Cited by 5,784Cardiovascular Health and Risk FactorsHealthcare Systems and Public HealthHealth Promotion and Cardiovascular Prevention

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Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association

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Virani, Salim S., Alonso, Alvaro, Aparicio, Hugo J., Benjamin, Emelia J., Bittencourt, Marcio S., Callaway, Clifton W., Carson, April P., Chamberlain, Alanna M., Cheng, Susan, Delling, Francesca N., Elkind, Mitchell S.V., Evenson, Kelly R., Ferguson, Jane F., Gupta, Deepak K., Khan, Sadiya S., Kissela, Brett M., Knutson, Kristen L., Lee, Chong D., Lewis, Tené T., Liu, Junxiu, Loop, Matthew Shane, Lutsey, Pamela L., Ma, Jun, Mackey, Jason, Martin, Seth S., Matchar, David B., Mussolino, Michael E., Navaneethan, Sankar D., Perak, Amanda Marma, Roth, Gregory A., Samad, Zainab, Satou, Gary M., Schroeder, Emily B., Shah, Svati H., Shay, Christina M., Stokes, Andrew, VanWagner, Lisa B., Wang, Nae-Yuh, Tsao, Connie W., On behalf of the American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee·2021·Circulation

DOI 10.1161/cir.0000000000000950PMC PMC13036842

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Abstract

Background: The American Heart Association, in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, and weight) and health factors (cholesterol, blood pressure, and glucose control) that contribute to cardiovascular health. The Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary heart disease, heart failure, valvular disease, venous disease, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). Methods: The American Heart Association, through its Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States to provide the most current information available in the annual Statistical Update. The 2021 Statistical Update is the product of a full year’s worth of effort by dedicated volunteer clinicians and scientists, committed government professionals, and American Heart Association staff members. This year’s edition includes data on the monitoring and benefits of cardiovascular health in the population, an enhanced focus on social determinants of health, adverse pregnancy outcomes, vascular contributions to brain health, the global burden of cardiovascular disease, and further evidence-based approaches to changing behaviors related to cardiovascular disease. Results: Each of the 27 chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. Conclusions: The Statistical Update represents a critical resource for the lay public, policy makers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.

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Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 2013;368:1279-90.
Estruch, R., Ros, E., Salas-Salvadó, J., Covas, M.-I., Corella, D., Arós, F., Gómez-Gracia, E., Ruiz-Gutiérrez, V., Fiol, M., Lapetra, J., et al. (2018) · New England Journal of Medicine · doi:10.1056/nejmc1806491 · Cited by 1,008
Retracted
RETRACTED: Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality
Banegas, J. R., Ruilope, L. M., de la Sierra, A., Vinyoles, E., Gorostidi, M., de la Cruz, J. J., Ruiz-Hurtado, G., Segura, J., Rodríguez-Artalejo, F., & Williams, B. (2018) · New England Journal of Medicine · doi:10.1056/nejmoa1712231 · Cited by 490
Retracted
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
Vos, T., Lim, S. S., Abbafati, C., Abbas, K. M., Abbasi, M., Abbasifard, M., Abbasi-Kangevari, M., Abbastabar, H., Abd-Allah, F., Abdelalim, A., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30925-9 · Cited by 19,358
Self-citation
Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial
Writing Group for the Women's Health Initiative Investigators (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.3.321 · Cited by 15,889
Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L., Jones, D. W., Materson, B. J., Oparil, S., Wright, J. T., et al. (2003) · Hypertension · doi:10.1161/01.hyp.0000107251.49515.c2 · Cited by 13,271
Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies
(2004) · The Lancet · doi:10.1016/s0140-6736(03)15268-3 · Cited by 12,717
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Yusuf, S., Hawken, S., Ôunpuu, S., Dans, T., Avezum, A., Lanas, F., McQueen, M., Budaj, A., Pais, P., Varigos, J., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17018-9 · Cited by 12,026
The Physical Activity Guidelines for Americans
Piercy, K. L., Troiano, R. P., Ballard, R. M., Carlson, S. A., Fulton, J. E., Galuska, D. A., George, S. M., & Olson, R. D. (2018) · JAMA · doi:10.1001/jama.2018.14854 · Cited by 9,755
Prevalence of Childhood and Adult Obesity in the United States, 2011-2012
Ogden, C. L., Carroll, M. D., Kit, B. K., & Flegal, K. M. (2014) · JAMA · doi:10.1001/jama.2014.732 · Cited by 8,072
IDF Diabetes Atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045
Cho, N. H., Shaw, J. E., Karuranga, S., Huang, Y., da Rocha Fernandes, J. D., Ohlrogge, A. W., & Malanda, B. (2018) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2018.02.023 · Cited by 7,283

Show all 0 references

Research works printed but not linked: 2713

World Health Organization. International Statistical Classification of Diseases and Related Health Problems, 10th Revision. 2008 ed. Geneva, Switzerland: World Health Organization; 2009.
Anderson, RN, Rosenberg, HM. Age standardization of death rates: implementation of the year 2000 standard. Natl Vital Stat Rep. 1998;47:1–16, 20.
