Effects of Spatial Attention on Contrast Response Functions in Macaque Area V4
Abstract
Previous single-unit studies of visual cortex have reported that spatial attention modulates responses to different orientations and directions proportionally, such that it does not change the width of tuning functions for these properties. Other studies have suggested that spatial attention causes a leftward shift in contrast response functions, such that its effects on responses to stimuli of different contrasts are not proportional. We have further explored the effects of attention on stimulus-response functions by measuring the responses of 131 individual V4 neurons in two monkeys while they did a task that controlled their spatial attention. Each neuron was tested with a set of stimuli that spanned complete ranges of orientation and contrast during different states of attention. Consistent with earlier reports, attention scaled responses to preferred and nonpreferred orientations proportionally. However, we did not find compelling evidence that the effects were best described by a leftward shift of the contrast response function. The modulation of neuronal responses by attention was well described by either a leftward shift or proportional scaling of the contrast response function. Consideration of differences in experimental design and analysis that may have contributed to this discrepancy suggests that it was premature to exclude a proportional scaling of responses to different contrasts by attention in favor of a leftward shift of contrast response functions. The current results reopen the possibility that the effects of attention on stimulus-response functions are well described by a single proportional increase in a neuron's response to all stimuli.
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In non-human primate visual system, visual spatial attention within the receptive field of a recorded neuron enhances both contrast gain and response gain.
“Attentional modulation of neural gain has been particularly well studied in the non-human primate visual system1,42,43, in which visual spatial attention within the receptive field of a recorded neuron enhances both contrast gain (that is, scaling of that neuron’s stimulus-response relationship along the contrast axis)43 and response gain (that is, multiplicative transformation of responses to all”
From Mechanisms underlying gain modulation in the cortex (2020) · cites this paper as [48]
Cites
A Statistical Distribution Function of Wide Applicability
Weibull, W. (1951) · Journal of Applied Mechanics · doi:10.1115/1.4010337 · Cited by 11,646 · see citing works
(1966) · Medical Entomology and Zoology · Cited by 10,293 · see citing works
Selective Attention Gates Visual Processing in the Extrastriate Cortex
Moran, J., & Desimone, R. (1985) · Science · doi:10.1126/science.4023713 · Cited by 2,433 · see citing works
Selective Attention Gates Visual Processing in the Extrastriate Cortex
Moran, J., & Desimone, R. (2003) · The MIT Press eBooks · doi:10.7551/mitpress/2834.003.0024 · Cited by 2,164 · see citing works
Neural mechanisms of spatial selective attention in areas V1, V2, and V4 of macaque visual cortex
Luck, S. J., Chelazzi, L., Hillyard, S. A., & Desimone, R. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.77.1.24 · Cited by 1,615 · see citing works
Feature-based attention influences motion processing gain in macaque visual cortex
Treue, S., & Trujillo, J. C. M. (1999) · Nature · doi:10.1038/21176 · Cited by 1,465 · see citing works
Inferotemporal cortex and object vision
Tanaka, K. (1996) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.19.030196.000545 · Cited by 1,402 · see citing works
Competitive Mechanisms Subserve Attention in Macaque Areas V2 and V4
Reynolds, J. H., Chelazzi, L., & Desimone, R. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-05-01736.1999 · Cited by 1,236 · see citing works
Effects of Attention on Orientation-Tuning Functions of Single Neurons in Macaque Cortical Area V4
McAdams, C. J., & Maunsell, J. H. R. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-01-00431.1999 · Cited by 1,201 · see citing works
Self-citationCarrasco, M., Ling, S., & Read, S. (2004) · Nature Neuroscience · doi:10.1038/nn1194 · Cited by 1,095 · see citing works
Attentional modulation of visual motion processing in cortical areas MT and MST
Treue, S., & Maunsell, J. H. R. (1996) · Nature · doi:10.1038/382539a0 · Cited by 1,025 · see citing works
Self-citationAttention Increases Sensitivity of V4 Neurons
Reynolds, J. H., Pasternak, T., & Desimone, R. (2000) · Neuron · doi:10.1016/s0896-6273(00)81206-4 · Cited by 1,017 · see citing works
Gain Modulation from Background Synaptic Input
Chance, F. S., Abbott, L. F., & Reyes, A. D. (2002) · Neuron · doi:10.1016/s0896-6273(02)00820-6 · Cited by 1,012 · see citing works
The Analysis of Moving Visual Patterns
Movshon, J. A., Adelson, E. H., Gizzi, M. S., & Newsome, W. T. (1985) · Experimental brain research. Supplementum · doi:10.1007/978-3-662-09224-8_7 · Cited by 968 · see citing works
Striate cortex of monkey and cat: contrast response function.
