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Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
Open accessAbstract
We report a strategy to create photodegradable poly(ethylene glycol)–based hydrogels through rapid polymerization of cytocompatible macromers for remote manipulation of gel properties in situ. Postgelation control of the gel properties was demonstrated to introduce temporal changes, creation of arbitrarily shaped features, and on-demand pendant functionality release. Channels photodegraded within a hydrogel containing encapsulated cells allow cell migration. Temporal variation of the biochemical gel composition was used to influence chondrogenic differentiation of encapsulated stem cells. Photodegradable gels that allow real-time manipulation of material properties or chemistry provide dynamic environments with the scope to answer fundamental questions about material regulation of live cell function and may affect an array of applications from design of drug delivery vehicles to tissue engineering systems.
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“The viscoelastic profile of hydrogels has also been shown to define the mechanical confinement of growing organoids66.”
From Organoids (2022) · cites this paper as [66]
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“Manipulating synthetic hydrogels using methods such as electrospinning125, photopatterning126,127, spraying of microspheres128, inkjet and 3D printing129, or microfluidic channels130 further enables control over the shape and size of the organoids.”
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Cites
Matrix elasticity directs stem cell lineage specification
Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915
New Perspectives in Cell Adhesion: RGD and Integrins
Ruoslahti, E. I., & Pierschbacher, M. D. (1987) · Science · doi:10.1126/science.2821619 · Cited by 4,875
Lutolf, M. P., & Hubbell, J. A. (2005) · Nature Biotechnology · doi:10.1038/nbt1055 · Cited by 4,551
Exploring and Engineering the Cell Surface Interface
Stevens, M. M., & George, J. H. (2005) · Science · doi:10.1126/science.1106587 · Cited by 2,607
Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers
Silva, G. A., Czeisler, C. M., Niece, K. L., Beniash, E., Harrington, D. A., Kessler, J. A., & Stupp, S. I. (2004) · Science · doi:10.1126/science.1093783 · Cited by 2,179
Young, R. J., & Lovell, P. A. (1981) · CRC Press eBooks · doi:10.1007/978-1-4615-3478-5 · Cited by 2,152
Myotubes differentiate optimally on substrates with tissue-like stiffness
Engler, A. J., Griffin, M. A., Sen, S., Bönnemann, C. G., Sweeney, H. L., & Discher, D. E. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200405004 · Cited by 1,743
Advances in biomaterials, drug delivery, and bionanotechnology
Langer, R., & Peppas, N. A. (2003) · AIChE Journal · doi:10.1002/aic.690491202 · Cited by 982
Microengineered hydrogels for tissue engineering
Khademhosseini, A., & Langer, R. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.07.021 · Cited by 830
Microfabrication meets microbiology
Weibel, D. B., DiLuzio, W. R., & Whitesides, G. M. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1616 · Cited by 806
Research works printed but not linked: 2
- 10.1021/bm060086 · DOI
- S. J. Bryant, K. S. Anseth, in Scaffolding in Tissue Engineering, P. X. Ma, J. Elisseeff, Eds. (Marcel Dekker, New York, 2005), pp. 69–88.