10.1016/S0140-6736(20)30752-2 · DOI · Paper page
10.1016/j.pcad.2015.05.003 · DOI
10.1016/j.ahj.2016.02.008 · DOI
10.1161/CIRCHEARTFAILURE.116.003682 · DOI
10.1016/j.amjmed.2015.03.027 · DOI
10.1371/journal.pone.0052771 · DOI
10.1161/JAHA.116.005180 · DOI
10.1093/ajh/hpz057 · DOI
10.1016/j.hlc.2016.02.007 · DOI
10.1016/j.ijcard.2015.03.051 · DOI
10.1016/j.mayocp.2016.01.019 · DOI · Paper page
10.1136/jech-2017-210396 · DOI
10.1016/j.ypmed.2016.12.017 · DOI
10.1111/ene.13056 · DOI
10.1111/1744-7917.12513 · DOI
10.1161/ATVBAHA.118.311821 · DOI
10.3390/ijerph16112028 · DOI
10.1016/j.ijcard.2018.06.037 · DOI
10.1177/0003319718813448 · DOI
10.1016/j.jacc.2010.11.041 · DOI · Paper page
10.1016/j.ijcard.2016.03.210 · DOI
10.1001/jama.2012.339 · DOI · Paper page
10.1161/STROKEAHA.111.000352 · DOI
10.1001/jama.2012.14312 · DOI
10.1016/j.ahj.2014.12.017 · DOI
10.1161/CIRCIMAGING.114.001851 · DOI
10.1371/journal.pone.0089317 · DOI
10.1016/j.psym.2013.06.016 · DOI
10.1161/JAHA.114.001322 · DOI
10.1161/JAHA.116.004105 · DOI
10.1136/bmjopen-2016-012486 · DOI
10.1016/j.rmed.2017.08.001 · DOI
10.1161/JAHA.114.001494 · DOI
10.1161/JAHA.117.007234 · DOI
10.1016/j.ijcard.2018.07.107 · DOI
10.1161/JAHA.117.007658 · DOI
10.1161/JAHA.117.008424 · DOI
10.1016/j.ypmed.2019.105890 · DOI
10.1136/bmjopen-2017-019434 · DOI · Paper page
10.1519/JSC.0000000000003052 · DOI
10.1016/j.maturitas.2018.11.015 · DOI
10.1016/j.pmedr.2019.100922 · DOI
10.1016/j.ijcard.2015.05.007 · DOI
10.1016/j.healthplace.2017.01.005 · DOI
10.1016/j.amepre.2015.03.034 · DOI
10.1016/j.mayocp.2016.12.026 · DOI · Paper page
10.1001/jamanetworkopen.2019.4758 · DOI
10.1161/CIRCULATIONAHA.111.081083 · DOI · Paper page
10.1161/JAHA.116.003192 · DOI
10.1007/s00125-018-4792-y · DOI
10.1161/JAHA.116.005008 · DOI
10.1016/j.amepre.2015.07.039 · DOI
10.1161/CIRCULATIONAHA.112.001183 · DOI
10.1016/S0140-6736(20)30752-2 · DOI · Paper page
10.1016/S0140-6736(20)30925-9 · DOI · Paper page
10.1056/NEJMsa1211127 · DOI · Paper page
10.15585/mmwr.mm6806e1 · DOI
10.15585/mmwr.mm6845a2 · DOI
10.1056/NEJMp1805758 · DOI
10.15585/mmwr.ss6812a1 · DOI · Paper page
Drake, P, Driscoll, AK, Mathews, TJ. Cigarette smoking during pregnancy: United States, 2016. NCHS Data Brief. 20181–8.
10.1001/jamanetworkopen.2018.7794 · DOI
10.15585/mmwr.mm6744a2 · DOI
US Department of Health and Human Services. The Health Consequences of Smoking-50 Years of Progress: A Report of the Surgeon GeneralUS Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2014.
10.15585/mmwr.mm6544a2 · DOI
10.1016/j.amjmed.2019.12.020 · DOI
US Department of Health and Human Services. How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon GeneralUS Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health; 2010.
10.1186/s12889-015-1617-5 · DOI
10.1093/cid/civ013 · DOI
10.1161/STR.0000000000000046 · DOI · Paper page
10.1161/STROKEAHA.113.002342 · DOI
10.1177/2047487318806658 · DOI
10.1016/j.amjcard.2019.03.015 · DOI
10.3109/08958378.2016.1171934 · DOI
10.1093/aje/kwq191 · DOI
10.1161/CIR.0000000000000107 · DOI
10.1007/s12170-016-0505-6 · DOI
10.1016/j.tcm.2019.04.006 · DOI
10.1016/j.amepre.2018.05.004 · DOI
10.1016/j.amjmed.2019.02.016 · DOI
10.1016/j.biopsych.2018.11.024 · DOI
10.1038/s41380-018-0313-0 · DOI
10.1161/CIRCULATIONAHA.116.022069 · DOI
10.1136/tobaccocontrol-2014-052207 · DOI · Paper page
10.1093/ntr/ntz123 · DOI
10.1056/NEJMp1603294 · DOI
10.15585/mmwr.mm6828a1 · DOI
10.1161/JAHA.118.011307 · DOI
10.1001/jamanetworkopen.2019.4585 · DOI
10.1016/j.ahj.2019.03.019 · DOI
10.1001/jama.2019.10298 · DOI
10.1016/j.amepre.2008.04.009 · DOI · Paper page
10.1161/CIR.0000000000000678 · DOI · Paper page
10.1161/CIRCULATIONAHA.115.019634 · DOI
10.1016/S0140-6736(16)30272-0 · DOI · Paper page
10.1001/jamainternmed.2014.8313 · DOI
Centers for Disease Control and Prevention. Quitting smoking among adults–United States, 2001-2010. MMWR Morb Mortal Wkly Rep. 2011;60:1513–1519.
10.1016/j.amepre.2014.10.011 · DOI
10.1161/JAHA.113.000740 · DOI
10.1056/NEJMoa1808779 · DOI
10.1136/tobaccocontrol-2017-054108 · DOI
10.1001/jama.2018.0158 · DOI
10.1136/bmj.h1551 · DOI
10.1007/s10654-015-0031-8 · DOI
10.1161/CIR.0000000000000669 · DOI
10.7326/M18-1826 · DOI
Arrazola, RA, Singh, T, Corey, CG, Husten, CG, Neff, LJ, Apelberg, BJ, Bunnell, RE, Choiniere, CJ, King, BA, Cox, S, et al; Centers for Disease Control and Prevention (CDC). Tobacco use among middle and high school students–United States, 2011-2014. MMWR Morb Mortal Wkly Rep. 2015;64:381–385.
10.15585/mmwr.mm6710a3 · DOI · Paper page
10.1136/tobaccocontrol-2014-051670 · DOI
10.7326/M17-3440 · DOI
10.1093/ntr/ntz021 · DOI
Eaton, DL, Kwan, LY, Stratton, K, eds. Public Health Consequences of E-CigarettesWashington, DC: National Academies Press; 2018.
10.1093/ntr/nty089 · DOI
10.7326/M16-1107 · DOI · Paper page
10.7759/cureus.7088 · DOI
10.1001/jamanetworkopen.2019.16800 · DOI
10.1186/s12890-019-0950-3 · DOI
10.1016/j.amepre.2019.10.014 · DOI
10.1161/STROKEAHA.116.014099 · DOI
10.1016/j.ijcard.2015.07.011 · DOI
10.1371/journal.pone.0147848 · DOI
10.1016/j.jacc.2019.07.060 · DOI
10.1136/hrt.2010.199026 · DOI
Centers for Disease Control and Prevention. Vital signs: disparities in nonsmokers’ exposure to secondhand smoke–United States, 1999-2012. MMWR Morb Mortal Wkly Rep. 2015;64:103–108.
10.1016/j.amepre.2014.10.012 · DOI
10.1016/S0140-6736(18)32225-6 · DOI · Paper page
10.1016/S0140-6736(20)30752-2 · DOI · Paper page
10.15585/mmwr.mm6738a7 · DOI
10.1161/CIRCULATIONAHA.109.192703 · DOI · Paper page
US Department of Health and Human Services. Physical Activity Guidelines for Americans. 2nd ed. Department of Health and Human Services; 2018.
10.15585/mmwr.ss6708a1 · DOI · Paper page
10.1161/01.cir.0000435708.67487.da · DOI · Paper page
10.1161/CIR.0000000000000678 · DOI · Paper page
2018 Physical Activity Guidelines Advisory Committee. 2018 Physical Activity Guidelines Advisory Committee Scientific ReportUS Department of Health and Human Services; 2018.