Albrecht, D. G., & Hamilton, D. B. (1982) · Journal of Neurophysiology · doi:10.1152/jn.1982.48.1.217 · Cited by 956 · see citing works
Linearity and Normalization in Simple Cells of the Macaque Primary Visual Cortex
Carandini, M., Heeger, D. J., & Movshon, J. A. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-21-08621.1997 · Cited by 926 · see citing works
Increased Attention Enhances Both Behavioral and Neuronal Performance
Spitzer, H., Desimone, R., & Moran, J. (1988) · Science · doi:10.1126/science.3353728 · Cited by 815 · see citing works
Coding of image contrast in central visual pathways of the macaque monkey
Sclar, G., Maunsell, J. H. R., & Lennie, P. (1990) · Vision Research · doi:10.1016/0042-6989(90)90123-3 · Cited by 663 · see citing works
Self-citationSummation and Division by Neurons in Primate Visual Cortex
Carandini, M., & Heeger, D. J. (1994) · Science · doi:10.1126/science.8191289 · Cited by 649 · see citing works
Contour, color and shape analysis beyond the striate cortex
Desimone, R., Schein, S. J., Moran, J., & Ungerleider, L. G. (1985) · Vision Research · doi:10.1016/0042-6989(85)90069-0 · Cited by 535 · see citing works
Neural correlates of attentive selection for color or luminance in extrastriate area V4
Motter, B. C. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-04-02178.1994 · Cited by 482 · see citing works
Inferior Temporal Cortex: Where Visual Perception Meets Memory
Miyashita, Y. (1993) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.16.030193.001333 · Cited by 446 · see citing works
Motion selectivity and the contrast-response function of simple cells in the visual cortex
Albrecht, D. G., & Geisler, W. S. (1991) · Visual Neuroscience · doi:10.1017/s0952523800010336 · Cited by 433 · see citing works
Attentional Modulation Strength in Cortical Area MT Depends on Stimulus Contrast
Martínez-Trujillo, J., & Treue, S. (2002) · Neuron · doi:10.1016/s0896-6273(02)00778-x · Cited by 402 · see citing works
Salinas, E., & Thier, P. (2000) · Neuron · doi:10.1016/s0896-6273(00)00004-0 · Cited by 400 · see citing works
Treue, S., & Maunsell, J. H. R. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-17-07591.1999 · Cited by 366 · see citing works
Self-citationNeuronal Adaptation to Visual Motion in Area MT of the Macaque
Kohn, A., & Movshon, J. A. (2003) · Neuron · doi:10.1016/s0896-6273(03)00438-0 · Cited by 353 · cited 2× · see citing works
“The horizontal shifts of contrast gain are similar to the changes in the sensitivity of individual neurons in monkey visual cortex seen after contrast adaptation (Allison et al. 1993; Carandini et al. 1997; Kohn and Movshon 2003; Sclar et al. 1989).”
