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Cited by 704

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Effects of arterial versus venous sampling on analysis of glucose kinetics in man

McGuire, E. A., Helderman, J. H., Tobin, J. D., Andres, R., Berman, M.·1976·Journal of Applied Physiology
DOI 10.1152/jappl.1976.41.4.565
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Abstract

A compartmental model is presented to account for transient and steady-state changes in blood glucose concentration which result from transit through the forearm and hand in man. This model permits the inter-conversion of arterial and venous data and the derivation of arterial equivalent total body glucose models from venous data. Data were obtained from subjects in thebasal state following a pulse injection of [1–14C]glucose tracer. An artery, an antecubital vein, and a dorsal vein of a heated hand (68 degrees C environment) were sampled. Blood transit time is shorter 0.3 vs. 1.0 min) and irreversible glucose loss is reduced (1.9 vs. 2.9%) in the heated hand preparation when compared to the antecubital vein preparation. Because of the smaller correction required and the smaller variation among individuals whenheated hand rather than antecubital vein data are obtained, we suggest thatfor analysis of whole-body kinetics such data should be used along with thecompartmental model correction when arterial data cannot be obtained.

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Metadata

Authors
McGuire, E. A., Helderman, J. H., Tobin, J. D., Andres, R., & Berman, M.
Venue
Journal of Applied Physiology
Publisher
American Physiological Society
Published
1976-10-01
Volume
41
Issue
4
Pages
565-573
ISSN
  • 0161-7567 (ISSN-L)
  • 8750-7587
  • 1522-1601
DOI
10.1152/jappl.1976.41.4.565
OpenAlex
W2168588540
Cited by
704
References
1
FWCI
1.91
Type
journal article
Language
en
Open access
closed

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