10.1161/STR.0000000000000148 · DOI · Paper page
10.1001/jamaneurol.2017.1658 · DOI · Paper page
10.1016/j.amepre.2018.07.036 · DOI
10.1161/CIR.0b013e31827ee100 · DOI
10.1161/CIR.0000000000000461 · DOI · Paper page
10.1016/j.pcad.2014.09.008 · DOI
10.2471/BLT.18.213728 · DOI
10.1371/journal.pone.0115915 · DOI
Gahche, J, Fakhouri, T, Carroll, DD, Burt, VL, Wang, CY, Fulton, JE. Cardiorespiratory fitness levels among U.S. youth aged 12-15 years: United States, 1999-2004 and 2012. NCHS Data Brief. 20141–8.
10.1016/j.ypmed.2018.10.016 · DOI
Rideout, V. The Common Sense Census: Media Use by Kids Age Zero to EightCommon Sense Media; 2017. Accessed March 9, 2020. https://www.vjrconsulting.com/featured/2018/9/16/the-common-sense-census-media-use-by-kids-age-zero-to-eight-2017.
10.1542/peds.2016-2592 · DOI · Paper page
10.1016/j.amepre.2010.12.016 · DOI · Paper page
10.5888/pcd11.140189 · DOI
10.1186/s12966-017-0642-4 · DOI
The Nielsen Total Audience Report. 2019. Accessed October 20, 2020. https://www.nielsen.com/us/en/insights/article/2020/the-nielsen-total-audience-report-hub/.
10.1136/bjsports-2018-100056 · DOI · Paper page
10.1097/AOG.0000000000001214 · DOI
10.1249/MSS.0000000000001941 · DOI
10.1136/bjsports-2018-099399 · DOI
10.1016/j.amepre.2016.05.023 · DOI
10.1016/j.amepre.2018.07.008 · DOI
10.15585/mmwr.ss6407a1 · DOI
10.1001/jama.2018.17797 · DOI
10.1001/jama.2019.3636 · DOI
10.1016/j.amepre.2018.05.027 · DOI
Shifts in Viewing: The Cross-Platform Report: September 2014Nielsen Company; 2014.
10.1016/j.ypmed.2018.02.011 · DOI
10.1038/s41366-018-0120-3 · DOI · Paper page
10.1161/CIR.0000000000000440 · DOI · Paper page
10.1249/MSS.0000000000001607 · DOI
US Department of Health and Human Services. Step It Up! The Surgeon General’s Call to Action to Promote Walking and Walkable CommunitiesUS Dept of Health and Human Services, Office of the Surgeon General; 2015.
10.1001/jama.2016.5898 · DOI
10.1289/ehp.1510425 · DOI
Centers for Disease Control and Prevention and SHAPE America–Society of Health and Physical Educators. . Strategies for Recess in SchoolsCenters for Disease Control and Prevention, US Department of Health and Human Services; 2017.
10.1016/j.amepre.2015.06.022 · DOI
10.1249/MSS.0000000000001328 · DOI
10.5888/pcd18.170354 · DOI · Paper page
10.1136/bjsports-2014-094306 · DOI · Paper page
10.1001/jamainternmed.2015.0533 · DOI · Paper page
10.1161/JAHA.117.007677 · DOI
10.1007/s40279-018-1023-0 · DOI
10.1136/bmj.j1456 · DOI
10.1136/bjsports-2017-098540 · DOI · Paper page
10.1016/S0140-6736(16)30370-1 · DOI · Paper page
10.1093/aje/kwy125 · DOI
10.1016/j.amepre.2018.12.006 · DOI
10.1249/MSS.0000000000000885 · DOI
10.1249/MSS.0000000000001932 · DOI
10.1161/CIRCOUTCOMES.113.000531 · DOI
10.1016/j.ypmed.2019.105799 · DOI
10.1093/eurheartj/ehw249 · DOI
10.1038/ijo.2016.210 · DOI
10.3945/ajcn.116.150540 · DOI
10.1249/MSS.0000000000001310 · DOI
10.1080/02640414.2016.1260150 · DOI
10.1161/JAHA.116.004413 · DOI
10.1177/2047487314562741 · DOI
10.1161/HYPERTENSIONAHA.116.08994 · DOI
10.1249/MSS.0000000000001484 · DOI
Zwald, ML, Akinbami, LJ, Fakhouri, TH, Fryar, CD. Prevalence of low high-density lipoprotein cholesterol among adults, by physical activity: United States, 2011-2014. NCHS Data Brief. 20171–8.
10.1161/CIRCULATIONAHA.115.016938 · DOI
10.1161/CIRCULATIONAHA.116.026858 · DOI
10.1111/aogs.13151 · DOI

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Associations Among Digital Health Literacy, Lifestyle Factors, and Cardiovascular Health in Black and Hispanic Communities: Cross-Sectional Study
Chepkorir, J., Olawole, W., Miller, H., Adomako, N. O., Andrade, E. L., Cain, G. E., Baptiste, D., Ogungbe, O., Mullins, C. D., Clark, R., et al. (2025) · Journal of Medical Internet Research · doi:10.2196/60654 · Cited by 4
“Cardiovascular disease (CVD) remains the leading cause of death in the United States, with persistent racial and ethnic disparities in CVD risk, morbidity, and mortality [1].”
Time-restricted feeding mediated synchronization of circadian rhythms to sustain cardiovascular health
Melkani, G. C. (2025) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2025.07.007 · Cited by 7
Loss of joint individuation and abnormal synergy post stroke in upper limb movements
Koh, K., Oppizzi, G., Baghi, R., Kehs, G., & Zhang, L.-Q. (2025) · Neurorehabilitation and Neural Repair · doi:10.1177/15459683251340914 · Cited by 4
Serum OxLDL Levels Are Positively Associated with the Number of Ischemic Events and Damaged Blood Vessels in Patients with Coronary Artery Disease
Pérez-Robles, M., Campos-Pérez, W., Godínez-Mora, S., Lopez-Alvarez, V., Ramos-Villalobos, L. E., Corona-Ruiz, F., Armendáriz-Borunda, J., & Martínez-López, E. (2025) · Healthcare · doi:10.3390/healthcare13121426 · Cited by 4
“Moreover, 38.5% of participants were current moderate or heavy smokers—similar to the AHA-reported rate of 35% among high-risk cardiovascular patients [45].”
Influential
Scalable technologies in the manufacture and deployment of cell-free cardiac therapies.
Lundy, D. J., Burnouf, T., Lai, J. J., Hill, J. H., & Hsieh, P. C. H. (2025) · Trends in Biotechnology · doi:10.1016/j.tibtech.2025.05.016 · Cited by 4
Antiplatelet Therapy in Heart Disease
Özyüncü, N. (2025) · Reviews in Cardiovascular Medicine · doi:10.31083/rcm36522 · Cited by 9
“Antiplatelet therapy (APT), primarily consisting of aspirin (acetylsalicylic acid) and P2Y 12 receptor inhibitors, is one of the most commonly prescribed intervention in medicine [3].”