BackgroundAttention to Both Space and Feature Modulates Neuronal Responses in Macaque Area V4
McAdams, C. J., & Maunsell, J. H. R. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.3.1751 · Cited by 343 · see citing works
Self-citationAttentional modulation in visual cortex depends on task timing
Ghose, G. M., & Maunsell, J. H. R. (2002) · Nature · doi:10.1038/nature01057 · Cited by 297 · see citing works
Self-citationEffects of Attention on the Reliability of Individual Neurons in Monkey Visual Cortex
McAdams, C. J., & Maunsell, J. H. R. (1999) · Neuron · doi:10.1016/s0896-6273(01)80034-9 · Cited by 286 · see citing works
Self-citationNeural correlates of feature selective memory and pop-out in extrastriate area V4
Motter, B. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-04-02190.1994 · Cited by 282 · see citing works
Ling, S., & Carrasco, M. (2005) · Vision Research · doi:10.1016/j.visres.2005.05.008 · Cited by 273 · see citing works
Salinas, E., & B, T. J. S. A. (2001) · The Neuroscientist · doi:10.1177/107385840100700512 · Cited by 264 · see citing works
Contrast adaptation in striate cortex of macaque
Sclar, G., Lennie, P., & DePriest, D. D. (1989) · Vision Research · doi:10.1016/0042-6989(89)90087-4 · Cited by 259 · see citing works
The role of attention in visual processing
Maunsell, J. H. R., & Cook, E. P. (2002) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2002.1107 · Cited by 214 · see citing works
Self-citationVisual Cortex Neurons of Monkeys and Cats: Temporal Dynamics of the Contrast Response Function
Albrecht, D. G., Geisler, W. S., Frazor, R. A., & Crane, A. M. (2002) · Journal of Neurophysiology · doi:10.1152/jn.2002.88.2.888 · Cited by 207 · see citing works
A Human Extrastriate Area Functionally Homologous to Macaque V4
Gallant, J. L., Shoup, R. E., & Mazer, J. A. (2000) · Neuron · doi:10.1016/s0896-6273(00)00032-5 · Cited by 205 · see citing works
Dynamics of motion signaling by neurons in macaque area MT
Smith, M. A., Majaj, N. J., & Movshon, J. A. (2005) · Nature Neuroscience · doi:10.1038/nn1382 · Cited by 200 · see citing works
Cook, E. P., & Maunsell, J. H. R. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-05-01994.2002 · Cited by 190 · see citing works
Self-citationEffect of Spatial Attention on the Responses of Area MT Neurons
Seidemann, E., & Newsome, W. T. (1999) · Journal of Neurophysiology · doi:10.1152/jn.1999.81.4.1783 · Cited by 175 · see citing works
Effects of Attention on MT and MST Neuronal Activity During Pursuit Initiation
Recanzone, G. H., & Wurtz, R. H. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.2.777 · Cited by 132 · see citing works
Huang, L., & Dobkins, K. R. (2004) · Vision Research · doi:10.1016/j.visres.2004.10.024 · Cited by 113 · see citing works
Cook, E. P., & Maunsell, J. H. R. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5102-03.2004 · Cited by 87 · see citing works
Self-citationPeaked Encoding of Relative Luminance in Macaque Areas V1 and V2
Peng, X., & Essen, D. C. V. (2004) · Journal of Neurophysiology · doi:10.1152/jn.00793.2004 · Cited by 74 · see citing works
Different attentional resources modulate the gain mechanisms for color and luminance contrast
Morrone, M. C., Denti, V., & Donatella Spinelli, A. (2003) · Vision Research · doi:10.1016/j.visres.2003.10.014 · Cited by 70 · see citing works
Neural Correlates of Contrast Detection at Threshold
