The metabolic phenotype in obesity: Fat mass, body fat distribution, and adipose tissue function

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Items 101–200 of 414

1. A new framework for the diagnosis, staging and management of obesity in adults
   Busetto, Luca, Dicker, Dror, Frühbeck, Gema, Halford, Jason C. G., Sbraccia, Paolo, Yumuk, Volkan, Goossens, Gijs H. · 2024 · Nature Medicine
2. Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease, and cancer: systematic review and meta-analysis
   Ma, Chenhan, Avenell, Alison, Bolland, Mark, Hudson, Jemma, Stewart, Fiona, Robertson, Clare, Sharma, Pawana, Fraser, Cynthia, MacLennan, Graeme · 2017 · BMJ
3. Obesity and related consequences to ageing
   Jura, Magdalena, Kozak, Leslie.P. · 2016 · AGE
4. Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis
   Green, Courtney R, Wallace, Martina, Divakaruni, Ajit S, Phillips, Susan A, Murphy, Anne N, Ciaraldi, Theodore P, Metallo, Christian M · 2016 · Nature Chemical Biology
5. Metabolically healthy versus metabolically unhealthy obesity
   Iacobini, Carla, Pugliese, Giuseppe, Blasetti Fantauzzi, Claudia, Federici, Massimo, Menini, Stefano · 2019 · Metabolism
6. Increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals
   Boden, Guenther, Duan, Xunbao, Homko, Carol, Molina, Ezequiel J., Song, WeiWei, Perez, Oscar, Cheung, Peter, Merali, Salim · 2008 · Diabetes
7. The role of adipokines in health and disease
   Clemente-Suárez, Vicente Javier, Redondo-Flórez, Laura, Beltrán-Velasco, Ana Isabel, Martín-Rodríguez, Alexandra, Martínez-Guardado, Ismael, Navarro-Jiménez, Eduardo, Laborde-Cárdenas, Carmen Cecilia, Tornero-Aguilera, José Francisco · 2023 · Biomedicines
8. Age-related changes in glucose metabolism, hyperglycemia, and cardiovascular risk
   Chia, Chee W., Egan, Josephine M., Ferrucci, Luigi · 2018 · Circulation Research
9. A review of current trends with type 2 diabetes epidemiology, aetiology, pathogenesis, treatments and future perspectives
   Reed, Josh, Bain, Stephen, Kanamarlapudi, Venkateswarlu · 2021 · Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
10. Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues
    Pellegrinelli, Vanessa, Carobbio, Stefania, Vidal-Puig, Antonio · 2016 · Diabetologia
11. Obesity and the risk of cardiometabolic diseases
    Valenzuela, Pedro L., Carrera-Bastos, Pedro, Castillo-García, Adrián, Lieberman, Daniel E., Santos-Lozano, Alejandro, Lucia, Alejandro · 2023 · Nature Reviews Cardiology
12. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women
    Yoshino, Mihoko, Yoshino, Jun, Kayser, Brandon D., Patti, Gary J., Franczyk, Michael P., Mills, Kathryn F., Sindelar, Miriam, Pietka, Terri, Patterson, Bruce W., Imai, Shin-Ichiro et al. · 2021 · Science
13. Association of body mass index with health care expenditures in the united states by age and sex
    Ward, Zachary J., Bleich, Sara N., Long, Michael W., Gortmaker, Steven L. · 2021 · PLOS ONE
14. Major microbiota dysbiosis in severe obesity: fate after bariatric surgery
    Aron-Wisnewsky, Judith, Prifti, Edi, Belda, Eugeni, Ichou, Farid, Kayser, Brandon D, Dao, Maria Carlota, Verger, Eric O, Hedjazi, Lyamine, Bouillot, Jean-Luc, Chevallier, Jean-Marc et al. · 2019 · Gut
15. Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation
    Spencer, Michael, Yao-Borengasser, Aiwei, Unal, Resat, Rasouli, Neda, Gurley, Catherine M., Zhu, Beibei, Peterson, Charlotte A., Kern, Philip A. · 2010 · American Journal of Physiology-Endocrinology and Metabolism
16. Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice
    Masuzaki, Hiroaki, Yamamoto, Hiroshi, Kenyon, Christopher J., Elmquist, Joel K., Morton, Nicholas M., Paterson, Janice M., Shinyama, Hiroshi, Sharp, Matthew G.F., Fleming, Stewart, Mullins, John J. et al. · 2003 · Journal of Clinical Investigation
17. Social jetlag, obesity and metabolic disorder: investigation in a cohort study
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18. Framework to construct and interpret latent class trajectory modelling
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19. Ovarian hormones and obesity
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20. How May GIP Enhance the Therapeutic Efficacy of GLP-1?