Research status and future perspectives of IL‑27 in the treatment of stroke (Review)
Liu, W., Zou, Z., Li, W., Yang, G., Zhang, J., Zhang, Z., & Yao, H. (2025) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2025.5557 · Cited by 3
The metabolic syndrome-insulin resistance index: a tool for identifying dyslipidemia across varied glucose metabolic score in patients with cardiovascular disease
Yu, L., Liu, Y.-T., Guo, R.-Y., Yang, T., Pan, G., He, Y.-Y., Gao, S., Yang, R.-R., Li, Z., Li, L., et al. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1473308 · Cited by 4
High-quality coronary artery segmentation via fuzzy logic modeling coupled with dynamic graph convolutional network
Dong, C., Dai, D.-W., Li, Y., & Xu, S.-Y. (2025) · Pattern Recognition · doi:10.1016/j.patcog.2025.111891 · Cited by 4
Strategies for the Secondary Prevention of Atherosclerotic Cardiovascular Disease
Hurwitz, M., Agboola, O. J., Gami, A., Williams, M. S., Virani, S. S., Sharma, G. V., & Patel, J. (2025) · US Cardiology Review · doi:10.15420/usc.2024.33 · Cited by 10
Self-citation
Biofabrication of small-diameter vascular graft with acellular human amniotic membrane: a proof-of-concept study in pig
Aung, O., Rossi, P. J., Zhai, Y., Allen, K. P., Dyer, M., Chang, J., Wang, X., Caswell, C., Stellpflug, A., Chen, Y., et al. (2025) · Biofabrication · doi:10.1088/1758-5090/adcb6d · Cited by 10
“…vascular grafts are critically needed for conditions such as peripheral artery disease (ID = 6 mm) [45], coronary artery disease (ID = 3–6 mm) [46], and hemodialysis access for end-stage renal disease (ID = 6 mm) [47], in which grafts with an ID of 6 mm are in highest clinical demand for…”
Association of systolic blood pressure target and variability with long-term clinical outcomes in patients undergoing percutaneous coronary intervention
Kim, B. S., Lim, Y., Shin, J., & Shin, J. (2025) · Clinical Hypertension · doi:10.5646/ch.2025.31.e13 · Cited by 4
“Coronary artery disease (CAD) is the most common type of heart disease and a leading cause of morbidity and mortality worldwide [1].”
Safety and Effectiveness of the High-Sensitivity HEART Pathway Safely Across Age Groups in Patients with Suspected Acute Coronary Syndrome.
Supples, M., Smits, S., Villenthi, A., Snavely, A., Ashburn, N., & Mahler, S. (2025) · American Journal of Cardiology · doi:10.1016/j.amjcard.2025.04.022 · Cited by 4
Predicting 28-Day Mortality in First-Time ICU Patients with Heart Failure and Hypertension Using LightGBM: A MIMIC-IV Study
Fan, J.-Y., Chen, S.-H., Pan, H.-N., Pishgar, E., Placencia, G., Alaei, K., & Pishgar, M. (2025) · medRxiv · doi:10.1101/2025.03.28.25324829 · Cited by 4
“According to the American Heart Association (AHA), approximately 6.2 million adults in the United States have heart failure, with an estimated 960,000 new cases diagnosed annually 1 .”
Influential
Trends and outcomes of heart failure hospitalizations during COVID-19 pandemic
Rubens, M., Ramamoorthy, V., Saxena, A., Khosla, A. A., Doke, M., McGranaghan, P., Appunni, S., Zhang, Y., Körfer, D., Chaparro, S. V., et al. (2025) · BMC Public Health · doi:10.1186/s12889-025-21995-y · Cited by 4
“The current prevalence of heart failure among US population is nearly 6 million, many of whom require hospitalizations for its management [3].”
A self-supervised semi-supervised echocardiographic video left ventricle segmentation method
Wang, T.-X., & Dai, Q. (2025) · Biomedical Signal Processing and Control · doi:10.1016/j.bspc.2024.107211 · Cited by 4
Eye Movement Detection using Electrooculography and Machine Learning in Cardiac Arrest Patients
Hill, C., Sykora, C. A., Schmugge, S., Tate, S., Cronin, M., Sisto, J., Mallinger, L. A., Reinert, A., Stafford, R., Tao, B. S., et al. (2025) · Resuscitation · doi:10.1016/j.resuscitation.2025.110577 · Cited by 4
Risk of Heart Failure in Patients With Immune-Mediated Inflammatory Diseases: A Population-Based Study
Koppikar, S., Kuriya, B., Udell, J. A., Yu, B., Chu, A., Lee, D., Widdifield, J., & Eder, L. (2025) · Journal of Rheumatology · doi:10.3899/jrheum.2024-0866 · Cited by 4
“12,13,16,39,46,47 Some of the sex differences may be explained by genetic cardiomyopathies, breast cancer treatment–induced HF, and peripartum cardio-myopathy.”
Does Adiponectin Inform Cardiovascular Risk in Older Adults?
Abushamat, L. A., Jia, X.-M., Xu, L., Cheng, C., Ndumele, C., Sun, C., Windham, B., Matsushita, K., Yu, B., Nambi, V., et al. (2025) · JACC: Advances · doi:10.1016/j.jacadv.2025.101625 · Cited by 4
Association between road traffic noise exposure and heart failure: A systematic review and meta-analysis of prospective cohort studies.
Liu, M., Chen, X., Zheng, G., Zhou, B., Fang, Z., Chen, H.-Y., Liang, X.-H., & Hao, G. (2025) · Public Health · doi:10.1016/j.puhe.2025.01.029 · Cited by 4
The mechanism of lncRNA PVT1 targeting the miR-30a/Beclin-1 axis to mediate ventricular remodeling in spontaneously hypertensive rats.
Ge, L., Ma, J.-J., Xu, J.-X., Wang, B., Adil, A., & Xu, H.-F. (2025) · Cellular Signalling · doi:10.1016/j.cellsig.2025.111650 · Cited by 4
Self-citation
Causal Effects of Sleep Traits on Angina Pectoris: Mediation by Cardiovascular Risk Factors
Zeng, C., Ke, Y., Li, H., Zhang, C., Chen, J., & Chen, M.-K. (2025) · Nature and Science of Sleep · doi:10.2147/nss.s484582 · Cited by 4
Stress and Anxiety Are Associated with Increased Metabolic Syndrome Risk Among Young Adults Living in the Deep South
Renna, M. E., Wilbourne, F. N., Johal, S. K., Fergerson, A. K., Behringer, K. F., Brandner, C. F., Stavres, J., & Graybeal, A. J. (2025) · Healthcare · doi:10.3390/healthcare13040359 · Cited by 4
“An estimated 659,000 American adults die from cardiovascular disease (CVD) annually [1].”