Thiele, A., Dobkins, K. R., & Albright, T. D. (2000) · Neuron · doi:10.1016/s0896-6273(00)81207-6 · Cited by 45 · see citing works
The Influence of Sustained Selective Attention on Stimulus Selectivity in Macaque Visual Area MT
Wegener, D., Freiwald, W. A., & Kreiter, A. K. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.1459-04.2004 · Cited by 37 · see citing works
Transfer of contrast sensitivity in linear visual networks
Watson, A. B. (1992) · Visual Neuroscience · doi:10.1017/s0952523800006507 · Cited by 34 · see citing works
Allison, J. D., Casagrande, V. A., DeBruyn, E. J., & Bonds, A. B. (1993) · Visual Neuroscience · doi:10.1017/s0952523800010233 · Cited by 17 · see citing works
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Visual attention: The past 25 years
Carrasco, M. (2011) · Vision Research · doi:10.1016/j.visres.2011.04.012 · Cited by 2,462 · see citing works
How Inhibition Shapes Cortical Activity
Isaacson, J. S., & Scanziani, M. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.027 · Cited by 1,678 · see citing works
The Normalization Model of Attention
Reynolds, J. H., & Heeger, D. J. (2009) · Neuron · doi:10.1016/j.neuron.2009.01.002 · Cited by 1,457 · see citing works
Top-down influences on visual processing
Gilbert, C. D., & Li, W. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3476 · Cited by 1,224 · see citing works
Attention improves performance primarily by reducing interneuronal correlations
Cohen, M. R., & Maunsell, J. H. R. (2009) · Nature Neuroscience · doi:10.1038/nn.2439 · Cited by 1,126 · see citing works
Self-citationCortical interneurons that specialize in disinhibitory control
Pi, H.-J., Hangya, B., Kvitsiani, D., Sanders, J. I., Huang, Z. J., & Kepecs, A. (2013) · Nature · doi:10.1038/nature12676 · Cited by 1,136 · see citing works
Fundamental Components of Attention
Knudsen, E. I. (2007) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.30.051606.094256 · Cited by 1,020 · see citing works
Expectation (and attention) in visual cognition
Summerfield, C., & Egner, T. (2009) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2009.06.003 · Cited by 950 · see citing works
Brain States: Top-Down Influences in Sensory Processing
Gilbert, C. D., & Sigman, M. (2007) · Neuron · doi:10.1016/j.neuron.2007.05.019 · Cited by 936 · see citing works
Differential attention-dependent response modulation across cell classes in macaque visual area V4
Mitchell, J. F., Sundberg, K. A., & Reynolds, J. H. (2007) · Neuron · doi:10.1016/j.neuron.2007.06.018 · Cited by 665 · see citing works
Fast modulation of visual perception by basal forebrain cholinergic neurons
Pinto, L., Goard, M. J., Estandian, D., Xu, M., Kwan, A. C., Lee, S.-H., Harrison, T. C., Feng, G., & Dan, Y. (2013) · Nature Neuroscience · doi:10.1038/nn.3552 · Cited by 529 · see citing works
Divisive Normalization in Olfactory Population Codes
Olsen, S. R., Bhandawat, V., & Wilson, R. I. (2010) · Neuron · doi:10.1016/j.neuron.2010.04.009 · Cited by 500 · see citing works
Neural Circuitry of Reward Prediction Error
Watabe-Uchida, M., Eshel, N., & Uchida, N. (2017) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-072116-031109 · Cited by 437 · see citing works
Rapid Neocortical Dynamics: Cellular and Network Mechanisms
Haider, B., & McCormick, D. A. (2009) · Neuron · doi:10.1016/j.neuron.2009.04.008 · Cited by 441 · see citing works
Cortical Enlightenment: Are Attentional Gamma Oscillations Driven by ING or PING?