Cited by
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Advances in engineering hydrogels
Zhang, Y. S., & Khademhosseini, A. (2017) · Science · doi:10.1126/science.aaf3627 · Cited by 2,908
Hydrogels as extracellular matrix mimics for 3D cell culture
Tibbitt, M. W., & Anseth, K. S. (2009) · Biotechnology and Bioengineering · doi:10.1002/bit.22361 · Cited by 2,727
Self-citationThree-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size
Loh, Q. L., & Choong, C. (2013) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2012.0437 · Cited by 2,668
A practical guide to hydrogels for cell culture
Caliari, S. R., & Burdick, J. A. (2016) · Nature Methods · doi:10.1038/nmeth.3839 · Cited by 2,075
Designing Cell-Compatible Hydrogels for Biomedical Applications
Seliktar, D. (2012) · Science · doi:10.1126/science.1214804 · Cited by 1,952
Modeling physiological events in 2D vs. 3D cell culture
Duval, K., Grover, H., Han, L.-H., Mou, Y., Pegoraro, A. F., Fredberg, J., & Chen, Z. (2017) · Physiology · doi:10.1152/physiol.00036.2016 · Cited by 1,849
Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix
Guilak, F., Cohen, D. M., Estes, B. T., Gimble, J. M., Liedtke, W., & Chen, C. S. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.06.016 · Cited by 1,872
Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and Efficacy
Petr Klán, A., Šolomek, T., Bochet, C. G., Blanc, A., Givens, R. S., Rubina, M. Y., Popik, V. V., Kostikov, A. P., & Wirz, J. (2012) · Chemical Reviews · doi:10.1021/cr300177k · Cited by 1,846
Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues
Baker, B. M., & Chen, C. S. (2012) · Journal of Cell Science · doi:10.1242/jcs.079509 · Cited by 1,760
Bioactive modification of poly (ethylene glycol) hydrogels for tissue engineering
Zhu, J. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.02.044 · Cited by 1,457
Lü, Y., Aimetti, A. A., Langer, R., & Gu, Z. (2016) · Nature Reviews Materials · doi:10.1038/natrevmats.2016.75 · Cited by 1,448
25th Anniversary Article: Rational Design and Applications of Hydrogels in Regenerative Medicine
Annabi, N., Tamayol, A., Uquillas, J. A., Akbari, M., Bertassoni, L. E., Cha, C., Camci‐Unal, G., Dokmeci, M. R., Peppas, N. A., & Khademhosseini, A. (2014) · Advanced Materials · doi:10.1002/adma.201303233 · Cited by 1,409
Designing materials to direct stem-cell fate
Lütolf, M. P., Gilbert, P. M., & Blau, H. M. (2009) · Nature · doi:10.1038/nature08602 · Cited by 1,409
Lee, K., Silva, E. A., & Mooney, D. J. (2010) · Journal of The Royal Society Interface · doi:10.1098/rsif.2010.0223 · Cited by 1,424
Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?
Chen, Q., Shou, P., Zheng, C., Jiang, M., Cao, G., Yang, Q., Cao, J., Xie, N., Velletri, T., Zhang, X., et al. (2016) · Cell Death & Differentiation · doi:10.1038/cdd.2015.168 · Cited by 1,156
Additive manufacturing of tissues and organs
Melchels, F. P. W., Domingos, M. A. N., Klein, T. J., Malda, J., Bártolo, P., & Hutmacher, D. W. (2011) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.11.007 · Cited by 1,223
Progress and potential in organoid research
Rossi, G., Manfrin, A., & Lutolf, M. P. (2018) · Nature Reviews Genetics · doi:10.1038/s41576-018-0051-9 · Cited by 1,182
Hofer, M., & Lutolf, M. P. (2021) · Nature Reviews Materials · doi:10.1038/s41578-021-00279-y · Cited by 1,184
Soft Materials by Design: Unconventional Polymer Networks Give Extreme Properties
Zhao, X., Chen, X., Yuk, H., Lin, S., Liu, X., & Parada, G. A. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01088 · Cited by 1,177
Mechanical memory and dosing influence stem cell fate
Yang, C., Tibbitt, M. W., Basta, L. P., & Anseth, K. S. (2014) · Nature Materials · doi:10.1038/nmat3889 · Cited by 1,167
Self-citationLanthanide Nanoparticles: From Design toward Bioimaging and Therapy
Dong, H., Du, S., Zheng, X.-Y., Lyu, G.-M., Sun, L., Li, L.-D., Zhang, P., Zhang, C., & Yan, C. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00091 · Cited by 1,133