Gaps in Public Access Defibrillation
Kovoor, J., Jerrow, R., Cork, S., Page, G., Jui, J., Chugh, S., Finn, C., & Kovoor, P. (2025) · JACC: Advances · doi:10.1016/j.jacadv.2024.101573 · Cited by 4
Stroke Detection and Monitoring by Means of a Multifrequency Microwave Inversion Approach
Fedeli, A., Schenone, V., Estatico, C., & Randazzo, A. (2025) · Electronics · doi:10.3390/electronics14030543 · Cited by 4
“Moreover, since a relevant number of cases of the disease have recurrences, continuous monitoring with non-invasive techniques is often required in stroke-affected patients [1–3].”
IL-11 promotes Ang II-induced autophagy inhibition and mitochondrial dysfunction in atrial fibroblasts
Wang, J., Zhang, Q., Han, Y., Zhang, J., & Zheng, N. (2025) · Open Life Sciences · doi:10.1515/biol-2025-1063 · Cited by 2
“Atrial ﬁ brillation a ﬀ ects over 33 million people worldwide, and the incidence of the condition increases with age, with a prevalence of about 8.5% among patients over 65 [1,2].”
Influential
Multicenter study for CH-VAD as a fully magnetically levitated left ventricular assist device
Lu, Y., Zhao, S., Han, J., Lv, Q., Du, X., Hua, Z., Huang, K., Ge, Z.-W., Sun, X.-N., Zhu, D., et al. (2025) · iScience · doi:10.1016/j.isci.2025.111764 · Cited by 4
Therapeutic Potential Targeting Gut Microbiota Modulation With Emphasis on Lactobacillus spp. in Common Metabolic Disorders: A Systematic Review
Rahaman, M. M., Wangchuk, P., & Sarker, S. (2025) · Scientifica · doi:10.1155/sci5/3367875 · Cited by 5
Associations between Health-Related Social Needs and Postpartum Linkage to Care
Horwitz, M. E. M., Dugas, J. N., McCloskey, L., So‐Armah, K., Yarrington, C., de la Vega, P. B., Benjamin, E. J., & Battaglia, T. A. (2024) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2024.12.013 · Cited by 4
Self-citation
Physical training augmented with whole body electronic muscle stimulation favorably impacts cardiovascular biomarkers in healthy adults - A pilot randomized controlled trial.
Sara, J., Rajai, N., Ahmad, A., Breuer, L., Olson, T. P., Kemmler, W., Nagai, T., Schilaty, N. D., & Lerman, A. (2024) · International Journal of Cardiology · doi:10.1016/j.ijcard.2024.132706 · Cited by 4
Computational Fluid Dynamic Optimization of Micropatterned Surfaces: Towards Biofunctionalization of Artificial Organs
He, W.-X., Ibrahim, A. M., Karmakar, A., Tuli, S., Butcher, J. T., & Antaki, J. F. (2024) · Bioengineering · doi:10.3390/bioengineering11111092 · Cited by 4
LSTM-based ECG Signal Classification with Multi-level One-hot Encoding for Wearable Applications
Hu, J.-H., Goh, W.-L., & Gao, Y. (2024) · Biomedical Circuits and Systems Conference · doi:10.1109/biocas61083.2024.10798273 · Cited by 4
“However, some rare events like heart rate variability (HRV) and atrial fibrillation are not easy to capture during the routine medical checkups [2].”
Resistant Hypertension: A Brief Review of Pathophysiology
Haber, A., & Foy, A. (2024) · Journal of general internal medicine · doi:10.1007/s11606-024-09103-z · Cited by 4
“1,3,4 Other areas of ongoing interest in RH physiology aim to explore topics such as the pro-adrenergic and pro-inflammatory states of chronic diseases such as obstructive sleep apnea and chronic kidney disease to better understand how the physiologic changes induced in these conditions play a role…”
Interventional Therapies and Mechanical Circulatory Support for Acute Pulmonary Embolism.
Bali, A. D., Sharma, T., Villela, M. A., Naidu, S., & Goldberg, J. (2024) · Journal of Cardiac Failure · doi:10.1016/j.cardfail.2024.07.012 · Cited by 4
CLASSIFICATION OF HEART DISEASE USING THE K-NEAREST NEIGHBOR ALGORITHM AND LOGISTIC REGRESSION
Sugitha, I. K. A., Triayudi, A., & Handayani, E. T. E. (2024) · Jurnal Pilar Nusa Mandiri · doi:10.33480/pilar.v20i2.5742 · Cited by 4
“Despite medical advances reducing some risk factors like smoking and hypertension, the prevalence of other risks such as obesity and diabetes continues to rise (Virani et al., 2021).”
Association of Environmental and Behavioural Factors with Cardiovascular Disease Mortality
Açıktepe, B., Esirgün, S. N., & Koçak, M. (2024) · ESC Heart Failure · doi:10.1002/ehf2.14976 · Cited by 4
Correlation between triglyceride glucose index and coronary plaque: An observational study
Jia, H.-Y., Zhang, W.-F., Jia, S.-Q., Zhang, J., Xu, Z.-S., Xu, Z.-W., & Li, Y. (2024) · Medicine · doi:10.1097/md.0000000000039576 · Cited by 4
A Review of ECG Classification Techniques Based FPGA
Hamad, R. W., Gadawe, N. T., & Qaddoori, S. L. (2024) · Al-Salam Journal for Engineering and Technology · doi:10.55145/ajest.2025.04.01.008 · Cited by 4
“An ECG is a vital signal measured by healthcare devices, It detects electrical activity from the heart, providing valuable real-time insights for diagnosing potentially life-threatening heart problems [2].”
Background
Experimental studies of spiral wave teleportation in a light sensitive Belousov-Zhabotinsky system.
Tyler, S. A., Mersing, D., Fenton, F. H., Tinsley, M., & Showalter, K. (2024) · Chaos · doi:10.1063/5.0216649 · Cited by 4
NT-proBNP in Heart Failure with Preserved Ejection Fraction: A Comprehensive Review
Dsouza, G., & Sharma, M. (2024) · Indian Journal of Clinical Cardiology · doi:10.1177/26324636241261422 · Cited by 7
Lifestyle, air pollution, and risk of multimorbidity in a prospective analysis of the UK Biobank cohort
Chen, F., Yang, Y., Yu, L., Song, L., Zhang, J., Wang, X., Jin, X. J., Ma, W., & Zhang, B. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e35768 · Cited by 4
“Among these, ischaemic heart disease (IHD) is a leading cause of death worldwide [2], with 197.2 million people affected in 2019 [3].”