Tiesinga, P. H. E., & B, T. J. S. A. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.009 · Cited by 421 · see citing works
Feature-Based Attentional Modulations in the Absence of Direct Visual Stimulation
Serences, J. T., & Boynton, G. M. (2007) · Neuron · doi:10.1016/j.neuron.2007.06.015 · Cited by 395 · see citing works
Expectation and Surprise Determine Neural Population Responses in the Ventral Visual Stream
Egner, T., Monti, J. M., & Summerfield, C. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.2770-10.2010 · Cited by 350 · see citing works
From Behavior to Neural Dynamics: An Integrated Theory of Attention
Buschman, T. J., & Kästner, S. (2015) · Neuron · doi:10.1016/j.neuron.2015.09.017 · Cited by 363 · see citing works
Thiele, A., & Bellgrove, M. A. (2018) · Neuron · doi:10.1016/j.neuron.2018.01.008 · Cited by 350 · see citing works
When size matters: attention affects performance by contrast or response gain
Herrmann, K., Montaser‐Kouhsari, L., Carrasco, M., & Heeger, D. J. (2010) · Nature Neuroscience · doi:10.1038/nn.2669 · Cited by 329 · see citing works
Gain Modulation by Nicotine in Macaque V1
Disney, A. A., Aoki, C., & Hawken, M. J. (2007) · Neuron · doi:10.1016/j.neuron.2007.09.034 · Cited by 331 · see citing works
Neuronal Mechanisms of Visual Attention
Maunsell, J. H. R. (2015) · Annual Review of Vision Science · doi:10.1146/annurev-vision-082114-035431 · Cited by 332 · see citing works
Self-citationBottom-Up Dependent Gating of Frontal Signals in Early Visual Cortex
Ekstrom, L. B., Roelfsema, P. R., Arsenault, J. T., Bonmassar, G., & Vanduffel, W. (2008) · Science · doi:10.1126/science.1153276 · Cited by 329 · see citing works
Statistical learning of visual transitions in monkey inferotemporal cortex
Meyer, T., & Olson, C. R. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1112895108 · Cited by 325 · see citing works
Mechanisms underlying gain modulation in the cortex
Ferguson, K. A., & Cardin, J. A. (2020) · Nature Reviews Neuroscience · doi:10.1038/s41583-019-0253-y · Cited by 327 · see citing works
Lovejoy, L. P., & Krauzlis, R. J. (2009) · Nature Neuroscience · doi:10.1038/nn.2470 · Cited by 304 · see citing works
Attentional enhancement of spatial resolution: linking behavioural and neurophysiological evidence
Anton-Erxleben, K., & Carrasco, M. (2013) · Nature reviews. Neuroscience · doi:10.1038/nrn3443 · Cited by 277 · see citing works
The Slow Oscillation in Cortical and Thalamic Networks: Mechanisms and Functions
Neske, G. T. (2016) · Frontiers in Neural Circuits · doi:10.3389/fncir.2015.00088 · Cited by 283 · see citing works
Attention induces synchronization-based response gain in steady-state visual evoked potentials
Kim, Y. J., Grabowecky, M., Paller, K. A., Muthu, K., & Suzuki, S. (2006) · Nature Neuroscience · doi:10.1038/nn1821 · Cited by 261 · see citing works
A Normalization Model of Attentional Modulation of Single Unit Responses
Lee, J., & Maunsell, J. H. R. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004651 · Cited by 257 · see citing works
Self-citationPredictive coding as a model of biased competition in visual attention
Spratling, M. (2008) · Vision Research · doi:10.1016/j.visres.2008.03.009 · Cited by 240 · see citing works
The Nature of Shared Cortical Variability
Lin, I.-C., Okun, M., Carandini, M., & Harris, K. D. (2015) · Neuron · doi:10.1016/j.neuron.2015.06.035 · Cited by 223 · see citing works
Distributed and Mixed Information in Monosynaptic Inputs to Dopamine Neurons
Tian, J., Huang, R., Cohen, J. Y., Osakada, F., Kobak, D., Machens, C. K., Callaway, E. M., Uchida, N., & Watabe-Uchida, M. (2016) · Neuron · doi:10.1016/j.neuron.2016.08.018 · Cited by 224 · see citing works
The neural basis of visual attention
Bisley, J. W. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.192666 · Cited by 215 · see citing works
Attention stabilizes the shared gain of V4 populations
Rabinowitz, N. C., Goris, R. L., Cohen, M., & Simoncelli, E. P. (2015) · eLife · doi:10.7554/elife.08998 · Cited by 194 · see citing works
The Effect of Spatial Attention on Contrast Response Functions in Human Visual Cortex: Figure 1.