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21. Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men
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22. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity
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23. Tongue Fat and its Relationship to Obstructive Sleep Apnea
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24. An immune origin of type 2 diabetes?
    Kolb, H., Mandrup-Poulsen, T. · 2005 · Diabetologia
25. Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat
    Dodd, Garron T., Decherf, Stephanie, Loh, Kim, Simonds, Stephanie E., Wiede, Florian, Balland, Eglantine, Merry, Troy L., Münzberg, Heike, Zhang, Zhong-Yin, Kahn, Barbara B. et al. · 2015 · Cell
26. Using the Edmonton Obesity Staging System to predict mortality in a population-representative cohort of people with overweight and obesity.
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27. One-Year Treatment With Exenatide Improves β-Cell Function, Compared With Insulin Glargine, in Metformin-Treated Type 2 Diabetic Patients
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28. Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans
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29. Polyunsaturated fatty acids of marine origin upregulate mitochondrial biogenesis and induce β-oxidation in white fat
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30. Roles of diacylglycerols and ceramides in hepatic insulin resistance
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31. Aging, obesity, and inflammatory age-related diseases
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32. Long-term pharmacotherapy for obesity and overweight
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33. Genetic Association of Waist-to-Hip Ratio With Cardiometabolic Traits, Type 2 Diabetes, and Coronary Heart Disease
    Emdin, Connor A., Khera, Amit V., Natarajan, Pradeep, Klarin, Derek, Zekavat, Seyedeh M., Hsiao, Allan J., Kathiresan, Sekar · 2017 · JAMA
34. Childhood obesity and risk of the adult metabolic syndrome: a systematic review
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35. Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis
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36. Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis
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37. Body Mass Index and Adverse Cardiovascular Outcomes in Heart Failure Patients With Preserved Ejection Fraction: Results From the Irbesartan in Heart Failure With Preserved Ejection Fraction (I-PRESERVE) Trial
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38. Physical activity and all-cause mortality across levels of overall and abdominal adiposity in European men and women: the European Prospective Investigation into Cancer and Nutrition Study (EPIC)
    Ekelund, Ulf, Ward, Heather A, Norat, Teresa, Luan, Jian’an, May, Anne M, Weiderpass, Elisabete, Sharp, Stephen J, Overvad, Kim, Østergaard, Jane Nautrup, Tjønneland, Anne et al. · 2015 · The American Journal of Clinical Nutrition
39. Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome
    Kawano, Yoshinaga, Edwards, Madeline, Huang, Yiming, Bilate, Angelina M., Araujo, Leandro P., Tanoue, Takeshi, Atarashi, Koji, Ladinsky, Mark S., Reiner, Steven L., Wang, Harris H. et al. · 2022 · Cell
40. Association Between Visceral and Subcutaneous Adipose Depots and Incident Cardiovascular Disease Risk Factors
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41. The adipose tissue microenvironment regulates depot-specific adipogenesis in obesity
    Jeffery, Elise, Wing, Allison, Holtrup, Brandon, Sebo, Zachary, Kaplan, Jennifer L., Saavedra-Peña, Rocio, Church, Christopher D., Colman, Laura, Berry, Ryan, Rodeheffer, Matthew S. · 2016 · Cell Metabolism
42. Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitors
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43. Sarcopenia and sarcopenic obesity
    Choi, Kyung Mook · 2016 · The Korean Journal of Internal Medicine
44. Depot-Specific Differences and Insufficient Subcutaneous Adipose Tissue Angiogenesis in Human Obesity
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45. Sarcopenic obesity in older adults: a clinical overview
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46. Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle
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47. The impact of aging on adipose function and adipokine synthesis
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48. FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms
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49. Associations between gender, age and waist circumference
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50. The ABCD of Obesity: An EASO Position Statement on a Diagnostic Term with Clinical and Scientific Implications
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51. Impairment of the glymphatic system after diabetes
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52. (n-3) Fatty Acids Alleviate Adipose Tissue Inflammation and Insulin Resistance: Mechanistic Insights
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53. Indications for Surgery for Obesity and Weight-Related Diseases: Position Statements from the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO)
    De Luca, Maurizio, Angrisani, Luigi, Himpens, Jacques, Busetto, Luca, Scopinaro, Nicola, Weiner, Rudolf, Sartori, Alberto, Stier, Christine, Lakdawala, Muffazal, Bhasker, Aparna G. et al. · 2016 · Obesity Surgery
54. Adipose-resident group 1 innate lymphoid cells promote obesity-associated insulin resistance
    O’Sullivan, Timothy E., Rapp, Moritz, Fan, Xiying, Weizman, Orr-El, Bhardwaj, Priya, Adams, Nicholas M., Walzer, Thierry, Dannenberg, Andrew J., Sun, Joseph C. · 2016 · Immunity
55. Effect of Calorie Restriction with or without Exercise on Body Composition and Fat Distribution
    Redman, Leanne M., Heilbronn, Leonie K., Martin, Corby K., Alfonso, Anthony, Smith, Steven R., Ravussin, Eric, for the Pennington CALERIE Team · 2007 · The Journal of Clinical Endocrinology & Metabolism
56. Prevention of Type 2 Diabetes Mellitus Through Inhibition of the Renin-Angiotensin System
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57. Nutrition and the gut microbiome in the elderly
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58. Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance
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59. Body mass index in midlife and dementia: systematic review and meta-regression analysis of 589,649 men and women followed in longitudinal studies
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60. Hypoxia decreases insulin signaling pathways in adipocytes.