BackgroundInfluential
Mixtures of Urinary Phenol and Phthalate Metabolite Concentrations in Relation to Serum Lipid Levels among Pregnant Women: Results from the EARTH Study
Shen, X., Génard-Walton, M., Williams, P. L., James-Todd, T. M., Ford, J. B., Rexrode, K. M., Calafat, A. M., Zhang, D., Chavarro, J. E., Hauser, R. B., et al. (2024) · Toxics · doi:10.3390/toxics12080574 · Cited by 4
“Dyslipidemia is a well-known CVD risk factor characterized by high levels of triglycerides, total cholesterol and low-density lipoprotein (LDL), as well as lower levels of high-density lipoprotein (HDL), in the circulation [16].”
Background
Tissue versus mechanical mitral valve replacement in patients aged 50–70: a propensity-matched analysis
Fialka, N. M., Watkins, A. R., Alam, A. S., el-Andari, R., Kang, J. J. H., Hong, Y., Bozso, S., Moon, M. C., & Nagendran, J. (2024) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezae283 · Cited by 4
Brazilian Guideline for Exercise Testing in Children and Adolescents – 2024
de Carvalho, T., de Freitas, O. G. A., Chalela, W. A., Hossri, C. A. C., Milani, M., Buglia, S., Falcão, A. M. G. M., Costa, R. V. C., Ritt, L. E. F., Pfeiffer, M. E. T., et al. (2024) · Arquivos Brasileiros de Cardiologia · doi:10.36660/abc.20240525i · Cited by 3
M3: using mask-attention and multi-scale for multi-modal brain MRI classification
Kong, G., Wu, C., Zhang, Z., Yin, C., & Qin, D. (2024) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2024.1403732 · Cited by 5
Trends in heart failure costs for commercially insured patients in the United States (2006–2021)
Zheng, J., Abudayyeh, I., Rakovski, C., Ehwerhemuepha, L., Mianroodi, A. R., Patel, J., Ihab, A., & Ani, C. (2024) · BMC Health Services Research · doi:10.1186/s12913-024-11240-4 · Cited by 4
“In the USA, HF affects an estimated 6.9 million people [2], and its prevalence is expected to increase by 24% to nearly 8.5 million by 2030 [3].”
BackgroundInfluential
Biochemical Insights and Clinical Applications of Ischemia-Modified Albumin in Ischemic Conditions
Senadeera, N. N., Ranaweera, C., Perera, I. C., & Kottahachchi, D. (2024) · Journal of Vascular Diseases · doi:10.3390/jvd3030020 · Cited by 4
“Non-invasive in invasive tests [20].”
Long-term trends in lifestyle factors among respondents with dyslipidemia in the United States.
Bai, B.-Q., Liu, Q., Liu, Y.-T., Liu, F.-Y., Wang, Y., Chen, Y., Liang, Y.-T., Wang, H., Wu, C., Guo, L., et al. (2024) · American Journal of the Medical Sciences · doi:10.1016/j.amjms.2024.06.025 · Cited by 4
High Blood Pressure-Associated Symptoms: Insights From a Population-Based Study in Pakistan
Kidwai, S., Haris, M., Bilal, A., Saleem, S., Imran, H., Anwar, A., & Hashmi, A. (2024) · Cureus · doi:10.7759/cureus.65446 · Cited by 4
“This finding aligns with studies in Pakistan [7] and the United States [8], whereas it is in contrast with findings from Bangladesh [9], showing diverse gender distributions among hypertensive individuals.”
Result
Automatic motion estimation with applications to hiPSC-CMs
Finsberg, H., Charwat, V., Healy, K. E., & Wall, S. (2024) · Biomedical engineering and physics express · doi:10.1088/2057-1976/ad7268 · Cited by 4
“Cardiovascular diseases account for 1 out of 3 deaths in the US [1].”
Background
Design and control of a low-cost non-backdrivable end-effector upper limb rehabilitation device
Li, F., Guo, Y., Xu, W., Zhang, W., Zhao, F.-Y., Wang, B., Du, H., & Zhang, C. (2024) · Frontiers in Rehabilitation Sciences · doi:10.3389/fresc.2024.1469491 · Cited by 4
“By 2030, the prevalence rate is projected to increase to 3.9% [1], making stroke a major health concern in the US.”
BackgroundInfluential
Consistent cord blood DNA methylation signatures of gestational age between South Asian and white European cohorts
Deng, W. Q., Pigeyre, M., Azab, S. M., Wilson, S. L., Campbell, N., Cawte, N., Morrison, K. M., Atkinson, S. A., Subbarao, P., Turvey, S. E., et al. (2024) · Clinical Epigenetics · doi:10.1186/s13148-024-01684-0 · Cited by 4
“Certain racial groups, such as Black and Asian, are at a disadvantage as they have on average a shorter gestation duration [54] and are at a higher risk for pregnancy complications [55, 56].”
The Efficacy of Acupuncture Therapy in the Management of Dyspnea and Other Symptoms Associated with Heart Failure: A Consolidated Review of Trial Data
Ganglani, V., & Geng, Y. (2024) · Cells Tissues Organs · doi:10.1159/000539593 · Cited by 4
“Mortality due to cardiomyopathies has shown an increasing global trend due to improvement in “ diagnosis and documentation of speci ﬁ c cardiomyopathies and cardiotoxicity ” [33].”
Effects of Aromatherapy on Anxiety and Blood Pressure in Patients with Acute Coronary Syndrome: A Meta-Analysis of Randomized Controlled Trials
Kim, R. W., & Kim, M. (2024) · Journal of Integrative and Complementary Medicine · doi:10.1089/jicm.2023.0577 · Cited by 4
Costs Saved by Visiting a Nurse-Led Primary Care Facility Comparison of Primary Care Models
Wagner, L., & Rn, B. Z. P. (2024) · Policy, Politics & Nursing Practice · doi:10.1177/15271544241247767 · Cited by 4
“Blacks also experience higher rates of exacerbation and complications related to hypertension possibly due to lower proportion of patients that have their hypertension controlled (39.2% for Blacks vs. 48.6% for White) (Aggarwal et al., 2021b,a; Meador et al., 2020; Virani et al., 2021).”
Influential
Comparison of Short-Term Health Care Utilization Between Telemedicine-Delivered vs In-Person Care Visits for Heart Failure
Casey, S., Sax, D., Mark, D., Rana, J. S., Solomon, M. D., Huang, J., & Reed, M. E. (2024) · JACC: Advances · doi:10.1016/j.jacadv.2024.100969 · Cited by 4
Measuring the Influence of Side Effect Expectations, Beliefs, and Incident Side Effects on the Risk for Drug Discontinuation Among Individuals Starting New Medications, a Cross-sectional Study
Blackburn, D., Yao, S., Taylor, J., Alefan, Q., Lix, L., Eurich, D., & Choudhry, N. (2024) · Patient Preference and Adherence · doi:10.2147/ppa.s451012 · Cited by 4
Improvement of Neuronal and Cognitive Functions Following Treatment with 3',4' Dihydroxyflavonol in Experimental Focal Cerebral Ischemia-Reperfusion Injury in Rats.