Buračas, G. T., & Boynton, G. M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3162-06.2007 · Cited by 189 · see citing works
Attentional Enhancement via Selection and Pooling of Early Sensory Responses in Human Visual Cortex
Pestilli, F., Carrasco, M., Heeger, D. J., & Gardner, J. L. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.025 · Cited by 190 · see citing works
Tracking the allocation of attention using human pupillary oscillations
Naber, M., Alvarez, G. A., & Nakayama, K. (2013) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00919 · Cited by 188 · see citing works
Attention to Stimulus Features Shifts Spectral Tuning of V4 Neurons during Natural Vision
David, S. V., Hayden, B. Y., Mazer, J. A., & Gallant, J. L. (2008) · Neuron · doi:10.1016/j.neuron.2008.07.001 · Cited by 186 · see citing works
How spatial and feature-based attention affect the gain and tuning of population responses
Ling, S., Liu, T., & Carrasco, M. (2008) · Vision Research · doi:10.1016/j.visres.2008.05.025 · Cited by 178 · see citing works
The significance of microsaccades for vision and oculomotor control
Collewijn, H., & Kowler, E. (2008) · Journal of Vision · doi:10.1167/8.14.20 · Cited by 173 · see citing works
Womelsdorf, T., Anton-Erxleben, K., & Treue, S. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.4030-07.2008 · Cited by 163 · see citing works
Spatial Attention Modulates Center-Surround Interactions in Macaque Visual Area V4
Sundberg, K. A., Mitchell, J. F., & Reynolds, J. H. (2009) · Neuron · doi:10.1016/j.neuron.2009.02.023 · Cited by 157 · see citing works
Perceptual Learning Improves Contrast Sensitivity of V1 Neurons in Cats
Hua, T., Bao, P., Huang, C., Wang, Z., Xu, J., Zhou, Y., & Lu, Z. (2010) · Current Biology · doi:10.1016/j.cub.2010.03.066 · Cited by 156 · see citing works
Knowledge as Process: Contextually Cued Attention and Early Word Learning
Smith, L. B., Colunga, E., & Yoshida, H. (2010) · Cognitive Science · doi:10.1111/j.1551-6709.2010.01130.x · Cited by 142 · see citing works
Level Invariant Representation of Sounds by Populations of Neurons in Primary Auditory Cortex
Sadagopan, S., & Wang, X. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2743-07.2008 · Cited by 142 · see citing works
Enhancement of visual responsiveness by spontaneous local network activity in vivo
Haider, B., Duque, A., Hasenstaub, A. R., Yu, Y., & McCormick, D. A. (2007) · Journal of Neurophysiology · doi:10.1152/jn.01114.2006 · Cited by 130 · see citing works
Attention alters spatial integration in macaque V1 in an eccentricity-dependent manner
Roberts, M. J., Delicato, L. S., Herrero, J. L., Gieselmann, M. A., & Thiele, A. (2007) · Nature Neuroscience · doi:10.1038/nn1967 · Cited by 131 · see citing works
A framework for describing the effects of attention on visual responses
Boynton, G. M. (2008) · Vision Research · doi:10.1016/j.visres.2008.11.001 · Cited by 131 · see citing works
Attention Reshapes Center-Surround Receptive Field Structure in Macaque Cortical Area MT
Anton-Erxleben, K., Stephan, V., & Treue, S. (2009) · Cerebral Cortex · doi:10.1093/cercor/bhp002 · Cited by 126 · see citing works
How do attention and adaptation affect contrast sensitivity?