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61. Live strong and prosper: the importance of skeletal muscle strength for healthy ageing
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62. Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty
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63. Osteosarcopenic obesity: the role of bone, muscle, and fat on health
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64. Role of microRNAs in diabetes and its cardiovascular complications
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65. Inter-organ crosstalk during development and progression of type 2 diabetes mellitus
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66. Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training
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67. AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue
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68. Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation
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69. Fatty acid diets: regulation of gut microbiota composition and obesity and its related metabolic dysbiosis
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70. Association of Genetic Variants Related to Gluteofemoral vs Abdominal Fat Distribution With Type 2 Diabetes, Coronary Disease, and Cardiovascular Risk Factors
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71. Sarcopenic obesity: time to meet the challenge
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72. The Differential Roles of T Cells in Non-alcoholic Fatty Liver Disease and Obesity
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73. Common risk factors for major noncommunicable disease, a systematic overview of reviews and commentary: the implied potential for targeted risk reduction
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74. The Role of Oxidative Stress in Skeletal Muscle Myogenesis and Muscle Disease
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75. Critical role of STAT3 in leptin's metabolic actions
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76. Mitochondrial Patch Clamp of Beige Adipocytes Reveals UCP1-Positive and UCP1-Negative Cells Both Exhibiting Futile Creatine Cycling
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77. Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2
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78. Ectopic and Visceral Fat Deposition in Lean and Obese Patients With Type 2 Diabetes
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79. Exercise and nutrition strategies to counteract sarcopenic obesity
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80. ‘Adipaging’: ageing and obesity share biological hallmarks related to a dysfunctional adipose tissue
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81. Fibroblast Growth Factor 21: A Versatile Regulator of Metabolic Homeostasis
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82. Intracrine androgen biosynthesis, metabolism and action revisited
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83. Management of cardiovascular diseases in patients with obesity
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84. Body fat distribution and the risk of incident metabolic syndrome: A longitudinal cohort study
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85. Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men
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86. Risk of knee osteoarthritis with obesity, sarcopenic obesity, and sarcopenia
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87. Human Obesity: A Heritable Neurobehavioral Disorder That Is Highly Sensitive to Environmental Conditions
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88. Mechanisms of weight regain after weight loss — the role of adipose tissue
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89. Site and mechanism of leptin action in a rodent form of congenital lipodystrophy
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90. Mediterranean Diet and Obesity-related Disorders: What is the Evidence?
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91. Sarcopenia, sarcopenic obesity, and functional impairments in older adults: National Health and Nutrition Examination Surveys 1999-2004
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92. Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition
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93. Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity
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94. Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4
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95. Immunologic and endocrine functions of adipose tissue: implications for kidney disease
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96. Nutrition, insulin resistance and dysfunctional adipose tissue determine the different components of metabolic syndrome
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97. Prevalence of Pre-Diabetes across Ethnicities: A Review of Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT) for Classification of Dysglycaemia
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98. The initiation of metabolic inflammation in childhood obesity
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99. Body mass index and all cause mortality in HUNT and UK Biobank studies: linear and non-linear mendelian randomisation analyses
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100. Incretin hormones and type 2 diabetes
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