moy, S. S., Nadler, J. J., Perez, A., Barbaro, R. P., Johns, J. M., Magnuson, T. R., Piven, J., & Crawley, J. N.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- National Institute of Mental Health (US)
- Corresponding author
- Moy, S. S.
- Venue
- Genes, Brain and Behavior
- Publisher
- Wiley
- Published
- 2004-04-29
- Volume
- 3
- Issue
- 5
- Pages
- 287-302
- ISSN
- 1601-183X (ISSN-L)
- 1601-1848
- OpenAlex
- W2109091674
- Cited by
- 1,522
- References
- 80
- Citations by year
- 2026: 93 · 2025: 99 · 2024: 99 · 2023: 98 · 2022: 121 · 2021: 110 · 2020: 109 · 2019: 114 · 2018: 98 · 2017: 65 · 2016: 83 · 2015: 72 · 2014: 65 · 2013: 53 · 2012: 57
- FWCI
- 6.66
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Genes Brain & Behavior (publishedVersion)
- PubMed (publishedVersion)
- Funders
- North Carolina State University
- National Institute for Health and Care Research
- National Institutes of Health (5u54mh066418-05)
- National Institute of Mental Health (U54 MH 66418, MH66418)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (P30HD003110)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Keywords
- sociability, autism spectrum disorder, mouse models of autism, inbred mouse strains, social interaction deficits, social avoidance, C57BL/6J mice, DBA/2J, A/J, sex differences, age differences
- MeSH terms
- Age Factors, Analysis of Variance, Animals, Autistic Disorder, Disease Models, Animal, Exploratory Behavior, Female, Locomotion, Male, Mice, Inbred C57BL, Mice, Inbred DBA, Mice, Inbred Strains, Sex Factors, Social Behavior, Species Specificity, Reproducibility of Results, Rotarod Performance Test, Mice
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