Zhao, Z., Chen, X., Dowbaj, A. M., Sljukic, A., Bratlie, K., Lin, L., Fong, E. L. S., Balachander, G. M., Chen, Z., Soragni, A., et al. (2022) · Nature Reviews Methods Primers · doi:10.1038/s43586-022-00174-y · Cited by 1,082
Materials as stem cell regulators
Murphy, W. L., McDevitt, T. C., & Engler, A. J. (2014) · Nature Materials · doi:10.1038/nmat3937 · Cited by 947
In situ forming injectable hydrogels for drug delivery and wound repair
Dimatteo, R., Darling, N. J., & Segura, T. (2018) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2018.03.007 · Cited by 924
3D printing of hydrogels: Rational design strategies and emerging biomedical applications
Li, J., Wu, C., Chu, P. K.-H., & Gelinsky, M. (2020) · Materials Science and Engineering R Reports · doi:10.1016/j.mser.2020.100543 · Cited by 899
Advances in Biomaterials for Drug Delivery
Fenton, O. S., Olafson, K. N., Pillai, P. S., Mitchell, M. J., & Langer, R. (2018) · Advanced Materials · doi:10.1002/adma.201705328 · Cited by 890
Cell–extracellular matrix mechanotransduction in 3D
Saraswathibhatla, A., Indana, D., & Chaudhuri, O. (2023) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-023-00583-1 · Cited by 887
Functional and Biomimetic Materials for Engineering of the Three-Dimensional Cell Microenvironment
Huang, G., Li, F., Zhao, X., Ma, Y., Li, Y., Lin, M., Jin, G., Lu, T. J., Genin, G. M., & Xu, F. (2017) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00094 · Cited by 825
Engineering Stem Cell Organoids
Yin, X., Mead, B. E., Safaee, H., Langer, R., Karp, J. M., & Levy, O. (2016) · Cell Stem Cell · doi:10.1016/j.stem.2015.12.005 · Cited by 866
The design of reversible hydrogels to capture extracellular matrix dynamics
Rosales, A. M., & Anseth, K. S. (2016) · Nature Reviews Materials · doi:10.1038/natrevmats.2015.12 · Cited by 770
Self-citationHydrogels in sensing applications
Buenger, D., Topuz, F., & Gröll, J. (2012) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.09.001 · Cited by 778
Design and Applications of Photoresponsive Hydrogels
Li, L., Scheiger, J. M., & Levkin, P. A. (2019) · Advanced Materials · doi:10.1002/adma.201807333 · Cited by 751
Adaptable Hydrogel Networks with Reversible Linkages for Tissue Engineering
Wang, H., & Heilshorn, S. C. (2015) · Advanced Materials · doi:10.1002/adma.201501558 · Cited by 736
Designing degradable hydrogels for orthogonal control of cell microenvironments
Kharkar, P. M., Kiick, K. L., & Kloxin, A. M. (2013) · Chem. Soc. Rev. · doi:10.1039/c3cs60040h · Cited by 717
Self-citationDeForest, C. A., & Anseth, K. S. (2011) · Nature Chemistry · doi:10.1038/nchem.1174 · Cited by 716
Self-citationMacroporous Nanowire Nanoelectronic Scaffolds for Synthetic Tissues
Jia Liu, B., Dvir, T., Jin, L., Tsui, J. H., Qing, Q., Suo, Z., Langer, R., Kohane, D. S., Lieber, C. M., & Tian, B. (2012) · Digital Access to Scholarship at Harvard (DASH) (Harvard University) · Cited by 642
Mechanical characterisation of hydrogel materials
Oyen, M. L. (2013) · International Materials Reviews · doi:10.1179/1743280413y.0000000022 · Cited by 641
3D biofabrication strategies for tissue engineering and regenerative medicine
Bajaj, P., Schweller, R. M., Khademhosseini, A., West, J. L., & Bashir, R. (2014) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071813-105155 · Cited by 632
Moving from static to dynamic complexity in hydrogel design
Burdick, J. A., & Murphy, W. L. (2012) · Nature Communications · doi:10.1038/ncomms2271 · Cited by 573
Sun, G., Zhang, X., Shen, Y.-I., Sebastian, R., Dickinson, L. E., Fox-Talbot, K., Reinblatt, M., Steenbergen, C., Harmon, J. W., & Gerecht, S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1115973108 · Cited by 562
o -Nitrobenzyl Alcohol Derivatives: Opportunities in Polymer and Materials Science
Zhao, H., Sterner, E. S., Coughlin, E. B., & Théato, P. (2012) · Macromolecules · doi:10.1021/ma201924h · Cited by 541
Photoresponsive hydrogels for biomedical applications
Tomatsu, I., Peng, K., & Kros, A. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.06.009 · Cited by 540
