The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Involvement of Adult Hippocampal Neurogenesis in Learning and Forgetting
Open accessAbstract
Adult hippocampal neurogenesis is a process involving the continuous generation of newborn neurons in the hippocampus of adult animals. Mounting evidence has suggested that hippocampal neurogenesis contributes to some forms of hippocampus-dependent learning and memory; however, the detailed mechanism concerning how this small number of newborn neurons could affect learning and memory remains unclear. In this review, we discuss the relationship between adult-born neurons and learning and memory, with a highlight on recently discovered potential roles of neurogenesis in pattern separation and forgetting.
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Citations
Cites
Neural networks and physical systems with emergent collective computational abilities.
Hopfield, J. J. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.8.2554 · Cited by 19,270
Running enhances neurogenesis, learning, and long-term potentiation in mice
van Praag, H., Christie, B. R., Sejnowski, T. J., & Gage, F. H. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.23.13427 · Cited by 2,904
Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions
Ming, G.-L., & Song, H. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.001 · Cited by 2,651
Modality-Specific Retrograde Amnesia of Fear
Kim, J. J., & Fanselow, M. S. (1992) · Science · doi:10.1126/science.1585183 · Cited by 2,483
New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?
Deng, W., Aimone, J. B., & Gage, F. H. (2010) · Nature reviews. Neuroscience · doi:10.1038/nrn2822 · Cited by 2,120
Pattern Separation in the Dentate Gyrus and CA3 of the Hippocampus
Leutgeb, J. K., Leutgeb, S., Moser, M.-B., & Moser, E. I. (2007) · Science · doi:10.1126/science.1135801 · Cited by 1,601
Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation
Sahay, A., Scobie, K. N., Hill, A. S., O'Carroll, C. M., Kheirbek, M. A., Burghardt, N. S., Fenton, A. A., Dranovsky, A., & Hen, R. (2011) · Nature · doi:10.1038/nature09817 · Cited by 1,567
Pattern separation in the hippocampus
Yassa, M. A., & Stark, C. E. L. (2011) · Trends in Neurosciences · doi:10.1016/j.tins.2011.06.006 · Cited by 1,544
Adult hippocampal neurogenesis buffers stress responses and depressive behaviour
Snyder, J. S., Soumier, A., Brewer, M., Pickel, J., & Cameron, H. A. (2011) · Nature · doi:10.1038/nature10287 · Cited by 1,473
Hippocampal synaptic enhancement and information storage within a distributed memory system
McNaughton, B. L., & Morris, R. G. M. (1987) · Trends in Neurosciences · doi:10.1016/0166-2236(87)90011-7 · Cited by 1,304
Lemaire, V., Koehl, M., Le Moal, M., & Abrous, D. N. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.20.11032 · Cited by 1,044 · cited 1×
“reference memory in the MWM task [92], all of which”
BackgroundKee, N., Teixeira, C. M., Wang, A. H., & Frankland, P. W. (2007) · Nature Neuroscience · doi:10.1038/nn1847 · Cited by 875
VEGF links hippocampal activity with neurogenesis, learning and memory
Cao, L., Jiao, X., Zuzga, D. S., Liu, Y., Fong, D. M., Young, D., & During, M. J. (2004) · Nature Genetics · doi:10.1038/ng1395 · Cited by 850
Neuronal Networks of the Hippocampus
Traub, R. D., & Miles, R. (1991) · doi:10.1017/cbo9780511895401 · Cited by 802
Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy
Akers, K. G., Martinez-Canabal, A., Restivo, L., Yiu, A. P., De Cristofaro, A., Hsiang, H.-L. (., Wheeler, A. L., Guskjolen, A., Niibori, Y., Shoji, H., et al. (2014) · Science · doi:10.1126/science.1248903 · Cited by 761
Neurons born in the adult dentate gyrus form functional synapses with target cells
Toni, N., Laplagne, D. A., Zhao, C., Lombardi, G., Ribak, C. E., Gage, F. H., & Schinder, A. F. (2008) · Nature Neuroscience · doi:10.1038/nn.2156 · Cited by 741
Mirescu, C., & Gould, E. (2006) · Hippocampus · doi:10.1002/hipo.20155 · Cited by 701 · cited 1×
“Levels of neurogenesis in the DG can be modulated by various factors, among which the most frequently employed strategies include environment enrichment [72] and physical exercise as positive regulators [73] and environmental stressors such as chronic unpredictable stress as potent negative regulators [74].”