Pestilli, F., Viera, G., & Carrasco, M. (2007) · Journal of Vision · doi:10.1167/7.7.9 · Cited by 130 · see citing works
Serences, J. T., Saproo, S., Scolari, M., Ho, T. C., & Muftuler, L. T. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.07.043 · Cited by 125 · see citing works
Early recurrent feedback facilitates visual object recognition under challenging conditions
Wyatte, D., Jilk, D. J., & O’Reilly, R. C. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.00674 · Cited by 128 · see citing works
How visual spatial attention alters perception
Carrasco, M. (2018) · Cognitive Processing · doi:10.1007/s10339-018-0883-4 · Cited by 126 · see citing works
Li, X., Lu, Z., Tjan, B. S., Dosher, B. A., & Chu, W. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0801390105 · Cited by 122 · see citing works
Attention Is Amplification, Not Selection
Fazekas, P., & Nánay, B. (2018) · The British Journal for the Philosophy of Science · doi:10.1093/bjps/axy065 · Cited by 121 · see citing works
Wyatte, D., Curran, T., & O’Reilly, R. C. (2012) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00282 · Cited by 121 · see citing works
The primate model for understanding and restoring vision
Picaud, S. A., Dalkara, D., Marazova, K., Goureau, O., Roska, B., & Sahel, J. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1902292116 · Cited by 114 · see citing works
The Peri-Saccadic Perception of Objects and Space
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The role of feedback in visual masking and visual processing
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Tuned Normalization Explains the Size of Attention Modulations
Ni, A. M., Ray, S., & Maunsell, J. H. R. (2012) · Neuron · doi:10.1016/j.neuron.2012.01.006 · Cited by 109 · see citing works
Self-citationThe effects of spatial attention in early human visual cortex are stimulus independent
Murray, S. O. (2008) · Journal of Vision · doi:10.1167/8.10.2 · Cited by 107 · see citing works
Learning Enhances Sensory Processing in Mouse V1 before Improving Behavior
Jurjut, O., Georgieva, P., Busse, L., & Katzner, S. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.3485-16.2017 · Cited by 99 · see citing works
Spatial Attention and the Latency of Neuronal Responses in Macaque Area V4
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Pestilli, F., Ling, S., & Carrasco, M. (2008) · Vision Research · doi:10.1016/j.visres.2008.09.018 · Cited by 95 · see citing works
Differential impact of endogenous and exogenous attention on activity in human visual cortex
Dugué, L., Merriam, E. P., Heeger, D. J., & Carrasco, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-78172-x · Cited by 98 · see citing works
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Marino, R. A., Levy, R., Boehnke, S. E., White, B. J., Itti, L., & Munoz, D. P. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08079.x · Cited by 91 · see citing works
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Cardin, J. A., Palmer, L. A., & Contreras, D. (2008) · Neuron · doi:10.1016/j.neuron.2008.05.002 · Cited by 90 · see citing works
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Itthipuripat, S., Garcia, J. O., Rungratsameetaweemana, N., Sprague, T. C., & Serences, J. T. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.3943-13.2014 · Cited by 89 · see citing works
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Ekstrom, L. B., Roelfsema, P. R., Arsenault, J. T., Kolster, H., & Vanduffel, W. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.0673-09.2009 · Cited by 83 · see citing works
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Deco, G., & Thiele, A. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06833.x · Cited by 85 · see citing works
Zhaoping, L. (2014) · doi:10.1093/acprof:oso/9780199564668.001.0001 · Cited by 158 · see citing works
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Ikkai, A., Dandekar, S., & Curtis, C. E. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154796 · Cited by 74 · see citing works
Long-range neural coupling through synchronization with attention
Gregoriou, G. G., Gotts, S. J., Zhou, H., & Desimone, R. (2009) · Progress in brain research · doi:10.1016/s0079-6123(09)17603-3 · Cited by 82 · see citing works
Attentional modulation of neuronal variability in circuit models of cortex
Kanashiro, T., Ocker, G. K., Cohen, M. R., & Doiron, B. (2017) · eLife · doi:10.7554/elife.23978 · Cited by 81 · see citing works
Feature-based attention enhances performance by increasing response gain