Aladağ, T., Acar, G., Mogulkoc, R., & Baltacı, A. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176670 · Cited by 4
Number of Pregnancies and Risk of Atherosclerotic Cardiovascular Disease in Postmenopausal Women: A Cross-Sectional Study of NHANES from 1999 to 2018
Guo, J., Zhong, L.-L., Ding, S., Xiao, G.-T., Huang, M.-H., Zhang, L., & Chen, Q. (2024) · Journal of Women's Health · doi:10.1089/jwh.2023.0859 · Cited by 4
For Debate: The 2023 European Society of Hypertension guidelines - cause for concern
Shantsila, E., Beevers, D., & Lip, G. Y. (2024) · Journal of Hypertension · doi:10.1097/hjh.0000000000003733 · Cited by 4
Impact of inflammatory preconditioning on murine microglial proteome response induced by focal ischemic brain injury
Helbing, D. L., Haas, F., Cirri, E., Rahnis, N., Dau, T., Sacramento, E. K., Oraha, N., Böhm, L., Lajqi, T., Fehringer, P., et al. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1227355 · Cited by 7
Analyzing Existing Algorithms and Identifying Gaps in Brain Stroke Detection
Jadhav, R. B. (2024) · Journal of Electrical Systems · doi:10.52783/jes.1153 · Cited by 4
“The 350 stroke samples used to train the model led the researchers to suggest testing the model's performance with a bigger dataset [2][3][1].”
BackgroundMethod
Assessing the Diversity and Determinants of Health-Related Quality of Life Measures in Patients with Acute Heart Failure
Patil, D., Tang, H., Kuo, F., Toh, H. S., Yang, I., Chang, W., Lee, M., Chung, K., Huang, C., Hsu, W., et al. (2024) · ESC Heart Failure · doi:10.1002/ehf2.14745 · Cited by 4
Initiating and Continuing Long-Term Exercise in Heart Failure
Platz, K., Metzger, M., Cavanagh, C. E., Park, L., & Howie‐Esquivel, J. (2024) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0000000000001086 · Cited by 3
“38,39 In addition, these programs and the GENTLE-HF intervention represent innovative delivery of exercise that are less resource intensive and simultaneously increase exercise access.”
Systems of care for ambulatory management of decompensated heart failure
Badrish, N., Sheifer, S., & Rosner, C. M. (2024) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2024.1350846 · Cited by 4
Significance of abnormal stress electrocardiography with normal cardiac imaging during stress testing-a meta-analysis.
Mansour, M., Alqaisi, O., Gautam, N., & Vallurupalli, S. (2024) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2024.01.009 · Cited by 4
Treatment intensification with bempedoic acid to achieve LDL-C goal in patients with ASCVD: A simulation model using a real-world patient cohort in the US
Migliaccio-Walle, K., Elsea, D., Gupta, A., Sarnes, E., Griffith, K., Pandey, R., & Gillard, K. K. (2024) · Atherosclerosis Plus · doi:10.1016/j.athplu.2024.01.006 · Cited by 4
“Atherosclerotic cardiovascular disease (ASCVD) affects approximately 26 million Americans each year [1], resulting in 2 million hospitalizations and 400,000 deaths [2].”
Background
Silica nanoparticles enhance the cyto- and hemocompatibility of a multilayered extracellular matrix scaffold for vascular tissue regeneration
Goldberg, L. A., Zomer, H., McFetridge, C., & McFetridge, P. (2024) · Biotechnology Letters · doi:10.1007/s10529-023-03459-8 · Cited by 4
“(1234567890) new cases arise each year, with costs exceeding 5.5 billion dollars (Russell et al. 1998; Cheryl et al. 2012, 2020; Heron 2021; Virani et al. 2021).”
Influential
Bibliometric Analysis of the Role of Occludin in the Pathogenesis of Stroke
Urasheva, Z., Kabdrakhmanova, G., Yermagambetova, A., Utegenova, A. B., Seitmaganbetova, N., Aliyev, O. M., Kurmangaliyeva, S., Kenzhina, N. K., Kurmambayev, Y. Z., & Khamidulla, A. (2024) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2024/2121733 · Cited by 4
“Stroke remains a formidable global health challenge, ranking as the ﬁ fth leading cause of death and contributing to a substantial burden of disability worldwide [1].”
Background
The Association Between Geriatric Nutritional Risk Index and Readmission Within Six Months in Elderly Heart Failure Patients: A Retrospective Cohort Study
Dong, G., & Li, Z.-H. (2024) · Cardiology Research and Practice · doi:10.1155/2024/5692215 · Cited by 4
“Heart failure (HF) remains a global public health issue and is one of the leading causes of hospitalization in elderly people [1–3].”
Background
Riluzole is associated with reduced risk of heart failure
Kim, K., Kim, S., Katana, M., Terentyev, D., Radwański, P., & Munger, M. (2023) · medRxiv · doi:10.1111/ene.70033 · Cited by 4
“Heart failure (HF), a progressive continuum of ventricular dys - function, remains a major unsolved growing health and economic burden, despite therapeutic advances [ 1, 2].”
A contemporary review of snoRNAs in cardiovascular health: RNA modification and beyond
Jagielski, N., Rai, A. K., Rajan, K. S., Mangal, V., & Garikipati, V. (2023) · Molecular Therapy: Nucleic Acids · doi:10.1016/j.omtn.2023.102087 · Cited by 4
Effect of Frailty on the Long-Term Prognosis of Elderly Patients with Acute Myocardial Infarction
Zong, M., Guan, X., Huang, W., Chang, J., & Zhang, J. (2023) · Clinical Interventions in Aging · doi:10.2147/cia.s433221 · Cited by 4
Trends in Palliative Care Utilization in Deceased Veterans With Heart Failure
Wice, M., Rudolph, J. L., Jiang, L., Edmonson, H., Page, J., Wu, W.-C., & Defillo-Draiby, J. C. (2023) · Palliative Medicine Reports · doi:10.1089/pmr.2023.0067 · Cited by 4
Ventricular Remodeling Following Metabolic and Bariatric Surgery Decreases Need for Heart Transplantation: A Predictive Model
Rouhi, A. D., Choudhury, R. A., Hoeltzel, G., Ghanem, Y. K., Bababekov, Y., Suarez-Pierre, A., Yule, A., Vigneshwar, N., Williams, N. N., Dumon, K., et al. (2023) · Obesity Surgery · doi:10.1007/s11695-023-06948-x · Cited by 4
“As the prevalence of obesity and comorbidities linked to obesity, such as CHF and reduced EF, continues to rise in the US, optimal weight loss modalities to improve underlying cardiac pathology should be determined in this growing patient population [3–6].”