BackgroundAimone, J. B., Deng, W., & Gage, F. H. (2011) · Neuron · doi:10.1016/j.neuron.2011.05.010 · Cited by 663 · cited 1×
“With the aforementioned features of the DG, the patternseparation function of adult-born hippocampal neurons has emerged as the neurobiological basis mediating the influence of adult hippocampal neurogenesis on learning and memory [18, 127].”
BackgroundMurine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years
Knoth, R., Singec, I., Ditter, M., Pantazis, G., Capetian, P., Meyer, R. P., Horvat, V., Volk, B., & Kempermann, G. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008809 · Cited by 650
Neurogenesis and Exercise: Past and Future Directions
van Praag, H. (2008) · NeuroMolecular Medicine · doi:10.1007/s12017-008-8028-z · Cited by 645
Adult-Generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies
Garthe, A., Behr, J., & Kempermann, G. (2009) · PLoS ONE · doi:10.1371/journal.pone.0005464 · Cited by 597
Synapse formation on neurons born in the adult hippocampus
Toni, N., Teng, E. M., Bushong, E. A., Aimone, J. B., Zhao, C., Consiglio, A., van Praag, H., Martone, M. E., Ellisman, M. H., & Gage, F. H. (2007) · Nature Neuroscience · doi:10.1038/nn1908 · Cited by 579
Deng, W., Saxe, M. D., Gallina, I. S., & Gage, F. H. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3362-09.2009 · Cited by 493
Single granule cells reliably discharge targets in the hippocampal CA3 network in vivo
Henze, D. A., Wittner, L., & Buzsáki, G. (2002) · Nature Neuroscience · doi:10.1038/nn887 · Cited by 480
Vazdarjanova, A., & Guzowski, J. F. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.0350-04.2004 · Cited by 465
The exercise-induced expression of BDNF within the hippocampus varies across life-span
Adlard, P. A., Perreau, V. M., & Cotman, C. W. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.05.006 · Cited by 260
Pattern separation, pattern completion, and new neuronal codes within a continuous CA3 map
Leutgeb, S., & Leutgeb, J. K. (2007) · Learning & Memory · doi:10.1101/lm.703907 · Cited by 234
BDNF in the dentate gyrus is required for consolidation of “pattern-separated” memories.
Bekinschtein, P., Kent, B. A., Oomen, C. A., Clemenson, G. D., Gage, F. H., Saksida, L. M., & Bussey, T. J. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.09.027 · Cited by 124
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Understanding the Role of T Cells in CNS Homeostasis
Ellwardt, E., Walsh, J. T., Kipnis, J., & Zipp, F. (2016) · Trends in Immunology · doi:10.1016/j.it.2015.12.008 · Cited by 156
Functional and Structural Benefits Induced by Omega-3 Polyunsaturated Fatty Acids During Aging
Cutuli, D. (2017) · Current Neuropharmacology · doi:10.2174/1570159x14666160614091311 · Cited by 139
Bassani, T. B., Turnes, J. M., Moura, E. L. R., Bonato, J. M., Cóppola-Segovia, V., Zanata, S. M., Oliveira, R. M. M. W., & Vital, M. A. B. F. (2017) · Behavioural Brain Research · doi:10.1016/j.bbr.2017.08.014 · Cited by 134
Traumatic brain injury and hippocampal neurogenesis: Functional implications
Redell, J. B., Maynard, M. E., Underwood, E. L., Vita, S. M., Dash, P. K., & Kobori, N. (2020) · Experimental Neurology · doi:10.1016/j.expneurol.2020.113372 · Cited by 75
Patten, A. R., Yau, S. Y., Fontaine, C. J., Meconi, A., Wortman, R. C., & Christie, B. R. (2015) · Brain Plasticity · doi:10.3233/bpl-150016 · Cited by 64
Self-citation
Metadata
- Authors
- Yau, S.-Y., Li, A., & So, K.-F.
- Venue
- Neural Plasticity
- Publisher
- Hindawi Limited
- Published
- 2015
- Volume
- 2015
- Pages
- 1-13
- ISSN
- 1687-5443 (ISSN-L)
- 2090-5904
- OpenAlex
- W1503343518
- Cited by
- 165
- References
- 28
- FWCI
- 6.80
- Type
- journal article
- Language
- en
- Open access
- gold
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