Herrmann, K., Heeger, D. J., & Carrasco, M. (2012) · Vision Research · doi:10.1016/j.visres.2012.04.016 · Cited by 78 · see citing works
Sylvester, C. M., Shulman, G. L., Jack, A. I., & Corbetta, M. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1141-09.2009 · Cited by 76 · see citing works
Cholinergic modulation of response gain in the primary visual cortex of the macaque
Soma, S., Shimegi, S., Osaki, H., & Sato, H. (2012) · Journal of Neurophysiology · doi:10.1152/jn.00330.2011 · Cited by 75 · see citing works
Itthipuripat, S., Ester, E. F., Deering, S., & Serences, J. T. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.2277-14.2014 · Cited by 68 · see citing works
Statistical decision theory to relate neurons to behavior in the study of covert visual attention
Eckstein, M. P., Peterson, M., Pham, B. T., & Droll, J. A. (2009) · Vision Research · doi:10.1016/j.visres.2008.12.008 · Cited by 74 · see citing works
Mysore, S. P., & Knudsen, E. I. (2012) · Neuron · doi:10.1016/j.neuron.2011.10.037 · Cited by 71 · see citing works
Gain Modulation of Neuronal Responses by Subtractive and Divisive Mechanisms of Inhibition
Ayaz, A., & Chance, F. S. (2008) · Journal of Neurophysiology · doi:10.1152/jn.90547.2008 · Cited by 72 · see citing works
The role of early visual cortex in visual short-term memory and visual attention
Offen, S., Schluppeck, D., & Heeger, D. J. (2008) · Vision Research · doi:10.1016/j.visres.2007.12.022 · Cited by 69 · see citing works
Geng, J. J., & DiQuattro, N. E. (2010) · Journal of Vision · doi:10.1167/10.6.5 · Cited by 71 · see citing works
Ferro, D., van Kempen, J., Boyd, M., Panzeri, S., & Thiele, A. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2022097118 · Cited by 75 · see citing works
Evaluating comparative and equality judgments in contrast perception: Attention alters appearance
Anton-Erxleben, K., Abrams, J., & Carrasco, M. (2010) · Journal of Vision · doi:10.1167/10.11.6 · Cited by 70 · see citing works
Reward expectation differentially modulates attentional behavior and activity in visual area V4
Baruni, J., Lau, B., & Salzman, C. D. (2015) · Nature Neuroscience · doi:10.1038/nn.4141 · Cited by 68 · see citing works
Both a Gauge and a Filter: Cognitive Modulations of Pupil Size
Ebitz, R. B., & Moore, T. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2018.01190 · Cited by 69 · see citing works
Carrasco, M., Fuller, S., & Ling, S. (2008) · Perception & Psychophysics · doi:10.3758/pp.70.7.1151 · Cited by 67 · see citing works
Separable Codes for Attention and Luminance Contrast in the Primary Visual Cortex
Pooresmaeili, A., Poort, J., Thiele, A., & Roelfsema, P. R. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1388-10.2010 · Cited by 68 · see citing works
Effects of Prior Information and Reward on Oculomotor and Perceptual Choices
Liston, D. B., & Stone, L. S. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3120-08.2008 · Cited by 66 · see citing works
Distinct Mechanisms for Top-Down Control of Neural Gain and Sensitivity in the Owl Optic Tectum
Winkowski, D. E., & Knudsen, E. I. (2008) · Neuron · doi:10.1016/j.neuron.2008.09.013 · Cited by 66 · see citing works
- Authors
- Williford, T., & Maunsell, J. H. R.
- Affiliations
- Howard Hughes Medical Institute (US)
- ORCID
- Maunsell, John H. R.
- Venue
- Journal of Neurophysiology
- Publisher
- American Physiological Society
- Published
- 2006-07
- Volume
- 96
- Issue
- 1
- Pages
- 40-54
- ISSN
- 0022-3077 (ISSN-L)
- 1522-1598
- OpenAlex
- W2092212529
- Cited by
- 353
- References
- 49
- Citations by year
- 2026: 5 · 2025: 12 · 2024: 17 · 2023: 14 · 2022: 10 · 2021: 22 · 2020: 9 · 2019: 16 · 2018: 11 · 2017: 15 · 2016: 18 · 2015: 16 · 2014: 28 · 2013: 22 · 2012: 18
- FWCI
- 13.77
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neurophysiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Visual Attention and Saliency Detection
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Multisensory perception and integration
- Keywords
- spatial attention, contrast response function, area V4, macaque visual cortex, orientation tuning, proportional scaling, leftward shift, single-unit responses, stimulus-response function, attentional modulation
- MeSH terms
- Animals, Attention, Evoked Potentials, Visual, Macaca mulatta, Male, Neurons, Afferent, Orientation, Pattern Recognition, Visual, Psychophysiology, Space Perception, Visual Cortex, Contrast Sensitivity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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