Hydrogel scaffolds for tissue engineering: the importance of polymer choice
Spicer, C. D. (2019) · Polymer Chemistry · doi:10.1039/c9py01021a · Cited by 538
Fernández, M., Abbah, S. A., McNamara, L. M., Zeugolis, D. I., Pandit, A. S., & Biggs, M. J. P. (2014) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2014.09.005 · Cited by 524
Supramolecular Chemistry and Self-Assembly in Organic Materials Design
Stupp, S. I., & Palmer, L. C. (2013) · Chemistry of Materials · doi:10.1021/cm403028b · Cited by 522
Self-assembling peptide scaffolds for regenerative medicine
Matson, J. B., & Stupp, S. I. (2011) · Chemical Communications · doi:10.1039/c1cc15551b · Cited by 502
Fan, J., Shi, Z., Lian, M., Li, H., & Yin, J. (2013) · Journal of Materials Chemistry A · doi:10.1039/c3ta10639j · Cited by 498
Light-Responsive Block Copolymer Micelles
Zhao, Y. (2012) · Macromolecules · doi:10.1021/ma300094t · Cited by 497
Mimicking biological functionality with polymers for biomedical applications
Green, J. J., & Elisseeff, J. H. (2016) · Nature · doi:10.1038/nature21005 · Cited by 501
Mandal, A., Clegg, J. R., Anselmo, A. C., & Mitragotri, S. (2020) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10158 · Cited by 508
Pang, Q., Lou, D., Li, S., Wang, G., Qiao, B., Dong, S., Ma, L., Gao, C., & Wu, Z. (2020) · Advanced Science · doi:10.1002/advs.201902673 · Cited by 503
Mondschein, R. J., Kanitkar, A., Williams, C. B., Verbridge, S. S., & Long, T. E. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.06.005 · Cited by 496
Hydrogels for the Repair of Articular Cartilage Defects
Spiller, K. L., Maher, S. A., & Lowman, A. M. (2011) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2011.0077 · Cited by 484
Yang, Y., Shao, Q., Deng, R., Wang, C., Teng, X., Cheng, K., Cheng, Z., Huang, L., Liu, Z., Liu, X., et al. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201107919 · Cited by 467
A photoreversible protein-patterning approach for guiding stem cell fate in three-dimensional gels
DeForest, C. A., & Tirrell, D. A. (2015) · Nature Materials · doi:10.1038/nmat4219 · Cited by 432
Hydrogels: From soft contact lenses and implants to self‐assembled nanomaterials
Kopec̆ek, J. (2009) · Journal of Polymer Science Part A Polymer Chemistry · doi:10.1002/pola.23607 · Cited by 443
Spatiotemporal hydrogel biomaterials for regenerative medicine
Brown, T. E., & Anseth, K. S. (2017) · Chemical Society Reviews · doi:10.1039/c7cs00445a · Cited by 436
Self-citationBioengineering strategies to accelerate stem cell therapeutics
Madl, C. M., Heilshorn, S. C., & Blau, H. M. (2018) · Nature · doi:10.1038/s41586-018-0089-z · Cited by 434
Temperature-responsive compounds as in situ gelling biomedical materials
Moon, H. J., Ko, D. Y., Park, M. H., Joo, M. K., & Jeong, B. (2012) · Chemical Society Reviews · doi:10.1039/c2cs35078e · Cited by 423
Fundamentals and Applications of Photo-Cross-Linking in Bioprinting
Lim, K. S., Galarraga, J. H., Cui, X., Lindberg, G. C. J., Burdick, J. A., & Woodfield, T. B. F. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.9b00812 · Cited by 449
Biomaterials for Bone Regenerative Engineering
Yu, X., Tang, X., Gohil, S. V., & Laurencin, C. T. (2015) · Advanced Healthcare Materials · doi:10.1002/adhm.201400760 · Cited by 435
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Wu, S., & Butt, H. (2015) · Advanced Materials · doi:10.1002/adma.201502843 · Cited by 417
Yan, B., Boyer, J., Habault, D., Branda, N. R., & Zhao, Y. (2012) · Journal of the American Chemical Society · doi:10.1021/ja308876j · Cited by 417
Recent progress of in situ formed gels for biomedical applications
Ko, D. Y., Shinde, U. P., Yeon, B., & Jeong, B. (2012) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2012.08.002 · Cited by 420
Engineered materials for organoid systems
Kratochvil, M. J., Seymour, A. J., Li, T. L., Pașca, S. P., Kuo, C. J., & Heilshorn, S. C. (2019) · Nature Reviews Materials · doi:10.1038/s41578-019-0129-9 · Cited by 430