Association of Objective Sleep Characteristics and Incident Angina Pectoris: A Longitudinal Analysis from the Sleep Heart Health Study
Liu, J., Zhu, Y., Chang, Y.-H., Xu, Z., Wang, C., Zhang, P.-P., Li, S.-X., Yang, W., An, R., Wen, D., et al. (2023) · Nature and Science of Sleep · doi:10.2147/nss.s429231 · Cited by 4
“2 Therefore, identifying contributing factors to AP, and by extension CVD, carries profound public health implications.”
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“Stroke is a leading cause of long-term disability in the US and results in nearly USD 57 billion in medical expenses, including direct medical costs and indirect costs from premature mortality [2].”
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In-hospital mortality and cardiovascular treatment during hospitalization for heart failure among patients with schizophrenia: a nationwide cohort study
Nishi, M., Shikuma, A., Seki, T., Horiguchi, G., & Matoba, S. (2023) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796023000744 · Cited by 4
“Heart failure (HF) imposes enormous medical and economic burden on society, owing to its high morbidity and mortality rate (Storrow et al. , 2014; Virani et al. , 2021).”
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Effect of crew ratio of advanced life support-trained personnel on patients with out-of-hospital cardiac arrest: A systematic review and meta-analysis.
Wang, S.-A., Lee, H.-W., Ko, Y.-C., Sun, J.-T., Matsuyama, T., Lin, C.-H., Hsieh, M.-J., Chiang, W.-C., & Ma, M. (2023) · Journal of the Formosan Medical Association = Taiwan yi zhi · doi:10.1016/j.jfma.2023.10.008 · Cited by 4
Predictive Value of Carotid Plaque Contrast-Enhanced Ultrasound Score and Homocysteine in Senile Metabolic Syndrome Complicated by Cerebral Infarction.
Zuo, Z., Xu, Z.-G., Cheng, C.-F., Yang, S., & Li, M.-X. (2023) · Journal of the College of Physicians and Surgeons--Pakistan : JCPSP · doi:10.29271/jcpsp.2023.10.1100 · Cited by 4
“MetS is an important risk factor for cerebral infarction, and the incidence of cerebral infarction is higher in senile MetS patients.(3) The higher morbidity and disability rates pose a great threat to their health and quality of life.”
Background
Cardioprotective Effects of Aloysia polystachya Essential Oil on a Rat Model with Multiple Cardiovascular Risk Factors
Moreno, K. G. T., Marques, A. A. M., da Silva, G. D., Bertoncelo, L. A., Pessoal, L. B., Gonçalves, L. D., dos Santos, A. D., Souza, R. I., Silva, D. B., & Gasparotto, A. (2023) · Planta Medica · doi:10.1055/a-2294-6922 · Cited by 4
A 0.8 V, 14.76 nVrms, Multiplexer-Based AFE for Wearable Devices Using 45 nm CMOS Techniques
Esther, T., Duraisamy, G. N. R., Elangovan, M. K., & Samuel, T. S. A. (2023) · Micromachines · doi:10.3390/mi14101816 · Cited by 4
“.”
Perioperative Outcomes in Transcarotid Artery Revascularization Versus Carotid Endarterectomy or Stenting Nationwide
Ramsay, I., Burks, J., Lu, V. M., Silva, M. A., Abdelsalam, A., Starke, R., & Luther, E. (2023) · Operative Neurosurgery · doi:10.1227/ons.0000000000000865 · Cited by 4

Authors: Virani, S. S., Alonso, A., Aparicio, H. J., Benjamin, E. J., Bittencourt, M. S., Callaway, C. W., Carson, A. P., Chamberlain, A. M., Cheng, S., Delling, F. N., Elkind, M. S. V., Evenson, K. R., Ferguson, J. F., Gupta, D. K., Khan, S. S., Kissela, B. M., Knutson, K. L., Lee, C. D., Lewis, T. T., Liu, J., Loop, M. S., Lutsey, P. L., Ma, J., Mackey, J., Martin, S. S., Matchar, D. B., Mussolino, M. E., Navaneethan, S. D., Perak, A. M., Roth, G. A., Samad, Z., Satou, G. M., Schroeder, E. B., Shah, S. H., Shay, C. M., Stokes, A., VanWagner, L. B., Wang, N.-Y., Tsao, C. W., & On behalf of the American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee
ORCID: Virani, Salim S.
Aparicio, Hugo J.
Benjamin, Emelia J.
Callaway, Clifton W.
Carson, April P.
Chamberlain, Alanna M.
Cheng, Susan
Delling, Francesca N.
Elkind, Mitchell S.V.
Evenson, Kelly R.
Ferguson, Jane F.
Gupta, Deepak K.
Khan, Sadiya S.
Knutson, Kristen L.
Lee, Chong D.
Lewis, Tené T.
Liu, Junxiu
Loop, Matthew Shane
Lutsey, Pamela L.
Ma, Jun
Mackey, Jason
Martin, Seth S.
Matchar, David B.
Navaneethan, Sankar D.
Perak, Amanda Marma
Roth, Gregory A.
Samad, Zainab
Satou, Gary M.
Schroeder, Emily B.
Shah, Svati H.
Shay, Christina M.
Stokes, Andrew
VanWagner, Lisa B.
Wang, Nae-Yuh
Tsao, Connie W.
Venue: Circulation
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2021-02-23
Volume: 143
Issue: 8
Pages: e254-e743
ISSN: 0009-7322 (ISSN-L)
1524-4539
DOI: 10.1161/cir.0000000000000950
PMC: PMC13036842
OpenAlex: W3122226502
Cited by: 5,784
References: 0
Citations by year: 2026: 503 · 2025: 658 · 2024: 915 · 2023: 1282 · 2022: 1694 · 2021: 646
FWCI: 764.95
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Circulation (publishedVersion)
PubMed (publishedVersion)
PubMed Central (publishedVersion, cc-by-nc-nd)
eCommons - AKU (Aga Khan University) (submittedVersion)
Funders: National Heart, Lung, and Blood Institute (R03HL145195, R01HL155717)
National Institute of Neurological Disorders and Stroke (L30 NS093634, R01NS017950)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
Keywords: heart disease, stroke, cardiovascular disease statistics, cardiovascular risk factors, cardiovascular health behaviors, congenital heart disease, rhythm disorders, subclinical atherosclerosis, coronary artery disease, heart failure, valvular heart disease, venous disease, peripheral arterial disease, quality of care, health care costs, social determinants of health, adverse pregnancy outcomes, cardiovascular disease prevention
MeSH terms: Global Burden of Disease, Diet, Healthy, American Heart Association, Blood Pressure, Cholesterol, Diabetes Mellitus, Heart Diseases, Hospitalization, Humans, Obesity, Risk Factors, Smoking, United States, Health Behavior, Exercise, Prevalence, Stroke

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