Chatani, S., Kloxin, C. J., & Bowman, C. N. (2013) · Polymer Chemistry · doi:10.1039/c3py01334k · Cited by 433
Extrusion 3D Printing of Polymeric Materials with Advanced Properties
Jiang, Z., Diggle, B., Tan, M. L., Viktorova, J., Bennett, C. W., & Connal, L. A. (2020) · Advanced Science · doi:10.1002/advs.202001379 · Cited by 436
Liu, X., Jin, X., & Ma, P. X. (2011) · Nature Materials · doi:10.1038/nmat2999 · Cited by 409
In situ elasticity modulation with dynamic substrates to direct cell phenotype
Kloxin, A. M., Benton, J. A., & Anseth, K. S. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.09.025 · Cited by 415
Self-citationTowards organoid culture without Matrigel
Kozlowski, M. T., Crook, C. J., & Ku, H. T. (2021) · Communications Biology · doi:10.1038/s42003-021-02910-8 · Cited by 409
Lee, T. T., García, J. R., Paez, J. I., Singh, A. K., Phelps, E. A., Weis, S., Shafiq, Z., Shekaran, A., del Campo, A., & Garcı́a, A. J. (2014) · Nature Materials · doi:10.1038/nmat4157 · Cited by 408
Spatial and temporal control of the alkyne–azide cycloaddition by photoinitiated Cu(II) reduction
Adzima, B. J., Tao, Y., Kloxin, C. J., DeForest, C. A., Anseth, K. S., & Bowman, C. N. (2011) · Nature Chemistry · doi:10.1038/nchem.980 · Cited by 404
Self-citationPhotoresponsive biomaterials for targeted drug delivery and 4D cell culture
Ruskowitz, E. R., & DeForest, C. A. (2018) · Nature Reviews Materials · doi:10.1038/natrevmats.2017.87 · Cited by 399
Zhang, K., Feng, Q., Fang, Z., Gu, L., & Bian, L. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00071 · Cited by 401
Polymer Networks: From Plastics and Gels to Porous Frameworks
Gu, Y., Zhao, J., & Johnson, J. A. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.201902900 · Cited by 388
Engineering the Regenerative Microenvironment with Biomaterials
Rice, J. J., Martino, M. M., Laporte, L. D., Tortelli, F., Briquez, P. S., & Hubbell, J. A. (2012) · Advanced Healthcare Materials · doi:10.1002/adhm.201200197 · Cited by 397
Chemical strategies to engineer hydrogels for cell culture
Lou, J., & Mooney, D. J. (2022) · Nature Reviews Chemistry · doi:10.1038/s41570-022-00420-7 · Cited by 407
Li, Y., Zhang, Y. S., Akpek, A., Shin, S. R., & Khademhosseini, A. (2016) · Biofabrication · doi:10.1088/1758-5090/9/1/012001 · Cited by 385
Taşaltın, N., Nnamchi, P. S., & Saud, S. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.87879 · Cited by 432
Engineering Stem Cell Self-organization to Build Better Organoids
Brassard, J. A., & Lütolf, M. P. (2019) · Cell stem cell · doi:10.1016/j.stem.2019.05.005 · Cited by 392
Photodegradable, Photoadaptable Hydrogels via Radical-Mediated Disulfide Fragmentation Reaction
Fairbanks, B. D., Singh, S. P., Bowman, C. N., & Anseth, K. S. (2011) · Macromolecules · doi:10.1021/ma200202w · Cited by 378
Self-citationRecent Progress of Polysaccharide‐Based Hydrogel Interfaces for Wound Healing and Tissue Engineering
Zhu, T., Mao, J., Cheng, Y. F., Liu, H., Lv, L., Ge, M., Li, S., Huang, J., Chen, Z., Li, H., et al. (2019) · Advanced Materials Interfaces · doi:10.1002/admi.201900761 · Cited by 381
Photoswitching topology in polymer networks with metal–organic cages as crosslinks
Gu, Y., Alt, E. A., Wang, H., Li, X., Willard, A. P., & Johnson, J. A. (2018) · Nature · doi:10.1038/s41586-018-0339-0 · Cited by 371
Photopolymerization of cell-encapsulating hydrogels: Crosslinking efficiency versus cytotoxicity
Mironi‐Harpaz, I., Wang, D. Y., Venkatraman, S. S., & Seliktar, D. (2012) · Acta Biomaterialia · doi:10.1016/j.actbio.2011.12.034 · Cited by 365
A Review on the Design and Hydration Properties of Natural Polymer-Based Hydrogels
Karoyo, A. H., & Wilson, L. D. (2021) · Materials · doi:10.3390/ma14051095 · Cited by 367
Advances in Hydrogels in Organoids and Organs‐on‐a‐Chip
Liu, H., Wang, Y., Cui, K., Guo, Y., Zhang, X., & Qin, J. (2019) · Advanced Materials · doi:10.1002/adma.201902042 · Cited by 361
Light-Driven Expansion of Spiropyran Hydrogels
Li, C., Iscen, A., Palmer, L. C., Schatz, G. C., & Stupp, S. I. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.0c02201 · Cited by 351
Heparin-functionalized polymeric biomaterials in tissue engineering and drug delivery applications
Liang, Y., & Kiick, K. L. (2013) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.07.031 · Cited by 352
Gaharwar, A. K., Dammu, S. A., Canter, J. M., Wu, C., & Schmidt, G. (2011) · Biomacromolecules · doi:10.1021/bm200027z · Cited by 348
Cross, V. L., Zheng, Y. Y., Choi, N., Verbridge, S. S., Sutermaster, B. A., Bonassar, L. J., Fischbach, C., & Stroock, A. D. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.07.072 · Cited by 347
Yan, C., Altunbaş, A., Yücel, T., Nagarkar, R. P., Schneider, J. P., & Pochan, D. J. (2010) · Soft Matter · doi:10.1039/c0sm00642d · Cited by 342
Gramlich, W. M., Kim, I. L., & Burdick, J. A. (2013) · Biomaterials · doi:10.1016/j.biomaterials.2013.08.089 · Cited by 349
Advances in Bioactive Hydrogels to Probe and Direct Cell Fate
DeForest, C. A., & Anseth, K. S. (2012) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-062011-080945 · Cited by 328
Self-citationBioinspired Materials for Controlling Stem Cell Fate
Fisher, O. Z., Khademhosseini, A., Langer, R., & Peppas, N. A. (2009) · Accounts of Chemical Research · doi:10.1021/ar900226q · Cited by 315
Photoreversible Patterning of Biomolecules within Click‐Based Hydrogels
DeForest, C. A., & Anseth, K. S. (2012) · Angewandte Chemie International Edition · doi:10.1002/anie.201106463 · Cited by 315
Self-citationIn situ cell manipulation through enzymatic hydrogel photopatterning
Mosiewicz, K. A., Kolb, L., van der Vlies, A. J., Martino, M. M., Lienemann, P. S., Hubbell, J. A., Ehrbar, M., & Lutolf, M. P. (2013) · Nature Materials · doi:10.1038/nmat3766 · Cited by 308
Dynamic phototuning of 3D hydrogel stiffness
Stowers, R. S., Allen, S. C., & Suggs, L. J. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1421897112 · Cited by 309
Hydrogels for Engineering of Perfusable Vascular Networks
Liu, J., Zheng, H., Poh, P. S. P., Machens, H., & Schilling, A. F. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160715997 · Cited by 325
Chatterjee, K., Lin‐Gibson, S., Wallace, W. E., Parekh, S. H., Lee, Y. J., Cicerone, M. T., Young, M. F., & Simon, C. G. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.03.024 · Cited by 307
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Self-citation
Metadata
- Authors
- Kloxin, A. M., Kasko, A. M., Salinas, C. N., & Anseth, K. S.
- Affiliations
- Howard Hughes Medical Institute (US)
- Corresponding author
- Kasko, Andrea M.
- Anseth, Kristi S.
- Venue
- Science
- Published
- 2009-04-03
- Volume
- 324
- Issue
- 5923
- Pages
- 59-63
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- PMC
- PMC2756032
- OpenAlex
- W2067897176
- Cited by
- 1,748
- References
- 34
- Citations by year
- 2026: 62 · 2025: 69 · 2024: 60 · 2023: 84 · 2022: 78 · 2021: 122 · 2020: 127 · 2019: 104 · 2018: 126 · 2017: 128 · 2016: 118 · 2015: 107 · 2014: 134 · 2013: 124 · 2012: 120
- FWCI
- 48.26
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Howard Hughes Medical Institute
- National Institute of Dental and Craniofacial Research (R01DE012998, DE16523, DE12998, R01DE016523)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Physical Sciences › Chemistry › Organic Chemistry › Photopolymerization techniques and applications
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Keywords
- photodegradable hydrogels, poly(ethylene glycol) hydrogels, dynamic hydrogels, cell migration, chondrogenic differentiation, stem cells, drug carriers, tissue engineering, encapsulated cells
- MeSH terms
- Acrylates, Cell Differentiation, Cell Movement, Cell Survival, Cross-Linking Reagents, Humans, Light, Oligopeptides, Photochemistry, Photolysis, Polyethylene Glycols, Polymers, Chondrocytes, Hydrogels, Chondrogenesis, Collagen Type II, Cell Line, Tumor, Mesenchymal Stem Cells
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